Project

GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

Navigation
Downloads

Results for PBX1

Z-value: 0.85

Motif logo

Transcription factors associated with PBX1

Gene Symbol Gene ID Gene Info
ENSG00000185630.14 PBX homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PBX1hg19_v2_chr1_+_164529004_164529060-0.135.9e-02Click!

Activity profile of PBX1 motif

Sorted Z-values of PBX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_140135665 23.24 ENST00000340384.4
tubulin, beta 4B class IVb
chr4_+_83956237 14.04 ENST00000264389.2
COP9 signalosome subunit 4
chr4_+_83956312 14.00 ENST00000509317.1
ENST00000503682.1
ENST00000511653.1
COP9 signalosome subunit 4
chr18_+_29171689 12.57 ENST00000237014.3
transthyretin
chr8_+_98788003 11.57 ENST00000521545.2
lysosomal protein transmembrane 4 beta
chr10_-_101190202 8.94 ENST00000543866.1
ENST00000370508.5
glutamic-oxaloacetic transaminase 1, soluble
chr3_+_159557637 8.26 ENST00000445224.2
schwannomin interacting protein 1
chr4_+_69962185 8.00 ENST00000305231.7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr16_+_15596123 7.99 ENST00000452191.2
chromosome 16 open reading frame 45
chr4_+_69962212 7.66 ENST00000508661.1
UDP glucuronosyltransferase 2 family, polypeptide B7
chr12_+_20968608 7.22 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr12_+_79258444 7.06 ENST00000261205.4
synaptotagmin I
chr2_-_200323414 6.90 ENST00000443023.1
SATB homeobox 2
chr17_+_8191815 6.85 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RAN guanine nucleotide release factor
chr2_-_200322723 6.44 ENST00000417098.1
SATB homeobox 2
chr10_+_60028818 6.41 ENST00000333926.5
CDGSH iron sulfur domain 1
chr4_-_72649763 6.32 ENST00000513476.1
group-specific component (vitamin D binding protein)
chr14_+_50234309 6.28 ENST00000298307.5
kelch domain containing 2
chr2_-_10587897 6.21 ENST00000405333.1
ENST00000443218.1
ornithine decarboxylase 1
chr6_+_151561085 6.15 ENST00000402676.2
A kinase (PRKA) anchor protein 12
chrX_-_92928557 6.11 ENST00000373079.3
ENST00000475430.2
nucleosome assembly protein 1-like 3
chr8_-_91095099 6.01 ENST00000265431.3
calbindin 1, 28kDa
chr6_+_151561506 5.96 ENST00000253332.1
A kinase (PRKA) anchor protein 12
chr15_-_37393406 5.79 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
Meis homeobox 2
chr2_+_181845298 5.61 ENST00000410062.4
ubiquitin-conjugating enzyme E2E 3
chrX_+_119737806 5.55 ENST00000371317.5
malignant T cell amplified sequence 1
chr3_+_159570722 5.48 ENST00000482804.1
schwannomin interacting protein 1
chr12_+_79258547 5.37 ENST00000457153.2
synaptotagmin I
chr5_-_86708670 5.18 ENST00000504878.1
cyclin H
chr3_+_139063372 5.14 ENST00000478464.1
mitochondrial ribosomal protein S22
chr5_-_86708833 5.12 ENST00000256897.4
cyclin H
chr22_+_31795509 5.12 ENST00000331457.4
developmentally regulated GTP binding protein 1
chr12_+_21168630 5.03 ENST00000421593.2
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr7_-_7680601 4.96 ENST00000396682.2
replication protein A3, 14kDa
chr9_-_32573130 4.86 ENST00000350021.2
ENST00000379847.3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
chr9_-_101471479 4.72 ENST00000259455.2
gamma-aminobutyric acid (GABA) B receptor, 2
chr6_-_27114577 4.68 ENST00000356950.1
ENST00000396891.4
histone cluster 1, H2bk
chrM_+_4431 4.62 ENST00000361453.3
mitochondrially encoded NADH dehydrogenase 2
chr19_+_33072373 4.58 ENST00000586035.1
programmed cell death 5
chr2_-_96971232 4.55 ENST00000323853.5
small nuclear ribonucleoprotein 200kDa (U5)
chr1_-_28241024 4.49 ENST00000313433.7
ENST00000444045.1
replication protein A2, 32kDa
chr11_+_34938119 4.40 ENST00000227868.4
ENST00000430469.2
ENST00000533262.1
pyruvate dehydrogenase complex, component X
chr2_+_27886330 4.38 ENST00000326019.6
solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr10_+_48189612 4.32 ENST00000453919.1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 9
chr12_-_54653313 4.32 ENST00000550411.1
ENST00000439541.2
chromobox homolog 5
chr1_-_28241226 4.30 ENST00000373912.3
ENST00000373909.3
replication protein A2, 32kDa
chr8_-_101965559 4.09 ENST00000353245.3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr1_-_3713042 4.08 ENST00000378251.1
leucine rich repeat containing 47
chr2_-_88427568 4.04 ENST00000393750.3
ENST00000295834.3
fatty acid binding protein 1, liver
chr4_+_69681710 3.83 ENST00000265403.7
ENST00000458688.2
UDP glucuronosyltransferase 2 family, polypeptide B10
chr2_-_190044480 3.73 ENST00000374866.3
collagen, type V, alpha 2
chr20_+_44441271 3.68 ENST00000335046.3
ENST00000243893.6
ubiquitin-conjugating enzyme E2C
chr17_-_26694979 3.65 ENST00000438614.1
vitronectin
chr17_-_26695013 3.63 ENST00000555059.2
Homeobox protein SEBOX
chr13_-_46679185 3.62 ENST00000439329.3
carboxypeptidase B2 (plasma)
chr13_-_46679144 3.51 ENST00000181383.4
carboxypeptidase B2 (plasma)
chr10_+_114709999 3.42 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr15_-_64673630 3.38 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
chr21_-_35014027 3.35 ENST00000399442.1
ENST00000413017.2
ENST00000445393.1
ENST00000417979.1
ENST00000426935.1
ENST00000381540.3
ENST00000361534.2
ENST00000381554.3
crystallin, zeta (quinone reductase)-like 1
chrX_-_140673133 3.23 ENST00000370519.3
sperm protein associated with the nucleus, X-linked, family member A1
chr16_-_49890016 3.22 ENST00000563137.2
zinc finger protein 423
chrX_+_56590002 3.18 ENST00000338222.5
ubiquilin 2
chr5_+_162864575 3.16 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
cyclin G1
chr19_+_14640372 3.13 ENST00000215567.5
ENST00000598298.1
ENST00000596073.1
ENST00000600083.1
ENST00000436007.2
trans-2,3-enoyl-CoA reductase
chr12_-_102455846 3.10 ENST00000545679.1
coiled-coil domain containing 53
chr19_-_49955050 3.03 ENST00000262265.5
PIH1 domain containing 1
chr10_+_95517660 3.03 ENST00000371413.3
leucine-rich, glioma inactivated 1
chr17_+_72983674 2.99 ENST00000337231.5
cerebellar degeneration-related protein 2-like
chr14_-_74551096 2.95 ENST00000350259.4
aldehyde dehydrogenase 6 family, member A1
chr8_+_37887772 2.95 ENST00000338825.4
eukaryotic translation initiation factor 4E binding protein 1
chr2_-_27886460 2.94 ENST00000404798.2
ENST00000405491.1
ENST00000464789.2
ENST00000406540.1
suppressor of Ty 7 (S. cerevisiae)-like
chr10_+_95517566 2.93 ENST00000542308.1
leucine-rich, glioma inactivated 1
chr10_+_5488564 2.87 ENST00000449083.1
ENST00000380359.3
neuroepithelial cell transforming 1
chr16_-_70323422 2.83 ENST00000261772.8
alanyl-tRNA synthetase
chr2_+_219110149 2.81 ENST00000456575.1
actin related protein 2/3 complex, subunit 2, 34kDa
chr2_+_79412357 2.78 ENST00000466387.1
catenin (cadherin-associated protein), alpha 2
chr11_-_14380664 2.78 ENST00000545643.1
ENST00000256196.4
related RAS viral (r-ras) oncogene homolog 2
chr19_+_41770236 2.71 ENST00000392006.3
heterogeneous nuclear ribonucleoprotein U-like 1
chr4_-_70080449 2.71 ENST00000446444.1
UDP glucuronosyltransferase 2 family, polypeptide B11
chr9_+_106856831 2.70 ENST00000303219.8
ENST00000374787.3
structural maintenance of chromosomes 2
chr6_+_26199737 2.68 ENST00000359985.1
histone cluster 1, H2bf
chr3_+_179280668 2.54 ENST00000429709.2
ENST00000450518.2
ENST00000392662.1
ENST00000490364.1
actin-like 6A
chr10_+_95517616 2.51 ENST00000371418.4
leucine-rich, glioma inactivated 1
chr12_-_102455902 2.46 ENST00000240079.6
coiled-coil domain containing 53
chrX_-_70473957 2.42 ENST00000373984.3
ENST00000314425.5
ENST00000373982.1
zinc finger, MYM-type 3
chr1_-_54405773 2.40 ENST00000371376.1
heat shock protein family B (small), member 11
chr6_-_26124138 2.38 ENST00000314332.5
ENST00000396984.1
histone cluster 1, H2bc
chrX_-_63005405 2.35 ENST00000374878.1
ENST00000437457.2
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr12_-_76478686 2.35 ENST00000261182.8
nucleosome assembly protein 1-like 1
chr3_-_187388173 2.33 ENST00000287641.3
somatostatin
chr2_-_242626127 2.31 ENST00000445261.1
deoxythymidylate kinase (thymidylate kinase)
chr12_+_12870055 2.30 ENST00000228872.4
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chrX_-_70474499 2.29 ENST00000353904.2
zinc finger, MYM-type 3
chr2_+_264869 2.26 ENST00000272067.6
ENST00000272065.5
ENST00000407983.3
acid phosphatase 1, soluble
chr4_-_140005443 2.25 ENST00000510408.1
ENST00000420916.2
ENST00000358635.3
E74-like factor 2 (ets domain transcription factor)
chr11_-_118966167 2.23 ENST00000530167.1
H2A histone family, member X
chr16_+_69458537 2.19 ENST00000515314.1
ENST00000561792.1
ENST00000568237.1
cytochrome b5 type B (outer mitochondrial membrane)
chr11_+_44117260 2.10 ENST00000358681.4
exostosin glycosyltransferase 2
chr19_-_16008880 2.10 ENST00000011989.7
ENST00000221700.6
cytochrome P450, family 4, subfamily F, polypeptide 2
chrX_+_140677562 2.05 ENST00000370518.3
SPANX family, member A2
chr2_+_211342432 2.05 ENST00000430249.2
carbamoyl-phosphate synthase 1, mitochondrial
chr4_-_140005341 2.04 ENST00000379549.2
ENST00000512627.1
E74-like factor 2 (ets domain transcription factor)
chr11_-_34938039 2.01 ENST00000395787.3
APAF1 interacting protein
chr3_+_129159039 2.01 ENST00000507564.1
ENST00000431818.2
ENST00000504021.1
ENST00000349441.2
ENST00000348417.2
ENST00000440957.2
intraflagellar transport 122 homolog (Chlamydomonas)
chr5_-_10761206 2.00 ENST00000432074.2
ENST00000230895.6
death-associated protein
chr19_-_39881777 1.98 ENST00000595564.1
ENST00000221265.3
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr19_+_41770269 1.97 ENST00000378215.4
heterogeneous nuclear ribonucleoprotein U-like 1
chr16_+_16484691 1.91 ENST00000344087.4
nuclear pore complex interacting protein family, member A7
chr6_+_26124373 1.88 ENST00000377791.2
ENST00000602637.1
histone cluster 1, H2ac
chr14_-_60097297 1.87 ENST00000395090.1
reticulon 1
chr19_-_49121054 1.84 ENST00000546623.1
ENST00000084795.5
ribosomal protein L18
chr2_+_264913 1.84 ENST00000439645.2
ENST00000405233.1
acid phosphatase 1, soluble
chr22_-_39190116 1.79 ENST00000406622.1
ENST00000216068.4
ENST00000406199.3
Sad1 and UNC84 domain containing 2
dynein, axonemal, light chain 4
chr5_+_151151471 1.77 ENST00000394123.3
ENST00000543466.1
GTPase activating protein (SH3 domain) binding protein 1
chr11_+_44117099 1.75 ENST00000533608.1
exostosin glycosyltransferase 2
chr1_+_205473720 1.69 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
cyclin-dependent kinase 18
chr22_-_30642782 1.69 ENST00000249075.3
leukemia inhibitory factor
chr10_+_124320195 1.68 ENST00000359586.6
deleted in malignant brain tumors 1
chr10_+_18689637 1.67 ENST00000377315.4
calcium channel, voltage-dependent, beta 2 subunit
chr3_+_129158926 1.65 ENST00000347300.2
ENST00000296266.3
intraflagellar transport 122 homolog (Chlamydomonas)
chr11_+_844406 1.61 ENST00000397404.1
tetraspanin 4
chr2_+_234600253 1.61 ENST00000373424.1
ENST00000441351.1
UDP glucuronosyltransferase 1 family, polypeptide A6
chr8_-_101965146 1.54 ENST00000395957.2
ENST00000395948.2
ENST00000457309.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr17_+_21030260 1.51 ENST00000579303.1
dehydrogenase/reductase (SDR family) member 7B
chr2_+_12857015 1.41 ENST00000155926.4
tribbles pseudokinase 2
chr14_+_29236269 1.39 ENST00000313071.4
forkhead box G1
chr5_-_43313574 1.39 ENST00000325110.6
ENST00000433297.2
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr6_+_27114861 1.38 ENST00000377459.1
histone cluster 1, H2ah
chr5_+_65440032 1.35 ENST00000334121.6
splicing regulatory glutamine/lysine-rich protein 1
chr14_+_104182061 1.30 ENST00000216602.6
zinc finger, FYVE domain containing 21
chr5_+_140213815 1.30 ENST00000525929.1
ENST00000378125.3
protocadherin alpha 7
chrX_+_120181457 1.30 ENST00000328078.1
glutamate dehydrogenase 2
chr11_+_71903169 1.29 ENST00000393676.3
folate receptor 1 (adult)
chr5_-_125930929 1.29 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
aldehyde dehydrogenase 7 family, member A1
chr14_+_104182105 1.22 ENST00000311141.2
zinc finger, FYVE domain containing 21
chr5_+_43602750 1.17 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
nicotinamide nucleotide transhydrogenase
chr2_+_44396000 1.14 ENST00000409895.4
ENST00000409432.3
ENST00000282412.4
ENST00000378551.2
ENST00000345249.4
protein phosphatase, Mg2+/Mn2+ dependent, 1B
chr7_-_72971934 1.13 ENST00000411832.1
B-cell CLL/lymphoma 7B
chr3_+_122785895 1.12 ENST00000316218.7
protein disulfide isomerase family A, member 5
chr5_-_42825983 1.10 ENST00000506577.1
selenoprotein P, plasma, 1
chr9_-_6015607 1.09 ENST00000259569.5
RAN binding protein 6
chr6_-_167040731 1.08 ENST00000265678.4
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr4_+_37962018 1.05 ENST00000504686.1
pituitary tumor-transforming 2
chr22_-_30866564 0.98 ENST00000435069.1
ENST00000415957.2
ENST00000540910.1
SEC14-like 3 (S. cerevisiae)
chr17_+_73663402 0.97 ENST00000355423.3
SAP30 binding protein
chr8_-_95487331 0.97 ENST00000336148.5
RAD54 homolog B (S. cerevisiae)
chr11_+_31531291 0.93 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
elongator acetyltransferase complex subunit 4
chr11_+_66384053 0.89 ENST00000310137.4
ENST00000393979.3
ENST00000409372.1
ENST00000443702.1
ENST00000409738.4
ENST00000514361.3
ENST00000503028.2
ENST00000412278.2
ENST00000500635.2
RNA binding motif protein 14
RNA binding motif protein 4
RBM14-RBM4 readthrough
chr10_+_124320156 0.88 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
deleted in malignant brain tumors 1
chrX_-_6453159 0.86 ENST00000381089.3
ENST00000398729.1
variable charge, X-linked 3A
chr11_+_22689648 0.85 ENST00000278187.3
growth arrest-specific 2
chr17_+_45973516 0.84 ENST00000376741.4
Sp2 transcription factor
chr5_-_132073210 0.78 ENST00000378735.1
ENST00000378746.4
kinesin family member 3A
chr16_-_20364030 0.75 ENST00000396134.2
ENST00000573567.1
ENST00000570757.1
ENST00000424589.1
ENST00000302509.4
ENST00000571174.1
ENST00000576688.1
uromodulin
chr16_+_19222479 0.75 ENST00000568433.1
synaptotagmin XVII
chr3_-_160283348 0.74 ENST00000334256.4
karyopherin alpha 4 (importin alpha 3)
chr14_-_36789783 0.73 ENST00000605579.1
ENST00000604336.1
ENST00000359527.7
ENST00000603139.1
ENST00000318473.7
MAP3K12 binding inhibitory protein 1
chr5_+_151151504 0.68 ENST00000356245.3
ENST00000507878.2
GTPase activating protein (SH3 domain) binding protein 1
chr6_+_167704838 0.68 ENST00000366829.2
unc-93 homolog A (C. elegans)
chr4_-_69536346 0.67 ENST00000338206.5
UDP glucuronosyltransferase 2 family, polypeptide B15
chr17_+_73663470 0.66 ENST00000583536.1
SAP30 binding protein
chr4_-_73434498 0.65 ENST00000286657.4
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr14_-_74551172 0.63 ENST00000553458.1
aldehyde dehydrogenase 6 family, member A1
chr5_+_159656437 0.62 ENST00000402432.3
fatty acid binding protein 6, ileal
chrX_+_140084756 0.61 ENST00000449283.1
SPANX family, member B2
chr15_-_64673665 0.59 ENST00000300035.4
KIAA0101
chr12_-_57472522 0.56 ENST00000379391.3
ENST00000300128.4
transmembrane protein 194A
chr16_-_29499154 0.54 ENST00000354563.5
Uncharacterized protein
chrX_-_110655306 0.54 ENST00000371993.2
doublecortin
chr1_+_117602925 0.52 ENST00000369466.4
transcription termination factor, RNA polymerase II
chr3_+_148508845 0.50 ENST00000491148.1
carboxypeptidase B1 (tissue)
chr2_-_154335300 0.50 ENST00000325926.3
reprimo, TP53 dependent G2 arrest mediator candidate
chr5_-_132073111 0.49 ENST00000403231.1
kinesin family member 3A
chrX_-_102757802 0.48 ENST00000372633.1
RAB40A, member RAS oncogene family
chr10_+_5238793 0.47 ENST00000263126.1
aldo-keto reductase family 1, member C4
chr1_+_156589051 0.47 ENST00000255039.1
hyaluronan and proteoglycan link protein 2
chr19_-_3978083 0.47 ENST00000600794.1
eukaryotic translation elongation factor 2
chr15_+_44069276 0.47 ENST00000381359.1
small EDRK-rich factor 2
chr13_-_33760216 0.45 ENST00000255486.4
StAR-related lipid transfer (START) domain containing 13
chr12_+_21654714 0.45 ENST00000542038.1
ENST00000540141.1
ENST00000229314.5
golgi transport 1B
chr3_-_169587621 0.43 ENST00000523069.1
ENST00000316428.5
ENST00000264676.5
leucine rich repeat containing 31
chr16_-_20364122 0.39 ENST00000396138.4
ENST00000577168.1
uromodulin
chr19_-_14640005 0.39 ENST00000596853.1
ENST00000596075.1
ENST00000595992.1
ENST00000396969.4
ENST00000601533.1
ENST00000598692.1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr6_-_31782813 0.39 ENST00000375654.4
heat shock 70kDa protein 1-like
chr7_+_134331550 0.38 ENST00000344924.3
ENST00000418040.1
ENST00000393132.2
2,3-bisphosphoglycerate mutase
chr7_-_120498357 0.38 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
tetraspanin 12
chr14_-_107211459 0.35 ENST00000390636.2
immunoglobulin heavy variable 3-73
chr18_+_580367 0.32 ENST00000327228.3
centrin, EF-hand protein, 1
chr5_+_43603229 0.30 ENST00000344920.4
ENST00000512996.2
nicotinamide nucleotide transhydrogenase
chr11_-_34937858 0.27 ENST00000278359.5
APAF1 interacting protein
chr8_-_116681221 0.27 ENST00000395715.3
trichorhinophalangeal syndrome I
chr12_+_123944070 0.26 ENST00000412157.2
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr19_-_39881669 0.24 ENST00000221266.7
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr3_+_193853927 0.24 ENST00000232424.3
hes family bHLH transcription factor 1
chr4_+_120056939 0.23 ENST00000307128.5
myozenin 2
chr22_-_26961328 0.22 ENST00000398110.2
tyrosylprotein sulfotransferase 2
chr3_-_33481835 0.19 ENST00000283629.3
upstream binding protein 1 (LBP-1a)
chr19_+_58341656 0.17 ENST00000442832.4
ENST00000594901.1
zinc finger protein 587B
chr13_-_24895566 0.17 ENST00000422229.2
protein PCOTH isoform 1
chr4_-_105416039 0.14 ENST00000394767.2
CXXC finger protein 4

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.4 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
3.0 8.9 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
1.9 5.6 GO:0002188 translation reinitiation(GO:0002188)
1.8 7.1 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
1.8 28.0 GO:0000338 protein deneddylation(GO:0000338)
1.7 6.9 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
1.6 8.0 GO:1903976 negative regulation of glial cell migration(GO:1903976)
1.6 6.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
1.5 4.5 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
1.3 13.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
1.1 4.6 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
1.0 10.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
1.0 4.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
1.0 3.0 GO:1903939 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
1.0 12.6 GO:0070327 thyroid hormone transport(GO:0070327)
0.9 2.8 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.9 3.7 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.9 3.7 GO:0035720 signal transduction downstream of smoothened(GO:0007227) intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.9 3.6 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.8 3.2 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.8 11.7 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.8 17.9 GO:0052695 cellular glucuronidation(GO:0052695)
0.7 7.1 GO:0072221 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
0.7 2.1 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.6 2.3 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.6 2.3 GO:0009189 dTTP biosynthetic process(GO:0006235) deoxyribonucleoside diphosphate biosynthetic process(GO:0009189) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.6 3.4 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.5 4.4 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.5 13.8 GO:0070987 error-free translesion synthesis(GO:0070987)
0.5 3.7 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) positive regulation of exit from mitosis(GO:0031536)
0.4 1.3 GO:0060974 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
0.4 1.7 GO:0060708 histone H3-K27 acetylation(GO:0043974) leukemia inhibitory factor signaling pathway(GO:0048861) spongiotrophoblast differentiation(GO:0060708) regulation of histone H3-K27 acetylation(GO:1901674)
0.4 3.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.4 4.0 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.4 3.1 GO:0042761 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.4 3.9 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.4 5.6 GO:0090168 Golgi reassembly(GO:0090168)
0.4 7.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.4 0.7 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.3 12.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.3 2.0 GO:0034201 response to oleic acid(GO:0034201)
0.3 2.7 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.3 1.7 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.3 2.3 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.3 2.3 GO:0070269 pyroptosis(GO:0070269)
0.3 1.5 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.3 1.8 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.3 1.5 GO:0006740 NADPH regeneration(GO:0006740)
0.3 22.1 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.3 2.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.3 6.4 GO:0043457 regulation of cellular respiration(GO:0043457)
0.2 2.2 GO:0016584 nucleosome positioning(GO:0016584)
0.2 2.9 GO:0051451 myoblast migration(GO:0051451)
0.2 2.8 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.2 3.8 GO:0002192 IRES-dependent translational initiation(GO:0002192)
0.2 6.3 GO:0042359 vitamin D metabolic process(GO:0042359)
0.2 2.4 GO:0070986 left/right axis specification(GO:0070986)
0.2 1.1 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.2 1.3 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.2 1.3 GO:0042426 choline catabolic process(GO:0042426)
0.1 1.4 GO:0009642 response to light intensity(GO:0009642)
0.1 5.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 4.3 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.1 1.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 0.2 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 4.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.7 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 2.5 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 0.4 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.5 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 0.5 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 2.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 5.8 GO:0008542 visual learning(GO:0008542)
0.1 2.7 GO:0008210 estrogen metabolic process(GO:0008210)
0.1 0.2 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 1.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 5.1 GO:0070125 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.1 0.5 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 3.2 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 1.4 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.1 0.5 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 2.9 GO:0006458 'de novo' protein folding(GO:0006458)
0.1 1.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 8.5 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 5.5 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.7 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 2.4 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.8 GO:0035264 multicellular organism growth(GO:0035264)
0.0 4.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 3.2 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0 2.0 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 1.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.6 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 1.7 GO:0009988 cell-cell recognition(GO:0009988)
0.0 1.0 GO:0045143 homologous chromosome segregation(GO:0045143)
0.0 0.5 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.9 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 0.4 GO:0010842 retina layer formation(GO:0010842)
0.0 0.6 GO:1901661 quinone metabolic process(GO:1901661)
0.0 1.2 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 1.1 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.1 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.5 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 10.3 GO:0070985 TFIIK complex(GO:0070985)
2.5 12.4 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
1.6 4.7 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
1.2 3.7 GO:0005588 collagen type V trimer(GO:0005588)
1.0 3.9 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.9 2.8 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.9 13.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.9 3.6 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.6 3.7 GO:0030991 intraciliary transport particle A(GO:0030991)
0.6 3.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.5 28.4 GO:0008180 COP9 signalosome(GO:0008180)
0.5 4.0 GO:0045179 apical cortex(GO:0045179)
0.4 4.4 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.4 3.0 GO:0070761 pre-snoRNP complex(GO:0070761)
0.3 1.3 GO:0016939 kinesin II complex(GO:0016939)
0.3 4.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.3 2.7 GO:0000796 condensin complex(GO:0000796)
0.3 31.4 GO:0035578 azurophil granule lumen(GO:0035578)
0.2 2.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.2 2.5 GO:0030914 STAGA complex(GO:0030914)
0.2 2.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 5.1 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2 2.2 GO:0001673 male germ cell nucleus(GO:0001673) XY body(GO:0001741)
0.2 4.5 GO:0005682 U5 snRNP(GO:0005682)
0.2 13.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 2.6 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 1.8 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 1.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 3.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 2.5 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 2.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.9 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 14.9 GO:0043679 axon terminus(GO:0043679)
0.1 5.6 GO:0005844 polysome(GO:0005844)
0.1 6.9 GO:0014704 intercalated disc(GO:0014704)
0.1 1.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 4.3 GO:0000786 nucleosome(GO:0000786)
0.1 3.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 3.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.1 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 7.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 2.0 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 8.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 12.1 GO:0005938 cell cortex(GO:0005938)
0.0 3.2 GO:0005776 autophagosome(GO:0005776)
0.0 4.1 GO:0042383 sarcolemma(GO:0042383)
0.0 2.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.3 GO:0000243 commitment complex(GO:0000243)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 5.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 10.4 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 5.9 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.7 GO:0018995 host(GO:0018995) host cell(GO:0043657)
0.0 14.4 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 6.4 GO:0005925 focal adhesion(GO:0005925)
0.0 0.9 GO:0005884 actin filament(GO:0005884)
0.0 0.5 GO:0005811 lipid particle(GO:0005811)
0.0 6.9 GO:0045202 synapse(GO:0045202)
0.0 1.7 GO:0072562 blood microparticle(GO:0072562)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 8.9 GO:0070546 phosphatidylserine decarboxylase activity(GO:0004609) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
2.8 28.0 GO:0019784 NEDD8-specific protease activity(GO:0019784)
2.5 12.4 GO:0030348 syntaxin-3 binding(GO:0030348)
2.1 12.3 GO:0005499 vitamin D binding(GO:0005499)
1.6 4.7 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
1.3 4.0 GO:0010698 acetyltransferase activator activity(GO:0010698)
1.3 12.6 GO:0070324 thyroid hormone binding(GO:0070324)
1.0 4.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
1.0 6.9 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
1.0 3.9 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.9 2.8 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.8 8.8 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.8 3.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.8 12.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.7 24.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.7 2.1 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.7 23.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.7 2.0 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.6 1.3 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.6 12.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.6 4.0 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.6 3.3 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.5 4.4 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.4 3.0 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.4 10.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.4 2.5 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.4 2.3 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.3 1.3 GO:0061714 folic acid receptor activity(GO:0061714)
0.3 6.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.3 0.9 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.3 4.1 GO:0003993 acid phosphatase activity(GO:0003993) non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.3 1.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 0.7 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.2 3.6 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 1.7 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.2 9.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 2.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 5.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 3.4 GO:0070016 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.2 2.9 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 1.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 2.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 2.0 GO:0070513 death domain binding(GO:0070513)
0.1 4.9 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.1 3.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 1.8 GO:0043495 protein anchor(GO:0043495) dynein intermediate chain binding(GO:0045505)
0.1 1.5 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.4 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 4.3 GO:0005096 GTPase activator activity(GO:0005096)
0.1 5.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 2.5 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 7.2 GO:0003684 damaged DNA binding(GO:0003684)
0.1 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 4.3 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 1.1 GO:0019864 IgG binding(GO:0019864)
0.1 1.1 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 3.8 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 1.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 2.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 4.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0032052 bile acid binding(GO:0032052)
0.0 2.3 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.5 GO:0008097 5S rRNA binding(GO:0008097)
0.0 5.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 2.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 12.4 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.1 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 2.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.5 GO:0051287 NAD binding(GO:0051287)
0.0 4.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 3.8 GO:0044325 ion channel binding(GO:0044325)
0.0 1.1 GO:0030145 manganese ion binding(GO:0030145)
0.0 4.6 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 5.1 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 2.0 GO:0005179 hormone activity(GO:0005179)
0.0 0.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0031386 protein tag(GO:0031386)
0.0 4.1 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.2 14.4 PID ATR PATHWAY ATR signaling pathway
0.2 12.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.2 14.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 4.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 5.1 PID MYC PATHWAY C-MYC pathway
0.1 7.0 PID AURORA B PATHWAY Aurora B signaling
0.1 2.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.2 PID ATM PATHWAY ATM pathway
0.1 6.7 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.1 6.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 2.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 10.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 2.3 PID P53 REGULATION PATHWAY p53 pathway
0.0 3.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 2.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 2.3 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 1.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.4 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.2 PID ATF2 PATHWAY ATF-2 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 13.8 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.9 23.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.9 23.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.7 17.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.7 12.4 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.5 7.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.4 10.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.3 4.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 4.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 11.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.2 5.6 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.2 6.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 3.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.9 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 3.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 2.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 7.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 3.7 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 3.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 5.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 5.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 4.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 2.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 4.7 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 1.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.1 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 4.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 5.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 3.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives