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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for PBX3

Z-value: 1.20

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Transcription factors associated with PBX3

Gene Symbol Gene ID Gene Info
ENSG00000167081.12 PBX homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PBX3hg19_v2_chr9_+_128509624_128509658-0.171.4e-02Click!

Activity profile of PBX3 motif

Sorted Z-values of PBX3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_30032610 25.13 ENST00000574405.1
double C2-like domains, alpha
chr19_-_12662240 24.32 ENST00000416136.1
ENST00000428311.1
zinc finger protein 564
ZNF709
chr1_+_6845384 19.15 ENST00000303635.7
calmodulin binding transcription activator 1
chrX_+_103031758 18.80 ENST00000303958.2
ENST00000361621.2
proteolipid protein 1
chr19_-_12595586 18.68 ENST00000397732.3
zinc finger protein 709
chrX_+_103031421 18.38 ENST00000433491.1
ENST00000418604.1
ENST00000443502.1
proteolipid protein 1
chr16_-_53537105 18.27 ENST00000568596.1
ENST00000570004.1
ENST00000564497.1
ENST00000300245.4
ENST00000394657.7
AKT interacting protein
chr19_-_23578220 17.67 ENST00000595533.1
ENST00000397082.2
ENST00000599743.1
ENST00000300619.7
zinc finger protein 91
chr7_+_149571045 17.41 ENST00000479613.1
ENST00000606024.1
ENST00000464662.1
ENST00000425642.2
ATPase, H+ transporting V0 subunit e2
chr3_+_111717511 17.28 ENST00000478951.1
ENST00000393917.2
transgelin 3
chr3_+_111717600 17.21 ENST00000273368.4
transgelin 3
chr3_+_111718036 16.52 ENST00000455401.2
transgelin 3
chr3_+_111718173 16.23 ENST00000494932.1
transgelin 3
chr5_-_176057365 14.45 ENST00000310112.3
synuclein, beta
chr5_-_176057518 14.21 ENST00000393693.2
synuclein, beta
chr10_+_74451883 14.19 ENST00000373053.3
ENST00000357157.6
mitochondrial calcium uniporter
chr2_+_113033164 14.17 ENST00000409871.1
ENST00000343936.4
zinc finger CCCH-type containing 6
chr16_+_85061367 14.04 ENST00000538274.1
ENST00000258180.3
KIAA0513
chr4_-_89205879 12.90 ENST00000608933.1
ENST00000315194.4
ENST00000514204.1
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr9_+_74526384 12.29 ENST00000334731.2
ENST00000377031.3
chromosome 9 open reading frame 85
chr2_-_179672142 12.09 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
titin
chr15_+_25068773 11.97 ENST00000400100.1
ENST00000400098.1
small nuclear ribonucleoprotein polypeptide N
chr10_+_76586348 11.47 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
K(lysine) acetyltransferase 6B
chr19_-_42498369 10.83 ENST00000302102.5
ENST00000545399.1
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr19_-_42498231 10.59 ENST00000602133.1
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr19_+_2841433 10.42 ENST00000334241.4
ENST00000585966.1
ENST00000591539.1
zinc finger protein 555
chr19_-_21950362 10.24 ENST00000358296.6
zinc finger protein 100
chr19_-_14228541 10.15 ENST00000590853.1
ENST00000308677.4
protein kinase, cAMP-dependent, catalytic, alpha
chr4_+_175204818 10.14 ENST00000503780.1
centrosomal protein 44kDa
chr19_+_21579908 9.96 ENST00000596302.1
ENST00000392288.2
ENST00000594390.1
ENST00000355504.4
zinc finger protein 493
chr10_-_79789291 9.87 ENST00000372371.3
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chrX_+_102631248 9.47 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
nerve growth factor receptor (TNFRSF16) associated protein 1
chrX_-_100914781 9.43 ENST00000431597.1
ENST00000458024.1
ENST00000413506.1
ENST00000440675.1
ENST00000328766.5
ENST00000356824.4
armadillo repeat containing, X-linked 2
chr19_+_19976714 9.25 ENST00000589717.1
ENST00000355650.4
zinc finger protein 253
chr19_-_12267524 8.95 ENST00000455799.1
ENST00000355738.1
ENST00000439556.2
ENST00000542938.1
zinc finger protein 625
chr17_+_57232690 8.89 ENST00000262293.4
proline rich 11
chr6_+_36853607 8.74 ENST00000480824.2
ENST00000355190.3
ENST00000373685.1
chromosome 6 open reading frame 89
chr11_-_76155618 8.71 ENST00000530759.1
RP11-111M22.3
chr11_-_76155700 8.70 ENST00000572035.1
RP11-111M22.3
chr12_-_91573132 8.69 ENST00000550563.1
ENST00000546370.1
decorin
chr19_+_12035913 8.66 ENST00000591944.1
Uncharacterized protein; Zinc finger protein 763
chr12_-_91573249 8.61 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
decorin
chr19_+_2977444 8.40 ENST00000246112.4
ENST00000453329.1
ENST00000482627.1
ENST00000452088.1
transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
chr19_+_24097675 8.27 ENST00000525354.2
ENST00000334589.5
ENST00000531821.2
ENST00000594466.1
zinc finger protein 726
chr5_-_146302078 8.20 ENST00000508545.2
protein phosphatase 2, regulatory subunit B, beta
chr19_-_20748541 8.18 ENST00000427401.4
ENST00000594419.1
zinc finger protein 737
chr15_-_81282133 8.05 ENST00000261758.4
mesoderm development candidate 2
chr7_+_99699280 8.00 ENST00000421755.1
adaptor-related protein complex 4, mu 1 subunit
chr7_-_108166505 7.95 ENST00000426128.2
ENST00000427008.1
ENST00000388728.5
ENST00000257694.8
ENST00000422087.1
ENST00000453144.1
ENST00000436062.1
patatin-like phospholipase domain containing 8
chr12_-_121342170 7.87 ENST00000353487.2
signal peptide peptidase like 3
chr16_+_89238149 7.79 ENST00000289746.2
cadherin 15, type 1, M-cadherin (myotubule)
chr7_+_72742178 7.68 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FK506 binding protein 6, 36kDa
chr19_-_49140609 7.62 ENST00000601104.1
D site of albumin promoter (albumin D-box) binding protein
chrX_-_72434628 7.53 ENST00000536638.1
ENST00000373517.3
nucleosome assembly protein 1-like 2
chr19_+_21264980 7.44 ENST00000596053.1
ENST00000597086.1
ENST00000596143.1
ENST00000596367.1
ENST00000601416.1
zinc finger protein 714
chr7_+_99699179 7.16 ENST00000438383.1
ENST00000429084.1
ENST00000359593.4
ENST00000439416.1
adaptor-related protein complex 4, mu 1 subunit
chr2_+_20646824 7.14 ENST00000272233.4
ras homolog family member B
chr3_-_9885626 7.06 ENST00000424438.1
ENST00000433555.1
ENST00000427174.1
ENST00000418713.1
ENST00000433535.2
ENST00000383820.5
ENST00000433972.1
RNA pseudouridylate synthase domain containing 3
chr12_-_91573316 7.02 ENST00000393155.1
decorin
chr18_+_21693306 6.89 ENST00000540918.2
tetratricopeptide repeat domain 39C
chr6_-_169654139 6.88 ENST00000366787.3
thrombospondin 2
chr17_-_8066250 6.87 ENST00000488857.1
ENST00000481878.1
ENST00000316509.6
ENST00000498285.1
vesicle-associated membrane protein 2 (synaptobrevin 2)
Uncharacterized protein
chr19_-_23941639 6.86 ENST00000395385.3
ENST00000531570.1
ENST00000528059.1
zinc finger protein 681
chr7_+_110731062 6.85 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
leucine rich repeat neuronal 3
chr7_+_72742162 6.83 ENST00000431982.2
FK506 binding protein 6, 36kDa
chr7_+_64838712 6.82 ENST00000328747.7
ENST00000431504.1
ENST00000357512.2
zinc finger protein 92
chr16_+_23847267 6.78 ENST00000321728.7
protein kinase C, beta
chr12_+_57914742 6.77 ENST00000551351.1
methyl-CpG binding domain protein 6
chr19_+_44556158 6.68 ENST00000434772.3
ENST00000585552.1
zinc finger protein 223
chr19_-_12251202 6.61 ENST00000334213.5
zinc finger protein 20
chr19_+_21324827 6.58 ENST00000600692.1
ENST00000599296.1
ENST00000594425.1
ENST00000311048.7
zinc finger protein 431
chr19_-_12405606 6.56 ENST00000356109.5
zinc finger protein 44
chrX_+_53111541 6.38 ENST00000375442.4
ENST00000579390.1
TSPY-like 2
chr19_-_23433144 6.34 ENST00000418100.1
ENST00000597537.1
ENST00000597037.1
zinc finger protein 724, pseudogene
chr19_-_12476443 6.28 ENST00000242804.4
ENST00000438182.1
zinc finger protein 442
chr19_+_20959142 6.27 ENST00000344519.8
zinc finger protein 66
chr1_-_110283138 6.18 ENST00000256594.3
glutathione S-transferase mu 3 (brain)
chr4_+_6202448 6.08 ENST00000508601.1
RP11-586D19.1
chr16_+_1756162 6.07 ENST00000250894.4
ENST00000356010.5
mitogen-activated protein kinase 8 interacting protein 3
chr16_-_29479154 6.06 ENST00000549950.1
Uncharacterized protein
chr12_+_123717458 6.01 ENST00000253233.1
chromosome 12 open reading frame 65
chr7_+_64838786 5.90 ENST00000450302.2
zinc finger protein 92
chr10_-_102790852 5.89 ENST00000470414.1
ENST00000370215.3
PDZ domain containing 7
chr14_-_24584138 5.86 ENST00000558280.1
ENST00000561028.1
neural retina leucine zipper
chr12_-_16761007 5.77 ENST00000354662.1
ENST00000441439.2
LIM domain only 3 (rhombotin-like 2)
chr19_+_22235310 5.77 ENST00000600162.1
zinc finger protein 257
chr1_-_247267580 5.69 ENST00000366501.1
ENST00000366500.1
ENST00000476158.2
ENST00000448299.2
ENST00000358785.4
ENST00000343381.6
zinc finger protein 669
chr3_+_101498074 5.66 ENST00000273347.5
ENST00000474165.1
neurexophilin and PC-esterase domain family, member 3
chr1_+_150488205 5.54 ENST00000416894.1
long intergenic non-protein coding RNA 568
chr3_+_52489503 5.53 ENST00000345716.4
nischarin
chr7_-_44105158 5.51 ENST00000297283.3
phosphoglycerate mutase 2 (muscle)
chr19_+_50706866 5.42 ENST00000440075.2
ENST00000376970.2
ENST00000425460.1
ENST00000599920.1
ENST00000601313.1
myosin, heavy chain 14, non-muscle
chr6_-_32145861 5.40 ENST00000336984.6
1-acylglycerol-3-phosphate O-acyltransferase 1
chr13_+_52586517 5.36 ENST00000523764.1
ENST00000521508.1
ALG11, alpha-1,2-mannosyltransferase
chr22_-_39151947 5.32 ENST00000216064.4
Sad1 and UNC84 domain containing 2
chr10_+_104678102 5.30 ENST00000433628.2
cyclin M2
chr4_-_89205705 5.30 ENST00000295908.7
ENST00000510548.2
ENST00000508256.1
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr9_+_82186872 5.27 ENST00000376544.3
ENST00000376520.4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr14_-_91526922 5.21 ENST00000418736.2
ENST00000261991.3
ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr5_+_40909354 5.08 ENST00000313164.9
complement component 7
chr19_-_20844368 5.04 ENST00000595094.1
ENST00000601440.1
ENST00000291750.6
CTC-513N18.7
zinc finger protein 626
chr22_-_39151995 5.02 ENST00000405018.1
ENST00000438058.1
Sad1 and UNC84 domain containing 2
chr1_-_36235559 5.01 ENST00000251195.5
claspin
chr3_-_167813672 5.01 ENST00000470487.1
golgi integral membrane protein 4
chr8_+_105235572 4.99 ENST00000523362.1
regulating synaptic membrane exocytosis 2
chrX_+_100805496 4.98 ENST00000372829.3
armadillo repeat containing, X-linked 1
chr19_+_12175504 4.92 ENST00000439326.3
zinc finger protein 844
chr16_+_23847339 4.81 ENST00000303531.7
protein kinase C, beta
chr3_+_35681081 4.79 ENST00000428373.1
cAMP-regulated phosphoprotein, 21kDa
chr19_+_12075844 4.78 ENST00000592625.1
ENST00000586494.1
ENST00000343949.5
ENST00000545530.1
ENST00000358987.3
zinc finger protein 763
chr19_-_49140692 4.72 ENST00000222122.5
D site of albumin promoter (albumin D-box) binding protein
chr17_-_17875688 4.68 ENST00000379504.3
ENST00000318094.10
ENST00000540946.1
ENST00000542206.1
ENST00000395739.4
ENST00000581396.1
ENST00000535933.1
ENST00000579586.1
target of myb1-like 2 (chicken)
chr22_+_17082732 4.67 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
transmembrane phosphatase with tensin homology pseudogene 1
chr2_+_66662690 4.62 ENST00000488550.1
Meis homeobox 1
chr13_+_31191920 4.60 ENST00000255304.4
ubiquitin specific peptidase like 1
chr22_+_29469100 4.53 ENST00000327813.5
ENST00000407188.1
kringle containing transmembrane protein 1
chr19_+_22469210 4.51 ENST00000601693.1
zinc finger protein 729
chr14_+_76127529 4.48 ENST00000556977.1
ENST00000557636.1
ENST00000286650.5
ENST00000298832.9
tubulin tyrosine ligase-like family, member 5
chr4_+_6271558 4.44 ENST00000503569.1
ENST00000226760.1
Wolfram syndrome 1 (wolframin)
chr9_+_82186682 4.43 ENST00000376552.2
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chrX_-_139587225 4.41 ENST00000370536.2
SRY (sex determining region Y)-box 3
chr3_+_184279566 4.40 ENST00000330394.2
EPH receptor B3
chr12_-_57914275 4.34 ENST00000547303.1
ENST00000552740.1
ENST00000547526.1
ENST00000551116.1
ENST00000346473.3
DNA-damage-inducible transcript 3
chr22_-_39151463 4.33 ENST00000405510.1
ENST00000433561.1
Sad1 and UNC84 domain containing 2
chr14_+_24583836 4.30 ENST00000559115.1
ENST00000558215.1
ENST00000557810.1
ENST00000561375.1
ENST00000446197.3
ENST00000559796.1
ENST00000560713.1
ENST00000560901.1
ENST00000559382.1
DDB1 and CUL4 associated factor 11
chr2_-_176032843 4.30 ENST00000392544.1
ENST00000409499.1
ENST00000426833.3
ENST00000392543.2
ENST00000538946.1
ENST00000487334.2
ENST00000409833.1
ENST00000409635.1
ENST00000264110.2
ENST00000345739.5
activating transcription factor 2
chr13_-_41240717 4.28 ENST00000379561.5
forkhead box O1
chr1_-_110283660 4.28 ENST00000361066.2
glutathione S-transferase mu 3 (brain)
chr17_+_17876127 4.28 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
leucine rich repeat containing 48
chr19_+_55591743 4.27 ENST00000588359.1
ENST00000245618.5
EPS8-like 1
chr10_-_99531709 4.27 ENST00000266066.3
secreted frizzled-related protein 5
chr6_+_31620191 4.26 ENST00000375918.2
ENST00000375920.4
apolipoprotein M
chr17_-_73851285 4.25 ENST00000589642.1
ENST00000593002.1
ENST00000590221.1
ENST00000344296.4
ENST00000587374.1
ENST00000585462.1
ENST00000433525.2
ENST00000254806.3
WW domain binding protein 2
chr10_+_18429671 4.23 ENST00000282343.8
calcium channel, voltage-dependent, beta 2 subunit
chr11_-_73720276 4.23 ENST00000348534.4
uncoupling protein 3 (mitochondrial, proton carrier)
chr19_+_22817119 4.21 ENST00000456783.2
zinc finger protein 492
chr19_+_11998584 4.20 ENST00000429654.2
ENST00000445911.1
ENST00000340180.5
zinc finger protein 69
chr10_+_104678032 4.17 ENST00000369878.4
ENST00000369875.3
cyclin M2
chr2_-_88927092 4.16 ENST00000303236.3
eukaryotic translation initiation factor 2-alpha kinase 3
chr7_-_100183742 4.15 ENST00000310300.6
leucine-rich repeats and calponin homology (CH) domain containing 4
chr19_+_23299777 4.14 ENST00000597761.2
zinc finger protein 730
chr11_+_117014983 4.10 ENST00000527958.1
ENST00000419197.2
ENST00000304808.6
ENST00000529887.2
platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
chr19_+_22235279 4.07 ENST00000594363.1
ENST00000597927.1
ENST00000594947.1
zinc finger protein 257
chr17_-_44657017 4.07 ENST00000573185.1
ENST00000570550.1
ENST00000445552.2
ENST00000336125.5
ENST00000329240.4
ENST00000337845.7
ADP-ribosylation factor-like 17A
chr16_+_56642041 4.04 ENST00000245185.5
metallothionein 2A
chr9_-_35689900 4.04 ENST00000378300.5
ENST00000329305.2
ENST00000360958.2
tropomyosin 2 (beta)
chr19_+_22469236 3.99 ENST00000357491.6
zinc finger protein 729
chr6_+_110299501 3.94 ENST00000414000.2
G protein-coupled receptor 6
chr19_-_19843900 3.92 ENST00000344099.3
zinc finger protein 14
chr1_-_156470556 3.85 ENST00000489057.1
ENST00000348159.4
myocyte enhancer factor 2D
chr2_+_66662510 3.81 ENST00000272369.9
ENST00000407092.2
Meis homeobox 1
chrX_-_8700171 3.81 ENST00000262648.3
Kallmann syndrome 1 sequence
chr4_-_149363662 3.76 ENST00000355292.3
ENST00000358102.3
nuclear receptor subfamily 3, group C, member 2
chr3_-_3221358 3.74 ENST00000424814.1
ENST00000450014.1
ENST00000231948.4
ENST00000432408.2
cereblon
chr11_+_76156045 3.74 ENST00000533988.1
ENST00000524490.1
ENST00000334736.3
ENST00000343878.3
ENST00000533972.1
chromosome 11 open reading frame 30
chr16_-_89556942 3.74 ENST00000301030.4
ankyrin repeat domain 11
chr7_-_38370536 3.71 ENST00000390343.2
T cell receptor gamma variable 8
chr10_-_44144292 3.69 ENST00000374433.2
zinc finger protein 32
chr17_-_44439084 3.67 ENST00000575960.1
ENST00000575698.1
ENST00000571246.1
ENST00000434041.2
ENST00000570618.1
ENST00000450673.3
ADP-ribosylation factor-like 17B
chr19_-_12551849 3.67 ENST00000595562.1
ENST00000301547.5
Uncharacterized protein
zinc finger protein 443
chr4_+_47033607 3.64 ENST00000538619.1
gamma-aminobutyric acid (GABA) A receptor, beta 1
chr4_+_87515454 3.57 ENST00000427191.2
ENST00000436978.1
ENST00000502971.1
protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
chr8_+_38243821 3.57 ENST00000519476.2
leucine zipper-EF-hand containing transmembrane protein 2
chr19_+_11485333 3.56 ENST00000312423.2
SWIM-type zinc finger 7 associated protein 1
chr5_-_137514617 3.54 ENST00000254900.5
bromodomain containing 8
chr14_+_60975644 3.47 ENST00000327720.5
SIX homeobox 6
chr10_+_114710516 3.43 ENST00000542695.1
ENST00000346198.4
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr12_+_8975061 3.42 ENST00000299698.7
alpha-2-macroglobulin-like 1
chr7_+_100183927 3.37 ENST00000241071.6
ENST00000360609.2
F-box protein 24
chr17_-_44896047 3.37 ENST00000225512.5
wingless-type MMTV integration site family, member 3
chr17_+_46125707 3.31 ENST00000584137.1
ENST00000362042.3
ENST00000585291.1
ENST00000357480.5
nuclear factor, erythroid 2-like 1
chr9_-_119449483 3.28 ENST00000288520.5
ENST00000358637.4
ENST00000341734.4
astrotactin 2
chr19_+_20011775 3.27 ENST00000592245.1
ENST00000592160.1
ENST00000343769.5
AC007204.2
zinc finger protein 93
chr11_-_1593150 3.26 ENST00000397374.3
dual specificity phosphatase 8
chr11_+_112832202 3.26 ENST00000534015.1
neural cell adhesion molecule 1
chr22_-_37215523 3.24 ENST00000216200.5
parvalbumin
chrX_+_102883887 3.23 ENST00000372625.3
ENST00000372624.3
transcription elongation factor A (SII)-like 1
chr3_-_15382875 3.21 ENST00000408919.3
SH3-domain binding protein 5 (BTK-associated)
chr11_+_112832090 3.18 ENST00000533760.1
neural cell adhesion molecule 1
chr5_-_160975130 3.18 ENST00000274547.2
ENST00000520240.1
ENST00000517901.1
ENST00000353437.6
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr10_+_114710425 3.17 ENST00000352065.5
ENST00000369395.1
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr8_-_80680078 3.16 ENST00000337919.5
ENST00000354724.3
hes-related family bHLH transcription factor with YRPW motif 1
chr7_-_42276612 3.15 ENST00000395925.3
ENST00000437480.1
GLI family zinc finger 3
chr17_-_9929581 3.15 ENST00000437099.2
ENST00000396115.2
growth arrest-specific 7
chr19_+_19779619 3.15 ENST00000444249.2
ENST00000592502.1
zinc finger protein 101
chr3_-_186080012 3.14 ENST00000544847.1
ENST00000265022.3
diacylglycerol kinase, gamma 90kDa
chr16_+_67927147 3.13 ENST00000291041.5
protein serine kinase H1
chr11_-_4629388 3.10 ENST00000526337.1
ENST00000300747.5
tripartite motif containing 68
chr4_+_124317940 3.08 ENST00000505319.1
ENST00000339241.1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr19_+_58281014 3.08 ENST00000391702.3
ENST00000598885.1
ENST00000598183.1
ENST00000396154.2
ENST00000599802.1
ENST00000396150.4
zinc finger protein 586
chr14_-_82000140 3.05 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
sel-1 suppressor of lin-12-like (C. elegans)
chr19_-_22605136 3.00 ENST00000357774.5
ENST00000601553.1
ENST00000593657.1
zinc finger protein 98
chr22_-_41032668 2.97 ENST00000355630.3
ENST00000396617.3
ENST00000402042.1
megakaryoblastic leukemia (translocation) 1
chr17_-_1619491 2.96 ENST00000570416.1
ENST00000575626.1
ENST00000610106.1
ENST00000608198.1
ENST00000609442.1
ENST00000334146.3
ENST00000576489.1
ENST00000608245.1
ENST00000609398.1
ENST00000608913.1
ENST00000574016.1
ENST00000571091.1
ENST00000573127.1
ENST00000609990.1
ENST00000576749.1
MIR22 host gene (non-protein coding)
chr19_+_21265028 2.96 ENST00000291770.7
zinc finger protein 714
chr19_+_4969116 2.91 ENST00000588337.1
ENST00000159111.4
ENST00000381759.4
lysine (K)-specific demethylase 4B
chr19_-_57988871 2.88 ENST00000596831.1
ENST00000601768.1
ENST00000356584.3
ENST00000600175.1
ENST00000425074.3
ENST00000343280.4
ENST00000427512.2
Uncharacterized protein
zinc finger protein 772
chr12_+_58138800 2.88 ENST00000547992.1
ENST00000552816.1
ENST00000547472.1
tetraspanin 31
chr19_+_41284121 2.87 ENST00000594800.1
ENST00000357052.2
ENST00000602173.1
RAB4B, member RAS oncogene family
chr16_-_15187865 2.86 ENST00000327307.7
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 12.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
3.9 11.6 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
2.7 21.4 GO:0060075 regulation of resting membrane potential(GO:0060075)
2.4 14.7 GO:0031022 nuclear migration along microfilament(GO:0031022)
2.4 14.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
2.4 11.8 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
2.2 37.2 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
2.1 10.5 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
2.0 24.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
1.9 20.9 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
1.8 14.5 GO:0034587 piRNA metabolic process(GO:0034587)
1.5 5.9 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
1.4 7.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
1.4 8.4 GO:0070417 cellular response to cold(GO:0070417)
1.4 8.4 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
1.3 5.2 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
1.3 2.5 GO:0035995 detection of muscle stretch(GO:0035995)
1.2 2.5 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402) convergent extension involved in axis elongation(GO:0060028)
1.1 3.4 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339) Spemann organizer formation(GO:0060061)
1.1 4.3 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
1.1 4.3 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
1.1 3.2 GO:0060364 frontal suture morphogenesis(GO:0060364)
1.0 5.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
1.0 3.1 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
1.0 5.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
1.0 3.0 GO:0090076 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) relaxation of skeletal muscle(GO:0090076)
1.0 7.9 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
1.0 5.8 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.8 10.1 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.8 5.9 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.8 3.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.8 2.5 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.8 1.6 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.8 4.0 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.8 3.2 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.8 2.3 GO:0021592 fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
0.7 4.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.7 11.8 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.7 30.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.7 4.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.7 4.8 GO:0072592 oxygen metabolic process(GO:0072592)
0.7 8.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.7 5.4 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.6 15.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.6 2.4 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.6 17.4 GO:0007035 vacuolar acidification(GO:0007035)
0.6 4.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.6 4.6 GO:0016926 protein desumoylation(GO:0016926)
0.6 18.2 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.6 7.9 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.6 6.7 GO:0022417 protein maturation by protein folding(GO:0022417)
0.5 21.2 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.5 6.5 GO:0007512 adult heart development(GO:0007512)
0.5 3.0 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.5 28.5 GO:0042417 dopamine metabolic process(GO:0042417)
0.5 9.6 GO:0034776 response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.5 1.9 GO:2001054 regulation of mesenchymal cell apoptotic process(GO:2001053) negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.5 3.3 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.5 1.4 GO:0072560 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.5 3.7 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.5 1.4 GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585) positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.5 2.8 GO:0071910 determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910)
0.5 1.8 GO:0042377 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.4 2.6 GO:0021764 amygdala development(GO:0021764)
0.4 4.3 GO:0009414 response to water deprivation(GO:0009414)
0.4 4.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.4 2.9 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.4 1.7 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.4 2.9 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.4 7.2 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.4 4.6 GO:0090520 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.4 3.7 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.4 1.5 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.4 0.7 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.4 8.0 GO:0015874 norepinephrine transport(GO:0015874)
0.4 7.3 GO:0035855 megakaryocyte development(GO:0035855)
0.4 5.4 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.4 1.1 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.3 1.4 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.3 1.4 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.3 1.7 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.3 1.3 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.3 2.0 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.3 1.0 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.3 2.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.3 13.4 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.3 2.8 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.3 6.7 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.3 19.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.3 5.1 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.3 2.6 GO:0055072 iron ion homeostasis(GO:0055072)
0.3 5.4 GO:0071625 vocalization behavior(GO:0071625)
0.3 1.5 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.2 4.7 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.2 2.3 GO:0007638 mechanosensory behavior(GO:0007638)
0.2 4.4 GO:1990845 adaptive thermogenesis(GO:1990845)
0.2 0.7 GO:0030497 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.2 2.0 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.2 1.2 GO:0070166 enamel mineralization(GO:0070166)
0.2 1.0 GO:0071313 cellular response to caffeine(GO:0071313)
0.2 4.3 GO:0006590 thyroid hormone generation(GO:0006590)
0.2 1.3 GO:0070995 NADPH oxidation(GO:0070995)
0.2 2.7 GO:0006768 biotin metabolic process(GO:0006768)
0.2 0.9 GO:0035524 proline transmembrane transport(GO:0035524)
0.2 0.9 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.2 3.8 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.2 3.5 GO:0060325 face morphogenesis(GO:0060325)
0.2 0.5 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.2 1.5 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.2 0.7 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.2 13.7 GO:0043966 histone H3 acetylation(GO:0043966)
0.2 0.8 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.2 0.6 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.2 4.0 GO:0021854 hypothalamus development(GO:0021854)
0.1 0.7 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.1 4.9 GO:0042572 retinol metabolic process(GO:0042572)
0.1 6.1 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.1 0.9 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.1 9.8 GO:0007050 cell cycle arrest(GO:0007050)
0.1 1.3 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.1 2.6 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.1 0.4 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 2.4 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 2.0 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 1.4 GO:0090312 positive regulation of protein deacetylation(GO:0090312)
0.1 3.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 3.2 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 2.3 GO:0006921 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.1 3.3 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 3.0 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 0.8 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.1 1.7 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.1 0.7 GO:0006824 cobalt ion transport(GO:0006824)
0.1 5.4 GO:1903146 regulation of mitophagy(GO:1903146)
0.1 1.0 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 4.1 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.1 0.5 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.1 3.1 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.1 8.8 GO:0006415 translational termination(GO:0006415)
0.1 1.4 GO:1902083 cellular response to hydroperoxide(GO:0071447) negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 2.4 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 0.8 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 2.7 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 5.1 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.2 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 2.8 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.1 0.6 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.1 1.2 GO:0060322 head development(GO:0060322)
0.1 2.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 2.1 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 0.6 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.6 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 5.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 1.2 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 6.0 GO:0060173 appendage development(GO:0048736) limb development(GO:0060173)
0.1 2.2 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.1 7.4 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.1 2.5 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 3.1 GO:0016579 protein deubiquitination(GO:0016579)
0.1 1.8 GO:0046710 GDP metabolic process(GO:0046710)
0.1 6.4 GO:0007498 mesoderm development(GO:0007498)
0.1 7.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.8 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.1 GO:0048867 stem cell fate determination(GO:0048867)
0.0 2.8 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 2.4 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.4 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.2 GO:0044108 cellular alcohol metabolic process(GO:0044107) cellular alcohol biosynthetic process(GO:0044108)
0.0 4.3 GO:0006334 nucleosome assembly(GO:0006334)
0.0 1.6 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 3.2 GO:0046323 glucose import(GO:0046323)
0.0 0.3 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.2 GO:2000678 negative regulation of transcription regulatory region DNA binding(GO:2000678)
0.0 0.7 GO:0050901 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0 2.5 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.0 24.9 GO:0007417 central nervous system development(GO:0007417)
0.0 0.4 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 1.4 GO:0006301 postreplication repair(GO:0006301)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 1.7 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 2.1 GO:0000724 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 1.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.7 GO:0010107 potassium ion import(GO:0010107)
0.0 1.1 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
0.0 3.5 GO:0007601 visual perception(GO:0007601) sensory perception of light stimulus(GO:0050953)
0.0 2.4 GO:0061572 actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.0 1.6 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 2.9 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 2.7 GO:0007411 axon guidance(GO:0007411)
0.0 1.5 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 0.7 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.3 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.3 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.6 GO:0071260 cellular response to mechanical stimulus(GO:0071260)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 20.1 GO:0070695 FHF complex(GO:0070695)
3.5 14.2 GO:1990246 uniplex complex(GO:1990246)
3.1 21.4 GO:0044326 dendritic spine neck(GO:0044326)
2.5 15.2 GO:0000138 Golgi trans cisterna(GO:0000138)
2.0 5.9 GO:0002139 stereocilia coupling link(GO:0002139)
1.7 24.3 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.7 6.9 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
1.4 4.3 GO:1990622 CHOP-ATF3 complex(GO:1990622)
1.4 4.3 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
1.2 17.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
1.1 11.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
1.1 14.7 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
1.1 7.9 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
1.1 3.3 GO:0060187 cell pole(GO:0060187)
1.0 11.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.7 12.0 GO:0005687 U4 snRNP(GO:0005687)
0.6 3.0 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.6 2.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.6 5.1 GO:0005579 membrane attack complex(GO:0005579)
0.6 10.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.5 1.6 GO:0060076 excitatory synapse(GO:0060076)
0.5 4.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.4 0.8 GO:0098798 mitochondrial protein complex(GO:0098798)
0.4 4.6 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.4 1.5 GO:0030314 junctional membrane complex(GO:0030314)
0.4 2.9 GO:0032593 insulin-responsive compartment(GO:0032593)
0.3 1.3 GO:1990031 pinceau fiber(GO:1990031)
0.3 4.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.3 6.8 GO:0010369 chromocenter(GO:0010369)
0.3 0.9 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.3 3.4 GO:1990909 Wnt signalosome(GO:1990909)
0.3 77.5 GO:0043209 myelin sheath(GO:0043209)
0.3 9.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.3 2.3 GO:0033270 paranode region of axon(GO:0033270)
0.2 2.0 GO:0005610 laminin-5 complex(GO:0005610)
0.2 10.1 GO:0030496 midbody(GO:0030496)
0.2 8.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 1.0 GO:0035838 growing cell tip(GO:0035838)
0.2 2.6 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 1.2 GO:0044308 axonal spine(GO:0044308)
0.2 4.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.2 5.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 2.8 GO:0036038 MKS complex(GO:0036038)
0.2 4.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2 3.0 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.2 20.1 GO:0016234 inclusion body(GO:0016234)
0.2 13.6 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 2.4 GO:0035869 ciliary transition zone(GO:0035869)
0.2 2.3 GO:0000124 SAGA complex(GO:0000124)
0.2 6.0 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 5.0 GO:0005859 muscle myosin complex(GO:0005859)
0.1 5.0 GO:0048786 presynaptic active zone(GO:0048786)
0.1 6.8 GO:0005801 cis-Golgi network(GO:0005801)
0.1 9.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 2.9 GO:0035861 site of double-strand break(GO:0035861)
0.1 2.0 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 1.7 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 3.2 GO:0016592 mediator complex(GO:0016592)
0.1 0.6 GO:0098827 terminal cisterna(GO:0014802) endoplasmic reticulum subcompartment(GO:0098827)
0.1 2.9 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 6.1 GO:0000139 Golgi membrane(GO:0000139)
0.1 0.6 GO:0036157 outer dynein arm(GO:0036157)
0.1 3.9 GO:0042734 presynaptic membrane(GO:0042734)
0.1 1.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 7.2 GO:0005604 basement membrane(GO:0005604)
0.1 4.3 GO:0032587 ruffle membrane(GO:0032587)
0.1 1.5 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 3.2 GO:0043195 terminal bouton(GO:0043195)
0.0 1.7 GO:0043679 axon terminus(GO:0043679)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 5.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.4 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.7 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 1.9 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.6 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 2.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 4.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.0 GO:0000502 proteasome complex(GO:0000502)
0.0 9.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.3 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 4.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.7 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.7 GO:0005657 replication fork(GO:0005657)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 11.6 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
2.9 34.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
2.0 28.7 GO:1903136 cuprous ion binding(GO:1903136)
2.0 6.0 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
2.0 7.9 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
1.8 5.4 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
1.5 21.4 GO:1990239 steroid hormone binding(GO:1990239)
1.4 4.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
1.3 5.0 GO:0010997 anaphase-promoting complex binding(GO:0010997)
1.2 12.1 GO:0031433 telethonin binding(GO:0031433)
1.0 1.0 GO:0016774 phosphoglycerate kinase activity(GO:0004618) phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
1.0 2.9 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.9 4.5 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.9 2.7 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.9 7.9 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.8 5.9 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.8 3.3 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.8 2.5 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
0.8 4.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.8 4.8 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.8 3.2 GO:0035939 microsatellite binding(GO:0035939)
0.8 7.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.7 13.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.7 4.3 GO:0004447 iodide peroxidase activity(GO:0004447)
0.7 6.4 GO:0000182 rDNA binding(GO:0000182)
0.7 9.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.7 2.7 GO:0047708 biotinidase activity(GO:0047708)
0.6 2.6 GO:0052812 phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.6 10.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.6 17.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.6 6.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.6 15.1 GO:0005521 lamin binding(GO:0005521)
0.6 4.6 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.6 1.7 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.5 4.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.5 6.4 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.5 4.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.5 3.3 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.5 3.7 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.5 3.2 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.4 8.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.4 29.6 GO:0030276 clathrin binding(GO:0030276)
0.4 4.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.4 1.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.4 2.9 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.3 1.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.3 1.7 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.3 2.7 GO:0005497 androgen binding(GO:0005497)
0.3 4.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 4.3 GO:0042608 T cell receptor binding(GO:0042608)
0.3 2.5 GO:0071253 connexin binding(GO:0071253)
0.3 4.0 GO:0046870 cadmium ion binding(GO:0046870)
0.3 22.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.3 6.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 2.8 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.3 1.0 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.2 5.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 1.0 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.2 2.8 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.2 5.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.2 2.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.2 4.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 6.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 3.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 1.5 GO:0004126 cytidine deaminase activity(GO:0004126)
0.2 10.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 2.8 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.2 1.4 GO:0048156 tau protein binding(GO:0048156)
0.2 13.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.2 45.9 GO:0051015 actin filament binding(GO:0051015)
0.2 26.6 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.2 2.4 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.2 0.9 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.2 2.0 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 3.4 GO:0048018 receptor agonist activity(GO:0048018)
0.2 4.0 GO:0005003 ephrin receptor activity(GO:0005003)
0.2 15.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.2 1.7 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 0.7 GO:0031419 cobalamin binding(GO:0031419)
0.2 0.5 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.2 0.7 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.2 4.1 GO:0004806 triglyceride lipase activity(GO:0004806)
0.2 5.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 1.9 GO:0003680 AT DNA binding(GO:0003680)
0.2 1.4 GO:0034452 dynactin binding(GO:0034452)
0.2 4.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 4.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 2.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 9.5 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 1.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 2.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 14.2 GO:0005262 calcium channel activity(GO:0005262)
0.1 1.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 2.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 1.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 3.0 GO:0016805 dipeptidase activity(GO:0016805)
0.1 13.7 GO:0061630 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.1 1.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 3.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 3.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 4.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 2.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 4.3 GO:0016209 antioxidant activity(GO:0016209)
0.1 1.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.8 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.1 28.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 0.8 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.6 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 2.5 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 1.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 3.8 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 261.9 GO:0046872 metal ion binding(GO:0046872)
0.1 1.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 1.3 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 1.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 2.0 GO:0008066 glutamate receptor activity(GO:0008066)
0.0 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.6 GO:0045503 dynein light chain binding(GO:0045503)
0.0 2.9 GO:0019843 rRNA binding(GO:0019843)
0.0 4.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.6 GO:0070513 death domain binding(GO:0070513)
0.0 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 1.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 2.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.9 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 1.8 GO:0001618 virus receptor activity(GO:0001618)
0.0 1.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 2.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.9 GO:0017048 Rho GTPase binding(GO:0017048)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 15.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.5 11.6 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.4 24.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.3 10.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.3 6.9 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.3 9.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.3 7.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 3.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 3.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.2 12.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2 16.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.2 0.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 3.0 PID RHOA PATHWAY RhoA signaling pathway
0.1 4.1 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 5.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 2.7 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 2.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 10.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 2.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 1.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 2.0 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 3.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 1.4 ST GA12 PATHWAY G alpha 12 Pathway
0.1 2.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 1.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 3.8 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 2.5 PID FGF PATHWAY FGF signaling pathway
0.0 1.0 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.6 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 3.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 4.2 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.9 24.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.5 12.4 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.5 26.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.4 10.8 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.4 11.6 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.4 6.9 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.3 10.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.3 10.8 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.3 8.8 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.3 29.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.3 9.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.3 5.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.3 10.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.3 113.0 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.2 7.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 4.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 5.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.2 3.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 8.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 2.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 3.1 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.2 4.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 2.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 7.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 9.3 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.2 1.6 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.2 2.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 4.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 4.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 9.5 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.1 4.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 2.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 5.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 3.0 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 1.5 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 3.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 4.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.6 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 1.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 2.0 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 0.8 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 1.0 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 2.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 3.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 2.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 2.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.4 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport