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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for MYBL2
Z-value: 2.21
Motif logo
Transcription factors associated with MYBL2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
MYBL2
|
ENSG00000101057.11 | MYB proto-oncogene like 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| MYBL2 | hg19_v2_chr20_+_42295745_42295797 | 0.56 | 3.7e-19 | Click! |
Activity profile of MYBL2 motif
Sorted Z-values of MYBL2 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of MYBL2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 16.3 | 65.3 | GO:0090579 | transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579) |
| 15.8 | 47.3 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
| 13.6 | 40.9 | GO:1900195 | spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195) |
| 11.1 | 44.5 | GO:0036228 | protein targeting to nuclear inner membrane(GO:0036228) |
| 10.8 | 43.1 | GO:0046035 | CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035) |
| 10.1 | 30.4 | GO:1990022 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 8.5 | 76.4 | GO:0043570 | maintenance of DNA repeat elements(GO:0043570) |
| 8.1 | 80.9 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 6.7 | 93.4 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 6.1 | 49.1 | GO:0060699 | regulation of endoribonuclease activity(GO:0060699) |
| 5.5 | 27.4 | GO:0090306 | spindle assembly involved in meiosis(GO:0090306) |
| 5.5 | 54.8 | GO:0000972 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972) |
| 5.4 | 32.4 | GO:0019060 | intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708) |
| 5.3 | 32.1 | GO:2000825 | positive regulation of androgen receptor activity(GO:2000825) |
| 5.0 | 29.8 | GO:0019249 | lactate biosynthetic process(GO:0019249) |
| 4.9 | 44.5 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
| 4.7 | 37.6 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
| 4.6 | 18.4 | GO:0019747 | regulation of isoprenoid metabolic process(GO:0019747) |
| 4.5 | 13.4 | GO:0014016 | neuroblast differentiation(GO:0014016) |
| 4.4 | 8.9 | GO:0044211 | CTP salvage(GO:0044211) |
| 4.4 | 8.8 | GO:0038026 | reelin-mediated signaling pathway(GO:0038026) |
| 4.3 | 51.9 | GO:0015074 | DNA integration(GO:0015074) |
| 4.3 | 12.8 | GO:0009051 | pentose-phosphate shunt, oxidative branch(GO:0009051) |
| 4.0 | 11.9 | GO:1901535 | regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536) regulation of genetic imprinting(GO:2000653) |
| 3.9 | 11.7 | GO:2001245 | regulation of phosphatidylcholine biosynthetic process(GO:2001245) |
| 3.9 | 7.7 | GO:0097695 | establishment of RNA localization to telomere(GO:0097694) establishment of macromolecular complex localization to telomere(GO:0097695) |
| 3.8 | 34.1 | GO:0030091 | protein repair(GO:0030091) |
| 3.7 | 11.2 | GO:0036333 | hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772) |
| 3.7 | 63.5 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
| 3.5 | 56.5 | GO:0000338 | protein deneddylation(GO:0000338) |
| 3.5 | 65.8 | GO:0000022 | mitotic spindle elongation(GO:0000022) |
| 3.3 | 90.2 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 3.3 | 13.1 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 3.2 | 9.6 | GO:0044209 | AMP salvage(GO:0044209) |
| 3.2 | 373.7 | GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) |
| 3.2 | 15.8 | GO:1905098 | negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
| 3.0 | 12.2 | GO:0043981 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
| 3.0 | 14.8 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
| 2.9 | 11.6 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 2.9 | 8.6 | GO:1904751 | positive regulation of protein localization to nucleolus(GO:1904751) |
| 2.7 | 21.7 | GO:0015866 | ADP transport(GO:0015866) |
| 2.7 | 16.2 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
| 2.7 | 24.0 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 2.5 | 27.8 | GO:0035360 | positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360) |
| 2.5 | 4.9 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
| 2.5 | 12.3 | GO:0090649 | response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) |
| 2.5 | 12.3 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 2.4 | 94.6 | GO:2000816 | negative regulation of mitotic sister chromatid separation(GO:2000816) |
| 2.1 | 34.3 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 2.1 | 31.9 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 2.1 | 6.3 | GO:0060152 | peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152) |
| 2.1 | 6.2 | GO:0046521 | sphingoid catabolic process(GO:0046521) |
| 2.1 | 20.7 | GO:0000492 | box C/D snoRNP assembly(GO:0000492) |
| 2.0 | 6.0 | GO:0071048 | generation of catalytic spliceosome for second transesterification step(GO:0000350) nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048) |
| 2.0 | 6.0 | GO:0006425 | glutaminyl-tRNA aminoacylation(GO:0006425) |
| 2.0 | 13.8 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 1.9 | 13.5 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 1.9 | 7.6 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
| 1.9 | 17.0 | GO:0006089 | lactate metabolic process(GO:0006089) |
| 1.9 | 7.5 | GO:0021564 | vagus nerve development(GO:0021564) |
| 1.9 | 97.0 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 1.9 | 5.6 | GO:0019482 | purine nucleobase catabolic process(GO:0006145) beta-alanine metabolic process(GO:0019482) |
| 1.9 | 46.4 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 1.8 | 7.4 | GO:1903566 | positive regulation of protein localization to cilium(GO:1903566) |
| 1.8 | 35.0 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
| 1.8 | 7.3 | GO:0046833 | positive regulation of RNA export from nucleus(GO:0046833) |
| 1.8 | 38.3 | GO:0046931 | pore complex assembly(GO:0046931) |
| 1.8 | 32.6 | GO:1990001 | inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001) |
| 1.8 | 23.4 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 1.8 | 14.4 | GO:1900004 | negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572) |
| 1.7 | 27.7 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
| 1.7 | 15.3 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
| 1.7 | 5.0 | GO:0042264 | peptidyl-aspartic acid hydroxylation(GO:0042264) |
| 1.7 | 8.3 | GO:0000710 | meiotic mismatch repair(GO:0000710) |
| 1.7 | 13.3 | GO:0032790 | ribosome disassembly(GO:0032790) |
| 1.6 | 3.2 | GO:1903423 | positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423) |
| 1.6 | 11.1 | GO:0031118 | rRNA pseudouridine synthesis(GO:0031118) |
| 1.6 | 44.1 | GO:0061641 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 1.6 | 9.4 | GO:1903756 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 1.6 | 17.2 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) |
| 1.5 | 4.6 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
| 1.5 | 21.4 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 1.5 | 22.4 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
| 1.5 | 7.4 | GO:0008588 | release of cytoplasmic sequestered NF-kappaB(GO:0008588) |
| 1.4 | 24.2 | GO:0032802 | low-density lipoprotein particle receptor catabolic process(GO:0032802) |
| 1.4 | 21.1 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 1.4 | 2.8 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 1.4 | 30.2 | GO:0048255 | mRNA stabilization(GO:0048255) |
| 1.3 | 4.0 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 1.3 | 6.4 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 1.3 | 6.4 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 1.3 | 7.6 | GO:1901096 | regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098) |
| 1.3 | 7.6 | GO:0001880 | Mullerian duct regression(GO:0001880) |
| 1.3 | 8.8 | GO:0089700 | protein kinase D signaling(GO:0089700) |
| 1.2 | 7.5 | GO:0030950 | establishment or maintenance of actin cytoskeleton polarity(GO:0030950) |
| 1.2 | 3.6 | GO:0061357 | positive regulation of Wnt protein secretion(GO:0061357) |
| 1.2 | 10.6 | GO:0006264 | mitochondrial DNA replication(GO:0006264) |
| 1.2 | 4.7 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 1.2 | 13.9 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 1.1 | 5.5 | GO:0052199 | negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199) negative regulation by host of symbiont molecular function(GO:0052405) |
| 1.1 | 3.2 | GO:0046010 | positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010) |
| 1.1 | 6.4 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
| 1.1 | 5.3 | GO:0061767 | negative regulation of lung blood pressure(GO:0061767) |
| 1.0 | 15.7 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 1.0 | 5.1 | GO:0070980 | biphenyl catabolic process(GO:0070980) |
| 1.0 | 13.0 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 1.0 | 3.0 | GO:0060437 | lung growth(GO:0060437) |
| 1.0 | 7.9 | GO:0019695 | choline metabolic process(GO:0019695) |
| 1.0 | 95.1 | GO:0006521 | regulation of cellular amino acid metabolic process(GO:0006521) |
| 0.9 | 2.8 | GO:0001923 | B-1 B cell differentiation(GO:0001923) |
| 0.9 | 36.5 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 0.9 | 3.7 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
| 0.9 | 3.6 | GO:1903436 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
| 0.9 | 16.9 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.9 | 19.3 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.9 | 5.3 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.9 | 8.7 | GO:0051005 | negative regulation of lipoprotein lipase activity(GO:0051005) |
| 0.8 | 9.8 | GO:0060576 | intestinal epithelial cell development(GO:0060576) |
| 0.8 | 18.8 | GO:0072663 | protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663) |
| 0.8 | 22.1 | GO:0003094 | glomerular filtration(GO:0003094) |
| 0.8 | 5.6 | GO:0007096 | regulation of exit from mitosis(GO:0007096) |
| 0.8 | 8.7 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.8 | 15.5 | GO:0006465 | signal peptide processing(GO:0006465) |
| 0.8 | 5.4 | GO:0048511 | rhythmic process(GO:0048511) |
| 0.8 | 6.1 | GO:0010624 | regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) |
| 0.8 | 6.8 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.7 | 6.4 | GO:0070900 | mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864) |
| 0.7 | 2.1 | GO:1904578 | response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) response to hypobaric hypoxia(GO:1990910) |
| 0.7 | 2.1 | GO:0051919 | positive regulation of fibrinolysis(GO:0051919) |
| 0.7 | 25.9 | GO:0006370 | 7-methylguanosine mRNA capping(GO:0006370) |
| 0.7 | 3.5 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.7 | 50.0 | GO:0070125 | mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126) |
| 0.7 | 29.4 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.7 | 10.9 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.7 | 6.1 | GO:0035092 | sperm chromatin condensation(GO:0035092) |
| 0.7 | 4.0 | GO:1903435 | positive regulation of constitutive secretory pathway(GO:1903435) |
| 0.7 | 5.3 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.6 | 2.5 | GO:0031339 | negative regulation of vesicle fusion(GO:0031339) |
| 0.6 | 12.6 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.6 | 12.9 | GO:2000052 | positive regulation of non-canonical Wnt signaling pathway(GO:2000052) |
| 0.6 | 9.2 | GO:0008635 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635) |
| 0.6 | 21.6 | GO:0031572 | G2 DNA damage checkpoint(GO:0031572) |
| 0.6 | 21.8 | GO:1902475 | neutral amino acid transport(GO:0015804) L-alpha-amino acid transmembrane transport(GO:1902475) |
| 0.6 | 1.1 | GO:0002036 | regulation of L-glutamate transport(GO:0002036) |
| 0.5 | 8.1 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 0.5 | 4.2 | GO:0045602 | negative regulation of endothelial cell differentiation(GO:0045602) |
| 0.5 | 14.3 | GO:0051131 | chaperone-mediated protein complex assembly(GO:0051131) |
| 0.5 | 13.3 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 0.5 | 4.9 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 0.5 | 1.9 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
| 0.5 | 26.8 | GO:0043392 | negative regulation of DNA binding(GO:0043392) |
| 0.5 | 2.7 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
| 0.4 | 0.9 | GO:1903336 | negative regulation of vacuolar transport(GO:1903336) |
| 0.4 | 2.2 | GO:0006581 | acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581) |
| 0.4 | 1.8 | GO:0046725 | negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697) |
| 0.4 | 5.2 | GO:0006228 | UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051) |
| 0.4 | 1.7 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
| 0.4 | 6.3 | GO:0042100 | B cell proliferation(GO:0042100) |
| 0.4 | 2.9 | GO:0008218 | bioluminescence(GO:0008218) |
| 0.4 | 1.2 | GO:0070233 | regulation of T cell apoptotic process(GO:0070232) negative regulation of T cell apoptotic process(GO:0070233) regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.4 | 4.1 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 0.4 | 25.5 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.4 | 1.9 | GO:0046391 | 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391) |
| 0.4 | 6.2 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.4 | 12.5 | GO:0002026 | regulation of the force of heart contraction(GO:0002026) |
| 0.4 | 4.1 | GO:0030656 | regulation of vitamin metabolic process(GO:0030656) |
| 0.4 | 2.6 | GO:0031087 | deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 0.4 | 2.6 | GO:0048318 | axial mesoderm development(GO:0048318) |
| 0.4 | 3.7 | GO:0015781 | pyrimidine nucleotide-sugar transport(GO:0015781) |
| 0.4 | 5.1 | GO:0006293 | nucleotide-excision repair, preincision complex stabilization(GO:0006293) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295) |
| 0.4 | 16.5 | GO:0042149 | cellular response to glucose starvation(GO:0042149) |
| 0.4 | 1.4 | GO:0090206 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
| 0.3 | 4.4 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 0.3 | 6.2 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.3 | 12.2 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
| 0.3 | 1.6 | GO:1901906 | diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
| 0.3 | 20.2 | GO:0001895 | retina homeostasis(GO:0001895) |
| 0.3 | 1.1 | GO:0010454 | negative regulation of cell fate commitment(GO:0010454) mammary gland bud morphogenesis(GO:0060648) regulation of determination of dorsal identity(GO:2000015) |
| 0.3 | 10.6 | GO:0015949 | nucleobase-containing small molecule interconversion(GO:0015949) |
| 0.3 | 8.1 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
| 0.3 | 16.2 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.2 | 15.9 | GO:0051225 | spindle assembly(GO:0051225) |
| 0.2 | 10.0 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.2 | 4.2 | GO:0060716 | labyrinthine layer blood vessel development(GO:0060716) |
| 0.2 | 14.1 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
| 0.2 | 14.1 | GO:1901222 | regulation of NIK/NF-kappaB signaling(GO:1901222) |
| 0.2 | 3.5 | GO:0006309 | apoptotic DNA fragmentation(GO:0006309) |
| 0.2 | 11.5 | GO:0045540 | regulation of cholesterol biosynthetic process(GO:0045540) |
| 0.2 | 9.6 | GO:0006378 | mRNA polyadenylation(GO:0006378) |
| 0.2 | 3.6 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.2 | 9.4 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.2 | 7.8 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
| 0.2 | 5.7 | GO:0016071 | mRNA metabolic process(GO:0016071) |
| 0.2 | 5.3 | GO:0006298 | mismatch repair(GO:0006298) |
| 0.2 | 0.9 | GO:0002002 | regulation of angiotensin levels in blood(GO:0002002) angiotensin maturation(GO:0002003) regulation of angiotensin metabolic process(GO:0060177) |
| 0.2 | 4.8 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
| 0.1 | 2.4 | GO:0007080 | mitotic metaphase plate congression(GO:0007080) |
| 0.1 | 1.0 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.1 | 2.2 | GO:0034067 | protein localization to Golgi apparatus(GO:0034067) |
| 0.1 | 1.9 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.1 | 2.8 | GO:0010801 | negative regulation of peptidyl-threonine phosphorylation(GO:0010801) |
| 0.1 | 0.9 | GO:0097084 | vascular smooth muscle cell development(GO:0097084) |
| 0.1 | 9.7 | GO:0035722 | interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349) |
| 0.1 | 1.3 | GO:0017145 | stem cell division(GO:0017145) |
| 0.1 | 2.6 | GO:0016486 | peptide hormone processing(GO:0016486) |
| 0.1 | 8.3 | GO:0070373 | negative regulation of ERK1 and ERK2 cascade(GO:0070373) |
| 0.1 | 2.3 | GO:0045577 | regulation of B cell differentiation(GO:0045577) |
| 0.1 | 11.0 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.1 | 4.2 | GO:0035987 | endodermal cell differentiation(GO:0035987) |
| 0.1 | 3.2 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.1 | 1.5 | GO:0046628 | positive regulation of insulin receptor signaling pathway(GO:0046628) |
| 0.1 | 3.2 | GO:0006333 | chromatin assembly or disassembly(GO:0006333) |
| 0.1 | 1.8 | GO:0006144 | purine nucleobase metabolic process(GO:0006144) |
| 0.1 | 0.7 | GO:0007566 | embryo implantation(GO:0007566) |
| 0.1 | 0.6 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
| 0.1 | 0.6 | GO:0045905 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.1 | 1.4 | GO:0001502 | cartilage condensation(GO:0001502) |
| 0.1 | 8.6 | GO:0033209 | tumor necrosis factor-mediated signaling pathway(GO:0033209) |
| 0.1 | 3.9 | GO:0048024 | regulation of mRNA splicing, via spliceosome(GO:0048024) |
| 0.1 | 3.0 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.1 | 1.1 | GO:0030502 | negative regulation of bone mineralization(GO:0030502) |
| 0.1 | 8.3 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 0.1 | 0.3 | GO:0032897 | negative regulation of viral transcription(GO:0032897) |
| 0.0 | 1.4 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.0 | 2.1 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
| 0.0 | 7.6 | GO:0070585 | protein localization to mitochondrion(GO:0070585) |
| 0.0 | 1.0 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.0 | 2.5 | GO:0006446 | regulation of translational initiation(GO:0006446) |
| 0.0 | 0.5 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.0 | 0.6 | GO:0006695 | cholesterol biosynthetic process(GO:0006695) |
| 0.0 | 0.5 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.0 | 0.9 | GO:1904837 | beta-catenin-TCF complex assembly(GO:1904837) |
| 0.0 | 0.7 | GO:0006491 | N-glycan processing(GO:0006491) |
| 0.0 | 0.3 | GO:0010745 | negative regulation of macrophage derived foam cell differentiation(GO:0010745) |
| 0.0 | 0.1 | GO:0035801 | adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802) visceral serous pericardium development(GO:0061032) posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) |
| 0.0 | 0.6 | GO:0007050 | cell cycle arrest(GO:0007050) |
| 0.0 | 0.4 | GO:0051353 | positive regulation of oxidoreductase activity(GO:0051353) |
| 0.0 | 2.2 | GO:0002576 | platelet degranulation(GO:0002576) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 19.1 | 76.4 | GO:0032301 | MutSalpha complex(GO:0032301) |
| 14.8 | 44.5 | GO:0009330 | DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330) |
| 9.2 | 73.5 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 8.1 | 32.4 | GO:0036502 | Derlin-1-VIMP complex(GO:0036502) |
| 7.4 | 66.2 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 6.9 | 69.4 | GO:0070938 | contractile ring(GO:0070938) |
| 6.5 | 65.3 | GO:0097255 | R2TP complex(GO:0097255) |
| 5.9 | 82.2 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 4.1 | 124.2 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 3.8 | 15.3 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 3.7 | 33.3 | GO:0000125 | PCAF complex(GO:0000125) |
| 3.3 | 117.2 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 3.0 | 27.0 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 2.9 | 34.9 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 2.7 | 21.6 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 2.7 | 10.7 | GO:0000799 | nuclear condensin complex(GO:0000799) |
| 2.6 | 71.1 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 2.4 | 40.6 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
| 2.3 | 13.9 | GO:0070545 | PeBoW complex(GO:0070545) |
| 2.3 | 13.8 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 2.2 | 15.5 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 2.2 | 10.9 | GO:0071986 | Ragulator complex(GO:0071986) |
| 2.1 | 12.5 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
| 2.0 | 6.0 | GO:0071020 | post-spliceosomal complex(GO:0071020) |
| 2.0 | 11.8 | GO:0000796 | condensin complex(GO:0000796) |
| 1.9 | 29.2 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 1.9 | 5.8 | GO:1903349 | omegasome membrane(GO:1903349) |
| 1.9 | 61.8 | GO:0005838 | proteasome regulatory particle(GO:0005838) |
| 1.9 | 11.5 | GO:1990037 | Lewy body core(GO:1990037) |
| 1.9 | 35.5 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 1.6 | 41.0 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 1.6 | 4.7 | GO:0031213 | RSF complex(GO:0031213) |
| 1.6 | 20.2 | GO:0097433 | dense body(GO:0097433) |
| 1.6 | 4.7 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 1.5 | 10.8 | GO:0070852 | cell body fiber(GO:0070852) |
| 1.5 | 7.4 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 1.5 | 33.7 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 1.4 | 25.9 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 1.4 | 15.8 | GO:0000243 | commitment complex(GO:0000243) |
| 1.4 | 70.0 | GO:0005876 | spindle microtubule(GO:0005876) |
| 1.4 | 10.8 | GO:0042382 | paraspeckles(GO:0042382) |
| 1.3 | 24.2 | GO:0036020 | endolysosome membrane(GO:0036020) |
| 1.3 | 75.5 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 1.2 | 8.3 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522) |
| 1.2 | 3.5 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 1.1 | 70.3 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 1.1 | 5.5 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 1.0 | 5.0 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 1.0 | 197.5 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 1.0 | 39.3 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.9 | 17.2 | GO:0031588 | cAMP-dependent protein kinase complex(GO:0005952) nucleotide-activated protein kinase complex(GO:0031588) |
| 0.9 | 41.2 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.8 | 21.4 | GO:0070822 | Sin3-type complex(GO:0070822) |
| 0.8 | 12.3 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.7 | 8.9 | GO:0045120 | pronucleus(GO:0045120) |
| 0.7 | 2.9 | GO:0097413 | Lewy body(GO:0097413) |
| 0.7 | 7.6 | GO:0045275 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.7 | 7.5 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.7 | 4.0 | GO:0071256 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 0.7 | 5.3 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 0.6 | 38.7 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.6 | 5.1 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.6 | 8.7 | GO:0008091 | spectrin(GO:0008091) |
| 0.6 | 8.6 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.6 | 13.0 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.6 | 2.8 | GO:0032449 | CBM complex(GO:0032449) |
| 0.6 | 23.9 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.5 | 6.8 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.5 | 3.8 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.5 | 25.5 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.5 | 4.2 | GO:0098645 | network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) |
| 0.4 | 7.5 | GO:0031932 | TORC2 complex(GO:0031932) TOR complex(GO:0038201) |
| 0.4 | 10.7 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.4 | 4.2 | GO:0070187 | telosome(GO:0070187) |
| 0.4 | 2.8 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.4 | 15.5 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.3 | 35.9 | GO:0000776 | kinetochore(GO:0000776) |
| 0.3 | 4.0 |