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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for PITX1

Z-value: 1.72

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Transcription factors associated with PITX1

Gene Symbol Gene ID Gene Info
PITX1
ENSG00000069011.11 paired like homeodomain 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PITX1hg19_v2_chr5_-_134369973_134369988-0.128.7e-02Click!

Activity profile of PITX1 motif

Sorted Z-values of PITX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_1077393 28.02 ENST00000590577.1
HMHA1
histocompatibility (minor) HA-1
chr7_+_73623717 22.67 ENST00000344995.5
ENST00000460943.1
LAT2
linker for activation of T cells family, member 2
chr22_-_17680472 19.98 ENST00000330232.4
CECR1
cat eye syndrome chromosome region, candidate 1
chr22_-_43036607 18.82 ENST00000505920.1
ATP5L2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr14_+_35747825 16.93 ENST00000540871.1
PSMA6
proteasome (prosome, macropain) subunit, alpha type, 6
chr12_-_54691668 16.92 ENST00000553198.1
NFE2
nuclear factor, erythroid 2
chr7_+_73624327 16.00 ENST00000361082.3
ENST00000275635.7
ENST00000470709.1
LAT2
linker for activation of T cells family, member 2
chr13_+_43597269 15.92 ENST00000379221.2
DNAJC15
DnaJ (Hsp40) homolog, subfamily C, member 15
chr19_-_39826639 15.88 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
GMFG
glia maturation factor, gamma
chr2_+_234104079 15.60 ENST00000417661.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr3_-_64009658 15.44 ENST00000394431.2
PSMD6
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr12_+_53836339 15.36 ENST00000549135.1
PRR13
proline rich 13
chr20_+_55926274 15.03 ENST00000371242.2
ENST00000527947.1
RAE1
ribonucleic acid export 1
chr16_+_30087288 14.94 ENST00000279387.7
ENST00000562664.1
ENST00000562222.1
PPP4C
protein phosphatase 4, catalytic subunit
chr4_+_57843876 14.74 ENST00000450656.1
ENST00000381227.1
POLR2B
polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
chr2_-_62115725 13.82 ENST00000538252.1
ENST00000544079.1
ENST00000394440.3
CCT4
chaperonin containing TCP1, subunit 4 (delta)
chr11_-_73693875 13.62 ENST00000536983.1
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr11_-_118213455 13.50 ENST00000300692.4
CD3D
CD3d molecule, delta (CD3-TCR complex)
chr20_+_35807449 12.94 ENST00000237530.6
RPN2
ribophorin II
chr12_+_54892550 12.86 ENST00000545638.2
NCKAP1L
NCK-associated protein 1-like
chr3_-_49142504 12.72 ENST00000306125.6
ENST00000420147.2
QARS
glutaminyl-tRNA synthetase
chr3_-_141719195 12.67 ENST00000397991.4
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr16_+_30212050 12.48 ENST00000563322.1
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr11_-_118213360 12.43 ENST00000529594.1
CD3D
CD3d molecule, delta (CD3-TCR complex)
chr17_-_61920280 12.31 ENST00000448276.2
ENST00000577990.1
SMARCD2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr7_-_5998714 12.18 ENST00000539903.1
RSPH10B
radial spoke head 10 homolog B (Chlamydomonas)
chr8_-_101718991 12.13 ENST00000517990.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr20_+_35807512 11.99 ENST00000373622.5
RPN2
ribophorin II
chr14_-_23285069 11.87 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr19_+_17865011 11.84 ENST00000596462.1
ENST00000596865.1
ENST00000598960.1
ENST00000539407.1
FCHO1
FCH domain only 1
chr20_+_57556263 11.75 ENST00000602795.1
ENST00000344018.3
NELFCD
negative elongation factor complex member C/D
chr6_+_31802364 11.68 ENST00000375640.3
ENST00000375641.2
C6orf48
chromosome 6 open reading frame 48
chr17_+_73230799 11.45 ENST00000579838.1
NUP85
nucleoporin 85kDa
chr19_+_48824711 11.43 ENST00000599704.1
EMP3
epithelial membrane protein 3
chr16_+_29472707 11.19 ENST00000565290.1
SULT1A4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr19_+_41768401 11.19 ENST00000352456.3
ENST00000595018.1
ENST00000597725.1
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr14_+_73563735 11.00 ENST00000532192.1
RBM25
RNA binding motif protein 25
chr19_+_1071203 10.83 ENST00000543365.1
HMHA1
histocompatibility (minor) HA-1
chr19_+_24009879 10.65 ENST00000354585.4
RPSAP58
ribosomal protein SA pseudogene 58
chr19_+_22469236 10.63 ENST00000357491.6
ZNF729
zinc finger protein 729
chr11_-_118213331 10.47 ENST00000392884.2
CD3D
CD3d molecule, delta (CD3-TCR complex)
chr17_-_3599696 10.44 ENST00000225328.5
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chrX_-_70329118 10.34 ENST00000374188.3
IL2RG
interleukin 2 receptor, gamma
chr19_+_22469210 10.31 ENST00000601693.1
ZNF729
zinc finger protein 729
chr8_-_102218292 10.30 ENST00000518336.1
ENST00000520454.1
ZNF706
zinc finger protein 706
chr1_+_158815588 10.24 ENST00000438394.1
MNDA
myeloid cell nuclear differentiation antigen
chr16_+_30483962 10.22 ENST00000356798.6
ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr12_-_31945172 10.14 ENST00000340398.3
H3F3C
H3 histone, family 3C
chr19_+_54609230 10.11 ENST00000420296.1
NDUFA3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
chr12_+_123949053 10.05 ENST00000350887.5
SNRNP35
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr16_+_30210552 10.03 ENST00000338971.5
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr16_+_29471210 10.03 ENST00000360423.7
SULT1A4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr2_-_112642267 10.02 ENST00000341068.3
ANAPC1
anaphase promoting complex subunit 1
chr16_+_30484021 10.01 ENST00000358164.5
ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr6_-_42016385 9.99 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
CCND3
cyclin D3
chr5_-_180666570 9.97 ENST00000509535.1
GNB2L1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr19_-_17932314 9.84 ENST00000598577.1
ENST00000317306.7
ENST00000379695.5
INSL3
insulin-like 3 (Leydig cell)
chrX_+_9431324 9.80 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr9_+_134065506 9.78 ENST00000483497.2
NUP214
nucleoporin 214kDa
chr1_+_203830703 9.71 ENST00000414487.2
SNRPE
small nuclear ribonucleoprotein polypeptide E
chr16_-_68034470 9.65 ENST00000412757.2
DPEP2
dipeptidase 2
chr20_+_1093891 9.40 ENST00000333082.3
ENST00000381898.4
ENST00000381899.4
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr19_-_50529193 9.39 ENST00000596445.1
ENST00000599538.1
VRK3
vaccinia related kinase 3
chr2_-_26251481 9.13 ENST00000599234.1
AC013449.1
Uncharacterized protein
chr7_-_99699538 9.10 ENST00000343023.6
ENST00000303887.5
MCM7
minichromosome maintenance complex component 7
chr2_-_197664366 8.99 ENST00000409364.3
ENST00000263956.3
GTF3C3
general transcription factor IIIC, polypeptide 3, 102kDa
chr12_+_123942188 8.91 ENST00000526639.2
SNRNP35
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr12_-_8043736 8.88 ENST00000539924.1
SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14
chr6_-_31763721 8.80 ENST00000375663.3
VARS
valyl-tRNA synthetase
chr3_+_127317066 8.80 ENST00000265056.7
MCM2
minichromosome maintenance complex component 2
chr20_+_55926583 8.76 ENST00000395840.2
RAE1
ribonucleic acid export 1
chr17_-_34524157 8.75 ENST00000378354.4
ENST00000394484.1
CCL3L3
chemokine (C-C motif) ligand 3-like 3
chr17_-_56358287 8.60 ENST00000225275.3
ENST00000340482.3
MPO
myeloperoxidase
chr22_-_42336209 8.59 ENST00000472374.2
CENPM
centromere protein M
chr8_-_145652336 8.54 ENST00000529182.1
ENST00000526054.1
VPS28
vacuolar protein sorting 28 homolog (S. cerevisiae)
chr1_+_45212074 8.53 ENST00000372217.1
KIF2C
kinesin family member 2C
chr1_-_153348067 8.51 ENST00000368737.3
S100A12
S100 calcium binding protein A12
chr13_+_37574678 8.47 ENST00000389704.3
EXOSC8
exosome component 8
chr7_+_117864815 8.47 ENST00000433239.1
ANKRD7
ankyrin repeat domain 7
chr13_+_50070077 8.42 ENST00000378319.3
ENST00000426879.1
PHF11
PHD finger protein 11
chr1_-_27952741 8.40 ENST00000399173.1
FGR
feline Gardner-Rasheed sarcoma viral oncogene homolog
chr17_-_34625719 8.30 ENST00000422211.2
ENST00000542124.1
CCL3L1
chemokine (C-C motif) ligand 3-like 1
chr3_-_50375657 8.05 ENST00000395126.3
RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr3_-_52029958 8.03 ENST00000294189.6
RPL29
ribosomal protein L29
chr12_-_54689532 8.00 ENST00000540264.2
ENST00000312156.4
NFE2
nuclear factor, erythroid 2
chr1_-_153518270 8.00 ENST00000354332.4
ENST00000368716.4
S100A4
S100 calcium binding protein A4
chr6_-_31508304 7.99 ENST00000376177.2
DDX39B
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr16_-_18801643 7.97 ENST00000322989.4
ENST00000563390.1
RPS15A
ribosomal protein S15a
chr1_-_150738261 7.90 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr1_-_36937075 7.81 ENST00000464465.2
CSF3R
colony stimulating factor 3 receptor (granulocyte)
chr16_-_2314222 7.79 ENST00000566397.1
RNPS1
RNA binding protein S1, serine-rich domain
chr5_-_176433582 7.77 ENST00000506128.1
UIMC1
ubiquitin interaction motif containing 1
chr12_+_56324756 7.76 ENST00000331886.5
ENST00000555090.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr19_-_8642289 7.75 ENST00000596675.1
ENST00000338257.8
MYO1F
myosin IF
chr12_-_51718436 7.66 ENST00000544402.1
BIN2
bridging integrator 2
chr5_-_176433693 7.59 ENST00000507513.1
ENST00000511320.1
UIMC1
ubiquitin interaction motif containing 1
chr17_-_3599492 7.58 ENST00000435558.1
ENST00000345901.3
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr16_-_9030515 7.56 ENST00000535863.1
ENST00000381886.4
USP7
ubiquitin specific peptidase 7 (herpes virus-associated)
chr1_+_161185032 7.54 ENST00000367992.3
ENST00000289902.1
FCER1G
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
chr3_-_48647470 7.49 ENST00000203407.5
UQCRC1
ubiquinol-cytochrome c reductase core protein I
chr22_+_32870661 7.43 ENST00000266087.7
FBXO7
F-box protein 7
chr8_-_54935001 7.43 ENST00000396401.3
ENST00000521604.2
TCEA1
transcription elongation factor A (SII), 1
chr2_+_208423840 7.39 ENST00000539789.1
CREB1
cAMP responsive element binding protein 1
chr16_+_30211181 7.36 ENST00000395138.2
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr7_-_99063769 7.15 ENST00000394186.3
ENST00000359832.4
ENST00000449683.1
ENST00000488775.1
ENST00000523680.1
ENST00000292475.3
ENST00000430982.1
ENST00000555673.1
ENST00000413834.1
ATP5J2
PTCD1
ATP5J2-PTCD1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2
pentatricopeptide repeat domain 1
ATP5J2-PTCD1 readthrough
chr19_+_17622415 7.14 ENST00000252603.2
ENST00000600923.1
PGLS
6-phosphogluconolactonase
chr17_+_60536002 7.11 ENST00000582809.1
TLK2
tousled-like kinase 2
chr2_+_86426478 7.04 ENST00000254644.8
ENST00000605125.1
ENST00000337109.4
ENST00000409180.1
MRPL35
mitochondrial ribosomal protein L35
chr9_+_131217459 7.02 ENST00000497812.2
ENST00000393533.2
ODF2
outer dense fiber of sperm tails 2
chr16_-_25026641 7.00 ENST00000289968.6
ENST00000303665.5
ENST00000455311.2
ENST00000441763.2
ARHGAP17
Rho GTPase activating protein 17
chr2_+_39005336 6.89 ENST00000409566.1
GEMIN6
gem (nuclear organelle) associated protein 6
chrX_+_49294472 6.84 ENST00000361446.5
GAGE12B
G antigen 12B
chr6_-_32160622 6.79 ENST00000487761.1
ENST00000375040.3
GPSM3
G-protein signaling modulator 3
chr7_+_99070464 6.77 ENST00000331410.5
ENST00000483089.1
ENST00000448667.1
ENST00000493485.1
ZNF789
zinc finger protein 789
chr3_+_38029462 6.72 ENST00000283713.6
VILL
villin-like
chr22_-_24096562 6.64 ENST00000398465.3
VPREB3
pre-B lymphocyte 3
chr1_-_9148495 6.64 ENST00000464985.1
ENST00000487835.1
ENST00000486632.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr6_-_30640811 6.64 ENST00000376442.3
DHX16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr1_+_144146808 6.61 ENST00000369190.5
ENST00000412624.2
ENST00000369365.3
NBPF8
neuroblastoma breakpoint family, member 8
chr9_+_42671887 6.57 ENST00000456520.1
ENST00000377391.3
CBWD7
COBW domain containing 7
chr5_+_172386419 6.54 ENST00000265100.2
ENST00000519239.1
RPL26L1
ribosomal protein L26-like 1
chr7_-_102184083 6.45 ENST00000379357.5
POLR2J3
polymerase (RNA) II (DNA directed) polypeptide J3
chr19_+_6361440 6.44 ENST00000245816.4
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr17_+_8191815 6.42 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RANGRF
RAN guanine nucleotide release factor
chr19_+_48828582 6.39 ENST00000270221.6
ENST00000596315.1
EMP3
epithelial membrane protein 3
chr19_+_23299777 6.36 ENST00000597761.2
ZNF730
zinc finger protein 730
chr1_+_28562617 6.36 ENST00000497986.1
ENST00000335514.5
ENST00000468425.2
ENST00000465645.1
ATPIF1
ATPase inhibitory factor 1
chr11_+_64863587 6.34 ENST00000530773.1
ENST00000279281.3
ENST00000529180.1
VPS51
vacuolar protein sorting 51 homolog (S. cerevisiae)
chr12_-_109027643 6.34 ENST00000388962.3
ENST00000550948.1
SELPLG
selectin P ligand
chr1_+_45212051 6.33 ENST00000372222.3
KIF2C
kinesin family member 2C
chr22_+_40742497 6.33 ENST00000216194.7
ADSL
adenylosuccinate lyase
chr7_-_72722783 6.33 ENST00000428206.1
ENST00000252594.6
ENST00000310326.8
ENST00000438747.2
NSUN5
NOP2/Sun domain family, member 5
chr6_+_16129308 6.27 ENST00000356840.3
ENST00000349606.4
MYLIP
myosin regulatory light chain interacting protein
chr14_-_23285011 6.22 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr16_+_29690358 6.22 ENST00000395384.4
ENST00000562473.1
QPRT
quinolinate phosphoribosyltransferase
chr20_+_361261 6.18 ENST00000217233.3
TRIB3
tribbles pseudokinase 3
chr7_-_102283238 6.18 ENST00000340457.8
UPK3BL
uroplakin 3B-like
chr11_+_10772534 6.18 ENST00000361367.2
CTR9
CTR9, Paf1/RNA polymerase II complex component
chr16_+_29467127 6.15 ENST00000344620.6
SULT1A4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr1_-_154580616 6.11 ENST00000368474.4
ADAR
adenosine deaminase, RNA-specific
chr16_-_28634874 6.11 ENST00000395609.1
ENST00000350842.4
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr11_+_65647280 6.09 ENST00000307886.3
ENST00000528419.1
ENST00000526034.1
CTSW
cathepsin W
chr12_-_8025623 6.07 ENST00000542782.1
ENST00000396589.2
ENST00000535266.1
ENST00000542505.1
SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14
chr2_-_62115659 6.02 ENST00000544185.1
CCT4
chaperonin containing TCP1, subunit 4 (delta)
chr17_-_8113886 6.01 ENST00000577833.1
ENST00000534871.1
ENST00000583915.1
ENST00000316199.6
ENST00000581511.1
ENST00000585124.1
AURKB
aurora kinase B
chr16_-_68033356 6.01 ENST00000393847.1
ENST00000573808.1
ENST00000572624.1
DPEP2
dipeptidase 2
chr16_+_88869621 5.98 ENST00000301019.4
CDT1
chromatin licensing and DNA replication factor 1
chr19_+_5690207 5.97 ENST00000347512.3
RPL36
ribosomal protein L36
chr2_+_219110149 5.95 ENST00000456575.1
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr6_+_139456226 5.93 ENST00000367658.2
HECA
headcase homolog (Drosophila)
chr12_-_14721283 5.93 ENST00000240617.5
PLBD1
phospholipase B domain containing 1
chr10_+_71029740 5.84 ENST00000450646.1
ENST00000360289.2
ENST00000448642.2
HK1
hexokinase 1
chr19_-_45953983 5.83 ENST00000592083.1
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr12_-_118797475 5.77 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3
TAO kinase 3
chr3_-_47517302 5.74 ENST00000441517.2
ENST00000545718.1
SCAP
SREBF chaperone
chr12_-_53601055 5.70 ENST00000552972.1
ENST00000422257.3
ENST00000267082.5
ITGB7
integrin, beta 7
chr16_-_29499154 5.69 ENST00000354563.5
RP11-231C14.4
Uncharacterized protein
chr12_-_6677422 5.69 ENST00000382421.3
ENST00000545200.1
ENST00000399466.2
ENST00000536124.1
ENST00000540228.1
ENST00000542867.1
ENST00000545492.1
ENST00000322166.5
ENST00000545915.1
NOP2
NOP2 nucleolar protein
chr4_+_2627159 5.68 ENST00000382839.3
ENST00000324666.5
ENST00000545951.1
ENST00000502458.1
ENST00000505311.1
FAM193A
family with sequence similarity 193, member A
chr19_+_22235310 5.66 ENST00000600162.1
ZNF257
zinc finger protein 257
chr6_-_31510181 5.63 ENST00000458640.1
ENST00000396172.1
ENST00000417556.2
DDX39B
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr20_+_3869423 5.63 ENST00000497424.1
PANK2
pantothenate kinase 2
chr1_-_40042416 5.62 ENST00000372857.3
ENST00000372856.3
ENST00000531243.2
ENST00000451091.2
PABPC4
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr22_+_40742512 5.61 ENST00000454266.2
ENST00000342312.6
ADSL
adenylosuccinate lyase
chr12_+_54891495 5.57 ENST00000293373.6
NCKAP1L
NCK-associated protein 1-like
chr7_-_102232891 5.54 ENST00000514917.2
RP11-514P8.7
RP11-514P8.7
chr1_+_144811744 5.52 ENST00000338347.4
ENST00000440491.2
ENST00000375552.4
NBPF9
neuroblastoma breakpoint family, member 9
chr2_-_74692473 5.51 ENST00000535045.1
ENST00000409065.1
ENST00000414701.1
ENST00000448666.1
ENST00000233616.4
ENST00000452063.2
MOGS
mannosyl-oligosaccharide glucosidase
chr2_+_39005325 5.51 ENST00000281950.3
GEMIN6
gem (nuclear organelle) associated protein 6
chr19_-_10305752 5.50 ENST00000540357.1
ENST00000359526.4
ENST00000340748.4
DNMT1
DNA (cytosine-5-)-methyltransferase 1
chr16_+_85832146 5.50 ENST00000565078.1
COX4I1
cytochrome c oxidase subunit IV isoform 1
chr1_-_11115877 5.50 ENST00000490101.1
SRM
spermidine synthase
chr13_+_25670268 5.49 ENST00000281589.3
PABPC3
poly(A) binding protein, cytoplasmic 3
chrX_-_71497148 5.49 ENST00000316084.6
RPS4X
ribosomal protein S4, X-linked
chr17_+_41158742 5.48 ENST00000415816.2
ENST00000438323.2
IFI35
interferon-induced protein 35
chr6_-_41909561 5.46 ENST00000372991.4
CCND3
cyclin D3
chr11_-_67211263 5.46 ENST00000393893.1
CORO1B
coronin, actin binding protein, 1B
chr12_+_7055631 5.44 ENST00000543115.1
ENST00000399448.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr3_+_112051347 5.41 ENST00000606471.1
CD200
CD200 molecule
chr19_+_52932435 5.38 ENST00000301085.4
ZNF534
zinc finger protein 534
chr6_+_32938665 5.38 ENST00000374831.4
ENST00000395289.2
BRD2
bromodomain containing 2
chr7_+_66386204 5.37 ENST00000341567.4
ENST00000607045.1
TMEM248
transmembrane protein 248
chr5_+_118691706 5.36 ENST00000415806.2
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr19_+_54704610 5.33 ENST00000302907.4
RPS9
ribosomal protein S9
chr7_-_76247617 5.30 ENST00000441393.1
POMZP3
POM121 and ZP3 fusion
chr15_+_78832747 5.29 ENST00000560217.1
ENST00000044462.7
ENST00000559082.1
ENST00000559948.1
ENST00000413382.2
ENST00000559146.1
ENST00000558281.1
PSMA4
proteasome (prosome, macropain) subunit, alpha type, 4
chr19_+_50321528 5.28 ENST00000312865.6
ENST00000595185.1
ENST00000538643.1
MED25
mediator complex subunit 25
chr19_-_36399149 5.28 ENST00000585901.2
ENST00000544690.2
ENST00000424586.3
ENST00000262629.4
ENST00000589517.1
TYROBP
TYRO protein tyrosine kinase binding protein
chr3_+_52448539 5.26 ENST00000461861.1
PHF7
PHD finger protein 7
chr10_-_30638090 5.24 ENST00000421701.1
ENST00000263063.4
MTPAP
mitochondrial poly(A) polymerase
chr19_+_36027660 5.24 ENST00000585510.1
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr14_+_21249200 5.24 ENST00000304677.2
RNASE6
ribonuclease, RNase A family, k6
chr5_+_32531893 5.23 ENST00000512913.1
SUB1
SUB1 homolog (S. cerevisiae)
chr4_-_24586140 5.19 ENST00000336812.4
DHX15
DEAH (Asp-Glu-Ala-His) box helicase 15
chr19_+_17862274 5.19 ENST00000596536.1
ENST00000593870.1
ENST00000598086.1
ENST00000598932.1
ENST00000595023.1
ENST00000594068.1
ENST00000596507.1
ENST00000595033.1
ENST00000597718.1
FCHO1
FCH domain only 1
chr5_-_140013275 5.18 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14
CD14 molecule
chr3_+_186739636 5.18 ENST00000440338.1
ENST00000448044.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr19_-_14889349 5.18 ENST00000315576.3
ENST00000392967.2
ENST00000346057.1
ENST00000353876.1
ENST00000353005.1
EMR2
egf-like module containing, mucin-like, hormone receptor-like 2
chr13_+_98612446 5.16 ENST00000496368.1
ENST00000421861.2
ENST00000357602.3
IPO5
importin 5
chr1_-_148347506 5.15 ENST00000369189.3
NBPF20
neuroblastoma breakpoint family, member 20

Network of associatons between targets according to the STRING database.

First level regulatory network of PITX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 15.6 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
4.9 34.3 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
4.9 9.8 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
4.6 18.4 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) actin polymerization-dependent cell motility(GO:0070358)
4.3 13.0 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
4.1 12.3 GO:2000397 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
4.0 11.9 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
3.7 11.2 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
3.3 13.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
3.0 21.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
3.0 18.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
2.8 17.0 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
2.8 11.3 GO:0036034 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
2.8 16.9 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
2.8 36.4 GO:0045059 positive thymic T cell selection(GO:0045059)
2.6 12.9 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
2.5 7.5 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812) positive regulation of mast cell cytokine production(GO:0032765) mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
2.4 9.5 GO:0033277 abortive mitotic cell cycle(GO:0033277)
2.4 7.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
2.3 14.0 GO:0045903 positive regulation of translational fidelity(GO:0045903)
2.3 22.5 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
2.1 8.5 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
2.1 6.3 GO:0050902 leukocyte adhesive activation(GO:0050902)
2.1 10.3 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
2.0 6.1 GO:1900368 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
2.0 6.0 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
2.0 23.8 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
1.9 11.6 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
1.9 13.3 GO:0015755 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
1.8 16.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
1.7 1.7 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
1.7 17.1 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
1.7 17.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.7 10.2 GO:0035803 egg coat formation(GO:0035803)
1.7 8.4 GO:0007619 courtship behavior(GO:0007619)
1.7 10.0 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
1.6 4.9 GO:0033364 mast cell secretory granule organization(GO:0033364)
1.6 6.4 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
1.6 12.5 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
1.5 4.6 GO:0035915 pore formation in membrane of other organism(GO:0035915)
1.5 13.6 GO:1901977 negative regulation of cell cycle checkpoint(GO:1901977) negative regulation of DNA damage checkpoint(GO:2000002)
1.5 1.5 GO:2001020 regulation of response to DNA damage stimulus(GO:2001020)
1.5 37.2 GO:0006337 nucleosome disassembly(GO:0006337)
1.5 4.4 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
1.4 10.1 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
1.4 5.7 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
1.4 14.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
1.4 2.8 GO:1902661 negative regulation of histone H3-K9 dimethylation(GO:1900110) positive regulation of glucose mediated signaling pathway(GO:1902661)
1.4 41.8 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
1.4 4.1 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
1.4 10.9 GO:0070475 rRNA base methylation(GO:0070475)
1.4 18.9 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
1.3 4.0 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
1.3 8.0 GO:0042780 tRNA 3'-end processing(GO:0042780)
1.3 2.6 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
1.3 6.5 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
1.3 5.2 GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
1.3 8.9 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
1.2 5.0 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
1.2 6.2 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
1.2 5.0 GO:0021796 cerebral cortex regionalization(GO:0021796)
1.2 2.5 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
1.2 7.4 GO:0032621 interleukin-18 production(GO:0032621)
1.2 6.0 GO:0045914 negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
1.2 3.6 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
1.2 4.7 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
1.2 8.1 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
1.1 3.4 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
1.1 7.8 GO:0008295 spermidine biosynthetic process(GO:0008295)
1.1 6.6 GO:0006741 NADP biosynthetic process(GO:0006741)
1.1 13.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
1.1 3.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
1.1 2.1 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
1.1 51.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
1.0 10.3 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
1.0 3.1 GO:0006447 regulation of translational initiation by iron(GO:0006447)
1.0 21.4 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
1.0 4.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
1.0 8.6 GO:0001878 response to yeast(GO:0001878)
1.0 2.9 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
1.0 2.9 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.9 9.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.9 17.8 GO:0032060 bleb assembly(GO:0032060)
0.9 7.4 GO:1903599 positive regulation of mitophagy(GO:1903599)
0.9 2.7 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.9 2.7 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.9 28.0 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.9 6.3 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.9 4.5 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.9 10.5 GO:0006089 lactate metabolic process(GO:0006089)
0.9 2.6 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.8 2.5 GO:2000670 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.8 4.2 GO:2000110 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) negative regulation of macrophage apoptotic process(GO:2000110)
0.8 3.3 GO:0043248 proteasome assembly(GO:0043248)
0.8 5.8 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.8 2.5 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.8 5.7 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.8 4.0 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.8 2.4 GO:0002352 B cell selection(GO:0002339) B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.8 44.0 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.8 7.2 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.8 0.8 GO:0002316 follicular B cell differentiation(GO:0002316)
0.8 14.2 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.8 4.7 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.8 2.3 GO:0051037 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.8 3.1 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.8 6.9 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.8 3.0 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.8 2.3 GO:0072229 isoleucine catabolic process(GO:0006550) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.8 2.3 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.7 3.7 GO:0033384 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.7 2.2 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.7 3.0 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.7 2.2 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.7 5.9 GO:0032790 ribosome disassembly(GO:0032790)
0.7 22.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.7 2.2 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
0.7 0.7 GO:0090662 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.7 2.9 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.7 2.2 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.7 9.4 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.7 2.2 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.7 27.0 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.7 5.6 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.7 4.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.7 2.1 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.7 1.3 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.7 4.6 GO:0006772 thiamine metabolic process(GO:0006772)
0.7 7.3 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.7 2.6 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.7 3.9 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.7 42.7 GO:0002279 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.6 3.8 GO:0006642 triglyceride mobilization(GO:0006642)
0.6 3.8 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.6 10.0 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.6 5.6 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.6 5.0 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.6 5.0 GO:0006116 NADH oxidation(GO:0006116)
0.6 6.7 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.6 1.8 GO:0072719 cellular response to cisplatin(GO:0072719)
0.6 53.2 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.6 2.4 GO:0070982 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.6 10.7 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.6 1.8 GO:0009183 purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183) dGDP metabolic process(GO:0046066)
0.6 10.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.6 3.5 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.6 2.3 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.6 7.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.6 2.9 GO:0003051 brain renin-angiotensin system(GO:0002035) angiotensin-mediated drinking behavior(GO:0003051)
0.6 33.4 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.6 1.7 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.6 5.0 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.5 15.8 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.5 4.3 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.5 1.6 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.5 1.6 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.5 21.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.5 77.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.5 5.9 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.5 5.3 GO:0001973 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.5 4.7 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.5 2.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.5 2.6 GO:0098502 DNA dephosphorylation(GO:0098502)
0.5 9.2 GO:0072540 T-helper cell lineage commitment(GO:0002295) T-helper 17 cell lineage commitment(GO:0072540)
0.5 4.5 GO:0051014 actin filament severing(GO:0051014)
0.5 2.5 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.5 2.5 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.5 1.5 GO:0034127 regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034127)
0.5 1.4 GO:0046368 GDP-L-fucose biosynthetic process(GO:0042350) 'de novo' GDP-L-fucose biosynthetic process(GO:0042351) GDP-L-fucose metabolic process(GO:0046368)
0.5 1.9 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.5 1.9 GO:0016139 glycoside catabolic process(GO:0016139) glycosylceramide catabolic process(GO:0046477)
0.5 15.9 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.5 21.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.5 4.6 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.5 2.3 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.5 6.5 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.5 11.0 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.5 1.4 GO:0006059 hexitol metabolic process(GO:0006059)
0.5 1.8 GO:0042631 cellular response to water deprivation(GO:0042631)
0.4 1.3 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.4 2.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.4 10.2 GO:0051194 positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.4 3.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.4 4.0 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.4 2.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.4 4.3 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.4 3.9 GO:0060754 regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754)
0.4 3.0 GO:0007519 skeletal muscle tissue development(GO:0007519) skeletal muscle organ development(GO:0060538)
0.4 3.9 GO:0046689 response to mercury ion(GO:0046689)
0.4 3.0 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.4 4.6 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.4 2.1 GO:0048539 bone marrow development(GO:0048539)
0.4 1.3 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.4 3.6 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.4 0.8 GO:0006788 heme oxidation(GO:0006788)
0.4 8.8 GO:0097186 amelogenesis(GO:0097186)
0.4 7.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.4 1.2 GO:0044805 late nucleophagy(GO:0044805)
0.4 2.3 GO:0015693 magnesium ion transport(GO:0015693)
0.4 2.3 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.4 2.3 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.4 10.6 GO:0000042 protein targeting to Golgi(GO:0000042)
0.4 4.5 GO:0016236 macroautophagy(GO:0016236)
0.4 1.1 GO:1990910 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) response to hypobaric hypoxia(GO:1990910)
0.4 7.8 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.4 5.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.4 4.8 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.4 7.7 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.4 8.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.3 2.4 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.3 24.7 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.3 1.7 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.3 4.1 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.3 1.4 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.3 6.1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.3 1.3 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.3 3.3 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.3 3.9 GO:0032042 mitochondrial DNA metabolic process(GO:0032042)
0.3 1.3 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.3 1.9 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.3 7.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.3 3.1 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
0.3 3.0 GO:0042262 DNA protection(GO:0042262)
0.3 4.2 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.3 0.3 GO:0051031 tRNA transport(GO:0051031)
0.3 3.6 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.3 5.6 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.3 2.4 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.3 2.4 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.3 3.2 GO:0051601 exocyst localization(GO:0051601)
0.3 12.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.3 2.8 GO:0042373 vitamin K metabolic process(GO:0042373)
0.3 3.0 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.3 3.7 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.3 1.0 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.3 5.4 GO:0097320 membrane tubulation(GO:0097320)
0.3 0.8 GO:0043605 cellular amide catabolic process(GO:0043605)
0.3 3.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.3 1.3 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.2 2.2 GO:0009249 protein lipoylation(GO:0009249)
0.2 2.5 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.2 10.1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.2 4.6 GO:0002643 regulation of tolerance induction(GO:0002643)
0.2 0.5 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.2 0.9 GO:1904796 regulation of core promoter binding(GO:1904796)
0.2 17.5 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 1.6 GO:1902969 mitotic DNA replication(GO:1902969)
0.2 0.7 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.2 2.8 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.2 2.7 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086) positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.2 2.5 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 3.9 GO:0035641 locomotory exploration behavior(GO:0035641)
0.2 4.3 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.2 0.5 GO:0015743 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.2 3.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.2 2.0 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.2 1.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.2 1.9 GO:0051085 'de novo' posttranslational protein folding(GO:0051084) chaperone mediated protein folding requiring cofactor(GO:0051085)
0.2 0.9 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.2 0.9 GO:0070245 snRNA transcription from RNA polymerase III promoter(GO:0042796) positive regulation of thymocyte apoptotic process(GO:0070245)
0.2 1.7 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.2 10.3 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.2 2.9 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.2 3.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 0.2 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.2 0.8 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.2 57.0 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.2 1.4 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.2 4.3 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.2 3.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 0.4 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.2 0.4 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.2 19.3 GO:0034728 nucleosome organization(GO:0034728)
0.2 0.9 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.2 1.6 GO:0072520 seminiferous tubule development(GO:0072520)
0.2 2.8 GO:0007220 Notch receptor processing(GO:0007220)
0.2 5.4 GO:0043068 positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.2 1.2 GO:0016180 snRNA processing(GO:0016180)
0.2 0.9 GO:1903911 positive regulation of receptor clustering(GO:1903911)
0.2 3.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 4.7 GO:0001881 receptor recycling(GO:0001881)
0.2 1.9 GO:0048003 antigen processing and presentation via MHC class Ib(GO:0002475) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.2 2.6 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.2 1.4 GO:1904646 cellular response to beta-amyloid(GO:1904646)
0.2 1.9 GO:0044065 regulation of respiratory system process(GO:0044065)
0.2 0.5 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.1 0.9 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.6 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 5.3 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.1 2.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 3.9 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 3.7 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 3.7 GO:0034383 low-density lipoprotein particle clearance(GO:0034383)
0.1 1.4 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.1 1.1 GO:0045047 protein targeting to ER(GO:0045047)
0.1 0.5 GO:0000023 maltose metabolic process(GO:0000023)
0.1 1.4 GO:0042940 D-amino acid transport(GO:0042940)
0.1 1.2 GO:0030916 otic vesicle formation(GO:0030916)
0.1 1.1 GO:0015816 glycine transport(GO:0015816)
0.1 1.0 GO:0010624 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.1 1.3 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1 2.3 GO:0032418 lysosome localization(GO:0032418)
0.1 4.1 GO:0032527 protein exit from endoplasmic reticulum(GO:0032527)
0.1 0.6 GO:0007635 chemosensory behavior(GO:0007635)
0.1 1.5 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 3.8 GO:0032508 DNA duplex unwinding(GO:0032508)
0.1 3.7 GO:0030261 chromosome condensation(GO:0030261)
0.1 9.8 GO:0016575 histone deacetylation(GO:0016575)
0.1 1.3 GO:0016050 vesicle organization(GO:0016050)
0.1 3.6 GO:0050832 defense response to fungus(GO:0050832)
0.1 0.6 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.5 GO:0048840 otolith development(GO:0048840)
0.1 8.4 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.1 1.9 GO:0097421 liver regeneration(GO:0097421)
0.1 0.1 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.1 1.5 GO:0014029 neural crest formation(GO:0014029)
0.1 1.2 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 0.9 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 3.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.6 GO:0035799 ureter maturation(GO:0035799)
0.1 3.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.1 0.7 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 14.0 GO:0006401 RNA catabolic process(GO:0006401)
0.1 1.4 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 2.0 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.1 1.8 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.1 0.6 GO:0031648 protein destabilization(GO:0031648)
0.1 0.4 GO:1905247 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.1 0.2 GO:0042255 ribosome assembly(GO:0042255)
0.1 5.4 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.1 1.2 GO:0001701 in utero embryonic development(GO:0001701)
0.1 2.1 GO:0007140 male meiosis(GO:0007140)
0.1 1.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.4 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.1 0.5 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 2.1 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.1 3.1 GO:0030890 positive regulation of B cell proliferation(GO:0030890)
0.1 1.6 GO:0005513 detection of calcium ion(GO:0005513)
0.1 1.0 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) protein O-linked fucosylation(GO:0036066)
0.1 0.6 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.6 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 2.0 GO:0006833 water transport(GO:0006833)
0.1 0.3 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 1.5 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.1 2.1 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.1 4.7 GO:0050871 positive regulation of B cell activation(GO:0050871)
0.1 2.4 GO:0001504 neurotransmitter uptake(GO:0001504)
0.1 8.1 GO:0002377 immunoglobulin production(GO:0002377)
0.1 1.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 2.7 GO:0000060 protein import into nucleus, translocation(GO:0000060)
0.1 0.8 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 2.6 GO:0032456 endocytic recycling(GO:0032456)
0.1 0.3 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.8 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.1 1.2 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.3 GO:0090527 actin filament reorganization(GO:0090527)
0.1 1.9 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.7 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.1 1.0 GO:0006020 inositol metabolic process(GO:0006020)
0.1 1.8 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 1.8 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 3.9 GO:0030183 B cell differentiation(GO:0030183)
0.1 4.7 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 1.6 GO:0048753 melanosome organization(GO:0032438) pigment granule organization(GO:0048753)
0.1 1.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 2.1 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 1.6 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.1 5.1 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.1 2.5 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.1 1.2 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 4.5 GO:0007286 spermatid development(GO:0007286)
0.1 1.4 GO:0043171 peptide catabolic process(GO:0043171)
0.1 0.6 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.4 GO:0018212 peptidyl-tyrosine phosphorylation(GO:0018108) peptidyl-tyrosine modification(GO:0018212)
0.1 0.2 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.2 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 1.4 GO:0006625 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1 0.8 GO:0016578 histone deubiquitination(GO:0016578)
0.1 0.3 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1 0.6 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 1.5 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.1 1.0 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 0.6 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.0 3.7 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.7 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 1.1 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.4 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.3 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.3 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.7 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 3.3 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 2.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 1.1 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.0 0.4 GO:0030225 macrophage differentiation(GO:0030225)
0.0 1.7 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.0 0.6 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.3 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 2.2 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.6 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.4 GO:0015671 gas transport(GO:0015669) oxygen transport(GO:0015671)
0.0 0.3 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.7 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 1.4 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.8 GO:0008380 RNA splicing(GO:0008380)
0.0 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.9 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0000076 DNA replication checkpoint(GO:0000076)
0.0 0.1 GO:0046108 uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
0.0 0.5 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.8 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.4 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.3 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309)
0.0 0.6 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.1 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 4.1 GO:0007050 cell cycle arrest(GO:0007050)
0.0 2.1 GO:0046546 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 0.2 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.2 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 1.0 GO:0030218 erythrocyte differentiation(GO:0030218)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 4.3 GO:0007283 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 1.1 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.0 0.7 GO:0046324 regulation of glucose import(GO:0046324)
0.0 0.3 GO:0006414 translational elongation(GO:0006414)
0.0 1.7 GO:0000209 protein polyubiquitination(GO:0000209)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 14.9 GO:0030289 protein phosphatase 4 complex(GO:0030289)
4.2 46.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
3.4 20.2 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
3.3 9.8 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
2.7 35.7 GO:0000243 commitment complex(GO:0000243)
2.5 12.6 GO:0034715 pICln-Sm protein complex(GO:0034715)
2.4 4.9 GO:0002081 outer acrosomal membrane(GO:0002081)
2.3 11.7 GO:0032021 NELF complex(GO:0032021)
2.3 28.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
2.0 22.2 GO:0005687 U4 snRNP(GO:0005687)
2.0 5.9 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
1.9 13.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
1.9 22.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
1.8 12.3 GO:0000813 ESCRT I complex(GO:0000813)
1.7 22.3 GO:0042555 MCM complex(GO:0042555)
1.7 5.0 GO:0002079 inner acrosomal membrane(GO:0002079)
1.7 11.6 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
1.6 6.3 GO:1990745 EARP complex(GO:1990745)
1.6 12.4 GO:0034719 SMN-Sm protein complex(GO:0034719) Gemini of coiled bodies(GO:0097504)
1.5 19.8 GO:0002199 zona pellucida receptor complex(GO:0002199)
1.5 7.4 GO:1990037 Lewy body core(GO:1990037)
1.4 26.0 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
1.4 5.7 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
1.4 15.4 GO:0070531 BRCA1-A complex(GO:0070531)
1.4 28.9 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
1.4 21.9 GO:0097431 mitotic spindle pole(GO:0097431)
1.4 4.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
1.3 6.7 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
1.3 18.4 GO:0031209 SCAR complex(GO:0031209)
1.3 6.4 GO:0009368 endopeptidase Clp complex(GO:0009368)
1.3 5.0 GO:0055087 Ski complex(GO:0055087)
1.3 37.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
1.2 6.0 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
1.2 8.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
1.1 7.9 GO:0036021 endolysosome lumen(GO:0036021)
1.1 8.5 GO:0097539 ciliary transition fiber(GO:0097539)
1.1 38.9 GO:0042629 mast cell granule(GO:0042629)
1.0 5.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
1.0 7.2 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
1.0 5.1 GO:0044530 supraspliceosomal complex(GO:0044530)
1.0 20.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.9 8.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.9 20.9 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.9 65.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.9 12.1 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.9 7.8 GO:0061574 ASAP complex(GO:0061574)
0.9 13.7 GO:0031080 nuclear pore outer ring(GO:0031080)
0.8 5.8 GO:0032133 chromosome passenger complex(GO:0032133)
0.8 5.7 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.8 9.5 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.8 14.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.8 6.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.8 8.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.7 9.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.7 4.5 GO:0072589 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.7 0.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.7 9.9 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.7 5.5 GO:0070761 pre-snoRNP complex(GO:0070761)
0.7 7.5 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.7 13.7 GO:0005839 proteasome core complex(GO:0005839)
0.6 3.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.6 19.3 GO:0005838 proteasome regulatory particle(GO:0005838)
0.6 63.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.6 1.7 GO:0033150 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.6 2.9 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.6 17.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.6 3.4 GO:0070545 PeBoW complex(GO:0070545)
0.5 13.0 GO:0035371 microtubule plus-end(GO:0035371)
0.5 1.6 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.5 1.6 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.5 6.8 GO:0016461 unconventional myosin complex(GO:0016461)
0.5 4.0 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.5 2.4 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.5 2.4 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.5 1.9 GO:0044611 nuclear pore inner ring(GO:0044611)
0.5 5.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.5 3.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.5 18.8 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.5 2.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.5 1.8 GO:0061700 GATOR2 complex(GO:0061700)
0.4 2.2 GO:0030061 mitochondrial crista(GO:0030061)
0.4 3.4 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.4 7.7 GO:0001891 phagocytic cup(GO:0001891)
0.4 13.2 GO:0005719 nuclear euchromatin(GO:0005719)
0.4 9.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.4 2.4 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.4 4.7 GO:0033093 Weibel-Palade body(GO:0033093)
0.4 6.7 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.4 3.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.4 1.9 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.4 2.5 GO:0042788 polysomal ribosome(GO:0042788)
0.3 1.0 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.3 3.7 GO:0070765 gamma-secretase complex(GO:0070765)
0.3 8.7 GO:0016514 SWI/SNF complex(GO:0016514)
0.3 6.0 GO:0031083 BLOC-1 complex(GO:0031083)
0.3 7.3 GO:0000145 exocyst(GO:0000145)
0.3 5.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.3 2.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.3 2.8 GO:0005833 hemoglobin complex(GO:0005833)
0.3 2.1 GO:0005787 signal peptidase complex(GO:0005787)
0.3 6.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.3 3.7 GO:0001673 male germ cell nucleus(GO:0001673)
0.3 1.4 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.3 4.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.3 3.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.3 2.1 GO:0032010 phagolysosome(GO:0032010)
0.3 3.4 GO:0044754 autolysosome(GO:0044754)
0.3 1.0 GO:0000811 GINS complex(GO:0000811)
0.2 2.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2 4.5 GO:0002080 acrosomal membrane(GO:0002080)
0.2 5.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 23.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.2 14.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 15.0 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.2 13.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 2.6 GO:0005642 annulate lamellae(GO:0005642)
0.2 16.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.2 12.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 5.2 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.2 4.0 GO:0097228 sperm principal piece(GO:0097228)
0.2 20.1 GO:0070821 tertiary granule membrane(GO:0070821)
0.2 2.0 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2 25.3 GO:0000922 spindle pole(GO:0000922)
0.2 31.1 GO:0005681 spliceosomal complex(GO:0005681)
0.2 3.3 GO:0030904 retromer complex(GO:0030904)
0.2 1.3 GO:0072687 meiotic spindle(GO:0072687)
0.2 4.6 GO:0005876 spindle microtubule(GO:0005876)
0.2 3.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 9.1 GO:0035579 specific granule membrane(GO:0035579)
0.2 5.5 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.2 19.7 GO:0016605 PML body(GO:0016605)
0.2 3.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.2 1.7 GO:0030008 TRAPP complex(GO:0030008)
0.2 0.6 GO:0031941 filamentous actin(GO:0031941)
0.1 1.9 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 3.3 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 4.3 GO:0005921 gap junction(GO:0005921)
0.1 0.6 GO:0097513 myosin II filament(GO:0097513)
0.1 2.7 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 1.2 GO:0032039 integrator complex(GO:0032039)
0.1 0.9 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 10.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 5.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.8 GO:0070652 HAUS complex(GO:0070652)
0.1 0.4 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.3 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 3.8 GO:0045171 intercellular bridge(GO:0045171)
0.1 2.8 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 2.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 3.7 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.1 4.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 2.3 GO:0046930 pore complex(GO:0046930)
0.1 4.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 3.0 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 3.0 GO:0005859 muscle myosin complex(GO:0005859)
0.1 6.0 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.1 0.2 GO:0000799 nuclear condensin complex(GO:0000799)
0.1 2.3 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 11.6 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1 1.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 4.7 GO:0014704 intercalated disc(GO:0014704)
0.1 0.3 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 1.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 2.9 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 9.1 GO:0005923 bicellular tight junction(GO:0005923)
0.1 2.9 GO:0000786 nucleosome(GO:0000786)
0.1 2.4 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.1 3.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 3.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 10.3 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 19.2 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 2.3 GO:0030315 T-tubule(GO:0030315)
0.1 7.6 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.1 1.9 GO:0005840 ribosome(GO:0005840)
0.1 9.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 7.1 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 3.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 3.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.3 GO:0015030 Cajal body(GO:0015030)
0.0 0.5 GO:0031105 septin complex(GO:0031105)
0.0 1.9 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.1 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 5.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 1.1 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.0 GO:0005643 nuclear pore(GO:0005643)
0.0 2.2 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.2 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.4 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 1.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 1.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.2 GO:0005903 brush border(GO:0005903)
0.0 4.2 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.5 GO:0015629 actin cytoskeleton(GO:0015629)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 34.3 GO:0047685 amine sulfotransferase activity(GO:0047685)
5.2 15.6 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
4.9 9.8 GO:0004832 valine-tRNA ligase activity(GO:0004832)
4.3 13.0 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
3.4 10.3 GO:0004913 interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917)
3.0 9.0 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
2.9 20.2 GO:0030369 ICAM-3 receptor activity(GO:0030369)
2.8 28.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
2.7 45.8 GO:0004062 aryl sulfotransferase activity(GO:0004062)
2.7 21.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
2.6 28.9 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
2.5 17.5 GO:0030621 U4 snRNA binding(GO:0030621)
2.5 17.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
2.5 9.8 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
2.4 7.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
2.2 8.9 GO:0016936 galactoside binding(GO:0016936)
2.2 6.6 GO:0003953 NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
2.1 14.9 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
2.1 21.3 GO:1990446 U1 snRNP binding(GO:1990446)
2.1 6.4 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
2.1 8.4 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
2.1 6.2 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
2.0 7.8 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
1.9 15.5 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
1.9 5.7 GO:0004766 spermidine synthase activity(GO:0004766)
1.9 13.3 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
1.9 5.7 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
1.9 5.6 GO:0017130 poly(C) RNA binding(GO:0017130)
1.7 5.2 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
1.7 17.4 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
1.7 5.2 GO:0016019 peptidoglycan receptor activity(GO:0016019)
1.7 5.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
1.7 5.2 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
1.7 5.0 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
1.5 17.0 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
1.5 21.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
1.5 31.9 GO:0001055 RNA polymerase II activity(GO:0001055)
1.5 10.5 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
1.5 14.9 GO:0019237 centromeric DNA binding(GO:0019237)
1.5 5.8 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
1.4 11.6 GO:1990763 arrestin family protein binding(GO:1990763)
1.4 5.6 GO:0004594 pantothenate kinase activity(GO:0004594)
1.3 10.8 GO:0016842 amidine-lyase activity(GO:0016842)
1.3 3.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
1.2 19.9 GO:0008494 translation activator activity(GO:0008494)
1.2 12.9 GO:0051525 NFAT protein binding(GO:0051525)
1.1 17.0 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
1.1 10.2 GO:0032190 acrosin binding(GO:0032190)
1.1 9.0 GO:1990932 5.8S rRNA binding(GO:1990932)
1.1 3.4 GO:0042134 rRNA primary transcript binding(GO:0042134)
1.1 7.5 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
1.0 7.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
1.0 3.0 GO:0004802 transketolase activity(GO:0004802)
1.0 10.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.9 7.5 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.9 25.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.9 18.5 GO:0050786 RAGE receptor binding(GO:0050786)
0.9 7.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.9 7.4 GO:1901612 cardiolipin binding(GO:1901612)
0.9 5.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.9 27.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.9 4.4 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.9 14.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.9 6.0 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.8 2.5 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.8 13.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.8 45.6 GO:0042169 SH2 domain binding(GO:0042169)
0.8 17.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.8 6.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.8 2.3 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.8 3.8 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.7 3.7 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.7 2.2 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.7 4.5 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.7 2.2 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.7 5.8 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.7 4.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.7 30.5 GO:0017069 snRNA binding(GO:0017069)
0.7 2.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.7 14.3 GO:0070717 poly-purine tract binding(GO:0070717)
0.7 2.8 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.7 2.7 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.7 2.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.7 6.0 GO:0035174 histone serine kinase activity(GO:0035174)
0.6 5.2 GO:0008097 5S rRNA binding(GO:0008097)
0.6 3.9 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.6 2.6 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) polynucleotide phosphatase activity(GO:0098518)
0.6 2.6 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.6 28.3 GO:0050699 WW domain binding(GO:0050699)
0.6 10.5 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.6 6.7 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.6 3.0 GO:0030613 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.6 12.7 GO:0070628 proteasome binding(GO:0070628)
0.6 26.6 GO:0031369 translation initiation factor binding(GO:0031369)
0.6 3.6 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.6 1.7 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.6 4.0 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.6 2.3 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.6 113.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.5 22.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.5 22.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.5 14.6 GO:0003951 NAD+ kinase activity(GO:0003951)
0.5 3.0 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.5 5.4 GO:0015926 glucosidase activity(GO:0015926)
0.5 17.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.5 2.4 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.5 1.4 GO:0005124 scavenger receptor binding(GO:0005124)
0.5 2.4 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.5 2.9 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.5 1.9 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.5 3.3 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.5 0.5 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.5 47.5 GO:0043130 ubiquitin binding(GO:0043130)
0.5 1.4 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.4 4.9 GO:0042834 peptidoglycan binding(GO:0042834)
0.4 3.6 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.4 1.8 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.4 1.7 GO:0042296 ISG15 transferase activity(GO:0042296)
0.4 1.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.4 5.1 GO:0004519 endonuclease activity(GO:0004519)
0.4 9.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.4 1.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.4 2.5 GO:0070513 death domain binding(GO:0070513)
0.4 14.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.4 2.8 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.4 1.6 GO:0004335 galactokinase activity(GO:0004335)
0.4 1.9 GO:0002046 opsin binding(GO:0002046)
0.4 1.9 GO:0001594 trace-amine receptor activity(GO:0001594)
0.4 3.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.4 2.3 GO:0055103 ligase regulator activity(GO:0055103)
0.4 0.4 GO:0004461 lactose synthase activity(GO:0004461)
0.4 2.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.4 2.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.4 5.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.3 1.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.3 9.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.3 2.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.3 4.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.3 3.0 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.3 4.6 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.3 5.1 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.3 9.3 GO:0070063 RNA polymerase binding(GO:0070063)
0.3 1.7 GO:0039552 RIG-I binding(GO:0039552)
0.3 27.3 GO:0070035 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.3 1.4 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.3 4.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.3 0.8 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.3 3.7 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.3 2.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.3 2.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.3 1.0 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.3 3.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.2 2.4 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.2 2.6 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.2 2.9 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.2 0.9 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2 1.9 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 4.5 GO:0005537 mannose binding(GO:0005537)
0.2 6.1 GO:0042288 MHC class I protein binding(GO:0042288)
0.2 8.5 GO:0004532 exoribonuclease activity(GO:0004532)
0.2 6.8 GO:0046965 retinoid X receptor binding(GO:0046965)
0.2 1.8 GO:0004064 arylesterase activity(GO:0004064)
0.2 0.5 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.2 1.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.2 1.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.2 1.5 GO:0004849 uridine kinase activity(GO:0004849)
0.2 12.6 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.2 1.5 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 7.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.2 9.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 1.0 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.2 7.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.2 1.6 GO:0016778 diphosphotransferase activity(GO:0016778)
0.2 4.4 GO:0001968 fibronectin binding(GO:0001968)
0.2 2.8 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 0.6 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.2 5.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 8.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 4.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2 1.9 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.2 1.7 GO:0003993 acid phosphatase activity(GO:0003993)
0.2 2.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 2.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.2 8.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 9.5 GO:0005158 insulin receptor binding(GO:0005158)
0.2 7.8 GO:0000049 tRNA binding(GO:0000049)
0.2 1.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.2 5.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 15.1 GO:0030295 protein kinase activator activity(GO:0030295)
0.2 0.9 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.2 2.2 GO:0070034 telomerase RNA binding(GO:0070034)
0.2 3.1 GO:0004177 aminopeptidase activity(GO:0004177)
0.2 3.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 2.4 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.2 2.1 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.2 1.4 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.2 8.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 1.9 GO:0015929 hexosaminidase activity(GO:0015929)
0.2 3.0 GO:0097602 cullin family protein binding(GO:0097602)
0.2 4.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 4.8 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2 4.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 2.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 2.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.9 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 1.2 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 2.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 4.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 2.1 GO:0030515 snoRNA binding(GO:0030515)
0.1 2.2 GO:0015250 water channel activity(GO:0015250)
0.1 2.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 2.1 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.1 0.4 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 2.3 GO:0005522 profilin binding(GO:0005522)
0.1 0.9 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 14.2 GO:0042393 histone binding(GO:0042393)
0.1 1.0 GO:0035497 cAMP response element binding(GO:0035497)
0.1 39.9 GO:0003713 transcription coactivator activity(GO:0003713)
0.1 0.7 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 3.8 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 3.3 GO:0005521 lamin binding(GO:0005521)
0.1 5.1 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1 0.8 GO:0019209 kinase activator activity(GO:0019209)
0.1 3.4 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.1 1.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 2.4 GO:0031489 myosin V binding(GO:0031489)
0.1 0.3 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 6.4 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 0.5 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 5.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 0.2 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.1 2.4 GO:0005123 death receptor binding(GO:0005123)
0.1 1.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.3 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 1.5 GO:0051400 BH domain binding(GO:0051400)
0.1 1.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.9 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 4.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.4 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.1 3.2 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.1 0.4 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 2.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.4 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.1 0.4 GO:0050436 microfibril binding(GO:0050436)
0.1 0.9 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 6.3 GO:0001618 virus receptor activity(GO:0001618)
0.1 1.2 GO:0009881 photoreceptor activity(GO:0009881)
0.1 0.9 GO:0001848 complement binding(GO:0001848)
0.1 8.5 GO:0019903 protein phosphatase binding(GO:0019903)
0.1 1.5 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
0.1 0.3 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.8 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.1 1.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 3.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.6 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 1.0 GO:0005112 Notch binding(GO:0005112)
0.1 18.9 GO:0005096 GTPase activator activity(GO:0005096)
0.1 0.6 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467) decanoate--CoA ligase activity(GO:0102391)
0.1 1.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 3.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.6 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.3 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 1.0 GO:0043022 ribosome binding(GO:0043022)
0.0 1.4 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.4 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 1.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 0.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 4.6 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 2.0 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.1 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 0.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 4.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 15.4 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.8 GO:0002039 p53 binding(GO:0002039)
0.0 1.6 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 1.1 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 1.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.5 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 2.2 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.7 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 1.3 GO:0003682 chromatin binding(GO:0003682)
0.0 0.3 GO:0008374 O-acyltransferase activity(GO:0008374)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 0.8 ST GAQ PATHWAY G alpha q Pathway
0.7 39.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.7 24.3 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.7 30.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.6 27.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.6 25.9 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.5 7.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.5 17.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.5 7.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.5 37.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.4 14.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.4 10.3 PID EPO PATHWAY EPO signaling pathway
0.4 4.6 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.3 9.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.3 12.4 PID ATM PATHWAY ATM pathway
0.3 20.1 PID ATR PATHWAY ATR signaling pathway
0.3 9.5 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.3 3.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.2 4.8 PID IL23 PATHWAY IL23-mediated signaling events
0.2 2.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.2 4.3 PID AURORA A PATHWAY Aurora A signaling
0.2 14.6 PID AURORA B PATHWAY Aurora B signaling
0.2 15.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 7.0 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.2 9.6 SIG CHEMOTAXIS Genes related to chemotaxis
0.2 3.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 12.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 2.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2 4.8 PID BARD1 PATHWAY BARD1 signaling events
0.2 5.8 PID INSULIN PATHWAY Insulin Pathway
0.2 14.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.2 7.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.2 4.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 10.8 PID E2F PATHWAY E2F transcription factor network
0.1 4.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 3.4 PID CONE PATHWAY Visual signal transduction: Cones
0.1 3.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 5.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 4.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 4.4 PID FOXO PATHWAY FoxO family signaling
0.1 7.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 2.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 11.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 4.9 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 3.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 4.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 3.5 PID MYC PATHWAY C-MYC pathway
0.1 1.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 5.6 PID CDC42 PATHWAY CDC42 signaling events
0.1 4.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 4.0 PID BMP PATHWAY BMP receptor signaling
0.1 3.7 PID PLK1 PATHWAY PLK1 signaling events
0.1 2.6 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 4.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 2.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 2.5 PID TNF PATHWAY TNF receptor signaling pathway
0.1 1.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 0.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 1.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 1.8 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 1.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.6 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.1 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 2.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 2.3 PID P73PATHWAY p73 transcription factor network
0.0 2.4 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.4 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.7 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.8 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.0 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.2 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.5 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 80.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
1.7 39.9 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
1.5 23.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
1.3 86.1 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
1.3 31.1 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
1.2 12.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
1.1 30.8 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
1.0 17.8 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.9 8.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.9 70.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.9 32.9 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.8 17.2 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.8 71.9 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.8 7.9 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.8 13.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.7 14.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.7 22.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.7 11.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.7 6.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.6 14.8 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.6 85.7 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.6 9.9 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.5 6.0 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.5 7.6 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.5 14.1 REACTOME KINESINS Genes involved in Kinesins
0.5 11.1 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.5 20.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.5 13.8 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.5 11.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.5 43.8 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.5 5.2 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.5 2.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.5 11.6 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.4 8.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.4 5.9 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.4 10.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.4 8.4 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.4 7.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.3 13.1 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.3 7.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.3 25.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.3 5.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.3 6.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.3 3.0 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.3 13.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.3 4.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.3 8.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.3 4.9 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.3 4.0 REACTOME TRANSLATION Genes involved in Translation
0.2 2.7 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.2 3.7 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.2 2.9 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.2 16.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 5.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.2 5.6 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.2 41.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.2 3.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 6.1 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 2.0 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.2 3.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.2 5.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.2 3.8 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.2 6.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 4.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 7.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 4.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 0.8 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.2 2.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 16.5 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.1 9.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 3.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 2.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 5.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 4.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.4 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 1.2 REACTOME OPSINS Genes involved in Opsins
0.1 2.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 3.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 0.8 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 3.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 0.7 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 2.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 2.3 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.1 1.5 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.1 1.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 0.5 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.1 1.8 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 1.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 2.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 3.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.4 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.1 1.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.7 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 1.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.9 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.1 1.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.1 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 3.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 1.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 3.9 REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION Genes involved in Class I MHC mediated antigen processing & presentation
0.0 1.3 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.2 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen