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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for NFKB2

Z-value: 1.11

Motif logo

Transcription factors associated with NFKB2

Gene Symbol Gene ID Gene Info
ENSG00000077150.13 nuclear factor kappa B subunit 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFKB2hg19_v2_chr10_+_104155450_1041554790.537.4e-17Click!

Activity profile of NFKB2 motif

Sorted Z-values of NFKB2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_37640277 28.30 ENST00000401529.3
ENST00000249071.6
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr1_-_27961720 24.30 ENST00000545953.1
ENST00000374005.3
feline Gardner-Rasheed sarcoma viral oncogene homolog
chr6_+_32605195 21.69 ENST00000374949.2
major histocompatibility complex, class II, DQ alpha 1
chr14_+_24605389 20.54 ENST00000382708.3
ENST00000561435.1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr22_-_37640456 19.73 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr14_-_24615805 17.47 ENST00000560410.1
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr19_-_41859814 17.45 ENST00000221930.5
transforming growth factor, beta 1
chr19_-_10450328 17.39 ENST00000160262.5
intercellular adhesion molecule 3
chr14_+_24605361 16.46 ENST00000206451.6
ENST00000559123.1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr19_+_48824711 16.29 ENST00000599704.1
epithelial membrane protein 3
chr17_-_34207295 15.96 ENST00000463941.1
ENST00000293272.3
chemokine (C-C motif) ligand 5
chr6_-_31324943 15.68 ENST00000412585.2
ENST00000434333.1
major histocompatibility complex, class I, B
chr11_+_34460447 15.09 ENST00000241052.4
catalase
chr6_+_32605134 15.02 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
major histocompatibility complex, class II, DQ alpha 1
chr2_-_89292422 13.50 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr14_-_24616426 13.13 ENST00000216802.5
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr2_-_89417335 12.88 ENST00000490686.1
immunoglobulin kappa variable 1-17
chrX_+_64887512 12.67 ENST00000360270.5
moesin
chr17_+_76164639 12.36 ENST00000225777.3
ENST00000585591.1
ENST00000589711.1
ENST00000588282.1
ENST00000589168.1
synaptogyrin 2
chr11_+_66247880 11.97 ENST00000360510.2
ENST00000453114.1
ENST00000541961.1
ENST00000532019.1
ENST00000526515.1
ENST00000530165.1
ENST00000533725.1
dipeptidyl-peptidase 3
chr17_+_76165213 11.96 ENST00000590201.1
synaptogyrin 2
chr5_-_150466692 11.90 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNFAIP3 interacting protein 1
chr19_+_42381173 11.79 ENST00000221972.3
CD79a molecule, immunoglobulin-associated alpha
chr1_-_183559693 11.09 ENST00000367535.3
ENST00000413720.1
ENST00000418089.1
neutrophil cytosolic factor 2
chr6_+_106959718 10.74 ENST00000369066.3
absent in melanoma 1
chr12_+_7055631 10.69 ENST00000543115.1
ENST00000399448.1
protein tyrosine phosphatase, non-receptor type 6
chr16_+_50776021 10.48 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
cylindromatosis (turban tumor syndrome)
chr17_+_16318909 10.46 ENST00000577397.1
transient receptor potential cation channel, subfamily V, member 2
chr19_-_6415695 10.40 ENST00000594496.1
ENST00000594745.1
ENST00000600480.1
KH-type splicing regulatory protein
chr11_-_104840093 10.36 ENST00000417440.2
ENST00000444739.2
caspase 4, apoptosis-related cysteine peptidase
chrX_+_49028265 10.35 ENST00000376322.3
ENST00000376327.5
proteolipid protein 2 (colonic epithelium-enriched)
chr11_-_57335750 10.30 ENST00000340573.4
ubiquitin-conjugating enzyme E2L 6
chr10_+_89622870 10.25 ENST00000371953.3
phosphatase and tensin homolog
chr1_-_183560011 10.13 ENST00000367536.1
neutrophil cytosolic factor 2
chr2_-_89340242 10.00 ENST00000480492.1
immunoglobulin kappa variable 1-12
chr17_+_72462525 9.94 ENST00000360141.3
CD300a molecule
chr17_+_16318850 9.88 ENST00000338560.7
transient receptor potential cation channel, subfamily V, member 2
chr1_-_183604794 9.82 ENST00000367534.1
ENST00000359856.6
ENST00000294742.6
actin related protein 2/3 complex, subunit 5, 16kDa
chr9_+_100745615 9.57 ENST00000339399.4
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr16_-_88878305 9.51 ENST00000569616.1
ENST00000563655.1
ENST00000567713.1
ENST00000426324.2
ENST00000378364.3
adenine phosphoribosyltransferase
chr12_-_76477707 9.32 ENST00000551992.1
nucleosome assembly protein 1-like 1
chr16_+_81812863 9.20 ENST00000359376.3
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr2_-_89310012 9.10 ENST00000493819.1
immunoglobulin kappa variable 1-9
chr20_-_4795747 8.88 ENST00000379376.2
Ras association (RalGDS/AF-6) domain family member 2
chr12_+_56110374 8.64 ENST00000549424.1
Uncharacterized protein
chr11_+_66247478 8.63 ENST00000531863.1
ENST00000532677.1
dipeptidyl-peptidase 3
chr19_+_42381337 8.58 ENST00000597454.1
ENST00000444740.2
CD79a molecule, immunoglobulin-associated alpha
chr3_-_182698381 8.56 ENST00000292782.4
DCN1, defective in cullin neddylation 1, domain containing 1
chr17_+_72462766 8.37 ENST00000392625.3
ENST00000361933.3
ENST00000310828.5
CD300a molecule
chr10_-_125851961 8.26 ENST00000346248.5
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr17_+_40440481 8.06 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
signal transducer and activator of transcription 5A
chr3_+_53195136 8.02 ENST00000394729.2
ENST00000330452.3
protein kinase C, delta
chr1_+_42922173 7.82 ENST00000455780.1
ENST00000372560.3
ENST00000372561.3
ENST00000372556.3
phosphopantothenoylcysteine synthetase
chr11_+_58910201 7.78 ENST00000528737.1
family with sequence similarity 111, member A
chr19_-_39330818 7.69 ENST00000594769.1
ENST00000602021.1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial
chr1_+_207494853 7.52 ENST00000367064.3
ENST00000367063.2
ENST00000391921.4
ENST00000367067.4
ENST00000314754.8
ENST00000367065.5
ENST00000391920.4
ENST00000367062.4
ENST00000343420.6
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
chr16_+_4674814 7.40 ENST00000415496.1
ENST00000587747.1
ENST00000399577.5
ENST00000588994.1
ENST00000586183.1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr1_-_40042416 7.30 ENST00000372857.3
ENST00000372856.3
ENST00000531243.2
ENST00000451091.2
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr1_+_42921761 7.27 ENST00000372562.1
phosphopantothenoylcysteine synthetase
chr2_-_89568263 7.24 ENST00000473726.1
immunoglobulin kappa variable 1-33
chr8_+_90770008 7.20 ENST00000540020.1
receptor-interacting serine-threonine kinase 2
chr22_+_35796108 7.14 ENST00000382011.5
ENST00000416905.1
minichromosome maintenance complex component 5
chr2_+_219081817 7.05 ENST00000315717.5
ENST00000420104.1
ENST00000295685.10
actin related protein 2/3 complex, subunit 2, 34kDa
chr2_+_89952792 6.99 ENST00000390265.2
immunoglobulin kappa variable 1D-33
chr11_+_65405556 6.94 ENST00000534313.1
ENST00000533361.1
ENST00000526137.1
signal-induced proliferation-associated 1
chr10_-_36813162 6.92 ENST00000440465.1
nicotinamide phosphoribosyltransferase-like
chr1_-_33283754 6.86 ENST00000373477.4
tyrosyl-tRNA synthetase
chr3_+_23847432 6.59 ENST00000346855.3
ubiquitin-conjugating enzyme E2E 1
chr22_+_35796056 6.56 ENST00000216122.4
minichromosome maintenance complex component 5
chr1_+_226250379 6.49 ENST00000366815.3
ENST00000366814.3
H3 histone, family 3A
chr12_+_56110247 6.45 ENST00000551926.1
biogenesis of lysosomal organelles complex-1, subunit 1
chr2_-_89247338 6.45 ENST00000496168.1
immunoglobulin kappa variable 1-5
chrX_-_118986911 6.35 ENST00000276201.2
ENST00000345865.2
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr11_+_64949158 6.31 ENST00000527739.1
ENST00000526966.1
ENST00000533129.1
ENST00000524773.1
calpain 1, (mu/I) large subunit
chr6_-_32157947 6.22 ENST00000375050.4
pre-B-cell leukemia homeobox 2
chr1_-_150207017 6.16 ENST00000369119.3
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr16_-_15736881 6.12 ENST00000540441.2
KIAA0430
chr1_+_2487800 6.03 ENST00000355716.4
tumor necrosis factor receptor superfamily, member 14
chr16_-_28222797 5.98 ENST00000569951.1
ENST00000565698.1
exportin 6
chr3_+_23847394 5.98 ENST00000306627.3
ubiquitin-conjugating enzyme E2E 1
chr11_+_64949899 5.92 ENST00000531068.1
ENST00000527699.1
ENST00000533909.1
ENST00000527323.1
calpain 1, (mu/I) large subunit
chr16_-_15736953 5.88 ENST00000548025.1
ENST00000551742.1
ENST00000602337.1
ENST00000344181.3
ENST00000396368.3
KIAA0430
chr1_-_89458287 5.62 ENST00000370485.2
cysteine conjugate-beta lyase 2
chr8_+_22446763 5.61 ENST00000450780.2
ENST00000430850.2
ENST00000447849.1
Uncharacterized protein
chr10_+_104154229 5.53 ENST00000428099.1
ENST00000369966.3
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr8_+_22436248 5.49 ENST00000308354.7
PDZ and LIM domain 2 (mystique)
chr1_-_205744574 5.47 ENST00000367139.3
ENST00000235932.4
ENST00000437324.2
ENST00000414729.1
RAB7, member RAS oncogene family-like 1
chr8_+_22436635 5.36 ENST00000452226.1
ENST00000397760.4
ENST00000339162.7
ENST00000397761.2
PDZ and LIM domain 2 (mystique)
chr11_+_64949343 5.35 ENST00000279247.6
ENST00000532285.1
ENST00000534373.1
calpain 1, (mu/I) large subunit
chr12_+_69080734 5.28 ENST00000378905.2
nucleoporin 107kDa
chr6_+_135502408 5.28 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
v-myb avian myeloblastosis viral oncogene homolog
chr1_+_231376941 5.27 ENST00000436239.1
ENST00000366647.4
ENST00000366646.3
ENST00000416000.1
glyceronephosphate O-acyltransferase
chr14_+_97263641 5.26 ENST00000216639.3
vaccinia related kinase 1
chr11_+_58910295 5.21 ENST00000420244.1
family with sequence similarity 111, member A
chr19_-_1885432 5.17 ENST00000250974.9
abhydrolase domain containing 17A
chr11_+_66406088 5.11 ENST00000310092.7
ENST00000396053.4
ENST00000408993.2
RNA binding motif protein 4
chr8_+_145582231 5.10 ENST00000526338.1
ENST00000402965.1
ENST00000534725.1
ENST00000532887.1
ENST00000329994.2
solute carrier family 52 (riboflavin transporter), member 2
chr16_-_28223166 5.00 ENST00000304658.5
exportin 6
chr1_-_89458415 4.98 ENST00000321792.5
ENST00000370491.3
RNA binding motif protein, X-linked-like 1
cysteine conjugate-beta lyase 2
chr17_+_34900737 4.97 ENST00000304718.4
ENST00000485685.2
gametogenetin binding protein 2
chr9_+_134103496 4.96 ENST00000498010.1
ENST00000476004.1
ENST00000528406.1
nucleoporin 214kDa
chr1_-_155232047 4.86 ENST00000302631.3
secretory carrier membrane protein 3
chr17_-_5487277 4.81 ENST00000572272.1
ENST00000354411.3
ENST00000577119.1
NLR family, pyrin domain containing 1
chr10_+_22605374 4.71 ENST00000448361.1
COMM domain containing 3
chr20_-_48330377 4.70 ENST00000371711.4
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
chr2_-_197036289 4.68 ENST00000263955.4
serine/threonine kinase 17b
chr14_-_24615523 4.67 ENST00000559056.1
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr12_+_12870055 4.63 ENST00000228872.4
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr1_-_146082633 4.61 ENST00000605317.1
ENST00000604938.1
ENST00000339388.5
neuroblastoma breakpoint family, member 11
chr1_-_28559502 4.61 ENST00000263697.4
DnaJ (Hsp40) homolog, subfamily C, member 8
chr16_-_4465886 4.59 ENST00000539968.1
coronin 7
chr7_+_73588575 4.55 ENST00000265753.8
eukaryotic translation initiation factor 4H
chr11_+_6624955 4.54 ENST00000299421.4
ENST00000537806.1
integrin-linked kinase
chr6_-_17706618 4.53 ENST00000262077.2
ENST00000537253.1
nucleoporin 153kDa
chr4_-_860950 4.53 ENST00000511980.1
ENST00000510799.1
cyclin G associated kinase
chr1_-_47655686 4.51 ENST00000294338.2
PDZK1 interacting protein 1
chr17_+_7462103 4.43 ENST00000396545.4
tumor necrosis factor (ligand) superfamily, member 13
chr12_+_56109926 4.38 ENST00000547076.1
biogenesis of lysosomal organelles complex-1, subunit 1
chr11_-_3862206 4.36 ENST00000351018.4
ras homolog family member G
chr19_-_14628645 4.36 ENST00000598235.1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr19_-_1885511 4.36 ENST00000292577.7
abhydrolase domain containing 17A
chr11_+_6625046 4.31 ENST00000396751.2
integrin-linked kinase
chr8_+_145582217 4.11 ENST00000530047.1
ENST00000527078.1
solute carrier family 52 (riboflavin transporter), member 2
chr14_-_23058063 4.09 ENST00000538631.1
ENST00000543337.1
ENST00000250498.4
defender against cell death 1
chr16_+_15737124 4.02 ENST00000396355.1
ENST00000396353.2
nudE neurodevelopment protein 1
chr22_-_43411106 3.97 ENST00000453643.1
ENST00000263246.3
ENST00000337959.4
protein kinase C and casein kinase substrate in neurons 2
chr1_-_202129105 3.97 ENST00000367279.4
protein tyrosine phosphatase, non-receptor type 7
chr16_-_67281413 3.95 ENST00000258201.4
formin homology 2 domain containing 1
chrX_-_23761317 3.94 ENST00000492081.1
ENST00000379303.5
ENST00000336430.7
acyl-CoA thioesterase 9
chr2_-_16847084 3.88 ENST00000406434.1
ENST00000381323.3
family with sequence similarity 49, member A
chr17_-_3819751 3.86 ENST00000225538.3
purinergic receptor P2X, ligand-gated ion channel, 1
chr14_+_100705322 3.86 ENST00000262238.4
YY1 transcription factor
chr17_+_38497640 3.85 ENST00000394086.3
retinoic acid receptor, alpha
chr20_+_35807512 3.82 ENST00000373622.5
ribophorin II
chr15_+_85923797 3.80 ENST00000559362.1
A kinase (PRKA) anchor protein 13
chr8_+_86376081 3.78 ENST00000285379.5
carbonic anhydrase II
chr8_-_130951940 3.75 ENST00000522250.1
ENST00000522941.1
ENST00000522746.1
ENST00000520204.1
ENST00000519070.1
ENST00000520254.1
ENST00000519824.2
ENST00000519540.1
family with sequence similarity 49, member B
chr11_-_61560053 3.74 ENST00000537328.1
transmembrane protein 258
chr1_+_90287480 3.73 ENST00000394593.3
leucine rich repeat containing 8 family, member D
chr11_-_33891362 3.70 ENST00000395833.3
LIM domain only 2 (rhombotin-like 1)
chr2_+_61108650 3.68 ENST00000295025.8
v-rel avian reticuloendotheliosis viral oncogene homolog
chr15_+_77287426 3.68 ENST00000558012.1
ENST00000267939.5
ENST00000379595.3
proline-serine-threonine phosphatase interacting protein 1
chr5_+_73980965 3.61 ENST00000261416.7
hexosaminidase B (beta polypeptide)
chr6_+_14117872 3.61 ENST00000379153.3
CD83 molecule
chr10_+_22605304 3.59 ENST00000475460.2
ENST00000602390.1
ENST00000489125.2
ENST00000456711.1
ENST00000444869.1
COMMD3-BMI1 readthrough
COMM domain containing 3
chr12_+_56110315 3.57 ENST00000548556.1
biogenesis of lysosomal organelles complex-1, subunit 1
chr8_-_145641864 3.50 ENST00000276833.5
solute carrier family 39 (zinc transporter), member 4
chr1_+_52195480 3.48 ENST00000531828.1
ENST00000361556.5
ENST00000481937.1
oxysterol binding protein-like 9
chr11_+_706113 3.46 ENST00000318562.8
ENST00000533256.1
ENST00000534755.1
EPS8-like 2
chr16_-_4466622 3.43 ENST00000570645.1
ENST00000574025.1
ENST00000572898.1
ENST00000537233.2
ENST00000571059.1
ENST00000251166.4
coronin 7
chr3_+_107241783 3.40 ENST00000415149.2
ENST00000402543.1
ENST00000325805.8
ENST00000427402.1
bobby sox homolog (Drosophila)
chr16_+_50775971 3.40 ENST00000311559.9
ENST00000564326.1
ENST00000566206.1
cylindromatosis (turban tumor syndrome)
chr2_+_74153953 3.40 ENST00000264093.4
ENST00000348222.1
deoxyguanosine kinase
chr7_+_73588665 3.37 ENST00000353999.6
eukaryotic translation initiation factor 4H
chr9_+_130922537 3.34 ENST00000372994.1
chromosome 9 open reading frame 16
chrX_-_15872914 3.33 ENST00000380291.1
ENST00000545766.1
ENST00000421527.2
ENST00000329235.2
adaptor-related protein complex 1, sigma 2 subunit
chr19_+_22235310 3.33 ENST00000600162.1
zinc finger protein 257
chr17_+_21191341 3.33 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
mitogen-activated protein kinase kinase 3
chr15_+_85923856 3.31 ENST00000560302.1
ENST00000394518.2
ENST00000361243.2
ENST00000560256.1
A kinase (PRKA) anchor protein 13
chr2_-_197664366 3.31 ENST00000409364.3
ENST00000263956.3
general transcription factor IIIC, polypeptide 3, 102kDa
chr9_+_130911723 3.29 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
lipocalin 2
chr2_-_219157250 3.28 ENST00000434015.2
ENST00000444183.1
ENST00000420341.1
ENST00000453281.1
ENST00000258412.3
ENST00000440422.1
transmembrane BAX inhibitor motif containing 1
chr2_+_61108771 3.28 ENST00000394479.3
v-rel avian reticuloendotheliosis viral oncogene homolog
chr20_+_61584026 3.28 ENST00000370351.4
ENST00000370349.3
solute carrier family 17 (vesicular nucleotide transporter), member 9
chr17_-_56429500 3.25 ENST00000225504.3
suppressor of Ty 4 homolog 1 (S. cerevisiae)
chr17_-_79881408 3.25 ENST00000392366.3
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr8_+_26149007 3.20 ENST00000380737.3
ENST00000524169.1
protein phosphatase 2, regulatory subunit B, alpha
chr2_+_74154032 3.15 ENST00000356837.6
deoxyguanosine kinase
chr3_+_51705222 3.10 ENST00000457573.1
ENST00000341333.5
ENST00000412249.1
ENST00000425781.1
ENST00000415259.1
ENST00000395057.1
ENST00000416589.1
testis expressed 264
chr17_-_73178599 3.01 ENST00000578238.1
small ubiquitin-like modifier 2
chr1_+_24117627 3.00 ENST00000400061.1
lysophospholipase II
chr3_-_56717246 2.99 ENST00000355628.5
family with sequence similarity 208, member A
chr11_-_61560254 2.96 ENST00000543510.1
transmembrane protein 258
chr12_+_70637494 2.95 ENST00000548159.1
ENST00000549750.1
ENST00000551043.1
CCR4-NOT transcription complex, subunit 2
chr17_+_7123125 2.95 ENST00000356839.5
ENST00000583312.1
ENST00000350303.5
acyl-CoA dehydrogenase, very long chain
chr1_-_209824643 2.94 ENST00000391911.1
ENST00000415782.1
laminin, beta 3
chr10_+_112257596 2.91 ENST00000369583.3
dual specificity phosphatase 5
chr17_+_60536002 2.89 ENST00000582809.1
tousled-like kinase 2
chr2_+_86947296 2.84 ENST00000283632.4
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr9_+_130911770 2.83 ENST00000372998.1
lipocalin 2
chr1_-_154943212 2.80 ENST00000368445.5
ENST00000448116.2
ENST00000368449.4
SHC (Src homology 2 domain containing) transforming protein 1
chr12_-_57504069 2.79 ENST00000543873.2
ENST00000554663.1
ENST00000557635.1
signal transducer and activator of transcription 6, interleukin-4 induced
chr1_-_202129704 2.74 ENST00000476061.1
ENST00000544762.1
ENST00000467283.1
ENST00000464870.1
ENST00000435759.2
ENST00000486116.1
ENST00000543735.1
ENST00000308986.5
ENST00000477625.1
protein tyrosine phosphatase, non-receptor type 7
chr19_-_45927097 2.74 ENST00000340192.7
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr6_+_31540056 2.68 ENST00000418386.2
lymphotoxin alpha
chr18_+_21529811 2.66 ENST00000588004.1
laminin, alpha 3
chr1_-_205744205 2.60 ENST00000446390.2
RAB7, member RAS oncogene family-like 1
chr8_-_145653885 2.60 ENST00000531032.1
ENST00000292510.4
ENST00000377348.2
ENST00000530790.1
ENST00000533806.1
vacuolar protein sorting 28 homolog (S. cerevisiae)
chr19_-_19051927 2.57 ENST00000600077.1
homer homolog 3 (Drosophila)
chr9_+_115913222 2.56 ENST00000259392.3
solute carrier family 31 (copper transporter), member 2
chr2_+_74056066 2.55 ENST00000339566.3
ENST00000409707.1
ENST00000452725.1
ENST00000432295.2
ENST00000424659.1
ENST00000394073.1
STAM binding protein
chr11_-_62380199 2.54 ENST00000419857.1
ENST00000394773.2
echinoderm microtubule associated protein like 3
chr17_-_53499310 2.52 ENST00000262065.3
monocyte to macrophage differentiation-associated
chr19_-_3786253 2.51 ENST00000585778.1
megakaryocyte-associated tyrosine kinase
chrX_-_1572629 2.49 ENST00000534940.1
acetylserotonin O-methyltransferase-like
chr14_+_96152754 2.49 ENST00000340722.7
T-cell leukemia/lymphoma 1B
chr19_-_10676666 2.48 ENST00000539027.1
ENST00000543682.1
ENST00000361821.5
ENST00000312962.6
KRI1 homolog (S. cerevisiae)
chr15_+_92396920 2.47 ENST00000318445.6
solute carrier organic anion transporter family, member 3A1
chr1_+_28879588 2.47 ENST00000373830.3
tRNA selenocysteine 1 associated protein 1
chr9_-_123691047 2.47 ENST00000373887.3
TNF receptor-associated factor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of NFKB2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 18.3 GO:1905154 negative regulation of eosinophil activation(GO:1902567) negative regulation of membrane invagination(GO:1905154) negative regulation of eosinophil migration(GO:2000417)
5.8 17.4 GO:0046730 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
5.2 15.7 GO:1990108 protein linear deubiquitination(GO:1990108)
4.4 48.0 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
4.0 16.0 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
4.0 11.9 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
3.9 3.9 GO:0002351 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
3.3 16.5 GO:0033591 response to L-ascorbic acid(GO:0033591)
3.2 9.5 GO:0044209 AMP salvage(GO:0044209)
3.1 9.2 GO:0002316 follicular B cell differentiation(GO:0002316) activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
2.9 22.9 GO:0032020 ISG15-protein conjugation(GO:0032020)
2.7 10.7 GO:0033277 abortive mitotic cell cycle(GO:0033277)
2.6 10.3 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
2.4 7.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
2.3 9.2 GO:0032218 riboflavin transport(GO:0032218)
2.1 12.7 GO:0022614 membrane to membrane docking(GO:0022614)
2.1 8.3 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
2.0 16.3 GO:0060155 platelet dense granule organization(GO:0060155)
2.0 8.1 GO:0000255 allantoin metabolic process(GO:0000255)
2.0 8.0 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
2.0 7.9 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
1.8 5.3 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
1.7 5.0 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
1.6 6.5 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
1.6 6.5 GO:0060623 regulation of chromosome condensation(GO:0060623)
1.6 15.7 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
1.5 4.5 GO:1905224 clathrin-coated pit assembly(GO:1905224)
1.5 7.5 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
1.4 5.7 GO:0002266 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
1.4 6.9 GO:0042631 cellular response to water deprivation(GO:0042631)
1.3 5.3 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
1.3 24.3 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
1.3 3.8 GO:0042938 dipeptide transport(GO:0042938)
1.2 6.1 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
1.2 6.0 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
1.2 17.6 GO:0097264 self proteolysis(GO:0097264)
1.1 8.9 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
1.1 5.3 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
1.0 10.4 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
1.0 3.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
1.0 4.0 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
1.0 3.9 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.9 10.4 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.9 2.8 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.9 4.6 GO:0002084 protein depalmitoylation(GO:0002084)
0.9 93.5 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.9 2.7 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.9 2.6 GO:2000395 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.8 8.4 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.8 4.9 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) positive regulation of t-circle formation(GO:1904431)
0.8 7.1 GO:0097167 circadian regulation of translation(GO:0097167)
0.8 2.3 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.7 12.4 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.7 3.6 GO:0007619 courtship behavior(GO:0007619)
0.7 15.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.7 4.6 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.6 3.7 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.6 6.9 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.6 7.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.6 1.8 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.6 11.2 GO:0032060 bleb assembly(GO:0032060)
0.6 1.7 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.5 8.6 GO:0045116 protein neddylation(GO:0045116)
0.5 4.0 GO:0070836 caveola assembly(GO:0070836)
0.5 3.9 GO:0051660 establishment of centrosome localization(GO:0051660)
0.5 3.3 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.5 3.6 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.4 4.0 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.4 3.5 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.4 3.0 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.4 3.3 GO:0035897 proteolysis in other organism(GO:0035897)
0.4 4.9 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.4 26.3 GO:0045773 positive regulation of axon extension(GO:0045773)
0.4 4.1 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.4 2.9 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.4 4.7 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.3 3.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.3 4.5 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.3 13.9 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.3 37.3 GO:0031295 T cell costimulation(GO:0031295)
0.3 4.8 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389) negative regulation of inclusion body assembly(GO:0090084)
0.3 9.6 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.3 7.1 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.3 16.6 GO:0006611 protein export from nucleus(GO:0006611)
0.3 47.9 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.3 4.0 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.3 14.7 GO:0006270 DNA replication initiation(GO:0006270)
0.3 2.6 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.3 4.8 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.3 2.5 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.3 3.3 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.2 2.5 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.2 0.9 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.2 4.4 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.2 8.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.2 2.5 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2 2.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 2.0 GO:0019732 antifungal humoral response(GO:0019732)
0.2 6.2 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.2 20.4 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.2 1.4 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.2 2.9 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.2 3.7 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.2 5.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 4.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 3.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.2 13.0 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.2 2.1 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.2 3.1 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.2 4.7 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.2 1.8 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.2 0.8 GO:0044782 cilium organization(GO:0044782)
0.2 0.5 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 1.7 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 2.1 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.2 0.5 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.2 0.3 GO:0035063 nuclear speck organization(GO:0035063)
0.1 1.7 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.9 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 3.7 GO:0044070 regulation of anion transport(GO:0044070)
0.1 7.9 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 6.2 GO:0043486 histone exchange(GO:0043486)
0.1 1.8 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.1 0.3 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 4.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 1.9 GO:0015732 prostaglandin transport(GO:0015732)
0.1 0.9 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.1 6.9 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 3.3 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 9.3 GO:0006334 nucleosome assembly(GO:0006334)
0.1 2.3 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.1 0.4 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.1 3.0 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.1 1.0 GO:0009249 protein lipoylation(GO:0009249)
0.1 2.4 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.1 1.3 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.1 3.5 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 4.7 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.9 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.1 2.4 GO:0009081 branched-chain amino acid metabolic process(GO:0009081)
0.1 0.4 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 2.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 8.8 GO:0002377 immunoglobulin production(GO:0002377)
0.1 1.3 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.1 0.7 GO:1904779 regulation of protein localization to centrosome(GO:1904779)
0.1 1.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 2.4 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.1 0.5 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.1 2.5 GO:0019835 cytolysis(GO:0019835)
0.0 1.9 GO:0006298 mismatch repair(GO:0006298)
0.0 1.8 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.2 GO:0045357 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 3.8 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.4 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 1.5 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 1.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 8.9 GO:0002250 adaptive immune response(GO:0002250)
0.0 8.3 GO:0006814 sodium ion transport(GO:0006814)
0.0 2.5 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.1 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.0 0.8 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 1.4 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.7 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 2.8 GO:0030534 adult behavior(GO:0030534)
0.0 1.2 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 2.5 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.8 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.4 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.1 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 3.2 GO:0007596 blood coagulation(GO:0007596)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
12.0 72.3 GO:0008537 proteasome activator complex(GO:0008537)
2.9 20.4 GO:0019815 B cell receptor complex(GO:0019815)
2.9 20.3 GO:0032584 growth cone membrane(GO:0032584)
2.7 21.2 GO:0032010 phagolysosome(GO:0032010)
2.4 7.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
1.7 36.7 GO:0042613 MHC class II protein complex(GO:0042613)
1.7 10.4 GO:0072557 IPAF inflammasome complex(GO:0072557)
1.7 5.0 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
1.6 4.8 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
1.4 15.7 GO:0042612 MHC class I protein complex(GO:0042612)
1.4 5.7 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
1.4 6.9 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
1.2 14.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
1.1 8.9 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
1.1 6.5 GO:0001740 Barr body(GO:0001740)
1.1 13.7 GO:0042555 MCM complex(GO:0042555)
1.0 10.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.9 2.8 GO:0034657 GID complex(GO:0034657)
0.9 10.3 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.8 3.3 GO:0032044 DSIF complex(GO:0032044)
0.8 14.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.7 4.3 GO:0070435 Shc-EGFR complex(GO:0070435)
0.7 16.4 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.7 5.6 GO:0005610 laminin-5 complex(GO:0005610)
0.7 4.9 GO:0070522 nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.6 48.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.6 9.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.5 4.5 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.5 2.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.5 1.9 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.5 1.4 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.5 3.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.4 38.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.4 1.7 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.4 2.0 GO:0005833 hemoglobin complex(GO:0005833)
0.4 3.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.4 5.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.4 2.6 GO:0000813 ESCRT I complex(GO:0000813)
0.4 7.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.3 1.0 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.3 14.4 GO:0097542 ciliary tip(GO:0097542)
0.3 23.4 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.3 7.9 GO:0000178 exosome (RNase complex)(GO:0000178)
0.3 3.0 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.3 6.2 GO:0000812 Swr1 complex(GO:0000812)
0.3 1.2 GO:0030314 junctional membrane complex(GO:0030314)
0.3 7.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.3 1.8 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 3.9 GO:0032059 bleb(GO:0032059)
0.2 3.9 GO:0097346 INO80-type complex(GO:0097346)
0.2 23.1 GO:0031594 neuromuscular junction(GO:0031594)
0.2 1.9 GO:0032389 MutLalpha complex(GO:0032389)
0.2 4.0 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 25.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.2 3.9 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.2 8.9 GO:0043034 costamere(GO:0043034)
0.2 5.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 7.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 2.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 23.4 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1 2.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 26.6 GO:0072562 blood microparticle(GO:0072562)
0.1 1.7 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.1 22.8 GO:0034774 secretory granule lumen(GO:0034774)
0.1 3.8 GO:0045178 basal part of cell(GO:0045178)
0.1 0.7 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.9 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 1.8 GO:0042627 chylomicron(GO:0042627)
0.1 3.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 5.0 GO:1990904 intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904)
0.1 2.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 8.9 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 2.5 GO:0030686 90S preribosome(GO:0030686)
0.1 2.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.9 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 3.3 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.1 5.3 GO:0016363 nuclear matrix(GO:0016363)
0.1 7.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 10.1 GO:0005795 Golgi stack(GO:0005795)
0.1 6.7 GO:0031902 late endosome membrane(GO:0031902)
0.1 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.9 GO:0031143 pseudopodium(GO:0031143)
0.1 0.7 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 2.3 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 10.8 GO:0030667 secretory granule membrane(GO:0030667)
0.0 5.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 4.3 GO:0030133 transport vesicle(GO:0030133)
0.0 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.0 7.5 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 14.2 GO:0016607 nuclear speck(GO:0016607)
0.0 8.1 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 2.9 GO:0005882 intermediate filament(GO:0005882)
0.0 2.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 3.0 GO:0016605 PML body(GO:0016605)
0.0 2.6 GO:0005770 late endosome(GO:0005770)
0.0 12.1 GO:0000785 chromatin(GO:0000785)
0.0 0.8 GO:0001533 cornified envelope(GO:0001533)
0.0 1.9 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.4 GO:0030496 midbody(GO:0030496)
0.0 3.3 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.2 GO:0005776 autophagosome(GO:0005776)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
10.3 72.3 GO:0061133 endopeptidase activator activity(GO:0061133)
6.1 24.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
5.8 17.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
3.8 22.9 GO:0042296 ISG15 transferase activity(GO:0042296)
3.4 10.3 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
2.6 36.7 GO:0032395 MHC class II receptor activity(GO:0032395)
2.5 17.4 GO:0004046 aminoacylase activity(GO:0004046)
2.4 7.3 GO:0017130 poly(C) RNA binding(GO:0017130)
2.4 9.5 GO:0002060 purine nucleobase binding(GO:0002060)
2.4 7.1 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
2.3 9.2 GO:0032217 riboflavin transporter activity(GO:0032217)
2.3 16.0 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
2.1 21.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
2.0 7.9 GO:0034057 RNA strand-exchange activity(GO:0034057)
1.6 8.0 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
1.6 15.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
1.4 18.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
1.4 8.3 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
1.3 5.3 GO:0031493 nucleosomal histone binding(GO:0031493)
1.3 17.9 GO:0050700 CARD domain binding(GO:0050700)
1.1 3.3 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
1.1 6.5 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.9 20.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.8 13.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.8 7.9 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.7 2.9 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.7 4.9 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.7 2.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.7 15.2 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.6 10.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.6 3.7 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.6 4.3 GO:0048408 epidermal growth factor binding(GO:0048408)
0.6 3.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.6 9.2 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.6 22.4 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.6 4.6 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.5 15.7 GO:0042605 peptide antigen binding(GO:0042605)
0.5 3.1 GO:0030492 hemoglobin binding(GO:0030492)
0.5 3.9 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.5 5.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.5 3.8 GO:0004064 arylesterase activity(GO:0004064)
0.5 3.6 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.5 8.6 GO:0097602 cullin family protein binding(GO:0097602)
0.4 1.7 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.4 4.7 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.4 16.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.4 1.7 GO:0005046 KDEL sequence binding(GO:0005046)
0.4 6.0 GO:0001222 transcription corepressor binding(GO:0001222)
0.4 10.7 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.4 4.1 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.4 3.7 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.4 66.1 GO:0003823 antigen binding(GO:0003823)
0.4 3.9 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.3 4.8 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.3 9.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.3 10.4 GO:0019956 chemokine binding(GO:0019956)
0.3 0.9 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.3 1.4 GO:0070026 nitric oxide binding(GO:0070026)
0.3 13.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.3 4.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 4.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.3 1.6 GO:0050692 DBD domain binding(GO:0050692)
0.3 1.8 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.3 2.6 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.2 5.1 GO:0070300 phosphatidic acid binding(GO:0070300)
0.2 11.9 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.2 1.0 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.2 1.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2 1.9 GO:0043559 insulin binding(GO:0043559)
0.2 1.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2 2.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 1.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.2 0.8 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 2.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.2 1.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 12.8 GO:0070063 RNA polymerase binding(GO:0070063)
0.2 2.5 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2 3.2 GO:0048156 tau protein binding(GO:0048156)
0.2 5.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2 41.8 GO:0019887 protein kinase regulator activity(GO:0019887)
0.2 8.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 8.8 GO:0000049 tRNA binding(GO:0000049)
0.2 6.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.2 29.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 3.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 8.4 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.2 6.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 4.8 GO:0001671 ATPase activator activity(GO:0001671)
0.1 2.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 3.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 3.3 GO:0005123 death receptor binding(GO:0005123)
0.1 2.3 GO:0016502 G-protein coupled nucleotide receptor activity(GO:0001608) purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.4 GO:0044388 superoxide dismutase copper chaperone activity(GO:0016532) small protein activating enzyme binding(GO:0044388)
0.1 21.1 GO:0005178 integrin binding(GO:0005178)
0.1 0.5 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 4.0 GO:0015248 sterol transporter activity(GO:0015248)
0.1 4.5 GO:0030332 cyclin binding(GO:0030332)
0.1 0.7 GO:0030274 LIM domain binding(GO:0030274)
0.1 12.9 GO:0005262 calcium channel activity(GO:0005262)
0.1 1.8 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 3.0 GO:0001618 virus receptor activity(GO:0001618)
0.1 1.9 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.7 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 2.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.6 GO:0008242 omega peptidase activity(GO:0008242)
0.1 1.9 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 1.8 GO:0008143 poly(A) binding(GO:0008143)
0.1 3.7 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 4.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.4 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 3.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 2.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 3.9 GO:0046332 SMAD binding(GO:0046332)
0.0 5.7 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.0 1.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 2.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 1.1 GO:0043621 protein self-association(GO:0043621)
0.0 0.8 GO:0050699 WW domain binding(GO:0050699)
0.0 1.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0010851 cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.5 GO:0051117 ATPase binding(GO:0051117)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 73.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.9 7.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.8 23.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.7 25.0 PID IL27 PATHWAY IL27-mediated signaling events
0.6 24.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.5 40.8 PID BCR 5PATHWAY BCR signaling pathway
0.5 7.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.5 41.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.4 4.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.4 25.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.4 12.7 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.3 17.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.3 7.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.3 9.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.3 6.4 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.3 7.5 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.3 19.0 PID FOXO PATHWAY FoxO family signaling
0.2 2.8 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.2 9.1 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 5.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 9.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 2.5 PID CD40 PATHWAY CD40/CD40L signaling
0.1 1.7 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 1.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.7 PID ARF 3PATHWAY Arf1 pathway
0.1 3.9 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 3.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 2.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 3.2 PID AP1 PATHWAY AP-1 transcription factor network
0.0 3.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 3.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.0 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 4.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.4 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.8 PID ATM PATHWAY ATM pathway
0.0 1.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 36.7 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
1.6 15.7 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
1.4 15.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
1.3 35.0 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
1.2 17.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
1.2 63.5 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
1.1 10.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
1.1 15.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
1.0 72.3 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.9 13.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.8 21.2 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.8 10.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.7 33.7 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.7 16.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.7 24.7 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.6 8.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.6 12.6 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.6 3.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.5 5.6 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.4 27.7 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.4 2.6 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.4 5.5 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.3 12.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.3 8.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.3 10.8 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.3 8.5 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.3 11.1 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.3 8.1 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.3 7.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.3 9.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.3 3.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 5.6 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.2 3.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 10.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2 4.7 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.2 15.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 5.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.2 3.3 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.2 2.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 6.7 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.2 6.4 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.2 1.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.2 4.9 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.2 10.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 5.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.2 2.9 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 3.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 2.0 REACTOME DEFENSINS Genes involved in Defensins
0.1 7.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 2.9 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 6.5 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 2.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 2.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 7.9 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.1 2.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 2.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 3.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 1.0 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 8.8 REACTOME TRANSLATION Genes involved in Translation
0.1 0.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.0 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 2.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 4.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 2.3 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.6 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 2.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC