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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for KLF15

Z-value: 0.88

Motif logo

Transcription factors associated with KLF15

Gene Symbol Gene ID Gene Info
ENSG00000163884.3 Kruppel like factor 15

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF15hg19_v2_chr3_-_126076264_1260763050.504.3e-15Click!

Activity profile of KLF15 motif

Sorted Z-values of KLF15 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_77681075 17.83 ENST00000397549.2
CTD-2116F7.1
chr6_+_111580508 12.53 ENST00000368847.4
KIAA1919
chr12_+_53773944 11.63 ENST00000551969.1
ENST00000327443.4
Sp1 transcription factor
chrX_+_16737718 10.95 ENST00000380155.3
synapse associated protein 1
chr22_+_29469100 10.05 ENST00000327813.5
ENST00000407188.1
kringle containing transmembrane protein 1
chr5_+_17217669 9.09 ENST00000322611.3
brain abundant, membrane attached signal protein 1
chrX_+_23352133 8.58 ENST00000379361.4
patched domain containing 1
chr6_+_43543864 8.50 ENST00000372236.4
ENST00000535400.1
polymerase (DNA directed), eta
chr11_-_64410787 8.27 ENST00000301894.2
neurexin 2
chr5_-_11904100 8.08 ENST00000359640.2
catenin (cadherin-associated protein), delta 2
chr15_-_45480153 8.01 ENST00000560471.1
ENST00000560540.1
Src homology 2 domain containing F
chr10_+_74451883 7.71 ENST00000373053.3
ENST00000357157.6
mitochondrial calcium uniporter
chr7_+_65338230 7.50 ENST00000360768.3
vitamin K epoxide reductase complex, subunit 1-like 1
chr2_-_220173685 7.44 ENST00000423636.2
ENST00000442029.1
ENST00000412847.1
protein tyrosine phosphatase, receptor type, N
chr7_-_143059780 7.38 ENST00000409578.1
ENST00000409346.1
family with sequence similarity 131, member B
chr5_-_11904152 7.14 ENST00000304623.8
ENST00000458100.2
catenin (cadherin-associated protein), delta 2
chr19_-_55866104 7.12 ENST00000326529.4
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr19_-_47975417 7.10 ENST00000236877.6
solute carrier family 8 (sodium/calcium exchanger), member 2
chr3_+_101546827 7.04 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr6_+_43543942 7.03 ENST00000372226.1
ENST00000443535.1
polymerase (DNA directed), eta
chr1_+_228353495 7.01 ENST00000366711.3
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr10_+_76871353 7.01 ENST00000542569.1
sterile alpha motif domain containing 8
chr12_-_123215306 6.99 ENST00000356987.2
ENST00000436083.2
hydroxycarboxylic acid receptor 1
chr14_-_21493884 6.80 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
NDRG family member 2
chr18_-_51750948 6.58 ENST00000583046.1
ENST00000398398.2
methyl-CpG binding domain protein 2
chr11_+_17756279 6.09 ENST00000265969.6
potassium voltage-gated channel, Shaw-related subfamily, member 1
chr19_-_49576198 6.06 ENST00000221444.1
potassium voltage-gated channel, shaker-related subfamily, member 7
chr12_-_54982300 6.04 ENST00000547431.1
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr2_-_9143786 5.95 ENST00000462696.1
ENST00000305997.3
membrane bound O-acyltransferase domain containing 2
chr16_+_56225248 5.90 ENST00000262493.6
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr10_+_76871454 5.79 ENST00000372687.4
sterile alpha motif domain containing 8
chr8_+_9413410 5.60 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr12_+_53443680 5.54 ENST00000314250.6
ENST00000451358.1
tensin like C1 domain containing phosphatase (tensin 2)
chr19_-_38806560 5.52 ENST00000591755.1
ENST00000337679.8
ENST00000339413.6
Yip1 interacting factor homolog B (S. cerevisiae)
chr14_-_21493649 5.50 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG family member 2
chr2_-_176866978 5.49 ENST00000392540.2
ENST00000409660.1
ENST00000544803.1
ENST00000272748.4
KIAA1715
chr12_+_9067123 5.35 ENST00000543824.1
polyhomeotic homolog 1 (Drosophila)
chr12_+_53443963 5.31 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
tensin like C1 domain containing phosphatase (tensin 2)
chr3_+_14989076 5.25 ENST00000413118.1
ENST00000425241.1
nuclear receptor subfamily 2, group C, member 2
chr19_+_10531150 5.18 ENST00000352831.6
phosphodiesterase 4A, cAMP-specific
chr1_-_32229934 5.15 ENST00000398542.1
brain-specific angiogenesis inhibitor 2
chr16_+_50187556 5.05 ENST00000561678.1
ENST00000357464.3
PAP associated domain containing 5
chr11_-_62457371 4.85 ENST00000317449.4
LRRN4 C-terminal like
chr12_+_9067327 4.83 ENST00000433083.2
ENST00000544916.1
ENST00000544539.1
ENST00000539063.1
polyhomeotic homolog 1 (Drosophila)
chr18_+_56530136 4.79 ENST00000591083.1
zinc finger protein 532
chr1_-_32229523 4.77 ENST00000398547.1
ENST00000373655.2
ENST00000373658.3
ENST00000257070.4
brain-specific angiogenesis inhibitor 2
chr14_+_32546274 4.75 ENST00000396582.2
Rho GTPase activating protein 5
chr3_+_238273 4.70 ENST00000256509.2
cell adhesion molecule L1-like
chr9_-_111929560 4.66 ENST00000561981.2
ferric-chelate reductase 1-like
chr2_+_5832799 4.66 ENST00000322002.3
SRY (sex determining region Y)-box 11
chr3_-_52001448 4.58 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
poly(rC) binding protein 4
chr21_+_27107672 4.55 ENST00000400075.3
GA binding protein transcription factor, alpha subunit 60kDa
chr17_-_78450398 4.53 ENST00000306773.4
neuronal pentraxin I
chr12_-_54982420 4.49 ENST00000257905.8
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr3_-_149688502 4.49 ENST00000481767.1
ENST00000475518.1
profilin 2
chrX_-_153881842 4.45 ENST00000369585.3
ENST00000247306.4
cancer/testis antigen 2
chr7_-_105029329 4.42 ENST00000393651.3
ENST00000460391.1
SRSF protein kinase 2
chr4_+_55524085 4.40 ENST00000412167.2
ENST00000288135.5
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr19_-_46272462 4.38 ENST00000317578.6
SIX homeobox 5
chr14_-_21493123 4.37 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
NDRG family member 2
chr19_-_55866061 4.36 ENST00000588572.2
ENST00000593184.1
ENST00000589467.1
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr15_+_64752927 4.31 ENST00000416172.1
zinc finger protein 609
chr2_-_37193606 4.25 ENST00000379213.2
ENST00000263918.4
striatin, calmodulin binding protein
chr17_-_41984835 4.25 ENST00000520406.1
ENST00000518478.1
ENST00000522172.1
ENST00000461854.1
ENST00000521178.1
ENST00000520305.1
ENST00000523501.1
ENST00000520241.1
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr12_-_6798616 4.24 ENST00000355772.4
ENST00000417772.3
ENST00000396801.3
ENST00000396799.2
zinc finger protein 384
chr12_-_123849374 4.22 ENST00000602398.1
ENST00000602750.1
strawberry notch homolog 1 (Drosophila)
chr3_+_111718173 4.17 ENST00000494932.1
transgelin 3
chr7_+_29519662 4.07 ENST00000424025.2
ENST00000439711.2
ENST00000421775.2
chimerin 2
chr22_+_19118321 4.03 ENST00000399635.2
testis-specific serine kinase 2
chr5_-_73937244 3.99 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ectodermal-neural cortex 1 (with BTB domain)
chr12_-_6798410 3.92 ENST00000361959.3
ENST00000436774.2
ENST00000544482.1
zinc finger protein 384
chr11_-_72353451 3.88 ENST00000376450.3
phosphodiesterase 2A, cGMP-stimulated
chr1_+_97187318 3.86 ENST00000609116.1
ENST00000370198.1
ENST00000370197.1
ENST00000426398.2
ENST00000394184.3
polypyrimidine tract binding protein 2
chr17_-_15168624 3.82 ENST00000312280.3
ENST00000494511.1
ENST00000580584.1
peripheral myelin protein 22
chrX_+_70316005 3.81 ENST00000374259.3
forkhead box O4
chr12_-_6798523 3.79 ENST00000319770.3
zinc finger protein 384
chr5_+_140254884 3.78 ENST00000398631.2
protocadherin alpha 12
chr12_-_112819896 3.77 ENST00000377560.5
ENST00000430131.2
ENST00000550722.1
ENST00000550724.1
HECT domain containing E3 ubiquitin protein ligase 4
chr3_+_46923670 3.71 ENST00000427125.2
ENST00000430002.2
parathyroid hormone 1 receptor
chr10_+_60272814 3.71 ENST00000373886.3
bicaudal C homolog 1 (Drosophila)
chr17_-_41985096 3.67 ENST00000269095.4
ENST00000523220.1
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr11_-_31839488 3.65 ENST00000419022.1
ENST00000379132.3
ENST00000379129.2
paired box 6
chr11_-_8954491 3.65 ENST00000526227.1
ENST00000525780.1
ENST00000326053.5
chromosome 11 open reading frame 16
chr3_+_9851632 3.53 ENST00000426895.4
tubulin tyrosine ligase-like family, member 3
chr7_-_92157760 3.52 ENST00000248633.4
peroxisomal biogenesis factor 1
chr1_-_177133818 3.50 ENST00000424564.2
ENST00000361833.2
astrotactin 1
chr19_+_50706866 3.48 ENST00000440075.2
ENST00000376970.2
ENST00000425460.1
ENST00000599920.1
ENST00000601313.1
myosin, heavy chain 14, non-muscle
chr1_-_241520525 3.47 ENST00000366565.1
regulator of G-protein signaling 7
chr6_+_31865552 3.43 ENST00000469372.1
ENST00000497706.1
complement component 2
chr18_-_21977748 3.42 ENST00000399441.4
ENST00000319481.3
oxysterol binding protein-like 1A
chr14_+_24837226 3.33 ENST00000554050.1
ENST00000554903.1
ENST00000554779.1
ENST00000250373.4
ENST00000553708.1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
chr1_-_47407111 3.29 ENST00000371904.4
cytochrome P450, family 4, subfamily A, polypeptide 11
chr12_-_48213568 3.27 ENST00000080059.7
ENST00000354334.3
ENST00000430670.1
ENST00000552960.1
ENST00000440293.1
histone deacetylase 7
chr18_-_57364588 3.27 ENST00000439986.4
collagen and calcium binding EGF domains 1
chr15_-_34629922 3.23 ENST00000559484.1
ENST00000354181.3
ENST00000558589.1
ENST00000458406.2
solute carrier family 12 (potassium/chloride transporter), member 6
chr17_-_4464081 3.23 ENST00000574154.1
gamma-glutamyltransferase 6
chr15_-_34630234 3.19 ENST00000558667.1
ENST00000561120.1
ENST00000559236.1
ENST00000397702.2
solute carrier family 12 (potassium/chloride transporter), member 6
chr9_-_14313641 3.16 ENST00000380953.1
nuclear factor I/B
chrX_+_51927919 3.13 ENST00000416960.1
melanoma antigen family D, 4
chr17_-_4463856 3.12 ENST00000574584.1
ENST00000381550.3
ENST00000301395.3
gamma-glutamyltransferase 6
chr7_+_94285637 3.11 ENST00000482108.1
ENST00000488574.1
paternally expressed 10
chrX_-_65858865 3.11 ENST00000374719.3
ENST00000450752.1
ENST00000451436.2
ectodysplasin A2 receptor
chr1_-_205313304 3.07 ENST00000539253.1
ENST00000607826.1
kelch domain containing 8A
chr7_-_767249 3.07 ENST00000403562.1
protein kinase, cAMP-dependent, regulatory, type I, beta
chr11_+_119076745 3.07 ENST00000264033.4
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr3_-_156272924 3.05 ENST00000467789.1
ENST00000265044.2
signal sequence receptor, gamma (translocon-associated protein gamma)
chr10_+_35416223 3.03 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
cAMP responsive element modulator
chr2_-_242254595 3.03 ENST00000441124.1
ENST00000391976.2
high density lipoprotein binding protein
chr20_-_45280091 3.03 ENST00000396360.1
ENST00000435032.1
ENST00000413164.2
ENST00000372121.1
ENST00000339636.3
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
chr20_-_45280066 3.02 ENST00000279027.4
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
chr1_-_151689259 2.95 ENST00000420342.1
ENST00000290583.4
CUGBP, Elav-like family member 3
chr17_+_36508111 2.94 ENST00000331159.5
ENST00000577233.1
suppressor of cytokine signaling 7
chrX_-_48693955 2.88 ENST00000218230.5
proprotein convertase subtilisin/kexin type 1 inhibitor
chr14_+_32546485 2.87 ENST00000345122.3
ENST00000432921.1
ENST00000433497.1
Rho GTPase activating protein 5
chr20_+_62711482 2.83 ENST00000336866.2
ENST00000355631.4
opiate receptor-like 1
chrX_-_65859096 2.83 ENST00000456230.2
ectodysplasin A2 receptor
chrY_+_4868267 2.79 ENST00000333703.4
protocadherin 11 Y-linked
chr2_-_220174166 2.78 ENST00000409251.3
ENST00000451506.1
ENST00000295718.2
ENST00000446182.1
protein tyrosine phosphatase, receptor type, N
chr7_-_92157747 2.77 ENST00000428214.1
ENST00000438045.1
peroxisomal biogenesis factor 1
chr19_-_40791211 2.75 ENST00000579047.1
v-akt murine thymoma viral oncogene homolog 2
chr11_-_65640325 2.74 ENST00000307998.6
EGF containing fibulin-like extracellular matrix protein 2
chr19_-_14117074 2.73 ENST00000588885.1
ENST00000254325.4
regulatory factor X, 1 (influences HLA class II expression)
chr11_-_73309228 2.73 ENST00000356467.4
ENST00000064778.4
family with sequence similarity 168, member A
chr14_+_33408449 2.73 ENST00000346562.2
ENST00000341321.4
ENST00000548645.1
ENST00000356141.4
ENST00000357798.5
neuronal PAS domain protein 3
chr1_-_241520385 2.70 ENST00000366564.1
regulator of G-protein signaling 7
chr6_+_41606176 2.64 ENST00000441667.1
ENST00000230321.6
ENST00000373050.4
ENST00000446650.1
ENST00000435476.1
MyoD family inhibitor
chr1_-_243418621 2.64 ENST00000366544.1
ENST00000366543.1
centrosomal protein 170kDa
chr10_-_79397391 2.63 ENST00000286628.8
ENST00000406533.3
ENST00000354353.5
ENST00000404857.1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr6_-_29595779 2.63 ENST00000355973.3
ENST00000377012.4
gamma-aminobutyric acid (GABA) B receptor, 1
chr7_+_29519486 2.63 ENST00000409041.4
chimerin 2
chr4_-_5890145 2.62 ENST00000397890.2
collapsin response mediator protein 1
chr2_+_135676381 2.60 ENST00000537343.1
ENST00000295238.6
ENST00000264157.5
cyclin T2
chr2_+_48757278 2.59 ENST00000404752.1
ENST00000406226.1
stonin 1
chr10_+_74927875 2.56 ENST00000242505.6
family with sequence similarity 149, member B1
chr22_+_29469012 2.56 ENST00000400335.4
ENST00000400338.2
kringle containing transmembrane protein 1
chr3_+_12838161 2.55 ENST00000456430.2
cullin-associated and neddylation-dissociated 2 (putative)
chr2_-_25564750 2.55 ENST00000321117.5
DNA (cytosine-5-)-methyltransferase 3 alpha
chr14_+_59655369 2.53 ENST00000360909.3
ENST00000351081.1
ENST00000556135.1
dishevelled associated activator of morphogenesis 1
chr15_-_86338134 2.52 ENST00000337975.5
kelch-like family member 25
chr3_-_105587879 2.50 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr21_-_45681765 2.47 ENST00000431166.1
DNA (cytosine-5-)-methyltransferase 3-like
chr8_+_30241995 2.46 ENST00000397323.4
ENST00000339877.4
ENST00000320203.4
ENST00000287771.5
RNA binding protein with multiple splicing
chr1_-_204654481 2.45 ENST00000367176.3
leucine rich repeat neuronal 2
chr2_-_31361543 2.45 ENST00000349752.5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr1_-_32801825 2.45 ENST00000329421.7
MARCKS-like 1
chr22_+_31090793 2.43 ENST00000332585.6
ENST00000382310.3
ENST00000446658.2
oxysterol binding protein 2
chr4_-_170947485 2.42 ENST00000504999.1
microfibrillar-associated protein 3-like
chr19_-_51456198 2.41 ENST00000594846.1
kallikrein-related peptidase 5
chr3_+_38495333 2.40 ENST00000352511.4
activin A receptor, type IIB
chr3_+_184279566 2.35 ENST00000330394.2
EPH receptor B3
chr8_+_55370487 2.34 ENST00000297316.4
SRY (sex determining region Y)-box 17
chr15_-_88799948 2.31 ENST00000394480.2
neurotrophic tyrosine kinase, receptor, type 3
chr9_+_140772226 2.31 ENST00000277551.2
ENST00000371372.1
ENST00000277549.5
ENST00000371363.1
ENST00000371357.1
ENST00000371355.4
calcium channel, voltage-dependent, N type, alpha 1B subunit
chr17_-_4545170 2.30 ENST00000576394.1
ENST00000574640.1
arachidonate 15-lipoxygenase
chr1_-_244013384 2.30 ENST00000366539.1
v-akt murine thymoma viral oncogene homolog 3
chr20_-_48099182 2.30 ENST00000371741.4
potassium voltage-gated channel, Shab-related subfamily, member 1
chr3_+_11034403 2.29 ENST00000287766.4
ENST00000425938.1
solute carrier family 6 (neurotransmitter transporter), member 1
chrX_-_17878827 2.29 ENST00000360011.1
retinoic acid induced 2
chr7_-_108096822 2.27 ENST00000379028.3
ENST00000413765.2
ENST00000379022.4
neuronal cell adhesion molecule
chr19_+_15218180 2.27 ENST00000342784.2
ENST00000597977.1
ENST00000600440.1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr15_-_86338100 2.26 ENST00000536947.1
kelch-like family member 25
chr13_-_108867846 2.26 ENST00000442234.1
ligase IV, DNA, ATP-dependent
chr7_-_108096765 2.25 ENST00000379024.4
ENST00000351718.4
neuronal cell adhesion molecule
chr9_+_101867387 2.25 ENST00000374990.2
ENST00000552516.1
transforming growth factor, beta receptor 1
chr3_-_188665428 2.22 ENST00000444488.1
TPRG1 antisense RNA 1
chr12_+_57853918 2.22 ENST00000532291.1
ENST00000543426.1
ENST00000228682.2
ENST00000546141.1
GLI family zinc finger 1
chr1_-_113498943 2.20 ENST00000369626.3
solute carrier family 16 (monocarboxylate transporter), member 1
chr11_-_117103208 2.17 ENST00000320934.3
ENST00000530269.1
proprotein convertase subtilisin/kexin type 7
chr11_-_6677018 2.16 ENST00000299441.3
dachsous cadherin-related 1
chr9_-_84303269 2.16 ENST00000418319.1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr5_-_141257954 2.13 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
protocadherin 1
chr6_-_131384412 2.12 ENST00000445890.2
ENST00000368128.2
ENST00000337057.3
erythrocyte membrane protein band 4.1-like 2
chr4_+_74702214 2.10 ENST00000226317.5
ENST00000515050.1
chemokine (C-X-C motif) ligand 6
chr7_+_144052381 2.08 ENST00000498580.1
ENST00000056217.5
Rho guanine nucleotide exchange factor (GEF) 5
chr10_+_35415978 2.08 ENST00000429130.3
ENST00000469949.2
ENST00000460270.1
cAMP responsive element modulator
chr6_+_149068464 2.07 ENST00000367463.4
uronyl-2-sulfotransferase
chr16_-_62070305 2.07 ENST00000584337.1
cadherin 8, type 2
chrX_+_11776278 2.06 ENST00000312196.4
ENST00000337339.2
male-specific lethal 3 homolog (Drosophila)
chr1_+_154975110 2.06 ENST00000535420.1
ENST00000368426.3
zinc finger and BTB domain containing 7B
chr14_+_24867992 2.05 ENST00000382554.3
NYN domain and retroviral integrase containing
chr2_+_24272543 2.04 ENST00000380991.4
FK506 binding protein 1B, 12.6 kDa
chr3_-_10547333 2.03 ENST00000383800.4
ATPase, Ca++ transporting, plasma membrane 2
chr3_-_49726486 2.01 ENST00000449682.2
macrophage stimulating 1 (hepatocyte growth factor-like)
chr1_+_41249539 2.01 ENST00000347132.5
ENST00000509682.2
potassium voltage-gated channel, KQT-like subfamily, member 4
chr10_-_133795416 2.00 ENST00000540159.1
ENST00000368636.4
BCL2/adenovirus E1B 19kDa interacting protein 3
chr20_+_20348740 1.99 ENST00000310227.1
insulinoma-associated 1
chr14_-_104313824 1.99 ENST00000553739.1
ENST00000202556.9
protein phosphatase 1, regulatory subunit 13B
chr19_+_45754505 1.98 ENST00000262891.4
ENST00000300843.4
MAP/microtubule affinity-regulating kinase 4
chr19_+_589893 1.98 ENST00000251287.2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr22_+_39745930 1.96 ENST00000318801.4
ENST00000216155.7
ENST00000406293.3
ENST00000328933.5
synaptogyrin 1
chr1_-_179198702 1.95 ENST00000502732.1
c-abl oncogene 2, non-receptor tyrosine kinase
chr4_-_39640700 1.93 ENST00000295958.5
small integral membrane protein 14
chr21_-_40685504 1.93 ENST00000380800.3
bromodomain and WD repeat domain containing 1
chr6_+_44238203 1.92 ENST00000451188.2
transmembrane protein 151B
chr18_+_13218769 1.91 ENST00000399848.3
ENST00000361205.4
low density lipoprotein receptor class A domain containing 4
chr7_+_66205643 1.90 ENST00000380828.2
ENST00000510829.2
potassium channel tetramerization domain containing 7
chr7_-_94285402 1.89 ENST00000428696.2
ENST00000445866.2
sarcoglycan, epsilon
chr1_-_227506158 1.88 ENST00000366769.3
CDC42 binding protein kinase alpha (DMPK-like)
chrX_+_119495934 1.86 ENST00000218008.3
ENST00000361319.3
ENST00000539306.1
ATPase, Na+/K+ transporting, beta 4 polypeptide
chr3_-_12200851 1.86 ENST00000287814.4
TIMP metallopeptidase inhibitor 4

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF15

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.2 GO:1990502 dense core granule maturation(GO:1990502)
2.2 15.5 GO:0071494 cellular response to UV-C(GO:0071494)
2.1 6.3 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
2.1 6.2 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
2.0 11.9 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
1.9 5.6 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
1.8 9.1 GO:2001076 regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
1.6 12.9 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
1.6 4.7 GO:0061386 closure of optic fissure(GO:0061386)
1.5 1.5 GO:0007356 thorax and anterior abdomen determination(GO:0007356)
1.5 6.1 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
1.4 6.8 GO:0021759 globus pallidus development(GO:0021759)
1.4 5.4 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
1.3 3.9 GO:0052026 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
1.3 3.9 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
1.3 7.7 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
1.3 6.4 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
1.2 4.8 GO:0018094 protein polyglycylation(GO:0018094)
1.2 3.5 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
1.0 16.7 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
1.0 8.3 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
1.0 3.8 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317) response to water-immersion restraint stress(GO:1990785)
1.0 4.8 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.9 4.4 GO:0035063 nuclear speck organization(GO:0035063)
0.9 2.6 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.9 6.0 GO:2000795 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.8 7.5 GO:0042373 vitamin K metabolic process(GO:0042373)
0.8 3.3 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.8 3.3 GO:1905075 proepicardium development(GO:0003342) septum transversum development(GO:0003343) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.8 4.0 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.8 2.3 GO:0009996 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of cell fate specification(GO:0009996) gall bladder development(GO:0061010)
0.8 3.1 GO:0003095 pressure natriuresis(GO:0003095)
0.8 9.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.8 2.3 GO:2001303 cellular response to interleukin-13(GO:0035963) lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.8 4.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.8 2.3 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.7 2.2 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.7 3.7 GO:0003322 pancreatic A cell development(GO:0003322)
0.7 5.1 GO:0043634 polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.7 2.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.7 4.3 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.7 2.8 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.7 2.0 GO:0003358 noradrenergic neuron development(GO:0003358)
0.7 3.3 GO:1901490 regulation of lymphangiogenesis(GO:1901490)
0.6 4.5 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.6 2.6 GO:0019086 late viral transcription(GO:0019086)
0.6 2.5 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.6 7.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.6 2.3 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.6 2.3 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.6 8.6 GO:0021794 thalamus development(GO:0021794)
0.6 9.1 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.6 2.2 GO:0021938 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.5 2.2 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.5 2.1 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.5 2.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.5 3.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.5 2.0 GO:0071321 cellular response to cGMP(GO:0071321)
0.5 1.9 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.5 3.7 GO:0098870 neuronal action potential propagation(GO:0019227) positive regulation of axon regeneration(GO:0048680) action potential propagation(GO:0098870)
0.5 5.9 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.5 6.3 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.5 4.5 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.4 4.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.4 1.7 GO:0097368 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.4 3.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.4 2.0 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637) cellular response to cobalt ion(GO:0071279)
0.4 4.0 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.4 4.1 GO:0034465 response to carbon monoxide(GO:0034465) negative regulation of cell volume(GO:0045794)
0.4 0.7 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.4 4.5 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.4 1.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.4 2.9 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.4 1.8 GO:0072240 thick ascending limb development(GO:0072023) DCT cell differentiation(GO:0072069) metanephric thick ascending limb development(GO:0072233) metanephric DCT cell differentiation(GO:0072240)
0.3 2.1 GO:0006477 protein sulfation(GO:0006477)
0.3 0.7 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.3 7.0 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.3 0.9 GO:0048865 stem cell fate commitment(GO:0048865)
0.3 1.5 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.3 1.5 GO:0086053 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.3 0.9 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.3 1.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.3 4.3 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.3 3.5 GO:0071625 vocalization behavior(GO:0071625)
0.3 3.4 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.3 2.6 GO:0010265 SCF complex assembly(GO:0010265)
0.2 4.5 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.2 1.0 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.2 2.4 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.2 2.1 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.2 3.0 GO:0030575 nuclear body organization(GO:0030575)
0.2 2.9 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.2 5.1 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479)
0.2 7.9 GO:0046710 GDP metabolic process(GO:0046710)
0.2 0.4 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.2 0.4 GO:2000542 negative regulation of gastrulation(GO:2000542)
0.2 2.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 1.7 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.2 1.7 GO:0060074 synapse maturation(GO:0060074)
0.2 6.4 GO:0035640 exploration behavior(GO:0035640)
0.2 6.0 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.2 13.7 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.2 3.8 GO:0032060 bleb assembly(GO:0032060)
0.2 1.6 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 1.8 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.2 1.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.2 2.1 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.2 1.9 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.2 5.2 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.2 2.1 GO:0015074 DNA integration(GO:0015074)
0.2 1.1 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.2 1.4 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 3.5 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 3.7 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1 1.3 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
0.1 2.6 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 0.4 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 12.6 GO:0030279 negative regulation of ossification(GO:0030279)
0.1 1.3 GO:0002870 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.1 1.2 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.1 2.3 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 5.9 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.1 2.4 GO:0098761 interleukin-7-mediated signaling pathway(GO:0038111) response to interleukin-7(GO:0098760) cellular response to interleukin-7(GO:0098761)
0.1 1.1 GO:0016584 nucleosome positioning(GO:0016584)
0.1 2.9 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.1 2.2 GO:2000811 negative regulation of anoikis(GO:2000811)
0.1 2.4 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.1 1.9 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1 3.0 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 3.0 GO:0048265 response to pain(GO:0048265)
0.1 0.6 GO:0072017 distal tubule development(GO:0072017)
0.1 1.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 5.1 GO:0016486 peptide hormone processing(GO:0016486)
0.1 3.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.7 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.1 1.4 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 1.6 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 6.4 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 0.5 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.1 0.9 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 2.3 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.1 0.8 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1 2.5 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.1 1.7 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 2.6 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 1.0 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 1.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 3.4 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 1.1 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 2.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.2 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 10.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 4.3 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.1 0.9 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.7 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 4.6 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1 2.7 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.1 2.0 GO:0010863 positive regulation of phospholipase C activity(GO:0010863)
0.0 3.7 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 2.4 GO:0016266 O-glycan processing(GO:0016266)
0.0 1.7 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.7 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 1.2 GO:0090398 cellular senescence(GO:0090398)
0.0 2.0 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 5.7 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 1.7 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 2.9 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.8 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.6 GO:0051931 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 1.4 GO:0001558 regulation of cell growth(GO:0001558)
0.0 8.9 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.5 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.8 GO:0007030 Golgi organization(GO:0007030)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 1.9 GO:0042698 ovulation cycle(GO:0042698)
0.0 0.2 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 2.0 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 1.0 GO:0007032 endosome organization(GO:0007032)
0.0 0.5 GO:0048048 embryonic eye morphogenesis(GO:0048048)
0.0 1.6 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 1.7 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 0.5 GO:0006023 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.0 1.0 GO:0055072 iron ion homeostasis(GO:0055072)
0.0 2.0 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.9 GO:0030282 bone mineralization(GO:0030282)
0.0 0.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.6 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.3 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.4 GO:1901216 positive regulation of neuron death(GO:1901216)
0.0 1.8 GO:0030100 regulation of endocytosis(GO:0030100)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.7 GO:1990246 uniplex complex(GO:1990246)
1.6 11.5 GO:0030061 mitochondrial crista(GO:0030061)
0.9 2.6 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.7 3.5 GO:0097513 myosin II filament(GO:0097513)
0.6 4.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.5 4.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.5 20.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.5 7.6 GO:0035102 PRC1 complex(GO:0035102)
0.5 6.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.4 2.9 GO:0032584 growth cone membrane(GO:0032584)
0.4 5.5 GO:0043083 synaptic cleft(GO:0043083)
0.4 2.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.4 3.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.4 1.1 GO:0031213 RSF complex(GO:0031213)
0.4 7.9 GO:0032591 dendritic spine membrane(GO:0032591)
0.4 5.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.3 6.1 GO:0032590 dendrite membrane(GO:0032590)
0.3 2.1 GO:0072487 MSL complex(GO:0072487)
0.3 4.5 GO:0043194 axon initial segment(GO:0043194)
0.3 39.9 GO:0043204 perikaryon(GO:0043204)
0.3 1.0 GO:0070695 FHF complex(GO:0070695)
0.2 1.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.2 4.4 GO:0005813 centrosome(GO:0005813)
0.2 1.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 2.3 GO:0071953 elastic fiber(GO:0071953)
0.2 7.5 GO:0042629 mast cell granule(GO:0042629)
0.2 1.2 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 1.6 GO:0044294 dendritic growth cone(GO:0044294)
0.2 2.1 GO:0008091 spectrin(GO:0008091)
0.2 0.7 GO:0097470 ribbon synapse(GO:0097470)
0.2 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 3.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 11.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 28.2 GO:0030426 growth cone(GO:0030426)
0.2 3.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 2.4 GO:0097440 apical dendrite(GO:0097440)
0.1 7.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.4 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 3.8 GO:0043218 compact myelin(GO:0043218)
0.1 14.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 2.2 GO:0005922 connexon complex(GO:0005922)
0.1 2.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 11.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 4.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 1.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.9 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 1.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 2.2 GO:0097546 ciliary base(GO:0097546)
0.1 6.1 GO:0034704 calcium channel complex(GO:0034704)
0.1 1.4 GO:0015630 microtubule cytoskeleton(GO:0015630)
0.1 8.2 GO:0005814 centriole(GO:0005814)
0.1 2.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.7 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 8.0 GO:0032587 ruffle membrane(GO:0032587)
0.1 3.7 GO:0031526 brush border membrane(GO:0031526)
0.1 3.3 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 21.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 3.6 GO:0000792 heterochromatin(GO:0000792)
0.1 3.9 GO:0042734 presynaptic membrane(GO:0042734)
0.1 2.3 GO:0031201 SNARE complex(GO:0031201)
0.0 0.7 GO:0000346 transcription export complex(GO:0000346)
0.0 3.8 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 10.2 GO:0098793 presynapse(GO:0098793)
0.0 1.1 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.5 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 3.4 GO:0005770 late endosome(GO:0005770)
0.0 3.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 3.7 GO:0030133 transport vesicle(GO:0030133)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 2.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 2.8 GO:0043197 dendritic spine(GO:0043197)
0.0 1.5 GO:0035580 specific granule lumen(GO:0035580)
0.0 3.0 GO:0001650 fibrillar center(GO:0001650)
0.0 2.3 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.7 GO:0005685 U1 snRNP(GO:0005685)
0.0 4.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.4 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 3.2 GO:0043209 myelin sheath(GO:0043209)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.4 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 1.5 GO:1902554 serine/threonine protein kinase complex(GO:1902554)
0.0 1.6 GO:0005643 nuclear pore(GO:0005643)
0.0 1.5 GO:0031985 Golgi cisterna(GO:0031985)
0.0 57.4 GO:0016021 integral component of membrane(GO:0016021)
0.0 1.2 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.9 GO:0031514 motile cilium(GO:0031514)
0.0 0.5 GO:0016324 apical plasma membrane(GO:0016324)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 12.9 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
1.9 7.5 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
1.5 6.1 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
1.3 10.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
1.2 4.8 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.9 2.6 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.9 3.5 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.8 3.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.8 2.3 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.7 6.0 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.7 3.7 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.7 3.7 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.7 7.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.7 20.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.7 5.6 GO:0097322 7SK snRNA binding(GO:0097322)
0.7 5.5 GO:0034711 inhibin binding(GO:0034711)
0.7 6.6 GO:0003696 satellite DNA binding(GO:0003696)
0.6 3.9 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.6 3.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.6 4.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.6 6.4 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.6 6.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.5 3.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.5 5.9 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.5 8.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.5 2.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.5 2.4 GO:0017002 activin-activated receptor activity(GO:0017002)
0.5 6.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.4 2.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.4 1.7 GO:0035276 ethanol binding(GO:0035276)
0.4 5.3 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.4 6.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.4 9.2 GO:0071837 HMG box domain binding(GO:0071837)
0.4 2.3 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.4 1.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.4 1.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.3 1.7 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.3 4.5 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.3 2.8 GO:0004985 opioid receptor activity(GO:0004985)
0.3 3.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.3 1.5 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.3 0.9 GO:0098770 FBXO family protein binding(GO:0098770)
0.3 0.9 GO:0070984 SET domain binding(GO:0070984)
0.3 1.4 GO:0050436 microfibril binding(GO:0050436)
0.3 0.8 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.3 1.9 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.3 2.9 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.3 4.4 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.2 1.2 GO:0034056 estrogen response element binding(GO:0034056)
0.2 12.3 GO:0030507 spectrin binding(GO:0030507)
0.2 2.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 1.0 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.2 3.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 2.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.2 3.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 7.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 2.3 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.2 2.2 GO:0045545 syndecan binding(GO:0045545)
0.2 8.3 GO:0030552 cAMP binding(GO:0030552)
0.2 3.6 GO:0031005 filamin binding(GO:0031005)
0.2 5.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 3.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 5.9 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2 4.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 0.7 GO:0038025 glycoprotein transporter activity(GO:0034437) reelin receptor activity(GO:0038025)
0.2 2.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 1.6 GO:0008432 JUN kinase binding(GO:0008432)
0.2 4.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 17.4 GO:0008013 beta-catenin binding(GO:0008013)
0.2 3.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 7.6 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 15.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 2.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 8.1 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 1.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 1.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 4.9 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 3.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.7 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 3.4 GO:0015248 sterol transporter activity(GO:0015248)
0.1 3.9 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 1.1 GO:0039706 co-receptor binding(GO:0039706)
0.1 2.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 4.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 1.1 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 1.1 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 1.8 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 3.5 GO:0008009 chemokine activity(GO:0008009)
0.1 3.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 1.7 GO:0001968 fibronectin binding(GO:0001968)
0.1 7.2 GO:0005262 calcium channel activity(GO:0005262)
0.1 1.9 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 1.2 GO:0097602 cullin family protein binding(GO:0097602)
0.1 2.4 GO:0015485 cholesterol binding(GO:0015485)
0.1 2.6 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 0.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.7 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 2.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 5.2 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 2.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 3.3 GO:0005518 collagen binding(GO:0005518)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 4.6 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 2.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 2.1 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 4.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.6 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 8.9 GO:0000287 magnesium ion binding(GO:0000287)
0.0 4.2 GO:0051015 actin filament binding(GO:0051015)
0.0 1.5 GO:0070888 E-box binding(GO:0070888)
0.0 8.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:1990254 keratin filament binding(GO:1990254)
0.0 2.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.9 GO:0015077 monovalent inorganic cation transmembrane transporter activity(GO:0015077)
0.0 1.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 2.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 2.7 GO:0002020 protease binding(GO:0002020)
0.0 1.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 2.4 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.6 GO:0030332 cyclin binding(GO:0030332)
0.0 1.8 GO:0005179 hormone activity(GO:0005179)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)
0.0 1.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0001972 retinoic acid binding(GO:0001972)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.5 3.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.4 4.3 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.4 3.8 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.3 8.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 12.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 4.8 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 7.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.2 10.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.2 5.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.2 3.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 5.7 PID ALK1 PATHWAY ALK1 signaling events
0.1 9.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 19.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 3.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 3.0 ST GA12 PATHWAY G alpha 12 Pathway
0.1 6.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 9.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 3.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 4.9 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 9.8 PID CDC42 PATHWAY CDC42 signaling events
0.1 3.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 1.3 PID IL5 PATHWAY IL5-mediated signaling events
0.1 2.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 1.6 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 0.8 ST ADRENERGIC Adrenergic Pathway
0.1 2.3 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 2.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 3.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 2.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 1.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 3.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 0.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 8.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.4 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 10.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.4 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.4 11.8 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.4 6.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.3 12.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.2 6.0 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.2 3.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 6.4 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.2 6.0 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.2 5.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.2 1.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 3.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 1.8 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.2 3.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.2 1.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 2.0 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 4.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 17.3 REACTOME DNA REPAIR Genes involved in DNA Repair
0.1 3.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 2.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 3.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.7 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 6.6 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 2.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.5 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 2.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 3.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.2 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 1.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 2.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 3.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 5.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 3.1 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1 11.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 2.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 1.6 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 1.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 4.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.1 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.1 2.5 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.1 1.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 6.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 3.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.8 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 1.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 2.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME PKB MEDIATED EVENTS Genes involved in PKB-mediated events