GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)


Results for KLF8

Z-value: 1.95

Motif logo

Transcription factors associated with KLF8

Gene Symbol Gene ID Gene Info
ENSG00000102349.10 Kruppel like factor 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot

Activity profile of KLF8 motif

Sorted Z-values of KLF8 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_222846 53.06 ENST00000251595.6
hemoglobin, alpha 2
chr6_+_31865552 38.14 ENST00000469372.1
complement component 2
chr21_-_46330545 36.81 ENST00000320216.6
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr19_-_17185848 34.86 ENST00000593360.1
HAUS augmin-like complex, subunit 8
chr1_+_6845384 34.09 ENST00000303635.7
calmodulin binding transcription activator 1
chr16_+_226658 30.94 ENST00000320868.5
hemoglobin, alpha 1
chr3_+_10206545 27.40 ENST00000256458.4
interleukin-1 receptor-associated kinase 2
chr6_-_33048483 27.18 ENST00000419277.1
major histocompatibility complex, class II, DP alpha 1
chr15_+_69222827 27.07 ENST00000310673.3
sperm equatorial segment protein 1
NADPH oxidase, EF-hand calcium binding domain 5
chr17_-_42277203 26.83 ENST00000587097.1
ataxin 7-like 3
chr1_-_38157877 26.55 ENST00000477060.1
chromosome 1 open reading frame 109
chr3_+_40566369 26.53 ENST00000403205.2
zinc finger protein 621
chr12_+_50355647 26.23 ENST00000293599.6
aquaporin 5
chr14_-_106209368 24.37 ENST00000390548.2
immunoglobulin heavy constant gamma 1 (G1m marker)
chr22_+_22712087 24.03 ENST00000390294.2
immunoglobulin lambda variable 1-47
chr8_-_27468842 23.48 ENST00000523500.1
chr15_+_69222909 22.48 ENST00000455873.3
NADPH oxidase, EF-hand calcium binding domain 5
chr3_-_58572760 22.42 ENST00000447756.2
family with sequence similarity 107, member A
chr11_-_64512469 22.05 ENST00000377485.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr19_+_16435625 21.76 ENST00000248071.5
Kruppel-like factor 2
chr3_-_126194707 21.68 ENST00000336332.5
ZXD family zinc finger C
chr1_-_182360498 21.03 ENST00000417584.2
glutamate-ammonia ligase
chr9_+_139871948 20.97 ENST00000224167.2
prostaglandin D2 synthase 21kDa (brain)
chr9_+_139874683 20.84 ENST00000444903.1
prostaglandin D2 synthase 21kDa (brain)
chr20_+_30640004 20.79 ENST00000520553.1
hemopoietic cell kinase
chr17_-_41465674 20.55 ENST00000592135.1
long intergenic non-protein coding RNA 910
chr8_-_27468945 20.37 ENST00000405140.3
chr18_-_74701962 20.18 ENST00000585201.1
myelin basic protein
chr5_-_139944196 19.85 ENST00000357560.4
amyloid beta (A4) precursor protein-binding, family B, member 3
chr19_+_56915668 19.61 ENST00000333201.9
zinc finger protein 583
chr19_+_35630022 19.28 ENST00000589209.1
FXYD domain containing ion transport regulator 1
chr11_-_64512273 19.27 ENST00000377497.3
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr20_+_30639991 19.17 ENST00000534862.1
hemopoietic cell kinase
chr19_+_2977444 19.09 ENST00000246112.4
transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
chr6_+_33048222 19.07 ENST00000428835.1
major histocompatibility complex, class II, DP beta 1
chr22_+_45898712 18.81 ENST00000455233.1
fibulin 1
chr18_-_74728998 18.81 ENST00000359645.3
myelin basic protein
chr19_+_35629702 18.77 ENST00000351325.4
FXYD domain containing ion transport regulator 1
chr22_+_22681656 18.61 ENST00000390291.2
immunoglobulin lambda variable 1-50 (non-functional)
chr2_+_95691445 18.41 ENST00000353004.3
mal, T-cell differentiation protein
chr22_+_23248512 18.40 ENST00000390325.2
immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr19_+_45409011 18.37 ENST00000252486.4
apolipoprotein E
chr17_+_1665345 18.36 ENST00000576406.1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr8_-_27457494 18.26 ENST00000521770.1
chr6_-_170101749 18.25 ENST00000448612.1
WD repeat domain 27
chr14_-_106092403 18.13 ENST00000390543.2
immunoglobulin heavy constant gamma 4 (G4m marker)
chr19_+_57831829 18.09 ENST00000321545.4
zinc finger protein 543
chr11_-_117747607 17.90 ENST00000540359.1
FXYD domain containing ion transport regulator 6
chr6_-_32557610 17.90 ENST00000360004.5
major histocompatibility complex, class II, DR beta 1
chr2_+_95691417 17.86 ENST00000309988.4
mal, T-cell differentiation protein
chr19_+_5623186 17.82 ENST00000538656.1
scaffold attachment factor B
chr17_+_38083977 17.61 ENST00000578802.1
chr1_+_1510337 16.84 ENST00000366221.2
Uncharacterized protein
chr6_+_42847348 16.64 ENST00000493763.1
ribosomal protein L7-like 1
chr20_-_4804244 16.46 ENST00000379400.3
Ras association (RalGDS/AF-6) domain family member 2
chr9_+_139873264 16.43 ENST00000446677.1
prostaglandin D2 synthase 21kDa (brain)
chr2_+_90139056 16.28 ENST00000492446.1
immunoglobulin kappa variable 1D-16
chr14_+_102027688 16.27 ENST00000510508.4
deiodinase, iodothyronine, type III
chr10_-_105452917 16.20 ENST00000427662.2
SH3 and PX domains 2A
chr2_-_89310012 16.20 ENST00000493819.1
immunoglobulin kappa variable 1-9
chr1_-_11866034 15.70 ENST00000376590.3
methylenetetrahydrofolate reductase (NAD(P)H)
chr19_+_53836985 15.43 ENST00000601857.1
zinc finger protein 845
chr3_-_57678772 15.42 ENST00000311128.5
DENN/MADD domain containing 6A
chr12_+_4918342 15.38 ENST00000280684.3
potassium voltage-gated channel, shaker-related subfamily, member 6
chr19_-_33793430 15.36 ENST00000498907.2
CCAAT/enhancer binding protein (C/EBP), alpha
chr1_-_182361327 15.30 ENST00000331872.6
glutamate-ammonia ligase
chr22_+_22786288 15.15 ENST00000390301.2
immunoglobulin lambda variable 1-36
chr16_+_84178874 15.05 ENST00000378553.5
dynein, axonemal, assembly factor 1
chr1_-_31230650 15.00 ENST00000294507.3
lysosomal protein transmembrane 5
chr8_+_24772455 14.81 ENST00000433454.2
neurofilament, medium polypeptide
chr19_+_7069426 14.70 ENST00000252840.6
zinc finger protein 557
chr14_-_81687197 14.55 ENST00000553612.1
general transcription factor IIA, 1, 19/37kDa
chr11_-_117748138 14.46 ENST00000527717.1
FXYD domain containing ion transport regulator 6
chr1_+_151254738 14.30 ENST00000336715.6
zinc finger protein 687
chr22_+_22735135 14.24 ENST00000390297.2
immunoglobulin lambda variable 1-44
chr19_-_11591848 14.16 ENST00000359227.3
ELAV like neuron-specific RNA binding protein 3
chr14_+_57857262 14.15 ENST00000555166.1
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr7_-_35734730 14.14 ENST00000396081.1
HERPUD family member 2
chr15_+_90777424 14.12 ENST00000561433.1
GDP-D-glucose phosphorylase 1
chr14_+_73704201 14.05 ENST00000340738.5
papilin, proteoglycan-like sulfated glycoprotein
chr1_+_26644441 14.02 ENST00000374213.2
CD52 molecule
chr11_+_117049445 14.00 ENST00000324225.4
SID1 transmembrane family, member 2
chr19_-_49945617 13.85 ENST00000600601.1
solute carrier family 17 (vesicular glutamate transporter), member 7
chr3_-_167813672 13.85 ENST00000470487.1
golgi integral membrane protein 4
chr21_-_46348694 13.83 ENST00000355153.4
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr21_+_47878757 13.81 ENST00000400274.1
DIP2 disco-interacting protein 2 homolog A (Drosophila)
chr19_+_50706866 13.81 ENST00000440075.2
myosin, heavy chain 14, non-muscle
chr11_+_62439126 13.80 ENST00000377953.3
chromosome 11 open reading frame 83
chr17_-_5138099 13.73 ENST00000571800.1
SLP adaptor and CSK interacting membrane protein
chr22_-_19974616 13.59 ENST00000344269.3
armadillo repeat gene deleted in velocardiofacial syndrome
chr1_+_1260147 13.58 ENST00000343938.4
glycolipid transfer protein domain containing 1
chr14_-_106054659 13.51 ENST00000390539.2
immunoglobulin heavy constant alpha 2 (A2m marker)
chr9_-_86571628 13.48 ENST00000376344.3
chromosome 9 open reading frame 64
chr20_+_1206679 13.46 ENST00000402452.1
RAD21-like 1 (S. pombe)
chr11_-_125366089 13.45 ENST00000366139.3
fasciculation and elongation protein zeta 1 (zygin I)
chr16_+_58283814 13.39 ENST00000443128.2
coiled-coil domain containing 113
chr22_+_39745930 13.32 ENST00000318801.4
synaptogyrin 1
chr17_+_1665253 13.26 ENST00000254722.4
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr16_-_1843720 13.23 ENST00000415638.3
insulin-like growth factor binding protein, acid labile subunit
chr13_-_44453826 13.19 ENST00000444614.3
coiled-coil domain containing 122
chrX_+_16737718 13.19 ENST00000380155.3
synapse associated protein 1
chr6_-_84419101 13.18 ENST00000520302.1
synaptosomal-associated protein, 91kDa
chr11_-_64511789 13.12 ENST00000419843.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr8_+_95908041 13.11 ENST00000396113.1
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr11_-_72385437 13.09 ENST00000418754.2
phosphodiesterase 2A, cGMP-stimulated
chr6_-_152957944 13.07 ENST00000423061.1
spectrin repeat containing, nuclear envelope 1
chrX_-_17878827 13.05 ENST00000360011.1
retinoic acid induced 2
chr20_-_35492048 13.04 ENST00000237536.4
suppressor of glucose, autophagy associated 1
chr11_+_1891380 12.99 ENST00000429923.1
lymphocyte-specific protein 1
chr3_+_153839149 12.96 ENST00000465093.1
Rho guanine nucleotide exchange factor (GEF) 26
chr22_+_47158518 12.86 ENST00000337137.4
TBC1 domain family, member 22A
chr3_-_58613323 12.86 ENST00000474531.1
family with sequence similarity 107, member A
chr4_+_4388805 12.86 ENST00000504171.1
Homo sapiens neuron specific gene family member 1 (NSG1), transcript variant 3, mRNA.
chr14_-_106330072 12.81 ENST00000488476.1
immunoglobulin heavy joining 5
chrX_+_153524024 12.81 ENST00000369915.3
transketolase-like 1
chr19_-_54726850 12.78 ENST00000245620.9
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
chr14_-_81687575 12.77 ENST00000434192.2
general transcription factor IIA, 1, 19/37kDa
chr11_-_61129335 12.72 ENST00000545361.1
cytochrome b561 family, member A3
chr11_-_113746212 12.70 ENST00000537642.1
ubiquitin specific peptidase 28
chr3_+_45071622 12.62 ENST00000428034.1
C-type lectin domain family 3, member B
chr1_+_156698234 12.61 ENST00000368218.4
ribosomal RNA adenine dimethylase domain containing 1
chr22_-_39548627 12.57 ENST00000216133.5
chromobox homolog 7
chr5_+_150400124 12.53 ENST00000388825.4
glutathione peroxidase 3 (plasma)
chr19_+_5681011 12.48 ENST00000581893.1
hydroxysteroid (11-beta) dehydrogenase 1-like
chrX_-_2418596 12.48 ENST00000381218.3
zinc finger, BED-type containing 1
chr14_-_100070363 12.40 ENST00000380243.4
coiled-coil domain containing 85C
chr22_+_23040274 12.39 ENST00000390306.2
immunoglobulin lambda variable 2-23
chr17_-_76778339 12.35 ENST00000591455.1
cytohesin 1
chr7_-_139876812 12.33 ENST00000397560.2
lysine (K)-specific demethylase 7A
chr14_-_106174960 12.31 ENST00000390547.2
immunoglobulin heavy constant alpha 1
chr1_+_233086326 12.30 ENST00000366628.5
nucleoside-triphosphatase, cancer-related
chr22_+_23237555 12.29 ENST00000390321.2
immunoglobulin lambda constant 1 (Mcg marker)
chr14_-_21493884 12.28 ENST00000556974.1
NDRG family member 2
chr19_+_7069690 12.27 ENST00000439035.2
zinc finger protein 557
chr16_+_4784458 12.21 ENST00000590191.1
chromosome 16 open reading frame 71
chr1_-_11865982 12.20 ENST00000418034.1
methylenetetrahydrofolate reductase (NAD(P)H)
chr11_-_117747434 12.13 ENST00000529335.2
FXYD domain containing ion transport regulator 6
chr17_-_617949 12.10 ENST00000401468.3
vacuolar protein sorting 53 homolog (S. cerevisiae)
chr16_+_1291240 12.04 ENST00000561736.1
tryptase alpha/beta 1
chr17_-_42992856 12.04 ENST00000588316.1
glial fibrillary acidic protein
chr19_-_54784353 11.94 ENST00000391746.1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
chr5_-_176057365 11.92 ENST00000310112.3
synuclein, beta
chr16_+_4784273 11.89 ENST00000299320.5
chromosome 16 open reading frame 71
chr12_+_66218212 11.88 ENST00000393578.3
high mobility group AT-hook 2
chr19_+_57742431 11.87 ENST00000302804.7
aurora kinase C
chr14_+_74111578 11.84 ENST00000554113.1
dynein, axonemal, light chain 1
chr9_+_124048864 11.75 ENST00000545652.1
chr19_+_39897453 11.68 ENST00000597629.1
ZFP36 ring finger protein
chr1_-_15850839 11.67 ENST00000348549.5
caspase 9, apoptosis-related cysteine peptidase
chr10_+_88728189 11.63 ENST00000416348.1
adipogenesis regulatory factor
chr2_+_10184302 11.61 ENST00000440320.1
Kruppel-like factor 11
chr2_+_68961905 11.61 ENST00000295381.3
Rho GTPase activating protein 25
chr2_-_99224915 11.60 ENST00000328709.3
cytochrome c oxidase assembly factor 5
chr2_-_71454185 11.58 ENST00000244221.8
poly(A) binding protein interacting protein 2B
chr19_-_47164386 11.56 ENST00000391916.2
dishevelled-binding antagonist of beta-catenin 3
chr14_-_60337684 11.55 ENST00000267484.5
reticulon 1
chr22_-_18923655 11.54 ENST00000438924.1
proline dehydrogenase (oxidase) 1
chr19_-_18391708 11.53 ENST00000600972.1
jun D proto-oncogene
chr2_+_25016282 11.52 ENST00000260662.1
centromere protein O
chr10_+_134145614 11.49 ENST00000368615.3
leucine rich repeat containing 27
chr3_-_167813132 11.49 ENST00000309027.4
golgi integral membrane protein 4
chr19_+_1067271 11.47 ENST00000536472.1
histocompatibility (minor) HA-1
chr19_-_14016877 11.47 ENST00000454313.1
chromosome 19 open reading frame 57
chr1_-_160681593 11.43 ENST00000368045.3
CD48 molecule
chr10_-_21786179 11.41 ENST00000377113.5
cancer susceptibility candidate 10
chr14_-_21567009 11.39 ENST00000556174.1
zinc finger protein 219
chr9_-_111929560 11.39 ENST00000561981.2
ferric-chelate reductase 1-like
chr1_-_213031418 11.39 ENST00000356684.3
FLVCR1 antisense RNA 1 (head to head)
chrX_-_47479246 11.31 ENST00000295987.7
synapsin I
chr22_+_23243156 11.28 ENST00000390323.2
immunoglobulin lambda constant 2 (Kern-Oz- marker)
chr7_+_30960915 11.28 ENST00000441328.2
aquaporin 1 (Colton blood group)
chr8_+_141521386 11.27 ENST00000220913.5
chromatin accessibility complex 1
chrX_-_17879356 11.26 ENST00000331511.1
retinoic acid induced 2
chr1_+_22963158 11.25 ENST00000438241.1
complement component 1, q subcomponent, A chain
chr1_+_202830876 11.24 ENST00000456105.2
chr19_-_37019562 11.22 ENST00000523638.1
zinc finger protein 260
chr20_+_58508817 11.12 ENST00000358293.3
family with sequence similarity 217, member B
chrX_+_56259316 11.08 ENST00000468660.1
Kruppel-like factor 8
chr9_-_93405352 11.05 ENST00000375765.3
DIRAS family, GTP-binding RAS-like 2
chr11_-_113746277 11.05 ENST00000003302.4
ubiquitin specific peptidase 28
chrX_-_153881842 11.04 ENST00000369585.3
cancer/testis antigen 2
chr13_-_114898016 11.03 ENST00000542651.1
RAS p21 protein activator 3
chr4_+_7045042 11.01 ENST00000310074.7
transcriptional adaptor 2B
chr1_-_156217822 11.01 ENST00000368270.1
progestin and adipoQ receptor family member VI
chr4_-_166034029 11.00 ENST00000306480.6
transmembrane protein 192
chr5_+_141303373 10.97 ENST00000432126.2
chr1_-_17445930 10.96 ENST00000375486.4
peptidyl arginine deiminase, type II
chr11_-_64510409 10.94 ENST00000394429.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr11_+_82612740 10.93 ENST00000524921.1
chromosome 11 open reading frame 82
chr16_+_23847339 10.85 ENST00000303531.7
protein kinase C, beta
chr9_+_87283430 10.85 ENST00000376214.1
neurotrophic tyrosine kinase, receptor, type 2
chr11_-_64512803 10.85 ENST00000377489.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr16_-_30032610 10.82 ENST00000574405.1
double C2-like domains, alpha
chr11_+_119076745 10.82 ENST00000264033.4
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr15_+_31619013 10.77 ENST00000307145.3
Kruppel-like factor 13
chr5_-_130970723 10.77 ENST00000308008.6
Rap guanine nucleotide exchange factor (GEF) 6
chr6_-_46459099 10.75 ENST00000371374.1
regulator of calcineurin 2
chr20_-_58508702 10.73 ENST00000357552.3
synaptonemal complex protein 2
chr17_-_42402138 10.71 ENST00000592857.1
solute carrier family 25, member 39
chr20_+_3801162 10.66 ENST00000379573.2
adaptor-related protein complex 5, sigma 1 subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
16.5 49.6 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
14.1 42.2 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
13.7 13.7 GO:0070374 positive regulation of ERK1 and ERK2 cascade(GO:0070374)
13.3 79.8 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
9.2 45.8 GO:0015670 carbon dioxide transport(GO:0015670)
9.1 36.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
8.5 25.5 GO:0033693 neurofilament bundle assembly(GO:0033693)
7.8 39.0 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
7.3 21.8 GO:0071409 cellular response to cycloheximide(GO:0071409)
7.1 7.1 GO:0060008 Sertoli cell differentiation(GO:0060008)
7.0 21.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
6.9 41.7 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
6.8 20.4 GO:1905154 negative regulation of membrane invagination(GO:1905154)
6.7 13.5 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
6.5 6.5 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
6.5 64.6 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
6.4 25.7 GO:0042412 taurine biosynthetic process(GO:0042412)
6.4 6.4 GO:0051604 protein maturation(GO:0051604)
6.3 31.6 GO:0071279 cellular response to cobalt ion(GO:0071279)
6.1 18.4 GO:1902994 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
6.0 24.0 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
5.9 17.6 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
5.8 29.0 GO:0002399 MHC class II protein complex assembly(GO:0002399)
5.8 17.4 GO:1990502 dense core granule maturation(GO:1990502)
5.6 27.9 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
5.4 21.7 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
4.6 18.6 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
4.6 13.8 GO:0042137 sequestering of neurotransmitter(GO:0042137)
4.6 27.4 GO:0005985 sucrose metabolic process(GO:0005985)
4.5 18.2 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
4.5 4.5 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
4.4 4.4 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416)
4.4 13.1 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
4.2 8.4 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
4.2 12.5 GO:0006982 response to lipid hydroperoxide(GO:0006982)
4.1 4.1 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
4.1 12.3 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
4.1 4.1 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
4.0 12.0 GO:1900073 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
4.0 7.9 GO:0050902 leukocyte adhesive activation(GO:0050902)
3.9 23.4 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
3.8 15.3 GO:0018094 protein polyglycylation(GO:0018094)
3.8 38.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
3.7 11.2 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
3.7 22.0 GO:0010133 proline catabolic process to glutamate(GO:0010133)
3.7 11.0 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
3.6 14.5 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
3.6 14.5 GO:2000410 regulation of thymocyte migration(GO:2000410)
3.6 14.4 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
3.6 21.5 GO:0034587 piRNA metabolic process(GO:0034587)
3.6 21.3 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
3.5 7.1 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
3.5 62.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
3.5 3.5 GO:0070560 protein secretion by platelet(GO:0070560)
3.4 10.3 GO:1900104 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
3.4 6.8 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
3.4 10.3 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
3.4 10.1 GO:0071529 cementum mineralization(GO:0071529)
3.3 13.3 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
3.3 20.0 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
3.3 13.3 GO:0044458 motile cilium assembly(GO:0044458)
3.3 13.3 GO:0014807 regulation of somitogenesis(GO:0014807)
3.3 3.3 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
3.3 16.5 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
3.3 16.4 GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
3.3 58.9 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
3.3 9.8 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
3.3 9.8 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
3.2 6.5 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
3.2 13.0 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
3.2 9.7 GO:0035610 protein side chain deglutamylation(GO:0035610)
3.2 9.6 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
3.1 25.1 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
3.1 6.3 GO:1903413 cellular response to bile acid(GO:1903413)
3.1 9.4 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
3.1 9.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
3.1 21.5 GO:0045007 depurination(GO:0045007)
3.1 18.4 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
3.0 12.2 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
3.0 15.1 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
3.0 3.0 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
3.0 3.0 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
2.9 8.8 GO:0007497 posterior midgut development(GO:0007497)
2.9 26.4 GO:0060267 positive regulation of respiratory burst(GO:0060267)
2.9 5.8 GO:1901859 negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
2.9 8.6 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
2.9 8.6 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
2.9 17.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
2.8 5.7 GO:0033590 response to cobalamin(GO:0033590)
2.8 28.2 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
2.8 8.5 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
2.8 8.4 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
2.8 2.8 GO:2000584 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
2.8 2.8 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
2.8 5.5 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
2.8 16.5 GO:0051414 response to cortisol(GO:0051414)
2.8 11.0 GO:1904448 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
2.7 30.2 GO:0033227 dsRNA transport(GO:0033227)
2.7 11.0 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
2.7 8.2 GO:1902534 single-organism membrane invagination(GO:1902534)
2.7 5.5 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
2.7 8.2 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
2.7 2.7 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
2.7 8.1 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
2.7 18.9 GO:2001023 regulation of response to drug(GO:2001023)
2.7 10.8 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
2.7 5.4 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
2.7 8.0 GO:0021571 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
2.7 2.7 GO:0043379 memory T cell differentiation(GO:0043379)
2.7 2.7 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
2.6 15.5 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
2.6 2.6 GO:0051105 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
2.6 5.1 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
2.6 28.2 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
2.6 5.1 GO:1990164 histone H2A phosphorylation(GO:1990164)
2.6 10.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
2.6 2.6 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
2.5 12.7 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
2.5 2.5 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
2.5 12.6 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
2.5 15.1 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
2.5 5.0 GO:0009648 photoperiodism(GO:0009648) entrainment of circadian clock(GO:0009649) entrainment of circadian clock by photoperiod(GO:0043153)
2.5 5.0 GO:0072384 organelle transport along microtubule(GO:0072384)
2.5 19.7 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
2.5 7.4 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
2.4 26.9 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
2.4 9.7 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
2.4 14.4 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
2.4 7.1 GO:0061760 antifungal innate immune response(GO:0061760)
2.4 7.1 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
2.4 9.5 GO:0070830 bicellular tight junction assembly(GO:0070830)
2.4 28.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
2.4 9.4 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
2.3 23.4 GO:0048102 autophagic cell death(GO:0048102)
2.3 157.0 GO:0006910 phagocytosis, recognition(GO:0006910)
2.3 4.7 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
2.3 16.3 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
2.3 16.3 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
2.3 7.0 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
2.3 16.2 GO:0060294 cilium movement involved in cell motility(GO:0060294)
2.3 9.2 GO:1990262 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
2.3 6.9 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
2.3 11.4 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
2.3 13.7 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
2.3 4.5 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
2.3 6.8 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
2.3 4.5 GO:0061110 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
2.2 9.0 GO:0001826 inner cell mass cell differentiation(GO:0001826)
2.2 4.5 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
2.2 13.5 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
2.2 33.5 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
2.2 2.2 GO:0051885 positive regulation of anagen(GO:0051885)
2.2 4.4 GO:0060374 mast cell differentiation(GO:0060374)
2.2 2.2 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
2.2 15.4 GO:0006772 thiamine metabolic process(GO:0006772)
2.2 32.5 GO:0015671 oxygen transport(GO:0015671)
2.2 6.5 GO:0000160 phosphorelay signal transduction system(GO:0000160)
2.2 10.8 GO:0035063 nuclear speck organization(GO:0035063)
2.2 10.8 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
2.1 6.4 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
2.1 6.4 GO:0001207 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
2.1 6.4 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
2.1 16.9 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
2.1 14.7 GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter(GO:0072364)
2.1 8.4 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
2.1 12.5 GO:2000501 regulation of natural killer cell chemotaxis(GO:2000501) positive regulation of natural killer cell chemotaxis(GO:2000503)
2.1 6.2 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
2.1 8.3 GO:2000416 regulation of eosinophil migration(GO:2000416) positive regulation of eosinophil migration(GO:2000418)
2.1 8.3 GO:1902075 cellular response to salt(GO:1902075)
2.1 14.4 GO:0032025 response to cobalt ion(GO:0032025)
2.1 6.2 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
2.1 4.1 GO:1904048 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814) regulation of spontaneous neurotransmitter secretion(GO:1904048)
2.0 2.0 GO:0030259 lipid glycosylation(GO:0030259)
2.0 6.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
2.0 10.1 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
2.0 10.0 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
2.0 9.9 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
2.0 9.9 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
2.0 21.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
2.0 9.9 GO:0018022 peptidyl-lysine methylation(GO:0018022)
2.0 5.9 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
2.0 7.8 GO:1905073 proepicardium development(GO:0003342) septum transversum development(GO:0003343) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
2.0 3.9 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
1.9 5.8 GO:0090034 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
1.9 9.7 GO:1901907 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
1.9 7.7 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
1.9 5.8 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
1.9 3.9 GO:0042116 macrophage activation(GO:0042116)
1.9 3.8 GO:0006021 inositol biosynthetic process(GO:0006021)
1.9 5.7 GO:0008355 olfactory learning(GO:0008355)
1.9 5.7 GO:1904317 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
1.9 5.6 GO:0070781 response to biotin(GO:0070781)
1.9 9.4 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
1.9 15.0 GO:0015705 iodide transport(GO:0015705)
1.9 13.1 GO:0071877 regulation of adrenergic receptor signaling pathway(GO:0071877)
1.9 5.6 GO:0007602 phototransduction(GO:0007602)
1.8 3.7 GO:0060086 circadian temperature homeostasis(GO:0060086)
1.8 22.1 GO:0006884 cell volume homeostasis(GO:0006884)
1.8 5.5 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
1.8 5.5 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
1.8 16.2 GO:0036158 outer dynein arm assembly(GO:0036158)
1.8 7.2 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
1.8 10.8 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
1.8 9.0 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
1.8 157.9 GO:0006958 complement activation, classical pathway(GO:0006958)
1.8 9.0 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
1.8 10.7 GO:0046208 spermine catabolic process(GO:0046208)
1.8 10.7 GO:0032100 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
1.8 5.3 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
1.8 1.8 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547) regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
1.8 1.8 GO:0071421 manganese ion transmembrane transport(GO:0071421)
1.8 5.3 GO:1901727 positive regulation of deacetylase activity(GO:0090045) positive regulation of histone deacetylase activity(GO:1901727)
1.8 3.5 GO:0070055 mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) mRNA endonucleolytic cleavage involved in unfolded protein response(GO:0070055)
1.8 21.2 GO:0045794 negative regulation of cell volume(GO:0045794)
1.8 22.8 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
1.7 5.2 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
1.7 10.5 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
1.7 7.0 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
1.7 1.7 GO:0060484 lung-associated mesenchyme development(GO:0060484)
1.7 6.9 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
1.7 5.2 GO:0003095 pressure natriuresis(GO:0003095)
1.7 3.5 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
1.7 10.3 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
1.7 12.0 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
1.7 5.1 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
1.7 1.7 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
1.7 6.8 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
1.7 13.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
1.7 5.1 GO:1902809 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
1.7 5.1 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
1.7 6.8 GO:0003219 cardiac right ventricle formation(GO:0003219)
1.7 10.1 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
1.7 3.4 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
1.7 20.2 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
1.7 1.7 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
1.7 5.0 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
1.7 3.3 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
1.7 5.0 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
1.6 1.6 GO:0007521 muscle cell fate determination(GO:0007521)
1.6 13.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
1.6 8.2 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
1.6 4.9 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
1.6 16.4 GO:0006069 ethanol oxidation(GO:0006069)
1.6 6.6 GO:0010165 response to X-ray(GO:0010165)
1.6 3.3 GO:0032607 interferon-alpha production(GO:0032607)
1.6 4.9 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
1.6 6.5 GO:0071321 cellular response to cGMP(GO:0071321)
1.6 11.4 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
1.6 11.4 GO:0086036 regulation of cardiac muscle cell membrane potential(GO:0086036)
1.6 8.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
1.6 6.5 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
1.6 4.8 GO:0061461 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
1.6 3.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
1.6 3.2 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
1.6 6.3 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664)
1.6 6.3 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
1.6 3.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
1.6 11.0 GO:0043249 erythrocyte maturation(GO:0043249)
1.6 1.6 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
1.6 18.7 GO:2001135 regulation of endocytic recycling(GO:2001135)
1.6 6.2 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
1.5 10.8 GO:1903689 regulation of wound healing, spreading of epidermal cells(GO:1903689) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
1.5 60.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
1.5 7.7 GO:0043117 positive regulation of vascular permeability(GO:0043117)
1.5 1.5 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
1.5 16.9 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
1.5 9.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
1.5 6.1 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
1.5 4.5 GO:0042360 vitamin E metabolic process(GO:0042360)
1.5 18.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
1.5 3.0 GO:0044782 cilium organization(GO:0044782)
1.5 4.5 GO:0032571 response to vitamin K(GO:0032571)
1.5 6.0 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
1.5 6.0 GO:0008286 insulin receptor signaling pathway(GO:0008286)
1.5 3.0 GO:2000382 positive regulation of mesoderm development(GO:2000382)
1.5 16.5 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
1.5 22.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
1.5 7.4 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
1.5 5.9 GO:0009409 response to cold(GO:0009409)
1.5 8.8 GO:1903715 regulation of aerobic respiration(GO:1903715)
1.5 5.9 GO:1903438 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
1.5 8.8 GO:0017121 phospholipid scrambling(GO:0017121)
1.5 8.8 GO:0001955 blood vessel maturation(GO:0001955)
1.5 2.9 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
1.5 7.3 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
1.5 11.7 GO:0007258 JUN phosphorylation(GO:0007258)
1.5 8.7 GO:0090043 tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043)
1.5 36.4 GO:0001921 positive regulation of receptor recycling(GO:0001921)
1.5 2.9 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
1.4 5.8 GO:0044026 DNA hypermethylation(GO:0044026)
1.4 4.3 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
1.4 4.3 GO:1900369 transcription, RNA-templated(GO:0001172) regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369) positive regulation of protein localization to nucleolus(GO:1904751)
1.4 7.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
1.4 12.9 GO:0016191 synaptic vesicle uncoating(GO:0016191)
1.4 4.3 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
1.4 11.4 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
1.4 2.8 GO:0009299 mRNA transcription(GO:0009299)
1.4 2.8 GO:0033602 negative regulation of dopamine secretion(GO:0033602)
1.4 4.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
1.4 4.2 GO:1904430 negative regulation of t-circle formation(GO:1904430)
1.4 23.7 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
1.4 4.2 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
1.4 7.0 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
1.4 2.8 GO:0070256 negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
1.4 12.4 GO:0032341 aldosterone metabolic process(GO:0032341) aldosterone biosynthetic process(GO:0032342)
1.4 5.5 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
1.4 4.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
1.4 5.5 GO:0061535 glutamate secretion, neurotransmission(GO:0061535)
1.4 1.4 GO:1903038 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
1.4 4.1 GO:0032007 negative regulation of TOR signaling(GO:0032007)
1.4 4.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
1.4 8.2 GO:0018343 protein farnesylation(GO:0018343)
1.4 4.1 GO:0032526 response to retinoic acid(GO:0032526)
1.4 12.3 GO:0042373 vitamin K metabolic process(GO:0042373)
1.4 13.5 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
1.4 4.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
1.3 5.4 GO:1905232 cellular response to L-glutamate(GO:1905232)
1.3 21.5 GO:0007130 synaptonemal complex assembly(GO:0007130)
1.3 5.4 GO:0032252 secretory granule localization(GO:0032252)
1.3 2.7 GO:0015917 aminophospholipid transport(GO:0015917)
1.3 6.7 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
1.3 16.0 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
1.3 8.0 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
1.3 8.0 GO:0070255 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
1.3 5.3 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
1.3 13.3 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
1.3 4.0 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
1.3 9.3 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
1.3 4.0 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
1.3 3.9 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
1.3 3.9 GO:0006566 threonine metabolic process(GO:0006566)
1.3 3.9 GO:0060974 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
1.3 95.3 GO:0071277 cellular response to calcium ion(GO:0071277)
1.3 5.2 GO:0043171 peptide catabolic process(GO:0043171)
1.3 5.2 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
1.3 3.9 GO:1902490 regulation of sperm capacitation(GO:1902490)
1.3 10.4 GO:0014848 urinary bladder smooth muscle contraction(GO:0014832) urinary tract smooth muscle contraction(GO:0014848)
1.3 6.5 GO:0003431 growth plate cartilage chondrocyte growth(GO:0003430) growth plate cartilage chondrocyte development(GO:0003431)
1.3 5.1 GO:0034699 response to luteinizing hormone(GO:0034699) cellular response to luteinizing hormone stimulus(GO:0071373)
1.3 2.6 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
1.3 5.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
1.3 5.1 GO:0019054 modulation by virus of host morphology or physiology(GO:0019048) modulation by virus of host process(GO:0019054)
1.3 14.0 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
1.3 3.8 GO:0010046 response to mycotoxin(GO:0010046)
1.3 26.3 GO:0032011 ARF protein signal transduction(GO:0032011)
1.2 6.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
1.2 5.0 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
1.2 17.4 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
1.2 11.1 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
1.2 8.6 GO:0015824 proline transport(GO:0015824)
1.2 9.8 GO:0002315 marginal zone B cell differentiation(GO:0002315)
1.2 14.6 GO:0051865 protein autoubiquitination(GO:0051865)
1.2 3.6 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
1.2 2.4 GO:0046015 regulation of transcription by glucose(GO:0046015)
1.2 8.5 GO:0002175 protein localization to paranode region of axon(GO:0002175)
1.2 6.0 GO:0006543 glutamine catabolic process(GO:0006543)
1.2 9.7 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
1.2 2.4 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
1.2 1.2 GO:0071848 regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
1.2 4.8 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
1.2 7.1 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
1.2 1.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
1.2 7.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
1.2 4.8 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
1.2 1.2 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
1.2 7.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
1.2 4.7 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
1.2 16.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
1.2 30.6 GO:0001825 blastocyst formation(GO:0001825)
1.2 4.7 GO:0010561 negative regulation of glycoprotein biosynthetic process(GO:0010561)
1.2 8.2 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.2 4.7 GO:1905176 response to mycophenolic acid(GO:0071505) cellular response to mycophenolic acid(GO:0071506) metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
1.2 8.2 GO:0007341 penetration of zona pellucida(GO:0007341)
1.2 3.5 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.2 5.8 GO:0080009 mRNA methylation(GO:0080009)
1.2 4.6 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
1.2 3.5 GO:0060017 parathyroid gland development(GO:0060017)
1.1 3.4 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
1.1 3.4 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
1.1 12.6 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
1.1 4.6 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
1.1 4.6 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
1.1 46.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
1.1 10.3 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
1.1 8.0 GO:0042426 choline catabolic process(GO:0042426)
1.1 3.4 GO:0019056 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
1.1 2.3 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
1.1 6.8 GO:0031642 negative regulation of myelination(GO:0031642)
1.1 2.3 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
1.1 2.2 GO:0003176 aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180)
1.1 2.2 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
1.1 1.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
1.1 1.1 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155)
1.1 7.8 GO:0097091 synaptic vesicle clustering(GO:0097091)
1.1 4.4 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
1.1 5.5 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
1.1 2.2 GO:0007418 ventral midline development(GO:0007418) cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
1.1 3.3 GO:0045588 positive regulation of gamma-delta T cell differentiation(GO:0045588)
1.1 7.7 GO:1903232 melanosome assembly(GO:1903232)
1.1 4.4 GO:0071494 cellular response to UV-C(GO:0071494)
1.1 3.3 GO:0050916 sensory perception of sweet taste(GO:0050916)
1.1 2.2 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
1.1 2.2 GO:0034227 tRNA thio-modification(GO:0034227)
1.1 3.3 GO:0002118 aggressive behavior(GO:0002118)
1.1 29.5 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
1.1 30.6 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
1.1 1.1 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
1.1 3.3 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
1.1 14.1 GO:0050932 regulation of pigment cell differentiation(GO:0050932)
1.1 5.4 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
1.1 5.4 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
1.1 6.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
1.1 3.2 GO:2000824 embryonic heart tube anterior/posterior pattern specification(GO:0035054) negative regulation of androgen receptor activity(GO:2000824)
1.1 27.7 GO:0034199 activation of protein kinase A activity(GO:0034199)
1.1 8.5 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
1.1 3.2 GO:0055075 potassium ion homeostasis(GO:0055075)
1.1 21.2 GO:0045730 respiratory burst(GO:0045730)
1.1 7.4 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
1.1 6.3 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
1.1 5.3 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
1.0 5.2 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
1.0 2.1 GO:0032474 otolith morphogenesis(GO:0032474)
1.0 8.4 GO:0032482 Rab protein signal transduction(GO:0032482)
1.0 7.3 GO:0002220 innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223)
1.0 3.1 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242) positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle transport(GO:1902805) positive regulation of synaptic vesicle recycling(GO:1903423)
1.0 4.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
1.0 5.1 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
1.0 2.0 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
1.0 3.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
1.0 17.3 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
1.0 4.1 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
1.0 3.0 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
1.0 8.1 GO:0036066 protein O-linked fucosylation(GO:0036066)
1.0 7.1 GO:0033578 protein glycosylation in Golgi(GO:0033578)
1.0 3.0 GO:0034371 chylomicron remodeling(GO:0034371)
1.0 4.0 GO:0006272 leading strand elongation(GO:0006272)
1.0 2.0 GO:0023021 termination of signal transduction(GO:0023021)
1.0 3.0 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
1.0 24.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
1.0 4.0 GO:0043307 eosinophil activation(GO:0043307)
1.0 3.0 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
1.0 4.9 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
1.0 3.0 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
1.0 5.9 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
1.0 2.9 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
1.0 3.9 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
1.0 9.7 GO:0032364 oxygen homeostasis(GO:0032364)
1.0 9.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
1.0 3.9 GO:0003335 corneocyte development(GO:0003335)
1.0 1.9 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
1.0 9.5 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
1.0 21.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.9 6.6 GO:0048266 behavioral response to pain(GO:0048266)
0.9 3.8 GO:0032053 ciliary basal body organization(GO:0032053)
0.9 5.7 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.9 3.8 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.9 2.8 GO:0019732 antifungal humoral response(GO:0019732)
0.9 5.6 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.9 18.7 GO:0097503 sialylation(GO:0097503)
0.9 2.8 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.9 14.9 GO:0035493 SNARE complex assembly(GO:0035493)
0.9 0.9 GO:0070207 protein homotrimerization(GO:0070207)
0.9 2.8 GO:0071423 thiosulfate tr