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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for KLF12

Z-value: 0.84

Motif logo

Transcription factors associated with KLF12

Gene Symbol Gene ID Gene Info
ENSG00000118922.12 Kruppel like factor 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF12hg19_v2_chr13_-_74708372_74708409-0.342.5e-07Click!

Activity profile of KLF12 motif

Sorted Z-values of KLF12 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_89402148 23.04 ENST00000560601.1
aggrecan
chrX_+_23682379 16.47 ENST00000379349.1
peroxiredoxin 4
chrX_+_49028265 11.17 ENST00000376322.3
ENST00000376327.5
proteolipid protein 2 (colonic epithelium-enriched)
chr12_-_56120838 10.75 ENST00000548160.1
CD63 molecule
chr1_+_155178481 10.68 ENST00000368376.3
metaxin 1
chr12_-_53012343 10.19 ENST00000305748.3
keratin 73
chr11_-_64013288 9.88 ENST00000542235.1
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr19_+_13051206 9.51 ENST00000586760.1
calreticulin
chr15_+_64428529 9.39 ENST00000560861.1
sorting nexin 1
chr12_+_53848549 9.10 ENST00000439930.3
ENST00000548933.1
ENST00000562264.1
poly(rC) binding protein 2
chr8_-_71519889 8.72 ENST00000521425.1
translocation associated membrane protein 1
chr1_+_155178518 8.19 ENST00000316721.4
metaxin 1
chr15_-_34394119 8.17 ENST00000256545.4
ER membrane protein complex subunit 7
chr12_-_109125285 7.94 ENST00000552871.1
ENST00000261401.3
coronin, actin binding protein, 1C
chr12_-_120907374 7.85 ENST00000550458.1
serine/arginine-rich splicing factor 9
chr7_+_65552756 7.66 ENST00000450043.1
AC068533.7
chr10_+_51371390 7.64 ENST00000478381.1
ENST00000451577.2
ENST00000374098.2
ENST00000374097.2
translocase of inner mitochondrial membrane 23 homolog B (yeast)
chr17_+_27071002 7.48 ENST00000262395.5
ENST00000422344.1
ENST00000444415.3
ENST00000262396.6
TNF receptor-associated factor 4
chr17_-_38978847 7.46 ENST00000269576.5
keratin 10
chr17_-_79827808 7.38 ENST00000580685.1
Rho GDP dissociation inhibitor (GDI) alpha
chr1_+_153750622 7.34 ENST00000532853.1
solute carrier family 27 (fatty acid transporter), member 3
chr12_-_56120865 7.25 ENST00000548898.1
ENST00000552067.1
CD63 molecule
chr2_-_32236002 7.17 ENST00000404530.1
mediator of cell motility 1
chr15_-_64673630 7.14 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
chr15_-_34394008 6.88 ENST00000527822.1
ENST00000528949.1
ER membrane protein complex subunit 7
chr15_-_75230368 6.61 ENST00000564811.1
ENST00000562233.1
ENST00000567270.1
ENST00000568783.1
cytochrome c oxidase subunit Va
chr12_-_120907459 6.57 ENST00000229390.3
serine/arginine-rich splicing factor 9
chr9_-_127952032 6.51 ENST00000456642.1
ENST00000373546.3
ENST00000373547.4
protein phosphatase 6, catalytic subunit
chr1_+_32687971 6.41 ENST00000373586.1
eukaryotic translation initiation factor 3, subunit I
chr10_+_81272287 6.33 ENST00000520547.2
eukaryotic translation initiation factor 5A-like 1
chr14_+_24605361 6.21 ENST00000206451.6
ENST00000559123.1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr14_-_106174960 6.10 ENST00000390547.2
immunoglobulin heavy constant alpha 1
chr11_-_46142948 6.09 ENST00000257821.4
PHD finger protein 21A
chr16_+_29819096 5.93 ENST00000568411.1
ENST00000563012.1
ENST00000562557.1
MYC-associated zinc finger protein (purine-binding transcription factor)
chr13_-_46716969 5.91 ENST00000435666.2
lymphocyte cytosolic protein 1 (L-plastin)
chr2_-_89459813 5.90 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr17_+_7210898 5.90 ENST00000572815.1
eukaryotic translation initiation factor 5A
chr9_+_131445928 5.86 ENST00000372692.4
SET nuclear oncogene
chr5_-_179227540 5.70 ENST00000520875.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr8_-_101962777 5.64 ENST00000395951.3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr1_+_24117693 5.62 ENST00000374503.3
ENST00000374502.3
lysophospholipase II
chr20_-_49547731 5.62 ENST00000396029.3
activity-dependent neuroprotector homeobox
chr9_-_127952187 5.46 ENST00000451402.1
ENST00000415905.1
protein phosphatase 6, catalytic subunit
chr9_-_139371533 5.43 ENST00000290037.6
ENST00000431893.2
ENST00000371706.3
SEC16 homolog A (S. cerevisiae)
chr1_+_26798955 5.37 ENST00000361427.5
high mobility group nucleosomal binding domain 2
chr12_-_56122220 5.28 ENST00000552692.1
CD63 molecule
chr2_-_153573887 5.27 ENST00000493468.2
ENST00000545856.1
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr17_-_79818354 5.27 ENST00000576541.1
ENST00000576380.1
ENST00000571617.1
ENST00000576052.1
ENST00000576390.1
ENST00000573778.2
ENST00000439918.2
ENST00000574914.1
ENST00000331483.4
prolyl 4-hydroxylase, beta polypeptide
chr19_-_47349395 5.16 ENST00000597020.1
adaptor-related protein complex 2, sigma 1 subunit
chr2_-_220435963 5.14 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
obscurin-like 1
chr7_-_140179276 5.10 ENST00000443720.2
ENST00000255977.2
makorin ring finger protein 1
chr10_-_51623203 5.09 ENST00000444743.1
ENST00000374065.3
ENST00000374064.3
ENST00000260867.4
translocase of inner mitochondrial membrane 23 homolog (yeast)
chr12_-_56122124 5.04 ENST00000552754.1
CD63 molecule
chr15_-_75230478 5.02 ENST00000322347.6
cytochrome c oxidase subunit Va
chr9_-_34637718 4.99 ENST00000378892.1
ENST00000277010.4
sigma non-opioid intracellular receptor 1
chrX_-_107334750 4.97 ENST00000340200.5
ENST00000372296.1
ENST00000372295.1
ENST00000361815.5
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr7_-_65447192 4.88 ENST00000421103.1
ENST00000345660.6
ENST00000304895.4
glucuronidase, beta
chr16_+_103816 4.87 ENST00000383018.3
ENST00000417493.1
small nuclear ribonucleoprotein 25kDa (U11/U12)
chr19_+_39214797 4.83 ENST00000440400.1
actinin, alpha 4
chr2_+_90139056 4.80 ENST00000492446.1
immunoglobulin kappa variable 1D-16
chr12_-_56121580 4.77 ENST00000550776.1
CD63 molecule
chrX_-_107334790 4.70 ENST00000217958.3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr12_+_53848505 4.64 ENST00000552819.1
ENST00000455667.3
poly(rC) binding protein 2
chr17_-_47841485 4.61 ENST00000506156.1
ENST00000240364.2
family with sequence similarity 117, member A
chr16_+_29818857 4.59 ENST00000567444.1
MYC-associated zinc finger protein (purine-binding transcription factor)
chr16_+_29819372 4.58 ENST00000568544.1
ENST00000569978.1
MYC-associated zinc finger protein (purine-binding transcription factor)
chr16_-_103572 4.58 ENST00000293860.5
polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
chrX_-_129299638 4.51 ENST00000535724.1
ENST00000346424.2
apoptosis-inducing factor, mitochondrion-associated, 1
chr2_-_89568263 4.51 ENST00000473726.1
immunoglobulin kappa variable 1-33
chr14_-_106054659 4.51 ENST00000390539.2
immunoglobulin heavy constant alpha 2 (A2m marker)
chrX_-_129299847 4.50 ENST00000319908.3
ENST00000287295.3
apoptosis-inducing factor, mitochondrion-associated, 1
chr5_+_34656331 4.40 ENST00000265109.3
retinoic acid induced 14
chr11_-_1643368 4.38 ENST00000399682.1
keratin associated protein 5-4
chr1_+_156084461 4.37 ENST00000347559.2
ENST00000361308.4
ENST00000368300.4
ENST00000368299.3
lamin A/C
chr1_-_244615425 4.35 ENST00000366535.3
adenylosuccinate synthase
chr16_+_29819446 4.35 ENST00000568282.1
MYC-associated zinc finger protein (purine-binding transcription factor)
chr14_+_75348592 4.32 ENST00000334220.4
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr17_+_8191815 4.31 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RAN guanine nucleotide release factor
chr10_-_103880209 4.29 ENST00000425280.1
LIM domain binding 1
chr7_+_107220660 4.28 ENST00000465919.1
ENST00000445771.2
ENST00000479917.1
ENST00000421217.1
ENST00000457837.1
B-cell receptor-associated protein 29
chr1_-_153538011 4.27 ENST00000368707.4
S100 calcium binding protein A2
chr7_+_107220899 4.26 ENST00000379117.2
ENST00000473124.1
B-cell receptor-associated protein 29
chr2_-_89399845 4.26 ENST00000479981.1
immunoglobulin kappa variable 1-16
chr2_+_89952792 4.25 ENST00000390265.2
immunoglobulin kappa variable 1D-33
chr19_+_19303720 4.24 ENST00000392324.4
regulatory factor X-associated ankyrin-containing protein
chr4_+_184426147 4.23 ENST00000302327.3
inhibitor of growth family, member 2
chr19_-_39330818 4.17 ENST00000594769.1
ENST00000602021.1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial
chr17_+_57784997 4.16 ENST00000537567.1
ENST00000539763.1
ENST00000587945.1
ENST00000536180.1
ENST00000589823.2
ENST00000592106.1
ENST00000591315.1
ENST00000545362.1
vacuole membrane protein 1
chr17_-_76899275 4.01 ENST00000322630.2
ENST00000586713.1
Protein DDC8 homolog
chr16_-_20911641 3.96 ENST00000564349.1
ENST00000324344.4
ERI1 exoribonuclease family member 2
DCN1, defective in cullin neddylation 1, domain containing 3
chrX_+_47082408 3.95 ENST00000518022.1
ENST00000276052.6
cyclin-dependent kinase 16
chr5_+_34656569 3.92 ENST00000428746.2
retinoic acid induced 14
chr12_+_7060432 3.91 ENST00000318974.9
ENST00000456013.1
protein tyrosine phosphatase, non-receptor type 6
chr17_+_7155343 3.89 ENST00000573513.1
ENST00000354429.2
ENST00000574255.1
ENST00000396627.2
ENST00000356683.2
elongator acetyltransferase complex subunit 5
chr11_-_73689037 3.89 ENST00000544615.1
uncoupling protein 2 (mitochondrial, proton carrier)
chr7_+_2394445 3.82 ENST00000360876.4
ENST00000413917.1
ENST00000397011.2
eukaryotic translation initiation factor 3, subunit B
chr15_+_74218787 3.81 ENST00000261921.7
lysyl oxidase-like 1
chr2_+_99953816 3.79 ENST00000289371.6
eukaryotic translation initiation factor 5B
chr19_+_19303572 3.74 ENST00000407360.3
ENST00000540981.1
regulatory factor X-associated ankyrin-containing protein
chr2_-_153573965 3.71 ENST00000448428.1
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr17_-_57784755 3.70 ENST00000537860.1
ENST00000393038.2
ENST00000409433.2
peptidyl-tRNA hydrolase 2
chr12_-_46766577 3.67 ENST00000256689.5
solute carrier family 38, member 2
chr1_-_32403903 3.61 ENST00000344035.6
ENST00000356536.3
protein tyrosine phosphatase type IVA, member 2
chr20_-_49547910 3.56 ENST00000396032.3
activity-dependent neuroprotector homeobox
chr21_-_38445011 3.54 ENST00000464265.1
ENST00000399102.1
phosphatidylinositol glycan anchor biosynthesis, class P
chr12_+_32832134 3.47 ENST00000452533.2
dynamin 1-like
chr7_-_140178726 3.47 ENST00000480552.1
makorin ring finger protein 1
chr3_+_184037466 3.45 ENST00000441154.1
eukaryotic translation initiation factor 4 gamma, 1
chr17_+_57784826 3.41 ENST00000262291.4
vacuole membrane protein 1
chr19_-_2050852 3.38 ENST00000541165.1
ENST00000591601.1
MAP kinase interacting serine/threonine kinase 2
chr22_+_47016277 3.35 ENST00000406902.1
GRAM domain containing 4
chr1_+_24117627 3.34 ENST00000400061.1
lysophospholipase II
chr3_-_52713729 3.34 ENST00000296302.7
ENST00000356770.4
ENST00000337303.4
ENST00000409057.1
ENST00000410007.1
ENST00000409114.3
ENST00000409767.1
ENST00000423351.1
polybromo 1
chr17_+_7210921 3.28 ENST00000573542.1
eukaryotic translation initiation factor 5A
chr21_-_38445297 3.26 ENST00000430792.1
ENST00000399103.1
phosphatidylinositol glycan anchor biosynthesis, class P
chr12_+_120907622 3.24 ENST00000392509.2
ENST00000549649.1
ENST00000548342.1
dynein, light chain, LC8-type 1
chr16_-_67969888 3.23 ENST00000574576.2
proteasome (prosome, macropain) subunit, beta type, 10
chr20_-_1373682 3.23 ENST00000381724.3
FK506 binding protein 1A, 12kDa
chr10_-_16859361 3.22 ENST00000377921.3
Ras suppressor protein 1
chr2_-_111291587 3.20 ENST00000437167.1
RANBP2-like and GRIP domain containing 6
chr3_+_49058444 3.19 ENST00000326925.6
ENST00000395458.2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr6_-_114292284 3.16 ENST00000520895.1
ENST00000521163.1
ENST00000524334.1
ENST00000368632.2
ENST00000398283.2
histone deacetylase 2
chr11_-_67120974 3.14 ENST00000539074.1
ENST00000312419.3
polymerase (DNA-directed), delta 4, accessory subunit
chr16_+_75256507 3.13 ENST00000495583.1
chymotrypsinogen B1
chr10_+_21823079 3.13 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr11_+_118889456 3.11 ENST00000528230.1
ENST00000525303.1
ENST00000434101.2
ENST00000359005.4
ENST00000533058.1
trafficking protein particle complex 4
chr2_-_27593180 3.09 ENST00000493344.2
ENST00000445933.2
eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
chr6_-_114292449 3.08 ENST00000519065.1
histone deacetylase 2
chr17_-_36891830 3.06 ENST00000578487.1
polycomb group ring finger 2
chr12_+_32832203 3.02 ENST00000553257.1
ENST00000549701.1
ENST00000358214.5
ENST00000266481.6
ENST00000551476.1
ENST00000550154.1
ENST00000547312.1
ENST00000414834.2
ENST00000381000.4
ENST00000548750.1
dynamin 1-like
chr3_-_52567792 2.99 ENST00000307092.4
ENST00000422318.2
ENST00000459839.1
5'-nucleotidase domain containing 2
chr3_+_148508845 2.94 ENST00000491148.1
carboxypeptidase B1 (tissue)
chr9_-_34637806 2.92 ENST00000477726.1
sigma non-opioid intracellular receptor 1
chr5_+_137688285 2.91 ENST00000314358.5
lysine (K)-specific demethylase 3B
chr14_+_102276209 2.86 ENST00000445439.3
ENST00000334743.5
ENST00000557095.1
protein phosphatase 2, regulatory subunit B', gamma
chr1_-_202777535 2.86 ENST00000367264.2
lysine (K)-specific demethylase 5B
chr6_+_52535878 2.84 ENST00000211314.4
transmembrane protein 14A
chrX_+_152953505 2.84 ENST00000253122.5
solute carrier family 6 (neurotransmitter transporter), member 8
chr16_+_85646891 2.76 ENST00000393243.1
Gse1 coiled-coil protein
chr22_-_39268308 2.72 ENST00000407418.3
chromobox homolog 6
chr6_-_111804393 2.69 ENST00000368802.3
ENST00000368805.1
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr22_+_38093005 2.69 ENST00000406386.3
TRIO and F-actin binding protein
chr15_-_64673665 2.65 ENST00000300035.4
KIAA0101
chr6_+_150070857 2.60 ENST00000544496.1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr17_-_7154984 2.59 ENST00000574322.1
CTD nuclear envelope phosphatase 1
chr2_+_89901292 2.58 ENST00000448155.2
immunoglobulin kappa variable 1D-39
chr2_-_89340242 2.58 ENST00000480492.1
immunoglobulin kappa variable 1-12
chr17_-_72864739 2.56 ENST00000579893.1
ENST00000544854.1
ferredoxin reductase
chr3_-_148804275 2.49 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
helicase-like transcription factor
chr18_+_19749386 2.47 ENST00000269216.3
GATA binding protein 6
chr2_+_90458201 2.47 ENST00000603238.1
Uncharacterized protein
chr1_-_31538517 2.47 ENST00000440538.2
ENST00000423018.2
ENST00000424085.2
ENST00000426105.2
ENST00000257075.5
ENST00000373747.3
ENST00000525843.1
ENST00000373742.2
pumilio RNA-binding family member 1
chr11_+_66360665 2.46 ENST00000310190.4
copper chaperone for superoxide dismutase
chrX_+_48644962 2.45 ENST00000376670.3
ENST00000376665.3
GATA binding protein 1 (globin transcription factor 1)
chr16_-_70729496 2.41 ENST00000567648.1
Vac14 homolog (S. cerevisiae)
chr19_-_8386238 2.38 ENST00000301457.2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
chr1_-_212965104 2.35 ENST00000422588.2
ENST00000366975.6
ENST00000366977.3
ENST00000366976.1
NSL1, MIS12 kinetochore complex component
chr2_+_89999259 2.32 ENST00000558026.1
immunoglobulin kappa variable 2D-28
chr16_+_31044413 2.30 ENST00000394998.1
syntaxin 4
chr1_+_116915855 2.30 ENST00000295598.5
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr1_-_6259641 2.29 ENST00000234875.4
ribosomal protein L22
chr7_+_142458507 2.28 ENST00000492062.1
protease, serine, 1 (trypsin 1)
chr2_-_89247338 2.27 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr16_+_30194916 2.26 ENST00000570045.1
ENST00000565497.1
ENST00000570244.1
coronin, actin binding protein, 1A
chr5_+_74633036 2.25 ENST00000343975.5
3-hydroxy-3-methylglutaryl-CoA reductase
chr7_+_100273736 2.25 ENST00000412215.1
ENST00000393924.1
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr17_-_8534031 2.21 ENST00000411957.1
ENST00000396239.1
ENST00000379980.4
myosin, heavy chain 10, non-muscle
chr16_-_67978016 2.19 ENST00000264005.5
lecithin-cholesterol acyltransferase
chr3_+_130569429 2.14 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATPase, Ca++ transporting, type 2C, member 1
chr10_-_27149792 2.12 ENST00000376140.3
ENST00000376170.4
abl-interactor 1
chr3_+_33840050 2.10 ENST00000457054.2
ENST00000413073.1
programmed cell death 6 interacting protein
chr17_+_80477571 2.10 ENST00000335255.5
forkhead box K2
chr17_-_8534067 2.07 ENST00000360416.3
ENST00000269243.4
myosin, heavy chain 10, non-muscle
chr16_-_29875057 2.06 ENST00000219789.6
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr3_+_193853927 2.05 ENST00000232424.3
hes family bHLH transcription factor 1
chr14_-_75530693 1.98 ENST00000555135.1
ENST00000357971.3
ENST00000553302.1
ENST00000555694.1
ENST00000238618.3
acylphosphatase 1, erythrocyte (common) type
chr2_-_47168906 1.98 ENST00000444761.2
ENST00000409147.1
multiple coagulation factor deficiency 2
chr1_-_155211017 1.97 ENST00000536770.1
ENST00000368373.3
glucosidase, beta, acid
chr17_+_7487146 1.95 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
mannose-P-dolichol utilization defect 1
chr1_-_47655686 1.95 ENST00000294338.2
PDZK1 interacting protein 1
chrX_-_10544942 1.92 ENST00000380779.1
midline 1 (Opitz/BBB syndrome)
chr15_-_23034322 1.90 ENST00000539711.2
ENST00000560039.1
ENST00000398013.3
ENST00000337451.3
ENST00000359727.4
ENST00000398014.2
non imprinted in Prader-Willi/Angelman syndrome 2
chr10_-_27149851 1.87 ENST00000376142.2
ENST00000359188.4
ENST00000376139.2
ENST00000376160.1
abl-interactor 1
chr22_-_39268192 1.87 ENST00000216083.6
chromobox homolog 6
chr9_-_117853297 1.87 ENST00000542877.1
ENST00000537320.1
ENST00000341037.4
tenascin C
chr5_+_52776228 1.79 ENST00000256759.3
follistatin
chr6_-_30640811 1.78 ENST00000376442.3
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr1_-_114355083 1.78 ENST00000261441.5
round spermatid basic protein 1
chr2_+_234104079 1.78 ENST00000417661.1
inositol polyphosphate-5-phosphatase, 145kDa
chr16_+_85646763 1.77 ENST00000411612.1
ENST00000253458.7
Gse1 coiled-coil protein
chr6_+_35995531 1.76 ENST00000229794.4
mitogen-activated protein kinase 14
chr17_+_7211280 1.75 ENST00000419711.2
ENST00000571955.1
ENST00000573714.1
eukaryotic translation initiation factor 5A
chr17_-_27418537 1.74 ENST00000408971.2
TGFB1-induced anti-apoptotic factor 1
chr10_-_27149904 1.73 ENST00000376166.1
ENST00000376138.3
ENST00000355394.4
ENST00000346832.5
ENST00000376134.3
ENST00000376137.4
ENST00000536334.1
ENST00000490841.2
abl-interactor 1
chr17_+_4618734 1.68 ENST00000571206.1
arrestin, beta 2
chr11_-_102401469 1.67 ENST00000260227.4
matrix metallopeptidase 7 (matrilysin, uterine)
chr2_+_46769798 1.65 ENST00000238738.4
ras homolog family member Q
chr5_+_74632993 1.65 ENST00000287936.4
3-hydroxy-3-methylglutaryl-CoA reductase
chr1_+_214161272 1.65 ENST00000498508.2
ENST00000366958.4
prospero homeobox 1
chr4_-_185570590 1.65 ENST00000517513.1
ENST00000447121.2
ENST00000393588.4
ENST00000308394.4
ENST00000523916.1
caspase 3, apoptosis-related cysteine peptidase

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 16.5 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
2.5 33.1 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
2.3 18.8 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
2.2 15.5 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
1.9 9.7 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
1.8 9.0 GO:0002084 protein depalmitoylation(GO:0002084)
1.6 4.8 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
1.6 9.5 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
1.5 4.4 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
1.4 4.3 GO:0019474 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
1.4 4.3 GO:0021678 fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
1.3 9.2 GO:0033484 nitric oxide homeostasis(GO:0033484)
1.2 6.2 GO:0061198 fungiform papilla formation(GO:0061198)
1.2 4.9 GO:0033277 abortive mitotic cell cycle(GO:0033277)
1.2 3.6 GO:1902568 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
1.2 23.0 GO:0042340 keratan sulfate catabolic process(GO:0042340)
1.1 4.3 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
1.1 2.1 GO:2000977 regulation of forebrain neuron differentiation(GO:2000977)
1.1 10.6 GO:0060267 positive regulation of respiratory burst(GO:0060267)
1.0 17.6 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
1.0 2.0 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
1.0 2.9 GO:2000861 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.9 4.4 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.9 8.5 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.8 12.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.8 4.2 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.8 2.5 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.8 2.5 GO:0015680 intracellular copper ion transport(GO:0015680)
0.8 2.5 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.8 7.9 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.7 4.3 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.7 2.1 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.7 9.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.7 1.3 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.7 5.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.6 7.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.6 1.9 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.6 3.7 GO:0032328 alanine transport(GO:0032328)
0.6 1.8 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.6 2.3 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.6 11.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.5 2.2 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.5 2.7 GO:0030047 actin modification(GO:0030047)
0.5 2.6 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.5 2.0 GO:1904457 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.5 3.9 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.5 3.9 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.5 14.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.5 4.1 GO:0030091 protein repair(GO:0030091)
0.4 2.6 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.4 1.2 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.4 5.8 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.4 5.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.4 3.5 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.4 5.6 GO:0090168 Golgi reassembly(GO:0090168)
0.4 5.9 GO:0051639 actin filament network formation(GO:0051639)
0.4 2.9 GO:0072718 response to cisplatin(GO:0072718)
0.3 1.4 GO:0060263 regulation of respiratory burst(GO:0060263)
0.3 6.8 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.3 3.7 GO:2000210 positive regulation of anoikis(GO:2000210)
0.3 1.7 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.3 1.3 GO:0048496 maintenance of organ identity(GO:0048496)
0.3 2.3 GO:0031947 negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of steroid hormone biosynthetic process(GO:0090032) response to glycoside(GO:1903416)
0.3 5.7 GO:0035855 megakaryocyte development(GO:0035855)
0.3 1.6 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.3 3.2 GO:0035721 intraciliary retrograde transport(GO:0035721) positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.3 1.5 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.3 5.2 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.3 7.2 GO:0006337 nucleosome disassembly(GO:0006337)
0.3 1.6 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.3 1.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.3 13.0 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.3 2.8 GO:0006600 creatine metabolic process(GO:0006600)
0.2 19.4 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.2 4.0 GO:0045116 response to UV-C(GO:0010225) protein neddylation(GO:0045116)
0.2 1.9 GO:0015693 magnesium ion transport(GO:0015693)
0.2 4.4 GO:0060347 heart trabecula formation(GO:0060347)
0.2 4.6 GO:0006379 mRNA cleavage(GO:0006379)
0.2 1.5 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.2 1.5 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.2 1.5 GO:2001268 positive regulation of keratinocyte migration(GO:0051549) negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.2 7.4 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.2 29.7 GO:0030449 regulation of complement activation(GO:0030449)
0.2 5.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.2 1.6 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.2 17.1 GO:0048207 vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.2 1.4 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.2 5.7 GO:0006491 N-glycan processing(GO:0006491)
0.2 4.9 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.2 2.9 GO:1990845 adaptive thermogenesis(GO:1990845)
0.2 2.9 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.2 1.3 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.2 1.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.2 3.4 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.2 1.0 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.2 0.8 GO:0016240 autophagosome docking(GO:0016240)
0.2 1.3 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.2 23.4 GO:0031424 keratinization(GO:0031424)
0.2 0.6 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1 1.9 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 3.9 GO:0030252 growth hormone secretion(GO:0030252)
0.1 0.5 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 0.4 GO:0035989 tendon development(GO:0035989)
0.1 0.6 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.1 8.3 GO:0006301 postreplication repair(GO:0006301)
0.1 1.2 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.1 1.8 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.1 2.0 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 2.1 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.2 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.1 1.7 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.1 8.0 GO:0032465 regulation of cytokinesis(GO:0032465)
0.1 1.1 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.1 5.4 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.1 11.7 GO:0006413 translational initiation(GO:0006413)
0.1 1.1 GO:0006939 smooth muscle contraction(GO:0006939)
0.1 9.4 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.1 0.3 GO:0035993 subthalamic nucleus development(GO:0021763) deltoid tuberosity development(GO:0035993) prolactin secreting cell differentiation(GO:0060127) left lung development(GO:0060459) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578) cell proliferation involved in outflow tract morphogenesis(GO:0061325)
0.1 0.3 GO:0035565 regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623)
0.1 0.5 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.1 11.5 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.1 0.7 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 5.6 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.7 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 1.4 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.1 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 0.8 GO:0060346 bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.1 0.8 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.6 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.1 9.3 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.1 2.1 GO:0090383 phagosome acidification(GO:0090383)
0.1 0.9 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 7.3 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.1 0.3 GO:0042476 odontogenesis(GO:0042476)
0.0 2.5 GO:0035904 aorta development(GO:0035904)
0.0 1.7 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0 0.8 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.9 GO:0002717 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 5.9 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.3 GO:0070535 negative regulation of histone ubiquitination(GO:0033183) histone H2A K63-linked ubiquitination(GO:0070535) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.6 GO:0006020 inositol metabolic process(GO:0006020)
0.0 1.3 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 2.7 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 1.7 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.0 0.5 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 1.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.8 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 2.7 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 1.3 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 1.9 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 1.1 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 2.3 GO:0032886 regulation of microtubule-based process(GO:0032886)
0.0 0.3 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.4 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 0.8 GO:0006400 tRNA modification(GO:0006400)
0.0 0.1 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.5 GO:0090398 cellular senescence(GO:0090398)
0.0 0.1 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.1 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.0 0.0 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) maintenance of mitochondrion location(GO:0051659) relaxation of skeletal muscle(GO:0090076)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 3.9 GO:0030335 positive regulation of cell migration(GO:0030335)
0.0 0.3 GO:0016311 dephosphorylation(GO:0016311)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.6 GO:0071746 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
2.8 33.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
1.8 5.3 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
1.7 15.1 GO:0072546 ER membrane protein complex(GO:0072546)
1.6 9.4 GO:0030905 retromer, tubulation complex(GO:0030905)
1.3 6.4 GO:1990393 3M complex(GO:1990393)
1.2 9.5 GO:0042824 MHC class I peptide loading complex(GO:0042824)
1.1 10.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
1.1 12.7 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
1.0 12.5 GO:0005642 annulate lamellae(GO:0005642)
1.0 6.2 GO:0008537 proteasome activator complex(GO:0008537)
1.0 2.9 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.9 4.4 GO:1990425 ryanodine receptor complex(GO:1990425)
0.9 4.3 GO:0097513 myosin II filament(GO:0097513)
0.8 11.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.8 3.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.7 6.8 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.7 5.4 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.6 4.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.6 7.9 GO:0016600 flotillin complex(GO:0016600)
0.5 9.7 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.5 4.4 GO:0005638 lamin filament(GO:0005638)
0.5 2.4 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.5 3.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.5 3.6 GO:0000322 storage vacuole(GO:0000322)
0.4 4.9 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.4 1.3 GO:0002139 stereocilia coupling link(GO:0002139)
0.4 10.5 GO:0016580 Sin3 complex(GO:0016580)
0.4 3.9 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.4 8.2 GO:0001891 phagocytic cup(GO:0001891)
0.4 5.7 GO:0031209 SCAR complex(GO:0031209)
0.4 3.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.4 16.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.4 9.0 GO:0071004 U2-type prespliceosome(GO:0071004)
0.4 1.1 GO:0030314 junctional membrane complex(GO:0030314)
0.3 15.7 GO:0045095 keratin filament(GO:0045095)
0.3 5.2 GO:0030122 AP-2 adaptor complex(GO:0030122) endolysosome membrane(GO:0036020)
0.3 2.7 GO:0001739 sex chromatin(GO:0001739)
0.3 3.1 GO:0030008 TRAPP complex(GO:0030008)
0.2 7.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 4.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.2 7.6 GO:0000421 autophagosome membrane(GO:0000421)
0.2 29.3 GO:0043202 lysosomal lumen(GO:0043202)
0.2 4.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 2.1 GO:0090543 Flemming body(GO:0090543)
0.2 1.9 GO:0005614 interstitial matrix(GO:0005614)
0.2 3.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 7.5 GO:0001533 cornified envelope(GO:0001533)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.3 GO:0042788 polysomal ribosome(GO:0042788)
0.1 2.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 24.6 GO:0031968 mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968)
0.1 22.8 GO:0072562 blood microparticle(GO:0072562)
0.1 1.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 3.3 GO:0090544 BAF-type complex(GO:0090544)
0.1 0.9 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 1.6 GO:0031264 death-inducing signaling complex(GO:0031264)
0.1 4.4 GO:0045171 intercellular bridge(GO:0045171)
0.1 2.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 4.2 GO:0014704 intercalated disc(GO:0014704)
0.1 3.2 GO:0097542 ciliary tip(GO:0097542)
0.1 5.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 6.3 GO:0005643 nuclear pore(GO:0005643)
0.1 0.8 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 3.9 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 7.2 GO:0005903 brush border(GO:0005903)
0.1 3.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 2.8 GO:0031519 PcG protein complex(GO:0031519)
0.1 0.9 GO:0031528 microvillus membrane(GO:0031528)
0.0 2.4 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.8 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.8 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.5 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 1.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 2.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 2.0 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.4 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 3.5 GO:0016605 PML body(GO:0016605)
0.0 1.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 10.9 GO:0005925 focal adhesion(GO:0005925)
0.0 1.2 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.0 2.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 3.0 GO:0001650 fibrillar center(GO:0001650)
0.0 1.4 GO:0005811 lipid particle(GO:0005811)
0.0 1.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.4 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 16.4 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 6.3 GO:0000785 chromatin(GO:0000785)
0.0 1.8 GO:0005681 spliceosomal complex(GO:0005681)
0.0 1.9 GO:0005769 early endosome(GO:0005769)
0.0 0.1 GO:0008091 spectrin(GO:0008091)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 13.7 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
2.1 16.5 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
1.9 9.4 GO:1990460 leptin receptor binding(GO:1990460)
1.4 4.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
1.3 12.7 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
1.2 3.7 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
1.2 4.9 GO:0004566 beta-glucuronidase activity(GO:0004566)
1.2 9.5 GO:0001849 complement component C1q binding(GO:0001849)
1.1 9.0 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
1.1 4.3 GO:0016748 succinyltransferase activity(GO:0016748)
1.1 5.3 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.9 3.6 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.9 3.6 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.9 6.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.9 2.6 GO:0016730 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.8 5.7 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.8 23.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.7 20.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.7 7.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.7 2.9 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.7 2.1 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.7 6.8 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.6 2.5 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.6 4.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.6 8.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.6 9.0 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.6 1.8 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.6 1.7 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.6 3.9 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.6 1.7 GO:0032427 GBD domain binding(GO:0032427)
0.5 2.2 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.5 7.5 GO:0031996 thioesterase binding(GO:0031996)
0.5 2.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.5 7.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.5 2.0 GO:0004348 glucosylceramidase activity(GO:0004348)
0.4 6.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.4 5.8 GO:0004985 opioid receptor activity(GO:0004985)
0.4 11.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.4 4.3 GO:0030274 LIM domain binding(GO:0030274)
0.4 4.4 GO:0042301 phosphate ion binding(GO:0042301)
0.3 6.1 GO:0048185 activin binding(GO:0048185)
0.3 15.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.3 3.6 GO:0051525 NFAT protein binding(GO:0051525)
0.3 2.0 GO:0003998 acylphosphatase activity(GO:0003998)
0.3 6.5 GO:0051400 BH domain binding(GO:0051400)
0.3 22.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.3 10.6 GO:0019956 chemokine binding(GO:0019956)
0.3 9.0 GO:0070064 proline-rich region binding(GO:0070064)
0.3 3.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.3 4.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.3 1.9 GO:0045545 syndecan binding(GO:0045545)
0.3 2.1 GO:0050692 DBD domain binding(GO:0050692)
0.2 5.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 5.2 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 3.6 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.2 2.7 GO:0045159 myosin II binding(GO:0045159)
0.2 23.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.2 4.0 GO:0097602 cullin family protein binding(GO:0097602)
0.2 0.6 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.2 4.6 GO:0001056 RNA polymerase III activity(GO:0001056)
0.2 3.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.2 2.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 4.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 43.5 GO:0003823 antigen binding(GO:0003823)
0.2 3.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 2.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2 8.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.2 0.7 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.2 0.8 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2 3.9 GO:0070402 NADPH binding(GO:0070402)
0.2 3.9 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 11.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 8.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 0.8 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.1 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1 1.6 GO:0016004 phospholipase activator activity(GO:0016004)
0.1 4.8 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 0.7 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.1 2.4 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.1 3.0 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.6 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 3.2 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.6 GO:1990254 keratin filament binding(GO:1990254)
0.1 2.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 2.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 4.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 2.1 GO:0001848 complement binding(GO:0001848)
0.1 1.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 3.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 1.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 2.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 3.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 1.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 1.3 GO:0046961 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 1.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 15.1 GO:0030246 carbohydrate binding(GO:0030246)
0.1 1.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.5 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 2.4 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.8 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.4 GO:0016773 phosphotransferase activity, alcohol group as acceptor(GO:0016773)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 2.2 GO:0005518 collagen binding(GO:0005518)
0.0 1.4 GO:0050699 WW domain binding(GO:0050699)
0.0 1.5 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 3.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 5.4 GO:0042393 histone binding(GO:0042393)
0.0 5.2 GO:0008201 heparin binding(GO:0008201)
0.0 1.8 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 3.6 GO:0003682 chromatin binding(GO:0003682)
0.0 1.6 GO:0004386 helicase activity(GO:0004386)
0.0 0.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 4.5 GO:0031625 ubiquitin protein ligase binding(GO:0031625)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 21.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.3 10.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.3 3.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.2 15.4 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.2 4.4 PID ALK2 PATHWAY ALK2 signaling events
0.2 10.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.2 6.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.2 14.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 3.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 6.7 PID EPO PATHWAY EPO signaling pathway
0.1 5.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 2.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 9.0 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 8.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 3.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 0.9 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 11.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 3.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 4.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 5.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 1.5 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 3.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 5.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 1.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.4 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.5 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.6 PID INSULIN PATHWAY Insulin Pathway
0.0 1.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.6 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 1.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.5 PID ATM PATHWAY ATM pathway
0.0 0.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.9 PID P73PATHWAY p73 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 23.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.7 9.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.4 23.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.3 4.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.3 14.4 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.3 12.0 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.3 8.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.3 5.7 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.3 6.8 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.3 41.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.3 3.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.3 19.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.3 4.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.3 5.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 12.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2 2.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 5.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.2 5.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.2 4.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 4.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 6.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 4.6 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.2 0.7 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.2 14.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.2 3.9 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.2 3.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 3.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 16.2 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.2 2.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 6.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 10.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 21.5 REACTOME TRANSLATION Genes involved in Translation
0.1 3.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.1 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 11.6 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.1 1.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 4.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.1 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 2.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 2.0 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 6.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.9 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 2.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 3.7 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 1.1 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.2 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF