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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for MYOD1

Z-value: 1.01

Motif logo

Transcription factors associated with MYOD1

Gene Symbol Gene ID Gene Info
ENSG00000129152.3 myogenic differentiation 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MYOD1hg19_v2_chr11_+_17741111_177411240.243.3e-04Click!

Activity profile of MYOD1 motif

Sorted Z-values of MYOD1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_152590946 20.71 ENST00000172853.10
nebulin
chr11_+_1860200 16.75 ENST00000381911.1
troponin I type 2 (skeletal, fast)
chrX_-_107018969 16.45 ENST00000372383.4
TSC22 domain family, member 3
chr19_-_45826125 15.24 ENST00000221476.3
creatine kinase, muscle
chr16_+_30387141 14.70 ENST00000566955.1
myosin light chain, phosphorylatable, fast skeletal muscle
chr9_-_35689900 13.00 ENST00000378300.5
ENST00000329305.2
ENST00000360958.2
tropomyosin 2 (beta)
chr2_+_220283091 12.32 ENST00000373960.3
desmin
chr16_+_30383613 12.03 ENST00000568749.1
myosin light chain, phosphorylatable, fast skeletal muscle
chr11_+_1860682 11.72 ENST00000381906.1
troponin I type 2 (skeletal, fast)
chr11_+_1860832 11.29 ENST00000252898.7
troponin I type 2 (skeletal, fast)
chr5_+_66124590 10.98 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
microtubule associated serine/threonine kinase family member 4
chr16_+_30386098 10.52 ENST00000322861.7
myosin light chain, phosphorylatable, fast skeletal muscle
chr2_-_152590982 10.07 ENST00000409198.1
ENST00000397345.3
ENST00000427231.2
nebulin
chr22_-_36013368 9.52 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
myoglobin
chr3_-_52486841 9.41 ENST00000496590.1
troponin C type 1 (slow)
chr19_+_35739280 9.38 ENST00000602122.1
lipolysis stimulated lipoprotein receptor
chr19_+_35739782 9.35 ENST00000347609.4
lipolysis stimulated lipoprotein receptor
chr2_-_179672142 8.97 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
titin
chr3_+_52454971 8.96 ENST00000465863.1
PHD finger protein 7
chr9_-_35685452 8.91 ENST00000607559.1
tropomyosin 2 (beta)
chr19_+_35739597 8.88 ENST00000361790.3
lipolysis stimulated lipoprotein receptor
chr7_-_44105158 8.32 ENST00000297283.3
phosphoglycerate mutase 2 (muscle)
chr19_+_35739631 8.31 ENST00000602003.1
ENST00000360798.3
ENST00000354900.3
lipolysis stimulated lipoprotein receptor
chr20_-_44455976 8.13 ENST00000372555.3
troponin C type 2 (fast)
chr11_-_66725837 7.78 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
pyruvate carboxylase
chrX_-_107019181 7.26 ENST00000315660.4
ENST00000372384.2
ENST00000502650.1
ENST00000506724.1
TSC22 domain family, member 3
chr6_+_30852130 7.24 ENST00000428153.2
ENST00000376568.3
ENST00000452441.1
ENST00000515219.1
discoidin domain receptor tyrosine kinase 1
chr11_+_57365150 6.80 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr17_-_7165662 6.78 ENST00000571881.2
ENST00000360325.7
claudin 7
chr14_+_75746340 6.72 ENST00000555686.1
ENST00000555672.1
FBJ murine osteosarcoma viral oncogene homolog
chr2_+_170366203 6.65 ENST00000284669.1
kelch-like family member 41
chr22_-_36018569 6.63 ENST00000419229.1
ENST00000406324.1
myoglobin
chr14_+_75746781 6.53 ENST00000555347.1
FBJ murine osteosarcoma viral oncogene homolog
chr19_+_50936142 6.46 ENST00000357701.5
myosin binding protein C, fast type
chr1_-_16345245 6.07 ENST00000311890.9
heat shock 27kDa protein family, member 7 (cardiovascular)
chr21_+_27011584 5.95 ENST00000400532.1
ENST00000480456.1
ENST00000312957.5
junctional adhesion molecule 2
chrX_-_11445856 5.82 ENST00000380736.1
Rho GTPase activating protein 6
chr1_+_2005425 5.77 ENST00000461106.2
protein kinase C, zeta
chr11_+_1942580 5.66 ENST00000381558.1
troponin T type 3 (skeletal, fast)
chr10_-_103347883 5.57 ENST00000339310.3
ENST00000370158.3
ENST00000299206.4
ENST00000456836.2
ENST00000413344.1
ENST00000429502.1
ENST00000430045.1
ENST00000370172.1
ENST00000436284.2
ENST00000370162.3
polymerase (DNA directed), lambda
chr21_+_27011899 5.48 ENST00000425221.2
junctional adhesion molecule 2
chr11_-_117747607 5.43 ENST00000540359.1
ENST00000539526.1
FXYD domain containing ion transport regulator 6
chr12_-_6484715 5.41 ENST00000228916.2
sodium channel, non-voltage-gated 1 alpha subunit
chr6_+_30851840 5.39 ENST00000511510.1
ENST00000376569.3
ENST00000376575.3
ENST00000376570.4
ENST00000446312.1
ENST00000504927.1
discoidin domain receptor tyrosine kinase 1
chr11_-_117747434 5.35 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD domain containing ion transport regulator 6
chrX_-_133119476 5.34 ENST00000543339.1
glypican 3
chr15_-_45670924 5.31 ENST00000396659.3
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr19_+_35739897 5.30 ENST00000605618.1
ENST00000427250.1
ENST00000601623.1
lipolysis stimulated lipoprotein receptor
chr1_+_60280458 5.27 ENST00000455990.1
ENST00000371208.3
hook microtubule-tethering protein 1
chr11_-_111783595 5.25 ENST00000528628.1
crystallin, alpha B
chr4_-_40631859 5.22 ENST00000295971.7
ENST00000319592.4
RNA binding motif protein 47
chr18_+_77439775 5.12 ENST00000299543.7
ENST00000075430.7
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chrX_-_133119670 5.11 ENST00000394299.2
glypican 3
chr17_-_79269067 5.07 ENST00000288439.5
ENST00000374759.3
solute carrier family 38, member 10
chr3_-_50383096 5.05 ENST00000442887.1
ENST00000360165.3
zinc finger, MYND-type containing 10
chr4_-_186456766 4.97 ENST00000284771.6
PDZ and LIM domain 3
chr4_-_186456652 4.90 ENST00000284767.5
ENST00000284770.5
PDZ and LIM domain 3
chr19_-_18391708 4.80 ENST00000600972.1
jun D proto-oncogene
chr6_+_41021027 4.79 ENST00000244669.2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr11_-_2170786 4.71 ENST00000300632.5
insulin-like growth factor 2 (somatomedin A)
chr11_+_1940786 4.70 ENST00000278317.6
ENST00000381561.4
ENST00000381548.3
ENST00000360603.3
ENST00000381549.3
troponin T type 3 (skeletal, fast)
chr1_-_154164534 4.70 ENST00000271850.7
ENST00000368530.2
tropomyosin 3
chr15_+_74833518 4.65 ENST00000346246.5
AT rich interactive domain 3B (BRIGHT-like)
chr19_+_41103063 4.60 ENST00000308370.7
latent transforming growth factor beta binding protein 4
chr17_-_42277203 4.55 ENST00000587097.1
ataxin 7-like 3
chr22_+_22988816 4.41 ENST00000480559.1
ENST00000448514.1
gamma-glutamyltransferase light chain 2
chr11_-_117748138 4.40 ENST00000527717.1
FXYD domain containing ion transport regulator 6
chr10_+_102672712 4.19 ENST00000370271.3
ENST00000370269.3
ENST00000609386.1
family with sequence similarity 178, member A
chr9_+_6757634 4.13 ENST00000543771.1
ENST00000401787.3
ENST00000381306.3
ENST00000381309.3
lysine (K)-specific demethylase 4C
chr16_+_83932684 4.13 ENST00000262430.4
malonyl-CoA decarboxylase
chr1_-_150979333 4.07 ENST00000312210.5
family with sequence similarity 63, member A
chr3_-_46904918 4.05 ENST00000395869.1
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr17_+_36508111 4.04 ENST00000331159.5
ENST00000577233.1
suppressor of cytokine signaling 7
chr12_-_13248705 4.00 ENST00000396310.2
germ cell associated 1
chr3_+_47021168 3.98 ENST00000450053.3
ENST00000292309.5
ENST00000383740.2
neurobeachin-like 2
chr1_-_201391149 3.95 ENST00000555948.1
ENST00000556362.1
troponin I type 1 (skeletal, slow)
chr1_-_201081579 3.94 ENST00000367338.3
ENST00000362061.3
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr12_-_52967600 3.89 ENST00000549343.1
ENST00000305620.2
keratin 74
chr10_-_73848531 3.89 ENST00000373109.2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr19_+_35521572 3.88 ENST00000262631.5
sodium channel, voltage-gated, type I, beta subunit
chr3_-_46904946 3.82 ENST00000292327.4
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr22_-_20367797 3.80 ENST00000424787.2
gamma-glutamyltransferase light chain 3
chr19_+_3933579 3.79 ENST00000593949.1
nicotinamide riboside kinase 2
chr12_-_13248562 3.77 ENST00000457134.2
ENST00000537302.1
germ cell associated 1
chr9_-_131872928 3.77 ENST00000455830.2
ENST00000393384.3
ENST00000318080.2
carnitine O-acetyltransferase
chr6_+_30848557 3.76 ENST00000460944.2
ENST00000324771.8
discoidin domain receptor tyrosine kinase 1
chr19_+_18794470 3.73 ENST00000321949.8
ENST00000338797.6
CREB regulated transcription coactivator 1
chr22_-_50968419 3.71 ENST00000425169.1
ENST00000395680.1
ENST00000395681.1
ENST00000395678.3
ENST00000252029.3
thymidine phosphorylase
chr8_-_67341208 3.49 ENST00000499642.1
RP11-346I3.4
chr10_-_73848764 3.47 ENST00000317376.4
ENST00000412663.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr19_-_50316489 3.44 ENST00000533418.1
fuzzy planar cell polarity protein
chr12_-_13248732 3.43 ENST00000396302.3
germ cell associated 1
chr19_-_50316517 3.42 ENST00000313777.4
ENST00000445575.2
fuzzy planar cell polarity protein
chr11_-_119252359 3.36 ENST00000455332.2
ubiquitin specific peptidase 2
chr11_-_119252425 3.35 ENST00000260187.2
ubiquitin specific peptidase 2
chr3_-_57113314 3.34 ENST00000338458.4
ENST00000468727.1
Rho guanine nucleotide exchange factor (GEF) 3
chr18_+_47088401 3.33 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
lipase, endothelial
chr11_-_33891362 3.32 ENST00000395833.3
LIM domain only 2 (rhombotin-like 1)
chr11_-_76155618 3.30 ENST00000530759.1
RP11-111M22.3
chr1_-_154928562 3.29 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
pre-B-cell leukemia homeobox interacting protein 1
chr1_+_27561104 3.25 ENST00000361771.3
WD and tetratricopeptide repeats 1
chr10_+_123923205 3.24 ENST00000369004.3
ENST00000260733.3
transforming, acidic coiled-coil containing protein 2
chr20_+_49575342 3.24 ENST00000244051.1
molybdenum cofactor synthesis 3
chr7_-_73184588 3.23 ENST00000395145.2
claudin 3
chr10_-_124768300 3.19 ENST00000368886.5
IKAROS family zinc finger 5 (Pegasus)
chr5_-_1295104 3.09 ENST00000334602.6
ENST00000508104.2
ENST00000310581.5
ENST00000296820.5
telomerase reverse transcriptase
chr19_-_50316423 3.07 ENST00000528094.1
ENST00000526575.1
fuzzy planar cell polarity protein
chr11_-_66084508 3.04 ENST00000311330.3
CD248 molecule, endosialin
chr12_+_66582919 3.03 ENST00000545837.1
ENST00000457197.2
interleukin-1 receptor-associated kinase 3
chr16_-_46865047 2.99 ENST00000394806.2
chromosome 16 open reading frame 87
chr1_+_100315613 2.96 ENST00000361915.3
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr19_+_35521616 2.95 ENST00000595652.1
sodium channel, voltage-gated, type I, beta subunit
chr2_+_121103706 2.92 ENST00000295228.3
inhibin, beta B
chr15_-_35088340 2.92 ENST00000290378.4
actin, alpha, cardiac muscle 1
chr16_-_67427389 2.92 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
tubulin polymerization-promoting protein family member 3
chr10_+_123923105 2.91 ENST00000368999.1
transforming, acidic coiled-coil containing protein 2
chr2_-_24583583 2.91 ENST00000355123.4
intersectin 2
chr3_+_9975497 2.89 ENST00000397170.3
ENST00000383811.3
ENST00000452070.1
ENST00000326434.5
cysteine-rich with EGF-like domains 1
chr12_-_121342170 2.81 ENST00000353487.2
signal peptide peptidase like 3
chr12_+_50355647 2.79 ENST00000293599.6
aquaporin 5
chr17_-_47755338 2.78 ENST00000508805.1
ENST00000515508.2
ENST00000451526.2
ENST00000507970.1
speckle-type POZ protein
chr6_-_41703296 2.76 ENST00000373033.1
transcription factor EB
chr10_+_96162242 2.74 ENST00000225235.4
TBC1 domain family, member 12
chr15_-_48937884 2.70 ENST00000560355.1
fibrillin 1
chr6_-_137113604 2.69 ENST00000359015.4
mitogen-activated protein kinase kinase kinase 5
chr19_-_49658387 2.69 ENST00000595625.1
histidine rich calcium binding protein
chr3_+_32147997 2.69 ENST00000282541.5
glycerol-3-phosphate dehydrogenase 1-like
chr10_+_123922941 2.68 ENST00000360561.3
transforming, acidic coiled-coil containing protein 2
chr7_-_97881429 2.67 ENST00000420697.1
ENST00000379795.3
ENST00000415086.1
ENST00000542604.1
ENST00000447648.2
tectonin beta-propeller repeat containing 1
chr19_+_6135646 2.66 ENST00000588304.1
ENST00000588485.1
ENST00000588722.1
ENST00000591403.1
ENST00000586696.1
ENST00000589401.1
ENST00000252669.5
acyl-CoA synthetase bubblegum family member 2
chr1_-_85155939 2.65 ENST00000603677.1
synovial sarcoma, X breakpoint 2 interacting protein
chr17_+_76165213 2.61 ENST00000590201.1
synaptogyrin 2
chr5_-_150603679 2.60 ENST00000355417.2
coiled-coil domain containing 69
chr19_-_40791211 2.60 ENST00000579047.1
v-akt murine thymoma viral oncogene homolog 2
chr15_-_75660919 2.60 ENST00000569482.1
ENST00000565683.1
ENST00000561615.1
ENST00000563622.1
ENST00000568374.1
ENST00000566256.1
ENST00000267978.5
mannosidase, alpha, class 2C, member 1
chr5_-_159739532 2.57 ENST00000520748.1
ENST00000393977.3
ENST00000257536.7
cyclin J-like
chr2_+_48541776 2.56 ENST00000413569.1
ENST00000340553.3
forkhead box N2
chr14_+_105781102 2.56 ENST00000547217.1
phosphofurin acidic cluster sorting protein 2
chr16_-_31214051 2.48 ENST00000350605.4
PYD and CARD domain containing
chr7_+_73442422 2.46 ENST00000358929.4
ENST00000431562.1
ENST00000320492.7
ENST00000438906.1
elastin
chr11_-_64512273 2.43 ENST00000377497.3
ENST00000377487.1
ENST00000430645.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr2_-_220118631 2.41 ENST00000248437.4
tubulin, alpha 4a
chr16_+_58059470 2.41 ENST00000219271.3
matrix metallopeptidase 15 (membrane-inserted)
chr1_-_150669604 2.39 ENST00000427665.1
ENST00000540514.1
golgi phosphoprotein 3-like
chr19_+_19030478 2.37 ENST00000247003.4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr7_-_76829125 2.36 ENST00000248598.5
fibrinogen-like 2
chr2_-_183387430 2.35 ENST00000410103.1
phosphodiesterase 1A, calmodulin-dependent
chr8_-_145018080 2.34 ENST00000354589.3
plectin
chr6_-_136871957 2.34 ENST00000354570.3
microtubule-associated protein 7
chr20_-_50808236 2.33 ENST00000361387.2
ZFP64 zinc finger protein
chr8_-_134115118 2.32 ENST00000395352.3
ENST00000338087.5
Src-like-adaptor
chr10_-_62149433 2.29 ENST00000280772.2
ankyrin 3, node of Ranvier (ankyrin G)
chr17_-_80009650 2.26 ENST00000310496.4
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr5_+_56111361 2.26 ENST00000399503.3
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr19_+_19030497 2.19 ENST00000438170.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr17_-_53800217 2.18 ENST00000424486.2
transmembrane protein 100
chr10_+_104535994 2.17 ENST00000369889.4
WW domain binding protein 1-like
chr15_+_74466744 2.17 ENST00000560862.1
ENST00000395118.1
immunoglobulin superfamily containing leucine-rich repeat
chr15_-_75165651 2.17 ENST00000562363.1
ENST00000564529.1
ENST00000268099.9
secretory carrier membrane protein 2
chr3_+_5020801 2.16 ENST00000256495.3
basic helix-loop-helix family, member e40
chr15_-_48937982 2.15 ENST00000316623.5
fibrillin 1
chr1_-_150978953 2.14 ENST00000493834.2
family with sequence similarity 63, member A
chr12_-_48119301 2.14 ENST00000545824.2
ENST00000422538.3
endonuclease, polyU-specific
chr11_+_31531291 2.13 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
elongator acetyltransferase complex subunit 4
chr20_-_23967432 2.13 ENST00000286890.4
ENST00000278765.4
gamma-glutamyltransferase light chain 1
chr16_-_90038866 2.10 ENST00000314994.3
CENPB DNA-binding domains containing 1
chr11_-_86666427 2.09 ENST00000531380.1
frizzled family receptor 4
chr1_-_161168834 2.08 ENST00000367995.3
ENST00000367996.5
ADAM metallopeptidase with thrombospondin type 1 motif, 4
chr8_-_29120580 2.07 ENST00000524189.1
kinesin family member 13B
chr3_-_66024213 2.07 ENST00000483466.1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr19_+_3933085 2.06 ENST00000168977.2
ENST00000599576.1
nicotinamide riboside kinase 2
chr7_-_100171270 2.05 ENST00000538735.1
Sin3A-associated protein, 25kDa
chr2_+_233562015 2.05 ENST00000427233.1
ENST00000373566.3
ENST00000373563.4
ENST00000428883.1
ENST00000456491.1
ENST00000409480.1
ENST00000421433.1
ENST00000425040.1
ENST00000430720.1
ENST00000409547.1
ENST00000423659.1
ENST00000409196.3
ENST00000409451.3
ENST00000429187.1
ENST00000440945.1
GRB10 interacting GYF protein 2
chr12_-_48119340 2.05 ENST00000229003.3
endonuclease, polyU-specific
chr1_-_201346761 2.05 ENST00000455702.1
ENST00000422165.1
ENST00000367318.5
ENST00000367320.2
ENST00000438742.1
ENST00000412633.1
ENST00000458432.2
ENST00000421663.2
ENST00000367322.1
ENST00000509001.1
troponin T type 2 (cardiac)
chr1_+_28206150 2.04 ENST00000456990.1
thymocyte selection associated family member 2
chr2_+_24714729 2.02 ENST00000406961.1
ENST00000405141.1
nuclear receptor coactivator 1
chr19_+_7701985 2.00 ENST00000595950.1
ENST00000441779.2
ENST00000221283.5
ENST00000414284.2
syntaxin binding protein 2
chr12_-_42632016 1.99 ENST00000442791.3
ENST00000327791.4
ENST00000534854.2
ENST00000380788.3
ENST00000380790.4
YY1 associated factor 2
chr7_+_100210133 1.99 ENST00000393950.2
ENST00000424091.2
motile sperm domain containing 3
chr1_+_27561007 1.98 ENST00000319394.3
WD and tetratricopeptide repeats 1
chr5_+_150040403 1.97 ENST00000517768.1
ENST00000297130.4
myozenin 3
chr19_-_14228541 1.95 ENST00000590853.1
ENST00000308677.4
protein kinase, cAMP-dependent, catalytic, alpha
chr7_+_73442102 1.95 ENST00000445912.1
ENST00000252034.7
elastin
chr11_-_72145426 1.95 ENST00000535990.1
ENST00000437826.2
ENST00000340729.5
ClpB caseinolytic peptidase B homolog (E. coli)
chr6_-_45983581 1.94 ENST00000339561.6
chloride intracellular channel 5
chr1_-_115238207 1.94 ENST00000520113.2
ENST00000369538.3
ENST00000353928.6
adenosine monophosphate deaminase 1
chr19_+_41107249 1.92 ENST00000396819.3
latent transforming growth factor beta binding protein 4
chr3_+_50192499 1.91 ENST00000413852.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr4_+_128703295 1.91 ENST00000296464.4
ENST00000508549.1
heat shock 70kDa protein 4-like
chr4_-_82393009 1.91 ENST00000436139.2
RasGEF domain family, member 1B
chr19_-_49658641 1.91 ENST00000252825.4
histidine rich calcium binding protein
chr9_+_37650945 1.90 ENST00000377765.3
FERM and PDZ domain containing 1
chr7_+_73442457 1.88 ENST00000438880.1
ENST00000414324.1
ENST00000380562.4
elastin
chr17_-_44657017 1.87 ENST00000573185.1
ENST00000570550.1
ENST00000445552.2
ENST00000336125.5
ENST00000329240.4
ENST00000337845.7
ADP-ribosylation factor-like 17A
chr17_-_19648683 1.86 ENST00000573368.1
ENST00000457500.2
aldehyde dehydrogenase 3 family, member A1
chr17_+_34431212 1.86 ENST00000394495.1
chemokine (C-C motif) ligand 4
chr11_-_72145641 1.82 ENST00000538039.1
ENST00000445069.2
ClpB caseinolytic peptidase B homolog (E. coli)
chr12_+_56325812 1.82 ENST00000394147.1
ENST00000551156.1
ENST00000553783.1
ENST00000557080.1
ENST00000432422.3
ENST00000556001.1
diacylglycerol kinase, alpha 80kDa
chr20_+_57875658 1.81 ENST00000371025.3
endothelin 3

Network of associatons between targets according to the STRING database.

First level regulatory network of MYOD1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
8.2 41.2 GO:1904274 tricellular tight junction assembly(GO:1904274)
7.7 30.8 GO:0007525 somatic muscle development(GO:0007525)
3.0 9.0 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
3.0 23.7 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
2.9 11.5 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
2.6 10.5 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
2.6 7.8 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
2.5 9.9 GO:0090299 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
2.3 6.8 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
2.1 8.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
2.0 16.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
1.9 20.5 GO:0006600 creatine metabolic process(GO:0006600)
1.8 16.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
1.7 5.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
1.7 10.0 GO:0016554 cytidine to uridine editing(GO:0016554)
1.7 13.2 GO:0001661 conditioned taste aversion(GO:0001661)
1.6 4.9 GO:1900073 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
1.6 114.8 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
1.5 4.6 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
1.4 8.3 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
1.3 5.2 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
1.3 3.8 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
1.2 3.7 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
1.1 3.2 GO:0018307 enzyme active site formation(GO:0018307) tRNA thio-modification(GO:0034227)
1.0 3.1 GO:1900368 transcription, RNA-templated(GO:0001172) regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369) positive regulation of protein localization to nucleolus(GO:1904751)
1.0 2.9 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.9 4.7 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.9 5.6 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.9 3.5 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.8 3.3 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
0.8 4.1 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115) malonyl-CoA metabolic process(GO:2001293)
0.8 3.2 GO:0018032 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.7 10.5 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.7 2.9 GO:0003205 cardiac chamber development(GO:0003205)
0.7 2.8 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.7 2.0 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.6 3.0 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.6 4.7 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.6 2.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.6 1.7 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.6 2.3 GO:0072660 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.6 2.8 GO:0015670 carbon dioxide transport(GO:0015670)
0.5 2.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.5 4.1 GO:0070544 histone H3-K36 demethylation(GO:0070544) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.5 1.5 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294) negative regulation by host of viral genome replication(GO:0044828)
0.5 6.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.5 1.0 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.5 5.1 GO:0036159 inner dynein arm assembly(GO:0036159)
0.4 1.3 GO:0035283 rhombomere 3 development(GO:0021569) rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.4 3.6 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.4 1.3 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.4 1.8 GO:0036269 swimming behavior(GO:0036269)
0.4 3.5 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.4 2.6 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.4 1.3 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.4 6.7 GO:0045475 locomotor rhythm(GO:0045475)
0.4 1.7 GO:0021938 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.4 6.6 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.4 1.2 GO:1903413 cellular response to bile acid(GO:1903413)
0.4 1.2 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.4 2.8 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.4 1.6 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.4 2.4 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.4 1.6 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.4 3.9 GO:0071313 cellular response to caffeine(GO:0071313)
0.4 1.1 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.4 1.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.4 1.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.4 10.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.4 7.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 1.7 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.3 2.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.3 1.0 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.3 1.3 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.3 1.6 GO:2000035 regulation of stem cell division(GO:2000035)
0.3 2.6 GO:0006013 mannose metabolic process(GO:0006013)
0.3 5.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.3 1.6 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.3 2.2 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837) arterial endothelial cell differentiation(GO:0060842)
0.3 4.0 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.3 1.9 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.3 0.9 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.3 0.9 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.3 2.3 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.3 1.7 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.3 3.7 GO:0050808 synapse organization(GO:0050808)
0.3 6.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.3 1.4 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.3 2.7 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.3 2.4 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.3 1.6 GO:0018095 protein polyglutamylation(GO:0018095)
0.3 1.5 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.3 2.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.3 6.5 GO:0030252 growth hormone secretion(GO:0030252)
0.2 2.5 GO:0009414 response to water deprivation(GO:0009414)
0.2 1.2 GO:0061143 alveolar primary septum development(GO:0061143)
0.2 1.2 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.2 2.7 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.2 2.0 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.2 4.0 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.2 1.6 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.2 3.0 GO:0048535 lymph node development(GO:0048535)
0.2 1.6 GO:0019532 oxalate transport(GO:0019532)
0.2 3.7 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.2 0.5 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415) regulation of skeletal muscle tissue regeneration(GO:0043416)
0.2 2.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.2 3.1 GO:0035878 nail development(GO:0035878)
0.2 14.0 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.2 1.9 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.2 33.7 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.2 0.6 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.2 0.8 GO:0048496 maintenance of organ identity(GO:0048496)
0.2 0.6 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.2 0.6 GO:0061743 motor learning(GO:0061743)
0.2 2.0 GO:0007507 heart development(GO:0007507)
0.2 0.8 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2 1.6 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.2 3.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 1.1 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.2 0.6 GO:0060454 detection of temperature stimulus involved in thermoception(GO:0050960) positive regulation of gastric acid secretion(GO:0060454) response to capsazepine(GO:1901594)
0.2 0.7 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 7.1 GO:0055078 sodium ion homeostasis(GO:0055078)
0.2 0.7 GO:0015917 aminophospholipid transport(GO:0015917)
0.2 1.6 GO:0070997 neuron death(GO:0070997)
0.2 5.2 GO:0002076 osteoblast development(GO:0002076)
0.2 2.6 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.2 2.2 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.2 4.5 GO:0016578 histone deubiquitination(GO:0016578)
0.2 0.9 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.2 3.1 GO:0030220 platelet formation(GO:0030220)
0.2 2.6 GO:0051255 spindle midzone assembly(GO:0051255)
0.2 8.0 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 0.4 GO:0048936 sensory system development(GO:0048880) peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 1.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 0.7 GO:0003069 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1 0.9 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.3 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.1 0.9 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 1.0 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 1.0 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 4.1 GO:0005980 glycogen catabolic process(GO:0005980)
0.1 4.0 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.1 2.5 GO:1903392 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.1 2.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 2.0 GO:0050881 multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881)
0.1 1.0 GO:0006477 protein sulfation(GO:0006477)
0.1 6.9 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.1 2.7 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 1.2 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.1 2.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.9 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 2.1 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 1.0 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 1.0 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 4.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 2.0 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.9 GO:0032264 IMP salvage(GO:0032264)
0.1 0.7 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 1.7 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.4 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 1.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.9 GO:0000050 urea cycle(GO:0000050)
0.1 0.8 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 2.1 GO:0097352 autophagosome maturation(GO:0097352)
0.1 1.4 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.1 0.6 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 4.2 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 1.2 GO:0006853 carnitine shuttle(GO:0006853)
0.1 1.4 GO:0070977 bone maturation(GO:0070977)
0.1 1.6 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.1 0.9 GO:0007498 mesoderm development(GO:0007498)
0.1 1.7 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 8.8 GO:0021987 cerebral cortex development(GO:0021987)
0.1 1.1 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.9 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.1 3.5 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 1.2 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.1 0.4 GO:0006591 ornithine metabolic process(GO:0006591)
0.1 0.4 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1 0.7 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.1 0.7 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.1 1.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 1.0 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 0.8 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 2.7 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 0.5 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.8 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 2.0 GO:0043304 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.1 0.6 GO:0015074 DNA integration(GO:0015074)
0.1 1.8 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 1.1 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.1 0.6 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.1 2.3 GO:0051262 protein tetramerization(GO:0051262)
0.1 5.6 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 1.4 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 1.0 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.9 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.4 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 1.6 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 1.4 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.4 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.3 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.3 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 1.0 GO:0010863 positive regulation of phospholipase C activity(GO:0010863)
0.0 2.3 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 7.8 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.7 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 2.5 GO:0030449 regulation of complement activation(GO:0030449)
0.0 2.1 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 2.8 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.9 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 1.9 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 4.4 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.8 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.5 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 1.1 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 1.9 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.2 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.4 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 1.1 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.7 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.5 GO:0010543 regulation of platelet activation(GO:0010543)
0.0 3.9 GO:0006814 sodium ion transport(GO:0006814)
0.0 0.9 GO:0001525 angiogenesis(GO:0001525)
0.0 0.2 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.2 GO:0007517 muscle organ development(GO:0007517)
0.0 0.7 GO:0051058 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.0 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.4 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.4 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 1.6 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0 0.7 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 1.3 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.3 GO:0035967 cellular response to topologically incorrect protein(GO:0035967)
0.0 7.4 GO:0050900 leukocyte migration(GO:0050900)
0.0 0.5 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.5 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0035855 megakaryocyte development(GO:0035855)
0.0 1.5 GO:0070268 cornification(GO:0070268)
0.0 0.3 GO:0007159 leukocyte cell-cell adhesion(GO:0007159)
0.0 0.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.9 GO:0009798 axis specification(GO:0009798)
0.0 1.4 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.1 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.4 GO:0051693 actin filament capping(GO:0051693)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.6 GO:0006953 acute-phase response(GO:0006953)
0.0 2.4 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
6.9 41.2 GO:0061689 tricellular tight junction(GO:0061689)
3.1 73.7 GO:0005861 troponin complex(GO:0005861)
2.3 18.0 GO:0035976 AP1 complex(GO:0035976)
1.7 62.9 GO:0005859 muscle myosin complex(GO:0005859)
1.6 17.6 GO:0097512 cardiac myofibril(GO:0097512)
1.3 5.3 GO:0070695 FHF complex(GO:0070695)
1.2 21.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.8 7.9 GO:0071953 elastic fiber(GO:0071953)
0.8 3.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.7 5.8 GO:0045179 apical cortex(GO:0045179)
0.7 2.7 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.6 3.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.6 2.4 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.5 12.8 GO:0034706 sodium channel complex(GO:0034706)
0.4 4.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.4 2.5 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.4 2.0 GO:0042643 actomyosin, actin portion(GO:0042643)
0.4 1.2 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.4 4.9 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.4 2.8 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.4 4.0 GO:0097427 microtubule bundle(GO:0097427)
0.4 1.5 GO:0031417 NatC complex(GO:0031417)
0.4 6.6 GO:0031143 pseudopodium(GO:0031143)
0.3 10.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 4.6 GO:0000124 SAGA complex(GO:0000124)
0.3 3.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.3 2.0 GO:1990635 proximal dendrite(GO:1990635)
0.3 9.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.3 5.5 GO:0030056 hemidesmosome(GO:0030056)
0.3 7.2 GO:0034451 centriolar satellite(GO:0034451)
0.3 41.0 GO:0030018 Z disc(GO:0030018)
0.3 1.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 7.7 GO:0051233 spindle midzone(GO:0051233)
0.2 2.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.2 2.0 GO:0044194 cytolytic granule(GO:0044194)
0.2 4.2 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.2 1.0 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.2 2.2 GO:0033391 chromatoid body(GO:0033391)
0.2 2.4 GO:0005577 fibrinogen complex(GO:0005577)
0.2 1.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.2 1.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.2 0.7 GO:0044326 dendritic spine neck(GO:0044326)
0.2 1.4 GO:0070938 contractile ring(GO:0070938)
0.2 3.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 2.1 GO:0033270 paranode region of axon(GO:0033270)
0.1 8.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 2.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 3.0 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 6.1 GO:0016235 aggresome(GO:0016235)
0.1 2.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.1 1.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 11.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 1.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 3.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 2.8 GO:0009925 basal plasma membrane(GO:0009925)
0.1 2.0 GO:0034704 calcium channel complex(GO:0034704)
0.1 3.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.6 GO:1990769 proximal neuron projection(GO:1990769)
0.1 1.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 3.2 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 0.6 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 0.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.5 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.9 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 5.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 2.1 GO:0030057 desmosome(GO:0030057)
0.1 9.9 GO:0043204 perikaryon(GO:0043204)
0.1 1.8 GO:0030315 T-tubule(GO:0030315)
0.1 5.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 0.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 5.8 GO:0005884 actin filament(GO:0005884)
0.1 3.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 1.1 GO:0001726 ruffle(GO:0001726)
0.0 0.9 GO:0031968 mitochondrial outer membrane(GO:0005741) outer membrane(GO:0019867) organelle outer membrane(GO:0031968)
0.0 0.8 GO:0044295 axonal growth cone(GO:0044295)
0.0 3.5 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 2.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 2.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 1.7 GO:0097542 ciliary tip(GO:0097542)
0.0 2.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 1.2 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 3.2 GO:0055037 recycling endosome(GO:0055037)
0.0 0.8 GO:0016459 myosin complex(GO:0016459)
0.0 1.6 GO:0031526 brush border membrane(GO:0031526)
0.0 0.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 1.9 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 1.4 GO:0030427 growth cone(GO:0030426) site of polarized growth(GO:0030427)
0.0 3.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.4 GO:0031672 A band(GO:0031672)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 1.0 GO:0042629 mast cell granule(GO:0042629)
0.0 9.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.0 GO:0005768 endosome(GO:0005768)
0.0 1.2 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 0.1 GO:0005883 neurofilament(GO:0005883) neurofibrillary tangle(GO:0097418)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.4 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 2.7 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 2.7 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.5 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 2.2 GO:0005769 early endosome(GO:0005769)
0.0 0.5 GO:0035580 specific granule lumen(GO:0035580)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 49.2 GO:0031014 troponin T binding(GO:0031014)
3.3 16.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
2.9 25.9 GO:0043426 MRF binding(GO:0043426)
2.6 10.5 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
2.6 10.4 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
2.3 6.8 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
2.1 8.3 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
2.1 8.3 GO:0032038 myosin II heavy chain binding(GO:0032038)
1.9 15.2 GO:0004111 creatine kinase activity(GO:0004111)
1.5 5.8 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
1.2 16.2 GO:0005344 oxygen transporter activity(GO:0005344)
1.2 119.2 GO:0008307 structural constituent of muscle(GO:0008307)
1.0 3.1 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
1.0 5.1 GO:0008420 CTD phosphatase activity(GO:0008420)
1.0 2.0 GO:0030172 troponin C binding(GO:0030172)
1.0 2.0 GO:0030348 syntaxin-3 binding(GO:0030348)
0.9 3.7 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.8 2.5 GO:0032090 Pyrin domain binding(GO:0032090)
0.8 3.2 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.8 2.4 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.8 7.8 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.7 10.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.7 3.5 GO:0031708 endothelin B receptor binding(GO:0031708)
0.7 2.8 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.7 4.8 GO:0004126 cytidine deaminase activity(GO:0004126)
0.7 2.0 GO:0051373 FATZ binding(GO:0051373)
0.6 3.9 GO:1990254 keratin filament binding(GO:1990254)
0.6 4.9 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.6 2.4 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.6 5.6 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.5 3.2 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.5 4.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.5 8.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.5 4.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.5 7.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.5 3.8 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.4 0.4 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
0.4 1.3 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.4 3.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.4 1.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.4 1.2 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.4 1.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.4 1.9 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.4 8.4 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.4 19.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.3 3.7 GO:0004645 phosphorylase activity(GO:0004645)
0.3 2.3 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.3 3.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.3 1.6 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.3 1.6 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.3 0.9 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.3 16.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.3 6.1 GO:0031005 filamin binding(GO:0031005)
0.3 0.9 GO:0004962 endothelin receptor activity(GO:0004962)
0.3 4.6 GO:0045499 chemorepellent activity(GO:0045499)
0.3 7.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 5.8 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.3 1.6 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.3 3.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 1.9 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.3 1.6 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.3 4.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 1.7 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.2 1.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2 4.9 GO:0043495 protein anchor(GO:0043495)
0.2 6.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.2 3.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 0.7 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 5.3 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.2 5.3 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.2 0.6 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.2 1.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 3.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 1.0 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.2 0.8 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 2.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 5.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 2.8 GO:0015250 water channel activity(GO:0015250)
0.2 3.1 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.2 2.8 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 1.0 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.2 0.7 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.2 3.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 6.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 1.0 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 2.6 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 0.6 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.1 8.1 GO:0070063 RNA polymerase binding(GO:0070063)
0.1 1.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 2.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 1.3 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.1 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.9 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 3.0 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 2.0 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 1.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 2.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 1.0 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1 9.2 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 2.3 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 0.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 1.4 GO:0030955 potassium ion binding(GO:0030955)
0.1 2.0 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 2.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.3 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 8.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 4.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 1.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.4 GO:0017166 vinculin binding(GO:0017166)
0.1 1.3 GO:0051393 alpha-actinin binding(GO:0051393)
0.1 0.6 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 1.0 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 0.7 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.1 1.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 4.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.4 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 0.7 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 1.7 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 1.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.8 GO:0032027 myosin light chain binding(GO:0032027)
0.1 1.5 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 1.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 6.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 4.6 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 2.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 6.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.6 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 1.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.2 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 1.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 2.7 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 3.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 1.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.3 GO:0005109 frizzled binding(GO:0005109)
0.0 6.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.1 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.6 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 5.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.2 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 1.2 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 5.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 6.6 GO:0000287 magnesium ion binding(GO:0000287)
0.0 2.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 4.1 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 1.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.9 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 1.3 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 2.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.5 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.0 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.6 GO:0051087 chaperone binding(GO:0051087)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 5.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.0 GO:0051117 ATPase binding(GO:0051117)
0.0 0.9 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.9 GO:0019902 phosphatase binding(GO:0019902)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 17.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.3 1.6 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.2 17.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.2 4.6 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.2 2.6 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.2 5.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 4.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 2.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 7.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 4.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 7.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 9.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 3.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 20.5 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.1 1.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 2.2 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 3.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 1.6 ST GAQ PATHWAY G alpha q Pathway
0.1 4.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 15.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 1.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 6.0 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.1 1.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 15.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.0 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 2.2 PID AURORA A PATHWAY Aurora A signaling
0.1 1.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 3.9 PID AURORA B PATHWAY Aurora B signaling
0.1 3.7 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.2 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.8 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.8 PID ARF6 PATHWAY Arf6 signaling events
0.0 2.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.6 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.7 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.0 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.4 PID FGF PATHWAY FGF signaling pathway
0.0 2.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.6 PID P73PATHWAY p73 transcription factor network
0.0 1.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.9 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.1 PID LKB1 PATHWAY LKB1 signaling events
0.0 5.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.2 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.7 PID FOXO PATHWAY FoxO family signaling
0.0 0.8 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 143.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.7 14.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.4 10.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.4 1.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.3 6.8 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.3 6.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.3 2.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.3 9.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 18.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.3 10.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.3 3.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.2 2.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 5.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 2.9 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 2.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 3.0 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 3.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 5.1 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.1 6.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 2.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 4.1 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 3.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 3.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 4.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 3.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 2.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.0 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 2.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 4.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 9.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 2.3 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 1.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 0.6 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.6 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.8 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 2.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.9 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 2.3 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.4 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.2 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 1.4 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 5.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 2.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 2.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.0 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 1.6 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.0 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.0 0.3 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.6 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 1.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism