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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for LEF1

Z-value: 0.89

Motif logo

Transcription factors associated with LEF1

Gene Symbol Gene ID Gene Info
ENSG00000138795.5 lymphoid enhancer binding factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LEF1hg19_v2_chr4_-_109089573_109089585-0.229.4e-04Click!

Activity profile of LEF1 motif

Sorted Z-values of LEF1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_54074033 18.25 ENST00000373970.3
dickkopf WNT signaling pathway inhibitor 1
chr15_+_96869165 14.15 ENST00000421109.2
nuclear receptor subfamily 2, group F, member 2
chr20_+_11898507 12.12 ENST00000378226.2
BTB (POZ) domain containing 3
chr11_+_69455855 10.57 ENST00000227507.2
ENST00000536559.1
cyclin D1
chr3_-_134093395 9.84 ENST00000249883.5
angiomotin like 2
chr15_-_37392086 9.77 ENST00000561208.1
Meis homeobox 2
chr16_+_89989687 8.92 ENST00000315491.7
ENST00000555576.1
ENST00000554336.1
ENST00000553967.1
Tubulin beta-3 chain
chr14_+_54863739 8.80 ENST00000541304.1
cyclin-dependent kinase inhibitor 3
chr14_+_54863667 8.55 ENST00000335183.6
cyclin-dependent kinase inhibitor 3
chr14_+_54863682 8.23 ENST00000543789.2
ENST00000442975.2
ENST00000458126.2
ENST00000556102.2
cyclin-dependent kinase inhibitor 3
chr5_+_137514834 8.16 ENST00000508792.1
ENST00000504621.1
kinesin family member 20A
chr13_+_76334567 8.02 ENST00000321797.8
LIM domain 7
chr5_+_137514687 8.00 ENST00000394894.3
kinesin family member 20A
chr13_+_76334795 7.98 ENST00000526202.1
ENST00000465261.2
LIM domain 7
chr2_+_181845843 7.91 ENST00000602710.1
ubiquitin-conjugating enzyme E2E 3
chr13_-_45150392 7.76 ENST00000501704.2
TSC22 domain family, member 1
chr3_-_134093275 7.58 ENST00000513145.1
ENST00000422605.2
angiomotin like 2
chr12_-_118498958 7.44 ENST00000315436.3
WD repeat and SOCS box containing 2
chr7_+_16793160 7.34 ENST00000262067.4
tetraspanin 13
chr3_-_149375783 7.25 ENST00000467467.1
ENST00000460517.1
ENST00000360632.3
WW domain containing transcription regulator 1
chr2_+_201170596 6.93 ENST00000439084.1
ENST00000409718.1
spermatogenesis associated, serine-rich 2-like
chr22_-_36357671 6.91 ENST00000408983.2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr5_-_16936340 6.80 ENST00000507288.1
ENST00000513610.1
myosin X
chr2_+_201170770 6.76 ENST00000409988.3
ENST00000409385.1
spermatogenesis associated, serine-rich 2-like
chr11_-_62474803 6.59 ENST00000533982.1
ENST00000360796.5
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr5_+_34757309 6.38 ENST00000397449.1
retinoic acid induced 14
chrX_-_10588459 6.32 ENST00000380782.2
midline 1 (Opitz/BBB syndrome)
chr11_-_64013663 6.28 ENST00000392210.2
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr8_-_80993010 6.16 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
tumor protein D52
chr2_+_201171242 6.11 ENST00000360760.5
spermatogenesis associated, serine-rich 2-like
chr2_-_166060552 6.06 ENST00000283254.7
ENST00000453007.1
sodium channel, voltage-gated, type III, alpha subunit
chr1_+_93913713 6.06 ENST00000604705.1
ENST00000370253.2
formin binding protein 1-like
chr11_-_64013288 5.97 ENST00000542235.1
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr4_-_157892498 5.95 ENST00000502773.1
platelet derived growth factor C
chr5_+_140864649 5.93 ENST00000306593.1
protocadherin gamma subfamily C, 4
chr11_+_101983176 5.93 ENST00000524575.1
Yes-associated protein 1
chr9_+_71819927 5.86 ENST00000535702.1
tight junction protein 2
chr13_-_36429763 5.73 ENST00000379893.1
doublecortin-like kinase 1
chrX_-_10588595 5.71 ENST00000423614.1
ENST00000317552.4
midline 1 (Opitz/BBB syndrome)
chr12_-_16759711 5.69 ENST00000447609.1
LIM domain only 3 (rhombotin-like 2)
chr3_-_33700933 5.62 ENST00000480013.1
cytoplasmic linker associated protein 2
chr15_-_37393406 5.62 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
Meis homeobox 2
chr3_-_33686743 5.62 ENST00000333778.6
ENST00000539981.1
cytoplasmic linker associated protein 2
chrX_+_102631844 5.60 ENST00000372634.1
ENST00000299872.7
nerve growth factor receptor (TNFRSF16) associated protein 1
chr12_+_6309963 5.46 ENST00000382515.2
CD9 molecule
chr2_-_216257849 5.45 ENST00000456923.1
fibronectin 1
chr4_-_139163491 5.44 ENST00000280612.5
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr1_-_95392635 5.38 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
calponin 3, acidic
chr15_+_43985725 5.36 ENST00000413453.2
creatine kinase, mitochondrial 1A
chr12_+_69979113 5.35 ENST00000299300.6
chaperonin containing TCP1, subunit 2 (beta)
chr5_+_140797296 5.32 ENST00000398594.2
protocadherin gamma subfamily B, 7
chr15_+_57511609 5.29 ENST00000543579.1
ENST00000537840.1
ENST00000343827.3
transcription factor 12
chr1_-_225840747 5.27 ENST00000366843.2
ENST00000366844.3
enabled homolog (Drosophila)
chr4_-_111119804 5.18 ENST00000394607.3
ENST00000302274.3
ELOVL fatty acid elongase 6
chr20_+_10199468 5.18 ENST00000254976.2
ENST00000304886.2
synaptosomal-associated protein, 25kDa
chr1_-_32801825 5.14 ENST00000329421.7
MARCKS-like 1
chr1_-_54303934 5.03 ENST00000537333.1
NDC1 transmembrane nucleoporin
chr5_-_146833485 4.91 ENST00000398514.3
dihydropyrimidinase-like 3
chr2_+_201171372 4.90 ENST00000409140.3
spermatogenesis associated, serine-rich 2-like
chr17_-_46682321 4.85 ENST00000225648.3
ENST00000484302.2
homeobox B6
chr2_-_166060571 4.85 ENST00000360093.3
sodium channel, voltage-gated, type III, alpha subunit
chr8_+_80523321 4.80 ENST00000518111.1
stathmin-like 2
chr9_+_71820057 4.80 ENST00000539225.1
tight junction protein 2
chrX_+_38420783 4.79 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
tetraspanin 7
chr15_+_52311398 4.78 ENST00000261845.5
mitogen-activated protein kinase 6
chr17_-_77924627 4.77 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
TBC1 domain family, member 16
chr3_-_141747439 4.69 ENST00000467667.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr10_-_95242044 4.68 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
myoferlin
chr12_+_53491220 4.64 ENST00000548547.1
ENST00000301464.3
insulin-like growth factor binding protein 6
chr15_+_43885252 4.58 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
creatine kinase, mitochondrial 1B
chr1_-_54304212 4.58 ENST00000540001.1
NDC1 transmembrane nucleoporin
chr10_-_95241951 4.57 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
myoferlin
chr15_+_43985084 4.56 ENST00000434505.1
ENST00000411750.1
creatine kinase, mitochondrial 1A
chr1_-_177133818 4.56 ENST00000424564.2
ENST00000361833.2
astrotactin 1
chr4_-_74088800 4.56 ENST00000509867.2
ankyrin repeat domain 17
chr3_-_148804275 4.55 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
helicase-like transcription factor
chr18_-_74728998 4.55 ENST00000359645.3
ENST00000397875.3
ENST00000397869.3
ENST00000578193.1
ENST00000578873.1
ENST00000397866.4
ENST00000528160.1
ENST00000527041.1
ENST00000526111.1
ENST00000397865.5
ENST00000382582.3
myelin basic protein
chr18_-_25616519 4.44 ENST00000399380.3
cadherin 2, type 1, N-cadherin (neuronal)
chr7_+_73868439 4.42 ENST00000424337.2
GTF2I repeat domain containing 1
chr2_-_86564776 4.41 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
receptor accessory protein 1
chr2_+_234621551 4.39 ENST00000608381.1
ENST00000373414.3
UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5
chr15_-_37391614 4.38 ENST00000219869.9
Meis homeobox 2
chr4_+_146403912 4.37 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD family member 1
chr17_-_43025005 4.30 ENST00000587309.1
ENST00000593135.1
ENST00000339151.4
kinesin family member 18B
chr1_-_177134024 4.22 ENST00000367654.3
astrotactin 1
chrX_-_80457385 4.21 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
high mobility group nucleosome binding domain 5
chr1_+_166808692 4.21 ENST00000367876.4
pogo transposable element with KRAB domain
chr18_+_3449821 4.21 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGFB-induced factor homeobox 1
chr3_-_58563094 4.18 ENST00000464064.1
family with sequence similarity 107, member A
chr7_-_99698338 4.14 ENST00000354230.3
ENST00000425308.1
minichromosome maintenance complex component 7
chr12_+_79258547 4.13 ENST00000457153.2
synaptotagmin I
chr14_+_29234870 4.12 ENST00000382535.3
forkhead box G1
chr6_-_56707943 4.09 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
dystonin
chr1_+_68150744 4.09 ENST00000370986.4
ENST00000370985.3
growth arrest and DNA-damage-inducible, alpha
chr1_+_82266053 4.00 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
latrophilin 2
chr1_-_54303949 3.98 ENST00000234725.8
NDC1 transmembrane nucleoporin
chrX_-_10645773 3.97 ENST00000453318.2
midline 1 (Opitz/BBB syndrome)
chr2_-_2334888 3.92 ENST00000428368.2
ENST00000399161.2
myelin transcription factor 1-like
chr15_+_63335899 3.89 ENST00000561266.1
tropomyosin 1 (alpha)
chr8_-_22089845 3.89 ENST00000454243.2
phytanoyl-CoA 2-hydroxylase interacting protein
chr14_-_105444694 3.86 ENST00000333244.5
AHNAK nucleoprotein 2
chr7_-_80548667 3.86 ENST00000265361.3
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr8_-_22089533 3.86 ENST00000321613.3
phytanoyl-CoA 2-hydroxylase interacting protein
chr8_+_85095769 3.79 ENST00000518566.1
RALY RNA binding protein-like
chr13_-_67802549 3.78 ENST00000328454.5
ENST00000377865.2
protocadherin 9
chr1_+_87797351 3.75 ENST00000370542.1
LIM domain only 4
chr5_+_140749803 3.71 ENST00000576222.1
protocadherin gamma subfamily B, 3
chr16_+_68678892 3.70 ENST00000429102.2
cadherin 3, type 1, P-cadherin (placental)
chr3_-_79816965 3.67 ENST00000464233.1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr1_+_164528866 3.65 ENST00000420696.2
pre-B-cell leukemia homeobox 1
chr1_-_38061522 3.62 ENST00000373062.3
guanine nucleotide binding protein-like 2 (nucleolar)
chr8_-_145642267 3.56 ENST00000301305.3
solute carrier family 39 (zinc transporter), member 4
chr7_-_27213893 3.51 ENST00000283921.4
homeobox A10
chr1_+_6845384 3.51 ENST00000303635.7
calmodulin binding transcription activator 1
chr7_+_73868220 3.50 ENST00000455841.2
GTF2I repeat domain containing 1
chr7_-_27219849 3.44 ENST00000396344.4
homeobox A10
chr10_+_114710211 3.43 ENST00000349937.2
ENST00000369397.4
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr2_+_201171064 3.42 ENST00000451764.2
spermatogenesis associated, serine-rich 2-like
chr16_+_6069586 3.41 ENST00000547372.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr9_+_504674 3.34 ENST00000382297.2
KN motif and ankyrin repeat domains 1
chr6_+_32146131 3.33 ENST00000375094.3
ring finger protein 5, E3 ubiquitin protein ligase
chr1_-_115292591 3.22 ENST00000438362.2
cold shock domain containing E1, RNA-binding
chr14_+_101299520 3.19 ENST00000455531.1
maternally expressed 3 (non-protein coding)
chr16_+_68678739 3.16 ENST00000264012.4
cadherin 3, type 1, P-cadherin (placental)
chr16_+_6069072 3.15 ENST00000547605.1
ENST00000550418.1
ENST00000553186.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr11_-_57298187 3.15 ENST00000525158.1
ENST00000257245.4
ENST00000525587.1
translocase of inner mitochondrial membrane 10 homolog (yeast)
chr1_-_211752073 3.10 ENST00000367001.4
solute carrier family 30 (zinc transporter), member 1
chr5_+_112074029 3.09 ENST00000512211.2
adenomatous polyposis coli
chr6_+_114178512 3.08 ENST00000368635.4
myristoylated alanine-rich protein kinase C substrate
chr18_+_55888767 3.05 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr14_+_56078695 3.01 ENST00000416613.1
kinectin 1 (kinesin receptor)
chr5_+_140729649 3.01 ENST00000523390.1
protocadherin gamma subfamily B, 1
chrX_+_119737806 3.01 ENST00000371317.5
malignant T cell amplified sequence 1
chr11_-_111794446 3.00 ENST00000527950.1
crystallin, alpha B
chr4_+_83351791 2.99 ENST00000509635.1
enolase-phosphatase 1
chr2_-_170681324 2.97 ENST00000409340.1
methyltransferase like 5
chr14_+_61201445 2.96 ENST00000261245.4
ENST00000539616.2
MNAT CDK-activating kinase assembly factor 1
chr7_+_56119323 2.96 ENST00000275603.4
ENST00000335503.3
ENST00000540286.1
chaperonin containing TCP1, subunit 6A (zeta 1)
chr6_-_153304148 2.94 ENST00000229758.3
F-box protein 5
chr10_+_114709999 2.94 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr2_-_9143786 2.93 ENST00000462696.1
ENST00000305997.3
membrane bound O-acyltransferase domain containing 2
chr11_+_57529234 2.92 ENST00000360682.6
ENST00000361796.4
ENST00000529526.1
ENST00000426142.2
ENST00000399050.4
ENST00000361391.6
ENST00000361332.4
ENST00000532463.1
ENST00000529986.1
ENST00000358694.6
ENST00000532787.1
ENST00000533667.1
ENST00000532649.1
ENST00000528621.1
ENST00000530748.1
ENST00000428599.2
ENST00000527467.1
ENST00000528232.1
ENST00000531014.1
ENST00000526772.1
ENST00000529873.1
ENST00000525902.1
ENST00000532844.1
ENST00000526357.1
ENST00000530094.1
ENST00000415361.2
ENST00000532245.1
ENST00000534579.1
ENST00000526938.1
catenin (cadherin-associated protein), delta 1
chr14_-_71107921 2.86 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
chr6_+_134274322 2.84 ENST00000367871.1
ENST00000237264.4
TBP-like 1
chr4_+_83351715 2.83 ENST00000273920.3
enolase-phosphatase 1
chr15_+_80696666 2.83 ENST00000303329.4
aryl-hydrocarbon receptor nuclear translocator 2
chr2_-_211341411 2.82 ENST00000233714.4
ENST00000443314.1
ENST00000441020.3
ENST00000450366.2
ENST00000431941.2
LanC lantibiotic synthetase component C-like 1 (bacterial)
chr12_+_54422142 2.82 ENST00000243108.4
homeobox C6
chr12_+_104359576 2.82 ENST00000392872.3
ENST00000436021.2
thymine-DNA glycosylase
chr3_-_141747950 2.81 ENST00000497579.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr4_+_20255123 2.78 ENST00000504154.1
ENST00000273739.5
slit homolog 2 (Drosophila)
chr11_+_120255997 2.77 ENST00000532993.1
Rho guanine nucleotide exchange factor (GEF) 12
chr1_+_155036204 2.76 ENST00000368409.3
ENST00000359751.4
ENST00000427683.2
ENST00000556931.1
ENST00000505139.1
ephrin-A4
ephrin-A3
Ephrin-A3; Uncharacterized protein; cDNA FLJ57652, highly similar to Ephrin-A3
chr17_-_685559 2.76 ENST00000301329.6
glyoxalase domain containing 4
chr3_+_173302222 2.74 ENST00000361589.4
neuroligin 1
chr2_-_176046391 2.74 ENST00000392541.3
ENST00000409194.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr5_+_95066823 2.72 ENST00000506817.1
ENST00000379982.3
Rho-related BTB domain containing 3
chr1_-_115259337 2.72 ENST00000369535.4
neuroblastoma RAS viral (v-ras) oncogene homolog
chr10_+_123923205 2.68 ENST00000369004.3
ENST00000260733.3
transforming, acidic coiled-coil containing protein 2
chr13_+_37581115 2.68 ENST00000481013.1
exosome component 8
chr20_-_32891151 2.67 ENST00000217426.2
adenosylhomocysteinase
chr5_-_176900610 2.67 ENST00000477391.2
ENST00000393565.1
ENST00000309007.5
drebrin 1
chr1_+_87794150 2.65 ENST00000370544.5
LIM domain only 4
chr7_-_47621736 2.64 ENST00000311160.9
tensin 3
chr14_-_60097297 2.63 ENST00000395090.1
reticulon 1
chr7_+_23146271 2.60 ENST00000545771.1
kelch-like family member 7
chrX_-_109683446 2.58 ENST00000372057.1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr11_+_114128522 2.57 ENST00000535401.1
nicotinamide N-methyltransferase
chr16_+_68679193 2.56 ENST00000581171.1
cadherin 3, type 1, P-cadherin (placental)
chr5_-_146435501 2.54 ENST00000336640.6
protein phosphatase 2, regulatory subunit B, beta
chrX_-_43832711 2.53 ENST00000378062.5
Norrie disease (pseudoglioma)
chr10_-_735553 2.53 ENST00000280886.6
ENST00000423550.1
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr17_-_685493 2.52 ENST00000536578.1
ENST00000301328.5
ENST00000576419.1
glyoxalase domain containing 4
chr2_-_224467093 2.52 ENST00000305409.2
secretogranin II
chr12_-_16761007 2.51 ENST00000354662.1
ENST00000441439.2
LIM domain only 3 (rhombotin-like 2)
chr12_+_54378923 2.50 ENST00000303460.4
homeobox C10
chr6_+_64282447 2.49 ENST00000370650.2
ENST00000578299.1
protein tyrosine phosphatase type IVA, member 1
chr7_+_69064300 2.48 ENST00000342771.4
autism susceptibility candidate 2
chr18_-_31802056 2.44 ENST00000538587.1
nucleolar protein 4
chr2_+_149632783 2.44 ENST00000435030.1
kinesin family member 5C
chr7_-_137028498 2.43 ENST00000393083.2
pleiotrophin
chr16_+_57673430 2.42 ENST00000540164.2
ENST00000568531.1
G protein-coupled receptor 56
chr10_-_104192405 2.42 ENST00000369937.4
CUE domain containing 2
chr5_-_138210977 2.37 ENST00000274711.6
ENST00000521094.2
leucine rich repeat transmembrane neuronal 2
chr2_-_26205340 2.35 ENST00000264712.3
kinesin family member 3C
chr5_+_141346385 2.33 ENST00000513019.1
ENST00000356143.1
ring finger protein 14
chr13_+_52598827 2.32 ENST00000521776.2
UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr3_+_123813509 2.31 ENST00000460856.1
ENST00000240874.3
kalirin, RhoGEF kinase
chr20_+_60718785 2.31 ENST00000421564.1
ENST00000450482.1
ENST00000331758.3
synovial sarcoma translocation gene on chromosome 18-like 1
chr18_-_53089723 2.30 ENST00000561992.1
ENST00000562512.2
transcription factor 4
chrX_+_54835493 2.29 ENST00000396224.1
melanoma antigen family D, 2
chr5_+_92919043 2.28 ENST00000327111.3
nuclear receptor subfamily 2, group F, member 1
chr15_+_50474385 2.25 ENST00000267842.5
solute carrier family 27 (fatty acid transporter), member 2
chr5_+_179921430 2.25 ENST00000393356.1
CCR4-NOT transcription complex, subunit 6
chr5_-_177580777 2.23 ENST00000314397.4
NHP2 ribonucleoprotein
chr17_-_37934466 2.22 ENST00000583368.1
IKAROS family zinc finger 3 (Aiolos)
chr7_+_116312411 2.21 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
met proto-oncogene
chr11_-_62432641 2.21 ENST00000528405.1
ENST00000524958.1
ENST00000525675.1
Uncharacterized protein
chromosome 11 open reading frame 48
chr5_+_179921344 2.21 ENST00000261951.4
CCR4-NOT transcription complex, subunit 6
chr1_-_94079648 2.20 ENST00000370247.3
breast cancer anti-estrogen resistance 3

Network of associatons between targets according to the STRING database.

First level regulatory network of LEF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.7 20.2 GO:0009996 negative regulation of cell fate specification(GO:0009996)
4.5 13.6 GO:0030474 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
4.0 16.2 GO:0009956 radial pattern formation(GO:0009956)
3.1 9.4 GO:0060901 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
2.2 6.5 GO:0050923 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
1.8 5.4 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
1.8 5.4 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
1.7 5.1 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
1.6 7.9 GO:0014886 transition between slow and fast fiber(GO:0014886)
1.5 4.6 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
1.5 6.1 GO:1902544 oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544)
1.4 7.2 GO:1901631 positive regulation of presynaptic membrane organization(GO:1901631) positive regulation of synaptic vesicle clustering(GO:2000809)
1.4 11.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
1.4 4.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
1.4 4.1 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
1.4 8.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
1.3 7.7 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
1.3 6.3 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
1.2 16.0 GO:0035372 protein localization to microtubule(GO:0035372)
1.2 4.8 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
1.2 6.9 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
1.1 4.6 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
1.1 3.3 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
1.1 13.1 GO:0001778 plasma membrane repair(GO:0001778)
1.1 10.7 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
1.1 10.6 GO:0070141 response to UV-A(GO:0070141)
1.0 5.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
1.0 4.0 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
1.0 3.0 GO:0002188 translation reinitiation(GO:0002188)
0.9 13.2 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.9 4.6 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.9 9.9 GO:0006600 creatine metabolic process(GO:0006600)
0.9 16.2 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.9 4.4 GO:0070980 biphenyl catabolic process(GO:0070980)
0.9 5.2 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.8 3.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.7 2.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.7 2.8 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.7 2.7 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.7 2.7 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.7 6.7 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.6 3.2 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.6 4.5 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.6 5.8 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.6 3.9 GO:0003350 pulmonary myocardium development(GO:0003350)
0.6 6.4 GO:0042659 regulation of cell fate specification(GO:0042659)
0.6 2.5 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.6 2.5 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.6 1.8 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.6 2.3 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.5 4.4 GO:0002051 osteoblast fate commitment(GO:0002051)
0.5 3.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.5 2.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.5 3.9 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.5 2.4 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.5 1.9 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.5 6.6 GO:0030913 paranodal junction assembly(GO:0030913)
0.5 3.2 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.5 4.1 GO:0008090 retrograde axonal transport(GO:0008090)
0.4 0.9 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.4 2.7 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.4 2.2 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.4 2.2 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.4 2.1 GO:0035617 stress granule disassembly(GO:0035617)
0.4 4.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.4 1.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.4 2.0 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.4 10.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.4 1.9 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.4 8.0 GO:0051764 actin crosslink formation(GO:0051764)
0.4 1.1 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.4 12.0 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.4 4.8 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.4 1.4 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.3 3.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.3 1.4 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.3 13.5 GO:0035329 hippo signaling(GO:0035329)
0.3 1.3 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.3 0.7 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
0.3 1.3 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.3 0.9 GO:0031133 regulation of axon diameter(GO:0031133)
0.3 30.2 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.3 3.0 GO:1904871 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.3 8.2 GO:0010669 epithelial structure maintenance(GO:0010669)
0.3 4.4 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.3 1.5 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.3 6.6 GO:0034389 lipid particle organization(GO:0034389)
0.3 6.1 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.3 1.3 GO:0051013 microtubule severing(GO:0051013)
0.3 19.0 GO:0008542 visual learning(GO:0008542)
0.3 6.0 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.3 1.0 GO:2000320 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.3 1.8 GO:0007144 female meiosis I(GO:0007144)
0.3 2.8 GO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.2 4.8 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.2 14.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.2 0.7 GO:0032899 regulation of nucleoside transport(GO:0032242) regulation of neurotrophin production(GO:0032899) negative regulation of neurotrophin production(GO:0032900)
0.2 11.2 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.2 2.4 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.2 2.6 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.2 4.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.2 2.5 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.2 0.8 GO:0035881 amacrine cell differentiation(GO:0035881)
0.2 2.0 GO:0010265 SCF complex assembly(GO:0010265)
0.2 1.8 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.2 0.6 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.2 0.8 GO:0035973 aggrephagy(GO:0035973)
0.2 3.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 0.4 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.2 10.7 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.2 2.2 GO:0070307 lens fiber cell development(GO:0070307)
0.2 0.9 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.2 7.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.2 0.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 0.7 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.2 0.8 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.2 2.1 GO:0071625 vocalization behavior(GO:0071625)
0.2 1.1 GO:0060339 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.2 4.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.2 1.7 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.2 1.1 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 4.2 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.1 1.4 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.6 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.6 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 18.4 GO:0048813 dendrite morphogenesis(GO:0048813)
0.1 0.8 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 1.1 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.1 2.0 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 2.1 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.9 GO:1903232 melanosome assembly(GO:1903232)
0.1 1.4 GO:0007413 axonal fasciculation(GO:0007413)
0.1 1.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.8 GO:1990564 protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.6 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 3.2 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.1 0.8 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 1.4 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 0.2 GO:0048880 sensory system development(GO:0048880)
0.1 0.4 GO:0035983 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.1 0.8 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.1 2.2 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 0.5 GO:0030879 mammary gland development(GO:0030879)
0.1 3.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.5 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.5 GO:0097338 response to clozapine(GO:0097338)
0.1 3.5 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 0.9 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.1 0.6 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.1 5.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 3.1 GO:0006833 water transport(GO:0006833)
0.1 1.0 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.4 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.1 1.0 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.2 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 0.2 GO:0021553 olfactory nerve development(GO:0021553) ureteric bud invasion(GO:0072092)
0.1 1.2 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 1.3 GO:0006020 inositol metabolic process(GO:0006020)
0.1 2.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.7 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 2.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 2.7 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.1 0.6 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.1 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 10.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 2.1 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.1 4.2 GO:0001558 regulation of cell growth(GO:0001558)
0.1 1.3 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.1 2.3 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.1 0.9 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 3.4 GO:1903146 regulation of mitophagy(GO:1903146)
0.1 2.0 GO:0048286 lung alveolus development(GO:0048286)
0.1 0.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.1 1.5 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.9 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.1 0.8 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 0.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 1.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.4 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 2.3 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 2.1 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.1 1.7 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 1.6 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 2.8 GO:0030183 B cell differentiation(GO:0030183)
0.0 2.8 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.8 GO:0019054 modulation by virus of host process(GO:0019054)
0.0 1.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.4 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.0 1.2 GO:0050850 positive regulation of calcium-mediated signaling(GO:0050850)
0.0 0.8 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.8 GO:0048665 neuron fate specification(GO:0048665)
0.0 3.8 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.0 2.9 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 1.0 GO:0014047 glutamate secretion(GO:0014047)
0.0 14.3 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.7 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 1.4 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.0 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 1.7 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 1.7 GO:0006968 cellular defense response(GO:0006968)
0.0 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.7 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 1.9 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.8 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.8 GO:0019835 cytolysis(GO:0019835)
0.0 1.3 GO:0006497 protein lipidation(GO:0006497)
0.0 0.4 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 2.3 GO:0051028 mRNA transport(GO:0051028)
0.0 0.4 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 2.3 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 4.6 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 0.1 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 1.4 GO:0034101 erythrocyte homeostasis(GO:0034101)
0.0 1.1 GO:0097581 lamellipodium organization(GO:0097581)
0.0 0.3 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.1 GO:0033198 response to ATP(GO:0033198)
0.0 0.5 GO:0006301 postreplication repair(GO:0006301)
0.0 0.4 GO:0030850 prostate gland development(GO:0030850)
0.0 0.3 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.3 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 13.6 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
1.3 5.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
1.2 5.9 GO:0071148 TEAD-1-YAP complex(GO:0071148)
1.1 11.2 GO:0045180 basal cortex(GO:0045180)
1.1 6.3 GO:0090661 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
1.0 4.1 GO:0031673 H zone(GO:0031673)
0.8 4.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.7 2.0 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.7 11.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.7 4.6 GO:0033269 internode region of axon(GO:0033269)
0.6 7.5 GO:0016342 catenin complex(GO:0016342)
0.6 1.8 GO:1903349 omegasome membrane(GO:1903349)
0.5 1.1 GO:0042025 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.5 4.3 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.5 1.6 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.5 9.5 GO:0032433 filopodium tip(GO:0032433)
0.5 2.3 GO:0071565 nBAF complex(GO:0071565)
0.5 4.5 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.4 8.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.4 5.4 GO:0005577 fibrinogen complex(GO:0005577)
0.4 1.2 GO:0018444 translation release factor complex(GO:0018444)
0.4 3.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.4 3.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.4 4.6 GO:0035253 ciliary rootlet(GO:0035253)
0.3 2.9 GO:0005915 zonula adherens(GO:0005915)
0.3 4.1 GO:0042555 MCM complex(GO:0042555)
0.3 5.3 GO:0032059 bleb(GO:0032059)
0.3 3.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.3 3.0 GO:0005675 holo TFIIH complex(GO:0005675)
0.3 7.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.3 1.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 2.8 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.3 4.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.3 2.5 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.3 13.5 GO:0005871 kinesin complex(GO:0005871)
0.3 0.8 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.2 1.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 2.7 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.2 1.9 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.2 36.2 GO:0005923 bicellular tight junction(GO:0005923)
0.2 4.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 12.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 4.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.2 1.7 GO:0070761 pre-snoRNP complex(GO:0070761)
0.2 0.8 GO:0032279 asymmetric synapse(GO:0032279)
0.2 3.1 GO:0043073 germ cell nucleus(GO:0043073)
0.2 4.6 GO:0071564 npBAF complex(GO:0071564)
0.2 3.0 GO:0097512 cardiac myofibril(GO:0097512)
0.2 6.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 0.9 GO:0031905 early endosome lumen(GO:0031905)
0.2 1.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 2.5 GO:0031045 dense core granule(GO:0031045)
0.2 20.0 GO:0005875 microtubule associated complex(GO:0005875)
0.2 2.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.3 GO:0061574 ASAP complex(GO:0061574)
0.1 0.6 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.1 2.1 GO:0005883 neurofilament(GO:0005883)
0.1 14.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 2.7 GO:0005921 gap junction(GO:0005921)
0.1 5.5 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 0.8 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 5.2 GO:0031941 filamentous actin(GO:0031941)
0.1 17.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 2.6 GO:0044291 cell-cell contact zone(GO:0044291)
0.1 2.2 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.6 GO:0097422 tubular endosome(GO:0097422)
0.1 8.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 15.9 GO:0031901 early endosome membrane(GO:0031901)
0.1 8.2 GO:0030315 T-tubule(GO:0030315)
0.1 8.1 GO:0005901 caveola(GO:0005901)
0.1 0.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 0.8 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.8 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 5.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.7 GO:0042382 paraspeckles(GO:0042382)
0.1 0.7 GO:0034464 BBSome(GO:0034464)
0.1 2.3 GO:0032040 small-subunit processome(GO:0032040)
0.1 2.7 GO:0032590 dendrite membrane(GO:0032590)
0.1 1.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.9 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 14.5 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.1 1.1 GO:0031143 pseudopodium(GO:0031143)
0.1 3.1 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.3 GO:0032156 septin cytoskeleton(GO:0032156)
0.1 0.3 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 22.5 GO:0031252 cell leading edge(GO:0031252)
0.1 6.3 GO:0043204 perikaryon(GO:0043204)
0.1 12.3 GO:0005819 spindle(GO:0005819)
0.1 3.3 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 2.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 9.7 GO:0005938 cell cortex(GO:0005938)
0.0 0.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 1.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 2.3 GO:0005771 multivesicular body(GO:0005771)
0.0 0.6 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.8 GO:0005776 autophagosome(GO:0005776)
0.0 4.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.3 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.9 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 3.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.0 GO:0048786 presynaptic active zone(GO:0048786)
0.0 20.7 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 2.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 8.1 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.3 GO:0005902 microvillus(GO:0005902)
0.0 1.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 5.0 GO:0005874 microtubule(GO:0005874)
0.0 2.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 17.4 GO:0005730 nucleolus(GO:0005730)
0.0 0.5 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.8 GO:0018995 host(GO:0018995) host cell(GO:0043657)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.6 GO:0015030 Cajal body(GO:0015030)
0.0 2.6 GO:0016604 nuclear body(GO:0016604)
0.0 3.5 GO:0016607 nuclear speck(GO:0016607)
0.0 5.2 GO:0019866 organelle inner membrane(GO:0019866)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.1 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
1.7 18.6 GO:0039706 co-receptor binding(GO:0039706)
1.2 9.9 GO:0004111 creatine kinase activity(GO:0004111)
1.2 9.5 GO:0035374 chondroitin sulfate binding(GO:0035374)
1.1 2.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
1.1 5.4 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
1.1 6.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.9 5.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.8 4.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.8 3.2 GO:0038025 reelin receptor activity(GO:0038025)
0.8 6.8 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.7 8.2 GO:0030274 LIM domain binding(GO:0030274)
0.7 1.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.7 18.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.6 2.6 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.6 3.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.6 27.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.6 2.3 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.5 2.2 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.5 1.6 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.5 2.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.5 5.1 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.5 3.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.5 20.7 GO:0001972 retinoic acid binding(GO:0001972)
0.5 13.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.5 2.8 GO:0043237 laminin-1 binding(GO:0043237)
0.5 11.1 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.5 4.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.5 4.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.4 2.7 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.4 3.0 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.4 1.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.4 2.9 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.4 5.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.4 1.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.4 2.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.4 3.9 GO:0008430 selenium binding(GO:0008430)
0.4 6.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.3 1.4 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.3 3.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.3 1.7 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.3 1.3 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.3 11.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.3 5.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.3 4.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.3 2.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.3 3.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.3 3.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.3 6.0 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.3 11.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.3 2.1 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.3 2.0 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.3 5.3 GO:0035497 cAMP response element binding(GO:0035497)
0.3 1.3 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.2 20.2 GO:0003777 microtubule motor activity(GO:0003777)
0.2 1.0 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2 3.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 6.9 GO:0070064 proline-rich region binding(GO:0070064)
0.2 0.9 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.2 0.9 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.2 1.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 9.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 4.8 GO:0004707 MAP kinase activity(GO:0004707)
0.2 5.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2 1.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.2 1.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 2.7 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.2 5.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 2.8 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.2 3.4 GO:0031005 filamin binding(GO:0031005)
0.2 6.8 GO:0017091 AU-rich element binding(GO:0017091)
0.2 1.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.2 0.9 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.2 3.1 GO:0015250 water channel activity(GO:0015250)
0.2 2.5 GO:0045499 chemorepellent activity(GO:0045499)
0.2 7.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 2.8 GO:0043295 glutathione binding(GO:0043295)
0.2 0.8 GO:0070905 serine binding(GO:0070905)
0.2 2.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 1.2 GO:0019966 interleukin-1 binding(GO:0019966)
0.2 2.0 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 5.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 2.7 GO:0005522 profilin binding(GO:0005522)
0.1 2.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 4.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.7 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 0.8 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 1.7 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 1.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 0.7 GO:0005119 smoothened binding(GO:0005119)
0.1 0.6 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 5.4 GO:0016504 peptidase activator activity(GO:0016504)
0.1 3.1 GO:0035064 methylated histone binding(GO:0035064)
0.1 4.0 GO:0005109 frizzled binding(GO:0005109)
0.1 1.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 1.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 2.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.6 GO:0034452 dynactin binding(GO:0034452)
0.1 3.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 2.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 6.1 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 1.8 GO:0070410 co-SMAD binding(GO:0070410)
0.1 4.3 GO:0005080 protein kinase C binding(GO:0005080)
0.1 4.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 1.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 2.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 2.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 29.8 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 3.5 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 3.0 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 3.3 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 11.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 19.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 0.8 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 0.4 GO:0098821 BMP receptor activity(GO:0098821)
0.1 0.9 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1 1.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.9 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 1.0 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.6 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 4.0 GO:0008565 protein transporter activity(GO:0008565)
0.0 2.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.4 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.2 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 4.9 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 4.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 9.2 GO:0045296 cadherin binding(GO:0045296)
0.0 1.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 1.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 4.7 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 1.9 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 1.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 4.1 GO:0003924 GTPase activity(GO:0003924)
0.0 2.2 GO:0008168 methyltransferase activity(GO:0008168)
0.0 0.1 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 2.5 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.9 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.5 GO:0002039 p53 binding(GO:0002039)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.8 GO:0005179 hormone activity(GO:0005179)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 18.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.6 10.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.4 23.9 PID PLK1 PATHWAY PLK1 signaling events
0.2 4.4 PID ALK2 PATHWAY ALK2 signaling events
0.2 10.2 PID ATR PATHWAY ATR signaling pathway
0.2 2.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.2 4.5 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.2 3.0 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.2 6.1 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 4.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 12.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 4.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 6.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 5.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 4.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 4.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 4.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 8.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 4.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 9.6 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 4.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 7.5 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 4.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 8.2 PID E2F PATHWAY E2F transcription factor network
0.1 10.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 5.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 3.9 PID MYC PATHWAY C-MYC pathway
0.1 1.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 7.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 8.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 0.8 PID TNF PATHWAY TNF receptor signaling pathway
0.1 5.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 3.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.0 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 1.1 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.7 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.8 PID INSULIN PATHWAY Insulin Pathway
0.0 1.4 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.9 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 41.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
1.3 16.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.8 20.6 REACTOME KINESINS Genes involved in Kinesins
0.6 17.2 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.5 16.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.5 9.3 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.4 6.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.4 9.2 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.3 6.1 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.3 6.0 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.3 2.7 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.3 3.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.3 5.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.3 4.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 3.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.2 5.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 5.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 5.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 5.1 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.2 11.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.2 2.7 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.2 2.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 3.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 4.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.2 1.7 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.2 6.3 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.2 4.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 4.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 6.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 5.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 2.9 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 2.7 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 8.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 5.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 5.0 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 1.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 3.2 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 2.0 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 3.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 17.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 2.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 3.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.6 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.9 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 1.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 2.5 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 1.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 4.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.1 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.1 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 1.3 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.0 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis