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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for NKX2-3
Z-value: 0.65
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Transcription factors associated with NKX2-3
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
NKX2-3
|
ENSG00000119919.9 | NK2 homeobox 3 |
Activity profile of NKX2-3 motif
Sorted Z-values of NKX2-3 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr5_+_150404904 | 32.59 |
ENST00000521632.1
|
GPX3
|
glutathione peroxidase 3 (plasma) |
| chr4_-_84035868 | 7.69 |
ENST00000426923.2
ENST00000509973.1 |
PLAC8
|
placenta-specific 8 |
| chr4_-_84035905 | 7.56 |
ENST00000311507.4
|
PLAC8
|
placenta-specific 8 |
| chr11_+_10326612 | 5.28 |
ENST00000534464.1
ENST00000530439.1 ENST00000524948.1 ENST00000528655.1 ENST00000526492.1 ENST00000525063.1 |
ADM
|
adrenomedullin |
| chr17_-_76870222 | 5.04 |
ENST00000585421.1
|
TIMP2
|
TIMP metallopeptidase inhibitor 2 |
| chr17_-_76870126 | 4.96 |
ENST00000586057.1
|
TIMP2
|
TIMP metallopeptidase inhibitor 2 |
| chr11_+_35211429 | 4.64 |
ENST00000525688.1
ENST00000278385.6 ENST00000533222.1 |
CD44
|
CD44 molecule (Indian blood group) |
| chr3_-_123512688 | 4.31 |
ENST00000475616.1
|
MYLK
|
myosin light chain kinase |
| chr17_-_8055747 | 4.24 |
ENST00000317276.4
ENST00000581703.1 |
PER1
|
period circadian clock 1 |
| chr9_-_137809718 | 4.16 |
ENST00000371806.3
|
FCN1
|
ficolin (collagen/fibrinogen domain containing) 1 |
| chr20_-_4795747 | 4.16 |
ENST00000379376.2
|
RASSF2
|
Ras association (RalGDS/AF-6) domain family member 2 |
| chr4_-_100242549 | 4.14 |
ENST00000305046.8
ENST00000394887.3 |
ADH1B
|
alcohol dehydrogenase 1B (class I), beta polypeptide |
| chr7_-_76829125 | 3.53 |
ENST00000248598.5
|
FGL2
|
fibrinogen-like 2 |
| chr1_+_54359854 | 3.47 |
ENST00000361921.3
ENST00000322679.6 ENST00000532493.1 ENST00000525202.1 ENST00000524406.1 ENST00000388876.3 |
DIO1
|
deiodinase, iodothyronine, type I |
| chr4_-_46911223 | 3.32 |
ENST00000396533.1
|
COX7B2
|
cytochrome c oxidase subunit VIIb2 |
| chr9_+_118950325 | 3.28 |
ENST00000534838.1
|
PAPPA
|
pregnancy-associated plasma protein A, pappalysin 1 |
| chr17_-_29641084 | 3.17 |
ENST00000544462.1
|
EVI2B
|
ecotropic viral integration site 2B |
| chr11_+_35211511 | 3.13 |
ENST00000524922.1
|
CD44
|
CD44 molecule (Indian blood group) |
| chr4_-_46911248 | 3.13 |
ENST00000355591.3
ENST00000505102.1 |
COX7B2
|
cytochrome c oxidase subunit VIIb2 |
| chr12_-_123201337 | 3.02 |
ENST00000528880.2
|
HCAR3
|
hydroxycarboxylic acid receptor 3 |
| chr3_+_30648066 | 2.98 |
ENST00000359013.4
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa) |
| chr17_-_29641104 | 2.97 |
ENST00000577894.1
ENST00000330927.4 |
EVI2B
|
ecotropic viral integration site 2B |
| chr2_-_38303218 | 2.93 |
ENST00000407341.1
ENST00000260630.3 |
CYP1B1
|
cytochrome P450, family 1, subfamily B, polypeptide 1 |
| chr9_+_116263778 | 2.90 |
ENST00000394646.3
|
RGS3
|
regulator of G-protein signaling 3 |
| chr19_-_44174330 | 2.85 |
ENST00000340093.3
|
PLAUR
|
plasminogen activator, urokinase receptor |
| chr15_-_78369994 | 2.83 |
ENST00000300584.3
ENST00000409931.3 |
TBC1D2B
|
TBC1 domain family, member 2B |
| chr19_+_14492247 | 2.68 |
ENST00000357355.3
ENST00000592261.2 ENST00000242786.5 |
CD97
|
CD97 molecule |
| chr7_-_29186008 | 2.68 |
ENST00000396276.3
ENST00000265394.5 |
CPVL
|
carboxypeptidase, vitellogenic-like |
| chr4_+_76439665 | 2.68 |
ENST00000508105.1
ENST00000311638.3 ENST00000380837.3 ENST00000507556.1 ENST00000504190.1 ENST00000507885.1 ENST00000502620.1 ENST00000514480.1 |
THAP6
|
THAP domain containing 6 |
| chr6_-_137539651 | 2.66 |
ENST00000543628.1
|
IFNGR1
|
interferon gamma receptor 1 |
| chr3_+_30647994 | 2.65 |
ENST00000295754.5
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa) |
| chr3_-_114790179 | 2.56 |
ENST00000462705.1
|
ZBTB20
|
zinc finger and BTB domain containing 20 |
| chr10_+_135207598 | 2.48 |
ENST00000477902.2
|
MTG1
|
mitochondrial ribosome-associated GTPase 1 |
| chr12_-_123187890 | 2.44 |
ENST00000328880.5
|
HCAR2
|
hydroxycarboxylic acid receptor 2 |
| chr8_+_134125727 | 2.40 |
ENST00000521107.1
|
TG
|
thyroglobulin |
| chr10_+_135207623 | 2.37 |
ENST00000317502.6
ENST00000432508.3 |
MTG1
|
mitochondrial ribosome-associated GTPase 1 |
| chr11_-_111175739 | 2.35 |
ENST00000532918.1
|
COLCA1
|
colorectal cancer associated 1 |
| chr1_-_35325400 | 2.34 |
ENST00000521580.2
|
SMIM12
|
small integral membrane protein 12 |
| chr6_-_33285505 | 2.31 |
ENST00000431845.2
|
ZBTB22
|
zinc finger and BTB domain containing 22 |
| chr19_+_45409011 | 2.29 |
ENST00000252486.4
ENST00000446996.1 ENST00000434152.1 |
APOE
|
apolipoprotein E |
| chr4_-_57524061 | 2.21 |
ENST00000508121.1
|
HOPX
|
HOP homeobox |
| chr1_-_79472365 | 2.18 |
ENST00000370742.3
|
ELTD1
|
EGF, latrophilin and seven transmembrane domain containing 1 |
| chr19_+_14491948 | 2.17 |
ENST00000358600.3
|
CD97
|
CD97 molecule |
| chr9_-_116840728 | 2.10 |
ENST00000265132.3
|
AMBP
|
alpha-1-microglobulin/bikunin precursor |
| chr6_-_32160622 | 2.10 |
ENST00000487761.1
ENST00000375040.3 |
GPSM3
|
G-protein signaling modulator 3 |
| chr1_+_202317815 | 2.08 |
ENST00000608999.1
ENST00000336894.4 ENST00000480184.1 |
PPP1R12B
|
protein phosphatase 1, regulatory subunit 12B |
| chr6_-_144329531 | 2.05 |
ENST00000429150.1
ENST00000392309.1 ENST00000416623.1 ENST00000392307.1 |
PLAGL1
|
pleiomorphic adenoma gene-like 1 |
| chr5_+_49961727 | 2.04 |
ENST00000505697.2
ENST00000503750.2 ENST00000514342.2 |
PARP8
|
poly (ADP-ribose) polymerase family, member 8 |
| chr9_+_36036430 | 2.00 |
ENST00000377966.3
|
RECK
|
reversion-inducing-cysteine-rich protein with kazal motifs |
| chr12_+_10460549 | 1.97 |
ENST00000543420.1
ENST00000543777.1 |
KLRD1
|
killer cell lectin-like receptor subfamily D, member 1 |
| chr19_+_17622415 | 1.96 |
ENST00000252603.2
ENST00000600923.1 |
PGLS
|
6-phosphogluconolactonase |
| chr5_-_142814241 | 1.96 |
ENST00000504572.1
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| chr3_+_38179969 | 1.93 |
ENST00000396334.3
ENST00000417037.2 ENST00000424893.1 ENST00000495303.1 ENST00000443433.2 ENST00000421516.1 |
MYD88
|
myeloid differentiation primary response 88 |
| chr12_+_10460417 | 1.92 |
ENST00000381908.3
ENST00000336164.4 ENST00000350274.5 |
KLRD1
|
killer cell lectin-like receptor subfamily D, member 1 |
| chr4_+_80584903 | 1.90 |
ENST00000506460.1
|
RP11-452C8.1
|
RP11-452C8.1 |
| chr3_-_122134882 | 1.89 |
ENST00000330689.4
|
WDR5B
|
WD repeat domain 5B |
| chr6_-_32634425 | 1.88 |
ENST00000399082.3
ENST00000399079.3 ENST00000374943.4 ENST00000434651.2 |
HLA-DQB1
|
major histocompatibility complex, class II, DQ beta 1 |
| chr17_+_66521936 | 1.84 |
ENST00000592800.1
|
PRKAR1A
|
protein kinase, cAMP-dependent, regulatory, type I, alpha |
| chr12_-_122296755 | 1.82 |
ENST00000289004.4
|
HPD
|
4-hydroxyphenylpyruvate dioxygenase |
| chr3_-_36986534 | 1.80 |
ENST00000429976.2
ENST00000301807.6 |
TRANK1
|
tetratricopeptide repeat and ankyrin repeat containing 1 |
| chr12_+_111051832 | 1.72 |
ENST00000550703.2
ENST00000551590.1 |
TCTN1
|
tectonic family member 1 |
| chr17_+_29248698 | 1.67 |
ENST00000330889.3
|
ADAP2
|
ArfGAP with dual PH domains 2 |
| chr6_-_11382478 | 1.65 |
ENST00000397378.3
ENST00000513989.1 ENST00000508546.1 ENST00000504387.1 |
NEDD9
|
neural precursor cell expressed, developmentally down-regulated 9 |
| chr13_-_50018241 | 1.65 |
ENST00000409308.1
|
CAB39L
|
calcium binding protein 39-like |
| chr10_-_70092671 | 1.64 |
ENST00000358769.2
ENST00000432941.1 ENST00000495025.2 |
PBLD
|
phenazine biosynthesis-like protein domain containing |
| chr4_-_100212132 | 1.62 |
ENST00000209668.2
|
ADH1A
|
alcohol dehydrogenase 1A (class I), alpha polypeptide |
| chr17_+_58227287 | 1.59 |
ENST00000300900.4
ENST00000591725.1 |
CA4
|
carbonic anhydrase IV |
| chr12_-_48398104 | 1.58 |
ENST00000337299.6
ENST00000380518.3 |
COL2A1
|
collagen, type II, alpha 1 |
| chr16_+_69221028 | 1.58 |
ENST00000336278.4
|
SNTB2
|
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) |
| chr5_-_70320941 | 1.58 |
ENST00000523981.1
|
NAIP
|
NLR family, apoptosis inhibitory protein |
| chr14_+_21423611 | 1.56 |
ENST00000304625.2
|
RNASE2
|
ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| chr5_+_149569520 | 1.55 |
ENST00000230671.2
ENST00000524041.1 |
SLC6A7
|
solute carrier family 6 (neurotransmitter transporter), member 7 |
| chr12_+_111051902 | 1.51 |
ENST00000397655.3
ENST00000471804.2 ENST00000377654.3 ENST00000397659.4 |
TCTN1
|
tectonic family member 1 |
| chr1_-_155990580 | 1.47 |
ENST00000531917.1
ENST00000480567.1 ENST00000526212.1 ENST00000529008.1 ENST00000496742.1 ENST00000295702.4 |
SSR2
|
signal sequence receptor, beta (translocon-associated protein beta) |
| chr13_-_50018140 | 1.45 |
ENST00000410043.1
ENST00000347776.5 |
CAB39L
|
calcium binding protein 39-like |
| chr12_-_125398654 | 1.44 |
ENST00000541645.1
ENST00000540351.1 |
UBC
|
ubiquitin C |
| chrX_+_47420516 | 1.44 |
ENST00000377045.4
ENST00000290277.6 ENST00000377039.2 |
ARAF
|
v-raf murine sarcoma 3611 viral oncogene homolog |
| chr14_-_93214915 | 1.43 |
ENST00000553918.1
ENST00000555699.1 ENST00000553802.1 ENST00000554397.1 ENST00000554919.1 ENST00000554080.1 ENST00000553371.1 |
LGMN
|
legumain |
| chr3_+_186560476 | 1.38 |
ENST00000320741.2
ENST00000444204.2 |
ADIPOQ
|
adiponectin, C1Q and collagen domain containing |
| chr3_+_186560462 | 1.37 |
ENST00000412955.2
|
ADIPOQ
|
adiponectin, C1Q and collagen domain containing |
| chr14_-_60636561 | 1.37 |
ENST00000536410.2
ENST00000216500.5 |
DHRS7
|
dehydrogenase/reductase (SDR family) member 7 |
| chr2_+_219110149 | 1.35 |
ENST00000456575.1
|
ARPC2
|
actin related protein 2/3 complex, subunit 2, 34kDa |
| chr2_-_89597542 | 1.34 |
ENST00000465170.1
|
IGKV1-37
|
immunoglobulin kappa variable 1-37 (non-functional) |
| chr6_-_32731299 | 1.33 |
ENST00000435145.2
ENST00000437316.2 |
HLA-DQB2
|
major histocompatibility complex, class II, DQ beta 2 |
| chr6_-_33239712 | 1.33 |
ENST00000436044.2
|
VPS52
|
vacuolar protein sorting 52 homolog (S. cerevisiae) |
| chr8_-_49833978 | 1.31 |
ENST00000020945.1
|
SNAI2
|
snail family zinc finger 2 |
| chr10_-_104262460 | 1.30 |
ENST00000446605.2
ENST00000369905.4 ENST00000545684.1 |
ACTR1A
|
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) |
| chr14_-_90798418 | 1.30 |
ENST00000354366.3
|
NRDE2
|
NRDE-2, necessary for RNA interference, domain containing |
| chr2_-_36825281 | 1.29 |
ENST00000405912.3
ENST00000379245.4 |
FEZ2
|
fasciculation and elongation protein zeta 2 (zygin II) |
| chr12_-_125398850 | 1.28 |
ENST00000535859.1
ENST00000546271.1 ENST00000540700.1 ENST00000546120.1 |
UBC
|
ubiquitin C |
| chr19_-_42746714 | 1.27 |
ENST00000222330.3
|
GSK3A
|
glycogen synthase kinase 3 alpha |
| chr7_+_134430212 | 1.27 |
ENST00000436461.2
|
CALD1
|
caldesmon 1 |
| chr11_+_12399071 | 1.26 |
ENST00000539723.1
ENST00000550549.1 |
PARVA
|
parvin, alpha |
| chr1_-_200379104 | 1.25 |
ENST00000367352.3
|
ZNF281
|
zinc finger protein 281 |
| chr13_-_46756351 | 1.24 |
ENST00000323076.2
|
LCP1
|
lymphocyte cytosolic protein 1 (L-plastin) |
| chr2_+_89923550 | 1.22 |
ENST00000509129.1
|
IGKV1D-37
|
immunoglobulin kappa variable 1D-37 (non-functional) |
| chr3_+_39093481 | 1.20 |
ENST00000302313.5
ENST00000544962.1 ENST00000396258.3 ENST00000418020.1 |
WDR48
|
WD repeat domain 48 |
| chr16_-_3450963 | 1.20 |
ENST00000573327.1
ENST00000571906.1 ENST00000573830.1 ENST00000439568.2 ENST00000422427.2 ENST00000304926.3 ENST00000396852.4 |
ZSCAN32
|
zinc finger and SCAN domain containing 32 |
| chr1_-_165668100 | 1.19 |
ENST00000354775.4
|
ALDH9A1
|
aldehyde dehydrogenase 9 family, member A1 |
| chr16_-_66952742 | 1.18 |
ENST00000565235.2
ENST00000568632.1 ENST00000565796.1 |
CDH16
|
cadherin 16, KSP-cadherin |
| chr19_+_3178736 | 1.18 |
ENST00000246115.3
|
S1PR4
|
sphingosine-1-phosphate receptor 4 |
| chr4_+_88754113 | 1.14 |
ENST00000560249.1
ENST00000540395.1 ENST00000511670.1 ENST00000361056.3 |
MEPE
|
matrix extracellular phosphoglycoprotein |
| chr1_-_29508321 | 1.12 |
ENST00000546138.1
|
SRSF4
|
serine/arginine-rich splicing factor 4 |
| chr15_+_33022885 | 1.12 |
ENST00000322805.4
|
GREM1
|
gremlin 1, DAN family BMP antagonist |
| chr4_-_104021009 | 1.12 |
ENST00000509245.1
ENST00000296424.4 |
BDH2
|
3-hydroxybutyrate dehydrogenase, type 2 |
| chr5_-_141338627 | 1.10 |
ENST00000231484.3
|
PCDH12
|
protocadherin 12 |
| chr8_-_49834299 | 1.09 |
ENST00000396822.1
|
SNAI2
|
snail family zinc finger 2 |
| chr10_-_104262426 | 1.08 |
ENST00000487599.1
|
ACTR1A
|
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) |
| chr17_+_42264322 | 1.08 |
ENST00000446571.3
ENST00000357984.3 ENST00000538716.2 |
TMUB2
|
transmembrane and ubiquitin-like domain containing 2 |
| chr16_+_56969284 | 1.08 |
ENST00000568358.1
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| chr12_-_110434096 | 1.07 |
ENST00000320063.9
ENST00000457474.2 ENST00000547815.1 ENST00000361006.5 |
GIT2
|
G protein-coupled receptor kinase interacting ArfGAP 2 |
| chr5_-_39270725 | 1.06 |
ENST00000512138.1
ENST00000512982.1 ENST00000540520.1 |
FYB
|
FYN binding protein |
| chr2_+_173420697 | 1.02 |
ENST00000282077.3
ENST00000392571.2 ENST00000410055.1 |
PDK1
|
pyruvate dehydrogenase kinase, isozyme 1 |
| chr3_-_3221358 | 1.01 |
ENST00000424814.1
ENST00000450014.1 ENST00000231948.4 ENST00000432408.2 |
CRBN
|
cereblon |
| chr4_-_36246060 | 0.98 |
ENST00000303965.4
|
ARAP2
|
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| chr7_-_86849883 | 0.96 |
ENST00000433078.1
|
TMEM243
|
transmembrane protein 243, mitochondrial |
| chr6_-_2971494 | 0.95 |
ENST00000380539.1
|
SERPINB6
|
serpin peptidase inhibitor, clade B (ovalbumin), member 6 |
| chr3_-_49761337 | 0.93 |
ENST00000535833.1
ENST00000308388.6 ENST00000480687.1 ENST00000308375.6 |
AMIGO3
GMPPB
|
adhesion molecule with Ig-like domain 3 GDP-mannose pyrophosphorylase B |
| chr18_-_51750948 | 0.93 |
ENST00000583046.1
ENST00000398398.2 |
MBD2
|
methyl-CpG binding domain protein 2 |
| chr13_-_46679185 | 0.93 |
ENST00000439329.3
|
CPB2
|
carboxypeptidase B2 (plasma) |
| chr19_+_39616410 | 0.92 |
ENST00000602004.1
ENST00000599470.1 ENST00000321944.4 ENST00000593480.1 ENST00000358301.3 ENST00000593690.1 ENST00000599386.1 |
PAK4
|
p21 protein (Cdc42/Rac)-activated kinase 4 |
| chr7_-_2883928 | 0.91 |
ENST00000275364.3
|
GNA12
|
guanine nucleotide binding protein (G protein) alpha 12 |
| chr22_+_38453207 | 0.91 |
ENST00000404072.3
ENST00000424694.1 |
PICK1
|
protein interacting with PRKCA 1 |
| chr1_-_29508499 | 0.90 |
ENST00000373795.4
|
SRSF4
|
serine/arginine-rich splicing factor 4 |
| chr2_+_202125219 | 0.90 |
ENST00000323492.7
|
CASP8
|
caspase 8, apoptosis-related cysteine peptidase |
| chr5_+_156693091 | 0.89 |
ENST00000318218.6
ENST00000442283.2 ENST00000522463.1 ENST00000521420.1 |
CYFIP2
|
cytoplasmic FMR1 interacting protein 2 |
| chr13_-_46679144 | 0.89 |
ENST00000181383.4
|
CPB2
|
carboxypeptidase B2 (plasma) |
| chr14_-_95624227 | 0.89 |
ENST00000526495.1
|
DICER1
|
dicer 1, ribonuclease type III |
| chr15_+_58702742 | 0.87 |
ENST00000356113.6
ENST00000414170.3 |
LIPC
|
lipase, hepatic |
| chr1_-_213188772 | 0.87 |
ENST00000544555.1
|
ANGEL2
|
angel homolog 2 (Drosophila) |
| chr1_-_151804314 | 0.87 |
ENST00000318247.6
|
RORC
|
RAR-related orphan receptor C |
| chr6_-_33239612 | 0.87 |
ENST00000482399.1
ENST00000445902.2 |
VPS52
|
vacuolar protein sorting 52 homolog (S. cerevisiae) |
| chr3_-_150920979 | 0.86 |
ENST00000309180.5
ENST00000480322.1 |
GPR171
|
G protein-coupled receptor 171 |
| chr19_-_19051993 | 0.85 |
ENST00000594794.1
ENST00000355887.6 ENST00000392351.3 ENST00000596482.1 |
HOMER3
|
homer homolog 3 (Drosophila) |
| chr20_-_23969416 | 0.84 |
ENST00000335694.4
|
GGTLC1
|
gamma-glutamyltransferase light chain 1 |
| chr17_-_26662440 | 0.82 |
ENST00000578122.1
|
IFT20
|
intraflagellar transport 20 homolog (Chlamydomonas) |
| chr1_-_19746236 | 0.81 |
ENST00000375144.1
|
CAPZB
|
capping protein (actin filament) muscle Z-line, beta |
| chr12_+_9980113 | 0.80 |
ENST00000537723.1
|
KLRF1
|
killer cell lectin-like receptor subfamily F, member 1 |
| chr4_+_88754069 | 0.80 |
ENST00000395102.4
ENST00000497649.2 |
MEPE
|
matrix extracellular phosphoglycoprotein |
| chr12_-_48119301 | 0.79 |
ENST00000545824.2
ENST00000422538.3 |
ENDOU
|
endonuclease, polyU-specific |
| chr7_-_87342564 | 0.78 |
ENST00000265724.3
ENST00000416177.1 |
ABCB1
|
ATP-binding cassette, sub-family B (MDR/TAP), member 1 |
| chr4_-_48082192 | 0.77 |
ENST00000507351.1
|
TXK
|
TXK tyrosine kinase |
| chr16_-_66952779 | 0.77 |
ENST00000570262.1
ENST00000394055.3 ENST00000299752.4 |
CDH16
|
cadherin 16, KSP-cadherin |
| chr6_-_46048116 | 0.76 |
ENST00000185206.6
|
CLIC5
|
chloride intracellular channel 5 |
| chr5_-_180688105 | 0.74 |
ENST00000327767.4
|
TRIM52
|
tripartite motif containing 52 |
| chr7_-_80548667 | 0.73 |
ENST00000265361.3
|
SEMA3C
|
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
| chr8_-_101718991 | 0.73 |
ENST00000517990.1
|
PABPC1
|
poly(A) binding protein, cytoplasmic 1 |
| chr12_+_14572070 | 0.70 |
ENST00000545769.1
ENST00000428217.2 ENST00000396279.2 ENST00000542514.1 ENST00000536279.1 |
ATF7IP
|
activating transcription factor 7 interacting protein |
| chr10_-_36813162 | 0.69 |
ENST00000440465.1
|
NAMPTL
|
nicotinamide phosphoribosyltransferase-like |
| chr14_+_102276192 | 0.68 |
ENST00000557714.1
|
PPP2R5C
|
protein phosphatase 2, regulatory subunit B', gamma |
| chr18_+_61445007 | 0.68 |
ENST00000447428.1
ENST00000546027.1 |
SERPINB7
|
serpin peptidase inhibitor, clade B (ovalbumin), member 7 |
| chr11_-_62389449 | 0.68 |
ENST00000534026.1
|
B3GAT3
|
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) |
| chr17_+_26662730 | 0.67 |
ENST00000226225.2
|
TNFAIP1
|
tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| chr20_-_33735070 | 0.67 |
ENST00000374491.3
ENST00000542871.1 ENST00000374492.3 |
EDEM2
|
ER degradation enhancer, mannosidase alpha-like 2 |
| chr17_-_26662464 | 0.67 |
ENST00000579419.1
ENST00000585313.1 ENST00000395418.3 ENST00000578985.1 ENST00000577498.1 ENST00000585089.1 ENST00000357896.3 |
IFT20
|
intraflagellar transport 20 homolog (Chlamydomonas) |
| chr10_+_101419187 | 0.67 |
ENST00000370489.4
|
ENTPD7
|
ectonucleoside triphosphate diphosphohydrolase 7 |
| chr4_-_141677267 | 0.67 |
ENST00000442267.2
|
TBC1D9
|
TBC1 domain family, member 9 (with GRAM domain) |
| chr8_+_28196157 | 0.64 |
ENST00000522209.1
|
PNOC
|
prepronociceptin |
| chr3_+_98482175 | 0.63 |
ENST00000485391.1
ENST00000492254.1 |
ST3GAL6
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
| chr11_+_124735282 | 0.62 |
ENST00000397801.1
|
ROBO3
|
roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| chr10_+_35464513 | 0.61 |
ENST00000494479.1
ENST00000463314.1 ENST00000342105.3 ENST00000495301.1 ENST00000463960.1 |
CREM
|
cAMP responsive element modulator |
| chr19_-_39881669 | 0.60 |
ENST00000221266.7
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) |
| chr10_+_99332529 | 0.60 |
ENST00000455090.1
|
ANKRD2
|
ankyrin repeat domain 2 (stretch responsive muscle) |
| chr18_-_13915530 | 0.59 |
ENST00000327606.3
|
MC2R
|
melanocortin 2 receptor (adrenocorticotropic hormone) |
| chr12_+_101988774 | 0.58 |
ENST00000545503.2
ENST00000536007.1 ENST00000541119.1 ENST00000361466.2 ENST00000551300.1 ENST00000550270.1 |
MYBPC1
|
myosin binding protein C, slow type |
| chr12_-_48119340 | 0.58 |
ENST00000229003.3
|
ENDOU
|
endonuclease, polyU-specific |
| chr4_-_120550146 | 0.58 |
ENST00000354960.3
|
PDE5A
|
phosphodiesterase 5A, cGMP-specific |
| chr6_-_32731243 | 0.57 |
ENST00000427449.1
ENST00000411527.1 |
HLA-DQB2
|
major histocompatibility complex, class II, DQ beta 2 |
| chr1_+_41157671 | 0.57 |
ENST00000534399.1
ENST00000372653.1 |
NFYC
|
nuclear transcription factor Y, gamma |
| chr1_-_216896780 | 0.56 |
ENST00000459955.1
ENST00000366937.1 ENST00000408911.3 ENST00000391890.3 |
ESRRG
|
estrogen-related receptor gamma |
| chr10_+_99332198 | 0.55 |
ENST00000307518.5
ENST00000298808.5 ENST00000370655.1 |
ANKRD2
|
ankyrin repeat domain 2 (stretch responsive muscle) |
| chr3_-_125802765 | 0.55 |
ENST00000514891.1
ENST00000512470.1 ENST00000504035.1 ENST00000360370.4 ENST00000513723.1 ENST00000510651.1 ENST00000514333.1 |
SLC41A3
|
solute carrier family 41, member 3 |
| chr19_-_1401486 | 0.54 |
ENST00000252288.2
ENST00000447102.3 |
GAMT
|
guanidinoacetate N-methyltransferase |
| chr3_+_108541545 | 0.53 |
ENST00000295756.6
|
TRAT1
|
T cell receptor associated transmembrane adaptor 1 |
| chr2_+_90458201 | 0.53 |
ENST00000603238.1
|
CH17-132F21.1
|
Uncharacterized protein |
| chr1_-_175712665 | 0.52 |
ENST00000263525.2
|
TNR
|
tenascin R |
| chr20_-_43729750 | 0.51 |
ENST00000537075.1
ENST00000306117.1 |
KCNS1
|
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1 |
| chr13_-_99910673 | 0.50 |
ENST00000397473.2
ENST00000397470.2 |
GPR18
|
G protein-coupled receptor 18 |
| chr9_-_99382065 | 0.49 |
ENST00000265659.2
ENST00000375241.1 ENST00000375236.1 |
CDC14B
|
cell division cycle 14B |
| chr4_+_95376396 | 0.49 |
ENST00000508216.1
ENST00000514743.1 |
PDLIM5
|
PDZ and LIM domain 5 |
| chr3_+_183967409 | 0.48 |
ENST00000324557.4
ENST00000402825.3 |
ECE2
|
endothelin converting enzyme 2 |
| chr6_+_33239787 | 0.48 |
ENST00000439602.2
ENST00000474973.1 |
RPS18
|
ribosomal protein S18 |
| chr11_-_62342375 | 0.48 |
ENST00000378019.3
|
EEF1G
|
eukaryotic translation elongation factor 1 gamma |
| chr2_+_71357744 | 0.47 |
ENST00000498451.2
|
MPHOSPH10
|
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) |
| chr8_-_20040601 | 0.46 |
ENST00000265808.7
ENST00000522513.1 |
SLC18A1
|
solute carrier family 18 (vesicular monoamine transporter), member 1 |
| chr12_+_123464607 | 0.46 |
ENST00000543566.1
ENST00000315580.5 ENST00000542099.1 ENST00000392435.2 ENST00000413381.2 ENST00000426960.2 ENST00000453766.2 |
ARL6IP4
|
ADP-ribosylation-like factor 6 interacting protein 4 |
| chr2_-_188419200 | 0.46 |
ENST00000233156.3
ENST00000426055.1 ENST00000453013.1 ENST00000417013.1 |
TFPI
|
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| chr11_-_75017734 | 0.46 |
ENST00000532525.1
|
ARRB1
|
arrestin, beta 1 |
| chr3_-_69062764 | 0.45 |
ENST00000295571.5
|
EOGT
|
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| chr12_-_108714412 | 0.45 |
ENST00000412676.1
ENST00000550573.1 |
CMKLR1
|
chemokine-like receptor 1 |
| chr14_-_75643296 | 0.45 |
ENST00000303575.4
|
TMED10
|
transmembrane emp24-like trafficking protein 10 (yeast) |
| chr19_+_41882598 | 0.45 |
ENST00000447302.2
ENST00000544232.1 ENST00000542945.1 ENST00000540732.1 |
TMEM91
CTC-435M10.3
|
transmembrane protein 91 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; Uncharacterized protein |
| chr9_-_95166841 | 0.43 |
ENST00000262551.4
|
OGN
|
osteoglycin |
| chr8_-_101719159 | 0.43 |
ENST00000520868.1
ENST00000522658.1 |
PABPC1
|
poly(A) binding protein, cytoplasmic 1 |
| chr17_+_26662597 | 0.42 |
ENST00000544907.2
|
TNFAIP1
|
tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| chr15_+_91411810 | 0.41 |
ENST00000268171.3
|
FURIN
|
furin (paired basic amino acid cleaving enzyme) |
| chr9_-_115819039 | 0.41 |
ENST00000555206.1
|
ZFP37
|
ZFP37 zinc finger protein |
| chr19_+_15751689 | 0.41 |
ENST00000586182.2
ENST00000591058.1 ENST00000221307.8 |
CYP4F3
|
cytochrome P450, family 4, subfamily F, polypeptide 3 |
| chr8_-_93029865 | 0.40 |
ENST00000422361.2
|
RUNX1T1
|
runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| chr16_-_58663720 | 0.39 |
ENST00000564557.1
ENST00000569240.1 ENST00000441024.2 ENST00000569020.1 ENST00000317147.5 |
CNOT1
|
CCR4-NOT transcription complex, subunit 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of NKX2-3
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 10.9 | 32.6 | GO:0006982 | response to lipid hydroperoxide(GO:0006982) |
| 2.0 | 10.0 | GO:0032487 | regulation of Rap protein signal transduction(GO:0032487) |
| 1.9 | 5.6 | GO:0002514 | B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663) |
| 1.4 | 4.2 | GO:0002752 | cell surface pattern recognition receptor signaling pathway(GO:0002752) |
| 1.1 | 5.3 | GO:0045906 | negative regulation of vasoconstriction(GO:0045906) |
| 1.0 | 7.8 | GO:1900623 | regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
| 0.9 | 17.0 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.9 | 2.8 | GO:2000532 | renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584) |
| 0.8 | 3.2 | GO:1904491 | protein localization to ciliary transition zone(GO:1904491) |
| 0.8 | 2.4 | GO:0070563 | negative regulation of vitamin D receptor signaling pathway(GO:0070563) |
| 0.8 | 2.3 | GO:1902994 | regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) |
| 0.7 | 2.9 | GO:0061304 | retinal blood vessel morphogenesis(GO:0061304) |
| 0.7 | 2.2 | GO:0007439 | ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611) |
| 0.7 | 2.8 | GO:0038195 | urokinase plasminogen activator signaling pathway(GO:0038195) |
| 0.7 | 4.2 | GO:2000323 | negative regulation of glucocorticoid receptor signaling pathway(GO:2000323) |
| 0.7 | 2.0 | GO:0009051 | pentose-phosphate shunt, oxidative branch(GO:0009051) |
| 0.6 | 5.8 | GO:0006069 | ethanol oxidation(GO:0006069) |
| 0.5 | 4.3 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 0.5 | 2.4 | GO:0033031 | positive regulation of neutrophil apoptotic process(GO:0033031) |
| 0.5 | 1.8 | GO:0003331 | regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) |
| 0.4 | 0.9 | GO:0014040 | positive regulation of Schwann cell differentiation(GO:0014040) |
| 0.4 | 4.9 | GO:0070129 | regulation of mitochondrial translation(GO:0070129) |
| 0.4 | 1.3 | GO:0006258 | UDP-glucose catabolic process(GO:0006258) |
| 0.4 | 1.6 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
| 0.4 | 1.9 | GO:0032747 | positive regulation of interleukin-23 production(GO:0032747) |
| 0.4 | 1.1 | GO:1900158 | negative regulation of osteoclast proliferation(GO:0090291) negative regulation of bone mineralization involved in bone maturation(GO:1900158) |
| 0.3 | 4.2 | GO:1901223 | negative regulation of NIK/NF-kappaB signaling(GO:1901223) |
| 0.3 | 1.5 | GO:0035524 | proline transmembrane transport(GO:0035524) |
| 0.3 | 0.9 | GO:0039506 | modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148) |
| 0.3 | 2.4 | GO:0015705 | iodide transport(GO:0015705) |
| 0.3 | 1.8 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.2 | 2.0 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
| 0.2 | 1.2 | GO:1902525 | regulation of protein monoubiquitination(GO:1902525) |
| 0.2 | 0.9 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
| 0.2 | 0.7 | GO:0036511 | trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512) |
| 0.2 | 2.0 | GO:1904684 | negative regulation of metalloendopeptidase activity(GO:1904684) |
| 0.2 | 1.3 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 0.2 | 0.8 | GO:0060335 | positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) |
| 0.2 | 2.3 | GO:0060174 | limb bud formation(GO:0060174) |
| 0.2 | 0.7 | GO:0090362 | positive regulation of platelet-derived growth factor production(GO:0090362) |
| 0.2 | 0.8 | GO:0051490 | negative regulation of filopodium assembly(GO:0051490) |
| 0.2 | 2.1 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
| 0.2 | 1.6 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.2 | 2.7 | GO:0010992 | ubiquitin homeostasis(GO:0010992) |
| 0.2 | 2.1 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
| 0.1 | 1.5 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
| 0.1 | 1.0 | GO:0097411 | hypoxia-inducible factor-1alpha signaling pathway(GO:0097411) |
| 0.1 | 3.5 | GO:0006590 | thyroid hormone generation(GO:0006590) |
| 0.1 | 0.4 | GO:0032900 | negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) negative regulation of neurotrophin production(GO:0032900) negative regulation of transforming growth factor beta1 production(GO:0032911) |
| 0.1 | 3.3 | GO:0032354 | response to follicle-stimulating hormone(GO:0032354) |
| 0.1 | 0.8 | GO:0015842 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) |
| 0.1 | 0.9 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 0.1 | 1.2 | GO:2000622 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.1 | 0.4 | GO:0001694 | histamine biosynthetic process(GO:0001694) |
| 0.1 | 1.2 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
| 0.1 | 1.8 | GO:2000480 | negative regulation of meiotic nuclear division(GO:0045835) negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.1 | 0.3 | GO:2001027 | negative regulation of endothelial cell chemotaxis(GO:2001027) |
| 0.1 | 0.4 | GO:0048205 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 0.1 | 0.9 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.1 | 0.7 | GO:1901529 | positive regulation of anion channel activity(GO:1901529) |
| 0.1 | 0.8 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
| 0.1 | 0.6 | GO:0046940 | nucleoside monophosphate phosphorylation(GO:0046940) |
| 0.1 | 0.3 | GO:0060369 | natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) |
| 0.1 | 1.3 | GO:0071670 | smooth muscle cell chemotaxis(GO:0071670) |
| 0.1 | 2.2 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
| 0.1 | 0.6 | GO:0060282 | positive regulation of oocyte development(GO:0060282) |
| 0.1 | 1.1 | GO:0046951 | ketone body biosynthetic process(GO:0046951) |
| 0.1 | 1.6 | GO:1990001 | inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001) |
| 0.1 | 1.2 | GO:0003376 | sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520) |
| 0.1 | 0.6 | GO:0016199 | axon midline choice point recognition(GO:0016199) |
| 0.1 | 0.3 | GO:0003219 | cardiac right ventricle formation(GO:0003219) |
| 0.1 | 1.0 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.1 | 2.7 | GO:0060334 | regulation of interferon-gamma-mediated signaling pathway(GO:0060334) |
| 0.1 | 0.4 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.1 | 0.8 | GO:0060088 | auditory receptor cell stereocilium organization(GO:0060088) |
| 0.1 | 2.9 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.1 | 1.2 | GO:2000291 | regulation of myoblast proliferation(GO:2000291) |
| 0.1 | 0.4 | GO:0036102 | leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569) |
| 0.1 | 0.6 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.1 | 2.3 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.1 | 0.9 | GO:0034372 | very-low-density lipoprotein particle remodeling(GO:0034372) |
| 0.1 | 0.9 | GO:0006346 | chromatin silencing at rDNA(GO:0000183) methylation-dependent chromatin silencing(GO:0006346) |
| 0.1 | 1.3 | GO:0016246 | RNA interference(GO:0016246) |
| 0.1 | 1.2 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.1 | 1.4 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) |
| 0.1 | 0.8 | GO:1901748 | leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750) |
| 0.1 | 0.4 | GO:0007598 | blood coagulation, extrinsic pathway(GO:0007598) |
| 0.1 | 2.6 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.1 | 0.9 | GO:0036315 | cellular response to sterol(GO:0036315) |
| 0.1 | 0.9 | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) |
| 0.0 | 0.5 | GO:0042492 | gamma-delta T cell differentiation(GO:0042492) |
| 0.0 | 0.5 | GO:0046498 | creatine metabolic process(GO:0006600) S-adenosylhomocysteine metabolic process(GO:0046498) |
| 0.0 | 1.1 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
| 0.0 | 1.1 | GO:1902236 | negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236) |
| 0.0 | 0.5 | GO:0042699 | follicle-stimulating hormone signaling pathway(GO:0042699) |
| 0.0 | 1.5 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 0.0 | 0.4 | GO:0070475 | rRNA base methylation(GO:0070475) |
| 0.0 | 1.9 | GO:0046850 | regulation of bone remodeling(GO:0046850) |
| 0.0 | 3.8 | GO:0060333 | interferon-gamma-mediated signaling pathway(GO:0060333) |
| 0.0 | 0.1 | GO:0038163 | thrombopoietin-mediated signaling pathway(GO:0038163) |
| 0.0 | 0.7 | GO:0034656 | nucleobase-containing small molecule catabolic process(GO:0034656) |
| 0.0 | 0.6 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.0 | 0.3 | GO:0086024 | adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) |
| 0.0 | 0.8 | GO:0010172 | embryonic body morphogenesis(GO:0010172) |
| 0.0 | 0.7 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.0 | 3.9 | GO:0090630 | activation of GTPase activity(GO:0090630) |
| 0.0 | 2.6 | GO:0002228 | natural killer cell mediated immunity(GO:0002228) |
| 0.0 | 0.9 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
| 0.0 | 0.5 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 0.0 | 0.4 | GO:0032695 | negative regulation of interleukin-12 production(GO:0032695) |
| 0.0 | 1.6 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.0 | 0.3 | GO:1900165 | negative regulation of interleukin-6 secretion(GO:1900165) |
| 0.0 | 0.7 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.0 | 0.5 | GO:0010002 | cardioblast differentiation(GO:0010002) |
| 0.0 | 0.2 | GO:0055059 | asymmetric neuroblast division(GO:0055059) |
| 0.0 | 0.3 | GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241) |
| 0.0 | 0.9 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 0.5 | GO:1902259 | regulation of delayed rectifier potassium channel activity(GO:1902259) |
| 0.0 | 0.6 | GO:0097503 | sialylation(GO:0097503) |
| 0.0 | 1.4 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
| 0.0 | 0.9 | GO:0010762 | regulation of fibroblast migration(GO:0010762) |
| 0.0 | 0.7 | GO:0050651 | dermatan sulfate proteoglycan biosynthetic process(GO:0050651) |
| 0.0 | 0.9 | GO:0071470 | cellular response to osmotic stress(GO:0071470) |
| 0.0 | 1.6 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.0 | 0.5 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.0 | 0.3 | GO:0046606 | negative regulation of centrosome cycle(GO:0046606) |
| 0.0 | 2.4 | GO:1902600 | hydrogen ion transmembrane transport(GO:1902600) |
| 0.0 | 0.4 | GO:0032098 | regulation of appetite(GO:0032098) |
| 0.0 | 1.4 | GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) |
| 0.0 | 0.1 | GO:0008343 | adult feeding behavior(GO:0008343) |
| 0.0 | 0.2 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.0 | 0.4 | GO:0071305 | cellular response to vitamin D(GO:0071305) |
| 0.0 | 0.4 | GO:0035728 | response to hepatocyte growth factor(GO:0035728) |
| 0.0 | 0.3 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.0 | 0.3 | GO:0071218 | cellular response to misfolded protein(GO:0071218) |
| 0.0 | 1.7 | GO:0007229 | integrin-mediated signaling pathway(GO:0007229) |
| 0.0 | 0.7 | GO:0042246 | tissue regeneration(GO:0042246) |
| 0.0 | 7.1 | GO:0043312 | neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312) |
| 0.0 | 0.6 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
| 0.0 | 0.4 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
| 0.0 | 1.0 | GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886) |
| 0.0 | 0.9 | GO:0060996 | dendritic spine development(GO:0060996) |
| 0.0 | 0.1 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.0 | 0.5 | GO:0006306 | DNA alkylation(GO:0006305) DNA methylation(GO:0006306) |
| 0.0 | 0.3 | GO:0032755 | positive regulation of interleukin-6 production(GO:0032755) |
| 0.0 | 0.2 | GO:0006705 | mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 7.8 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
| 0.8 | 2.3 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
| 0.7 | 4.2 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.6 | 5.6 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.5 | 2.2 | GO:1990745 | EARP complex(GO:1990745) |
| 0.5 | 1.5 | GO:1902636 | kinociliary basal body(GO:1902636) |
| 0.5 | 1.4 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 0.4 | 2.4 | GO:0002177 | manchette(GO:0002177) |
| 0.4 | 6.4 | GO:0045277 | respiratory chain complex IV(GO:0045277) |
| 0.3 | 3.5 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.3 | 2.8 | GO:0071438 | invadopodium membrane(GO:0071438) |
| 0.3 | 1.0 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
| 0.2 | 3.2 | GO:0036038 | MKS complex(GO:0036038) |
| 0.2 | 1.4 | GO:0036021 | endolysosome lumen(GO:0036021) |
| 0.2 | 3.8 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.2 | 1.1 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.2 | 16.8 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.1 | 1.6 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.1 | 10.0 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.1 | 0.8 | GO:0071203 | WASH complex(GO:0071203) |
| 0.1 | 1.6 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.1 | 1.3 | GO:0030478 | actin cap(GO:0030478) |
| 0.1 | 0.5 | GO:0034457 | Mpp10 complex(GO:0034457) |
| 0.1 | 1.8 | GO:0031588 | cAMP-dependent protein kinase complex(GO:0005952) nucleotide-activated protein kinase complex(GO:0031588) |
| 0.1 | 0.8 | GO:0070081 | clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083) |
| 0.1 | 1.3 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.1 | 1.0 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.1 | 1.2 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.1 | 0.9 | GO:0070578 | RISC-loading complex(GO:0070578) |
| 0.1 | 1.2 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.1 | 0.6 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.1 | 4.3 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.1 | 1.8 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.1 | 1.8 | GO:0090665 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.0 | 0.9 | GO:0097342 | ripoptosome(GO:0097342) |
| 0.0 | 2.8 | GO:0000313 | organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761) |
| 0.0 | 0.4 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.0 | 0.4 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 2.8 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 3.1 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.0 | 0.8 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.0 | 0.5 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.0 | 0.6 | GO:0032982 | myosin filament(GO:0032982) |
| 0.0 | 41.0 | GO:0005615 | extracellular space(GO:0005615) |
| 0.0 | 1.2 | GO:0000791 | euchromatin(GO:0000791) |
| 0.0 | 1.9 | GO:0036064 | ciliary basal body(GO:0036064) |
| 0.0 | 4.2 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 2.7 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 0.9 | GO:0045178 | basal part of cell(GO:0045178) |
| 0.0 | 0.9 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 1.1 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 8.9 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 0.2 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.0 | 1.2 | GO:0005770 | late endosome(GO:0005770) |
| 0.0 | 0.4 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 1.4 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 0.3 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 0.7 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 1.0 | GO:0000792 | heterochromatin(GO:0000792) |
| 0.0 | 1.6 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 0.3 | GO:0071565 | npBAF complex(GO:0071564) nBAF complex(GO:0071565) |
| 0.0 | 1.3 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.0 | 1.9 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.3 | 36.1 | GO:0008430 | selenium binding(GO:0008430) |
| 1.4 | 5.6 | GO:0005026 | transforming growth factor beta receptor activity, type II(GO:0005026) |
| 1.0 | 5.8 | GO:0004024 | alcohol dehydrogenase activity, zinc-dependent(GO:0004024) |
| 0.9 | 2.8 | GO:0030377 | urokinase plasminogen activator receptor activity(GO:0030377) |
| 0.9 | 4.3 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.8 | 3.9 | GO:0023024 | MHC class I protein complex binding(GO:0023024) |
| 0.8 | 2.3 | GO:0070326 | very-low-density lipoprotein particle receptor binding(GO:0070326) |
| 0.7 | 2.0 | GO:0017057 | 6-phosphogluconolactonase activity(GO:0017057) |
| 0.5 | 2.7 | GO:0004906 | interferon-gamma receptor activity(GO:0004906) |
| 0.5 | 2.1 | GO:0019862 | IgA binding(GO:0019862) |
| 0.5 | 6.9 | GO:0033691 | sialic acid binding(GO:0033691) |
| 0.5 | 12.0 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.4 | 2.0 | GO:0004883 | glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 0.4 | 1.9 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.4 | 1.2 | GO:0061629 | RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629) |
| 0.4 | 1.1 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 0.3 | 1.6 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.3 | 1.5 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
| 0.3 | 1.5 | GO:0002046 | opsin binding(GO:0002046) |
| 0.3 | 3.8 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 0.3 | 1.6 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 0.3 | 0.8 | GO:0015222 | serotonin transmembrane transporter activity(GO:0015222) |
| 0.3 | 1.0 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.2 | 7.2 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.2 | 1.7 | GO:0043533 | inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533) |
| 0.2 | 0.7 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
| 0.2 | 0.9 | GO:0004530 | deoxyribonuclease I activity(GO:0004530) |
| 0.2 | 0.9 | GO:0070568 | guanylyltransferase activity(GO:0070568) |
| 0.2 | 0.9 | GO:0097199 | cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199) |
| 0.2 | 2.7 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.2 | 2.9 | GO:0070330 | aromatase activity(GO:0070330) |
| 0.2 | 1.1 | GO:0016015 | morphogen activity(GO:0016015) |
| 0.2 | 0.6 | GO:0052798 | beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798) |
| 0.2 | 0.8 | GO:0090554 | phosphatidylcholine-translocating ATPase activity(GO:0090554) |
| 0.2 | 0.5 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
| 0.2 | 4.4 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.2 | 0.6 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
| 0.1 | 0.4 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
| 0.1 | 0.4 | GO:0052871 | tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259) |
| 0.1 | 0.1 | GO:0031782 | melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782) |
| 0.1 | 3.1 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.1 | 0.9 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.1 | 0.4 | GO:0016434 | rRNA (cytosine) methyltransferase activity(GO:0016434) |
| 0.1 | 0.9 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.1 | 1.2 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
| 0.1 | 1.6 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.1 | 0.9 | GO:0003696 | satellite DNA binding(GO:0003696) |
| 0.1 | 0.6 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 0.1 | 1.6 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.1 | 1.4 | GO:0030247 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.1 | 1.2 | GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
| 0.1 | 0.3 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
| 0.1 | 2.1 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.1 | 0.6 | GO:0050682 | AF-2 domain binding(GO:0050682) |
| 0.1 | 0.4 | GO:0001594 | trace-amine receptor activity(GO:0001594) |
| 0.1 | 1.6 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.1 | 0.3 | GO:0042954 | lipoprotein transporter activity(GO:0042954) |
| 0.1 | 4.2 | GO:0070888 | E-box binding(GO:0070888) |
| 0.1 | 1.8 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.1 | 1.9 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.1 | 0.3 | GO:0004909 | interleukin-1, Type I, activating receptor activity(GO:0004909) |
| 0.1 | 8.0 | GO:0005179 | hormone activity(GO:0005179) |
| 0.1 | 1.1 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.1 | 2.0 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 0.8 | GO:0032393 | MHC class I receptor activity(GO:0032393) |
| 0.1 | 1.4 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.1 | 0.7 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.1 | 0.8 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
| 0.1 | 1.0 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.1 | 0.9 | GO:0035256 | G-protein coupled glutamate receptor binding(GO:0035256) |
| 0.1 | 1.4 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
| 0.1 | 0.6 | GO:0004977 | melanocortin receptor activity(GO:0004977) |
| 0.1 | 0.6 | GO:0031432 | titin binding(GO:0031432) |
| 0.1 | 0.7 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.1 | 0.7 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.0 | 1.3 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.0 | 0.3 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.0 | 0.9 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.0 | 0.9 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.0 | 0.8 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.0 | 0.4 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.0 | 0.6 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.0 | 6.2 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.4 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.0 | 1.7 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 5.3 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 0.3 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
| 0.0 | 0.8 | GO:0050780 | dopamine receptor binding(GO:0050780) |
| 0.0 | 0.2 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 0.0 | 16.1 | GO:0003682 | chromatin binding(GO:0003682) |
| 0.0 | 1.0 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.0 | 3.5 | GO:0002020 | protease binding(GO:0002020) |
| 0.0 | 0.2 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.0 | 0.5 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.0 | 0.6 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
| 0.0 | 0.3 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.0 | 0.3 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 7.5 | GO:0004930 | G-protein coupled receptor activity(GO:0004930) |
| 0.0 | 0.7 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.0 | 1.3 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.0 | 0.2 | GO:0050998 | nitric-oxide synthase binding(GO:0050998) |
| 0.0 | 0.5 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 7.8 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.2 | 2.7 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
| 0.2 | 4.2 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.1 | 1.9 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.1 | 5.2 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.1 | 2.8 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.1 | 5.2 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 3.3 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.1 | 2.1 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.1 | 1.9 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.1 | 6.5 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.1 | 2.9 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.1 | 1.3 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.0 | 2.8 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.0 | 1.4 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 2.2 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.0 | 2.3 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 2.0 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.6 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 8.1 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 1.8 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 6.9 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 1.4 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.0 | 4.3 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 1.2 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.0 | 0.1 | PID S1P S1P2 PATHWAY | S1P2 pathway |
| 0.0 | 0.4 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 1.1 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.0 | 1.1 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 0.6 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 0.9 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 5.8 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.4 | 7.8 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.3 | 10.4 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.2 | 5.6 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.2 | 1.9 | REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES | Genes involved in p75NTR recruits signalling complexes |
| 0.1 | 3.3 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.1 | 3.5 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.1 | 3.2 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.1 | 3.1 | REACTOME ENDOGENOUS STEROLS | Genes involved in Endogenous sterols |
| 0.1 | 3.1 | REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
| 0.1 | 6.4 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.1 | 2.7 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.1 | 1.6 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.1 | 2.3 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.1 | 1.4 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.1 | 2.8 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.1 | 9.9 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.1 | 0.3 | REACTOME NUCLEAR SIGNALING BY ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.1 | 0.9 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.1 | 0.8 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.1 | 1.8 | REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION | Genes involved in Glucagon signaling in metabolic regulation |
| 0.1 | 1.3 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
| 0.1 | 1.0 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.1 | 0.9 | REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 | Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 |
| 0.1 | 1.4 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.1 | 0.7 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.0 | 1.3 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 4.2 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 7.8 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.0 | 0.9 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.0 | 2.8 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.0 | 1.1 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.0 | 1.2 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 0.9 | REACTOME MICRORNA MIRNA BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
| 0.0 | 0.6 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.0 | 2.4 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 1.6 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 0.6 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 0.4 | REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR | Genes involved in Signaling by constitutively active EGFR |
| 0.0 | 0.7 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.0 | 0.8 | REACTOME DOWNSTREAM TCR SIGNALING | Genes involved in Downstream TCR signaling |
| 0.0 | 1.4 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 1.3 | REACTOME G ALPHA S SIGNALLING EVENTS | Genes involved in G alpha (s) signalling events |
| 0.0 | 0.7 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.0 | 0.3 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 0.5 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |