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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for PITX1

Z-value: 1.72

Motif logo

Transcription factors associated with PITX1

Gene Symbol Gene ID Gene Info
ENSG00000069011.11 paired like homeodomain 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PITX1hg19_v2_chr5_-_134369973_134369988-0.128.7e-02Click!

Activity profile of PITX1 motif

Sorted Z-values of PITX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_1077393 28.02 ENST00000590577.1
histocompatibility (minor) HA-1
chr7_+_73623717 22.67 ENST00000344995.5
ENST00000460943.1
linker for activation of T cells family, member 2
chr22_-_17680472 19.98 ENST00000330232.4
cat eye syndrome chromosome region, candidate 1
chr22_-_43036607 18.82 ENST00000505920.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr14_+_35747825 16.93 ENST00000540871.1
proteasome (prosome, macropain) subunit, alpha type, 6
chr12_-_54691668 16.92 ENST00000553198.1
nuclear factor, erythroid 2
chr7_+_73624327 16.00 ENST00000361082.3
ENST00000275635.7
ENST00000470709.1
linker for activation of T cells family, member 2
chr13_+_43597269 15.92 ENST00000379221.2
DnaJ (Hsp40) homolog, subfamily C, member 15
chr19_-_39826639 15.88 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
glia maturation factor, gamma
chr2_+_234104079 15.60 ENST00000417661.1
inositol polyphosphate-5-phosphatase, 145kDa
chr3_-_64009658 15.44 ENST00000394431.2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr12_+_53836339 15.36 ENST00000549135.1
proline rich 13
chr20_+_55926274 15.03 ENST00000371242.2
ENST00000527947.1
ribonucleic acid export 1
chr16_+_30087288 14.94 ENST00000279387.7
ENST00000562664.1
ENST00000562222.1
protein phosphatase 4, catalytic subunit
chr4_+_57843876 14.74 ENST00000450656.1
ENST00000381227.1
polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
chr2_-_62115725 13.82 ENST00000538252.1
ENST00000544079.1
ENST00000394440.3
chaperonin containing TCP1, subunit 4 (delta)
chr11_-_73693875 13.62 ENST00000536983.1
uncoupling protein 2 (mitochondrial, proton carrier)
chr11_-_118213455 13.50 ENST00000300692.4
CD3d molecule, delta (CD3-TCR complex)
chr20_+_35807449 12.94 ENST00000237530.6
ribophorin II
chr12_+_54892550 12.86 ENST00000545638.2
NCK-associated protein 1-like
chr3_-_49142504 12.72 ENST00000306125.6
ENST00000420147.2
glutaminyl-tRNA synthetase
chr3_-_141719195 12.67 ENST00000397991.4
transcription factor Dp-2 (E2F dimerization partner 2)
chr16_+_30212050 12.48 ENST00000563322.1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr11_-_118213360 12.43 ENST00000529594.1
CD3d molecule, delta (CD3-TCR complex)
chr17_-_61920280 12.31 ENST00000448276.2
ENST00000577990.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr7_-_5998714 12.18 ENST00000539903.1
radial spoke head 10 homolog B (Chlamydomonas)
chr8_-_101718991 12.13 ENST00000517990.1
poly(A) binding protein, cytoplasmic 1
chr20_+_35807512 11.99 ENST00000373622.5
ribophorin II
chr14_-_23285069 11.87 ENST00000554758.1
ENST00000397528.4
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr19_+_17865011 11.84 ENST00000596462.1
ENST00000596865.1
ENST00000598960.1
ENST00000539407.1
FCH domain only 1
chr20_+_57556263 11.75 ENST00000602795.1
ENST00000344018.3
negative elongation factor complex member C/D
chr6_+_31802364 11.68 ENST00000375640.3
ENST00000375641.2
chromosome 6 open reading frame 48
chr17_+_73230799 11.45 ENST00000579838.1
nucleoporin 85kDa
chr19_+_48824711 11.43 ENST00000599704.1
epithelial membrane protein 3
chr16_+_29472707 11.19 ENST00000565290.1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr19_+_41768401 11.19 ENST00000352456.3
ENST00000595018.1
ENST00000597725.1
heterogeneous nuclear ribonucleoprotein U-like 1
chr14_+_73563735 11.00 ENST00000532192.1
RNA binding motif protein 25
chr19_+_1071203 10.83 ENST00000543365.1
histocompatibility (minor) HA-1
chr19_+_24009879 10.65 ENST00000354585.4
ribosomal protein SA pseudogene 58
chr19_+_22469236 10.63 ENST00000357491.6
zinc finger protein 729
chr11_-_118213331 10.47 ENST00000392884.2
CD3d molecule, delta (CD3-TCR complex)
chr17_-_3599696 10.44 ENST00000225328.5
purinergic receptor P2X, ligand-gated ion channel, 5
chrX_-_70329118 10.34 ENST00000374188.3
interleukin 2 receptor, gamma
chr19_+_22469210 10.31 ENST00000601693.1
zinc finger protein 729
chr8_-_102218292 10.30 ENST00000518336.1
ENST00000520454.1
zinc finger protein 706
chr1_+_158815588 10.24 ENST00000438394.1
myeloid cell nuclear differentiation antigen
chr16_+_30483962 10.22 ENST00000356798.6
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr12_-_31945172 10.14 ENST00000340398.3
H3 histone, family 3C
chr19_+_54609230 10.11 ENST00000420296.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
chr12_+_123949053 10.05 ENST00000350887.5
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr16_+_30210552 10.03 ENST00000338971.5
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr16_+_29471210 10.03 ENST00000360423.7
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr2_-_112642267 10.02 ENST00000341068.3
anaphase promoting complex subunit 1
chr16_+_30484021 10.01 ENST00000358164.5
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr6_-_42016385 9.99 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
cyclin D3
chr5_-_180666570 9.97 ENST00000509535.1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr19_-_17932314 9.84 ENST00000598577.1
ENST00000317306.7
ENST00000379695.5
insulin-like 3 (Leydig cell)
chrX_+_9431324 9.80 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
transducin (beta)-like 1X-linked
chr9_+_134065506 9.78 ENST00000483497.2
nucleoporin 214kDa
chr1_+_203830703 9.71 ENST00000414487.2
small nuclear ribonucleoprotein polypeptide E
chr16_-_68034470 9.65 ENST00000412757.2
dipeptidase 2
chr20_+_1093891 9.40 ENST00000333082.3
ENST00000381898.4
ENST00000381899.4
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr19_-_50529193 9.39 ENST00000596445.1
ENST00000599538.1
vaccinia related kinase 3
chr2_-_26251481 9.13 ENST00000599234.1
Uncharacterized protein
chr7_-_99699538 9.10 ENST00000343023.6
ENST00000303887.5
minichromosome maintenance complex component 7
chr2_-_197664366 8.99 ENST00000409364.3
ENST00000263956.3
general transcription factor IIIC, polypeptide 3, 102kDa
chr12_+_123942188 8.91 ENST00000526639.2
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr12_-_8043736 8.88 ENST00000539924.1
solute carrier family 2 (facilitated glucose transporter), member 14
chr6_-_31763721 8.80 ENST00000375663.3
valyl-tRNA synthetase
chr3_+_127317066 8.80 ENST00000265056.7
minichromosome maintenance complex component 2
chr20_+_55926583 8.76 ENST00000395840.2
ribonucleic acid export 1
chr17_-_34524157 8.75 ENST00000378354.4
ENST00000394484.1
chemokine (C-C motif) ligand 3-like 3
chr17_-_56358287 8.60 ENST00000225275.3
ENST00000340482.3
myeloperoxidase
chr22_-_42336209 8.59 ENST00000472374.2
centromere protein M
chr8_-_145652336 8.54 ENST00000529182.1
ENST00000526054.1
vacuolar protein sorting 28 homolog (S. cerevisiae)
chr1_+_45212074 8.53 ENST00000372217.1
kinesin family member 2C
chr1_-_153348067 8.51 ENST00000368737.3
S100 calcium binding protein A12
chr13_+_37574678 8.47 ENST00000389704.3
exosome component 8
chr7_+_117864815 8.47 ENST00000433239.1
ankyrin repeat domain 7
chr13_+_50070077 8.42 ENST00000378319.3
ENST00000426879.1
PHD finger protein 11
chr1_-_27952741 8.40 ENST00000399173.1
feline Gardner-Rasheed sarcoma viral oncogene homolog
chr17_-_34625719 8.30 ENST00000422211.2
ENST00000542124.1
chemokine (C-C motif) ligand 3-like 1
chr3_-_50375657 8.05 ENST00000395126.3
Ras association (RalGDS/AF-6) domain family member 1
chr3_-_52029958 8.03 ENST00000294189.6
ribosomal protein L29
chr12_-_54689532 8.00 ENST00000540264.2
ENST00000312156.4
nuclear factor, erythroid 2
chr1_-_153518270 8.00 ENST00000354332.4
ENST00000368716.4
S100 calcium binding protein A4
chr6_-_31508304 7.99 ENST00000376177.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr16_-_18801643 7.97 ENST00000322989.4
ENST00000563390.1
ribosomal protein S15a
chr1_-_150738261 7.90 ENST00000448301.2
ENST00000368985.3
cathepsin S
chr1_-_36937075 7.81 ENST00000464465.2
colony stimulating factor 3 receptor (granulocyte)
chr16_-_2314222 7.79 ENST00000566397.1
RNA binding protein S1, serine-rich domain
chr5_-_176433582 7.77 ENST00000506128.1
ubiquitin interaction motif containing 1
chr12_+_56324756 7.76 ENST00000331886.5
ENST00000555090.1
diacylglycerol kinase, alpha 80kDa
chr19_-_8642289 7.75 ENST00000596675.1
ENST00000338257.8
myosin IF
chr12_-_51718436 7.66 ENST00000544402.1
bridging integrator 2
chr5_-_176433693 7.59 ENST00000507513.1
ENST00000511320.1
ubiquitin interaction motif containing 1
chr17_-_3599492 7.58 ENST00000435558.1
ENST00000345901.3
purinergic receptor P2X, ligand-gated ion channel, 5
chr16_-_9030515 7.56 ENST00000535863.1
ENST00000381886.4
ubiquitin specific peptidase 7 (herpes virus-associated)
chr1_+_161185032 7.54 ENST00000367992.3
ENST00000289902.1
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
chr3_-_48647470 7.49 ENST00000203407.5
ubiquinol-cytochrome c reductase core protein I
chr22_+_32870661 7.43 ENST00000266087.7
F-box protein 7
chr8_-_54935001 7.43 ENST00000396401.3
ENST00000521604.2
transcription elongation factor A (SII), 1
chr2_+_208423840 7.39 ENST00000539789.1
cAMP responsive element binding protein 1
chr16_+_30211181 7.36 ENST00000395138.2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr7_-_99063769 7.15 ENST00000394186.3
ENST00000359832.4
ENST00000449683.1
ENST00000488775.1
ENST00000523680.1
ENST00000292475.3
ENST00000430982.1
ENST00000555673.1
ENST00000413834.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2
pentatricopeptide repeat domain 1
ATP5J2-PTCD1 readthrough
chr19_+_17622415 7.14 ENST00000252603.2
ENST00000600923.1
6-phosphogluconolactonase
chr17_+_60536002 7.11 ENST00000582809.1
tousled-like kinase 2
chr2_+_86426478 7.04 ENST00000254644.8
ENST00000605125.1
ENST00000337109.4
ENST00000409180.1
mitochondrial ribosomal protein L35
chr9_+_131217459 7.02 ENST00000497812.2
ENST00000393533.2
outer dense fiber of sperm tails 2
chr16_-_25026641 7.00 ENST00000289968.6
ENST00000303665.5
ENST00000455311.2
ENST00000441763.2
Rho GTPase activating protein 17
chr2_+_39005336 6.89 ENST00000409566.1
gem (nuclear organelle) associated protein 6
chrX_+_49294472 6.84 ENST00000361446.5
G antigen 12B
chr6_-_32160622 6.79 ENST00000487761.1
ENST00000375040.3
G-protein signaling modulator 3
chr7_+_99070464 6.77 ENST00000331410.5
ENST00000483089.1
ENST00000448667.1
ENST00000493485.1
zinc finger protein 789
chr3_+_38029462 6.72 ENST00000283713.6
villin-like
chr22_-_24096562 6.64 ENST00000398465.3
pre-B lymphocyte 3
chr1_-_9148495 6.64 ENST00000464985.1
ENST00000487835.1
ENST00000486632.1
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr6_-_30640811 6.64 ENST00000376442.3
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr1_+_144146808 6.61 ENST00000369190.5
ENST00000412624.2
ENST00000369365.3
neuroblastoma breakpoint family, member 8
chr9_+_42671887 6.57 ENST00000456520.1
ENST00000377391.3
COBW domain containing 7
chr5_+_172386419 6.54 ENST00000265100.2
ENST00000519239.1
ribosomal protein L26-like 1
chr7_-_102184083 6.45 ENST00000379357.5
polymerase (RNA) II (DNA directed) polypeptide J3
chr19_+_6361440 6.44 ENST00000245816.4
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr17_+_8191815 6.42 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RAN guanine nucleotide release factor
chr19_+_48828582 6.39 ENST00000270221.6
ENST00000596315.1
epithelial membrane protein 3
chr19_+_23299777 6.36 ENST00000597761.2
zinc finger protein 730
chr1_+_28562617 6.36 ENST00000497986.1
ENST00000335514.5
ENST00000468425.2
ENST00000465645.1
ATPase inhibitory factor 1
chr11_+_64863587 6.34 ENST00000530773.1
ENST00000279281.3
ENST00000529180.1
vacuolar protein sorting 51 homolog (S. cerevisiae)
chr12_-_109027643 6.34 ENST00000388962.3
ENST00000550948.1
selectin P ligand
chr1_+_45212051 6.33 ENST00000372222.3
kinesin family member 2C
chr22_+_40742497 6.33 ENST00000216194.7
adenylosuccinate lyase
chr7_-_72722783 6.33 ENST00000428206.1
ENST00000252594.6
ENST00000310326.8
ENST00000438747.2
NOP2/Sun domain family, member 5
chr6_+_16129308 6.27 ENST00000356840.3
ENST00000349606.4
myosin regulatory light chain interacting protein
chr14_-_23285011 6.22 ENST00000397532.3
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr16_+_29690358 6.22 ENST00000395384.4
ENST00000562473.1
quinolinate phosphoribosyltransferase
chr20_+_361261 6.18 ENST00000217233.3
tribbles pseudokinase 3
chr7_-_102283238 6.18 ENST00000340457.8
uroplakin 3B-like
chr11_+_10772534 6.18 ENST00000361367.2
CTR9, Paf1/RNA polymerase II complex component
chr16_+_29467127 6.15 ENST00000344620.6
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr1_-_154580616 6.11 ENST00000368474.4
adenosine deaminase, RNA-specific
chr16_-_28634874 6.11 ENST00000395609.1
ENST00000350842.4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr11_+_65647280 6.09 ENST00000307886.3
ENST00000528419.1
ENST00000526034.1
cathepsin W
chr12_-_8025623 6.07 ENST00000542782.1
ENST00000396589.2
ENST00000535266.1
ENST00000542505.1
solute carrier family 2 (facilitated glucose transporter), member 14
chr2_-_62115659 6.02 ENST00000544185.1
chaperonin containing TCP1, subunit 4 (delta)
chr17_-_8113886 6.01 ENST00000577833.1
ENST00000534871.1
ENST00000583915.1
ENST00000316199.6
ENST00000581511.1
ENST00000585124.1
aurora kinase B
chr16_-_68033356 6.01 ENST00000393847.1
ENST00000573808.1
ENST00000572624.1
dipeptidase 2
chr16_+_88869621 5.98 ENST00000301019.4
chromatin licensing and DNA replication factor 1
chr19_+_5690207 5.97 ENST00000347512.3
ribosomal protein L36
chr2_+_219110149 5.95 ENST00000456575.1
actin related protein 2/3 complex, subunit 2, 34kDa
chr6_+_139456226 5.93 ENST00000367658.2
headcase homolog (Drosophila)
chr12_-_14721283 5.93 ENST00000240617.5
phospholipase B domain containing 1
chr10_+_71029740 5.84 ENST00000450646.1
ENST00000360289.2
ENST00000448642.2
hexokinase 1
chr19_-_45953983 5.83 ENST00000592083.1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr12_-_118797475 5.77 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAO kinase 3
chr3_-_47517302 5.74 ENST00000441517.2
ENST00000545718.1
SREBF chaperone
chr12_-_53601055 5.70 ENST00000552972.1
ENST00000422257.3
ENST00000267082.5
integrin, beta 7
chr16_-_29499154 5.69 ENST00000354563.5
Uncharacterized protein
chr12_-_6677422 5.69 ENST00000382421.3
ENST00000545200.1
ENST00000399466.2
ENST00000536124.1
ENST00000540228.1
ENST00000542867.1
ENST00000545492.1
ENST00000322166.5
ENST00000545915.1
NOP2 nucleolar protein
chr4_+_2627159 5.68 ENST00000382839.3
ENST00000324666.5
ENST00000545951.1
ENST00000502458.1
ENST00000505311.1
family with sequence similarity 193, member A
chr19_+_22235310 5.66 ENST00000600162.1
zinc finger protein 257
chr6_-_31510181 5.63 ENST00000458640.1
ENST00000396172.1
ENST00000417556.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr20_+_3869423 5.63 ENST00000497424.1
pantothenate kinase 2
chr1_-_40042416 5.62 ENST00000372857.3
ENST00000372856.3
ENST00000531243.2
ENST00000451091.2
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr22_+_40742512 5.61 ENST00000454266.2
ENST00000342312.6
adenylosuccinate lyase
chr12_+_54891495 5.57 ENST00000293373.6
NCK-associated protein 1-like
chr7_-_102232891 5.54 ENST00000514917.2
RP11-514P8.7
chr1_+_144811744 5.52 ENST00000338347.4
ENST00000440491.2
ENST00000375552.4
neuroblastoma breakpoint family, member 9
chr2_-_74692473 5.51 ENST00000535045.1
ENST00000409065.1
ENST00000414701.1
ENST00000448666.1
ENST00000233616.4
ENST00000452063.2
mannosyl-oligosaccharide glucosidase
chr2_+_39005325 5.51 ENST00000281950.3
gem (nuclear organelle) associated protein 6
chr19_-_10305752 5.50 ENST00000540357.1
ENST00000359526.4
ENST00000340748.4
DNA (cytosine-5-)-methyltransferase 1
chr16_+_85832146 5.50 ENST00000565078.1
cytochrome c oxidase subunit IV isoform 1
chr1_-_11115877 5.50 ENST00000490101.1
spermidine synthase
chr13_+_25670268 5.49 ENST00000281589.3
poly(A) binding protein, cytoplasmic 3
chrX_-_71497148 5.49 ENST00000316084.6
ribosomal protein S4, X-linked
chr17_+_41158742 5.48 ENST00000415816.2
ENST00000438323.2
interferon-induced protein 35
chr6_-_41909561 5.46 ENST00000372991.4
cyclin D3
chr11_-_67211263 5.46 ENST00000393893.1
coronin, actin binding protein, 1B
chr12_+_7055631 5.44 ENST00000543115.1
ENST00000399448.1
protein tyrosine phosphatase, non-receptor type 6
chr3_+_112051347 5.41 ENST00000606471.1
CD200 molecule
chr19_+_52932435 5.38 ENST00000301085.4
zinc finger protein 534
chr6_+_32938665 5.38 ENST00000374831.4
ENST00000395289.2
bromodomain containing 2
chr7_+_66386204 5.37 ENST00000341567.4
ENST00000607045.1
transmembrane protein 248
chr5_+_118691706 5.36 ENST00000415806.2
tumor necrosis factor, alpha-induced protein 8
chr19_+_54704610 5.33 ENST00000302907.4
ribosomal protein S9
chr7_-_76247617 5.30 ENST00000441393.1
POM121 and ZP3 fusion
chr15_+_78832747 5.29 ENST00000560217.1
ENST00000044462.7
ENST00000559082.1
ENST00000559948.1
ENST00000413382.2
ENST00000559146.1
ENST00000558281.1
proteasome (prosome, macropain) subunit, alpha type, 4
chr19_+_50321528 5.28 ENST00000312865.6
ENST00000595185.1
ENST00000538643.1
mediator complex subunit 25
chr19_-_36399149 5.28 ENST00000585901.2
ENST00000544690.2
ENST00000424586.3
ENST00000262629.4
ENST00000589517.1
TYRO protein tyrosine kinase binding protein
chr3_+_52448539 5.26 ENST00000461861.1
PHD finger protein 7
chr10_-_30638090 5.24 ENST00000421701.1
ENST00000263063.4
mitochondrial poly(A) polymerase
chr19_+_36027660 5.24 ENST00000585510.1
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr14_+_21249200 5.24 ENST00000304677.2
ribonuclease, RNase A family, k6
chr5_+_32531893 5.23 ENST00000512913.1
SUB1 homolog (S. cerevisiae)
chr4_-_24586140 5.19 ENST00000336812.4
DEAH (Asp-Glu-Ala-His) box helicase 15
chr19_+_17862274 5.19 ENST00000596536.1
ENST00000593870.1
ENST00000598086.1
ENST00000598932.1
ENST00000595023.1
ENST00000594068.1
ENST00000596507.1
ENST00000595033.1
ENST00000597718.1
FCH domain only 1
chr5_-_140013275 5.18 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14 molecule
chr3_+_186739636 5.18 ENST00000440338.1
ENST00000448044.1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr19_-_14889349 5.18 ENST00000315576.3
ENST00000392967.2
ENST00000346057.1
ENST00000353876.1
ENST00000353005.1
egf-like module containing, mucin-like, hormone receptor-like 2
chr13_+_98612446 5.16 ENST00000496368.1
ENST00000421861.2
ENST00000357602.3
importin 5
chr1_-_148347506 5.15 ENST00000369189.3
neuroblastoma breakpoint family, member 20

Network of associatons between targets according to the STRING database.

First level regulatory network of PITX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 15.6 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
4.9 34.3 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
4.9 9.8 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
4.6 18.4 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) actin polymerization-dependent cell motility(GO:0070358)
4.3 13.0 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
4.1 12.3 GO:2000397 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
4.0 11.9 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
3.7 11.2 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
3.3 13.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
3.0 21.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
3.0 18.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
2.8 17.0 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
2.8 11.3 GO:0036034 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
2.8 16.9 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
2.8 36.4 GO:0045059 positive thymic T cell selection(GO:0045059)
2.6 12.9 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
2.5 7.5 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812) positive regulation of mast cell cytokine production(GO:0032765) mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
2.4 9.5 GO:0033277 abortive mitotic cell cycle(GO:0033277)
2.4 7.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
2.3 14.0 GO:0045903 positive regulation of translational fidelity(GO:0045903)
2.3 22.5 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
2.1 8.5 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
2.1 6.3 GO:0050902 leukocyte adhesive activation(GO:0050902)
2.1 10.3 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
2.0 6.1 GO:1900368 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
2.0 6.0 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
2.0 23.8 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
1.9 11.6 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
1.9 13.3 GO:0015755 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
1.8 16.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
1.7 1.7 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
1.7 17.1 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
1.7 17.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.7 10.2 GO:0035803 egg coat formation(GO:0035803)
1.7 8.4 GO:0007619 courtship behavior(GO:0007619)
1.7 10.0 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
1.6 4.9 GO:0033364 mast cell secretory granule organization(GO:0033364)
1.6 6.4 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
1.6 12.5 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
1.5 4.6 GO:0035915 pore formation in membrane of other organism(GO:0035915)
1.5 13.6 GO:1901977 negative regulation of cell cycle checkpoint(GO:1901977) negative regulation of DNA damage checkpoint(GO:2000002)
1.5 1.5 GO:2001020 regulation of response to DNA damage stimulus(GO:2001020)
1.5 37.2 GO:0006337 nucleosome disassembly(GO:0006337)
1.5 4.4 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
1.4 10.1 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
1.4 5.7 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
1.4 14.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
1.4 2.8 GO:1902661 negative regulation of histone H3-K9 dimethylation(GO:1900110) positive regulation of glucose mediated signaling pathway(GO:1902661)
1.4 41.8 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
1.4 4.1 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
1.4 10.9 GO:0070475 rRNA base methylation(GO:0070475)
1.4 18.9 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
1.3 4.0 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
1.3 8.0 GO:0042780 tRNA 3'-end processing(GO:0042780)
1.3 2.6 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
1.3 6.5 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
1.3 5.2 GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
1.3 8.9 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
1.2 5.0 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
1.2 6.2 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
1.2 5.0 GO:0021796 cerebral cortex regionalization(GO:0021796)
1.2 2.5 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
1.2 7.4 GO:0032621 interleukin-18 production(GO:0032621)
1.2 6.0 GO:0045914 negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
1.2 3.6 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
1.2 4.7 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
1.2 8.1 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
1.1 3.4 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
1.1 7.8 GO:0008295 spermidine biosynthetic process(GO:0008295)
1.1 6.6 GO:0006741 NADP biosynthetic process(GO:0006741)
1.1 13.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
1.1 3.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
1.1 2.1 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
1.1 51.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
1.0 10.3 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
1.0 3.1 GO:0006447 regulation of translational initiation by iron(GO:0006447)
1.0 21.4 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
1.0 4.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
1.0 8.6 GO:0001878 response to yeast(GO:0001878)
1.0 2.9 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
1.0 2.9 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.9 9.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.9 17.8 GO:0032060 bleb assembly(GO:0032060)
0.9 7.4 GO:1903599 positive regulation of mitophagy(GO:1903599)
0.9 2.7 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.9 2.7 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.9 28.0 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.9 6.3 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.9 4.5 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.9 10.5 GO:0006089 lactate metabolic process(GO:0006089)
0.9 2.6 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.8 2.5 GO:2000670 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.8 4.2 GO:2000110 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) negative regulation of macrophage apoptotic process(GO:2000110)
0.8 3.3 GO:0043248 proteasome assembly(GO:0043248)
0.8 5.8 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.8 2.5 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.8 5.7 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.8 4.0 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.8 2.4 GO:0002352 B cell selection(GO:0002339) B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.8 44.0 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.8 7.2 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.8 0.8 GO:0002316 follicular B cell differentiation(GO:0002316)
0.8 14.2 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.8 4.7 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.8 2.3 GO:0051037 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.8 3.1 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.8 6.9 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.8 3.0 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.8 2.3 GO:0072229 isoleucine catabolic process(GO:0006550) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.8 2.3 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.7 3.7 GO:0033384 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.7 2.2 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.7 3.0 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.7 2.2 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.7 5.9 GO:0032790 ribosome disassembly(GO:0032790)
0.7 22.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.7 2.2 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
0.7 0.7 GO:0090662 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.7 2.9 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.7 2.2 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.7 9.4 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.7 2.2 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.7 27.0 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.7 5.6 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.7 4.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.7 2.1 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.7 1.3 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.7 4.6 GO:0006772 thiamine metabolic process(GO:0006772)
0.7 7.3 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.7 2.6 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.7 3.9 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.7 42.7 GO:0002279 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.6 3.8 GO:0006642 triglyceride mobilization(GO:0006642)
0.6 3.8 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.6 10.0 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.6 5.6 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.6 5.0 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.6 5.0 GO:0006116 NADH oxidation(GO:0006116)
0.6 6.7 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.6 1.8 GO:0072719 cellular response to cisplatin(GO:0072719)
0.6 53.2 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.6 2.4 GO:0070982 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.6 10.7 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.6 1.8 GO:0009183 purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183) dGDP metabolic process(GO:0046066)
0.6 10.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.6 3.5 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.6 2.3 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.6 7.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.6 2.9 GO:0003051 brain renin-angiotensin system(GO:0002035) angiotensin-mediated drinking behavior(GO:0003051)
0.6 33.4 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.6 1.7 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.6 5.0 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.5 15.8 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.5 4.3 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.5 1.6 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.5 1.6 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.5 21.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.5 77.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.5 5.9 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.5 5.3 GO:0001973 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.5 4.7 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.5 2.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.5 2.6 GO:0098502 DNA dephosphorylation(GO:0098502)
0.5 9.2 GO:0072540 T-helper cell lineage commitment(GO:0002295) T-helper 17 cell lineage commitment(GO:0072540)
0.5 4.5 GO:0051014 actin filament severing(GO:0051014)
0.5 2.5 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.5 2.5 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.5 1.5 GO:0034127 regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034127)
0.5 1.4 GO:0046368 GDP-L-fucose biosynthetic process(GO:0042350) 'de novo' GDP-L-fucose biosynthetic process(GO:0042351) GDP-L-fucose metabolic process(GO:0046368)
0.5 1.9 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.5 1.9 GO:0016139 glycoside catabolic process(GO:0016139) glycosylceramide catabolic process(GO:0046477)
0.5 15.9 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.5 21.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.5 4.6 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.5 2.3 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.5 6.5 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.5 11.0 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.5 1.4 GO:0006059 hexitol metabolic process(GO:0006059)
0.5 1.8 GO:0042631 cellular response to water deprivation(GO:0042631)
0.4 1.3 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.4 2.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.4 10.2 GO:0051194 positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.4 3.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.4 4.0 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.4 2.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.4 4.3 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.4 3.9 GO:0060754 regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754)
0.4 3.0 GO:0007519 skeletal muscle tissue development(GO:0007519) skeletal muscle organ development(GO:0060538)
0.4 3.9 GO:0046689 response to mercury ion(GO:0046689)
0.4 3.0 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.4 4.6 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.4 2.1 GO:0048539 bone marrow development(GO:0048539)
0.4 1.3 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.4 3.6 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.4 0.8 GO:0006788 heme oxidation(GO:0006788)
0.4 8.8 GO:0097186 amelogenesis(GO:0097186)
0.4 7.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.4 1.2 GO:0044805 late nucleophagy(GO:0044805)
0.4 2.3 GO:0015693 magnesium ion transport(GO:0015693)
0.4 2.3 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.4 2.3 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.4 10.6 GO:0000042 protein targeting to Golgi(GO:0000042)
0.4 4.5 GO:0016236 macroautophagy(GO:0016236)
0.4 1.1 GO:1990910 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) response to hypobaric hypoxia(GO:1990910)
0.4 7.8 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.4 5.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.4 4.8 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.4 7.7 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.4 8.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.3 2.4 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.3 24.7 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.3 1.7 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.3 4.1 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.3 1.4 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.3 6.1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.3 1.3 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.3 3.3 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.3 3.9 GO:0032042 mitochondrial DNA metabolic process(GO:0032042)
0.3 1.3 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.3 1.9 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.3 7.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.3 3.1 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
0.3 3.0 GO:0042262 DNA protection(GO:0042262)
0.3 4.2 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.3 0.3 GO:0051031 tRNA transport(GO:0051031)
0.3 3.6 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.3 5.6 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.3 2.4 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.3 2.4 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.3 3.2 GO:0051601 exocyst localization(GO:0051601)
0.3 12.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.3 2.8 GO:0042373 vitamin K metabolic process(GO:0042373)
0.3 3.0 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.3 3.7 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.3 1.0 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.3 5.4 GO:0097320 membrane tubulation(GO:0097320)
0.3 0.8 GO:0043605 cellular amide catabolic process(GO:0043605)
0.3 3.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.3 1.3 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.2 2.2 GO:0009249 protein lipoylation(GO:0009249)
0.2 2.5 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.2 10.1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.2 4.6 GO:0002643 regulation of tolerance induction(GO:0002643)
0.2 0.5 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.2 0.9 GO:1904796 regulation of core promoter binding(GO:1904796)
0.2 17.5 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 1.6 GO:1902969 mitotic DNA replication(GO:1902969)
0.2 0.7 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.2 2.8 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.2 2.7 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086) positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.2 2.5 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 3.9 GO:0035641 locomotory exploration behavior(GO:0035641)
0.2 4.3 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.2 0.5 GO:0015743 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.2 3.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.2 2.0 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.2 1.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.2 1.9 GO:0051085 'de novo' posttranslational protein folding(GO:0051084) chaperone mediated protein folding requiring cofactor(GO:0051085)
0.2 0.9 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.2 0.9 GO:0070245 snRNA transcription from RNA polymerase III promoter(GO:0042796) positive regulation of thymocyte apoptotic process(GO:0070245)
0.2 1.7 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.2 10.3 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.2 2.9 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.2 3.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 0.2 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.2 0.8 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.2 57.0 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.2 1.4 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.2 4.3 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.2 3.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 0.4 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.2 0.4 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.2 19.3 GO:0034728 nucleosome organization(GO:0034728)
0.2 0.9 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.2 1.6 GO:0072520 seminiferous tubule development(GO:0072520)
0.2 2.8 GO:0007220 Notch receptor processing(GO:0007220)
0.2 5.4 GO:0043068 positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.2 1.2 GO:0016180 snRNA processing(GO:0016180)
0.2 0.9 GO:1903911 positive regulation of receptor clustering(GO:1903911)
0.2 3.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 4.7 GO:0001881 receptor recycling(GO:0001881)
0.2 1.9 GO:0048003 antigen processing and presentation via MHC class Ib(GO:0002475) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.2 2.6 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.2 1.4 GO:1904646 cellular response to beta-amyloid(GO:1904646)
0.2 1.9 GO:0044065 regulation of respiratory system process(GO:0044065)
0.2 0.5 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.1 0.9 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.6 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 5.3 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.1 2.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 3.9 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 3.7 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 3.7 GO:0034383 low-density lipoprotein particle clearance(GO:0034383)
0.1 1.4 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.1 1.1 GO:0045047 protein targeting to ER(GO:0045047)
0.1 0.5 GO:0000023 maltose metabolic process(GO:0000023)
0.1 1.4 GO:0042940 D-amino acid transport(GO:0042940)
0.1 1.2 GO:0030916 otic vesicle formation(GO:0030916)
0.1 1.1 GO:0015816 glycine transport(GO:0015816)
0.1 1.0 GO:0010624 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.1 1.3 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1 2.3 GO:0032418 lysosome localization(GO:0032418)
0.1 4.1 GO:0032527 protein exit from endoplasmic reticulum(GO:0032527)
0.1 0.6 GO:0007635 chemosensory behavior(GO:0007635)
0.1 1.5 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 3.8 GO:0032508 DNA duplex unwinding(GO:0032508)
0.1 3.7 GO:0030261 chromosome condensation(GO:0030261)
0.1 9.8 GO:0016575 histone deacetylation(GO:0016575)
0.1 1.3 GO:0016050 vesicle organization(GO:0016050)
0.1 3.6 GO:0050832 defense response to fungus(GO:0050832)
0.1 0.6 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.5 GO:0048840 otolith development(GO:0048840)
0.1 8.4 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.1 1.9 GO:0097421 liver regeneration(GO:0097421)
0.1 0.1 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.1 1.5 GO:0014029 neural crest formation(GO:0014029)
0.1 1.2 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 0.9 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 3.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.6 GO:0035799 ureter maturation(GO:0035799)
0.1 3.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.1 0.7 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 14.0 GO:0006401 RNA catabolic process(GO:0006401)
0.1 1.4 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 2.0 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.1 1.8 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.1 0.6 GO:0031648 protein destabilization(GO:0031648)
0.1 0.4 GO:1905247 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.1 0.2 GO:0042255 ribosome assembly(GO:0042255)
0.1 5.4 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.1 1.2 GO:0001701 in utero embryonic development(GO:0001701)
0.1 2.1 GO:0007140 male meiosis(GO:0007140)
0.1 1.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.4 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.1 0.5 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 2.1 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.1 3.1 GO:0030890 positive regulation of B cell proliferation(GO:0030890)
0.1 1.6 GO:0005513 detection of calcium ion(GO:0005513)
0.1 1.0 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) protein O-linked fucosylation(GO:0036066)
0.1 0.6 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.6 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 2.0 GO:0006833 water transport(GO:0006833)
0.1 0.3 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 1.5 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.1 2.1 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.1 4.7 GO:0050871 positive regulation of B cell activation(GO:0050871)
0.1 2.4 GO:0001504 neurotransmitter uptake(GO:0001504)
0.1 8.1 GO:0002377 immunoglobulin production(GO:0002377)
0.1 1.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 2.7 GO:0000060 protein import into nucleus, translocation(GO:0000060)
0.1 0.8 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 2.6 GO:0032456 endocytic recycling(GO:0032456)
0.1 0.3 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.8 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.1 1.2 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.3 GO:0090527 actin filament reorganization(GO:0090527)
0.1 1.9 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.7 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.1 1.0 GO:0006020 inositol metabolic process(GO:0006020)
0.1 1.8 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 1.8 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 3.9 GO:0030183 B cell differentiation(GO:0030183)
0.1 4.7 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 1.6 GO:0048753 melanosome organization(GO:0032438) pigment granule organization(GO:0048753)
0.1 1.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 2.1 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 1.6 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.1 5.1 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.1 2.5 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.1 1.2 GO:0000462</