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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for IRX3
Z-value: 1.65
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Transcription factors associated with IRX3
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
IRX3
|
ENSG00000177508.11 | iroquois homeobox 3 |
Activity profile of IRX3 motif
Sorted Z-values of IRX3 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr12_-_91574142 | 51.27 |
ENST00000547937.1
|
DCN
|
decorin |
| chr12_-_91573132 | 47.06 |
ENST00000550563.1
ENST00000546370.1 |
DCN
|
decorin |
| chr8_+_84824920 | 46.35 |
ENST00000523678.1
|
RP11-120I21.2
|
RP11-120I21.2 |
| chr13_-_88323218 | 44.48 |
ENST00000436290.2
ENST00000453832.2 ENST00000606590.1 |
MIR4500HG
|
MIR4500 host gene (non-protein coding) |
| chr12_-_91573316 | 37.64 |
ENST00000393155.1
|
DCN
|
decorin |
| chr12_-_91546926 | 34.07 |
ENST00000550758.1
|
DCN
|
decorin |
| chr16_-_30032610 | 33.47 |
ENST00000574405.1
|
DOC2A
|
double C2-like domains, alpha |
| chr12_-_91573249 | 33.44 |
ENST00000550099.1
ENST00000546391.1 ENST00000551354.1 |
DCN
|
decorin |
| chr5_+_54320078 | 32.22 |
ENST00000231009.2
|
GZMK
|
granzyme K (granzyme 3; tryptase II) |
| chr7_+_20686946 | 25.37 |
ENST00000443026.2
ENST00000406935.1 |
ABCB5
|
ATP-binding cassette, sub-family B (MDR/TAP), member 5 |
| chr17_-_29641084 | 23.55 |
ENST00000544462.1
|
EVI2B
|
ecotropic viral integration site 2B |
| chr14_-_21945057 | 23.11 |
ENST00000397762.1
|
RAB2B
|
RAB2B, member RAS oncogene family |
| chr9_-_116102530 | 22.99 |
ENST00000374195.3
ENST00000341761.4 |
WDR31
|
WD repeat domain 31 |
| chr2_-_89545079 | 22.42 |
ENST00000468494.1
|
IGKV2-30
|
immunoglobulin kappa variable 2-30 |
| chr11_+_57365150 | 22.37 |
ENST00000457869.1
ENST00000340687.6 ENST00000378323.4 ENST00000378324.2 ENST00000403558.1 |
SERPING1
|
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
| chr12_-_9268707 | 22.06 |
ENST00000318602.7
|
A2M
|
alpha-2-macroglobulin |
| chr2_-_136875712 | 21.74 |
ENST00000241393.3
|
CXCR4
|
chemokine (C-X-C motif) receptor 4 |
| chr4_+_106631966 | 20.91 |
ENST00000360505.5
ENST00000510865.1 ENST00000509336.1 |
GSTCD
|
glutathione S-transferase, C-terminal domain containing |
| chr9_+_105757590 | 20.86 |
ENST00000374798.3
ENST00000487798.1 |
CYLC2
|
cylicin, basic protein of sperm head cytoskeleton 2 |
| chr3_-_122283100 | 20.27 |
ENST00000492382.1
ENST00000462315.1 |
PARP9
|
poly (ADP-ribose) polymerase family, member 9 |
| chr10_-_90712520 | 19.85 |
ENST00000224784.6
|
ACTA2
|
actin, alpha 2, smooth muscle, aorta |
| chr11_-_111782696 | 19.84 |
ENST00000227251.3
ENST00000526180.1 |
CRYAB
|
crystallin, alpha B |
| chr7_-_150020578 | 19.81 |
ENST00000478393.1
|
ACTR3C
|
ARP3 actin-related protein 3 homolog C (yeast) |
| chr9_-_116102562 | 19.74 |
ENST00000374193.4
ENST00000465979.1 |
WDR31
|
WD repeat domain 31 |
| chr2_+_89975669 | 19.28 |
ENST00000474213.1
|
IGKV2D-30
|
immunoglobulin kappa variable 2D-30 |
| chr1_+_46668994 | 18.62 |
ENST00000371980.3
|
LURAP1
|
leucine rich adaptor protein 1 |
| chr16_-_75498553 | 18.40 |
ENST00000569276.1
ENST00000357613.4 ENST00000561878.1 ENST00000566980.1 ENST00000567194.1 |
TMEM170A
RP11-77K12.1
|
transmembrane protein 170A Uncharacterized protein |
| chr19_+_9296279 | 17.86 |
ENST00000344248.2
|
OR7D2
|
olfactory receptor, family 7, subfamily D, member 2 |
| chr4_-_186125077 | 17.81 |
ENST00000458385.2
ENST00000514798.1 ENST00000296775.6 |
KIAA1430
|
KIAA1430 |
| chr12_-_71182695 | 17.74 |
ENST00000342084.4
|
PTPRR
|
protein tyrosine phosphatase, receptor type, R |
| chr1_+_26644441 | 17.71 |
ENST00000374213.2
|
CD52
|
CD52 molecule |
| chr6_-_52705641 | 17.69 |
ENST00000370989.2
|
GSTA5
|
glutathione S-transferase alpha 5 |
| chr2_+_111490161 | 17.19 |
ENST00000340561.4
|
ACOXL
|
acyl-CoA oxidase-like |
| chr11_-_5255861 | 15.92 |
ENST00000380299.3
|
HBD
|
hemoglobin, delta |
| chr1_+_117297007 | 15.71 |
ENST00000369478.3
ENST00000369477.1 |
CD2
|
CD2 molecule |
| chr6_-_49834209 | 15.67 |
ENST00000507853.1
|
CRISP1
|
cysteine-rich secretory protein 1 |
| chr11_+_61891445 | 15.37 |
ENST00000394818.3
ENST00000533896.1 ENST00000278849.4 |
INCENP
|
inner centromere protein antigens 135/155kDa |
| chr1_+_158259558 | 15.28 |
ENST00000368170.3
|
CD1C
|
CD1c molecule |
| chr17_-_18585541 | 15.02 |
ENST00000285274.5
ENST00000545289.1 ENST00000580145.1 |
ZNF286B
|
zinc finger protein 286B |
| chr12_+_10365404 | 14.79 |
ENST00000266458.5
ENST00000421801.2 ENST00000544284.1 ENST00000545047.1 ENST00000543602.1 ENST00000545887.1 |
GABARAPL1
|
GABA(A) receptor-associated protein like 1 |
| chr4_+_88754069 | 14.73 |
ENST00000395102.4
ENST00000497649.2 |
MEPE
|
matrix extracellular phosphoglycoprotein |
| chr3_+_122044084 | 14.66 |
ENST00000264474.3
ENST00000479204.1 |
CSTA
|
cystatin A (stefin A) |
| chr2_+_90139056 | 14.64 |
ENST00000492446.1
|
IGKV1D-16
|
immunoglobulin kappa variable 1D-16 |
| chr5_-_177207634 | 14.60 |
ENST00000513554.1
ENST00000440605.3 |
FAM153A
|
family with sequence similarity 153, member A |
| chr1_-_153029980 | 14.55 |
ENST00000392653.2
|
SPRR2A
|
small proline-rich protein 2A |
| chr17_-_29641104 | 14.39 |
ENST00000577894.1
ENST00000330927.4 |
EVI2B
|
ecotropic viral integration site 2B |
| chr12_+_133757995 | 14.06 |
ENST00000536435.2
ENST00000228289.5 ENST00000541211.2 ENST00000500625.3 ENST00000539248.2 ENST00000542711.2 ENST00000536899.2 ENST00000542986.2 ENST00000537565.1 ENST00000541975.2 |
ZNF268
|
zinc finger protein 268 |
| chr12_-_10251603 | 14.05 |
ENST00000457018.2
|
CLEC1A
|
C-type lectin domain family 1, member A |
| chr15_+_66585555 | 13.62 |
ENST00000319194.5
ENST00000525134.2 ENST00000441424.2 |
DIS3L
|
DIS3 mitotic control homolog (S. cerevisiae)-like |
| chr3_-_48936272 | 13.57 |
ENST00000544097.1
ENST00000430379.1 ENST00000319017.4 |
SLC25A20
|
solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 |
| chr1_+_22964073 | 13.52 |
ENST00000402322.1
|
C1QA
|
complement component 1, q subcomponent, A chain |
| chr1_+_196788887 | 13.43 |
ENST00000320493.5
ENST00000367424.4 ENST00000367421.3 |
CFHR1
CFHR2
|
complement factor H-related 1 complement factor H-related 2 |
| chr6_-_49834240 | 13.12 |
ENST00000335847.4
|
CRISP1
|
cysteine-rich secretory protein 1 |
| chr12_+_21679220 | 13.09 |
ENST00000256969.2
|
C12orf39
|
chromosome 12 open reading frame 39 |
| chr7_+_40174565 | 12.88 |
ENST00000309930.5
ENST00000401647.2 ENST00000335693.4 ENST00000413931.1 ENST00000416370.1 ENST00000540834.1 |
C7orf10
|
succinylCoA:glutarate-CoA transferase |
| chr1_+_52870227 | 12.77 |
ENST00000257181.9
|
PRPF38A
|
pre-mRNA processing factor 38A |
| chr1_+_202317815 | 12.49 |
ENST00000608999.1
ENST00000336894.4 ENST00000480184.1 |
PPP1R12B
|
protein phosphatase 1, regulatory subunit 12B |
| chr2_-_196933536 | 12.48 |
ENST00000312428.6
ENST00000410072.1 |
DNAH7
|
dynein, axonemal, heavy chain 7 |
| chrX_+_153639856 | 12.10 |
ENST00000426834.1
ENST00000369790.4 ENST00000454722.1 ENST00000350743.4 ENST00000299328.5 ENST00000351413.4 |
TAZ
|
tafazzin |
| chr6_+_127587755 | 12.01 |
ENST00000368314.1
ENST00000476956.1 ENST00000609447.1 ENST00000356799.2 ENST00000477776.1 ENST00000609944.1 |
RNF146
|
ring finger protein 146 |
| chr20_+_54933971 | 11.87 |
ENST00000371384.3
ENST00000437418.1 |
FAM210B
|
family with sequence similarity 210, member B |
| chr11_-_118213331 | 11.78 |
ENST00000392884.2
|
CD3D
|
CD3d molecule, delta (CD3-TCR complex) |
| chr13_+_97928395 | 11.76 |
ENST00000445661.2
|
MBNL2
|
muscleblind-like splicing regulator 2 |
| chr2_+_189839046 | 11.70 |
ENST00000304636.3
ENST00000317840.5 |
COL3A1
|
collagen, type III, alpha 1 |
| chr17_-_47755338 | 11.69 |
ENST00000508805.1
ENST00000515508.2 ENST00000451526.2 ENST00000507970.1 |
SPOP
|
speckle-type POZ protein |
| chr12_+_32655048 | 11.57 |
ENST00000427716.2
ENST00000266482.3 |
FGD4
|
FYVE, RhoGEF and PH domain containing 4 |
| chr16_+_67840668 | 11.53 |
ENST00000415766.3
|
TSNAXIP1
|
translin-associated factor X interacting protein 1 |
| chr11_-_111782484 | 11.48 |
ENST00000533971.1
|
CRYAB
|
crystallin, alpha B |
| chr8_+_12803176 | 11.46 |
ENST00000524591.2
|
KIAA1456
|
KIAA1456 |
| chr14_+_95047725 | 11.37 |
ENST00000554760.1
ENST00000554866.1 ENST00000329597.7 ENST00000556775.1 |
SERPINA5
|
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| chr14_+_95047744 | 11.04 |
ENST00000553511.1
ENST00000554633.1 ENST00000555681.1 ENST00000554276.1 |
SERPINA5
|
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| chr7_+_55086703 | 10.98 |
ENST00000455089.1
ENST00000342916.3 ENST00000344576.2 ENST00000420316.2 |
EGFR
|
epidermal growth factor receptor |
| chrX_+_15767971 | 10.94 |
ENST00000479740.1
ENST00000454127.2 |
CA5B
|
carbonic anhydrase VB, mitochondrial |
| chr11_-_118213455 | 10.83 |
ENST00000300692.4
|
CD3D
|
CD3d molecule, delta (CD3-TCR complex) |
| chr5_+_147443534 | 10.81 |
ENST00000398454.1
ENST00000359874.3 ENST00000508733.1 ENST00000256084.7 |
SPINK5
|
serine peptidase inhibitor, Kazal type 5 |
| chr1_+_22778337 | 10.74 |
ENST00000404138.1
ENST00000400239.2 ENST00000375647.4 ENST00000374651.4 |
ZBTB40
|
zinc finger and BTB domain containing 40 |
| chr2_+_113816215 | 10.73 |
ENST00000346807.3
|
IL36RN
|
interleukin 36 receptor antagonist |
| chr3_+_171561127 | 10.73 |
ENST00000334567.5
ENST00000450693.1 |
TMEM212
|
transmembrane protein 212 |
| chr8_+_27631903 | 10.62 |
ENST00000305188.8
|
ESCO2
|
establishment of sister chromatid cohesion N-acetyltransferase 2 |
| chr16_+_31539197 | 10.51 |
ENST00000564707.1
|
AHSP
|
alpha hemoglobin stabilizing protein |
| chr12_-_10542617 | 10.44 |
ENST00000240618.6
|
KLRK1
|
killer cell lectin-like receptor subfamily K, member 1 |
| chr22_+_51176624 | 10.40 |
ENST00000216139.5
ENST00000529621.1 |
ACR
|
acrosin |
| chr19_-_40919271 | 10.39 |
ENST00000291825.7
ENST00000324001.7 |
PRX
|
periaxin |
| chr4_-_80329356 | 10.37 |
ENST00000358842.3
|
GK2
|
glycerol kinase 2 |
| chr10_-_103815874 | 10.32 |
ENST00000370033.4
ENST00000311122.5 |
C10orf76
|
chromosome 10 open reading frame 76 |
| chr12_+_69742121 | 10.26 |
ENST00000261267.2
ENST00000549690.1 ENST00000548839.1 |
LYZ
|
lysozyme |
| chr14_-_106926724 | 10.11 |
ENST00000434710.1
|
IGHV3-43
|
immunoglobulin heavy variable 3-43 |
| chr3_+_53528659 | 10.09 |
ENST00000350061.5
|
CACNA1D
|
calcium channel, voltage-dependent, L type, alpha 1D subunit |
| chr12_-_95467267 | 10.04 |
ENST00000330677.7
|
NR2C1
|
nuclear receptor subfamily 2, group C, member 1 |
| chr2_+_90121477 | 10.02 |
ENST00000483379.1
|
IGKV1D-17
|
immunoglobulin kappa variable 1D-17 |
| chr11_-_35547572 | 9.94 |
ENST00000378880.2
|
PAMR1
|
peptidase domain containing associated with muscle regeneration 1 |
| chr13_+_25338290 | 9.89 |
ENST00000255324.5
ENST00000381921.1 ENST00000255325.6 |
RNF17
|
ring finger protein 17 |
| chr3_-_183543301 | 9.80 |
ENST00000318631.3
ENST00000431348.1 |
MAP6D1
|
MAP6 domain containing 1 |
| chr3_+_8543533 | 9.72 |
ENST00000454244.1
|
LMCD1
|
LIM and cysteine-rich domains 1 |
| chr12_-_66524482 | 9.48 |
ENST00000446587.2
ENST00000266604.2 |
LLPH
|
LLP homolog, long-term synaptic facilitation (Aplysia) |
| chr3_+_138066539 | 9.42 |
ENST00000289104.4
|
MRAS
|
muscle RAS oncogene homolog |
| chrX_-_140673133 | 9.36 |
ENST00000370519.3
|
SPANXA1
|
sperm protein associated with the nucleus, X-linked, family member A1 |
| chr19_+_55281260 | 9.25 |
ENST00000336077.6
ENST00000291633.7 |
KIR2DL1
|
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 |
| chr5_+_175490540 | 9.16 |
ENST00000515817.1
|
FAM153B
|
family with sequence similarity 153, member B |
| chr11_+_60739115 | 9.14 |
ENST00000344028.5
ENST00000346437.4 |
CD6
|
CD6 molecule |
| chr11_+_111783450 | 9.12 |
ENST00000537382.1
|
HSPB2
|
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA. |
| chr16_+_48657361 | 9.09 |
ENST00000565072.1
|
RP11-42I10.1
|
RP11-42I10.1 |
| chr20_-_18477862 | 9.07 |
ENST00000337227.4
|
RBBP9
|
retinoblastoma binding protein 9 |
| chr11_+_89764274 | 8.96 |
ENST00000448984.1
ENST00000432771.1 |
TRIM49C
|
tripartite motif containing 49C |
| chr11_+_111782934 | 8.95 |
ENST00000304298.3
|
HSPB2
|
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA. |
| chr19_+_55591743 | 8.92 |
ENST00000588359.1
ENST00000245618.5 |
EPS8L1
|
EPS8-like 1 |
| chr3_+_186383741 | 8.82 |
ENST00000232003.4
|
HRG
|
histidine-rich glycoprotein |
| chr14_+_22386325 | 8.81 |
ENST00000390439.2
|
TRAV13-2
|
T cell receptor alpha variable 13-2 |
| chr12_-_9360966 | 8.73 |
ENST00000261336.2
|
PZP
|
pregnancy-zone protein |
| chr1_-_23504176 | 8.72 |
ENST00000302291.4
|
LUZP1
|
leucine zipper protein 1 |
| chrX_+_76709648 | 8.62 |
ENST00000439435.1
|
FGF16
|
fibroblast growth factor 16 |
| chr17_-_34207295 | 8.55 |
ENST00000463941.1
ENST00000293272.3 |
CCL5
|
chemokine (C-C motif) ligand 5 |
| chr1_+_196912902 | 8.50 |
ENST00000476712.2
ENST00000367415.5 |
CFHR2
|
complement factor H-related 2 |
| chr12_-_10007448 | 8.46 |
ENST00000538152.1
|
CLEC2B
|
C-type lectin domain family 2, member B |
| chr2_-_89459813 | 8.35 |
ENST00000390256.2
|
IGKV6-21
|
immunoglobulin kappa variable 6-21 (non-functional) |
| chr14_-_107131560 | 8.29 |
ENST00000390632.2
|
IGHV3-66
|
immunoglobulin heavy variable 3-66 |
| chr11_+_113258495 | 8.24 |
ENST00000303941.3
|
ANKK1
|
ankyrin repeat and kinase domain containing 1 |
| chr10_+_13628933 | 8.20 |
ENST00000417658.1
ENST00000320054.4 |
PRPF18
|
pre-mRNA processing factor 18 |
| chr13_+_53226963 | 8.19 |
ENST00000343788.6
ENST00000535397.1 ENST00000310528.8 |
SUGT1
|
SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) |
| chr15_-_51630772 | 8.15 |
ENST00000557858.1
ENST00000558328.1 ENST00000396404.4 ENST00000561075.1 ENST00000405011.2 ENST00000559980.1 ENST00000453807.2 ENST00000396402.1 |
CYP19A1
|
cytochrome P450, family 19, subfamily A, polypeptide 1 |
| chr15_+_25200074 | 8.11 |
ENST00000390687.4
ENST00000584968.1 ENST00000346403.6 ENST00000554227.2 |
SNRPN
|
small nuclear ribonucleoprotein polypeptide N |
| chr2_-_242041607 | 8.09 |
ENST00000434791.1
ENST00000401626.2 ENST00000439144.1 ENST00000406593.1 ENST00000495694.1 ENST00000407095.3 ENST00000391980.2 |
MTERFD2
|
MTERF domain containing 2 |
| chr1_+_158985457 | 8.09 |
ENST00000567661.1
ENST00000474473.1 |
IFI16
|
interferon, gamma-inducible protein 16 |
| chr1_-_52870104 | 8.08 |
ENST00000371568.3
|
ORC1
|
origin recognition complex, subunit 1 |
| chr16_+_33204156 | 8.06 |
ENST00000398667.4
|
TP53TG3C
|
TP53 target 3C |
| chr15_-_83680325 | 8.06 |
ENST00000508990.2
ENST00000510873.2 ENST00000538348.2 ENST00000451195.3 ENST00000513601.2 ENST00000304177.5 ENST00000565712.1 |
C15orf40
|
chromosome 15 open reading frame 40 |
| chr12_-_11422739 | 7.94 |
ENST00000279573.7
|
PRB3
|
proline-rich protein BstNI subfamily 3 |
| chr16_+_67840986 | 7.94 |
ENST00000561639.1
ENST00000567852.1 ENST00000565148.1 ENST00000388833.3 ENST00000561654.1 ENST00000431934.2 |
TSNAXIP1
|
translin-associated factor X interacting protein 1 |
| chr19_-_45004556 | 7.88 |
ENST00000587047.1
ENST00000391956.4 ENST00000221327.4 ENST00000586637.1 ENST00000591064.1 ENST00000592529.1 |
ZNF180
|
zinc finger protein 180 |
| chr19_-_52531600 | 7.88 |
ENST00000356322.6
ENST00000270649.6 |
ZNF614
|
zinc finger protein 614 |
| chr1_-_7913089 | 7.83 |
ENST00000361696.5
|
UTS2
|
urotensin 2 |
| chr5_-_95297678 | 7.79 |
ENST00000237853.4
|
ELL2
|
elongation factor, RNA polymerase II, 2 |
| chr1_-_16302565 | 7.78 |
ENST00000537142.1
ENST00000448462.2 |
ZBTB17
|
zinc finger and BTB domain containing 17 |
| chr11_-_47870091 | 7.75 |
ENST00000526870.1
|
NUP160
|
nucleoporin 160kDa |
| chr15_-_56757329 | 7.73 |
ENST00000260453.3
|
MNS1
|
meiosis-specific nuclear structural 1 |
| chr5_+_54455946 | 7.71 |
ENST00000503787.1
ENST00000296734.6 ENST00000515370.1 |
GPX8
|
glutathione peroxidase 8 (putative) |
| chr14_-_106692191 | 7.70 |
ENST00000390607.2
|
IGHV3-21
|
immunoglobulin heavy variable 3-21 |
| chr2_-_201729284 | 7.58 |
ENST00000434813.2
|
CLK1
|
CDC-like kinase 1 |
| chr2_-_16804320 | 7.57 |
ENST00000355549.2
|
FAM49A
|
family with sequence similarity 49, member A |
| chr13_+_96085847 | 7.57 |
ENST00000376873.3
|
CLDN10
|
claudin 10 |
| chr6_+_26204825 | 7.55 |
ENST00000360441.4
|
HIST1H4E
|
histone cluster 1, H4e |
| chr1_+_196857144 | 7.48 |
ENST00000367416.2
ENST00000251424.4 ENST00000367418.2 |
CFHR4
|
complement factor H-related 4 |
| chr2_+_85921414 | 7.47 |
ENST00000263863.4
ENST00000524600.1 |
GNLY
|
granulysin |
| chr1_+_53308398 | 7.43 |
ENST00000371528.1
|
ZYG11A
|
zyg-11 family member A, cell cycle regulator |
| chrX_+_83116142 | 7.39 |
ENST00000329312.4
|
CYLC1
|
cylicin, basic protein of sperm head cytoskeleton 1 |
| chr1_+_44584522 | 7.30 |
ENST00000372299.3
|
KLF17
|
Kruppel-like factor 17 |
| chr16_+_84209539 | 7.28 |
ENST00000569735.1
|
DNAAF1
|
dynein, axonemal, assembly factor 1 |
| chr22_+_23161491 | 7.23 |
ENST00000390316.2
|
IGLV3-9
|
immunoglobulin lambda variable 3-9 (gene/pseudogene) |
| chr5_-_93447333 | 7.23 |
ENST00000395965.3
ENST00000505869.1 ENST00000509163.1 |
FAM172A
|
family with sequence similarity 172, member A |
| chr4_+_75023816 | 7.21 |
ENST00000395759.2
ENST00000331145.6 ENST00000359107.5 ENST00000325278.6 |
MTHFD2L
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| chr20_-_44600810 | 7.21 |
ENST00000322927.2
ENST00000426788.1 |
ZNF335
|
zinc finger protein 335 |
| chr2_+_85921522 | 7.21 |
ENST00000409696.3
|
GNLY
|
granulysin |
| chr2_-_201936302 | 7.18 |
ENST00000453765.1
ENST00000452799.1 ENST00000446678.1 ENST00000418596.3 |
FAM126B
|
family with sequence similarity 126, member B |
| chr15_-_81616446 | 7.08 |
ENST00000302824.6
|
STARD5
|
StAR-related lipid transfer (START) domain containing 5 |
| chr22_-_36556821 | 7.06 |
ENST00000531095.1
ENST00000397293.2 ENST00000349314.2 |
APOL3
|
apolipoprotein L, 3 |
| chr2_-_89521942 | 7.06 |
ENST00000482769.1
|
IGKV2-28
|
immunoglobulin kappa variable 2-28 |
| chr11_+_114166536 | 7.05 |
ENST00000299964.3
|
NNMT
|
nicotinamide N-methyltransferase |
| chrX_-_6453159 | 7.03 |
ENST00000381089.3
ENST00000398729.1 |
VCX3A
|
variable charge, X-linked 3A |
| chr12_+_106751436 | 6.99 |
ENST00000228347.4
|
POLR3B
|
polymerase (RNA) III (DNA directed) polypeptide B |
| chr19_+_55327923 | 6.94 |
ENST00000391728.4
ENST00000326542.7 ENST00000358178.4 |
KIR3DL1
|
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 |
| chr18_-_28622774 | 6.93 |
ENST00000434452.1
|
DSC3
|
desmocollin 3 |
| chr9_-_100684845 | 6.93 |
ENST00000375119.3
|
C9orf156
|
chromosome 9 open reading frame 156 |
| chr2_-_152589670 | 6.89 |
ENST00000604864.1
ENST00000603639.1 |
NEB
|
nebulin |
| chr16_+_1578674 | 6.85 |
ENST00000253934.5
|
TMEM204
|
transmembrane protein 204 |
| chr12_+_9102632 | 6.82 |
ENST00000539240.1
|
KLRG1
|
killer cell lectin-like receptor subfamily G, member 1 |
| chr1_+_152975488 | 6.81 |
ENST00000542696.1
|
SPRR3
|
small proline-rich protein 3 |
| chr10_+_60272814 | 6.80 |
ENST00000373886.3
|
BICC1
|
bicaudal C homolog 1 (Drosophila) |
| chr11_+_60739140 | 6.78 |
ENST00000313421.7
|
CD6
|
CD6 molecule |
| chr3_-_149470229 | 6.73 |
ENST00000473414.1
|
COMMD2
|
COMM domain containing 2 |
| chr22_+_23154239 | 6.68 |
ENST00000390315.2
|
IGLV3-10
|
immunoglobulin lambda variable 3-10 |
| chrX_+_150866779 | 6.68 |
ENST00000370353.3
|
PRRG3
|
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) |
| chr7_-_38289173 | 6.67 |
ENST00000436911.2
|
TRGC2
|
T cell receptor gamma constant 2 |
| chr5_-_59481406 | 6.64 |
ENST00000546160.1
|
PDE4D
|
phosphodiesterase 4D, cAMP-specific |
| chr17_+_34431212 | 6.64 |
ENST00000394495.1
|
CCL4
|
chemokine (C-C motif) ligand 4 |
| chr14_-_106963409 | 6.64 |
ENST00000390621.2
|
IGHV1-45
|
immunoglobulin heavy variable 1-45 |
| chr11_-_49230184 | 6.63 |
ENST00000340334.7
ENST00000256999.2 |
FOLH1
|
folate hydrolase (prostate-specific membrane antigen) 1 |
| chr4_+_70146217 | 6.62 |
ENST00000335568.5
ENST00000511240.1 |
UGT2B28
|
UDP glucuronosyltransferase 2 family, polypeptide B28 |
| chr7_-_99573640 | 6.62 |
ENST00000411734.1
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding |
| chr7_-_4901625 | 6.59 |
ENST00000404991.1
|
PAPOLB
|
poly(A) polymerase beta (testis specific) |
| chr1_+_160709029 | 6.50 |
ENST00000444090.2
ENST00000441662.2 |
SLAMF7
|
SLAM family member 7 |
| chr4_-_141348999 | 6.46 |
ENST00000325617.5
|
CLGN
|
calmegin |
| chr17_+_34430980 | 6.46 |
ENST00000250151.4
|
CCL4
|
chemokine (C-C motif) ligand 4 |
| chr11_+_60739249 | 6.43 |
ENST00000542157.1
ENST00000433107.2 ENST00000452451.2 ENST00000352009.5 |
CD6
|
CD6 molecule |
| chr5_-_115872142 | 6.39 |
ENST00000510263.1
|
SEMA6A
|
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
| chr15_-_22473353 | 6.38 |
ENST00000557788.2
|
IGHV4OR15-8
|
immunoglobulin heavy variable 4/OR15-8 (non-functional) |
| chr2_-_127963343 | 6.38 |
ENST00000335247.7
|
CYP27C1
|
cytochrome P450, family 27, subfamily C, polypeptide 1 |
| chr11_-_118305921 | 6.37 |
ENST00000532619.1
|
RP11-770J1.4
|
RP11-770J1.4 |
| chr11_-_118213360 | 6.36 |
ENST00000529594.1
|
CD3D
|
CD3d molecule, delta (CD3-TCR complex) |
| chr9_-_95298314 | 6.34 |
ENST00000344604.5
ENST00000375540.1 |
ECM2
|
extracellular matrix protein 2, female organ and adipocyte specific |
| chr2_-_99771373 | 6.34 |
ENST00000393483.3
|
TSGA10
|
testis specific, 10 |
| chr22_-_29457832 | 6.33 |
ENST00000216071.4
|
C22orf31
|
chromosome 22 open reading frame 31 |
| chr17_+_18380051 | 6.32 |
ENST00000581545.1
ENST00000582333.1 ENST00000328114.6 ENST00000412421.2 ENST00000583322.1 ENST00000584941.1 |
LGALS9C
|
lectin, galactoside-binding, soluble, 9C |
| chr22_+_40297105 | 6.31 |
ENST00000540310.1
|
GRAP2
|
GRB2-related adaptor protein 2 |
| chr1_+_215747118 | 6.28 |
ENST00000448333.1
|
KCTD3
|
potassium channel tetramerization domain containing 3 |
| chr8_+_120885949 | 6.22 |
ENST00000523492.1
ENST00000286234.5 |
DEPTOR
|
DEP domain containing MTOR-interacting protein |
| chr12_-_10282836 | 6.18 |
ENST00000304084.8
ENST00000353231.5 ENST00000525605.1 |
CLEC7A
|
C-type lectin domain family 7, member A |
| chr4_+_71600144 | 6.18 |
ENST00000502653.1
|
RUFY3
|
RUN and FYVE domain containing 3 |
| chr21_+_41239243 | 6.15 |
ENST00000328619.5
|
PCP4
|
Purkinje cell protein 4 |
| chr11_-_85376121 | 6.12 |
ENST00000527447.1
|
CREBZF
|
CREB/ATF bZIP transcription factor |
| chr11_-_104480019 | 6.10 |
ENST00000536529.1
ENST00000545630.1 ENST00000538641.1 |
RP11-886D15.1
|
RP11-886D15.1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of IRX3
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 17.7 | 212.3 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 6.3 | 25.4 | GO:0048749 | compound eye development(GO:0048749) |
| 5.9 | 17.6 | GO:0045897 | positive regulation of transcription during mitosis(GO:0045897) |
| 4.9 | 14.7 | GO:0002818 | intracellular defense response(GO:0002818) |
| 4.5 | 22.4 | GO:0061107 | seminal vesicle development(GO:0061107) |
| 3.7 | 11.0 | GO:0043006 | activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006) |
| 3.6 | 32.1 | GO:2000501 | regulation of natural killer cell chemotaxis(GO:2000501) |
| 3.4 | 44.4 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 3.4 | 20.3 | GO:0070212 | protein poly-ADP-ribosylation(GO:0070212) |
| 3.3 | 19.9 | GO:0090131 | mesenchyme migration(GO:0090131) |
| 3.1 | 21.7 | GO:0019064 | fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800) |
| 3.0 | 12.1 | GO:0032049 | cardiolipin biosynthetic process(GO:0032049) |
| 3.0 | 17.7 | GO:1903385 | regulation of homophilic cell adhesion(GO:1903385) |
| 2.8 | 19.3 | GO:1902715 | positive regulation of interferon-gamma secretion(GO:1902715) |
| 2.7 | 8.2 | GO:2000861 | negative regulation of macrophage chemotaxis(GO:0010760) estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864) |
| 2.7 | 10.8 | GO:1900425 | negative regulation of defense response to bacterium(GO:1900425) |
| 2.6 | 10.4 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
| 2.5 | 5.0 | GO:2001183 | negative regulation of interleukin-12 secretion(GO:2001183) |
| 2.2 | 29.0 | GO:0045059 | positive thymic T cell selection(GO:0045059) |
| 2.2 | 28.8 | GO:0007342 | fusion of sperm to egg plasma membrane(GO:0007342) |
| 2.1 | 6.3 | GO:0009107 | lipoate biosynthetic process(GO:0009107) |
| 2.1 | 10.3 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
| 2.0 | 5.9 | GO:1903487 | regulation of lactation(GO:1903487) |
| 2.0 | 7.8 | GO:0042320 | regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) |
| 2.0 | 5.9 | GO:0042113 | B cell activation(GO:0042113) |
| 1.8 | 14.4 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 1.8 | 19.8 | GO:0036159 | inner dynein arm assembly(GO:0036159) |
| 1.8 | 10.7 | GO:1902714 | negative regulation of interferon-gamma secretion(GO:1902714) |
| 1.8 | 25.0 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
| 1.8 | 5.3 | GO:1990523 | bone regeneration(GO:1990523) |
| 1.7 | 31.3 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 1.7 | 6.9 | GO:0007525 | somatic muscle development(GO:0007525) |
| 1.7 | 25.6 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 1.7 | 9.9 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 1.6 | 3.3 | GO:0050916 | sensory perception of sweet taste(GO:0050916) |
| 1.6 | 6.4 | GO:0032053 | ciliary basal body organization(GO:0032053) |
| 1.6 | 4.8 | GO:1903935 | response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936) |
| 1.5 | 9.3 | GO:0002765 | immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767) |
| 1.5 | 4.5 | GO:0043163 | cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229) |
| 1.5 | 10.4 | GO:0007341 | penetration of zona pellucida(GO:0007341) |
| 1.5 | 5.9 | GO:0010961 | cellular magnesium ion homeostasis(GO:0010961) |
| 1.5 | 8.8 | GO:0052422 | modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422) |
| 1.5 | 23.4 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
| 1.4 | 2.9 | GO:1904468 | negative regulation of tumor necrosis factor secretion(GO:1904468) |
| 1.4 | 7.2 | GO:0009256 | 10-formyltetrahydrofolate metabolic process(GO:0009256) |
| 1.4 | 10.1 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
| 1.4 | 5.7 | GO:0002503 | peptide antigen assembly with MHC class II protein complex(GO:0002503) |
| 1.4 | 9.8 | GO:0006498 | N-terminal protein lipidation(GO:0006498) |
| 1.4 | 2.8 | GO:1900005 | positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573) |
| 1.3 | 5.4 | GO:1902159 | regulation of cyclic nucleotide-gated ion channel activity(GO:1902159) |
| 1.3 | 4.0 | GO:0070171 | negative regulation of tooth mineralization(GO:0070171) |
| 1.3 | 11.8 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 1.3 | 15.3 | GO:0048003 | antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007) |
| 1.3 | 11.5 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
| 1.3 | 3.8 | GO:0019626 | short-chain fatty acid catabolic process(GO:0019626) |
| 1.3 | 3.8 | GO:0019605 | benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605) |
| 1.2 | 18.6 | GO:0015671 | oxygen transport(GO:0015671) |
| 1.2 | 8.6 | GO:1904849 | positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546) |
| 1.2 | 3.6 | GO:0071934 | thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934) |
| 1.2 | 4.6 | GO:0005986 | sucrose biosynthetic process(GO:0005986) |
| 1.2 | 4.6 | GO:0019470 | 4-hydroxyproline catabolic process(GO:0019470) |
| 1.1 | 18.4 | GO:0071786 | endoplasmic reticulum tubular network organization(GO:0071786) |
| 1.1 | 6.6 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
| 1.1 | 10.5 | GO:0010886 | positive regulation of cholesterol storage(GO:0010886) |
| 1.0 | 71.4 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 1.0 | 3.1 | GO:0006711 | estrogen catabolic process(GO:0006711) |
| 1.0 | 16.5 | GO:0042574 | retinal metabolic process(GO:0042574) |
| 1.0 | 4.1 | GO:0010966 | regulation of phosphate transport(GO:0010966) |
| 1.0 | 7.1 | GO:0035376 | sterol import(GO:0035376) cholesterol import(GO:0070508) |
| 1.0 | 22.2 | GO:0030502 | negative regulation of bone mineralization(GO:0030502) negative regulation of biomineral tissue development(GO:0070168) |
| 1.0 | 5.0 | GO:0003051 | angiotensin-mediated drinking behavior(GO:0003051) |
| 1.0 | 4.0 | GO:0003095 | pressure natriuresis(GO:0003095) |
| 1.0 | 6.0 | GO:0048241 | epinephrine transport(GO:0048241) |
| 1.0 | 93.5 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.9 | 2.7 | GO:0045643 | regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) |
| 0.9 | 44.5 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.9 | 14.8 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.9 | 3.5 | GO:0002408 | myeloid dendritic cell chemotaxis(GO:0002408) |
| 0.9 | 5.1 | GO:0097267 | omega-hydroxylase P450 pathway(GO:0097267) |
| 0.8 | 5.9 | GO:0001180 | transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180) |
| 0.8 | 32.5 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.8 | 3.3 | GO:0021784 | postganglionic parasympathetic fiber development(GO:0021784) |
| 0.8 | 3.2 | GO:0017198 | N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920) |
| 0.8 | 5.5 | GO:0001915 | negative regulation of T cell mediated cytotoxicity(GO:0001915) |
| 0.8 | 7.6 | GO:0018210 | peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210) |
| 0.8 | 2.3 | GO:0002581 | negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) |
| 0.7 | 3.7 | GO:0030035 | microspike assembly(GO:0030035) |
| 0.7 | 3.7 | GO:0008210 | estrogen metabolic process(GO:0008210) |
| 0.7 | 6.6 | GO:0086024 | adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) |
| 0.7 | 5.1 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.7 | 8.7 | GO:0001842 | neural fold formation(GO:0001842) |
| 0.7 | 4.1 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) |
| 0.7 | 5.4 | GO:0030299 | intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856) |
| 0.6 | 3.2 | GO:0033504 | floor plate development(GO:0033504) |
| 0.6 | 7.0 | GO:0034356 | NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356) |
| 0.6 | 5.1 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 0.6 | 3.8 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) |
| 0.6 | 12.7 | GO:0006853 | carnitine shuttle(GO:0006853) |
| 0.6 | 10.1 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.6 | 1.2 | GO:0002434 | immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) |
| 0.6 | 11.4 | GO:0020027 | hemoglobin metabolic process(GO:0020027) |
| 0.6 | 4.8 | GO:2000660 | negative regulation of interleukin-1-mediated signaling pathway(GO:2000660) |
| 0.6 | 7.7 | GO:0070986 | left/right axis specification(GO:0070986) |
| 0.6 | 2.4 | GO:0002329 | pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331) |
| 0.6 | 8.9 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.6 | 15.2 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.6 | 1.7 | GO:0038043 | interleukin-5-mediated signaling pathway(GO:0038043) |
| 0.6 | 2.9 | GO:2000676 | positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
| 0.6 | 5.7 | GO:0006069 | ethanol oxidation(GO:0006069) |
| 0.6 | 10.3 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 0.6 | 5.7 | GO:0060174 | limb bud formation(GO:0060174) |
| 0.6 | 1.7 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
| 0.6 | 5.7 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 0.6 | 6.2 | GO:0045792 | negative regulation of cell size(GO:0045792) |
| 0.6 | 4.4 | GO:0016139 | glycoside catabolic process(GO:0016139) |
| 0.5 | 2.2 | GO:0030242 | pexophagy(GO:0030242) |
| 0.5 | 2.2 | GO:0071221 | response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221) |
| 0.5 | 2.7 | GO:0099590 | exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967) neurotransmitter receptor internalization(GO:0099590) |
| 0.5 | 3.7 | GO:0051597 | response to methylmercury(GO:0051597) |
| 0.5 | 4.7 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.5 | 13.5 | GO:0071168 | protein localization to chromatin(GO:0071168) |
| 0.5 | 7.2 | GO:0080182 | histone H3-K4 trimethylation(GO:0080182) |
| 0.5 | 2.5 | GO:0030070 | insulin processing(GO:0030070) |
| 0.5 | 9.6 | GO:0010248 | establishment or maintenance of transmembrane electrochemical gradient(GO:0010248) |
| 0.5 | 16.6 | GO:0045730 | respiratory burst(GO:0045730) |
| 0.5 | 13.5 | GO:0001702 | gastrulation with mouth forming second(GO:0001702) |
| 0.5 | 2.5 | GO:0034197 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
| 0.5 | 1.5 | GO:0071048 | nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048) |
| 0.5 | 10.4 | GO:0070493 | thrombin receptor signaling pathway(GO:0070493) |
| 0.5 | 2.8 | GO:0002278 | eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) |
| 0.5 | 4.7 | GO:0003373 | dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374) |
| 0.5 | 12.6 | GO:0097484 | dendrite extension(GO:0097484) |
| 0.5 | 3.2 | GO:0098704 | fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539) |
| 0.5 | 3.2 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
| 0.5 | 19.8 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 0.4 | 2.2 | GO:0061767 | negative regulation of lung blood pressure(GO:0061767) |
| 0.4 | 20.0 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.4 | 2.2 | GO:0044241 | lipid digestion(GO:0044241) |
| 0.4 | 1.7 | GO:2000232 | regulation of ribosome biogenesis(GO:0090069) regulation of rRNA processing(GO:2000232) |
| 0.4 | 5.1 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
| 0.4 | 2.5 | GO:0003228 | atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009) |
| 0.4 | 2.0 | GO:0045903 | positive regulation of translational fidelity(GO:0045903) |
| 0.4 | 1.6 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653) |
| 0.4 | 1.2 | GO:0006063 | uronic acid metabolic process(GO:0006063) glucuronate metabolic process(GO:0019585) cellular glucuronidation(GO:0052695) |
| 0.4 | 3.9 | GO:1904424 | regulation of GTP binding(GO:1904424) |
| 0.4 | 1.2 | GO:0002740 | negative regulation of cytokine secretion involved in immune response(GO:0002740) |
| 0.4 | 3.8 | GO:0070129 | regulation of mitochondrial translation(GO:0070129) |
| 0.4 | 1.5 | GO:1900003 | regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572) |
| 0.4 | 4.1 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 0.4 | 4.5 | GO:0048194 | Golgi vesicle budding(GO:0048194) |
| 0.4 | 1.5 | GO:0035425 | autocrine signaling(GO:0035425) |
| 0.4 | 3.3 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.4 | 4.0 | GO:0035457 | cellular response to interferon-alpha(GO:0035457) |
| 0.4 | 7.2 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
| 0.4 | 22.0 | GO:0042267 | natural killer cell mediated cytotoxicity(GO:0042267) |
| 0.3 | 4.9 | GO:0002455 | humoral immune response mediated by circulating immunoglobulin(GO:0002455) |
| 0.3 | 13.8 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.3 | 1.4 | GO:0061358 | negative regulation of Wnt protein secretion(GO:0061358) |
| 0.3 | 4.1 | GO:0018108 | peptidyl-tyrosine phosphorylation(GO:0018108) |
| 0.3 | 2.4 | GO:0002371 | dendritic cell cytokine production(GO:0002371) |
| 0.3 | 3.0 | GO:0043950 | positive regulation of cAMP-mediated signaling(GO:0043950) |
| 0.3 | 1.0 | GO:0044205 | 'de novo' UMP biosynthetic process(GO:0044205) |
| 0.3 | 16.3 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
| 0.3 | 10.5 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) |
| 0.3 | 2.6 | GO:2001013 | epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013) |
| 0.3 | 2.6 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.3 | 1.5 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.3 | 6.2 | GO:2000114 | regulation of establishment of cell polarity(GO:2000114) |
| 0.3 | 3.7 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.3 | 5.8 | GO:0030889 | negative regulation of B cell proliferation(GO:0030889) |
| 0.3 | 5.0 | GO:0060219 | camera-type eye photoreceptor cell differentiation(GO:0060219) |
| 0.3 | 7.4 | GO:0044364 | killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) |
| 0.3 | 3.2 | GO:0046600 | negative regulation of centriole replication(GO:0046600) |
| 0.3 | 4.1 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
| 0.3 | 41.0 | GO:0002377 | immunoglobulin production(GO:0002377) |
| 0.3 | 8.4 | GO:0050710 | negative regulation of cytokine secretion(GO:0050710) |
| 0.3 | 2.1 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 0.3 | 2.7 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
| 0.3 | 7.5 | GO:0030449 | regulation of complement activation(GO:0030449) |
| 0.3 | 20.7 | GO:0045921 | positive regulation of exocytosis(GO:0045921) |
| 0.3 | 7.6 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.3 | 1.6 | GO:0009082 | branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099) |
| 0.3 | 2.0 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 0.2 | 2.2 | GO:0043435 | response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376) |
| 0.2 | 0.5 | GO:0032499 | positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499) |
| 0.2 | 4.3 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.2 | 1.6 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
| 0.2 | 5.8 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 0.2 | 6.8 | GO:0001945 | lymph vessel development(GO:0001945) |
| 0.2 | 18.3 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
| 0.2 | 2.0 | GO:0097186 | amelogenesis(GO:0097186) |
| 0.2 | 5.0 | GO:0010390 | histone monoubiquitination(GO:0010390) |
| 0.2 | 12.0 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.2 | 5.5 | GO:0032731 | positive regulation of interleukin-1 beta production(GO:0032731) |
| 0.2 | 3.9 | GO:0034505 | tooth mineralization(GO:0034505) |
| 0.2 | 4.6 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
| 0.2 | 5.0 | GO:0036152 | phosphatidylethanolamine acyl-chain remodeling(GO:0036152) |
| 0.2 | 2.2 | GO:0060539 | diaphragm development(GO:0060539) |
| 0.2 | 1.6 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
| 0.2 | 1.6 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.2 | 7.0 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.2 | 4.3 | GO:0043277 | apoptotic cell clearance(GO:0043277) |
| 0.2 | 1.9 | GO:0036120 | negative regulation of fibroblast migration(GO:0010764) response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120) |
| 0.2 | 5.6 | GO:0034219 | carbohydrate transmembrane transport(GO:0034219) |
| 0.2 | 17.7 | GO:0006749 | glutathione metabolic process(GO:0006749) |
| 0.2 | 5.5 | GO:0097120 | receptor localization to synapse(GO:0097120) |
| 0.2 | 16.3 | GO:0070268 | cornification(GO:0070268) |
| 0.2 | 8.9 | GO:0050829 | defense response to Gram-negative bacterium(GO:0050829) |
| 0.2 | 1.7 | GO:0008595 | tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595) |
| 0.2 | 12.1 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.2 | 1.8 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
| 0.2 | 4.0 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.2 | 2.7 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.2 | 1.4 | GO:0034454 | microtubule anchoring at centrosome(GO:0034454) |
| 0.2 | 18.2 | GO:0048232 | spermatogenesis(GO:0007283) male gamete generation(GO:0048232) |
| 0.2 | 3.9 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
| 0.1 | 2.4 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
| 0.1 | 2.4 | GO:0001502 | cartilage condensation(GO:0001502) |
| 0.1 | 7.1 | GO:0001895 | retina homeostasis(GO:0001895) |
| 0.1 | 3.2 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.1 | 4.9 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
| 0.1 | 4.3 | GO:0022400 | regulation of rhodopsin mediated signaling pathway(GO:0022400) |
| 0.1 | 3.2 | GO:0002092 | positive regulation of receptor internalization(GO:0002092) |
| 0.1 | 0.4 | GO:0003344 | pericardium morphogenesis(GO:0003344) |
| 0.1 | 0.7 | GO:0014005 | microglia differentiation(GO:0014004) microglia development(GO:0014005) cellular response to norepinephrine stimulus(GO:0071874) |
| 0.1 | 1.0 | GO:0038180 | nerve growth factor signaling pathway(GO:0038180) |
| 0.1 | 3.5 | GO:0043551 | regulation of phosphatidylinositol 3-kinase activity(GO:0043551) |
| 0.1 | 2.7 | GO:0070262 | peptidyl-serine dephosphorylation(GO:0070262) |
| 0.1 | 2.1 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.1 | 4.3 | GO:0048016 | inositol phosphate-mediated signaling(GO:0048016) |
| 0.1 | 0.6 | GO:0006987 | activation of signaling protein activity involved in unfolded protein response(GO:0006987) |
| 0.1 | 2.1 | GO:0035810 | positive regulation of urine volume(GO:0035810) |
| 0.1 | 0.5 | GO:0042699 | follicle-stimulating hormone signaling pathway(GO:0042699) |
| 0.1 | 2.9 | GO:0043243 | positive regulation of protein complex disassembly(GO:0043243) |
| 0.1 | 10.0 | GO:0016575 | histone deacetylation(GO:0016575) |
| 0.1 | 7.8 | GO:0030282 | bone mineralization(GO:0030282) |
| 0.1 | 2.0 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.1 | 0.3 | GO:0019442 | tryptophan catabolic process to acetyl-CoA(GO:0019442) |
| 0.1 | 0.9 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 0.1 | 1.7 | GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) |
| 0.1 | 7.7 | GO:0098869 | cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748) |
| 0.1 | 11.6 | GO:0016925 | protein sumoylation(GO:0016925) |
| 0.1 | 2.5 | GO:0035640 | exploration behavior(GO:0035640) |
| 0.1 | 0.8 | GO:1903358 | regulation of Golgi organization(GO:1903358) |
| 0.1 | 1.4 | GO:0042100 | B cell proliferation(GO:0042100) |
| 0.1 | 9.9 | GO:0007286 | spermatid development(GO:0007286) |
| 0.1 | 13.4 | GO:0006937 | regulation of muscle contraction(GO:0006937) |
| 0.1 | 1.2 | GO:0070306 | lens fiber cell differentiation(GO:0070306) |
| 0.1 | 2.8 | GO:0007601 | visual perception(GO:0007601) sensory perception of light stimulus(GO:0050953) |
| 0.1 | 5.0 | GO:0060337 | type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357) |
| 0.1 | 1.6 | GO:0014912 | negative regulation of smooth muscle cell migration(GO:0014912) |
| 0.1 | 0.5 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 0.1 | 4.1 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.1 | 4.4 | GO:0006805 | xenobiotic metabolic process(GO:0006805) |
| 0.1 | 0.8 | GO:0090311 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) regulation of protein deacetylation(GO:0090311) |
| 0.1 | 0.5 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 0.1 | 2.9 | GO:0046626 | regulation of insulin receptor signaling pathway(GO:0046626) |
| 0.1 | 1.3 | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) |
| 0.1 | 8.9 | GO:0008366 | ensheathment of neurons(GO:0007272) axon ensheathment(GO:0008366) |
| 0.1 | 1.1 | GO:0050890 | cognition(GO:0050890) |
| 0.1 | 2.4 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
| 0.1 | 0.8 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.1 | 0.9 | GO:0032331 | negative regulation of chondrocyte differentiation(GO:0032331) |
| 0.1 | 4.3 | GO:0045814 | negative regulation of gene expression, epigenetic(GO:0045814) |
| 0.1 | 1.1 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.1 | 2.5 | GO:0051438 | regulation of ubiquitin-protein transferase activity(GO:0051438) |
| 0.1 | 2.1 | GO:0042059 | negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) |
| 0.1 | 0.2 | GO:0070857 | regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251) |
| 0.1 | 0.8 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
| 0.1 | 2.1 | GO:0045739 | positive regulation of DNA repair(GO:0045739) |
| 0.1 | 2.5 | GO:0031175 | neuron projection development(GO:0031175) |
| 0.1 | 1.1 | GO:0042632 | cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092) |
| 0.1 | 1.6 | GO:0051496 | positive regulation of stress fiber assembly(GO:0051496) |
| 0.0 | 0.6 | GO:0043691 | reverse cholesterol transport(GO:0043691) |
| 0.0 | 6.9 | GO:0007219 | Notch signaling pathway(GO:0007219) |
| 0.0 | 0.5 | GO:0051281 | positive regulation of release of sequestered calcium ion into cytosol(GO:0051281) |
| 0.0 | 3.4 | GO:0006094 | gluconeogenesis(GO:0006094) |
| 0.0 | 0.7 | GO:0042403 | thyroid hormone metabolic process(GO:0042403) |
| 0.0 | 0.6 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.0 | 0.9 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058) |
| 0.0 | 1.5 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
| 0.0 | 0.7 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
| 0.0 | 10.7 | GO:0045666 | positive regulation of neuron differentiation(GO:0045666) |
| 0.0 | 1.5 | GO:0045576 | mast cell activation(GO:0045576) |
| 0.0 | 2.1 | GO:0006879 | cellular iron ion homeostasis(GO:0006879) |
| 0.0 | 1.0 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
| 0.0 | 2.4 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
| 0.0 | 0.7 | GO:0046426 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.0 | 0.9 | GO:0036297 | interstrand cross-link repair(GO:0036297) |
| 0.0 | 2.9 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.0 | 2.0 | GO:0007270 | neuron-neuron synaptic transmission(GO:0007270) |
| 0.0 | 0.3 | GO:0003009 | skeletal muscle contraction(GO:0003009) |
| 0.0 | 0.3 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.0 | 1.1 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) |
| 0.0 | 3.6 | GO:0007265 | Ras protein signal transduction(GO:0007265) |
| 0.0 | 1.7 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 0.0 | 1.2 | GO:0050680 | negative regulation of epithelial cell proliferation(GO:0050680) |
| 0.0 | 0.6 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.0 | 0.4 | GO:0019933 | cAMP-mediated signaling(GO:0019933) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 14.5 | 203.5 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 9.4 | 28.2 | GO:0033011 | perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150) |
| 7.5 | 22.4 | GO:0097182 | protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183) |
| 5.2 | 10.4 | GO:0043159 | acrosomal matrix(GO:0043159) |
| 5.0 | 19.9 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 3.7 | 11.0 | GO:0097489 | multivesicular body, internal vesicle lumen(GO:0097489) |
| 3.3 | 9.9 | GO:0030895 | apolipoprotein B mRNA editing enzyme complex(GO:0030895) |
| 3.1 | 15.4 | GO:0000801 | central element(GO:0000801) |
| 2.7 | 13.5 | GO:0005602 | complement component C1 complex(GO:0005602) |
| 2.6 | 29.0 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 2.5 | 35.7 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 2.4 | 9.6 | GO:0005889 | hydrogen:potassium-exchanging ATPase complex(GO:0005889) |
| 2.1 | 14.7 | GO:0097013 | phagocytic vesicle lumen(GO:0097013) |
| 2.0 | 31.3 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 1.8 | 5.3 | GO:0000806 | Y chromosome(GO:0000806) |
| 1.5 | 10.8 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 1.4 | 5.5 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
| 1.1 | 57.3 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 1.1 | 12.7 | GO:0005583 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 1.1 | 13.7 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 1.0 | 19.8 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.9 | 4.7 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.9 | 2.7 | GO:0097679 | other organism cytoplasm(GO:0097679) |
| 0.9 | 12.5 | GO:0005858 | axonemal dynein complex(GO:0005858) |
| 0.8 | 10.1 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.8 | 10.6 | GO:0001741 | XY body(GO:0001741) nuclear pericentric heterochromatin(GO:0031618) |
| 0.7 | 2.2 | GO:0034272 | phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272) |
| 0.7 | 2.9 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
| 0.7 | 12.8 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
| 0.7 | 14.8 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.7 | 11.8 | GO:0005687 | U4 snRNP(GO:0005687) |
| 0.6 | 2.5 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 0.6 | 12.9 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.6 | 18.4 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.6 | 31.4 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.6 | 0.6 | GO:0034680 | integrin alpha10-beta1 complex(GO:0034680) |
| 0.5 | 3.2 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.5 | 92.4 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.5 | 4.6 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.5 | 5.5 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.5 | 3.9 | GO:0000322 | storage vacuole(GO:0000322) |
| 0.5 | 1.5 | GO:0071020 | post-spliceosomal complex(GO:0071020) |
| 0.5 | 7.8 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.5 | 15.7 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.5 | 3.2 | GO:0031415 | NatA complex(GO:0031415) |
| 0.4 | 5.3 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.4 | 3.4 | GO:0034464 | BBSome(GO:0034464) |
| 0.4 | 1.4 | GO:0016939 | kinesin II complex(GO:0016939) |
| 0.3 | 8.6 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
| 0.3 | 28.8 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.3 | 5.0 | GO:0036020 | endolysosome membrane(GO:0036020) |
| 0.3 | 4.0 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 0.3 | 6.0 | GO:0043220 | Schmidt-Lanterman incisure(GO:0043220) |
| 0.3 | 1.5 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
| 0.3 | 11.5 | GO:0030018 | Z disc(GO:0030018) |
| 0.3 | 2.2 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.3 | 1.9 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.3 | 4.3 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.3 | 1.6 | GO:0045179 | apical cortex(GO:0045179) |
| 0.3 | 4.3 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.2 | 2.1 | GO:0005883 | neurofilament(GO:0005883) |
| 0.2 | 1.6 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.2 | 4.1 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.2 | 7.8 | GO:0002102 | podosome(GO:0002102) |
| 0.2 | 29.5 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.2 | 15.1 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.2 | 1.9 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.2 | 5.0 | GO:0071437 | invadopodium(GO:0071437) |
| 0.2 | 2.4 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.2 | 21.5 | GO:0042641 | actomyosin(GO:0042641) |
| 0.2 | 22.4 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.2 | 3.5 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.2 | 9.8 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.2 | 1.6 | GO:0016013 | syntrophin complex(GO:0016013) |
| 0.2 | 8.7 | GO:0031672 | A band(GO:0031672) |
| 0.2 | 227.4 | GO:0005615 | extracellular space(GO:0005615) |
| 0.2 | 24.2 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.1 | 5.7 | GO:0000786 | nucleosome(GO:0000786) |
| 0.1 | 12.6 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
| 0.1 | 7.6 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.1 | 2.1 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.1 | 4.3 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.1 | 3.2 | GO:0044298 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 0.1 | 4.6 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
| 0.1 | 1.2 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.1 | 9.6 | GO:0030175 | filopodium(GO:0030175) |
| 0.1 | 7.9 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.1 | 4.0 | GO:0031228 | intrinsic component of Golgi membrane(GO:0031228) |
| 0.1 | 3.5 | GO:0045095 | keratin filament(GO:0045095) |
| 0.1 | 2.7 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.1 | 13.8 | GO:0009986 | cell surface(GO:0009986) |
| 0.1 | 13.0 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.1 | 2.2 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.1 | 5.3 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.1 | 10.4 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.1 | 11.1 | GO:0042383 | sarcolemma(GO:0042383) |
| 0.1 | 1.2 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.1 | 6.0 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
| 0.1 | 6.3 | GO:0031514 | motile cilium(GO:0031514) |
| 0.1 | 1.2 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342) |
| 0.1 | 2.8 | GO:0016459 | myosin complex(GO:0016459) |
| 0.1 | 3.8 | GO:0005884 | actin filament(GO:0005884) |
| 0.1 | 1.5 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.0 | 5.7 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 52.9 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.0 | 2.1 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 26.0 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 0.0 | 1.8 | GO:0005938 | cell cortex(GO:0005938) |
| 0.0 | 0.8 | GO:0030658 | transport vesicle membrane(GO:0030658) |
| 0.0 | 0.2 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.0 | 1.5 | GO:0005923 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
| 0.0 | 1.5 | GO:0016234 | inclusion body(GO:0016234) |
| 0.0 | 1.1 | GO:0030027 | lamellipodium(GO:0030027) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.4 | 22.1 | GO:0019959 | interleukin-8 binding(GO:0019959) |
| 6.3 | 6.3 | GO:0070052 | collagen V binding(GO:0070052) |
| 4.5 | 13.6 | GO:0015199 | amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226) |
| 4.2 | 20.9 | GO:0016402 | pristanoyl-CoA oxidase activity(GO:0016402) |
| 3.6 | 25.4 | GO:0015562 | efflux transmembrane transporter activity(GO:0015562) |
| 3.5 | 10.4 | GO:0004040 | amidase activity(GO:0004040) fucose binding(GO:0042806) |
| 3.3 | 22.8 | GO:0070891 | lipoteichoic acid binding(GO:0070891) |
| 3.1 | 21.7 | GO:0031726 | CCR1 chemokine receptor binding(GO:0031726) |
| 2.9 | 14.7 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 2.9 | 14.5 | GO:0005152 | interleukin-1 receptor antagonist activity(GO:0005152) |
| 2.7 | 196.8 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 2.6 | 7.9 | GO:0036134 | thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134) |
| 2.5 | 15.1 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 2.4 | 12.1 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
| 2.4 | 21.7 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) |
| 2.4 | 7.2 | GO:0004487 | methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488) |
| 2.4 | 9.6 | GO:0008900 | hydrogen:potassium-exchanging ATPase activity(GO:0008900) |
| 2.3 | 20.9 | GO:0032190 | acrosin binding(GO:0032190) |
| 2.3 | 11.5 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
| 2.2 | 11.0 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
| 2.1 | 10.6 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 2.1 | 6.3 | GO:0016992 | lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283) |
| 2.0 | 6.1 | GO:0047273 | galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273) |
| 2.0 | 6.0 | GO:0008513 | secondary active organic cation transmembrane transporter activity(GO:0008513) |
| 1.8 | 5.5 | GO:0004917 | interleukin-7 receptor activity(GO:0004917) |
| 1.8 | 3.6 | GO:0048030 | disaccharide binding(GO:0048030) |
| 1.8 | 5.3 | GO:0046848 | hydroxyapatite binding(GO:0046848) |
| 1.8 | 7.0 | GO:0008112 | nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760) |
| 1.7 | 10.4 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 1.7 | 10.3 | GO:0003796 | lysozyme activity(GO:0003796) |
| 1.7 | 18.6 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 1.7 | 6.6 | GO:1904492 | Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493) |
| 1.6 | 6.4 | GO:0005502 | 11-cis retinal binding(GO:0005502) |
| 1.6 | 4.8 | GO:0061752 | telomeric repeat-containing RNA binding(GO:0061752) |
| 1.6 | 4.7 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
| 1.5 | 15.3 | GO:0030882 | lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884) |
| 1.4 | 4.2 | GO:0019961 | interferon binding(GO:0019961) |
| 1.3 | 4.0 | GO:0001181 | transcription factor activity, core RNA polymerase I binding(GO:0001181) |
| 1.2 | 17.4 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 1.2 | 3.6 | GO:0015234 | thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) uptake transmembrane transporter activity(GO:0015563) |
| 1.2 | 5.9 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
| 1.2 | 4.6 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 1.2 | 6.9 | GO:0030109 | HLA-B specific inhibitory MHC class I receptor activity(GO:0030109) |
| 1.2 | 4.6 | GO:0042132 | fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132) |
| 1.2 | 4.6 | GO:0004657 | proline dehydrogenase activity(GO:0004657) |
| 1.1 | 4.3 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 1.1 | 14.8 | GO:0030957 | Tat protein binding(GO:0030957) |
| 1.0 | 57.3 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 1.0 | 5.1 | GO:0033695 | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875) |
| 1.0 | 4.1 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
| 1.0 | 31.3 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 1.0 | 4.0 | GO:0018685 | alkane 1-monooxygenase activity(GO:0018685) |
| 1.0 | 3.9 | GO:0022850 | serotonin-gated cation channel activity(GO:0022850) |
| 1.0 | 16.3 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 1.0 | 5.7 | GO:0004024 | alcohol dehydrogenase activity, zinc-dependent(GO:0004024) |
| 0.9 | 10.1 | GO:0086007 | voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007) |
| 0.9 | 10.1 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) |
| 0.9 | 2.7 | GO:0005137 | interleukin-5 receptor binding(GO:0005137) |
| 0.9 | 44.5 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.9 | 3.4 | GO:0004346 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
| 0.8 | 20.3 | GO:0070403 | NAD+ binding(GO:0070403) |
| 0.8 | 5.0 | GO:0008241 | peptidyl-dipeptidase activity(GO:0008241) |
| 0.8 | 2.5 | GO:0017129 | triglyceride binding(GO:0017129) |
| 0.8 | 3.2 | GO:1990190 | peptide-glutamate-N-acetyltransferase activity(GO:1990190) |
| 0.8 | 10.3 | GO:0004745 | retinol dehydrogenase activity(GO:0004745) |
| 0.7 | 8.9 | GO:0042608 | T cell receptor binding(GO:0042608) |
| 0.7 | 2.2 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) Toll-like receptor 2 binding(GO:0035663) |
| 0.7 | 125.1 | GO:0003823 | antigen binding(GO:0003823) |
| 0.7 | 9.9 | GO:0070330 | aromatase activity(GO:0070330) |
| 0.7 | 18.3 | GO:0038187 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
| 0.7 | 36.4 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.7 | 12.5 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
| 0.7 | 3.3 | GO:0017060 | 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060) |
| 0.7 | 5.9 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.7 | 17.7 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.7 | 3.9 | GO:0017018 | myosin phosphatase activity(GO:0017018) |
| 0.7 | 7.2 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
| 0.6 | 1.9 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 0.6 | 3.2 | GO:0004995 | tachykinin receptor activity(GO:0004995) |
| 0.6 | 1.2 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
| 0.6 | 3.0 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 0.6 | 1.7 | GO:0004914 | interleukin-5 receptor activity(GO:0004914) |
| 0.6 | 4.5 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.6 | 2.8 | GO:0016427 | tRNA (cytosine) methyltransferase activity(GO:0016427) |
| 0.6 | 3.9 | GO:0047894 | flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294) |
| 0.5 | 2.7 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.5 | 1.6 | GO:0008955 | peptidoglycan glycosyltransferase activity(GO:0008955) |
| 0.5 | 8.6 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
| 0.5 | 2.7 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.5 | 4.8 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
| 0.5 | 54.4 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.5 | 2.1 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
| 0.5 | 7.7 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.5 | 8.7 | GO:0032052 | bile acid binding(GO:0032052) |
| 0.5 | 1.5 | GO:0005260 | channel-conductance-controlling ATPase activity(GO:0005260) |
| 0.5 | 2.0 | GO:0051916 | granulocyte colony-stimulating factor binding(GO:0051916) |
| 0.5 | 1.5 | GO:0000386 | second spliceosomal transesterification activity(GO:0000386) |
| 0.5 | 2.4 | GO:0030021 | extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345) |
| 0.5 | 3.2 | GO:0005353 | fructose transmembrane transporter activity(GO:0005353) |
| 0.5 | 13.5 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.4 | 2.2 | GO:0031962 | mineralocorticoid receptor binding(GO:0031962) |
| 0.4 | 11.9 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) |
| 0.4 | 2.2 | GO:0015056 | corticotrophin-releasing factor receptor activity(GO:0015056) |
| 0.4 | 1.2 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
| 0.4 | 4.3 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.4 | 11.0 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.4 | 3.8 | GO:0009374 | biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374) |
| 0.4 | 4.1 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
| 0.4 | 18.6 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.4 | 1.8 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 0.4 | 2.1 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.3 | 4.5 | GO:0001087 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.3 | 6.6 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
| 0.3 | 4.9 | GO:0015245 | fatty acid transporter activity(GO:0015245) very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.3 | 1.4 | GO:0004979 | beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047) |
| 0.3 | 1.7 | GO:0004815 | aspartate-tRNA ligase activity(GO:0004815) |
| 0.3 | 2.4 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
| 0.3 | 4.3 | GO:0043855 | intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855) |
| 0.3 | 3.5 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.3 | 25.8 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.3 | 5.6 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.3 | 3.9 | GO:1902282 | voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282) |
| 0.3 | 0.6 | GO:0098639 | collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 0.3 | 6.8 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.3 | 14.8 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.3 | 7.4 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.3 | 1.6 | GO:0052654 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.3 | 56.9 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.3 | 4.1 | GO:0005522 | profilin binding(GO:0005522) |
| 0.3 | 2.0 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
| 0.3 | 1.0 | GO:0016635 | oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635) |
| 0.2 | 1.2 | GO:0033857 | diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 0.2 | 23.0 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.2 | 3.7 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.2 | 2.1 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.2 | 1.2 | GO:0097199 | cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199) |
| 0.2 | 0.7 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.2 | 4.5 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.2 | 5.2 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.2 | 0.6 | GO:0033149 | FFAT motif binding(GO:0033149) |
| 0.2 | 10.0 | GO:0033558 | histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558) |
| 0.2 | 6.1 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.2 | 31.4 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.2 | 7.2 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.2 | 1.0 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
| 0.2 | 5.6 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.2 | 1.5 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
| 0.2 | 2.7 | GO:0034483 | heparan sulfate sulfotransferase activity(GO:0034483) |
| 0.2 | 6.5 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.2 | 3.6 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.2 | 9.3 | GO:0001099 | basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099) |
| 0.2 | 0.9 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.2 | 7.1 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.2 | 27.5 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.2 | 13.7 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.2 | 2.2 | GO:0015377 | cation:chloride symporter activity(GO:0015377) |
| 0.2 | 0.5 | GO:0004947 | bradykinin receptor activity(GO:0004947) |
| 0.1 | 2.4 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.1 | 1.9 | GO:0001013 | RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164) |
| 0.1 | 9.6 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.1 | 3.3 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
| 0.1 | 3.1 | GO:0005319 | lipid transporter activity(GO:0005319) |
| 0.1 | 5.6 | GO:0015144 | carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476) |
| 0.1 | 2.0 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.1 | 3.3 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.1 | 6.0 | GO:0008022 | protein C-terminus binding(GO:0008022) |
| 0.1 | 1.7 | GO:0005217 | intracellular ligand-gated ion channel activity(GO:0005217) calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604) |
| 0.1 | 1.6 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.1 | 1.9 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.1 | 2.2 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
| 0.1 | 5.9 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.1 | 3.7 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.1 | 0.8 | GO:0070915 | lysophosphatidic acid receptor activity(GO:0070915) |
| 0.1 | 0.5 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.1 | 0.6 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.1 | 5.3 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.1 | 2.1 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.1 | 0.9 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.1 | 7.2 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.1 | 2.2 | GO:0016303 | 1-phosphatidylinositol-3-kinase activity(GO:0016303) |
| 0.1 | 1.0 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.1 | 1.8 | GO:0001848 | complement binding(GO:0001848) |
| 0.1 | 1.3 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.1 | 1.1 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.1 | 16.3 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.1 | 10.3 | GO:0004713 | protein tyrosine kinase activity(GO:0004713) |
| 0.1 | 4.4 | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553) |
| 0.1 | 6.4 | GO:0019210 | kinase inhibitor activity(GO:0019210) |
| 0.1 | 2.6 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.1 | 2.4 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.1 | 0.9 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.1 | 4.9 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
| 0.1 | 1.4 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.1 | 14.2 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.1 | 2.1 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.1 | 1.6 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.1 | 1.8 | GO:0004519 | endonuclease activity(GO:0004519) |
| 0.0 | 0.1 | GO:0099580 | ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580) |
| 0.0 | 4.7 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
| 0.0 | 0.7 | GO:0004062 | aryl sulfotransferase activity(GO:0004062) |
| 0.0 | 28.7 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.0 | 1.2 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
| 0.0 | 2.7 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 3.2 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 2.9 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.0 | 5.7 | GO:0042393 | histone binding(GO:0042393) |
| 0.0 | 1.2 | GO:0008235 | metalloexopeptidase activity(GO:0008235) |
| 0.0 | 0.4 | GO:0016423 | tRNA (guanine) methyltransferase activity(GO:0016423) |
| 0.0 | 0.2 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.0 | 0.3 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.0 | 3.5 | GO:0005057 | receptor signaling protein activity(GO:0005057) |
| 0.0 | 0.4 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.0 | 1.5 | GO:0019838 | growth factor binding(GO:0019838) |
| 0.0 | 3.0 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.7 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.7 | 207.1 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.8 | 0.8 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.6 | 9.1 | ST TYPE I INTERFERON PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
| 0.6 | 10.4 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.6 | 21.7 | PID S1P S1P3 PATHWAY | S1P3 pathway |
| 0.5 | 133.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.5 | 26.7 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.5 | 11.1 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.4 | 10.3 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.4 | 2.7 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.4 | 11.0 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.4 | 21.2 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.4 | 63.9 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.4 | 6.5 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.3 | 18.0 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.3 | 4.4 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.3 | 4.2 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.2 | 10.2 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.2 | 4.3 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.2 | 5.6 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 0.2 | 10.8 | PID MYC PATHWAY | C-MYC pathway |
| 0.2 | 10.1 | SIG PIP3 SIGNALING IN B LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.2 | 2.5 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.2 | 1.1 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.2 | 6.5 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
| 0.2 | 17.0 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.2 | 3.1 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 0.2 | 3.5 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.2 | 14.9 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.2 | 5.9 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.2 | 7.2 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.2 | 5.1 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.1 | 2.8 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.1 | 4.1 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.1 | 3.3 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.1 | 15.0 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 13.7 | PID E2F PATHWAY | E2F transcription factor network |
| 0.1 | 14.2 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
| 0.1 | 6.3 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.1 | 7.4 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.1 | 10.7 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 4.7 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.1 | 1.8 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.1 | 2.2 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.1 | 5.8 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.1 | 2.4 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.1 | 1.9 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.1 | 6.0 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.1 | 2.4 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.1 | 2.4 | PID FGF PATHWAY | FGF signaling pathway |
| 0.1 | 0.6 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.1 | 16.6 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 2.1 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.1 | 2.9 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.1 | 3.8 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 1.2 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.0 | 0.8 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.0 | 2.1 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 1.4 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.0 | 1.2 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.0 | 1.2 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.0 | 5.8 | NABA MATRISOME ASSOCIATED | Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors |
| 0.0 | 0.5 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.5 | 203.5 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 4.3 | 21.7 | REACTOME BINDING AND ENTRY OF HIV VIRION | Genes involved in Binding and entry of HIV virion |
| 2.2 | 44.4 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 1.3 | 29.0 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 1.2 | 13.5 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 1.1 | 13.7 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 1.1 | 16.3 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.9 | 11.7 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.9 | 44.5 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.7 | 8.4 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.6 | 23.4 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.5 | 17.7 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.5 | 21.0 | REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
| 0.5 | 13.2 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.5 | 15.2 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.5 | 8.4 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.4 | 9.1 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.4 | 11.4 | REACTOME SHC1 EVENTS IN EGFR SIGNALING | Genes involved in SHC1 events in EGFR signaling |
| 0.4 | 5.0 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.4 | 12.7 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.4 | 23.7 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.4 | 24.2 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.4 | 8.4 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.3 | 26.0 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.3 | 10.4 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.3 | 5.1 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.3 | 17.2 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.3 | 12.7 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.2 | 13.9 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.2 | 12.4 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.2 | 4.7 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.2 | 11.7 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.2 | 3.8 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.2 | 2.2 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.2 | 7.6 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.2 | 4.4 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.2 | 9.6 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.2 | 6.7 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.2 | 11.8 | REACTOME NUCLEAR SIGNALING BY ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.2 | 2.4 | REACTOME FGFR4 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
| 0.2 | 1.8 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.2 | 4.6 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.2 | 15.0 | REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | Genes involved in Cell surface interactions at the vascular wall |
| 0.2 | 5.0 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.2 | 6.6 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.2 | 2.9 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.2 | 3.2 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.1 | 15.4 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.1 | 8.9 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.1 | 1.6 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.1 | 2.5 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.1 | 4.0 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.1 | 5.9 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.1 | 2.5 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.1 | 9.5 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.1 | 2.2 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.1 | 3.6 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.1 | 2.9 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 0.9 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.1 | 4.6 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.1 | 3.9 | REACTOME ION CHANNEL TRANSPORT | Genes involved in Ion channel transport |
| 0.1 | 12.0 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.1 | 1.0 | REACTOME ARMS MEDIATED ACTIVATION | Genes involved in ARMS-mediated activation |
| 0.1 | 4.5 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.1 | 2.1 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.1 | 2.2 | REACTOME CA DEPENDENT EVENTS | Genes involved in Ca-dependent events |
| 0.1 | 9.0 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 29.3 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.1 | 2.7 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.1 | 2.1 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.1 | 2.1 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.1 | 2.0 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.1 | 3.2 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.1 | 2.4 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.1 | 1.1 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.1 | 7.5 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
| 0.1 | 3.0 | REACTOME PHASE II CONJUGATION | Genes involved in Phase II conjugation |
| 0.1 | 2.1 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.1 | 1.6 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 2.2 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 0.4 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.0 | 3.6 | REACTOME G ALPHA S SIGNALLING EVENTS | Genes involved in G alpha (s) signalling events |
| 0.0 | 0.1 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.0 | 0.4 | REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 | Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1 |
| 0.0 | 1.0 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.0 | 2.2 | REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE | Genes involved in MyD88:Mal cascade initiated on plasma membrane |
| 0.0 | 0.3 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.0 | 0.6 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.6 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 0.3 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |