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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for PAX4

Z-value: 0.90

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Transcription factors associated with PAX4

Gene Symbol Gene ID Gene Info
PAX4
ENSG00000106331.10 paired box 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX4hg19_v2_chr7_-_127255724_127255780-0.101.3e-01Click!

Activity profile of PAX4 motif

Sorted Z-values of PAX4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_32407619 30.34 ENST00000395388.2
ENST00000374982.5
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr4_-_84030996 27.88 ENST00000411416.2
PLAC8
placenta-specific 8
chr1_+_26644441 22.52 ENST00000374213.2
CD52
CD52 molecule
chr2_-_136875712 21.54 ENST00000241393.3
CXCR4
chemokine (C-X-C motif) receptor 4
chr6_+_32605195 21.53 ENST00000374949.2
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr7_+_80267973 19.17 ENST00000394788.3
ENST00000447544.2
CD36
CD36 molecule (thrombospondin receptor)
chr2_-_136873735 18.65 ENST00000409817.1
CXCR4
chemokine (C-X-C motif) receptor 4
chr6_+_31553901 16.02 ENST00000418507.2
ENST00000438075.2
ENST00000376100.3
ENST00000376111.4
LST1
leukocyte specific transcript 1
chr22_+_23229960 15.40 ENST00000526893.1
ENST00000532223.2
ENST00000531372.1
IGLL5
immunoglobulin lambda-like polypeptide 5
chr6_+_31553978 15.23 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
LST1
leukocyte specific transcript 1
chr6_+_32605134 13.54 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr1_-_153348067 13.07 ENST00000368737.3
S100A12
S100 calcium binding protein A12
chr11_+_1874200 12.24 ENST00000311604.3
LSP1
lymphocyte-specific protein 1
chr1_-_151032040 11.13 ENST00000540998.1
ENST00000357235.5
CDC42SE1
CDC42 small effector 1
chr18_-_53089723 10.72 ENST00000561992.1
ENST00000562512.2
TCF4
transcription factor 4
chr6_-_25042231 10.54 ENST00000510784.2
FAM65B
family with sequence similarity 65, member B
chr9_+_134103496 10.54 ENST00000498010.1
ENST00000476004.1
ENST00000528406.1
NUP214
nucleoporin 214kDa
chr1_-_25291475 9.82 ENST00000338888.3
ENST00000399916.1
RUNX3
runt-related transcription factor 3
chr19_+_55141861 9.28 ENST00000396327.3
ENST00000324602.7
ENST00000434867.2
LILRB1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr7_-_139763521 9.00 ENST00000263549.3
PARP12
poly (ADP-ribose) polymerase family, member 12
chr16_-_28621312 8.77 ENST00000314752.7
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr19_+_55141948 8.68 ENST00000396332.4
ENST00000427581.2
LILRB1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr17_+_47448102 8.36 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr6_+_31554456 8.23 ENST00000339530.4
LST1
leukocyte specific transcript 1
chr18_-_53255766 8.07 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr22_-_39151463 7.48 ENST00000405510.1
ENST00000433561.1
SUN2
Sad1 and UNC84 domain containing 2
chr8_+_41347915 7.38 ENST00000518270.1
ENST00000520817.1
GOLGA7
golgin A7
chr6_+_31554612 7.37 ENST00000211921.7
LST1
leukocyte specific transcript 1
chr19_-_54784937 7.26 ENST00000434421.1
ENST00000314446.5
ENST00000391749.4
LILRB2
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
chr6_-_90062543 7.24 ENST00000435041.2
UBE2J1
ubiquitin-conjugating enzyme E2, J1
chr16_+_69958887 7.02 ENST00000568684.1
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr17_+_43299241 6.98 ENST00000328118.3
FMNL1
formin-like 1
chr7_+_69064300 6.67 ENST00000342771.4
AUTS2
autism susceptibility candidate 2
chr16_-_28621298 6.67 ENST00000566189.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr6_+_15246501 6.56 ENST00000341776.2
JARID2
jumonji, AT rich interactive domain 2
chr16_-_28621353 6.50 ENST00000567512.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr11_-_93276582 6.41 ENST00000298966.2
SMCO4
single-pass membrane protein with coiled-coil domains 4
chr8_+_41348072 6.41 ENST00000405786.2
GOLGA7
golgin A7
chr1_-_1624083 6.41 ENST00000378662.1
ENST00000234800.6
SLC35E2B
solute carrier family 35, member E2B
chr1_+_101702417 6.33 ENST00000305352.6
S1PR1
sphingosine-1-phosphate receptor 1
chr9_-_20622478 6.00 ENST00000355930.6
ENST00000380338.4
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr7_-_137686791 5.87 ENST00000452463.1
ENST00000330387.6
ENST00000456390.1
CREB3L2
cAMP responsive element binding protein 3-like 2
chr8_-_145653885 5.49 ENST00000531032.1
ENST00000292510.4
ENST00000377348.2
ENST00000530790.1
ENST00000533806.1
VPS28
vacuolar protein sorting 28 homolog (S. cerevisiae)
chr7_-_37488834 5.49 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chrX_+_47004599 5.44 ENST00000329236.7
RBM10
RNA binding motif protein 10
chrX_+_47004639 5.10 ENST00000345781.6
RBM10
RNA binding motif protein 10
chr8_-_21771182 4.99 ENST00000523932.1
ENST00000544659.1
DOK2
docking protein 2, 56kDa
chr7_+_66386204 4.96 ENST00000341567.4
ENST00000607045.1
TMEM248
transmembrane protein 248
chr3_+_69134124 4.92 ENST00000478935.1
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr1_+_231376941 4.76 ENST00000436239.1
ENST00000366647.4
ENST00000366646.3
ENST00000416000.1
GNPAT
glyceronephosphate O-acyltransferase
chr8_-_21771214 4.74 ENST00000276420.4
DOK2
docking protein 2, 56kDa
chr3_-_197476560 4.69 ENST00000273582.5
KIAA0226
KIAA0226
chr4_+_47487285 4.62 ENST00000273859.3
ENST00000504445.1
ATP10D
ATPase, class V, type 10D
chr14_-_50053081 4.59 ENST00000396020.3
ENST00000245458.6
RPS29
ribosomal protein S29
chr19_+_14544099 4.02 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
PKN1
protein kinase N1
chr6_+_133135580 3.86 ENST00000230050.3
RPS12
ribosomal protein S12
chr22_-_31688431 3.68 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr10_+_114135004 3.39 ENST00000393081.1
ACSL5
acyl-CoA synthetase long-chain family member 5
chr6_+_31554636 3.23 ENST00000433492.1
LST1
leukocyte specific transcript 1
chr7_+_26331541 3.20 ENST00000416246.1
ENST00000338523.4
ENST00000412416.1
SNX10
sorting nexin 10
chr20_-_52210368 3.06 ENST00000371471.2
ZNF217
zinc finger protein 217
chr11_-_65374430 2.99 ENST00000532507.1
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr19_+_55105085 2.99 ENST00000251372.3
ENST00000453777.1
LILRA1
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
chr16_-_28608364 2.91 ENST00000533150.1
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr1_-_182360918 2.88 ENST00000339526.4
GLUL
glutamate-ammonia ligase
chr1_+_244816371 2.86 ENST00000263831.7
DESI2
desumoylating isopeptidase 2
chrX_+_135067576 2.80 ENST00000370701.1
ENST00000370698.3
ENST00000370695.4
SLC9A6
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
chr2_-_85839146 2.68 ENST00000306336.5
ENST00000409734.3
C2orf68
chromosome 2 open reading frame 68
chr11_-_67211263 2.62 ENST00000393893.1
CORO1B
coronin, actin binding protein, 1B
chr4_+_140586922 2.61 ENST00000265498.1
ENST00000506797.1
MGST2
microsomal glutathione S-transferase 2
chr1_-_182360498 2.37 ENST00000417584.2
GLUL
glutamate-ammonia ligase
chr7_+_100482595 2.33 ENST00000448764.1
SRRT
serrate RNA effector molecule homolog (Arabidopsis)
chr1_+_41157361 2.29 ENST00000427410.2
ENST00000447388.3
ENST00000425457.2
ENST00000453631.1
ENST00000456393.2
NFYC
nuclear transcription factor Y, gamma
chr8_+_21946681 2.22 ENST00000289921.7
FAM160B2
family with sequence similarity 160, member B2
chr17_+_33895090 2.17 ENST00000592381.1
RP11-1094M14.11
RP11-1094M14.11
chr1_+_12123414 2.10 ENST00000263932.2
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr5_-_133304473 2.03 ENST00000231512.3
C5orf15
chromosome 5 open reading frame 15
chr17_+_16284104 1.93 ENST00000577958.1
ENST00000302182.3
ENST00000577640.1
UBB
ubiquitin B
chr16_+_50730910 1.92 ENST00000300589.2
NOD2
nucleotide-binding oligomerization domain containing 2
chr17_+_16284399 1.85 ENST00000535788.1
UBB
ubiquitin B
chr2_-_20251744 1.85 ENST00000175091.4
LAPTM4A
lysosomal protein transmembrane 4 alpha
chr2_-_85555385 1.74 ENST00000377386.3
TGOLN2
trans-golgi network protein 2
chr9_-_123676827 1.63 ENST00000546084.1
TRAF1
TNF receptor-associated factor 1
chr4_+_492985 1.62 ENST00000296306.7
ENST00000536264.1
ENST00000310340.5
ENST00000453061.2
ENST00000504346.1
ENST00000503111.1
ENST00000383028.4
ENST00000509768.1
PIGG
phosphatidylinositol glycan anchor biosynthesis, class G
chr22_-_31688381 1.56 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr6_-_31697977 1.56 ENST00000375787.2
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr2_-_208489707 1.50 ENST00000448007.2
ENST00000432416.1
ENST00000411432.1
METTL21A
methyltransferase like 21A
chr3_+_39424828 1.49 ENST00000273158.4
ENST00000431510.1
SLC25A38
solute carrier family 25, member 38
chrX_-_131623874 1.46 ENST00000436215.1
MBNL3
muscleblind-like splicing regulator 3
chr1_-_208084729 1.45 ENST00000310833.7
ENST00000356522.4
CD34
CD34 molecule
chr2_-_191878162 1.40 ENST00000540176.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr19_-_49622348 1.36 ENST00000408991.2
C19orf73
chromosome 19 open reading frame 73
chr1_+_21880560 1.35 ENST00000425315.2
ALPL
alkaline phosphatase, liver/bone/kidney
chrX_+_65384182 1.35 ENST00000441993.2
ENST00000419594.1
HEPH
hephaestin
chr2_+_99797542 1.35 ENST00000338148.3
ENST00000512183.2
MRPL30
C2orf15
mitochondrial ribosomal protein L30
chromosome 2 open reading frame 15
chr5_-_130500922 1.34 ENST00000513012.1
ENST00000508488.1
ENST00000506908.1
ENST00000304043.5
HINT1
histidine triad nucleotide binding protein 1
chr2_+_12857043 1.31 ENST00000381465.2
TRIB2
tribbles pseudokinase 2
chr18_-_60987220 1.31 ENST00000398117.1
BCL2
B-cell CLL/lymphoma 2
chr20_-_44993012 1.29 ENST00000372229.1
ENST00000372230.5
ENST00000543605.1
ENST00000243896.2
ENST00000317734.8
SLC35C2
solute carrier family 35 (GDP-fucose transporter), member C2
chr8_+_11666649 1.28 ENST00000528643.1
ENST00000525777.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr2_-_87088995 1.28 ENST00000393759.2
ENST00000349455.3
ENST00000331469.2
ENST00000431506.2
ENST00000393761.2
ENST00000390655.6
CD8B
CD8b molecule
chr12_-_110888103 1.22 ENST00000426440.1
ENST00000228825.7
ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr5_-_142782862 1.19 ENST00000415690.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr13_-_46543805 1.19 ENST00000378921.2
ZC3H13
zinc finger CCCH-type containing 13
chr17_-_77005801 1.16 ENST00000392446.5
CANT1
calcium activated nucleotidase 1
chr11_+_72975559 1.14 ENST00000349767.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr11_+_20385327 1.11 ENST00000451739.2
ENST00000532505.1
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chrX_-_131623982 1.07 ENST00000370844.1
MBNL3
muscleblind-like splicing regulator 3
chr2_+_190526111 1.06 ENST00000607062.1
ENST00000260952.4
ENST00000425590.1
ENST00000607535.1
ENST00000420250.1
ENST00000606910.1
ENST00000607690.1
ENST00000607829.1
ASNSD1
asparagine synthetase domain containing 1
chr16_+_14980632 1.03 ENST00000565655.1
NOMO1
NODAL modulator 1
chr17_-_77005860 0.99 ENST00000591773.1
ENST00000588611.1
ENST00000586916.2
ENST00000592033.1
ENST00000588075.1
ENST00000302345.2
ENST00000591811.1
CANT1
calcium activated nucleotidase 1
chr16_-_28608424 0.98 ENST00000335715.4
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr10_+_6186847 0.96 ENST00000536985.1
ENST00000379789.4
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr11_-_59578202 0.95 ENST00000300151.4
MRPL16
mitochondrial ribosomal protein L16
chr11_+_72975524 0.95 ENST00000540342.1
ENST00000542092.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr8_-_101963677 0.93 ENST00000395956.3
ENST00000395953.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr11_+_72975578 0.90 ENST00000393592.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr1_+_41157421 0.89 ENST00000372654.1
NFYC
nuclear transcription factor Y, gamma
chr19_-_49955050 0.89 ENST00000262265.5
PIH1D1
PIH1 domain containing 1
chr9_-_100000957 0.86 ENST00000366109.2
ENST00000607322.1
RP11-498P14.5
RP11-498P14.5
chr18_+_29769978 0.80 ENST00000269202.6
ENST00000581447.1
MEP1B
meprin A, beta
chr9_+_130565487 0.78 ENST00000373225.3
ENST00000431857.1
FPGS
folylpolyglutamate synthase
chr5_-_93447333 0.77 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
FAM172A
family with sequence similarity 172, member A
chr8_-_101963482 0.77 ENST00000419477.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chrX_+_65384052 0.73 ENST00000336279.5
ENST00000458621.1
HEPH
hephaestin
chr12_+_100897130 0.71 ENST00000551379.1
ENST00000188403.7
ENST00000551184.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr1_+_33439268 0.67 ENST00000594612.1
FKSG48
FKSG48
chr19_-_52551814 0.66 ENST00000594154.1
ENST00000598745.1
ENST00000597273.1
ZNF432
zinc finger protein 432
chr9_+_123970052 0.65 ENST00000373823.3
GSN
gelsolin
chr21_+_43933946 0.64 ENST00000352133.2
SLC37A1
solute carrier family 37 (glucose-6-phosphate transporter), member 1
chr17_+_66521936 0.61 ENST00000592800.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr5_-_58882219 0.59 ENST00000505453.1
ENST00000360047.5
PDE4D
phosphodiesterase 4D, cAMP-specific
chr16_+_53088885 0.57 ENST00000566029.1
ENST00000447540.1
CHD9
chromodomain helicase DNA binding protein 9
chr6_-_32806506 0.57 ENST00000374897.2
ENST00000452392.2
TAP2
TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Uncharacterized protein
chr1_+_21877753 0.54 ENST00000374832.1
ALPL
alkaline phosphatase, liver/bone/kidney
chr3_-_123339343 0.50 ENST00000578202.1
MYLK
myosin light chain kinase
chr9_+_70971815 0.45 ENST00000396392.1
ENST00000396396.1
PGM5
phosphoglucomutase 5
chr17_-_42295870 0.45 ENST00000526094.1
ENST00000529383.1
ENST00000530828.1
UBTF
upstream binding transcription factor, RNA polymerase I
chr18_-_5396271 0.43 ENST00000579951.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr3_+_9975497 0.42 ENST00000397170.3
ENST00000383811.3
ENST00000452070.1
ENST00000326434.5
CRELD1
cysteine-rich with EGF-like domains 1
chr1_-_151319283 0.42 ENST00000392746.3
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr6_+_134274322 0.41 ENST00000367871.1
ENST00000237264.4
TBPL1
TBP-like 1
chr12_-_13248732 0.40 ENST00000396302.3
GSG1
germ cell associated 1
chr19_-_10420459 0.38 ENST00000403352.1
ENST00000403903.3
ZGLP1
zinc finger, GATA-like protein 1
chr19_-_4457776 0.37 ENST00000301281.6
UBXN6
UBX domain protein 6
chr12_-_113573495 0.35 ENST00000446861.3
RASAL1
RAS protein activator like 1 (GAP1 like)
chr12_-_13248705 0.29 ENST00000396310.2
GSG1
germ cell associated 1
chr11_+_118443098 0.29 ENST00000392859.3
ENST00000359415.4
ENST00000534182.2
ENST00000264028.4
ARCN1
archain 1
chr5_-_142783175 0.27 ENST00000231509.3
ENST00000394464.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr10_+_102295616 0.27 ENST00000299163.6
HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr7_-_22259845 0.26 ENST00000420196.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr7_+_72848092 0.23 ENST00000344575.3
FZD9
frizzled family receptor 9
chr17_-_26697304 0.21 ENST00000536498.1
VTN
vitronectin
chr18_+_29027696 0.20 ENST00000257189.4
DSG3
desmoglein 3
chr2_+_102972363 0.16 ENST00000409599.1
IL18R1
interleukin 18 receptor 1
chr4_-_169931393 0.16 ENST00000504480.1
ENST00000306193.3
CBR4
carbonyl reductase 4
chr10_-_71332994 0.13 ENST00000242462.4
NEUROG3
neurogenin 3
chr4_+_170541835 0.11 ENST00000504131.2
CLCN3
chloride channel, voltage-sensitive 3
chr5_-_32444828 0.09 ENST00000265069.8
ZFR
zinc finger RNA binding protein
chr7_-_96654133 0.07 ENST00000486603.2
ENST00000222598.4
DLX5
distal-less homeobox 5
chr2_+_203879568 0.05 ENST00000449802.1
NBEAL1
neurobeachin-like 1
chr8_-_134309335 0.03 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
NDRG1
N-myc downstream regulated 1

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
7.6 30.3 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
5.7 40.2 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
4.5 18.0 GO:2001191 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
2.8 13.8 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
2.7 19.2 GO:2000334 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
2.1 6.3 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
1.8 5.5 GO:0070086 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
1.8 7.3 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
1.7 5.2 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
1.7 6.7 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
1.6 4.8 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
1.5 27.9 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
1.3 5.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
1.2 7.5 GO:0031022 nuclear migration along microfilament(GO:0031022)
1.0 7.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
1.0 25.8 GO:0006068 ethanol catabolic process(GO:0006068)
0.9 2.6 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.7 2.1 GO:0032759 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.7 4.0 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.6 1.9 GO:0060584 detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.6 1.9 GO:0071529 cementum mineralization(GO:0071529)
0.6 3.8 GO:1902527 fat pad development(GO:0060613) positive regulation of protein monoubiquitination(GO:1902527)
0.6 4.9 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.6 22.5 GO:0045730 respiratory burst(GO:0045730)
0.6 6.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.6 2.8 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.5 6.0 GO:0007379 segment specification(GO:0007379) positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.5 48.0 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.4 3.0 GO:0007256 activation of JNKK activity(GO:0007256)
0.4 7.6 GO:0051014 actin filament severing(GO:0051014)
0.4 9.8 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.4 1.4 GO:0044467 glial cell-derived neurotrophic factor secretion(GO:0044467) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.3 1.4 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.3 11.9 GO:0050832 defense response to fungus(GO:0050832)
0.3 33.1 GO:0031295 T cell costimulation(GO:0031295)
0.3 0.9 GO:1903939 regulation of histone H3-K9 dimethylation(GO:1900109) negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.3 1.3 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.3 0.8 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.3 1.3 GO:0097384 cellular lipid biosynthetic process(GO:0097384)
0.2 15.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 0.7 GO:0090294 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.2 3.0 GO:0030321 transepithelial chloride transport(GO:0030321)
0.2 10.5 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.2 1.1 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.2 11.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.2 6.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.2 1.5 GO:0015816 glycine transport(GO:0015816)
0.2 1.5 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.2 10.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.2 1.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 7.0 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.2 3.2 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 3.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 2.3 GO:0031053 primary miRNA processing(GO:0031053)
0.1 1.3 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) protein O-linked fucosylation(GO:0036066)
0.1 2.6 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 1.7 GO:0090168 Golgi reassembly(GO:0090168)
0.1 3.2 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 0.4 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.4 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1 0.6 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 1.6 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 2.1 GO:0006825 copper ion transport(GO:0006825)
0.1 0.2 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of neuromuscular junction development(GO:1904397) bone regeneration(GO:1990523)
0.1 1.6 GO:0000052 citrulline metabolic process(GO:0000052)
0.1 1.7 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 0.6 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.4 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 3.7 GO:0006968 cellular defense response(GO:0006968)
0.1 3.2 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.1 0.5 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 13.4 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.4 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 6.6 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.5 GO:0019388 galactose catabolic process(GO:0019388)
0.0 1.2 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 3.7 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 2.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 2.1 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 1.3 GO:0050850 positive regulation of calcium-mediated signaling(GO:0050850)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.2 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 1.6 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.1 GO:0060290 transdifferentiation(GO:0060290)
0.0 5.6 GO:0007411 axon guidance(GO:0007411)
0.0 0.8 GO:1901998 toxin transport(GO:1901998)
0.0 0.4 GO:0003197 endocardial cushion development(GO:0003197)
0.0 0.2 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655)
0.0 0.2 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0 1.5 GO:0018022 peptidyl-lysine methylation(GO:0018022)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.5 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
3.1 65.4 GO:0042613 MHC class II protein complex(GO:0042613)
2.0 13.8 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.8 5.5 GO:0000813 ESCRT I complex(GO:0000813)
0.7 10.8 GO:0015629 actin cytoskeleton(GO:0015629)
0.6 18.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.6 7.5 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.6 2.8 GO:0044308 axonal spine(GO:0044308)
0.5 3.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.5 5.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 1.9 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.3 15.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.3 3.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.3 5.2 GO:0097386 glial cell projection(GO:0097386)
0.3 6.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 23.6 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 38.7 GO:0005770 late endosome(GO:0005770)
0.1 20.9 GO:0031225 anchored component of membrane(GO:0031225)
0.1 3.8 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 8.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.9 GO:0070761 pre-snoRNP complex(GO:0070761)
0.1 0.2 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 5.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 7.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.1 23.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 4.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 1.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 12.9 GO:0032993 protein-DNA complex(GO:0032993)
0.1 4.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.7 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 0.4 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 1.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 4.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.7 GO:0030478 actin cap(GO:0030478)
0.0 4.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 34.7 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.7 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.9 GO:0008180 COP9 signalosome(GO:0008180)
0.0 26.5 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.4 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.6 GO:0031588 cAMP-dependent protein kinase complex(GO:0005952) nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 8.4 GO:0016607 nuclear speck(GO:0016607)
0.0 5.9 GO:0000790 nuclear chromatin(GO:0000790)
0.0 6.2 GO:0034774 secretory granule lumen(GO:0034774)
0.0 5.5 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0030057 desmosome(GO:0030057)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 65.4 GO:0032395 MHC class II receptor activity(GO:0032395)
4.5 18.0 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
3.7 25.8 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
3.7 40.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
3.2 19.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
1.8 7.3 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
1.4 18.8 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.3 5.2 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
1.0 10.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.9 13.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.9 2.6 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.7 3.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.7 2.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.7 4.0 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.7 13.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.5 1.6 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.5 6.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036) sphingolipid binding(GO:0046625)
0.5 9.7 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.5 11.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.5 3.0 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.4 2.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.4 4.8 GO:0016413 palmitoyl-CoA hydrolase activity(GO:0016290) O-acetyltransferase activity(GO:0016413)
0.4 7.0 GO:0005522 profilin binding(GO:0005522)
0.4 7.5 GO:0043495 protein anchor(GO:0043495)
0.3 1.3 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.3 1.6 GO:0016403 dimethylargininase activity(GO:0016403)
0.3 1.5 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.3 9.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.3 15.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.3 2.8 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.3 5.7 GO:0035497 cAMP response element binding(GO:0035497)
0.3 1.9 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.2 1.5 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.2 0.7 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.2 2.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 1.1 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.2 0.6 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.2 2.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 6.6 GO:0032452 histone demethylase activity(GO:0032452)
0.2 1.3 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.2 3.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.2 4.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 5.2 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.2 1.9 GO:0042834 peptidoglycan binding(GO:0042834)
0.2 1.0 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.2 7.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 3.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.4 GO:0043199 sulfate binding(GO:0043199)
0.1 1.6 GO:0031996 thioesterase binding(GO:0031996)
0.1 1.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 3.2 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 0.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 4.8 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.7 GO:0045159 myosin II binding(GO:0045159)
0.1 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 1.4 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 29.1 GO:0003682 chromatin binding(GO:0003682)
0.0 5.5 GO:0043130 ubiquitin binding(GO:0043130)
0.0 1.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 1.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.0 8.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.6 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.8 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.6 GO:0008603 cAMP-dependent protein kinase inhibitor activity(GO:0004862) cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 1.3 GO:0005080 protein kinase C binding(GO:0005080)
0.0 3.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 3.0 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0004908 interleukin-1 receptor activity(GO:0004908)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 46.5 PID S1P S1P3 PATHWAY S1P3 pathway
0.6 30.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.4 10.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.3 13.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 4.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 11.6 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 15.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 5.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 3.0 PID IFNG PATHWAY IFN-gamma pathway
0.1 8.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 2.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.6 PID CD40 PATHWAY CD40/CD40L signaling
0.0 17.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 3.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.4 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.2 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
8.0 40.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
1.6 35.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.9 25.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.5 5.5 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.4 13.1 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.4 30.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.3 18.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.3 10.5 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.2 18.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 5.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 6.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.2 3.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 1.9 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.2 3.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.2 4.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 5.5 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 8.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 2.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 7.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 1.7 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 1.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 2.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 6.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.5 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors