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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for PITX3

Z-value: 2.06

Motif logo

Transcription factors associated with PITX3

Gene Symbol Gene ID Gene Info
ENSG00000107859.5 paired like homeodomain 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PITX3hg19_v2_chr10_-_104001231_104001274-0.695.7e-32Click!

Activity profile of PITX3 motif

Sorted Z-values of PITX3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_159848807 53.83 ENST00000352433.5
pituitary tumor-transforming 1
chr12_+_104682496 51.89 ENST00000378070.4
thioredoxin reductase 1
chr6_+_24775153 50.91 ENST00000356509.3
ENST00000230056.3
geminin, DNA replication inhibitor
chr4_-_120988229 48.51 ENST00000296509.6
MAD2 mitotic arrest deficient-like 1 (yeast)
chr5_+_159848854 47.17 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
pituitary tumor-transforming 1
chr17_-_4852332 42.93 ENST00000572383.1
profilin 1
chr13_-_31191642 41.86 ENST00000405805.1
high mobility group box 1
chr9_+_75766652 39.35 ENST00000257497.6
annexin A1
chr7_+_141438393 37.08 ENST00000484178.1
ENST00000473783.1
ENST00000481508.1
single-stranded DNA binding protein 1, mitochondrial
chr8_-_101718991 36.36 ENST00000517990.1
poly(A) binding protein, cytoplasmic 1
chr5_+_32531893 35.74 ENST00000512913.1
SUB1 homolog (S. cerevisiae)
chr18_+_657578 35.45 ENST00000323274.10
thymidylate synthetase
chr12_+_53693812 35.40 ENST00000549488.1
chromosome 12 open reading frame 10
chr11_-_47447767 32.87 ENST00000530651.1
ENST00000524447.2
ENST00000531051.2
ENST00000526993.1
ENST00000602866.1
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr8_-_27695552 32.52 ENST00000522944.1
ENST00000301905.4
PDZ binding kinase
chr7_-_87856280 32.43 ENST00000490437.1
ENST00000431660.1
sorcin
chr17_+_73230799 32.34 ENST00000579838.1
nucleoporin 85kDa
chr17_-_73150629 31.96 ENST00000356033.4
ENST00000405458.3
ENST00000409753.3
hematological and neurological expressed 1
chr2_-_176046391 31.78 ENST00000392541.3
ENST00000409194.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr7_-_87856303 31.51 ENST00000394641.3
sorcin
chr17_-_4852243 29.95 ENST00000225655.5
profilin 1
chr20_+_25388293 28.49 ENST00000262460.4
ENST00000429262.2
GINS complex subunit 1 (Psf1 homolog)
chr10_-_126716459 28.28 ENST00000309035.6
C-terminal binding protein 2
chrX_+_21958674 27.47 ENST00000404933.2
spermine synthase
chr2_-_225434538 27.26 ENST00000409096.1
cullin 3
chr2_+_219110149 27.18 ENST00000456575.1
actin related protein 2/3 complex, subunit 2, 34kDa
chr7_+_73868439 27.16 ENST00000424337.2
GTF2I repeat domain containing 1
chr12_-_110883346 27.13 ENST00000547365.1
actin related protein 2/3 complex, subunit 3, 21kDa
chr2_+_198380763 26.78 ENST00000448447.2
ENST00000409360.1
MOB family member 4, phocein
chr2_-_190044480 26.32 ENST00000374866.3
collagen, type V, alpha 2
chr11_-_66206260 26.31 ENST00000329819.4
ENST00000310999.7
ENST00000430466.2
mitochondrial ribosomal protein L11
chr17_+_34848049 26.00 ENST00000588902.1
ENST00000591067.1
zinc finger, HIT-type containing 3
chr14_-_58894223 25.91 ENST00000555593.1
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr14_+_52456327 25.73 ENST00000556760.1
chromosome 14 open reading frame 166
chr22_-_42336209 25.66 ENST00000472374.2
centromere protein M
chrX_+_21958814 25.49 ENST00000379404.1
ENST00000415881.2
spermine synthase
chr7_+_73868220 25.12 ENST00000455841.2
GTF2I repeat domain containing 1
chr20_+_3869423 25.11 ENST00000497424.1
pantothenate kinase 2
chr16_+_84801852 25.01 ENST00000569925.1
ENST00000567526.1
ubiquitin specific peptidase 10
chr16_+_3068393 24.92 ENST00000573001.1
tumor necrosis factor receptor superfamily, member 12A
chr1_+_45205478 24.46 ENST00000452259.1
ENST00000372224.4
kinesin family member 2C
chr9_-_116172946 24.42 ENST00000374171.4
polymerase (DNA directed), epsilon 3, accessory subunit
chr6_-_31704282 24.34 ENST00000375784.3
ENST00000375779.2
chloride intracellular channel 1
chr3_+_138340049 24.33 ENST00000464668.1
Fas apoptotic inhibitory molecule
chr7_+_73868120 23.74 ENST00000265755.3
GTF2I repeat domain containing 1
chr4_-_185655278 23.30 ENST00000281453.5
centromere protein U
chr2_-_69664549 23.16 ENST00000450796.2
ENST00000484177.1
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr8_+_132952112 22.94 ENST00000520362.1
ENST00000519656.1
EFR3 homolog A (S. cerevisiae)
chr5_-_68665469 22.92 ENST00000217893.5
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr3_-_10362725 22.84 ENST00000397109.3
ENST00000428626.1
ENST00000445064.1
ENST00000431352.1
ENST00000397117.1
ENST00000337354.4
ENST00000383801.2
ENST00000432213.1
ENST00000350697.3
SEC13 homolog (S. cerevisiae)
chr2_-_69664586 22.79 ENST00000303698.3
ENST00000394305.1
ENST00000410022.2
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr2_-_3595547 22.70 ENST00000438485.1
Uncharacterized protein
chr17_+_41158742 22.68 ENST00000415816.2
ENST00000438323.2
interferon-induced protein 35
chrX_+_114795489 22.59 ENST00000355899.3
ENST00000537301.1
ENST00000289290.3
plastin 3
chrX_+_69509927 22.56 ENST00000374403.3
kinesin family member 4A
chr1_-_45987526 22.16 ENST00000372079.1
ENST00000262746.1
ENST00000447184.1
ENST00000319248.8
peroxiredoxin 1
chr4_+_169418195 22.14 ENST00000261509.6
ENST00000335742.7
palladin, cytoskeletal associated protein
chr12_+_104337515 22.07 ENST00000550595.1
heat shock protein 90kDa beta (Grp94), member 1
chr1_+_165796753 21.98 ENST00000367879.4
uridine-cytidine kinase 2
chr8_-_124428569 21.97 ENST00000521903.1
ATPase family, AAA domain containing 2
chr18_+_8717369 21.67 ENST00000359865.3
ENST00000400050.3
ENST00000306285.7
SOGA family member 2
chr14_+_52456193 21.32 ENST00000261700.3
chromosome 14 open reading frame 166
chr7_+_112063192 21.23 ENST00000005558.4
interferon-related developmental regulator 1
chr19_+_47634039 21.08 ENST00000597808.1
ENST00000413379.3
ENST00000600706.1
ENST00000540850.1
ENST00000598840.1
ENST00000600753.1
ENST00000270225.7
ENST00000392776.3
SUMO1 activating enzyme subunit 1
chr2_+_192141611 21.07 ENST00000392316.1
myosin IB
chr19_+_14672755 21.01 ENST00000594545.1
trans-2,3-enoyl-CoA reductase
chr9_+_138391805 20.88 ENST00000371785.1
mitochondrial ribosomal protein S2
chr15_+_66797627 20.81 ENST00000565627.1
ENST00000564179.1
zwilch kinetochore protein
chr12_-_109125285 20.72 ENST00000552871.1
ENST00000261401.3
coronin, actin binding protein, 1C
chr5_-_134735568 20.50 ENST00000510038.1
ENST00000304332.4
H2A histone family, member Y
chr14_-_58893832 20.48 ENST00000556007.2
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr2_+_201170596 20.45 ENST00000439084.1
ENST00000409718.1
spermatogenesis associated, serine-rich 2-like
chr7_-_94285472 20.32 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
sarcoglycan, epsilon
chr7_-_94285511 20.26 ENST00000265735.7
sarcoglycan, epsilon
chr8_-_121457608 20.25 ENST00000306185.3
mitochondrial ribosomal protein L13
chr20_+_33759854 20.24 ENST00000216968.4
protein C receptor, endothelial
chr7_+_98923505 20.24 ENST00000432884.2
ENST00000262942.5
actin related protein 2/3 complex, subunit 1A, 41kDa
chr20_-_48732472 20.23 ENST00000340309.3
ENST00000415862.2
ENST00000371677.3
ENST00000420027.2
ubiquitin-conjugating enzyme E2 variant 1
chr3_+_49057876 20.22 ENST00000326912.4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr1_+_169079823 20.20 ENST00000367813.3
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr2_-_62115725 20.16 ENST00000538252.1
ENST00000544079.1
ENST00000394440.3
chaperonin containing TCP1, subunit 4 (delta)
chr1_-_110950255 20.14 ENST00000483260.1
ENST00000474861.2
ENST00000602318.1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
chr17_-_40134339 20.01 ENST00000587727.1
DnaJ (Hsp40) homolog, subfamily C, member 7
chr7_+_12727250 19.85 ENST00000404894.1
ADP-ribosylation factor-like 4A
chr12_+_104680659 19.62 ENST00000526691.1
ENST00000531691.1
ENST00000388854.3
ENST00000354940.6
ENST00000526390.1
ENST00000531689.1
thioredoxin reductase 1
chr1_-_110950564 19.55 ENST00000256644.4
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
chr3_-_149293990 19.52 ENST00000472417.1
WW domain containing transcription regulator 1
chr10_+_70661014 19.42 ENST00000373585.3
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr19_-_47349395 19.40 ENST00000597020.1
adaptor-related protein complex 2, sigma 1 subunit
chr4_+_57845043 19.34 ENST00000433463.1
ENST00000314595.5
polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
chr12_+_49621658 19.31 ENST00000541364.1
tubulin, alpha 1c
chr3_-_131221790 19.31 ENST00000512877.1
ENST00000264995.3
ENST00000511168.1
ENST00000425847.2
mitochondrial ribosomal protein L3
chr20_+_57556263 19.25 ENST00000602795.1
ENST00000344018.3
negative elongation factor complex member C/D
chr20_+_35807512 19.17 ENST00000373622.5
ribophorin II
chr3_+_23847432 19.14 ENST00000346855.3
ubiquitin-conjugating enzyme E2E 1
chr20_+_60878005 19.11 ENST00000253003.2
adhesion regulating molecule 1
chr1_+_161719552 19.07 ENST00000367943.4
dual specificity phosphatase 12
chr7_-_94285402 19.03 ENST00000428696.2
ENST00000445866.2
sarcoglycan, epsilon
chr5_+_154393260 19.01 ENST00000435029.4
kinesin family member 4B
chr2_+_39005325 19.01 ENST00000281950.3
gem (nuclear organelle) associated protein 6
chr8_+_54764346 19.01 ENST00000297313.3
ENST00000344277.6
regulator of G-protein signaling 20
chr5_-_77072085 18.92 ENST00000518338.2
ENST00000520039.1
ENST00000306388.6
ENST00000520361.1
tubulin folding cofactor A
chr15_-_59949667 18.83 ENST00000396061.1
general transcription factor IIA, 2, 12kDa
chr14_-_71107921 18.82 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
chr16_-_23607598 18.78 ENST00000562133.1
ENST00000570319.1
ENST00000007516.3
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa
chr11_-_47447970 18.71 ENST00000298852.3
ENST00000530912.1
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr17_+_73201754 18.61 ENST00000583569.1
ENST00000245544.4
ENST00000579324.1
ENST00000541827.1
ENST00000579298.1
ENST00000447371.2
nucleoporin 85kDa
chr1_+_207943667 18.46 ENST00000462968.2
CD46 molecule, complement regulatory protein
chr3_-_186524234 18.43 ENST00000418288.1
ENST00000296273.2
replication factor C (activator 1) 4, 37kDa
chr8_-_101719159 18.34 ENST00000520868.1
ENST00000522658.1
poly(A) binding protein, cytoplasmic 1
chr4_+_39699664 18.30 ENST00000261427.5
ENST00000510934.1
ENST00000295963.6
ubiquitin-conjugating enzyme E2K
chr12_+_16064258 18.27 ENST00000524480.1
ENST00000531803.1
ENST00000532964.1
deoxyribose-phosphate aldolase (putative)
chr3_-_107777208 18.20 ENST00000398258.3
CD47 molecule
chr15_-_56285742 18.03 ENST00000435532.3
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr5_+_892745 18.01 ENST00000166345.3
thyroid hormone receptor interactor 13
chrX_+_133594168 17.90 ENST00000298556.7
hypoxanthine phosphoribosyltransferase 1
chr7_+_135242652 17.82 ENST00000285968.6
ENST00000440390.2
nucleoporin 205kDa
chr16_+_29690358 17.77 ENST00000395384.4
ENST00000562473.1
quinolinate phosphoribosyltransferase
chr9_-_69262509 17.72 ENST00000377449.1
ENST00000382399.4
ENST00000377439.1
ENST00000377441.1
ENST00000377457.5
COBW domain containing 6
chr5_-_133561752 17.67 ENST00000519718.1
ENST00000481195.1
S-phase kinase-associated protein 1
protein phosphatase 2, catalytic subunit, alpha isozyme
chr12_-_90049828 17.66 ENST00000261173.2
ENST00000348959.3
ATPase, Ca++ transporting, plasma membrane 1
chr1_+_45212074 17.64 ENST00000372217.1
kinesin family member 2C
chr2_-_150444116 17.63 ENST00000428879.1
ENST00000422782.2
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr3_-_149095652 17.59 ENST00000305366.3
transmembrane 4 L six family member 1
chr15_-_66649010 17.58 ENST00000367709.4
ENST00000261881.4
TIMELESS interacting protein
chr11_+_101983176 17.56 ENST00000524575.1
Yes-associated protein 1
chr14_-_23504337 17.53 ENST00000361611.6
proteasome (prosome, macropain) subunit, beta type, 5
chr13_+_28519343 17.51 ENST00000381026.3
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2
chr2_+_198380289 17.50 ENST00000233892.4
ENST00000409916.1
MOB family member 4, phocein
chr18_+_12703002 17.48 ENST00000590217.1
proteasome (prosome, macropain) assembly chaperone 2
chr15_+_44092784 17.45 ENST00000458412.1
huntingtin interacting protein K
chr16_-_8955570 17.41 ENST00000567554.1
calcium regulated heat stable protein 1, 24kDa
chr6_+_10694900 17.25 ENST00000379568.3
PAK1 interacting protein 1
chr17_+_18625336 17.18 ENST00000395671.4
ENST00000571542.1
ENST00000395672.2
ENST00000414850.2
ENST00000424146.2
tripartite motif containing 16-like
chr2_-_220119280 17.15 ENST00000392088.2
tubulin, alpha 4a
chr2_+_58134756 17.09 ENST00000435505.2
ENST00000417641.2
vaccinia related kinase 2
chr18_+_9103957 17.01 ENST00000400033.1
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
chr17_+_18759612 16.99 ENST00000432893.2
ENST00000414602.1
ENST00000574522.1
ENST00000570450.1
ENST00000419071.2
phosphoribosyl pyrophosphate synthetase-associated protein 2
chr12_+_53693466 16.94 ENST00000267103.5
ENST00000548632.1
chromosome 12 open reading frame 10
chr2_+_201936707 16.86 ENST00000433898.1
ENST00000454214.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chrX_-_10851762 16.84 ENST00000380785.1
ENST00000380787.1
midline 1 (Opitz/BBB syndrome)
chr2_-_61765315 16.83 ENST00000406957.1
ENST00000401558.2
exportin 1 (CRM1 homolog, yeast)
chr8_-_87526561 16.78 ENST00000523911.1
regulator of microtubule dynamics 1
chr1_-_95391315 16.78 ENST00000545882.1
ENST00000415017.1
calponin 3, acidic
chr16_-_67970990 16.63 ENST00000358514.4
proteasome (prosome, macropain) subunit, beta type, 10
chr6_-_38670897 16.56 ENST00000373365.4
glyoxalase I
chr19_-_2456922 16.55 ENST00000582871.1
ENST00000325327.3
lamin B2
chr2_+_39005336 16.51 ENST00000409566.1
gem (nuclear organelle) associated protein 6
chr1_-_151965048 16.47 ENST00000368809.1
S100 calcium binding protein A10
chr2_+_73461364 16.47 ENST00000540468.1
ENST00000539919.1
ENST00000258091.5
chaperonin containing TCP1, subunit 7 (eta)
chrX_-_23761317 16.44 ENST00000492081.1
ENST00000379303.5
ENST00000336430.7
acyl-CoA thioesterase 9
chrX_+_23682379 16.39 ENST00000379349.1
peroxiredoxin 4
chr1_-_110283660 16.38 ENST00000361066.2
glutathione S-transferase mu 3 (brain)
chr2_+_73461410 16.37 ENST00000399032.2
ENST00000398422.2
ENST00000537131.1
ENST00000538797.1
chaperonin containing TCP1, subunit 7 (eta)
chr3_+_127317066 16.35 ENST00000265056.7
minichromosome maintenance complex component 2
chr12_+_109535373 16.34 ENST00000242576.2
uracil-DNA glycosylase
chr17_+_52978156 16.30 ENST00000348161.4
target of myb1 (chicken)-like 1
chr3_+_133502877 16.25 ENST00000466490.2
signal recognition particle receptor, B subunit
chr14_+_58711539 16.18 ENST00000216455.4
ENST00000412908.2
ENST00000557508.1
proteasome (prosome, macropain) subunit, alpha type, 3
chr19_-_10697895 16.10 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
adaptor-related protein complex 1, mu 2 subunit
chr1_-_70671216 16.10 ENST00000370952.3
leucine rich repeat containing 40
chr12_-_56121612 16.09 ENST00000546939.1
CD63 molecule
chr4_+_147096837 15.99 ENST00000296581.5
ENST00000502781.1
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr1_+_155278539 15.90 ENST00000447866.1
farnesyl diphosphate synthase
chr1_-_159894319 15.72 ENST00000320307.4
transgelin 2
chr3_-_48647470 15.71 ENST00000203407.5
ubiquinol-cytochrome c reductase core protein I
chr9_-_130966497 15.69 ENST00000393608.1
ENST00000372948.3
CDKN1A interacting zinc finger protein 1
chr8_+_26149007 15.66 ENST00000380737.3
ENST00000524169.1
protein phosphatase 2, regulatory subunit B, alpha
chr12_-_76477707 15.64 ENST00000551992.1
nucleosome assembly protein 1-like 1
chr19_+_23299777 15.59 ENST00000597761.2
zinc finger protein 730
chr10_+_12238171 15.57 ENST00000378900.2
ENST00000442050.1
cell division cycle 123
chr8_+_48920960 15.54 ENST00000523111.2
ENST00000523432.1
ENST00000521346.1
ENST00000517630.1
ubiquitin-conjugating enzyme E2 variant 2
chr10_-_129924468 15.51 ENST00000368653.3
marker of proliferation Ki-67
chr3_+_49058444 15.48 ENST00000326925.6
ENST00000395458.2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr3_+_138340067 15.48 ENST00000479848.1
Fas apoptotic inhibitory molecule
chr8_-_54752406 15.45 ENST00000520188.1
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr5_-_146781153 15.38 ENST00000520473.1
dihydropyrimidinase-like 3
chr4_+_57845024 15.36 ENST00000431623.2
ENST00000441246.2
polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
chr1_+_207262881 15.35 ENST00000451804.2
complement component 4 binding protein, beta
chr4_-_122744998 15.32 ENST00000274026.5
cyclin A2
chr8_+_37887772 15.18 ENST00000338825.4
eukaryotic translation initiation factor 4E binding protein 1
chr17_-_8113542 15.11 ENST00000578549.1
ENST00000535053.1
ENST00000582368.1
aurora kinase B
chr5_+_10250328 15.10 ENST00000515390.1
chaperonin containing TCP1, subunit 5 (epsilon)
chr16_+_30087288 15.01 ENST00000279387.7
ENST00000562664.1
ENST00000562222.1
protein phosphatase 4, catalytic subunit
chr1_+_45212051 15.00 ENST00000372222.3
kinesin family member 2C
chr8_-_80993010 14.96 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
tumor protein D52
chr6_-_8102714 14.94 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
eukaryotic translation elongation factor 1 epsilon 1
chr12_+_4647950 14.93 ENST00000321524.7
ENST00000543041.1
ENST00000228843.9
ENST00000352618.4
ENST00000544927.1
RAD51 associated protein 1
chr3_+_172468472 14.89 ENST00000232458.5
ENST00000392692.3
epithelial cell transforming sequence 2 oncogene
chr1_+_151372010 14.82 ENST00000290541.6
proteasome (prosome, macropain) subunit, beta type, 4
chr6_+_83073952 14.61 ENST00000543496.1
trophoblast glycoprotein
chr4_+_57843876 14.60 ENST00000450656.1
ENST00000381227.1
polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
chr2_-_225362533 14.58 ENST00000451538.1
cullin 3
chr2_+_136343820 14.53 ENST00000410054.1
R3H domain containing 1
chr16_+_28722684 14.49 ENST00000331666.6
ENST00000395587.1
ENST00000569690.1
ENST00000564243.1
eukaryotic translation initiation factor 3, subunit C
chr3_+_133293278 14.44 ENST00000508481.1
ENST00000420115.2
ENST00000504867.1
ENST00000507408.1
ENST00000511392.1
ENST00000515421.1
CDV3 homolog (mouse)
chr4_-_103749179 14.42 ENST00000502690.1
ubiquitin-conjugating enzyme E2D 3
chr12_+_4758264 14.37 ENST00000266544.5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
chr3_-_176914238 14.37 ENST00000430069.1
ENST00000428970.1
transducin (beta)-like 1 X-linked receptor 1
chr14_+_73634537 14.35 ENST00000406768.1
presenilin 1

Network of associatons between targets according to the STRING database.

First level regulatory network of PITX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
17.7 53.0 GO:0006597 spermine biosynthetic process(GO:0006597)
15.2 76.0 GO:0014886 transition between slow and fast fiber(GO:0014886)
13.1 39.3 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
11.3 67.5 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
10.5 41.9 GO:0002424 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
10.5 41.8 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
9.1 63.9 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
9.0 27.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
8.9 35.5 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) transformation of host cell by virus(GO:0019087)
8.2 74.0 GO:0001887 selenium compound metabolic process(GO:0001887)
7.7 76.8 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
7.1 21.2 GO:0007518 myoblast fate determination(GO:0007518)
7.0 62.9 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
6.8 20.5 GO:1903722 regulation of centriole elongation(GO:1903722)
6.8 20.5 GO:1901837 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
6.8 68.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
6.8 27.2 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
6.6 26.3 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
6.5 58.9 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
6.3 81.3 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
6.2 55.4 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
6.0 17.9 GO:0046098 hypoxanthine salvage(GO:0043103) guanine metabolic process(GO:0046098)
5.9 5.9 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
5.8 29.2 GO:1990034 calcium ion export from cell(GO:1990034)
5.5 22.0 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
5.5 22.0 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
5.3 47.7 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
5.3 10.5 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
5.2 47.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
5.1 25.7 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
5.0 20.2 GO:1903288 protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
5.0 15.1 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
4.9 29.6 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
4.9 14.7 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
4.9 63.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
4.8 4.8 GO:1903179 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
4.6 46.2 GO:0051096 positive regulation of helicase activity(GO:0051096)
4.5 18.0 GO:0044111 development involved in symbiotic interaction(GO:0044111)
4.5 13.5 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
4.5 13.5 GO:1900369 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
4.5 13.4 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
4.4 53.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
4.4 13.2 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
4.4 17.5 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
4.3 13.0 GO:2001160 regulation of genetic imprinting(GO:2000653) regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
4.3 21.6 GO:0019348 dolichol metabolic process(GO:0019348)
4.3 12.9 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
4.3 38.7 GO:1903027 regulation of opsonization(GO:1903027)
4.2 12.6 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
4.1 24.6 GO:0010608 posttranscriptional regulation of gene expression(GO:0010608)
4.1 32.7 GO:0032790 ribosome disassembly(GO:0032790)
4.1 12.3 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533) L-kynurenine metabolic process(GO:0097052)
3.9 27.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
3.8 15.3 GO:0071314 cellular response to cocaine(GO:0071314)
3.8 11.4 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
3.8 144.1 GO:2000816 negative regulation of mitotic sister chromatid separation(GO:2000816)
3.7 18.4 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
3.6 10.8 GO:0032079 positive regulation of endodeoxyribonuclease activity(GO:0032079)
3.6 18.0 GO:0007144 female meiosis I(GO:0007144)
3.6 28.5 GO:0010032 meiotic chromosome condensation(GO:0010032)
3.6 17.8 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
3.6 21.3 GO:0090646 mitochondrial tRNA processing(GO:0090646)
3.5 28.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
3.5 14.1 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
3.5 10.5 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
3.5 10.4 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
3.4 10.3 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
3.4 10.1 GO:0007113 endomitotic cell cycle(GO:0007113)
3.3 19.8 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
3.3 16.4 GO:2000255 regulation of male germ cell proliferation(GO:2000254) negative regulation of male germ cell proliferation(GO:2000255)
3.3 16.4 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
3.2 41.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
3.2 31.6 GO:0070141 response to UV-A(GO:0070141)
3.2 28.4 GO:1902416 positive regulation of mRNA binding(GO:1902416)
3.1 9.4 GO:0001807 regulation of type IV hypersensitivity(GO:0001807) positive regulation of female gonad development(GO:2000196)
3.1 30.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
3.0 12.1 GO:0031291 Ran protein signal transduction(GO:0031291)
3.0 6.0 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
3.0 41.5 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
2.9 14.7 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
2.9 11.7 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
2.9 8.8 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
2.9 8.8 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
2.9 8.7 GO:1902463 protein localization to cell leading edge(GO:1902463)
2.9 2.9 GO:1901252 regulation of intracellular transport of viral material(GO:1901252) negative regulation of intracellular transport of viral material(GO:1901253)
2.9 28.7 GO:0008228 opsonization(GO:0008228)
2.8 17.0 GO:0075525 viral translational termination-reinitiation(GO:0075525)
2.8 53.5 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
2.8 11.2 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
2.8 47.4 GO:0035641 locomotory exploration behavior(GO:0035641)
2.8 33.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
2.8 11.1 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
2.7 10.9 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
2.7 5.4 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
2.6 10.6 GO:0007619 courtship behavior(GO:0007619)
2.6 15.9 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
2.6 21.0 GO:0042761 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
2.6 10.4 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
2.6 20.7 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
2.6 97.8 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
2.5 43.3 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
2.5 12.7 GO:0051511 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
2.5 10.2 GO:0048478 replication fork protection(GO:0048478)
2.5 30.3 GO:0035372 protein localization to microtubule(GO:0035372)
2.5 15.1 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
2.5 10.1 GO:0070981 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
2.5 12.5 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
2.5 7.5 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
2.4 7.3 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
2.4 9.7 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
2.4 16.9 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
2.4 7.2 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
2.4 19.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
2.4 14.3 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
2.4 35.6 GO:0043248 proteasome assembly(GO:0043248)
2.4 16.6 GO:0009438 methylglyoxal metabolic process(GO:0009438)
2.3 4.7 GO:0016095 polyprenol catabolic process(GO:0016095)
2.3 7.0 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
2.3 9.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
2.3 9.3 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
2.3 6.9 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
2.3 18.3 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
2.3 13.7 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
2.3 13.6 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
2.3 18.2 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
2.2 21.7 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
2.1 158.4 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
2.1 10.7 GO:0034501 protein localization to kinetochore(GO:0034501)
2.1 99.5 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
2.1 19.0 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
2.1 35.8 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
2.1 20.9 GO:0015939 pantothenate metabolic process(GO:0015939)
2.1 2.1 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
2.1 4.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
2.1 12.4 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
2.0 16.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
2.0 20.2 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
2.0 75.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
2.0 8.0 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633)
2.0 7.9 GO:0046485 ether lipid metabolic process(GO:0046485)
2.0 5.9 GO:0006566 threonine metabolic process(GO:0006566)
2.0 43.2 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
2.0 9.8 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
1.9 87.6 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
1.9 7.8 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
1.9 25.1 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
1.9 5.8 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
1.9 40.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
1.9 5.6 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
1.9 7.5 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
1.9 13.0 GO:0008090 retrograde axonal transport(GO:0008090)
1.8 22.1 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
1.8 7.4 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
1.8 7.3 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
1.8 1.8 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
1.8 5.5 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
1.8 16.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.8 38.0 GO:0051764 actin crosslink formation(GO:0051764)
1.8 1.8 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
1.8 35.8 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
1.8 23.2 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
1.8 5.4 GO:0006624 vacuolar protein processing(GO:0006624)
1.8 33.9 GO:2001046 positive regulation of integrin-mediated signaling pathway(GO:2001046)
1.8 62.4 GO:0006301 postreplication repair(GO:0006301)
1.8 46.1 GO:0050434 positive regulation of viral transcription(GO:0050434)
1.8 8.8 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
1.8 54.6 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
1.7 5.2 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
1.7 5.1 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
1.7 6.8 GO:0009956 radial pattern formation(GO:0009956)
1.7 25.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
1.7 3.4 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
1.7 38.8 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.7 15.2 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836) positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
1.7 11.8 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
1.7 43.6 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
1.7 21.6 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
1.6 141.5 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
1.6 8.2 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
1.6 13.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
1.6 50.7 GO:0032008 positive regulation of TOR signaling(GO:0032008)
1.6 21.2 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
1.6 11.3 GO:0021847 ventricular zone neuroblast division(GO:0021847)
1.6 11.2 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
1.6 14.1 GO:1900121 negative regulation of receptor binding(GO:1900121)
1.6 4.7 GO:1901355 response to rapamycin(GO:1901355)
1.5 10.8 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
1.5 34.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
1.5 21.4 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
1.5 6.1 GO:0061643 chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
1.5 4.5 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
1.5 4.4 GO:0071500 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) cellular response to nitrosative stress(GO:0071500)
1.5 8.8 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
1.5 8.7 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
1.5 4.4 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
1.4 24.3 GO:0016540 protein autoprocessing(GO:0016540)
1.4 20.0 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
1.4 15.7 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
1.4 4.3 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
1.4 4.2 GO:0072711 cellular response to hydroxyurea(GO:0072711)
1.4 18.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
1.4 20.9 GO:0000338 protein deneddylation(GO:0000338)
1.4 4.1 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
1.4 11.0 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
1.4 15.2 GO:0002192 IRES-dependent translational initiation(GO:0002192)
1.4 8.2 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
1.4 6.8 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
1.4 9.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
1.3 10.8 GO:0007498 mesoderm development(GO:0007498)
1.3 26.7 GO:0051983 regulation of chromosome segregation(GO:0051983)
1.3 4.0 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
1.3 32.0 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
1.3 54.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
1.3 3.9 GO:0060613 fat pad development(GO:0060613)
1.3 7.9 GO:1902956 regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956) negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
1.3 11.6 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
1.3 35.4 GO:0090383 phagosome acidification(GO:0090383)
1.3 3.8 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
1.3 11.3 GO:0006552 leucine catabolic process(GO:0006552)
1.3 10.0 GO:0000733 DNA strand renaturation(GO:0000733)
1.2 51.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
1.2 4.9 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
1.2 84.3 GO:0070125 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
1.2 3.7 GO:1904579 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
1.2 2.4 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
1.2 8.4 GO:0089700 protein kinase D signaling(GO:0089700)
1.2 7.2 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
1.2 5.9 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
1.2 13.0 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
1.2 4.7 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
1.2 7.0 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
1.2 9.3 GO:0032364 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) oxygen homeostasis(GO:0032364)
1.2 17.3 GO:0097264 self proteolysis(GO:0097264)
1.2 3.5 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
1.1 2.3 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
1.1 5.7 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
1.1 3.4 GO:0070541 response to platinum ion(GO:0070541)
1.1 10.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
1.1 4.5 GO:0014038 regulation of Schwann cell differentiation(GO:0014038) positive regulation of Schwann cell differentiation(GO:0014040)
1.1 5.6 GO:0070900 positive regulation of mitochondrial translation(GO:0070131) mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
1.1 12.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
1.1 6.7 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
1.1 23.6 GO:0052695 cellular glucuronidation(GO:0052695)
1.1 9.6 GO:0045793 positive regulation of cell size(GO:0045793)
1.1 14.9 GO:2000774 positive regulation of cellular senescence(GO:2000774)
1.1 3.2 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
1.1 3.2 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
1.1 3.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
1.1 14.7 GO:0030050 vesicle transport along actin filament(GO:0030050)
1.0 22.0 GO:0003334 keratinocyte development(GO:0003334)
1.0 3.1 GO:1900063 regulation of peroxisome organization(GO:1900063)
1.0 6.2 GO:0099515 actin filament-based transport(GO:0099515)
1.0 3.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
1.0 33.1 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
1.0 2.0 GO:0016553 base conversion or substitution editing(GO:0016553) cytidine to uridine editing(GO:0016554)
1.0 15.9 GO:0001765 membrane raft assembly(GO:0001765)
1.0 42.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
1.0 4.8 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
1.0 4.8 GO:0035063 nuclear speck organization(GO:0035063)
1.0 18.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.9 10.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.9 10.1 GO:0051601 exocyst localization(GO:0051601)
0.9 6.2 GO:0032445 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.9 8.0 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.9 8.7 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.9 4.3 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.9 3.4 GO:0000103 sulfate assimilation(GO:0000103)
0.9 10.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.9 2.6 GO:1903598 positive regulation of gap junction assembly(GO:1903598)
0.8 3.4 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.8 5.0 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.8 5.6 GO:0051026 chiasma assembly(GO:0051026)
0.8 23.1 GO:0000042 protein targeting to Golgi(GO:0000042)
0.8 2.4 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.8 31.8 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.8 3.8 GO:0015862 uridine transport(GO:0015862)
0.8 3.0 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.8 6.0 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.7 1.5 GO:0044818 mitotic DNA replication checkpoint(GO:0033314) mitotic G2/M transition checkpoint(GO:0044818)
0.7 7.3 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.7 16.0 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.7 2.9 GO:0072205 metanephric collecting duct development(GO:0072205)
0.7 5.0 GO:0036438 maintenance of lens transparency(GO:0036438)
0.7 4.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.7 12.6 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.7 2.8 GO:0019249 lactate biosynthetic process(GO:0019249)
0.7 7.0 GO:0042373 vitamin K metabolic process(GO:0042373)
0.7 2.8 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.7 4.9 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.7 2.8 GO:0097021 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.7 3.4 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.7 3.4 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.7 2.0 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.7 5.4 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.7 4.7 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.7 4.0 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.7 5.3 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.7 4.0 GO:0009441 glycolate metabolic process(GO:0009441)
0.7 5.9 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.7 2.6 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.6 4.4 GO:1902969 mitotic DNA replication(GO:1902969)
0.6 8.7 GO:0043457 regulation of cellular respiration(GO:0043457)
0.6 2.5 GO:0035803 egg coat formation(GO:0035803)
0.6 8.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.6 6.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.6 4.9 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.6 10.7 GO:0051014 actin filament severing(GO:0051014)
0.6 3.0 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.6 4.7 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.6 3.5 GO:0090400 stress-induced premature senescence(GO:0090400)
0.6 1.8 GO:0033341 regulation of collagen binding(GO:0033341)
0.6 9.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.6 2.9 GO:0006574 valine catabolic process(GO:0006574)
0.6 15.8 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.6 0.6 GO:0072282 metanephric nephron tubule morphogenesis(GO:0072282)
0.6 5.6 GO:0042407 cristae formation(GO:0042407)
0.6 6.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.6 20.5 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.5 5.5 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.5 2.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.5 3.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.5 4.3 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.5 4.3 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.5 3.7 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.5 1.0 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.5 6.2 GO:0006825 copper ion transport(GO:0006825)
0.5 21.0 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.5 5.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.5 7.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.5 11.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.5 4.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.5 36.0 GO:0045454 cell redox homeostasis(GO:0045454)
0.5 3.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.5 5.0 GO:0051451 myoblast migration(GO:0051451)
0.5 12.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.5 2.0 GO:0003409 optic cup structural organization(GO:0003409)
0.5 1.5 GO:0061110 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.5 2.9 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.5 33.5 GO:0007062 sister chromatid cohesion(GO:0007062)
0.5 3.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.5 25.5 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.5 6.2 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.5 1.9 GO:0044351 macropinocytosis(GO:0044351)
0.5 1.4 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.5 5.2 GO:0015886 heme transport(GO:0015886)
0.5 1.4 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.5 11.7 GO:0009235 cobalamin metabolic process(GO:0009235)
0.5 4.6 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.5 2.8 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.5 3.7 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.5 1.8 GO:0061046 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.5 1.8 GO:1900193 regulation of oocyte maturation(GO:1900193) negative regulation of oocyte maturation(GO:1900194)
0.5 3.2 GO:0030091 protein repair(GO:0030091)
0.4 6.6 GO:0002227 innate immune response in mucosa(GO:0002227)
0.4 3.5 GO:0051591 response to cAMP(GO:0051591)
0.4 2.6 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.4 3.0 GO:0007097 nuclear migration(GO:0007097)
0.4 4.2 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.4 5.8 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.4 3.7 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.4 2.1 GO:0048839 inner ear development(GO:0048839)
0.4 8.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.4 4.0 GO:0070365 hepatocyte differentiation(GO:0070365)
0.4 2.0 GO:0034334 adherens junction maintenance(GO:0034334)
0.4 2.8 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.4 5.5 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.4 1.2 GO:0033194 response to hydroperoxide(GO:0033194)
0.4 4.7 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.4 8.8 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.4 1.9 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.4 23.0 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.4 1.5 GO:0006783 heme biosynthetic process(GO:0006783)
0.4 6.7 GO:0035855 megakaryocyte development(GO:0035855)
0.4 4.7 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.4 2.1 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.4 16.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.3 8.9 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.3 5.1 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.3 4.1 GO:0019321 pentose metabolic process(GO:0019321)
0.3 4.3 GO:0031648 protein destabilization(GO:0031648)
0.3 2.9 GO:0034198