Project

GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

Navigation
Downloads

Results for NFE2L1

Z-value: 0.78

Motif logo

Transcription factors associated with NFE2L1

Gene Symbol Gene ID Gene Info
ENSG00000082641.11 nuclear factor, erythroid 2 like 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFE2L1hg19_v2_chr17_+_46125707_461257460.237.5e-04Click!

Activity profile of NFE2L1 motif

Sorted Z-values of NFE2L1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_35198243 12.02 ENST00000528455.1
CD44 molecule (Indian blood group)
chr11_+_35211511 11.16 ENST00000524922.1
CD44 molecule (Indian blood group)
chr11_+_35201826 10.42 ENST00000531873.1
CD44 molecule (Indian blood group)
chr11_+_35198118 10.38 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
CD44 molecule (Indian blood group)
chr2_-_106015527 10.04 ENST00000344213.4
ENST00000358129.4
four and a half LIM domains 2
chr16_-_69760409 9.33 ENST00000561500.1
ENST00000439109.2
ENST00000564043.1
ENST00000379046.2
ENST00000379047.3
NAD(P)H dehydrogenase, quinone 1
chr11_+_35211429 9.17 ENST00000525688.1
ENST00000278385.6
ENST00000533222.1
CD44 molecule (Indian blood group)
chr1_+_26605618 8.61 ENST00000270792.5
SH3 domain binding glutamic acid-rich protein like 3
chr18_+_657733 8.50 ENST00000323250.5
ENST00000323224.7
thymidylate synthetase
chr9_-_128246769 8.20 ENST00000444226.1
mitogen-activated protein kinase associated protein 1
chr7_+_872107 8.12 ENST00000405266.1
ENST00000401592.1
ENST00000403868.1
ENST00000425407.2
Sad1 and UNC84 domain containing 1
chr20_-_33539655 8.09 ENST00000451957.2
glutathione synthetase
chr1_-_24126023 7.95 ENST00000429356.1
UDP-galactose-4-epimerase
chr17_+_73230799 7.90 ENST00000579838.1
nucleoporin 85kDa
chr2_-_106015491 7.88 ENST00000408995.1
ENST00000393353.3
ENST00000322142.8
four and a half LIM domains 2
chr16_+_3068393 7.83 ENST00000573001.1
tumor necrosis factor receptor superfamily, member 12A
chr19_+_35645618 7.77 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD domain containing ion transport regulator 5
chr16_+_31044413 7.75 ENST00000394998.1
syntaxin 4
chr2_+_201994042 7.66 ENST00000417748.1
CASP8 and FADD-like apoptosis regulator
chr3_+_69928256 6.92 ENST00000394355.2
microphthalmia-associated transcription factor
chr6_-_43027105 6.70 ENST00000230413.5
ENST00000487429.1
ENST00000489623.1
ENST00000468957.1
mitochondrial ribosomal protein L2
chr5_+_68462944 6.69 ENST00000506572.1
cyclin B1
chr7_-_35077653 6.29 ENST00000310974.4
dpy-19-like 1 (C. elegans)
chr9_-_117853297 6.08 ENST00000542877.1
ENST00000537320.1
ENST00000341037.4
tenascin C
chr11_+_85339623 6.03 ENST00000358867.6
ENST00000534341.1
ENST00000393375.1
ENST00000531274.1
transmembrane protein 126B
chr6_+_63921399 5.95 ENST00000356170.3
FK506 binding protein 1C
chr3_-_81792780 5.91 ENST00000489715.1
glucan (1,4-alpha-), branching enzyme 1
chr2_+_201994208 5.90 ENST00000440180.1
CASP8 and FADD-like apoptosis regulator
chr22_+_38142235 5.81 ENST00000407319.2
ENST00000403663.2
ENST00000428075.1
TRIO and F-actin binding protein
chr18_+_55888767 5.78 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr1_-_222885770 5.74 ENST00000355727.2
ENST00000340020.6
axin interactor, dorsalization associated
chr3_-_149095652 5.63 ENST00000305366.3
transmembrane 4 L six family member 1
chr19_-_44160768 5.53 ENST00000593447.1
plasminogen activator, urokinase receptor
chr18_+_3252265 5.30 ENST00000580887.1
ENST00000536605.1
myosin, light chain 12A, regulatory, non-sarcomeric
chr11_-_107729887 5.26 ENST00000525815.1
solute carrier family 35, member F2
chr10_+_121410882 5.25 ENST00000369085.3
BCL2-associated athanogene 3
chr2_+_242289502 5.12 ENST00000451310.1
septin 2
chr16_-_58768177 4.88 ENST00000434819.2
ENST00000245206.5
glutamic-oxaloacetic transaminase 2, mitochondrial
chr5_+_159848854 4.76 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
pituitary tumor-transforming 1
chr1_-_115259337 4.53 ENST00000369535.4
neuroblastoma RAS viral (v-ras) oncogene homolog
chr2_-_64881018 4.49 ENST00000313349.3
SERTA domain containing 2
chr17_-_57784755 4.46 ENST00000537860.1
ENST00000393038.2
ENST00000409433.2
peptidyl-tRNA hydrolase 2
chrX_+_70503037 4.33 ENST00000535149.1
non-POU domain containing, octamer-binding
chr4_+_69962185 4.28 ENST00000305231.7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr11_+_101983176 4.25 ENST00000524575.1
Yes-associated protein 1
chr2_-_220119280 4.24 ENST00000392088.2
tubulin, alpha 4a
chr4_-_103749179 4.21 ENST00000502690.1
ubiquitin-conjugating enzyme E2D 3
chr17_+_57784997 4.17 ENST00000537567.1
ENST00000539763.1
ENST00000587945.1
ENST00000536180.1
ENST00000589823.2
ENST00000592106.1
ENST00000591315.1
ENST00000545362.1
vacuole membrane protein 1
chr6_+_63921351 4.15 ENST00000370659.1
FK506 binding protein 1C
chr5_+_33440802 4.13 ENST00000502553.1
ENST00000514259.1
ENST00000265112.3
threonyl-tRNA synthetase
chr17_+_73663470 4.09 ENST00000583536.1
SAP30 binding protein
chr9_-_36276966 4.07 ENST00000543356.2
ENST00000396594.3
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr15_+_89182178 4.06 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr2_+_234545092 4.06 ENST00000344644.5
UDP glucuronosyltransferase 1 family, polypeptide A10
chr12_+_20963632 4.05 ENST00000540853.1
ENST00000261196.2
solute carrier organic anion transporter family, member 1B3
chr17_+_57784826 4.04 ENST00000262291.4
vacuole membrane protein 1
chr11_+_12399071 4.04 ENST00000539723.1
ENST00000550549.1
parvin, alpha
chr15_+_80364901 4.00 ENST00000560228.1
ENST00000559835.1
ENST00000559775.1
ENST00000558688.1
ENST00000560392.1
ENST00000560976.1
ENST00000558272.1
ENST00000558390.1
zinc finger, AN1-type domain 6
chr4_-_103749205 3.97 ENST00000508249.1
ubiquitin-conjugating enzyme E2D 3
chr3_-_47934234 3.95 ENST00000420772.2
microtubule-associated protein 4
chr1_+_45478568 3.94 ENST00000428106.1
uroporphyrinogen decarboxylase
chr10_+_81272287 3.91 ENST00000520547.2
eukaryotic translation initiation factor 5A-like 1
chr10_+_94352956 3.78 ENST00000260731.3
kinesin family member 11
chr17_+_73663402 3.76 ENST00000355423.3
SAP30 binding protein
chr4_+_69962212 3.76 ENST00000508661.1
UDP glucuronosyltransferase 2 family, polypeptide B7
chr5_+_33441053 3.67 ENST00000541634.1
ENST00000455217.2
ENST00000414361.2
threonyl-tRNA synthetase
chr18_+_3252206 3.57 ENST00000578562.2
myosin, light chain 12A, regulatory, non-sarcomeric
chr2_+_234602305 3.53 ENST00000406651.1
UDP glucuronosyltransferase 1 family, polypeptide A6
chr17_-_40169429 3.53 ENST00000316603.7
ENST00000588641.1
DnaJ (Hsp40) homolog, subfamily C, member 7
chr16_+_31044812 3.50 ENST00000313843.3
syntaxin 4
chr2_+_219110149 3.49 ENST00000456575.1
actin related protein 2/3 complex, subunit 2, 34kDa
chr11_-_6640585 3.41 ENST00000533371.1
ENST00000528657.1
ENST00000436873.2
ENST00000299427.6
tripeptidyl peptidase I
chr1_+_32645269 3.41 ENST00000373610.3
taxilin alpha
chr12_-_112856623 3.36 ENST00000551291.2
ribosomal protein L6
chr14_+_64680854 3.36 ENST00000458046.2
spectrin repeat containing, nuclear envelope 2
chr11_+_59480899 3.31 ENST00000300150.7
syntaxin 3
chr12_+_123237321 3.29 ENST00000280557.6
ENST00000455982.2
density-regulated protein
chr15_+_89181974 3.27 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr6_+_160183492 3.23 ENST00000541436.1
acetyl-CoA acetyltransferase 2
chr11_+_71938925 3.20 ENST00000538751.1
inositol polyphosphate phosphatase-like 1
chr3_+_69812877 3.09 ENST00000457080.1
ENST00000328528.6
microphthalmia-associated transcription factor
chr11_+_65337901 3.05 ENST00000309328.3
ENST00000531405.1
ENST00000527920.1
ENST00000526877.1
ENST00000533115.1
ENST00000526433.1
Sjogren syndrome/scleroderma autoantigen 1
chr1_-_94312706 3.04 ENST00000370244.1
breast cancer anti-estrogen resistance 3
chr1_-_6445809 3.04 ENST00000377855.2
acyl-CoA thioesterase 7
chr13_+_48611665 3.01 ENST00000258662.2
nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr6_-_43595039 2.99 ENST00000307114.7
GTP binding protein 2
chr11_-_87908600 2.98 ENST00000531138.1
ENST00000526372.1
ENST00000243662.6
RAB38, member RAS oncogene family
chr17_+_76210267 2.98 ENST00000301633.4
ENST00000350051.3
ENST00000374948.2
ENST00000590449.1
baculoviral IAP repeat containing 5
chr9_+_37422663 2.96 ENST00000318158.6
ENST00000607784.1
glyoxylate reductase/hydroxypyruvate reductase
chr12_-_44200146 2.95 ENST00000395510.2
ENST00000325127.4
twinfilin actin-binding protein 1
chr14_+_102276209 2.95 ENST00000445439.3
ENST00000334743.5
ENST00000557095.1
protein phosphatase 2, regulatory subunit B', gamma
chr1_-_155211017 2.94 ENST00000536770.1
ENST00000368373.3
glucosidase, beta, acid
chr8_+_21823726 2.93 ENST00000433566.4
exportin 7
chr3_+_138340049 2.92 ENST00000464668.1
Fas apoptotic inhibitory molecule
chr12_-_106641728 2.87 ENST00000378026.4
cytoskeleton-associated protein 4
chr14_+_61447927 2.87 ENST00000451406.1
solute carrier family 38, member 6
chr9_+_5890802 2.85 ENST00000381477.3
ENST00000381476.1
ENST00000381471.1
melan-A
chrX_-_99891796 2.82 ENST00000373020.4
tetraspanin 6
chr12_-_65146636 2.78 ENST00000418919.2
glucosamine (N-acetyl)-6-sulfatase
chr6_+_32146131 2.76 ENST00000375094.3
ring finger protein 5, E3 ubiquitin protein ligase
chr9_+_70856899 2.75 ENST00000377342.5
ENST00000478048.1
COBW domain containing 3
chr2_+_234590556 2.73 ENST00000373426.3
UDP glucuronosyltransferase 1 family, polypeptide A7
chr6_-_3157760 2.67 ENST00000333628.3
tubulin, beta 2A class IIa
chr5_+_72143988 2.65 ENST00000506351.2
transportin 1
chr8_-_13372395 2.61 ENST00000276297.4
ENST00000511869.1
deleted in liver cancer 1
chr2_+_234545148 2.60 ENST00000373445.1
UDP glucuronosyltransferase 1 family, polypeptide A10
chr7_+_107220660 2.60 ENST00000465919.1
ENST00000445771.2
ENST00000479917.1
ENST00000421217.1
ENST00000457837.1
B-cell receptor-associated protein 29
chrX_+_11129388 2.59 ENST00000321143.4
ENST00000380763.3
ENST00000380762.4
holocytochrome c synthase
chr3_-_49142178 2.54 ENST00000452739.1
ENST00000414533.1
ENST00000417025.1
glutaminyl-tRNA synthetase
chr19_+_40477062 2.51 ENST00000455878.2
proteasome (prosome, macropain) 26S subunit, ATPase, 4
chr17_-_64216748 2.50 ENST00000585162.1
apolipoprotein H (beta-2-glycoprotein I)
chr4_-_103748696 2.50 ENST00000321805.7
ubiquitin-conjugating enzyme E2D 3
chr5_+_133707252 2.48 ENST00000506787.1
ENST00000507277.1
ubiquitin-conjugating enzyme E2B
chr5_+_65440032 2.47 ENST00000334121.6
splicing regulatory glutamine/lysine-rich protein 1
chr7_+_107220899 2.44 ENST00000379117.2
ENST00000473124.1
B-cell receptor-associated protein 29
chr3_-_47950745 2.44 ENST00000429422.1
microtubule-associated protein 4
chr6_+_30539153 2.41 ENST00000326195.8
ENST00000376545.3
ENST00000396515.4
ENST00000441867.1
ENST00000468958.1
ATP-binding cassette, sub-family F (GCN20), member 1
chr17_-_29233221 2.39 ENST00000580840.1
transcription elongation factor, mitochondrial
chrX_+_70503433 2.38 ENST00000276079.8
ENST00000373856.3
ENST00000373841.1
ENST00000420903.1
non-POU domain containing, octamer-binding
chr7_+_116312411 2.30 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
met proto-oncogene
chr11_+_7618413 2.30 ENST00000528883.1
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr7_-_148580563 2.30 ENST00000476773.1
enhancer of zeste homolog 2 (Drosophila)
chr22_+_38349670 2.30 ENST00000442738.2
ENST00000460648.1
ENST00000407936.1
ENST00000488684.1
ENST00000492213.1
ENST00000606538.1
ENST00000405557.1
polymerase (RNA) II (DNA directed) polypeptide F
chr1_+_95616933 2.29 ENST00000604203.1
TMEM56-RWDD3 readthrough
chr17_+_7155819 2.28 ENST00000570322.1
ENST00000576496.1
ENST00000574841.2
elongator acetyltransferase complex subunit 5
chr5_-_37371278 2.27 ENST00000231498.3
nucleoporin 155kDa
chr17_+_57274914 2.24 ENST00000582004.1
ENST00000577660.1
proline rich 11
Uncharacterized protein
chr22_-_32651326 2.23 ENST00000266086.4
solute carrier family 5 (glucose activated ion channel), member 4
chr5_+_162887556 2.21 ENST00000393915.4
ENST00000432118.2
ENST00000358715.3
hyaluronan-mediated motility receptor (RHAMM)
chr17_-_40169161 2.21 ENST00000589586.2
ENST00000426588.3
ENST00000589576.1
DnaJ (Hsp40) homolog, subfamily C, member 7
chr22_+_20861858 2.20 ENST00000414658.1
ENST00000432052.1
ENST00000425759.2
ENST00000292733.7
ENST00000542773.1
ENST00000263205.7
ENST00000406969.1
ENST00000382974.2
mediator complex subunit 15
chr2_+_234580525 2.20 ENST00000609637.1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr2_+_109237717 2.16 ENST00000409441.1
LIM and senescent cell antigen-like domains 1
chr14_+_64854958 2.11 ENST00000555709.2
ENST00000554739.1
ENST00000554768.1
ENST00000216605.8
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
chr15_+_89182156 2.11 ENST00000379224.5
interferon stimulated exonuclease gene 20kDa
chr2_-_113594279 2.10 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
interleukin 1, beta
chr6_-_144416737 2.09 ENST00000367569.2
splicing factor 3b, subunit 5, 10kDa
chrX_+_47077632 2.08 ENST00000457458.2
cyclin-dependent kinase 16
chr2_+_234580499 2.08 ENST00000354728.4
UDP glucuronosyltransferase 1 family, polypeptide A9
chr14_+_103801140 2.08 ENST00000561325.1
ENST00000392715.2
ENST00000559130.1
ENST00000559532.1
ENST00000558506.1
eukaryotic translation initiation factor 5
chr12_+_16035307 2.07 ENST00000538352.1
ENST00000025399.6
ENST00000419869.2
serine/threonine kinase receptor associated protein
chr7_-_142232071 2.07 ENST00000390364.3
T cell receptor beta variable 10-1(gene/pseudogene)
chr3_-_127541194 2.06 ENST00000453507.2
monoglyceride lipase
chr20_-_1447467 2.05 ENST00000353088.2
ENST00000350991.4
NSFL1 (p97) cofactor (p47)
chr2_+_169923577 2.05 ENST00000432060.2
dehydrogenase/reductase (SDR family) member 9
chr19_-_5719860 2.03 ENST00000590729.1
lon peptidase 1, mitochondrial
chr17_+_33914276 2.03 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
adaptor-related protein complex 2, beta 1 subunit
chr3_-_49142504 1.98 ENST00000306125.6
ENST00000420147.2
glutaminyl-tRNA synthetase
chr11_-_66103867 1.98 ENST00000424433.2
Ras and Rab interactor 1
chr4_+_169013666 1.96 ENST00000359299.3
annexin A10
chr4_+_113558272 1.95 ENST00000509061.1
ENST00000508577.1
ENST00000513553.1
La ribonucleoprotein domain family, member 7
chr14_+_22919081 1.94 ENST00000390473.1
T cell receptor delta joining 1
chr9_-_14180778 1.93 ENST00000380924.1
ENST00000543693.1
nuclear factor I/B
chr2_-_55496174 1.91 ENST00000417363.1
ENST00000412530.1
ENST00000394600.3
ENST00000366137.2
ENST00000420637.1
mitochondrial translational initiation factor 2
chr11_-_126138808 1.91 ENST00000332118.6
ENST00000532259.1
signal recognition particle receptor (docking protein)
chr7_-_22539771 1.90 ENST00000406890.2
ENST00000424363.1
STEAP family member 1B
chr1_-_214638146 1.89 ENST00000543945.1
protein tyrosine phosphatase, non-receptor type 14
chr7_-_41742697 1.86 ENST00000242208.4
inhibin, beta A
chr2_-_120980939 1.86 ENST00000426077.2
transmembrane protein 185B
chr1_+_45241186 1.84 ENST00000372209.3
ribosomal protein S8
chr9_-_130966497 1.84 ENST00000393608.1
ENST00000372948.3
CDKN1A interacting zinc finger protein 1
chr2_+_27651519 1.83 ENST00000379863.3
nuclear receptor binding protein 1
chr14_-_75530693 1.81 ENST00000555135.1
ENST00000357971.3
ENST00000553302.1
ENST00000555694.1
ENST00000238618.3
acylphosphatase 1, erythrocyte (common) type
chr16_-_4395905 1.81 ENST00000571941.1
presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr1_-_111506562 1.79 ENST00000485275.2
ENST00000369763.4
ligand dependent nuclear receptor interacting factor 1
chr7_+_107531580 1.78 ENST00000537148.1
ENST00000440410.1
ENST00000437604.2
dihydrolipoamide dehydrogenase
chr21_-_33975547 1.77 ENST00000431599.1
chromosome 21 open reading frame 59
chr2_+_234526272 1.77 ENST00000373450.4
UDP glucuronosyltransferase 1 family, polypeptide A8
chr6_-_131321863 1.76 ENST00000528282.1
erythrocyte membrane protein band 4.1-like 2
chr20_-_1447547 1.76 ENST00000476071.1
NSFL1 (p97) cofactor (p47)
chrX_-_41449204 1.72 ENST00000378179.3
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr12_+_28343353 1.71 ENST00000539107.1
coiled-coil domain containing 91
chr1_-_155211065 1.68 ENST00000427500.3
glucosidase, beta, acid
chr4_+_74606223 1.67 ENST00000307407.3
ENST00000401931.1
interleukin 8
chr12_+_51633061 1.64 ENST00000551313.1
DAZ associated protein 2
chr15_+_91478493 1.64 ENST00000418476.2
unc-45 homolog A (C. elegans)
chr19_+_9361606 1.63 ENST00000456448.1
olfactory receptor, family 7, subfamily E, member 24
chr12_-_102874102 1.61 ENST00000392905.2
insulin-like growth factor 1 (somatomedin C)
chr19_-_39881777 1.60 ENST00000595564.1
ENST00000221265.3
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr11_-_64052111 1.60 ENST00000394532.3
ENST00000394531.3
ENST00000309032.3
BCL2-associated agonist of cell death
chr2_+_228337079 1.58 ENST00000409315.1
ENST00000373671.3
ENST00000409171.1
ArfGAP with FG repeats 1
chr4_+_4861385 1.58 ENST00000382723.4
msh homeobox 1
chr19_+_40476912 1.58 ENST00000157812.2
proteasome (prosome, macropain) 26S subunit, ATPase, 4
chr10_+_115674530 1.58 ENST00000451472.1
CDNA FLJ20147 fis, clone COL07954; HCG1781466; Uncharacterized protein
chr10_+_5488564 1.57 ENST00000449083.1
ENST00000380359.3
neuroepithelial cell transforming 1
chr9_-_123676827 1.54 ENST00000546084.1
TNF receptor-associated factor 1
chr12_-_123752624 1.53 ENST00000542174.1
ENST00000535796.1
cyclin-dependent kinase 2 associated protein 1
chr5_+_138940742 1.53 ENST00000398733.3
ENST00000253815.2
ENST00000505007.1
ubiquitin-conjugating enzyme E2D 2
chr22_-_43040515 1.51 ENST00000361740.4
cytochrome b5 reductase 3
chr8_+_104831554 1.50 ENST00000408894.2
regulating synaptic membrane exocytosis 2
chr2_+_46769798 1.47 ENST00000238738.4
ras homolog family member Q
chr3_-_12705600 1.41 ENST00000542177.1
ENST00000442415.2
ENST00000251849.4
v-raf-1 murine leukemia viral oncogene homolog 1
chr8_+_9953061 1.40 ENST00000522907.1
ENST00000528246.1
methionine sulfoxide reductase A
chr14_+_22963806 1.39 ENST00000390493.1
T cell receptor alpha joining 44
chr6_+_27114861 1.38 ENST00000377459.1
histone cluster 1, H2ah
chr3_-_11685345 1.38 ENST00000430365.2
vestigial like 4 (Drosophila)
chr14_+_22739823 1.36 ENST00000390464.2
T cell receptor alpha variable 38-1
chr11_-_8680383 1.35 ENST00000299550.6
tripartite motif containing 66
chr17_+_39240459 1.34 ENST00000391417.4
keratin associated protein 4-7
chr1_+_43148059 1.30 ENST00000321358.7
ENST00000332220.6
Y box binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of NFE2L1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.6 53.2 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
3.7 11.2 GO:1902568 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
3.6 17.9 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
3.1 9.4 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
2.6 7.8 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
2.2 6.7 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
2.1 8.5 GO:0019860 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) transformation of host cell by virus(GO:0019087) uracil metabolic process(GO:0019860)
2.1 6.3 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
2.0 8.1 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
2.0 6.1 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
2.0 6.0 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
1.8 8.8 GO:0030047 actin modification(GO:0030047)
1.6 4.9 GO:0006106 fumarate metabolic process(GO:0006106) L-kynurenine metabolic process(GO:0097052)
1.5 15.4 GO:0051552 flavone metabolic process(GO:0051552)
1.5 4.5 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
1.4 5.5 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
1.4 8.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
1.4 13.6 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
1.2 6.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
1.2 4.6 GO:1901805 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
1.1 6.7 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
1.1 3.3 GO:0002188 translation reinitiation(GO:0002188)
1.1 6.4 GO:0051012 microtubule sliding(GO:0051012)
1.0 7.8 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.9 3.5 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.9 2.6 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.8 8.0 GO:0052695 cellular glucuronidation(GO:0052695)
0.8 2.3 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.8 3.0 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.8 3.0 GO:0006203 dGTP catabolic process(GO:0006203)
0.7 2.1 GO:0070487 monocyte aggregation(GO:0070487)
0.7 2.0 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.6 1.9 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.6 7.9 GO:0019388 galactose catabolic process(GO:0019388)
0.6 2.3 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.6 4.5 GO:0021815 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.5 2.7 GO:1904073 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.5 1.6 GO:0090427 activation of meiosis(GO:0090427)
0.5 3.6 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.5 2.0 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.5 5.0 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.5 3.9 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.5 4.3 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.5 2.3 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.5 1.8 GO:0044533 induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
0.4 1.8 GO:0009106 lipoate metabolic process(GO:0009106)
0.4 5.7 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.4 2.1 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.4 5.7 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.4 4.5 GO:2000210 positive regulation of anoikis(GO:2000210)
0.4 1.9 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.4 3.0 GO:0060155 platelet dense granule organization(GO:0060155)
0.4 8.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.4 1.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.4 1.8 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.4 0.4 GO:2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.3 1.0 GO:0060459 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung development(GO:0060459) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.3 1.9 GO:0032790 ribosome disassembly(GO:0032790)
0.3 4.1 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.3 1.5 GO:1990034 calcium ion export from cell(GO:1990034)
0.3 3.9 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.3 1.8 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.3 5.4 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.3 2.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.3 2.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.3 1.4 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.3 14.1 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.3 1.9 GO:2000795 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 4.0 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.3 0.8 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.3 2.4 GO:0006390 mitochondrial DNA replication(GO:0006264) transcription from mitochondrial promoter(GO:0006390)
0.3 1.1 GO:0032972 diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.3 5.2 GO:0010664 negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.3 1.8 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.3 15.1 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.3 2.3 GO:0016584 nucleosome positioning(GO:0016584)
0.3 1.0 GO:0048496 maintenance of organ identity(GO:0048496)
0.3 1.3 GO:0098502 DNA dephosphorylation(GO:0098502)
0.3 1.0 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.2 2.8 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.2 3.0 GO:0000278 mitotic cell cycle(GO:0000278)
0.2 10.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.2 1.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.2 1.4 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.2 1.6 GO:0001675 acrosome assembly(GO:0001675)
0.2 1.0 GO:0021759 globus pallidus development(GO:0021759)
0.2 9.3 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.2 2.3 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.2 2.6 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.2 1.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.2 1.1 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.2 3.3 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.2 2.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 7.7 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.2 0.5 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.2 2.8 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.2 8.2 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.2 3.5 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.2 0.8 GO:0034201 response to oleic acid(GO:0034201)
0.2 1.4 GO:0030091 protein repair(GO:0030091)
0.2 0.9 GO:0071105 response to interleukin-11(GO:0071105)
0.1 2.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.4 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 0.6 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 3.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 0.6 GO:1903672 positive regulation of sprouting angiogenesis(GO:1903672)
0.1 1.8 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.6 GO:0007097 nuclear migration(GO:0007097)
0.1 0.9 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 3.8 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 1.7 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 1.2 GO:0015846 polyamine transport(GO:0015846)
0.1 0.4 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.1 1.8 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 1.6 GO:0051451 myoblast migration(GO:0051451)
0.1 1.0 GO:0048733 sebaceous gland development(GO:0048733)
0.1 0.8 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 1.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 6.2 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 2.0 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.8 GO:0021903 rostrocaudal neural tube patterning(GO:0021903) positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1 2.6 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 8.8 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.1 0.2 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.1 1.9 GO:0001946 lymphangiogenesis(GO:0001946)
0.1 3.2 GO:0030252 growth hormone secretion(GO:0030252)
0.1 3.3 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.1 9.2 GO:0070527 platelet aggregation(GO:0070527)
0.1 0.7 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 1.7 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 10.1 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 0.9 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 2.6 GO:0017004 cytochrome complex assembly(GO:0017004)
0.1 0.6 GO:0070383 DNA cytosine deamination(GO:0070383)
0.1 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.1 0.6 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 1.6 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.1 6.0 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.5 GO:0009597 detection of virus(GO:0009597)
0.1 1.5 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.1 2.2 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 1.0 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 1.0 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.1 3.0 GO:0043171 peptide catabolic process(GO:0043171)
0.1 0.8 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 1.3 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.1 0.1 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 2.9 GO:0006611 protein export from nucleus(GO:0006611)
0.1 1.6 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.9 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 0.8 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.1 0.5 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 2.3 GO:2000816 negative regulation of mitotic sister chromatid separation(GO:2000816)
0.1 1.3 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 1.2 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.1 0.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 2.3 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.8 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 1.1 GO:0072663 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 1.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.5 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 2.1 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 1.2 GO:0001501 skeletal system development(GO:0001501)
0.0 1.0 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.5 GO:0055003 actin filament network formation(GO:0051639) cardiac myofibril assembly(GO:0055003)
0.0 0.9 GO:0043586 tongue development(GO:0043586)
0.0 0.4 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 3.2 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 2.8 GO:0007588 excretion(GO:0007588)
0.0 0.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 1.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.6 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 1.0 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.6 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 1.8 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 5.0 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 1.0 GO:0060135 response to progesterone(GO:0032570) maternal process involved in female pregnancy(GO:0060135)
0.0 0.4 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.7 GO:0014823 response to activity(GO:0014823)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.3 GO:0006768 biotin metabolic process(GO:0006768)
0.0 1.4 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.5 GO:0034453 microtubule anchoring(GO:0034453)
0.0 2.3 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.0 0.9 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.2 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.1 GO:0051058 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.8 GO:0051225 spindle assembly(GO:0051225)
0.0 1.9 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.5 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 1.0 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.0 0.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 2.1 GO:0030308 negative regulation of cell growth(GO:0030308)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
7.6 53.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
1.4 11.5 GO:0000322 storage vacuole(GO:0000322)
1.3 6.7 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
1.2 3.5 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
1.0 3.8 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.9 3.6 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.9 4.3 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.8 6.7 GO:0042382 paraspeckles(GO:0042382)
0.8 13.6 GO:0097342 ripoptosome(GO:0097342)
0.7 9.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.6 1.9 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.6 3.0 GO:0031905 early endosome lumen(GO:0031905)
0.6 1.8 GO:0043159 acrosomal matrix(GO:0043159)
0.6 2.3 GO:0044611 nuclear pore inner ring(GO:0044611)
0.6 1.7 GO:0097441 basilar dendrite(GO:0097441)
0.5 4.3 GO:0032133 chromosome passenger complex(GO:0032133)
0.5 2.6 GO:0033503 HULC complex(GO:0033503)
0.5 5.5 GO:0071438 invadopodium membrane(GO:0071438)
0.5 7.9 GO:0031080 nuclear pore outer ring(GO:0031080)
0.5 8.2 GO:0031932 TORC2 complex(GO:0031932)
0.5 1.8 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.4 2.7 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.3 17.9 GO:0031430 M band(GO:0031430)
0.3 1.0 GO:0002139 stereocilia coupling link(GO:0002139)
0.3 4.1 GO:0031595 nuclear proteasome complex(GO:0031595)
0.3 3.5 GO:0005614 interstitial matrix(GO:0005614)
0.3 4.1 GO:0097227 sperm annulus(GO:0097227)
0.3 2.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.3 2.8 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.2 2.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.2 8.5 GO:0000421 autophagosome membrane(GO:0000421)
0.2 4.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.2 0.6 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2 4.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 2.1 GO:0032797 SMN complex(GO:0032797)
0.2 1.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.2 2.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 6.7 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 2.3 GO:0045120 pronucleus(GO:0045120)
0.2 1.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.2 1.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 2.9 GO:0042599 lamellar body(GO:0042599)
0.1 2.8 GO:0036020 endolysosome membrane(GO:0036020)
0.1 1.0 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 2.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 2.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 1.5 GO:0005833 hemoglobin complex(GO:0005833)
0.1 6.2 GO:0005771 multivesicular body(GO:0005771)
0.1 1.7 GO:0005652 nuclear lamina(GO:0005652)
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.1 3.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.2 GO:0044327 dendritic spine head(GO:0044327)
0.1 2.1 GO:0005686 U2 snRNP(GO:0005686)
0.1 6.3 GO:0015030 Cajal body(GO:0015030)
0.1 6.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 5.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 7.8 GO:0016459 myosin complex(GO:0016459)
0.1 8.2 GO:0005643 nuclear pore(GO:0005643)
0.1 1.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.2 GO:0097452 GAIT complex(GO:0097452)
0.1 2.8 GO:0016592 mediator complex(GO:0016592)
0.1 1.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.5 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128)
0.1 10.3 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 2.3 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.2 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 10.0 GO:0030027 lamellipodium(GO:0030027)
0.1 3.4 GO:0072686 mitotic spindle(GO:0072686)
0.1 6.0 GO:0030175 filopodium(GO:0030175)
0.1 2.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 1.4 GO:0031143 pseudopodium(GO:0031143)
0.1 3.0 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 1.8 GO:0099738 cell cortex region(GO:0099738)
0.1 6.4 GO:0030018 Z disc(GO:0030018)
0.1 7.7 GO:0001726 ruffle(GO:0001726)
0.0 0.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.8 GO:0005922 connexon complex(GO:0005922)
0.0 1.0 GO:0030057 desmosome(GO:0030057)
0.0 9.8 GO:0005840 ribosome(GO:0005840)
0.0 5.8 GO:0030496 midbody(GO:0030496)
0.0 18.7 GO:0019866 mitochondrial inner membrane(GO:0005743) organelle inner membrane(GO:0019866)
0.0 4.3 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 3.6 GO:0000922 spindle pole(GO:0000922)
0.0 1.5 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 1.3 GO:0016235 aggresome(GO:0016235)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 2.8 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.4 GO:0000786 nucleosome(GO:0000786)
0.0 1.6 GO:0005741 mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968)
0.0 2.7 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.6 GO:0005811 lipid particle(GO:0005811)
0.0 2.5 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 11.5 GO:0005789 endoplasmic reticulum membrane(GO:0005789)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.4 GO:0008859 exoribonuclease II activity(GO:0008859)
2.8 11.2 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
2.6 7.9 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
2.6 7.8 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
1.8 5.5 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
1.8 54.9 GO:0005540 hyaluronic acid binding(GO:0005540)
1.6 4.9 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
1.5 4.5 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
1.5 4.5 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
1.5 2.9 GO:0003998 acylphosphatase activity(GO:0003998)
1.3 3.9 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
1.2 4.6 GO:0004348 glucosylceramidase activity(GO:0004348)
1.0 9.3 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
1.0 3.0 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) NADH pyrophosphatase activity(GO:0035529) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
1.0 6.7 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.8 3.2 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.8 6.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.7 3.0 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.7 27.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.7 2.1 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.7 2.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.7 2.0 GO:0070364 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.7 6.1 GO:0045545 syndecan binding(GO:0045545)
0.6 1.9 GO:0070699 type II activin receptor binding(GO:0070699)
0.6 8.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.6 1.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.6 8.5 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.6 2.4 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.6 8.1 GO:0016594 glycine binding(GO:0016594)
0.6 3.4 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.5 2.5 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.5 1.5 GO:0032427 GBD domain binding(GO:0032427)
0.5 5.8 GO:0045159 myosin II binding(GO:0045159)
0.5 1.9 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.5 4.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.4 13.6 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.4 5.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.4 3.0 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.4 2.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.4 8.1 GO:0043495 protein anchor(GO:0043495)
0.4 8.2 GO:0070300 phosphatidic acid binding(GO:0070300)
0.4 4.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.4 2.6 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.4 2.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.4 1.8 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.4 9.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.3 10.1 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.3 15.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.3 1.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.3 6.3 GO:0000030 mannosyltransferase activity(GO:0000030)
0.3 3.6 GO:0050544 icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.3 3.2 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.3 1.3 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) polynucleotide phosphatase activity(GO:0098518)
0.3 3.0 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.3 1.4 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.3 0.8 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.3 2.3 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.3 1.0 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2 2.8 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.2 0.7 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.2 1.8 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.2 16.1 GO:0050681 androgen receptor binding(GO:0050681)
0.2 1.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 2.2 GO:0031013 troponin I binding(GO:0031013)
0.2 1.8 GO:0042731 PH domain binding(GO:0042731)
0.2 6.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.2 7.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 2.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 5.7 GO:0001671 ATPase activator activity(GO:0001671)
0.2 2.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 4.3 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 3.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.5 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 1.9 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 2.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 7.4 GO:0070888 E-box binding(GO:0070888)
0.1 3.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.9 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.5 GO:0019862 IgA binding(GO:0019862)
0.1 0.2 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 0.9 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 2.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.8 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 2.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.5 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.9 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 1.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 2.0 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 3.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.3 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 1.4 GO:0019864 IgG binding(GO:0019864)
0.1 0.9 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 1.0 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.3 GO:0047708 biotinidase activity(GO:0047708)
0.1 3.3 GO:0043022 ribosome binding(GO:0043022)
0.1 2.9 GO:0003785 actin monomer binding(GO:0003785)
0.1 5.9 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 0.4 GO:0070404 NADH binding(GO:0070404)
0.1 1.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 1.8 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 2.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 2.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.5 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 1.0 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 0.2 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 1.4 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 2.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.6 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 2.6 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 3.8 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 2.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 10.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 8.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 1.0 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 2.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.5 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 1.6 GO:0050699 WW domain binding(GO:0050699)
0.0 6.3 GO:0016758 transferase activity, transferring hexosyl groups(GO:0016758)
0.0 2.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 8.4 GO:0001047 core promoter binding(GO:0001047)
0.0 1.9 GO:0002039 p53 binding(GO:0002039)
0.0 0.6 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 2.4 GO:0008135 translation factor activity, RNA binding(GO:0008135)
0.0 3.1 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.9 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.0 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 2.8 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.4 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 4.9 GO:0008017 microtubule binding(GO:0008017)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 7.3 GO:0045296 cadherin binding(GO:0045296)
0.0 2.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.0 GO:0017022 myosin binding(GO:0017022)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 1.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.6 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.3 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 54.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.6 20.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.5 13.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3 9.8 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.3 5.9 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.3 6.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.3 9.9 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.2 9.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 5.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.2 11.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.2 6.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 12.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 10.0 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 9.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 7.9 PID CDC42 PATHWAY CDC42 signaling events
0.1 4.0 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 1.9 PID ALK1 PATHWAY ALK1 signaling events
0.1 6.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 6.4 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 1.6 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 8.5 PID E2F PATHWAY E2F transcription factor network
0.1 1.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 1.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 2.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 2.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 1.3 PID ARF 3PATHWAY Arf1 pathway
0.0 1.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.0 PID INSULIN PATHWAY Insulin Pathway
0.0 1.0 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.9 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.9 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 2.2 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.2 PID ATM PATHWAY ATM pathway
0.0 0.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 54.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.8 20.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.5 5.9 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.5 7.0 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.5 13.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.4 11.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.4 8.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.3 12.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.3 12.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.3 7.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.3 9.9 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.2 6.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 9.8 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.2 15.5 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.2 4.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.2 3.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 4.9 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 6.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 5.5 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.2 4.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.2 2.7 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.2 2.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.2 3.6 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 2.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 5.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.9 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 4.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.0 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 1.7 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 9.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.8 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.1 13.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 1.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 1.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.0 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 2.0 REACTOME KINESINS Genes involved in Kinesins
0.1 2.2 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.1 1.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 5.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 2.1 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 2.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 2.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 4.8 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 2.1 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.9 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 5.1 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 1.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.4 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 2.1 REACTOME TRANSLATION Genes involved in Translation
0.0 0.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.9 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.0 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 2.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis