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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for KLF6

Z-value: 1.35

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Transcription factors associated with KLF6

Gene Symbol Gene ID Gene Info
KLF6
ENSG00000067082.10 Kruppel like factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF6hg19_v2_chr10_-_3827371_38273860.321.2e-06Click!

Activity profile of KLF6 motif

Sorted Z-values of KLF6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_151254738 88.98 ENST00000336715.6
ENST00000324048.5
ENST00000368879.2
ZNF687
zinc finger protein 687
chr2_+_203499901 66.41 ENST00000303116.6
ENST00000392238.2
FAM117B
family with sequence similarity 117, member B
chr14_-_21945057 60.08 ENST00000397762.1
RAB2B
RAB2B, member RAS oncogene family
chr17_-_42277203 36.47 ENST00000587097.1
ATXN7L3
ataxin 7-like 3
chr18_-_51750948 32.95 ENST00000583046.1
ENST00000398398.2
MBD2
methyl-CpG binding domain protein 2
chr1_+_156698234 28.51 ENST00000368218.4
ENST00000368216.4
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr19_+_16435625 28.34 ENST00000248071.5
ENST00000592003.1
KLF2
Kruppel-like factor 2
chr11_+_57365150 28.00 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr1_-_182361327 26.45 ENST00000331872.6
ENST00000311223.5
GLUL
glutamate-ammonia ligase
chr1_+_156698708 26.33 ENST00000519086.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr1_-_182360918 26.30 ENST00000339526.4
GLUL
glutamate-ammonia ligase
chr20_-_35492048 25.54 ENST00000237536.4
SOGA1
suppressor of glucose, autophagy associated 1
chr1_-_182360498 24.59 ENST00000417584.2
GLUL
glutamate-ammonia ligase
chr3_+_49507674 22.64 ENST00000431960.1
ENST00000452317.1
ENST00000435508.2
ENST00000452060.1
ENST00000428779.1
ENST00000419218.1
ENST00000430636.1
DAG1
dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr10_+_76586348 22.50 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
KAT6B
K(lysine) acetyltransferase 6B
chr12_+_53773944 22.26 ENST00000551969.1
ENST00000327443.4
SP1
Sp1 transcription factor
chr15_+_74422585 20.52 ENST00000561740.1
ENST00000435464.1
ENST00000453268.2
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr1_-_113615699 19.28 ENST00000421157.1
RP11-31F15.2
RP11-31F15.2
chr6_-_33285505 17.51 ENST00000431845.2
ZBTB22
zinc finger and BTB domain containing 22
chr14_-_81687197 16.59 ENST00000553612.1
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr11_+_94706973 15.42 ENST00000536741.1
KDM4D
lysine (K)-specific demethylase 4D
chr2_-_25475120 14.46 ENST00000380746.4
ENST00000402667.1
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr15_-_75744014 14.23 ENST00000394947.3
ENST00000565264.1
SIN3A
SIN3 transcription regulator family member A
chr22_+_38004832 14.01 ENST00000405147.3
ENST00000429218.1
ENST00000325180.8
ENST00000337437.4
GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr19_-_10764509 13.72 ENST00000591501.1
ILF3-AS1
ILF3 antisense RNA 1 (head to head)
chr16_-_49315731 13.43 ENST00000219197.6
CBLN1
cerebellin 1 precursor
chr14_-_81687575 13.27 ENST00000434192.2
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr2_+_70142232 13.17 ENST00000540449.1
MXD1
MAX dimerization protein 1
chr7_-_72936608 13.10 ENST00000404251.1
BAZ1B
bromodomain adjacent to zinc finger domain, 1B
chr3_+_38495333 12.86 ENST00000352511.4
ACVR2B
activin A receptor, type IIB
chr22_+_41777927 12.67 ENST00000266304.4
TEF
thyrotrophic embryonic factor
chr19_+_8455200 12.51 ENST00000601897.1
ENST00000594216.1
RAB11B
RAB11B, member RAS oncogene family
chr2_+_70142189 12.48 ENST00000264444.2
MXD1
MAX dimerization protein 1
chr6_+_72596604 12.47 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
RIMS1
regulating synaptic membrane exocytosis 1
chr1_-_236445251 12.46 ENST00000354619.5
ENST00000327333.8
ERO1LB
ERO1-like beta (S. cerevisiae)
chr10_-_124768300 12.17 ENST00000368886.5
IKZF5
IKAROS family zinc finger 5 (Pegasus)
chr18_-_72265035 12.13 ENST00000585279.1
ENST00000580048.1
LINC00909
long intergenic non-protein coding RNA 909
chr11_+_68228186 11.98 ENST00000393799.2
ENST00000393800.2
ENST00000528635.1
ENST00000533127.1
ENST00000529907.1
ENST00000529344.1
ENST00000534534.1
ENST00000524845.1
ENST00000265637.4
ENST00000524904.1
ENST00000393801.3
ENST00000265636.5
ENST00000529710.1
PPP6R3
protein phosphatase 6, regulatory subunit 3
chr11_-_2160180 11.71 ENST00000381406.4
IGF2
insulin-like growth factor 2 (somatomedin A)
chr8_-_125486755 11.57 ENST00000499418.2
ENST00000530778.1
RNF139-AS1
RNF139 antisense RNA 1 (head to head)
chr5_+_137801160 11.56 ENST00000239938.4
EGR1
early growth response 1
chr11_+_94706804 11.16 ENST00000335080.5
KDM4D
lysine (K)-specific demethylase 4D
chr10_+_102672712 11.11 ENST00000370271.3
ENST00000370269.3
ENST00000609386.1
FAM178A
family with sequence similarity 178, member A
chr17_-_27278304 11.06 ENST00000577226.1
PHF12
PHD finger protein 12
chr1_+_6845384 11.04 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr15_-_72410350 11.00 ENST00000356056.5
ENST00000424560.1
ENST00000444904.1
MYO9A
myosin IXA
chr2_+_220283091 10.92 ENST00000373960.3
DES
desmin
chr3_-_167813672 10.58 ENST00000470487.1
GOLIM4
golgi integral membrane protein 4
chr2_+_105471969 10.22 ENST00000361360.2
POU3F3
POU class 3 homeobox 3
chr22_+_38004473 10.06 ENST00000414350.3
ENST00000343632.4
GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr10_+_124768482 10.01 ENST00000368869.4
ENST00000358776.4
ACADSB
acyl-CoA dehydrogenase, short/branched chain
chr14_-_50698276 10.00 ENST00000216373.5
SOS2
son of sevenless homolog 2 (Drosophila)
chr17_+_36508111 9.93 ENST00000331159.5
ENST00000577233.1
SOCS7
suppressor of cytokine signaling 7
chr10_-_75634219 9.81 ENST00000305762.7
CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
chr1_-_38512450 9.61 ENST00000373012.2
POU3F1
POU class 3 homeobox 1
chr3_-_167813132 9.48 ENST00000309027.4
GOLIM4
golgi integral membrane protein 4
chr11_+_117070037 9.41 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
TAGLN
transgelin
chr4_-_76598326 9.15 ENST00000503660.1
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr8_-_33424636 8.99 ENST00000256257.1
RNF122
ring finger protein 122
chr20_-_524362 8.93 ENST00000460062.2
ENST00000608066.1
CSNK2A1
casein kinase 2, alpha 1 polypeptide
chr7_-_143105941 8.92 ENST00000275815.3
EPHA1
EPH receptor A1
chr17_-_42276574 8.88 ENST00000589805.1
ATXN7L3
ataxin 7-like 3
chr19_-_5978144 8.76 ENST00000340578.6
ENST00000541471.1
ENST00000591736.1
ENST00000587479.1
RANBP3
RAN binding protein 3
chr2_-_30144432 8.43 ENST00000389048.3
ALK
anaplastic lymphoma receptor tyrosine kinase
chr19_-_5978090 8.22 ENST00000592621.1
ENST00000034275.8
ENST00000591092.1
ENST00000591333.1
ENST00000590623.1
ENST00000439268.2
ENST00000587159.1
RANBP3
RAN binding protein 3
chr10_+_104474207 8.19 ENST00000602831.1
ENST00000369893.5
SFXN2
sideroflexin 2
chr1_+_207226574 8.07 ENST00000367080.3
ENST00000367079.2
PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr3_-_53080047 8.05 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
SFMBT1
Scm-like with four mbt domains 1
chr6_+_83777374 8.05 ENST00000349129.2
ENST00000237163.5
ENST00000536812.1
DOPEY1
dopey family member 1
chr15_-_75743991 7.84 ENST00000567289.1
SIN3A
SIN3 transcription regulator family member A
chr4_-_174451370 7.80 ENST00000359562.4
HAND2
heart and neural crest derivatives expressed 2
chr3_-_50540854 7.70 ENST00000423994.2
ENST00000424201.2
ENST00000479441.1
ENST00000429770.1
CACNA2D2
calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr11_-_3862059 7.68 ENST00000396978.1
RHOG
ras homolog family member G
chr12_+_52445191 7.64 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr15_+_43803143 7.59 ENST00000382031.1
MAP1A
microtubule-associated protein 1A
chr14_+_58765103 7.55 ENST00000355431.3
ENST00000348476.3
ENST00000395168.3
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr6_+_37137939 7.53 ENST00000373509.5
PIM1
pim-1 oncogene
chr11_+_45868957 7.52 ENST00000443527.2
CRY2
cryptochrome 2 (photolyase-like)
chr2_+_219433281 7.41 ENST00000273064.6
ENST00000509807.2
ENST00000542068.1
RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr11_-_62521614 7.37 ENST00000527994.1
ENST00000394807.3
ZBTB3
zinc finger and BTB domain containing 3
chr9_+_35605274 7.30 ENST00000336395.5
TESK1
testis-specific kinase 1
chr11_-_133826852 7.29 ENST00000533871.2
ENST00000321016.8
IGSF9B
immunoglobulin superfamily, member 9B
chr19_+_54372639 7.27 ENST00000391769.2
MYADM
myeloid-associated differentiation marker
chr2_-_71454185 7.20 ENST00000244221.8
PAIP2B
poly(A) binding protein interacting protein 2B
chr12_+_10365404 7.14 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr10_-_101380121 7.08 ENST00000370495.4
SLC25A28
solute carrier family 25 (mitochondrial iron transporter), member 28
chr17_-_74449252 7.04 ENST00000319380.7
UBE2O
ubiquitin-conjugating enzyme E2O
chr19_-_46000251 7.00 ENST00000590526.1
ENST00000344680.4
ENST00000245923.4
RTN2
reticulon 2
chr5_-_159739532 6.75 ENST00000520748.1
ENST00000393977.3
ENST00000257536.7
CCNJL
cyclin J-like
chr5_+_34929677 6.75 ENST00000342382.4
ENST00000382021.2
ENST00000303525.7
DNAJC21
DnaJ (Hsp40) homolog, subfamily C, member 21
chr22_+_38005033 6.74 ENST00000447515.1
ENST00000406772.1
ENST00000431745.1
GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr6_-_31125850 6.67 ENST00000507751.1
ENST00000448162.2
ENST00000502557.1
ENST00000503420.1
ENST00000507892.1
ENST00000507226.1
ENST00000513222.1
ENST00000503934.1
ENST00000396263.2
ENST00000508683.1
ENST00000428174.1
ENST00000448141.2
ENST00000507829.1
ENST00000455279.2
ENST00000376266.5
CCHCR1
coiled-coil alpha-helical rod protein 1
chr17_+_73452695 6.66 ENST00000582186.1
ENST00000582455.1
ENST00000581252.1
ENST00000579208.1
KIAA0195
KIAA0195
chrX_+_48660287 6.62 ENST00000444343.2
ENST00000376610.2
ENST00000334136.5
ENST00000376619.2
HDAC6
histone deacetylase 6
chr9_+_34989638 6.59 ENST00000453597.3
ENST00000335998.3
ENST00000312316.5
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr12_+_70132632 6.56 ENST00000378815.6
ENST00000483530.2
ENST00000325555.9
RAB3IP
RAB3A interacting protein
chr12_-_7125770 6.56 ENST00000261407.4
LPCAT3
lysophosphatidylcholine acyltransferase 3
chr10_+_50818343 6.55 ENST00000374115.3
SLC18A3
solute carrier family 18 (vesicular acetylcholine transporter), member 3
chr11_-_119234876 6.48 ENST00000525735.1
USP2
ubiquitin specific peptidase 2
chr2_+_111878483 6.45 ENST00000308659.8
ENST00000357757.2
ENST00000393253.2
ENST00000337565.5
ENST00000393256.3
BCL2L11
BCL2-like 11 (apoptosis facilitator)
chr5_+_149109825 6.43 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr7_+_86781847 6.41 ENST00000432366.2
ENST00000423590.2
ENST00000394703.5
DMTF1
cyclin D binding myb-like transcription factor 1
chr11_-_62494821 6.36 ENST00000301785.5
HNRNPUL2
heterogeneous nuclear ribonucleoprotein U-like 2
chr14_-_82000140 6.36 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
SEL1L
sel-1 suppressor of lin-12-like (C. elegans)
chr4_+_159593271 6.35 ENST00000512251.1
ENST00000511912.1
ETFDH
electron-transferring-flavoprotein dehydrogenase
chr3_-_49907323 6.33 ENST00000296471.7
ENST00000488336.1
ENST00000467248.1
ENST00000466940.1
ENST00000463537.1
ENST00000480398.2
CAMKV
CaM kinase-like vesicle-associated
chr19_-_14117074 6.31 ENST00000588885.1
ENST00000254325.4
RFX1
regulatory factor X, 1 (influences HLA class II expression)
chr17_-_7120498 6.31 ENST00000485100.1
DLG4
discs, large homolog 4 (Drosophila)
chr15_-_72410109 6.28 ENST00000564571.1
MYO9A
myosin IXA
chr6_+_71122974 6.19 ENST00000418814.2
FAM135A
family with sequence similarity 135, member A
chr12_+_57482665 6.19 ENST00000300131.3
NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr7_+_86781677 6.18 ENST00000331242.7
ENST00000394702.3
ENST00000413276.2
ENST00000446796.2
ENST00000411766.2
ENST00000420131.1
ENST00000414630.2
ENST00000453049.1
ENST00000428819.1
ENST00000448598.1
ENST00000449088.3
ENST00000430405.3
DMTF1
cyclin D binding myb-like transcription factor 1
chr10_-_75634260 6.12 ENST00000372765.1
ENST00000351293.3
CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
chr14_+_94640671 6.10 ENST00000328839.3
PPP4R4
protein phosphatase 4, regulatory subunit 4
chr7_+_116593292 6.09 ENST00000393446.2
ENST00000265437.5
ENST00000393451.3
ST7
suppression of tumorigenicity 7
chr6_-_94129244 6.04 ENST00000369303.4
ENST00000369297.1
EPHA7
EPH receptor A7
chr10_+_99258625 6.02 ENST00000370664.3
UBTD1
ubiquitin domain containing 1
chr1_-_156698591 6.00 ENST00000368219.1
ISG20L2
interferon stimulated exonuclease gene 20kDa-like 2
chr3_+_50192537 5.98 ENST00000002829.3
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr14_-_92572894 5.98 ENST00000532032.1
ENST00000506466.1
ENST00000555381.1
ENST00000557311.1
ENST00000554592.1
ENST00000554672.1
ENST00000553491.1
ENST00000556220.1
ENST00000502250.1
ENST00000503767.1
ENST00000393287.5
ENST00000340660.6
ENST00000545170.1
ENST00000429774.2
ATXN3
ataxin 3
chr15_+_41136216 5.89 ENST00000562057.1
ENST00000344051.4
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr21_+_43639211 5.89 ENST00000450121.1
ENST00000398449.3
ENST00000361802.2
ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr10_+_45869652 5.81 ENST00000542434.1
ENST00000374391.2
ALOX5
arachidonate 5-lipoxygenase
chrX_-_49056635 5.79 ENST00000472598.1
ENST00000538567.1
ENST00000479808.1
ENST00000263233.4
SYP
synaptophysin
chr2_+_61404624 5.78 ENST00000394457.3
AHSA2
AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast)
chr19_+_10400615 5.78 ENST00000221980.4
ICAM5
intercellular adhesion molecule 5, telencephalin
chr4_-_36246060 5.77 ENST00000303965.4
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_+_42264322 5.77 ENST00000446571.3
ENST00000357984.3
ENST00000538716.2
TMUB2
transmembrane and ubiquitin-like domain containing 2
chr19_+_54641444 5.76 ENST00000221232.5
ENST00000358389.3
CNOT3
CCR4-NOT transcription complex, subunit 3
chr17_-_36956155 5.69 ENST00000269554.3
PIP4K2B
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr14_+_94640633 5.67 ENST00000304338.3
PPP4R4
protein phosphatase 4, regulatory subunit 4
chr3_+_49449636 5.67 ENST00000273590.3
TCTA
T-cell leukemia translocation altered
chr7_+_96634850 5.66 ENST00000518156.2
DLX6
distal-less homeobox 6
chr13_+_28712614 5.66 ENST00000380958.3
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr22_+_32149927 5.63 ENST00000437411.1
ENST00000535622.1
ENST00000536766.1
ENST00000400242.3
ENST00000266091.3
ENST00000400249.2
ENST00000400246.1
ENST00000382105.2
DEPDC5
DEP domain containing 5
chr16_-_68482440 5.60 ENST00000219334.5
SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr12_+_57610562 5.60 ENST00000349394.5
NXPH4
neurexophilin 4
chr5_-_134871639 5.58 ENST00000314744.4
NEUROG1
neurogenin 1
chr1_-_204121102 5.52 ENST00000367202.4
ETNK2
ethanolamine kinase 2
chr19_-_40791211 5.49 ENST00000579047.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr12_-_120554622 5.43 ENST00000229340.5
RAB35
RAB35, member RAS oncogene family
chr19_+_36545833 5.41 ENST00000401500.2
ENST00000270301.7
ENST00000427823.2
WDR62
WD repeat domain 62
chr8_+_28196157 5.37 ENST00000522209.1
PNOC
prepronociceptin
chr1_+_114522049 5.34 ENST00000369551.1
ENST00000320334.4
OLFML3
olfactomedin-like 3
chr19_-_15311713 5.31 ENST00000601011.1
ENST00000263388.2
NOTCH3
notch 3
chr10_+_112836779 5.31 ENST00000280155.2
ADRA2A
adrenoceptor alpha 2A
chr5_+_56111361 5.30 ENST00000399503.3
MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr2_+_64751433 5.26 ENST00000238856.4
ENST00000422803.1
ENST00000238855.7
AFTPH
aftiphilin
chr15_+_41136586 5.25 ENST00000431806.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr15_-_53082178 5.22 ENST00000305901.5
ONECUT1
one cut homeobox 1
chr16_+_69600209 5.21 ENST00000566899.1
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr17_-_58469474 5.20 ENST00000300896.4
USP32
ubiquitin specific peptidase 32
chr15_-_66084428 5.15 ENST00000443035.3
ENST00000431932.2
DENND4A
DENN/MADD domain containing 4A
chr12_-_51611477 5.15 ENST00000389243.4
POU6F1
POU class 6 homeobox 1
chr4_+_155665123 5.14 ENST00000336356.3
LRAT
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr17_+_61554413 5.14 ENST00000538928.1
ENST00000290866.4
ENST00000428043.1
ACE
angiotensin I converting enzyme
chr17_+_42264395 5.14 ENST00000587989.1
ENST00000590235.1
TMUB2
transmembrane and ubiquitin-like domain containing 2
chr6_-_150039249 5.13 ENST00000543571.1
LATS1
large tumor suppressor kinase 1
chr16_+_67465016 5.11 ENST00000326152.5
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr15_-_83316254 5.11 ENST00000567678.1
ENST00000450751.2
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr17_+_42264556 5.11 ENST00000319511.6
ENST00000589785.1
ENST00000592825.1
ENST00000589184.1
TMUB2
transmembrane and ubiquitin-like domain containing 2
chr5_-_81046904 5.09 ENST00000515395.1
SSBP2
single-stranded DNA binding protein 2
chr11_-_19262486 5.05 ENST00000250024.4
E2F8
E2F transcription factor 8
chr1_+_113615794 5.05 ENST00000361127.5
LRIG2
leucine-rich repeats and immunoglobulin-like domains 2
chr20_-_35724388 5.04 ENST00000344359.3
ENST00000373664.3
RBL1
retinoblastoma-like 1 (p107)
chr3_+_50192499 5.01 ENST00000413852.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr2_-_220408430 5.00 ENST00000243776.6
CHPF
chondroitin polymerizing factor
chr1_+_21835858 4.96 ENST00000539907.1
ENST00000540617.1
ENST00000374840.3
ALPL
alkaline phosphatase, liver/bone/kidney
chr2_+_219724544 4.94 ENST00000233948.3
WNT6
wingless-type MMTV integration site family, member 6
chr11_+_64851729 4.92 ENST00000526791.1
ENST00000526945.1
ZFPL1
zinc finger protein-like 1
chr14_-_65346555 4.87 ENST00000542895.1
ENST00000556626.1
SPTB
spectrin, beta, erythrocytic
chr12_+_9067123 4.86 ENST00000543824.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr4_+_6202448 4.85 ENST00000508601.1
RP11-586D19.1
RP11-586D19.1
chr17_-_1389228 4.84 ENST00000438665.2
MYO1C
myosin IC
chr17_-_8066250 4.82 ENST00000488857.1
ENST00000481878.1
ENST00000316509.6
ENST00000498285.1
VAMP2
RP11-599B13.6
vesicle-associated membrane protein 2 (synaptobrevin 2)
Uncharacterized protein
chr9_-_37465396 4.81 ENST00000307750.4
ZBTB5
zinc finger and BTB domain containing 5
chr12_+_70760056 4.80 ENST00000258111.4
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr20_+_57875658 4.80 ENST00000371025.3
EDN3
endothelin 3
chr17_-_47841485 4.79 ENST00000506156.1
ENST00000240364.2
FAM117A
family with sequence similarity 117, member A
chr4_-_153456153 4.68 ENST00000603548.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr19_+_42724423 4.65 ENST00000301215.3
ENST00000597945.1
ZNF526
zinc finger protein 526
chr1_-_113498616 4.64 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr3_-_184079382 4.63 ENST00000344937.7
ENST00000423355.2
ENST00000434054.2
ENST00000457512.1
ENST00000265593.4
CLCN2
chloride channel, voltage-sensitive 2
chrY_-_25345070 4.62 ENST00000382510.4
ENST00000426000.2
ENST00000540248.1
ENST00000405239.1
DAZ1
deleted in azoospermia 1
chr5_+_40679584 4.58 ENST00000302472.3
PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr17_+_47572647 4.56 ENST00000172229.3
NGFR
nerve growth factor receptor
chr7_+_106685079 4.53 ENST00000265717.4
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr6_+_35227449 4.47 ENST00000373953.3
ENST00000440666.2
ENST00000339411.5
ZNF76
zinc finger protein 76
chr3_-_135914615 4.46 ENST00000309993.2
MSL2
male-specific lethal 2 homolog (Drosophila)
chr11_-_66445219 4.45 ENST00000525754.1
ENST00000531969.1
ENST00000524637.1
ENST00000531036.2
ENST00000310046.4
RBM4B
RNA binding motif protein 4B
chr6_+_72596406 4.45 ENST00000491071.2
RIMS1
regulating synaptic membrane exocytosis 1
chr17_+_43299156 4.44 ENST00000331495.3
FMNL1
formin-like 1
chr16_+_69600058 4.41 ENST00000393742.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr7_+_128828713 4.40 ENST00000249373.3
SMO
smoothened, frizzled family receptor
chr2_-_114514181 4.39 ENST00000409342.1
SLC35F5
solute carrier family 35, member F5
chr9_+_100174344 4.38 ENST00000422139.2
TDRD7
tudor domain containing 7
chr3_-_170626418 4.36 ENST00000474096.1
ENST00000295822.2
EIF5A2
eukaryotic translation initiation factor 5A2
chr11_-_113345842 4.35 ENST00000346454.3
DRD2
dopamine receptor D2
chr1_+_160336851 4.35 ENST00000302101.5
NHLH1
nescient helix loop helix 1
chr5_-_148033726 4.33 ENST00000354217.2
ENST00000314512.6
ENST00000362016.2
HTR4
5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
19.3 77.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
11.6 11.6 GO:0071505 response to mycophenolic acid(GO:0071505) cellular response to mycophenolic acid(GO:0071506)
9.4 28.3 GO:0071409 cellular response to cycloheximide(GO:0071409)
7.4 22.1 GO:0051595 response to methylglyoxal(GO:0051595)
5.3 26.6 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
4.4 22.0 GO:0016476 regulation of embryonic cell shape(GO:0016476)
4.1 24.6 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
3.3 16.6 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
3.2 6.5 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
3.1 12.3 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
2.7 54.8 GO:0031167 rRNA methylation(GO:0031167)
2.6 40.8 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
2.5 7.5 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
2.4 17.0 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
2.4 7.1 GO:0048250 mitochondrial iron ion transport(GO:0048250)
2.3 11.4 GO:0003219 cardiac right ventricle formation(GO:0003219)
2.2 6.6 GO:0090035 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
2.2 28.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
2.1 8.4 GO:0036269 swimming behavior(GO:0036269)
2.0 10.2 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
1.9 7.5 GO:0097368 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
1.8 7.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
1.8 5.3 GO:0035625 epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
1.8 28.0 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
1.7 5.0 GO:0071529 cementum mineralization(GO:0071529)
1.6 6.5 GO:0035879 plasma membrane lactate transport(GO:0035879)
1.6 45.6 GO:0016578 histone deubiquitination(GO:0016578)
1.6 4.9 GO:0016574 histone ubiquitination(GO:0016574)
1.6 8.1 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
1.6 1.6 GO:0035803 egg coat formation(GO:0035803)
1.5 7.7 GO:0060024 rhythmic synaptic transmission(GO:0060024)
1.5 4.6 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
1.5 6.0 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
1.5 5.9 GO:0055099 response to high density lipoprotein particle(GO:0055099)
1.5 10.3 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
1.5 11.7 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
1.4 14.2 GO:0045054 constitutive secretory pathway(GO:0045054)
1.4 5.7 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
1.4 4.1 GO:0045925 positive regulation of female receptivity(GO:0045925)
1.4 6.9 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
1.4 11.0 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
1.4 9.6 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
1.3 24.2 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
1.3 3.9 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
1.3 5.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
1.3 2.6 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
1.3 3.9 GO:0021648 vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve formation(GO:0021650)
1.3 5.1 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
1.3 3.8 GO:0014043 negative regulation of neuron maturation(GO:0014043)
1.3 7.6 GO:0051799 negative regulation of hair follicle development(GO:0051799)
1.2 3.7 GO:0015743 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
1.2 2.5 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
1.2 1.2 GO:0009954 proximal/distal pattern formation(GO:0009954)
1.2 12.9 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
1.2 4.7 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
1.2 3.5 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
1.2 4.6 GO:0060010 Sertoli cell fate commitment(GO:0060010)
1.1 4.5 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
1.1 4.4 GO:0044467 glial cell-derived neurotrophic factor secretion(GO:0044467) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
1.1 4.3 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
1.1 4.2 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
1.0 19.7 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
1.0 5.1 GO:0001826 inner cell mass cell differentiation(GO:0001826)
1.0 9.2 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
1.0 8.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
1.0 3.0 GO:0060592 mammary gland formation(GO:0060592)
1.0 3.0 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
1.0 3.0 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
1.0 3.0 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
1.0 3.0 GO:0021558 trochlear nerve development(GO:0021558)
0.9 4.7 GO:0010868 negative regulation of triglyceride biosynthetic process(GO:0010868) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.9 6.5 GO:0015870 acetylcholine transport(GO:0015870)
0.9 6.4 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.9 5.5 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.9 4.6 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.9 7.3 GO:0043320 natural killer cell degranulation(GO:0043320)
0.9 4.5 GO:0097338 response to clozapine(GO:0097338)
0.8 7.6 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.8 4.9 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.8 1.6 GO:0008050 female courtship behavior(GO:0008050)
0.8 2.4 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.8 5.7 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.8 4.8 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.8 4.0 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.8 2.4 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.8 9.9 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.8 5.3 GO:0072104 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.7 2.2 GO:1902227 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.7 5.1 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.7 5.8 GO:0007258 JUN phosphorylation(GO:0007258)
0.7 3.5 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.7 5.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.7 4.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.7 2.0 GO:1904395 positive regulation of postsynaptic membrane organization(GO:1901628) positive regulation of presynaptic membrane organization(GO:1901631) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.7 2.0 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.7 11.1 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.7 2.0 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.6 5.8 GO:2001300 lipoxin metabolic process(GO:2001300)
0.6 3.2 GO:0000189 MAPK import into nucleus(GO:0000189)
0.6 5.8 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.6 7.0 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.6 61.1 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.6 1.8 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.6 3.0 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.6 6.0 GO:0048755 branching morphogenesis of a nerve(GO:0048755) nephric duct morphogenesis(GO:0072178)
0.6 4.7 GO:0090166 Golgi disassembly(GO:0090166) spindle assembly involved in meiosis(GO:0090306)
0.6 5.8 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.6 4.0 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.6 5.1 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.5 4.4 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.5 17.4 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.5 22.2 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.5 7.6 GO:0038092 nodal signaling pathway(GO:0038092)
0.5 1.1 GO:1904693 midbrain morphogenesis(GO:1904693)
0.5 2.7 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.5 1.6 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.5 7.8 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.5 1.5 GO:0044805 late nucleophagy(GO:0044805)
0.5 3.0 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.5 10.9 GO:0045109 intermediate filament organization(GO:0045109)
0.5 5.7 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.5 4.6 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.5 1.8 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.5 3.6 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.5 1.4 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.4 1.3 GO:1900158 negative regulation of osteoclast proliferation(GO:0090291) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.4 2.7 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.4 3.5 GO:0006013 mannose metabolic process(GO:0006013)
0.4 11.9 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.4 2.6 GO:0051013 microtubule severing(GO:0051013)
0.4 6.5 GO:0045475 locomotor rhythm(GO:0045475)
0.4 5.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.4 6.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.4 3.3 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.4 2.4 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.4 4.3 GO:0015871 choline transport(GO:0015871)
0.4 2.7 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.4 5.7 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.4 4.8 GO:0005513 detection of calcium ion(GO:0005513)
0.4 28.0 GO:0043966 histone H3 acetylation(GO:0043966)
0.4 2.2 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.4 7.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.4 2.5 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.3 8.0 GO:0006895 Golgi to endosome transport(GO:0006895)
0.3 4.2 GO:0016180 snRNA processing(GO:0016180)
0.3 1.0 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.3 3.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.3 9.4 GO:0032456 endocytic recycling(GO:0032456)
0.3 1.9 GO:0070459 prolactin secretion(GO:0070459)
0.3 7.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.3 5.8 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.3 5.7 GO:0051014 actin filament severing(GO:0051014)
0.3 5.1 GO:0032094 response to food(GO:0032094)
0.3 2.6 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.3 8.0 GO:0032098 regulation of appetite(GO:0032098)
0.3 6.6 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.3 5.6 GO:0030517 negative regulation of axon extension(GO:0030517)
0.3 1.9 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.3 5.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.3 6.2 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.3 3.5 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.3 1.9 GO:0060068 vagina development(GO:0060068)
0.3 19.0 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.2 3.7 GO:0070914 UV-damage excision repair(GO:0070914)
0.2 1.0 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.2 2.9 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 3.0 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.2 3.8 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.2 3.9 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.2 4.5 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.2 8.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.2 6.6 GO:0006986 response to unfolded protein(GO:0006986)
0.2 3.9 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.2 1.1 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2 8.9 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.2 8.8 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.2 1.4 GO:0089700 protein kinase D signaling(GO:0089700)
0.2 4.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.2 4.8 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.2 1.2 GO:0060157 urinary bladder development(GO:0060157)
0.2 2.9 GO:0060736 prostate gland growth(GO:0060736)
0.2 0.6 GO:0006014 D-ribose metabolic process(GO:0006014)
0.2 3.7 GO:0021854 hypothalamus development(GO:0021854)
0.2 8.3 GO:1901998 toxin transport(GO:1901998)
0.2 4.6 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.2 1.3 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.2 8.9 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.2 7.5 GO:0051057 positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.2 3.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.2 5.2 GO:0048536 spleen development(GO:0048536)
0.2 7.9 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.2 2.5 GO:0006020 inositol metabolic process(GO:0006020)
0.2 6.4 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.2 5.4 GO:0007099 centriole replication(GO:0007099)
0.2 0.9 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.2 2.5 GO:0045116 protein neddylation(GO:0045116)
0.2 11.0 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.2 3.3 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.1 2.5 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 5.3 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.1 3.4 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 2.4 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.1 4.4 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 1.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 2.3 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 1.7 GO:0034378 chylomicron assembly(GO:0034378)
0.1 2.0 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 1.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.5 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 2.1 GO:0042461 photoreceptor cell development(GO:0042461)
0.1 7.6 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.1 1.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 2.2 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 1.1 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 0.6 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 3.5 GO:0060612 adipose tissue development(GO:0060612)
0.1 6.9 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 21.6 GO:0007601 visual perception(GO:0007601) sensory perception of light stimulus(GO:0050953)
0.1 1.2 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.1 5.0 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.1 0.5 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 1.2 GO:0048596 embryonic camera-type eye morphogenesis(GO:0048596)
0.1 0.6 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 2.2 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 1.5 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.1 5.4 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 4.6 GO:0065002 intracellular protein transmembrane transport(GO:0065002)
0.1 0.9 GO:0006558 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1 1.3 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.5 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 1.8 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 0.6 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1 0.3 GO:0042756 drinking behavior(GO:0042756)
0.1 1.5 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210)
0.1 0.6 GO:0021544 grooming behavior(GO:0007625) subpallium development(GO:0021544) striatum development(GO:0021756)
0.1 2.6 GO:0001523 retinoid metabolic process(GO:0001523)
0.0 3.1 GO:0007588 excretion(GO:0007588)
0.0 0.4 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 2.1 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 1.8 GO:0045453 bone resorption(GO:0045453)
0.0 1.9 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.0 1.7 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 1.4 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 2.1 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 1.0 GO:0007050 cell cycle arrest(GO:0007050)
0.0 4.1 GO:0007018 microtubule-based movement(GO:0007018)
0.0 1.9 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.4 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.0 1.2 GO:0030193 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0 1.5 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 6.8 GO:0051607 defense response to virus(GO:0051607)
0.0 3.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 3.2 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 0.7 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.1 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.3 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.1 GO:0060033 anatomical structure regression(GO:0060033)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 77.3 GO:0097386 glial cell projection(GO:0097386)
3.7 29.9 GO:0005672 transcription factor TFIIA complex(GO:0005672)
3.0 45.4 GO:0000124 SAGA complex(GO:0000124)
2.7 26.6 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
2.2 22.0 GO:0070938 dystroglycan complex(GO:0016011) contractile ring(GO:0070938)
1.9 5.7 GO:0031251 PAN complex(GO:0031251)
1.8 3.5 GO:0005797 Golgi medial cisterna(GO:0005797)
1.7 5.1 GO:0060187 cell pole(GO:0060187)
1.7 11.8 GO:0030121 AP-1 adaptor complex(GO:0030121)
1.5 7.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.5 10.3 GO:0000137 Golgi cis cisterna(GO:0000137)
1.4 22.1 GO:0016461 unconventional myosin complex(GO:0016461)
1.3 6.4 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
1.3 7.6 GO:1990769 proximal neuron projection(GO:1990769)
1.2 4.8 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
1.1 10.3 GO:0098839 postsynaptic density membrane(GO:0098839)
1.0 4.0 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
1.0 3.9 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
1.0 14.5 GO:0001741 XY body(GO:0001741)
0.9 5.6 GO:1990130 Iml1 complex(GO:1990130)
0.9 25.1 GO:0035861 site of double-strand break(GO:0035861)
0.9 2.7 GO:0005960 glycine cleavage complex(GO:0005960)
0.9 7.0 GO:0014802 terminal cisterna(GO:0014802)
0.8 33.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.8 3.3 GO:0055087 Ski complex(GO:0055087)
0.8 5.0 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.8 11.3 GO:0005916 fascia adherens(GO:0005916)
0.7 5.8 GO:0044294 dendritic growth cone(GO:0044294)
0.7 4.7 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.6 7.3 GO:0060077 inhibitory synapse(GO:0060077)
0.6 13.4 GO:0016580 Sin3 complex(GO:0016580)
0.6 5.8 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.6 25.9 GO:0048786 presynaptic active zone(GO:0048786)
0.5 6.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.5 32.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.5 3.3 GO:0031143 pseudopodium(GO:0031143)
0.5 4.2 GO:0032039 integrator complex(GO:0032039)
0.4 1.8 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.4 28.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.4 4.4 GO:0033391 chromatoid body(GO:0033391)
0.4 20.2 GO:0005801 cis-Golgi network(GO:0005801)
0.3 3.5 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.3 4.9 GO:0035102 PRC1 complex(GO:0035102)
0.3 5.7 GO:0032059 bleb(GO:0032059)
0.3 15.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.3 3.1 GO:0002080 acrosomal membrane(GO:0002080)
0.3 8.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.3 2.0 GO:0072487 MSL complex(GO:0072487)
0.3 2.3 GO:0035253 ciliary rootlet(GO:0035253)
0.3 32.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.3 13.1 GO:0043198 dendritic shaft(GO:0043198)
0.3 2.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.3 4.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.3 2.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.3 7.1 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.2 2.2 GO:0030137 COPI-coated vesicle(GO:0030137)
0.2 6.3 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.2 12.5 GO:0045171 intercellular bridge(GO:0045171)
0.2 1.9 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 2.6 GO:0000815 ESCRT III complex(GO:0000815)
0.2 9.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 2.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 5.4 GO:0071011 precatalytic spliceosome(GO:0071011)
0.2 48.1 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.2 3.5 GO:0046930 pore complex(GO:0046930)
0.1 14.4 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 0.4 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 2.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 2.0 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 3.1 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 1.7 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 2.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 4.1 GO:0005844 polysome(GO:0005844)
0.1 4.4 GO:0097542 ciliary tip(GO:0097542)
0.1 0.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 4.1 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.1 10.2 GO:0005814 centriole(GO:0005814)
0.1 7.3 GO:0031594 neuromuscular junction(GO:0031594)
0.1 2.5 GO:0030658 transport vesicle membrane(GO:0030658)
0.1 4.1 GO:0005871 kinesin complex(GO:0005871)
0.1 10.5 GO:0005796 Golgi lumen(GO:0005796)
0.1 2.7 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 3.9 GO:0016235 aggresome(GO:0016235)
0.1 9.9 GO:0043204 perikaryon(GO:0043204)
0.1 2.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 5.5 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.6 GO:0097433 dense body(GO:0097433)
0.1 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 4.6 GO:0034707 chloride channel complex(GO:0034707)
0.1 3.0 GO:0042734 presynaptic membrane(GO:0042734)
0.1 3.0 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 23.1 GO:0043235 receptor complex(GO:0043235)
0.1 20.3 GO:0000790 nuclear chromatin(GO:0000790)
0.1 9.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 6.9 GO:0008021 synaptic vesicle(GO:0008021)
0.1 1.9 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 1.9 GO:0030175 filopodium(GO:0030175)
0.0 4.3 GO:0098793 presynapse(GO:0098793)
0.0 4.2 GO:0005643 nuclear pore(GO:0005643)
0.0 1.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 2.0 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 1.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 2.5 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 2.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.8 GO:0031941 filamentous actin(GO:0031941)
0.0 86.1 GO:0016021 integral component of membrane(GO:0016021)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 1.3 GO:0016459 myosin complex(GO:0016459)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
19.3 77.3 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
11.0 54.8 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
3.7 22.0 GO:0043237 laminin-1 binding(GO:0043237)
3.4 10.3 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
2.7 27.4 GO:0003696 satellite DNA binding(GO:0003696)
2.5 7.4 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
2.5 12.3 GO:0031708 endothelin B receptor binding(GO:0031708)
2.3 11.6 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
2.0 5.9 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
1.9 30.8 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
1.9 5.7 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
1.9 5.6 GO:0070888 E-box binding(GO:0070888)
1.8 12.9 GO:0017002 activin-activated receptor activity(GO:0017002)
1.8 5.3 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
1.7 5.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
1.7 5.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
1.7 71.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
1.7 6.6 GO:0042903 tubulin deacetylase activity(GO:0042903)
1.6 6.5 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
1.6 8.0 GO:0001594 trace-amine receptor activity(GO:0001594)
1.3 8.1 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
1.3 6.6 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
1.3 5.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
1.3 24.7 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
1.3 3.8 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
1.2 3.7 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
1.2 8.4 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
1.2 9.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
1.2 3.5 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
1.1 12.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
1.1 5.4 GO:0070097 delta-catenin binding(GO:0070097)
1.1 4.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
1.1 17.0 GO:0045499 chemorepellent activity(GO:0045499)
1.1 6.3 GO:0048039 ubiquinone binding(GO:0048039)
1.0 20.7 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.9 5.7 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.9 4.7 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.9 6.4 GO:0050682 AF-2 domain binding(GO:0050682)
0.9 3.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.9 5.1 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
0.9 5.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.8 4.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.8 5.4 GO:0001515 opioid peptide activity(GO:0001515)
0.7 2.2 GO:0097677 STAT family protein binding(GO:0097677)
0.7 11.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.7 47.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.7 5.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.7 6.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.7 5.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.7 5.0 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.7 4.6 GO:0048406 nerve growth factor binding(GO:0048406)
0.7 7.8 GO:0003680 AT DNA binding(GO:0003680)
0.6 1.9 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.6 4.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.6 4.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.6 5.5 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.6 3.0 GO:0061665 SUMO ligase activity(GO:0061665)
0.6 3.0 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.6 6.0 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.6 26.0 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.6 4.7 GO:0050816 phosphothreonine binding(GO:0050816)
0.6 7.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.6 12.6 GO:0071837 HMG box domain binding(GO:0071837)
0.6 4.6 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.6 2.2 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.6 5.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.5 7.1 GO:0030957 Tat protein binding(GO:0030957)
0.5 2.7 GO:0008420 CTD phosphatase activity(GO:0008420)
0.5 3.0 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.5 2.5 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.5 5.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.4 2.7 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.4 7.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.4 6.6 GO:0009881 photoreceptor activity(GO:0009881)
0.4 3.9 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.4 3.5 GO:0097322 7SK snRNA binding(GO:0097322)
0.4 2.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.4 4.7 GO:0051434 BH3 domain binding(GO:0051434)
0.4 9.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.4 4.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.4 1.6 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.4 19.3 GO:0070412 R-SMAD binding(GO:0070412)
0.4 15.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.4 4.0 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.4 5.7 GO:0032794 GTPase activating protein binding(GO:0032794)
0.4 5.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.4 27.5 GO:0019003 GDP binding(GO:0019003)
0.4 18.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.3 4.7 GO:0019789 SUMO transferase activity(GO:0019789)
0.3 35.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 1.0 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.3 4.2 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.3 7.6 GO:0050699 WW domain binding(GO:0050699)
0.3 4.8 GO:0017160 Ral GTPase binding(GO:0017160)
0.3 9.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.3 7.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.3 4.6 GO:0090079 translation regulator activity, nucleic acid binding(GO:0090079)
0.3 1.3 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.3 15.2 GO:0043621 protein self-association(GO:0043621)
0.3 1.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.3 1.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.3 4.8 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.2 15.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.2 2.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 0.9 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.2 4.5 GO:0008603 cAMP-dependent protein kinase inhibitor activity(GO:0004862) cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 5.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 6.3 GO:0070840 dynein complex binding(GO:0070840)
0.2 4.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 14.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.2 3.7 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.2 2.0 GO:0019826 oxygen sensor activity(GO:0019826)
0.2 2.7 GO:0016594 glycine binding(GO:0016594)
0.2 6.9 GO:0030332 cyclin binding(GO:0030332)
0.2 0.5 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 5.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 5.8 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.2 3.7 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.2 5.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 2.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 1.5 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.2 1.6 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 4.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 21.4 GO:0003774 motor activity(GO:0003774)
0.2 0.9 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 6.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 3.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 1.9 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 9.8 GO:0030276 clathrin binding(GO:0030276)
0.1 0.4 GO:0070984 SET domain binding(GO:0070984)
0.1 19.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 4.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 5.1 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 2.2 GO:0004697 protein kinase C activity(GO:0004697)
0.1 1.2 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 1.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 10.0 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.1 1.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 2.0 GO:0031005 filamin binding(GO:0031005)
0.1 3.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 4.8 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.1 2.0 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 3.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 2.1 GO:0002162 dystroglycan binding(GO:0002162)
0.1 14.2 GO:0017124 SH3 domain binding(GO:0017124)
0.1 6.3 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 3.0 GO:0005109 frizzled binding(GO:0005109)
0.1 3.6 GO:0001012 RNA polymerase II regulatory region DNA binding(GO:0001012)
0.1 8.2 GO:0015075 ion transmembrane transporter activity(GO:0015075)
0.1 6.0 GO:0043130 ubiquitin binding(GO:0043130)
0.1 4.9 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 0.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 6.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 4.9 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.1 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 2.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 15.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 0.6 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 3.3 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 0.9 GO:0005537 mannose binding(GO:0005537)
0.0 1.4 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 2.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 2.7 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 6.2 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 3.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 3.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 0.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 2.2 GO:0003684 damaged DNA binding(GO:0003684)
0.0 3.0 GO:0005178 integrin binding(GO:0005178)
0.0 1.0 GO:0017022 myosin binding(GO:0017022)
0.0 3.7 GO:0008017 microtubule binding(GO:0008017)
0.0 1.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 4.1 GO:0003924 GTPase activity(GO:0003924)
0.0 1.3 GO:0051087 chaperone binding(GO:0051087)
0.0 0.8 GO:0005518 collagen binding(GO:0005518)
0.0 5.6 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 21.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
1.1 33.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.8 76.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.6 7.8 ST JAK STAT PATHWAY Jak-STAT Pathway
0.6 43.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.6 22.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.6 1.7 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.6 6.9 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.5 6.1 PID IL5 PATHWAY IL5-mediated signaling events
0.5 21.7 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.5 4.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.4 21.8 ST GA13 PATHWAY G alpha 13 Pathway
0.4 12.9 PID ALK1 PATHWAY ALK1 signaling events
0.4 7.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.4 12.5 PID AURORA A PATHWAY Aurora A signaling
0.3 8.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.3 6.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3 9.4 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.3 17.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.3 6.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.2 7.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.2 10.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.2 12.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2 5.8 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.2 5.1 PID CONE PATHWAY Visual signal transduction: Cones
0.2 2.2 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.2 7.2 PID MYC PATHWAY C-MYC pathway
0.2 5.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 4.4 ST G ALPHA I PATHWAY G alpha i Pathway
0.2 0.8 PID S1P S1P2 PATHWAY S1P2 pathway
0.2 3.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 8.4 PID ENDOTHELIN PATHWAY Endothelins
0.1 6.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 5.8 PID ARF6 PATHWAY Arf6 signaling events
0.1 3.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 3.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 5.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 2.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 5.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 29.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 10.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 2.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 38.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 5.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.7 PID LKB1 PATHWAY LKB1 signaling events
0.1 3.2 PID PLK1 PATHWAY PLK1 signaling events
0.1 1.3 PID BMP PATHWAY BMP receptor signaling
0.0 1.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 2.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 4.4 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 2.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 72.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
1.4 28.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
1.2 25.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.8 2.4 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.7 7.9 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.6 17.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.6 14.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.6 8.0 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.6 5.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.5 10.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.5 11.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.5 27.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.5 15.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.4 6.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.4 4.6 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.4 4.6 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.4 6.6 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.4 6.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.3 9.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.3 4.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.3 6.2 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.3 9.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.3 3.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.3 18.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.3 5.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.3 6.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.3 14.4 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.3 8.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.3 7.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 5.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.2 37.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.2 4.2 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.2 3.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 5.0 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.2 8.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 3.7 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.2 7.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.2 5.3 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.2 8.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.2 7.4 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.2 8.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 5.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.2 5.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.2 3.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.2 4.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 5.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 4.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 10.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 4.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 4.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 4.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 1.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 3.5 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 6.4 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 2.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 17.6 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.1 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 2.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 6.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 2.1 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 3.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.9 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 2.8 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 4.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.8 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling