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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for PITX3

Z-value: 2.06

Motif logo

Transcription factors associated with PITX3

Gene Symbol Gene ID Gene Info
ENSG00000107859.5 paired like homeodomain 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PITX3hg19_v2_chr10_-_104001231_104001274-0.695.7e-32Click!

Activity profile of PITX3 motif

Sorted Z-values of PITX3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_159848807 53.83 ENST00000352433.5
pituitary tumor-transforming 1
chr12_+_104682496 51.89 ENST00000378070.4
thioredoxin reductase 1
chr6_+_24775153 50.91 ENST00000356509.3
ENST00000230056.3
geminin, DNA replication inhibitor
chr4_-_120988229 48.51 ENST00000296509.6
MAD2 mitotic arrest deficient-like 1 (yeast)
chr5_+_159848854 47.17 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
pituitary tumor-transforming 1
chr17_-_4852332 42.93 ENST00000572383.1
profilin 1
chr13_-_31191642 41.86 ENST00000405805.1
high mobility group box 1
chr9_+_75766652 39.35 ENST00000257497.6
annexin A1
chr7_+_141438393 37.08 ENST00000484178.1
ENST00000473783.1
ENST00000481508.1
single-stranded DNA binding protein 1, mitochondrial
chr8_-_101718991 36.36 ENST00000517990.1
poly(A) binding protein, cytoplasmic 1
chr5_+_32531893 35.74 ENST00000512913.1
SUB1 homolog (S. cerevisiae)
chr18_+_657578 35.45 ENST00000323274.10
thymidylate synthetase
chr12_+_53693812 35.40 ENST00000549488.1
chromosome 12 open reading frame 10
chr11_-_47447767 32.87 ENST00000530651.1
ENST00000524447.2
ENST00000531051.2
ENST00000526993.1
ENST00000602866.1
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr8_-_27695552 32.52 ENST00000522944.1
ENST00000301905.4
PDZ binding kinase
chr7_-_87856280 32.43 ENST00000490437.1
ENST00000431660.1
sorcin
chr17_+_73230799 32.34 ENST00000579838.1
nucleoporin 85kDa
chr17_-_73150629 31.96 ENST00000356033.4
ENST00000405458.3
ENST00000409753.3
hematological and neurological expressed 1
chr2_-_176046391 31.78 ENST00000392541.3
ENST00000409194.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr7_-_87856303 31.51 ENST00000394641.3
sorcin
chr17_-_4852243 29.95 ENST00000225655.5
profilin 1
chr20_+_25388293 28.49 ENST00000262460.4
ENST00000429262.2
GINS complex subunit 1 (Psf1 homolog)
chr10_-_126716459 28.28 ENST00000309035.6
C-terminal binding protein 2
chrX_+_21958674 27.47 ENST00000404933.2
spermine synthase
chr2_-_225434538 27.26 ENST00000409096.1
cullin 3
chr2_+_219110149 27.18 ENST00000456575.1
actin related protein 2/3 complex, subunit 2, 34kDa
chr7_+_73868439 27.16 ENST00000424337.2
GTF2I repeat domain containing 1
chr12_-_110883346 27.13 ENST00000547365.1
actin related protein 2/3 complex, subunit 3, 21kDa
chr2_+_198380763 26.78 ENST00000448447.2
ENST00000409360.1
MOB family member 4, phocein
chr2_-_190044480 26.32 ENST00000374866.3
collagen, type V, alpha 2
chr11_-_66206260 26.31 ENST00000329819.4
ENST00000310999.7
ENST00000430466.2
mitochondrial ribosomal protein L11
chr17_+_34848049 26.00 ENST00000588902.1
ENST00000591067.1
zinc finger, HIT-type containing 3
chr14_-_58894223 25.91 ENST00000555593.1
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr14_+_52456327 25.73 ENST00000556760.1
chromosome 14 open reading frame 166
chr22_-_42336209 25.66 ENST00000472374.2
centromere protein M
chrX_+_21958814 25.49 ENST00000379404.1
ENST00000415881.2
spermine synthase
chr7_+_73868220 25.12 ENST00000455841.2
GTF2I repeat domain containing 1
chr20_+_3869423 25.11 ENST00000497424.1
pantothenate kinase 2
chr16_+_84801852 25.01 ENST00000569925.1
ENST00000567526.1
ubiquitin specific peptidase 10
chr16_+_3068393 24.92 ENST00000573001.1
tumor necrosis factor receptor superfamily, member 12A
chr1_+_45205478 24.46 ENST00000452259.1
ENST00000372224.4
kinesin family member 2C
chr9_-_116172946 24.42 ENST00000374171.4
polymerase (DNA directed), epsilon 3, accessory subunit
chr6_-_31704282 24.34 ENST00000375784.3
ENST00000375779.2
chloride intracellular channel 1
chr3_+_138340049 24.33 ENST00000464668.1
Fas apoptotic inhibitory molecule
chr7_+_73868120 23.74 ENST00000265755.3
GTF2I repeat domain containing 1
chr4_-_185655278 23.30 ENST00000281453.5
centromere protein U
chr2_-_69664549 23.16 ENST00000450796.2
ENST00000484177.1
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr8_+_132952112 22.94 ENST00000520362.1
ENST00000519656.1
EFR3 homolog A (S. cerevisiae)
chr5_-_68665469 22.92 ENST00000217893.5
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr3_-_10362725 22.84 ENST00000397109.3
ENST00000428626.1
ENST00000445064.1
ENST00000431352.1
ENST00000397117.1
ENST00000337354.4
ENST00000383801.2
ENST00000432213.1
ENST00000350697.3
SEC13 homolog (S. cerevisiae)
chr2_-_69664586 22.79 ENST00000303698.3
ENST00000394305.1
ENST00000410022.2
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr2_-_3595547 22.70 ENST00000438485.1
Uncharacterized protein
chr17_+_41158742 22.68 ENST00000415816.2
ENST00000438323.2
interferon-induced protein 35
chrX_+_114795489 22.59 ENST00000355899.3
ENST00000537301.1
ENST00000289290.3
plastin 3
chrX_+_69509927 22.56 ENST00000374403.3
kinesin family member 4A
chr1_-_45987526 22.16 ENST00000372079.1
ENST00000262746.1
ENST00000447184.1
ENST00000319248.8
peroxiredoxin 1
chr4_+_169418195 22.14 ENST00000261509.6
ENST00000335742.7
palladin, cytoskeletal associated protein
chr12_+_104337515 22.07 ENST00000550595.1
heat shock protein 90kDa beta (Grp94), member 1
chr1_+_165796753 21.98 ENST00000367879.4
uridine-cytidine kinase 2
chr8_-_124428569 21.97 ENST00000521903.1
ATPase family, AAA domain containing 2
chr18_+_8717369 21.67 ENST00000359865.3
ENST00000400050.3
ENST00000306285.7
SOGA family member 2
chr14_+_52456193 21.32 ENST00000261700.3
chromosome 14 open reading frame 166
chr7_+_112063192 21.23 ENST00000005558.4
interferon-related developmental regulator 1
chr19_+_47634039 21.08 ENST00000597808.1
ENST00000413379.3
ENST00000600706.1
ENST00000540850.1
ENST00000598840.1
ENST00000600753.1
ENST00000270225.7
ENST00000392776.3
SUMO1 activating enzyme subunit 1
chr2_+_192141611 21.07 ENST00000392316.1
myosin IB
chr19_+_14672755 21.01 ENST00000594545.1
trans-2,3-enoyl-CoA reductase
chr9_+_138391805 20.88 ENST00000371785.1
mitochondrial ribosomal protein S2
chr15_+_66797627 20.81 ENST00000565627.1
ENST00000564179.1
zwilch kinetochore protein
chr12_-_109125285 20.72 ENST00000552871.1
ENST00000261401.3
coronin, actin binding protein, 1C
chr5_-_134735568 20.50 ENST00000510038.1
ENST00000304332.4
H2A histone family, member Y
chr14_-_58893832 20.48 ENST00000556007.2
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr2_+_201170596 20.45 ENST00000439084.1
ENST00000409718.1
spermatogenesis associated, serine-rich 2-like
chr7_-_94285472 20.32 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
sarcoglycan, epsilon
chr7_-_94285511 20.26 ENST00000265735.7
sarcoglycan, epsilon
chr8_-_121457608 20.25 ENST00000306185.3
mitochondrial ribosomal protein L13
chr20_+_33759854 20.24 ENST00000216968.4
protein C receptor, endothelial
chr7_+_98923505 20.24 ENST00000432884.2
ENST00000262942.5
actin related protein 2/3 complex, subunit 1A, 41kDa
chr20_-_48732472 20.23 ENST00000340309.3
ENST00000415862.2
ENST00000371677.3
ENST00000420027.2
ubiquitin-conjugating enzyme E2 variant 1
chr3_+_49057876 20.22 ENST00000326912.4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr1_+_169079823 20.20 ENST00000367813.3
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr2_-_62115725 20.16 ENST00000538252.1
ENST00000544079.1
ENST00000394440.3
chaperonin containing TCP1, subunit 4 (delta)
chr1_-_110950255 20.14 ENST00000483260.1
ENST00000474861.2
ENST00000602318.1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
chr17_-_40134339 20.01 ENST00000587727.1
DnaJ (Hsp40) homolog, subfamily C, member 7
chr7_+_12727250 19.85 ENST00000404894.1
ADP-ribosylation factor-like 4A
chr12_+_104680659 19.62 ENST00000526691.1
ENST00000531691.1
ENST00000388854.3
ENST00000354940.6
ENST00000526390.1
ENST00000531689.1
thioredoxin reductase 1
chr1_-_110950564 19.55 ENST00000256644.4
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
chr3_-_149293990 19.52 ENST00000472417.1
WW domain containing transcription regulator 1
chr10_+_70661014 19.42 ENST00000373585.3
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr19_-_47349395 19.40 ENST00000597020.1
adaptor-related protein complex 2, sigma 1 subunit
chr4_+_57845043 19.34 ENST00000433463.1
ENST00000314595.5
polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
chr12_+_49621658 19.31 ENST00000541364.1
tubulin, alpha 1c
chr3_-_131221790 19.31 ENST00000512877.1
ENST00000264995.3
ENST00000511168.1
ENST00000425847.2
mitochondrial ribosomal protein L3
chr20_+_57556263 19.25 ENST00000602795.1
ENST00000344018.3
negative elongation factor complex member C/D
chr20_+_35807512 19.17 ENST00000373622.5
ribophorin II
chr3_+_23847432 19.14 ENST00000346855.3
ubiquitin-conjugating enzyme E2E 1
chr20_+_60878005 19.11 ENST00000253003.2
adhesion regulating molecule 1
chr1_+_161719552 19.07 ENST00000367943.4
dual specificity phosphatase 12
chr7_-_94285402 19.03 ENST00000428696.2
ENST00000445866.2
sarcoglycan, epsilon
chr5_+_154393260 19.01 ENST00000435029.4
kinesin family member 4B
chr2_+_39005325 19.01 ENST00000281950.3
gem (nuclear organelle) associated protein 6
chr8_+_54764346 19.01 ENST00000297313.3
ENST00000344277.6
regulator of G-protein signaling 20
chr5_-_77072085 18.92 ENST00000518338.2
ENST00000520039.1
ENST00000306388.6
ENST00000520361.1
tubulin folding cofactor A
chr15_-_59949667 18.83 ENST00000396061.1
general transcription factor IIA, 2, 12kDa
chr14_-_71107921 18.82 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
chr16_-_23607598 18.78 ENST00000562133.1
ENST00000570319.1
ENST00000007516.3
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa
chr11_-_47447970 18.71 ENST00000298852.3
ENST00000530912.1
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr17_+_73201754 18.61 ENST00000583569.1
ENST00000245544.4
ENST00000579324.1
ENST00000541827.1
ENST00000579298.1
ENST00000447371.2
nucleoporin 85kDa
chr1_+_207943667 18.46 ENST00000462968.2
CD46 molecule, complement regulatory protein
chr3_-_186524234 18.43 ENST00000418288.1
ENST00000296273.2
replication factor C (activator 1) 4, 37kDa
chr8_-_101719159 18.34 ENST00000520868.1
ENST00000522658.1
poly(A) binding protein, cytoplasmic 1
chr4_+_39699664 18.30 ENST00000261427.5
ENST00000510934.1
ENST00000295963.6
ubiquitin-conjugating enzyme E2K
chr12_+_16064258 18.27 ENST00000524480.1
ENST00000531803.1
ENST00000532964.1
deoxyribose-phosphate aldolase (putative)
chr3_-_107777208 18.20 ENST00000398258.3
CD47 molecule
chr15_-_56285742 18.03 ENST00000435532.3
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr5_+_892745 18.01 ENST00000166345.3
thyroid hormone receptor interactor 13
chrX_+_133594168 17.90 ENST00000298556.7
hypoxanthine phosphoribosyltransferase 1
chr7_+_135242652 17.82 ENST00000285968.6
ENST00000440390.2
nucleoporin 205kDa
chr16_+_29690358 17.77 ENST00000395384.4
ENST00000562473.1
quinolinate phosphoribosyltransferase
chr9_-_69262509 17.72 ENST00000377449.1
ENST00000382399.4
ENST00000377439.1
ENST00000377441.1
ENST00000377457.5
COBW domain containing 6
chr5_-_133561752 17.67 ENST00000519718.1
ENST00000481195.1
S-phase kinase-associated protein 1
protein phosphatase 2, catalytic subunit, alpha isozyme
chr12_-_90049828 17.66 ENST00000261173.2
ENST00000348959.3
ATPase, Ca++ transporting, plasma membrane 1
chr1_+_45212074 17.64 ENST00000372217.1
kinesin family member 2C
chr2_-_150444116 17.63 ENST00000428879.1
ENST00000422782.2
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr3_-_149095652 17.59 ENST00000305366.3
transmembrane 4 L six family member 1
chr15_-_66649010 17.58 ENST00000367709.4
ENST00000261881.4
TIMELESS interacting protein
chr11_+_101983176 17.56 ENST00000524575.1
Yes-associated protein 1
chr14_-_23504337 17.53 ENST00000361611.6
proteasome (prosome, macropain) subunit, beta type, 5
chr13_+_28519343 17.51 ENST00000381026.3
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2
chr2_+_198380289 17.50 ENST00000233892.4
ENST00000409916.1
MOB family member 4, phocein
chr18_+_12703002 17.48 ENST00000590217.1
proteasome (prosome, macropain) assembly chaperone 2
chr15_+_44092784 17.45 ENST00000458412.1
huntingtin interacting protein K
chr16_-_8955570 17.41 ENST00000567554.1
calcium regulated heat stable protein 1, 24kDa
chr6_+_10694900 17.25 ENST00000379568.3
PAK1 interacting protein 1
chr17_+_18625336 17.18 ENST00000395671.4
ENST00000571542.1
ENST00000395672.2
ENST00000414850.2
ENST00000424146.2
tripartite motif containing 16-like
chr2_-_220119280 17.15 ENST00000392088.2
tubulin, alpha 4a
chr2_+_58134756 17.09 ENST00000435505.2
ENST00000417641.2
vaccinia related kinase 2
chr18_+_9103957 17.01 ENST00000400033.1
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
chr17_+_18759612 16.99 ENST00000432893.2
ENST00000414602.1
ENST00000574522.1
ENST00000570450.1
ENST00000419071.2
phosphoribosyl pyrophosphate synthetase-associated protein 2
chr12_+_53693466 16.94 ENST00000267103.5
ENST00000548632.1
chromosome 12 open reading frame 10
chr2_+_201936707 16.86 ENST00000433898.1
ENST00000454214.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chrX_-_10851762 16.84 ENST00000380785.1
ENST00000380787.1
midline 1 (Opitz/BBB syndrome)
chr2_-_61765315 16.83 ENST00000406957.1
ENST00000401558.2
exportin 1 (CRM1 homolog, yeast)
chr8_-_87526561 16.78 ENST00000523911.1
regulator of microtubule dynamics 1
chr1_-_95391315 16.78 ENST00000545882.1
ENST00000415017.1
calponin 3, acidic
chr16_-_67970990 16.63 ENST00000358514.4
proteasome (prosome, macropain) subunit, beta type, 10
chr6_-_38670897 16.56 ENST00000373365.4
glyoxalase I
chr19_-_2456922 16.55 ENST00000582871.1
ENST00000325327.3
lamin B2
chr2_+_39005336 16.51 ENST00000409566.1
gem (nuclear organelle) associated protein 6
chr1_-_151965048 16.47 ENST00000368809.1
S100 calcium binding protein A10
chr2_+_73461364 16.47 ENST00000540468.1
ENST00000539919.1
ENST00000258091.5
chaperonin containing TCP1, subunit 7 (eta)
chrX_-_23761317 16.44 ENST00000492081.1
ENST00000379303.5
ENST00000336430.7
acyl-CoA thioesterase 9
chrX_+_23682379 16.39 ENST00000379349.1
peroxiredoxin 4
chr1_-_110283660 16.38 ENST00000361066.2
glutathione S-transferase mu 3 (brain)
chr2_+_73461410 16.37 ENST00000399032.2
ENST00000398422.2
ENST00000537131.1
ENST00000538797.1
chaperonin containing TCP1, subunit 7 (eta)
chr3_+_127317066 16.35 ENST00000265056.7
minichromosome maintenance complex component 2
chr12_+_109535373 16.34 ENST00000242576.2
uracil-DNA glycosylase
chr17_+_52978156 16.30 ENST00000348161.4
target of myb1 (chicken)-like 1
chr3_+_133502877 16.25 ENST00000466490.2
signal recognition particle receptor, B subunit
chr14_+_58711539 16.18 ENST00000216455.4
ENST00000412908.2
ENST00000557508.1
proteasome (prosome, macropain) subunit, alpha type, 3
chr19_-_10697895 16.10 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
adaptor-related protein complex 1, mu 2 subunit
chr1_-_70671216 16.10 ENST00000370952.3
leucine rich repeat containing 40
chr12_-_56121612 16.09 ENST00000546939.1
CD63 molecule
chr4_+_147096837 15.99 ENST00000296581.5
ENST00000502781.1
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr1_+_155278539 15.90 ENST00000447866.1
farnesyl diphosphate synthase
chr1_-_159894319 15.72 ENST00000320307.4
transgelin 2
chr3_-_48647470 15.71 ENST00000203407.5
ubiquinol-cytochrome c reductase core protein I
chr9_-_130966497 15.69 ENST00000393608.1
ENST00000372948.3
CDKN1A interacting zinc finger protein 1
chr8_+_26149007 15.66 ENST00000380737.3
ENST00000524169.1
protein phosphatase 2, regulatory subunit B, alpha
chr12_-_76477707 15.64 ENST00000551992.1
nucleosome assembly protein 1-like 1
chr19_+_23299777 15.59 ENST00000597761.2
zinc finger protein 730
chr10_+_12238171 15.57 ENST00000378900.2
ENST00000442050.1
cell division cycle 123
chr8_+_48920960 15.54 ENST00000523111.2
ENST00000523432.1
ENST00000521346.1
ENST00000517630.1
ubiquitin-conjugating enzyme E2 variant 2
chr10_-_129924468 15.51 ENST00000368653.3
marker of proliferation Ki-67
chr3_+_49058444 15.48 ENST00000326925.6
ENST00000395458.2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr3_+_138340067 15.48 ENST00000479848.1
Fas apoptotic inhibitory molecule
chr8_-_54752406 15.45 ENST00000520188.1
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr5_-_146781153 15.38 ENST00000520473.1
dihydropyrimidinase-like 3
chr4_+_57845024 15.36 ENST00000431623.2
ENST00000441246.2
polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
chr1_+_207262881 15.35 ENST00000451804.2
complement component 4 binding protein, beta
chr4_-_122744998 15.32 ENST00000274026.5
cyclin A2
chr8_+_37887772 15.18 ENST00000338825.4
eukaryotic translation initiation factor 4E binding protein 1
chr17_-_8113542 15.11 ENST00000578549.1
ENST00000535053.1
ENST00000582368.1
aurora kinase B
chr5_+_10250328 15.10 ENST00000515390.1
chaperonin containing TCP1, subunit 5 (epsilon)
chr16_+_30087288 15.01 ENST00000279387.7
ENST00000562664.1
ENST00000562222.1
protein phosphatase 4, catalytic subunit
chr1_+_45212051 15.00 ENST00000372222.3
kinesin family member 2C
chr8_-_80993010 14.96 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
tumor protein D52
chr6_-_8102714 14.94 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
eukaryotic translation elongation factor 1 epsilon 1
chr12_+_4647950 14.93 ENST00000321524.7
ENST00000543041.1
ENST00000228843.9
ENST00000352618.4
ENST00000544927.1
RAD51 associated protein 1
chr3_+_172468472 14.89 ENST00000232458.5
ENST00000392692.3
epithelial cell transforming sequence 2 oncogene
chr1_+_151372010 14.82 ENST00000290541.6
proteasome (prosome, macropain) subunit, beta type, 4
chr6_+_83073952 14.61 ENST00000543496.1
trophoblast glycoprotein
chr4_+_57843876 14.60 ENST00000450656.1
ENST00000381227.1
polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
chr2_-_225362533 14.58 ENST00000451538.1
cullin 3
chr2_+_136343820 14.53 ENST00000410054.1
R3H domain containing 1
chr16_+_28722684 14.49 ENST00000331666.6
ENST00000395587.1
ENST00000569690.1
ENST00000564243.1
eukaryotic translation initiation factor 3, subunit C
chr3_+_133293278 14.44 ENST00000508481.1
ENST00000420115.2
ENST00000504867.1
ENST00000507408.1
ENST00000511392.1
ENST00000515421.1
CDV3 homolog (mouse)
chr4_-_103749179 14.42 ENST00000502690.1
ubiquitin-conjugating enzyme E2D 3
chr12_+_4758264 14.37 ENST00000266544.5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
chr3_-_176914238 14.37 ENST00000430069.1
ENST00000428970.1
transducin (beta)-like 1 X-linked receptor 1
chr14_+_73634537 14.35 ENST00000406768.1
presenilin 1

Network of associatons between targets according to the STRING database.

First level regulatory network of PITX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
17.7 53.0 GO:0006597 spermine biosynthetic process(GO:0006597)
15.2 76.0 GO:0014886 transition between slow and fast fiber(GO:0014886)
13.1 39.3 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
11.3 67.5 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
10.5 41.9 GO:0002424 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
10.5 41.8 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
9.1 63.9 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
9.0 27.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
8.9 35.5 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) transformation of host cell by virus(GO:0019087)
8.2 74.0 GO:0001887 selenium compound metabolic process(GO:0001887)
7.7 76.8 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
7.1 21.2 GO:0007518 myoblast fate determination(GO:0007518)
7.0 62.9 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
6.8 20.5 GO:1903722 regulation of centriole elongation(GO:1903722)
6.8 20.5 GO:1901837 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
6.8 68.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
6.8 27.2 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
6.6 26.3 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
6.5 58.9 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
6.3 81.3 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
6.2 55.4 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
6.0 17.9 GO:0046098 hypoxanthine salvage(GO:0043103) guanine metabolic process(GO:0046098)
5.9 5.9 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
5.8 29.2 GO:1990034 calcium ion export from cell(GO:1990034)
5.5 22.0 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
5.5 22.0 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
5.3 47.7 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
5.3 10.5 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
5.2 47.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
5.1 25.7 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
5.0 20.2 GO:1903288 protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
5.0 15.1 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
4.9 29.6 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
4.9 14.7 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
4.9 63.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
4.8 4.8 GO:1903179 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
4.6 46.2 GO:0051096 positive regulation of helicase activity(GO:0051096)
4.5 18.0 GO:0044111 development involved in symbiotic interaction(GO:0044111)
4.5 13.5 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
4.5 13.5 GO:1900369 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
4.5 13.4 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
4.4 53.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
4.4 13.2 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
4.4 17.5 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
4.3 13.0 GO:2001160 regulation of genetic imprinting(GO:2000653) regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
4.3 21.6 GO:0019348 dolichol metabolic process(GO:0019348)
4.3 12.9 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
4.3 38.7 GO:1903027 regulation of opsonization(GO:1903027)
4.2 12.6 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
4.1 24.6 GO:0010608 posttranscriptional regulation of gene expression(GO:0010608)
4.1 32.7 GO:0032790 ribosome disassembly(GO:0032790)
4.1 12.3 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533) L-kynurenine metabolic process(GO:0097052)
3.9 27.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
3.8 15.3 GO:0071314 cellular response to cocaine(GO:0071314)
3.8 11.4 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
3.8 144.1 GO:2000816 negative regulation of mitotic sister chromatid separation(GO:2000816)
3.7 18.4 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
3.6 10.8 GO:0032079 positive regulation of endodeoxyribonuclease activity(GO:0032079)
3.6 18.0 GO:0007144 female meiosis I(GO:0007144)
3.6 28.5 GO:0010032 meiotic chromosome condensation(GO:0010032)
3.6 17.8 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
3.6 21.3 GO:0090646 mitochondrial tRNA processing(GO:0090646)
3.5 28.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
3.5 14.1 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
3.5 10.5 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
3.5 10.4 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
3.4 10.3 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
3.4 10.1 GO:0007113 endomitotic cell cycle(GO:0007113)
3.3 19.8 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
3.3 16.4 GO:2000255 regulation of male germ cell proliferation(GO:2000254) negative regulation of male germ cell proliferation(GO:2000255)
3.3 16.4 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
3.2 41.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
3.2 31.6 GO:0070141 response to UV-A(GO:0070141)
3.2 28.4 GO:1902416 positive regulation of mRNA binding(GO:1902416)
3.1 9.4 GO:0001807 regulation of type IV hypersensitivity(GO:0001807) positive regulation of female gonad development(GO:2000196)
3.1 30.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
3.0 12.1 GO:0031291 Ran protein signal transduction(GO:0031291)
3.0 6.0 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
3.0 41.5 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
2.9 14.7 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
2.9 11.7 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
2.9 8.8 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
2.9 8.8 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
2.9 8.7 GO:1902463 protein localization to cell leading edge(GO:1902463)
2.9 2.9 GO:1901252 regulation of intracellular transport of viral material(GO:1901252) negative regulation of intracellular transport of viral material(GO:1901253)
2.9 28.7 GO:0008228 opsonization(GO:0008228)
2.8 17.0 GO:0075525 viral translational termination-reinitiation(GO:0075525)
2.8 53.5 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
2.8 11.2 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
2.8 47.4 GO:0035641 locomotory exploration behavior(GO:0035641)
2.8 33.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
2.8 11.1 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
2.7 10.9 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
2.7 5.4 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
2.6 10.6 GO:0007619 courtship behavior(GO:0007619)
2.6 15.9 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
2.6 21.0 GO:0042761 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
2.6 10.4 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
2.6 20.7 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
2.6 97.8 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
2.5 43.3 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
2.5 12.7 GO:0051511 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
2.5 10.2 GO:0048478 replication fork protection(GO:0048478)
2.5 30.3 GO:0035372 protein localization to microtubule(GO:0035372)
2.5 15.1 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
2.5 10.1 GO:0070981 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
2.5 12.5 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
2.5 7.5 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
2.4 7.3 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
2.4 9.7 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
2.4 16.9 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
2.4 7.2 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
2.4 19.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
2.4 14.3 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
2.4 35.6 GO:0043248 proteasome assembly(GO:0043248)
2.4 16.6 GO:0009438 methylglyoxal metabolic process(GO:0009438)
2.3 4.7 GO:0016095 polyprenol catabolic process(GO:0016095)
2.3 7.0 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
2.3 9.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
2.3 9.3 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
2.3 6.9 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
2.3 18.3 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
2.3 13.7 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
2.3 13.6 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
2.3 18.2 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
2.2 21.7 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
2.1 158.4 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
2.1 10.7 GO:0034501 protein localization to kinetochore(GO:0034501)
2.1 99.5 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
2.1 19.0 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
2.1 35.8 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
2.1 20.9 GO:0015939 pantothenate metabolic process(GO:0015939)
2.1 2.1 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
2.1 4.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
2.1 12.4 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
2.0 16.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
2.0 20.2 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
2.0 75.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
2.0 8.0 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633)
2.0 7.9 GO:0046485 ether lipid metabolic process(GO:0046485)
2.0 5.9 GO:0006566 threonine metabolic process(GO:0006566)
2.0 43.2 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
2.0 9.8 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
1.9 87.6 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
1.9 7.8 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
1.9 25.1 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
1.9 5.8 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
1.9 40.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
1.9 5.6 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
1.9 7.5 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
1.9 13.0 GO:0008090 retrograde axonal transport(GO:0008090)
1.8 22.1 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
1.8 7.4 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
1.8 7.3 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
1.8 1.8 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
1.8 5.5 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
1.8 16.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.8 38.0 GO:0051764 actin crosslink formation(GO:0051764)
1.8 1.8 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
1.8 35.8 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
1.8 23.2 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
1.8 5.4 GO:0006624 vacuolar protein processing(GO:0006624)
1.8 33.9 GO:2001046 positive regulation of integrin-mediated signaling pathway(GO:2001046)
1.8 62.4 GO:0006301 postreplication repair(GO:0006301)
1.8 46.1 GO:0050434 positive regulation of viral transcription(GO:0050434)
1.8 8.8 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
1.8 54.6 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
1.7 5.2 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
1.7 5.1 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
1.7 6.8 GO:0009956 radial pattern formation(GO:0009956)
1.7 25.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
1.7 3.4 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
1.7 38.8 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.7 15.2 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836) positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
1.7 11.8 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
1.7 43.6 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
1.7 21.6 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
1.6 141.5 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
1.6 8.2 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
1.6 13.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
1.6 50.7 GO:0032008 positive regulation of TOR signaling(GO:0032008)
1.6 21.2 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
1.6 11.3 GO:0021847 ventricular zone neuroblast division(GO:0021847)
1.6 11.2 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
1.6 14.1 GO:1900121 negative regulation of receptor binding(GO:1900121)
1.6 4.7 GO:1901355 response to rapamycin(GO:1901355)
1.5 10.8 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
1.5 34.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
1.5 21.4 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
1.5 6.1 GO:0061643 chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
1.5 4.5 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
1.5 4.4 GO:0071500 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) cellular response to nitrosative stress(GO:0071500)
1.5 8.8 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
1.5 8.7 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
1.5 4.4 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
1.4 24.3 GO:0016540 protein autoprocessing(GO:0016540)
1.4 20.0 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
1.4 15.7 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
1.4 4.3 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
1.4 4.2 GO:0072711 cellular response to hydroxyurea(GO:0072711)
1.4 18.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
1.4 20.9 GO:0000338 protein deneddylation(GO:0000338)
1.4 4.1 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
1.4 11.0 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
1.4 15.2 GO:0002192 IRES-dependent translational initiation(GO:0002192)
1.4 8.2 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
1.4 6.8 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
1.4 9.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
1.3 10.8 GO:0007498 mesoderm development(GO:0007498)
1.3 26.7 GO:0051983 regulation of chromosome segregation(GO:0051983)
1.3 4.0 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
1.3 32.0 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
1.3 54.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
1.3 3.9 GO:0060613 fat pad development(GO:0060613)
1.3 7.9 GO:1902956 regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956) negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
1.3 11.6 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
1.3 35.4 GO:0090383 phagosome acidification(GO:0090383)
1.3 3.8 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
1.3 11.3 GO:0006552 leucine catabolic process(GO:0006552)
1.3 10.0 GO:0000733 DNA strand renaturation(GO:0000733)
1.2 51.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
1.2 4.9 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
1.2 84.3 GO:0070125 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
1.2 3.7 GO:1904579 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
1.2 2.4 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
1.2 8.4 GO:0089700 protein kinase D signaling(GO:0089700)
1.2 7.2 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
1.2 5.9 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
1.2 13.0 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
1.2 4.7 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
1.2 7.0 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
1.2 9.3 GO:0032364 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) oxygen homeostasis(GO:0032364)
1.2 17.3 GO:0097264 self proteolysis(GO:0097264)
1.2 3.5 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
1.1 2.3 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
1.1 5.7 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
1.1 3.4 GO:0070541 response to platinum ion(GO:0070541)
1.1 10.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
1.1 4.5 GO:0014038 regulation of Schwann cell differentiation(GO:0014038) positive regulation of Schwann cell differentiation(GO:0014040)
1.1 5.6 GO:0070900 positive regulation of mitochondrial translation(GO:0070131) mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
1.1 12.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
1.1 6.7 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
1.1 23.6 GO:0052695 cellular glucuronidation(GO:0052695)
1.1 9.6 GO:0045793 positive regulation of cell size(GO:0045793)
1.1 14.9 GO:2000774 positive regulation of cellular senescence(GO:2000774)
1.1 3.2 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
1.1 3.2 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
1.1 3.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
1.1 14.7 GO:0030050 vesicle transport along actin filament(GO:0030050)
1.0 22.0 GO:0003334 keratinocyte development(GO:0003334)
1.0 3.1 GO:1900063 regulation of peroxisome organization(GO:1900063)
1.0 6.2 GO:0099515 actin filament-based transport(GO:0099515)
1.0 3.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
1.0 33.1 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
1.0 2.0 GO:0016553 base conversion or substitution editing(GO:0016553) cytidine to uridine editing(GO:0016554)
1.0 15.9 GO:0001765 membrane raft assembly(GO:0001765)
1.0 42.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
1.0 4.8 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
1.0 4.8 GO:0035063 nuclear speck organization(GO:0035063)
1.0 18.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.9 10.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.9 10.1 GO:0051601 exocyst localization(GO:0051601)
0.9 6.2 GO:0032445 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.9 8.0 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.9 8.7 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.9 4.3 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.9 3.4 GO:0000103 sulfate assimilation(GO:0000103)
0.9 10.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.9 2.6 GO:1903598 positive regulation of gap junction assembly(GO:1903598)
0.8 3.4 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.8 5.0 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.8 5.6 GO:0051026 chiasma assembly(GO:0051026)
0.8 23.1 GO:0000042 protein targeting to Golgi(GO:0000042)
0.8 2.4 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.8 31.8 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.8 3.8 GO:0015862 uridine transport(GO:0015862)
0.8 3.0 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.8 6.0 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.7 1.5 GO:0044818 mitotic DNA replication checkpoint(GO:0033314) mitotic G2/M transition checkpoint(GO:0044818)
0.7 7.3 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.7 16.0 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.7 2.9 GO:0072205 metanephric collecting duct development(GO:0072205)
0.7 5.0 GO:0036438 maintenance of lens transparency(GO:0036438)
0.7 4.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.7 12.6 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.7 2.8 GO:0019249 lactate biosynthetic process(GO:0019249)
0.7 7.0 GO:0042373 vitamin K metabolic process(GO:0042373)
0.7 2.8 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.7 4.9 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.7 2.8 GO:0097021 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.7 3.4 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.7 3.4 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.7 2.0 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.7 5.4 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.7 4.7 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.7 4.0 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.7 5.3 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.7 4.0 GO:0009441 glycolate metabolic process(GO:0009441)
0.7 5.9 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.7 2.6 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.6 4.4 GO:1902969 mitotic DNA replication(GO:1902969)
0.6 8.7 GO:0043457 regulation of cellular respiration(GO:0043457)
0.6 2.5 GO:0035803 egg coat formation(GO:0035803)
0.6 8.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.6 6.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.6 4.9 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.6 10.7 GO:0051014 actin filament severing(GO:0051014)
0.6 3.0 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.6 4.7 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.6 3.5 GO:0090400 stress-induced premature senescence(GO:0090400)
0.6 1.8 GO:0033341 regulation of collagen binding(GO:0033341)
0.6 9.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.6 2.9 GO:0006574 valine catabolic process(GO:0006574)
0.6 15.8 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.6 0.6 GO:0072282 metanephric nephron tubule morphogenesis(GO:0072282)
0.6 5.6 GO:0042407 cristae formation(GO:0042407)
0.6 6.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.6 20.5 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.5 5.5 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.5 2.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.5 3.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.5 4.3 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.5 4.3 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.5 3.7 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.5 1.0 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.5 6.2 GO:0006825 copper ion transport(GO:0006825)
0.5 21.0 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.5 5.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.5 7.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.5 11.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.5 4.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.5 36.0 GO:0045454 cell redox homeostasis(GO:0045454)
0.5 3.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.5 5.0 GO:0051451 myoblast migration(GO:0051451)
0.5 12.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.5 2.0 GO:0003409 optic cup structural organization(GO:0003409)
0.5 1.5 GO:0061110 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.5 2.9 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.5 33.5 GO:0007062 sister chromatid cohesion(GO:0007062)
0.5 3.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.5 25.5 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.5 6.2 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.5 1.9 GO:0044351 macropinocytosis(GO:0044351)
0.5 1.4 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.5 5.2 GO:0015886 heme transport(GO:0015886)
0.5 1.4 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.5 11.7 GO:0009235 cobalamin metabolic process(GO:0009235)
0.5 4.6 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.5 2.8 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.5 3.7 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.5 1.8 GO:0061046 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.5 1.8 GO:1900193 regulation of oocyte maturation(GO:1900193) negative regulation of oocyte maturation(GO:1900194)
0.5 3.2 GO:0030091 protein repair(GO:0030091)
0.4 6.6 GO:0002227 innate immune response in mucosa(GO:0002227)
0.4 3.5 GO:0051591 response to cAMP(GO:0051591)
0.4 2.6 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.4 3.0 GO:0007097 nuclear migration(GO:0007097)
0.4 4.2 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.4 5.8 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.4 3.7 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.4 2.1 GO:0048839 inner ear development(GO:0048839)
0.4 8.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.4 4.0 GO:0070365 hepatocyte differentiation(GO:0070365)
0.4 2.0 GO:0034334 adherens junction maintenance(GO:0034334)
0.4 2.8 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.4 5.5 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.4 1.2 GO:0033194 response to hydroperoxide(GO:0033194)
0.4 4.7 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.4 8.8 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.4 1.9 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.4 23.0 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.4 1.5 GO:0006783 heme biosynthetic process(GO:0006783)
0.4 6.7 GO:0035855 megakaryocyte development(GO:0035855)
0.4 4.7 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.4 2.1 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.4 16.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.3 8.9 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.3 5.1 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.3 4.1 GO:0019321 pentose metabolic process(GO:0019321)
0.3 4.3 GO:0031648 protein destabilization(GO:0031648)
0.3 2.9 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.3 1.3 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.3 1.0 GO:0070244 negative regulation of thymocyte apoptotic process(GO:0070244)
0.3 1.9 GO:0071569 protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.3 2.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.3 5.1 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.3 1.6 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.3 0.6 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.3 0.9 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.3 5.1 GO:0048255 mRNA stabilization(GO:0048255)
0.3 9.0 GO:0043304 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.3 4.2 GO:0006020 inositol metabolic process(GO:0006020)
0.3 2.4 GO:0048733 sebaceous gland development(GO:0048733)
0.3 0.9 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.3 9.2 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.3 32.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.3 11.4 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.3 5.8 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.3 4.0 GO:0007567 parturition(GO:0007567)
0.3 7.1 GO:0050873 brown fat cell differentiation(GO:0050873)
0.3 7.9 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.3 1.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.3 6.5 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.3 0.8 GO:0032875 regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
0.3 0.5 GO:1904504 lipophagy(GO:0061724) regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.3 1.6 GO:0046548 retinal rod cell development(GO:0046548)
0.3 3.5 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.2 4.7 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.2 3.7 GO:0033081 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.2 4.5 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.2 3.2 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.2 0.2 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.2 9.8 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.2 0.7 GO:1902938 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.2 19.2 GO:0006334 nucleosome assembly(GO:0006334)
0.2 3.8 GO:0071294 cellular response to zinc ion(GO:0071294)
0.2 3.2 GO:0060117 auditory receptor cell development(GO:0060117)
0.2 12.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.2 14.3 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.2 2.0 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.2 5.0 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.2 0.8 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.2 6.3 GO:0051972 regulation of telomerase activity(GO:0051972)
0.2 8.1 GO:0002576 platelet degranulation(GO:0002576)
0.2 14.0 GO:0043488 regulation of mRNA stability(GO:0043488)
0.2 2.9 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.2 1.0 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.2 1.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 4.2 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.2 6.0 GO:0007340 acrosome reaction(GO:0007340)
0.2 1.2 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.2 10.4 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.2 1.4 GO:0070305 response to cGMP(GO:0070305)
0.2 14.8 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.2 1.0 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.2 10.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.2 1.5 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.2 6.8 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.2 19.7 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.2 0.5 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.2 2.1 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.2 1.1 GO:0070986 left/right axis specification(GO:0070986)
0.2 4.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.2 1.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.2 0.5 GO:1903121 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.2 0.3 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.2 2.5 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.2 12.9 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.2 1.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.2 0.8 GO:0060356 leucine import(GO:0060356)
0.2 2.6 GO:0032098 regulation of appetite(GO:0032098)
0.2 0.5 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.1 0.6 GO:0048295 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293) positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.1 3.8 GO:0006739 NADP metabolic process(GO:0006739)
0.1 2.8 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.6 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.1 0.4 GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332)
0.1 5.0 GO:0021795 cerebral cortex cell migration(GO:0021795)
0.1 11.3 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.1 1.8 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.1 1.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.4 GO:0061743 motor learning(GO:0061743)
0.1 6.7 GO:0045333 cellular respiration(GO:0045333)
0.1 1.1 GO:0034138 toll-like receptor 3 signaling pathway(GO:0034138)
0.1 0.9 GO:0003360 brainstem development(GO:0003360)
0.1 7.8 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 1.2 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1 1.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 1.2 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 1.6 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.1 3.6 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 0.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 5.4 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 0.2 GO:2000321 positive regulation of T-helper 17 type immune response(GO:2000318) positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.1 1.5 GO:0046676 negative regulation of insulin secretion(GO:0046676) negative regulation of peptide hormone secretion(GO:0090278)
0.1 4.5 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.1 3.9 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.1 6.0 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.1 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 5.9 GO:0006903 vesicle targeting(GO:0006903)
0.1 1.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 4.3 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.1 0.8 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 0.2 GO:0048840 otolith development(GO:0048840)
0.1 5.3 GO:0034332 adherens junction organization(GO:0034332)
0.1 0.1 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.1 1.0 GO:0007398 ectoderm development(GO:0007398)
0.1 0.9 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 1.7 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.1 0.6 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.1 4.7 GO:0000910 cytokinesis(GO:0000910)
0.1 1.0 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.5 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.8 GO:1904888 cranial skeletal system development(GO:1904888)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 1.8 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.7 GO:0031167 rRNA methylation(GO:0031167)
0.0 2.2 GO:0008344 adult locomotory behavior(GO:0008344)
0.0 0.3 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.4 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.0 0.3 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.2 GO:0009886 post-embryonic morphogenesis(GO:0009886)
0.0 0.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0090003 regulation of establishment of protein localization to plasma membrane(GO:0090003)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722) glycerol transport(GO:0015793)
0.0 0.1 GO:0003095 pressure natriuresis(GO:0003095)
0.0 0.1 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.4 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.4 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0009642 response to light intensity(GO:0009642)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
14.7 58.9 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
11.9 35.8 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
11.3 22.6 GO:0032432 actin filament bundle(GO:0032432)
8.4 58.9 GO:0044326 dendritic spine neck(GO:0044326)
8.3 33.1 GO:1990423 RZZ complex(GO:1990423)
7.9 39.7 GO:0071986 Ragulator complex(GO:0071986)
7.7 23.2 GO:0031372 UBC13-MMS2 complex(GO:0031372)
7.7 30.6 GO:0000811 GINS complex(GO:0000811)
7.5 59.6 GO:0016012 sarcoglycan complex(GO:0016012)
7.3 36.5 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
7.2 21.6 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
7.1 21.4 GO:0005588 collagen type V trimer(GO:0005588)
6.7 20.2 GO:0035370 UBC13-UEV1A complex(GO:0035370)
6.7 47.0 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
6.3 81.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
6.2 18.5 GO:0002079 inner acrosomal membrane(GO:0002079)
6.1 48.9 GO:0070761 pre-snoRNP complex(GO:0070761)
6.1 36.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
6.0 24.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
5.9 94.4 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
5.9 29.4 GO:0032021 NELF complex(GO:0032021)
5.3 21.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
5.2 41.9 GO:0097504 Gemini of coiled bodies(GO:0097504)
5.2 62.4 GO:0031595 nuclear proteasome complex(GO:0031595)
5.1 15.3 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
5.1 15.2 GO:0034455 t-UTP complex(GO:0034455)
5.0 15.0 GO:0030289 protein phosphatase 4 complex(GO:0030289)
4.8 28.9 GO:0031298 replication fork protection complex(GO:0031298)
4.7 9.4 GO:0002081 outer acrosomal membrane(GO:0002081)
4.6 73.8 GO:0031080 nuclear pore outer ring(GO:0031080)
4.6 41.4 GO:0005827 polar microtubule(GO:0005827)
4.5 13.6 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
4.5 17.8 GO:0044611 nuclear pore inner ring(GO:0044611)
3.9 19.3 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
3.8 42.2 GO:0005688 U6 snRNP(GO:0005688)
3.8 11.4 GO:0031262 Ndc80 complex(GO:0031262)
3.6 25.0 GO:0005785 signal recognition particle receptor complex(GO:0005785)
3.5 17.6 GO:0071148 TEAD-1-YAP complex(GO:0071148)
3.4 20.5 GO:0001740 Barr body(GO:0001740)
3.4 17.0 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
3.4 20.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
3.4 26.9 GO:0070552 BRISC complex(GO:0070552)
3.3 30.0 GO:0033588 Elongator holoenzyme complex(GO:0033588)
3.3 16.4 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
3.3 13.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
3.1 27.8 GO:0005638 lamin filament(GO:0005638)
3.1 9.2 GO:0032302 MutSbeta complex(GO:0032302)
3.0 9.1 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
3.0 8.9 GO:0071159 NF-kappaB complex(GO:0071159)
3.0 14.9 GO:0097149 centralspindlin complex(GO:0097149)
2.9 38.0 GO:0097470 ribbon synapse(GO:0097470)
2.9 22.9 GO:0032133 chromosome passenger complex(GO:0032133)
2.9 8.6 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
2.9 28.5 GO:0000796 condensin complex(GO:0000796)
2.8 47.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
2.7 68.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
2.6 23.3 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
2.6 25.5 GO:0030126 COPI vesicle coat(GO:0030126)
2.5 25.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
2.5 45.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
2.5 17.5 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
2.5 74.9 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
2.4 22.0 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
2.4 28.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
2.4 28.8 GO:0045120 pronucleus(GO:0045120)
2.4 35.8 GO:0097431 mitotic spindle pole(GO:0097431)
2.3 23.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
2.3 11.3 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
2.2 52.6 GO:0035371 microtubule plus-end(GO:0035371)
2.2 41.2 GO:0036020 endolysosome membrane(GO:0036020)
2.2 8.7 GO:0001405 presequence translocase-associated import motor(GO:0001405)
2.1 27.6 GO:0000243 commitment complex(GO:0000243)
2.1 8.2 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
2.0 18.4 GO:0071438 invadopodium membrane(GO:0071438)
2.0 24.3 GO:0005642 annulate lamellae(GO:0005642)
2.0 4.0 GO:0012505 endomembrane system(GO:0012505)
2.0 8.0 GO:0005846 nuclear cap binding complex(GO:0005846)
2.0 37.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
2.0 9.8 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
2.0 37.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
1.9 13.6 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
1.9 11.6 GO:0008537 proteasome activator complex(GO:0008537)
1.9 13.5 GO:0005955 calcineurin complex(GO:0005955)
1.9 26.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
1.9 28.0 GO:0032433 filopodium tip(GO:0032433)
1.8 38.8 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
1.8 3.7 GO:0035869 ciliary transition zone(GO:0035869)
1.8 7.3 GO:1990730 VCP-NSFL1C complex(GO:1990730)
1.8 14.3 GO:0097255 R2TP complex(GO:0097255)
1.8 48.3 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
1.7 15.7 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
1.7 7.0 GO:0030896 checkpoint clamp complex(GO:0030896)
1.7 13.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
1.7 16.5 GO:0000439 core TFIIH complex(GO:0000439)
1.6 11.5 GO:0071203 WASH complex(GO:0071203)
1.6 62.4 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
1.6 27.8 GO:0005839 proteasome core complex(GO:0005839)
1.6 11.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
1.6 4.8 GO:0030906 retromer, cargo-selective complex(GO:0030906)
1.6 11.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
1.6 6.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
1.6 20.5 GO:0000815 ESCRT III complex(GO:0000815)
1.6 6.3 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
1.5 7.7 GO:0070847 core mediator complex(GO:0070847)
1.5 89.4 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
1.5 14.9 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
1.4 7.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
1.4 10.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
1.4 12.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
1.4 22.5 GO:0033276 transcription factor TFTC complex(GO:0033276)
1.4 18.1 GO:0030677 ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
1.4 12.4 GO:0061574 ASAP complex(GO:0061574)
1.3 8.1 GO:0033061 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
1.3 6.7 GO:0044530 supraspliceosomal complex(GO:0044530)
1.3 18.7 GO:0017119 Golgi transport complex(GO:0017119)
1.3 9.2 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
1.3 18.0 GO:0001673 male germ cell nucleus(GO:0001673)
1.3 10.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
1.3 22.7 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
1.3 21.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
1.3 3.8 GO:0070557 PCNA-p21 complex(GO:0070557)
1.3 16.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) MCM complex(GO:0042555)
1.2 8.7 GO:0044194 cytolytic granule(GO:0044194)
1.2 8.7 GO:0030870 Mre11 complex(GO:0030870)
1.2 13.4 GO:0035686 sperm fibrous sheath(GO:0035686)
1.2 17.1 GO:0044754 autolysosome(GO:0044754)
1.2 26.0 GO:0032591 dendritic spine membrane(GO:0032591)
1.2 4.7 GO:0008275 gamma-tubulin small complex(GO:0008275)
1.2 65.7 GO:0045171 intercellular bridge(GO:0045171)
1.2 16.4 GO:0008091 spectrin(GO:0008091)
1.1 7.9 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
1.1 3.2 GO:0043291 RAVE complex(GO:0043291)
1.0 74.9 GO:0000777 condensed chromosome kinetochore(GO:0000777)
1.0 13.2 GO:0030478 actin cap(GO:0030478)
1.0 51.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
1.0 9.7 GO:0090543 Flemming body(GO:0090543)
1.0 19.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
1.0 6.7 GO:0033269 internode region of axon(GO:0033269)
0.9 7.4 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.9 16.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.9 25.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.9 90.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.9 7.8 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.9 3.5 GO:0031085 BLOC-3 complex(GO:0031085)
0.9 0.9 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.8 6.7 GO:0005869 dynactin complex(GO:0005869)
0.8 3.3 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.8 23.2 GO:0031143 pseudopodium(GO:0031143)
0.8 23.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.8 3.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.8 7.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.8 8.8 GO:0030008 TRAPP complex(GO:0030008)
0.8 5.6 GO:0061617 MICOS complex(GO:0061617)
0.8 16.8 GO:0000922 spindle pole(GO:0000922)
0.8 37.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.8 18.2 GO:0000776 kinetochore(GO:0000776)
0.8 20.4 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.8 10.0 GO:0016600 flotillin complex(GO:0016600)
0.7 1.5 GO:0070939 Dsl1p complex(GO:0070939)
0.7 4.4 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.7 12.5 GO:0097228 sperm principal piece(GO:0097228)
0.7 21.8 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.7 12.3 GO:0031932 TORC2 complex(GO:0031932)
0.7 70.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.7 5.3 GO:0005915 zonula adherens(GO:0005915)
0.7 20.9 GO:0008180 COP9 signalosome(GO:0008180)
0.7 22.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.6 3.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.6 18.0 GO:0000502 proteasome complex(GO:0000502)
0.6 3.1 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.6 14.0 GO:0030686 90S preribosome(GO:0030686)
0.6 10.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.6 10.1 GO:0000145 exocyst(GO:0000145)
0.6 29.1 GO:0002102 podosome(GO:0002102)
0.6 4.0 GO:0000812 Swr1 complex(GO:0000812)
0.5 15.4 GO:0031941 filamentous actin(GO:0031941)
0.5 1.0 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.5 6.7 GO:0031209 SCAR complex(GO:0031209)
0.5 2.0 GO:0031417 NatC complex(GO:0031417)
0.5 5.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.5 3.5 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.5 65.4 GO:0001650 fibrillar center(GO:0001650)
0.5 51.2 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.5 3.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.5 4.8 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.5 2.4 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.5 16.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.5 14.0 GO:0016592 mediator complex(GO:0016592)
0.4 109.9 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.4 10.7 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.4 7.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.4 7.0 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.4 2.6 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.4 4.3 GO:0051233 spindle midzone(GO:0051233)
0.4 13.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.4 3.8 GO:0032039 integrator complex(GO:0032039)
0.4 45.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.4 8.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.4 31.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.4 1.6 GO:0035838 growing cell tip(GO:0035838)
0.4 27.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.4 5.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.4 7.6 GO:0005876 spindle microtubule(GO:0005876)
0.4 3.2 GO:0032420 stereocilium(GO:0032420)
0.3 29.0 GO:0000793 condensed chromosome(GO:0000793)
0.3 37.2 GO:0005903 brush border(GO:0005903)
0.3 48.4 GO:0005795 Golgi stack(GO:0005795)
0.3 35.2 GO:0005802 trans-Golgi network(GO:0005802)
0.3 2.3 GO:0019908 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.3 1.6 GO:0005577 fibrinogen complex(GO:0005577)
0.3 53.3 GO:0005938 cell cortex(GO:0005938)
0.2 1.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 3.0 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.2 14.7 GO:0019866 organelle inner membrane(GO:0019866)
0.2 8.8 GO:0044216 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.2 0.6 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.2 1.0 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.2 0.6 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.2 1.8 GO:0030056 hemidesmosome(GO:0030056)
0.2 0.9 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.2 3.0 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.2 0.5 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.2 4.4 GO:0031966 mitochondrial membrane(GO:0031966)
0.1 13.5 GO:0031968 organelle outer membrane(GO:0031968)
0.1 0.4 GO:0032279 asymmetric synapse(GO:0032279)
0.1 0.4 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 10.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.5 GO:0031211 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 7.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.5 GO:0019867 outer membrane(GO:0019867)
0.1 2.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 2.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 9.3 GO:0005882 intermediate filament(GO:0005882)
0.1 1.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 12.7 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1 1.9 GO:0005844 polysome(GO:0005844)
0.1 4.1 GO:0031519 PcG protein complex(GO:0031519)
0.1 33.0 GO:0005635 nuclear envelope(GO:0005635)
0.1 0.4 GO:1990031 pinceau fiber(GO:1990031)
0.1 4.0 GO:0044815 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.1 2.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 35.6 GO:0005730 nucleolus(GO:0005730)
0.1 2.8 GO:0030027 lamellipodium(GO:0030027)
0.1 0.3 GO:0033263 CORVET complex(GO:0033263)
0.1 21.1 GO:0016607 nuclear speck(GO:0016607)
0.1 8.3 GO:0044420 extracellular matrix component(GO:0044420)
0.0 0.2 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 2.1 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.5 GO:0005840 ribosome(GO:0005840)
0.0 0.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.0 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.1 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 23.9 GO:0005654 nucleoplasm(GO:0005654)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
23.8 71.5 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
10.5 41.8 GO:0031208 POZ domain binding(GO:0031208)
10.0 29.9 GO:0005047 signal recognition particle binding(GO:0005047)
9.1 27.2 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
7.2 21.6 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
7.0 41.9 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
6.6 66.3 GO:0019237 centromeric DNA binding(GO:0019237)
6.6 39.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
6.3 19.0 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
6.3 25.1 GO:0004594 pantothenate kinase activity(GO:0004594)
6.3 18.8 GO:0000035 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
6.1 72.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
5.9 17.8 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
5.8 17.5 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
5.7 62.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
5.5 22.0 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
5.4 38.0 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
5.4 32.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
5.3 21.0 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
5.2 15.7 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
5.1 25.7 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
5.0 30.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
4.8 38.5 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
4.5 62.7 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
4.4 30.7 GO:0061133 endopeptidase activator activity(GO:0061133)
4.3 43.4 GO:0042731 PH domain binding(GO:0042731)
4.2 33.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
4.2 33.4 GO:0000182 rDNA binding(GO:0000182)
4.1 70.0 GO:0008494 translation activator activity(GO:0008494)
4.0 8.1 GO:0001540 beta-amyloid binding(GO:0001540)
4.0 24.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
3.7 11.2 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
3.7 110.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
3.6 14.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
3.5 17.7 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
3.5 14.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
3.4 13.5 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
3.3 68.5 GO:0001055 RNA polymerase II activity(GO:0001055)
3.2 9.7 GO:0032089 NACHT domain binding(GO:0032089)
3.2 19.1 GO:0042296 ISG15 transferase activity(GO:0042296)
3.2 12.7 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
3.1 22.0 GO:0004849 uridine kinase activity(GO:0004849)
3.0 27.4 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
3.0 9.0 GO:0032427 GBD domain binding(GO:0032427)
2.9 14.7 GO:0070905 serine binding(GO:0070905)
2.9 8.8 GO:0004832 valine-tRNA ligase activity(GO:0004832)
2.9 28.9 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
2.8 11.3 GO:0043515 kinetochore binding(GO:0043515)
2.8 2.8 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
2.8 11.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
2.8 47.2 GO:0008432 JUN kinase binding(GO:0008432)
2.7 8.2 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
2.7 5.4 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
2.7 27.1 GO:0046790 virion binding(GO:0046790)
2.6 13.2 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
2.6 20.8 GO:0019871 sodium channel inhibitor activity(GO:0019871)
2.6 36.3 GO:0016018 cyclosporin A binding(GO:0016018)
2.6 15.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
2.6 12.9 GO:0070404 NADH binding(GO:0070404)
2.6 100.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
2.6 7.7 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
2.5 35.5 GO:1990825 sequence-specific mRNA binding(GO:1990825)
2.5 14.8 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
2.5 36.9 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
2.5 7.4 GO:0004924 oncostatin-M receptor activity(GO:0004924)
2.4 7.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
2.4 14.3 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
2.4 66.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
2.4 9.4 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
2.3 37.1 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
2.3 9.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
2.3 13.7 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
2.3 11.3 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
2.2 15.7 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
2.2 34.6 GO:0004526 ribonuclease P activity(GO:0004526)
2.1 16.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
2.1 6.3 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
2.1 60.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
2.1 10.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
2.1 18.6 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
2.1 10.3 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
2.0 8.1 GO:0042809 vitamin D receptor binding(GO:0042809)
2.0 6.0 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
2.0 10.1 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
2.0 10.0 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
1.9 52.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
1.9 5.8 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
1.9 5.7 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
1.9 11.3 GO:0004167 dopachrome isomerase activity(GO:0004167)
1.9 5.6 GO:0004730 pseudouridylate synthase activity(GO:0004730)
1.8 40.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
1.8 18.2 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
1.8 92.9 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
1.8 19.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
1.8 10.6 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
1.7 7.0 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
1.7 8.7 GO:0030348 syntaxin-3 binding(GO:0030348)
1.7 8.6 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
1.7 8.6 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
1.7 8.6 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
1.7 18.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
1.7 64.8 GO:0031369 translation initiation factor binding(GO:0031369)
1.7 28.9 GO:0008266 poly(U) RNA binding(GO:0008266)
1.7 15.1 GO:0035174 histone serine kinase activity(GO:0035174)
1.7 23.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
1.6 47.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
1.6 8.0 GO:0061665 SUMO ligase activity(GO:0061665)
1.6 7.9 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
1.6 14.2 GO:0070883 pre-miRNA binding(GO:0070883)
1.6 7.8 GO:0004905 type I interferon receptor activity(GO:0004905)
1.5 6.0 GO:0004566 beta-glucuronidase activity(GO:0004566)
1.5 8.9 GO:0032357 oxidized purine DNA binding(GO:0032357)
1.4 4.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
1.4 1.4 GO:0045295 gamma-catenin binding(GO:0045295)
1.4 34.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
1.4 5.7 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
1.4 15.7 GO:0048156 tau protein binding(GO:0048156)
1.4 8.5 GO:0044547 DNA topoisomerase binding(GO:0044547)
1.4 16.9 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
1.4 39.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
1.4 4.1 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
1.4 8.3 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
1.4 13.6 GO:0019784 NEDD8-specific protease activity(GO:0019784)
1.4 10.8 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
1.3 8.0 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
1.3 4.0 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
1.3 8.0 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
1.3 46.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
1.3 2.6 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
1.3 34.0 GO:0070064 proline-rich region binding(GO:0070064)
1.2 6.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
1.2 4.9 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
1.2 3.7 GO:0051059 NF-kappaB binding(GO:0051059)
1.2 91.4 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
1.2 18.2 GO:0003688 DNA replication origin binding(GO:0003688)
1.2 7.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
1.2 22.3 GO:0070840 dynein complex binding(GO:0070840)
1.2 4.7 GO:0035671 enone reductase activity(GO:0035671)
1.2 47.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
1.1 20.7 GO:0031402 sodium ion binding(GO:0031402)
1.1 3.4 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
1.1 4.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
1.1 3.4 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
1.1 12.2 GO:0015266 protein channel activity(GO:0015266)
1.1 25.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
1.1 9.7 GO:1901612 cardiolipin binding(GO:1901612)
1.1 16.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
1.1 2.1 GO:0016778 diphosphotransferase activity(GO:0016778)
1.1 7.5 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
1.1 3.2 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
1.0 44.5 GO:0003743 translation initiation factor activity(GO:0003743)
1.0 74.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
1.0 27.7 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.0 9.2 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
1.0 6.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
1.0 8.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
1.0 6.0 GO:0035374 chondroitin sulfate binding(GO:0035374)
1.0 6.9 GO:0045545 syndecan binding(GO:0045545)
1.0 24.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
1.0 19.6 GO:0051010 microtubule plus-end binding(GO:0051010)
1.0 10.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.9 3.8 GO:0032190 acrosin binding(GO:0032190)
0.9 23.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.9 14.1 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.9 28.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.9 13.8 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.9 7.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.9 4.6 GO:0008097 5S rRNA binding(GO:0008097)
0.9 1.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.9 90.0 GO:0003697 single-stranded DNA binding(GO:0003697)
0.9 6.2 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.9 3.5 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.9 20.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.9 2.6 GO:0070644 vitamin D response element binding(GO:0070644)
0.8 8.5 GO:0004312 fatty acid synthase activity(GO:0004312)
0.8 4.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.8 3.3 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.8 10.0 GO:0017049 GTP-Rho binding(GO:0017049)
0.8 4.9 GO:0050692 DBD domain binding(GO:0050692)
0.8 8.8 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.8 0.8 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.8 7.9 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.8 33.7 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.8 5.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.8 9.3 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.8 155.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.7 1.5 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.7 11.2 GO:0050811 GABA receptor binding(GO:0050811)
0.7 4.4 GO:0019776 Atg8 ligase activity(GO:0019776)
0.7 4.4 GO:0016421 CoA carboxylase activity(GO:0016421)
0.7 11.6 GO:0070628 proteasome binding(GO:0070628)
0.7 11.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.7 2.9 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.7 2.9 GO:0005499 vitamin D binding(GO:0005499)
0.7 18.3 GO:0005523 tropomyosin binding(GO:0005523)
0.7 2.1 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.7 6.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.7 4.9 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.7 3.5 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.7 2.1 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.7 3.4 GO:0031013 troponin I binding(GO:0031013)
0.7 4.7 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.7 11.4 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.7 2.0 GO:0032184 SUMO polymer binding(GO:0032184)
0.7 68.0 GO:0008565 protein transporter activity(GO:0008565)
0.7 45.2 GO:0032947 protein complex scaffold(GO:0032947)
0.7 19.8 GO:0001848 complement binding(GO:0001848)
0.7 55.3 GO:0070491 repressing transcription factor binding(GO:0070491)
0.7 22.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.6 12.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.6 135.3 GO:0051015 actin filament binding(GO:0051015)
0.6 12.6 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.6 6.9 GO:0050700 CARD domain binding(GO:0050700)
0.6 21.8 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.6 10.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.6 11.1 GO:0070300 phosphatidic acid binding(GO:0070300)
0.6 7.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.6 6.6 GO:0033038 bitter taste receptor activity(GO:0033038)
0.6 1.8 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.6 1.7 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.6 2.3 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.5 1.6 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.5 8.7 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.5 13.5 GO:0015248 sterol transporter activity(GO:0015248)
0.5 3.2 GO:0004673 phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673)
0.5 3.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.5 26.5 GO:0030276 clathrin binding(GO:0030276)
0.5 5.2 GO:0015232 heme transporter activity(GO:0015232)
0.5 14.0 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.5 7.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.5 10.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.5 8.5 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.5 4.9 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.5 7.4 GO:0070513 death domain binding(GO:0070513)
0.5 5.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.4 8.4 GO:0004697 protein kinase C activity(GO:0004697)
0.4 8.7 GO:0004386 helicase activity(GO:0004386)
0.4 2.6 GO:0036310 annealing helicase activity(GO:0036310)
0.4 3.1 GO:0016015 morphogen activity(GO:0016015)
0.4 14.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.4 1.3 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.4 4.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.4 8.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.4 1.3 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.4 10.1 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.4 5.1 GO:0031386 protein tag(GO:0031386)
0.4 31.4 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.4 1.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.4 1.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.4 2.8 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.4 3.8 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.4 19.3 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.4 7.8 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.4 12.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.4 6.0 GO:0005537 mannose binding(GO:0005537)
0.4 8.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.3 4.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.3 2.6 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.3 1.3 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.3 1.3 GO:0004046 aminoacylase activity(GO:0004046)
0.3 0.6 GO:0098770 FBXO family protein binding(GO:0098770)
0.3 4.9 GO:0001972 retinoic acid binding(GO:0001972)
0.3 23.6 GO:0008013 beta-catenin binding(GO:0008013)
0.3 6.8 GO:0016859 cis-trans isomerase activity(GO:0016859)
0.3 2.9 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.3 21.3 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.3 1.9 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3 4.7 GO:0003680 AT DNA binding(GO:0003680)
0.3 11.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.3 7.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.3 32.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.3 5.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 5.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 1.5 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.2 1.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 12.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 24.3 GO:0042393 histone binding(GO:0042393)
0.2 0.7 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.2 2.1 GO:0008301 DNA binding, bending(GO:0008301)
0.2 19.3 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.2 3.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2 14.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.2 10.9 GO:0043130 ubiquitin binding(GO:0043130)
0.2 1.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 14.1 GO:0008186 RNA-dependent ATPase activity(GO:0008186)
0.2 0.4 GO:1990763 arrestin family protein binding(GO:1990763)
0.2 4.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 18.8 GO:0031072 heat shock protein binding(GO:0031072)
0.2 0.8 GO:0019003 GDP binding(GO:0019003)
0.2 0.8 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 0.6 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.2 4.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 0.6 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.2 15.0 GO:0046332 SMAD binding(GO:0046332)
0.2 60.5 GO:0003924 GTPase activity(GO:0003924)
0.2 12.3 GO:0047485 protein N-terminus binding(GO:0047485)
0.2 2.1 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.2 3.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 0.5 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 0.9 GO:0016882 cyclo-ligase activity(GO:0016882)
0.2 2.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 4.1 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.2 42.9 GO:0045296 cadherin binding(GO:0045296)
0.2 2.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 168.4 GO:0003723 RNA binding(GO:0003723)
0.2 4.2 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 0.3 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 1.7 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 3.1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 1.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.9 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 3.5 GO:0050699 WW domain binding(GO:0050699)
0.1 0.4 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 1.5 GO:0070063 RNA polymerase binding(GO:0070063)
0.1 5.5 GO:0005507 copper ion binding(GO:0005507)
0.1 2.9 GO:0003684 damaged DNA binding(GO:0003684)
0.1 1.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 3.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 2.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.5 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.1 0.3 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.1 0.6 GO:0017166 vinculin binding(GO:0017166)
0.1 2.1 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.1 1.5 GO:0030332 cyclin binding(GO:0030332)
0.1 0.3 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.8 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.5 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 1.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0032052 bile acid binding(GO:0032052)
0.0 0.5 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.4 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.2 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.2 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 153.3 PID AURORA B PATHWAY Aurora B signaling
1.7 25.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
1.6 85.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
1.6 80.0 PID MYC PATHWAY C-MYC pathway
1.4 25.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
1.3 10.3 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
1.1 27.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
1.0 75.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.9 33.8 PID NECTIN PATHWAY Nectin adhesion pathway
0.9 22.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.9 18.9 PID ARF 3PATHWAY Arf1 pathway
0.9 34.0 PID IL1 PATHWAY IL1-mediated signaling events
0.8 53.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.8 4.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.8 35.6 PID ATR PATHWAY ATR signaling pathway
0.8 32.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.8 14.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.7 38.7 PID PLK1 PATHWAY PLK1 signaling events
0.7 6.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.7 16.9 PID BARD1 PATHWAY BARD1 signaling events
0.6 14.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.6 44.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.6 51.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.6 5.9 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.6 29.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.6 26.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.5 9.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.5 5.4 PID ATM PATHWAY ATM pathway
0.5 38.6 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.5 10.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.4 21.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.4 15.6 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.4 3.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.4 23.3 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.4 33.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.4 29.9 PID E2F PATHWAY E2F transcription factor network
0.4 33.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.4 11.1 PID NCADHERIN PATHWAY N-cadherin signaling events
0.4 37.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.4 11.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.3 14.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.3 10.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.3 21.0 PID CMYB PATHWAY C-MYB transcription factor network
0.3 4.0 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.3 8.5 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.3 9.7 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.3 3.8 ST GAQ PATHWAY G alpha q Pathway
0.3 13.7 PID AP1 PATHWAY AP-1 transcription factor network
0.3 7.1 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.3 12.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.3 6.7 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.3 23.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.3 1.8 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.3 2.8 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.2 9.7 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.2 7.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.2 3.5 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.2 3.9 PID NETRIN PATHWAY Netrin-mediated signaling events
0.2 3.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.2 6.0 PID NOTCH PATHWAY Notch signaling pathway
0.2 6.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.2 5.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 1.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 3.8 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 3.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 158.7 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
4.3 56.2 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
3.8 99.5 REACTOME KINESINS Genes involved in Kinesins
3.6 58.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
3.5 382.1 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
3.3 29.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
3.1 74.9 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
3.1 119.5 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
3.0 44.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
2.6 57.0 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
2.6 43.6 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
2.4 48.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
2.4 80.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
2.3 32.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
2.2 75.6 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
2.2 15.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
2.1 19.1 REACTOME ORC1 REMOVAL FROM CHROMATIN Genes involved in Orc1 removal from chromatin
2.0 75.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
2.0 173.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
2.0 41.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
2.0 97.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
2.0 152.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
1.8 25.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
1.8 30.9 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
1.8 52.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
1.8 44.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
1.7 24.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
1.7 13.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
1.6 22.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
1.5 38.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
1.5 21.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
1.5 53.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
1.4 53.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
1.4 85.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
1.4 44.9 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
1.3 33.9 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
1.2 19.8 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
1.2 32.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
1.2 39.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
1.2 30.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
1.1 84.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
1.1 12.7 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
1.0 17.8 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.9 152.9 REACTOME TRANSLATION Genes involved in Translation
0.9 13.7 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.9 27.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.8 13.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.8 16.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.8 125.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.8 15.0 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.7 16.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.7 17.9 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.7 7.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.6 7.8 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.6 16.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.6 4.5 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.6 18.9 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.6 23.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.6 15.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.5 21.6 REACTOME RNA POL III TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.5 4.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.5 22.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.5 27.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.5 3.0 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.5 12.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.5 1.9 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.5 10.8 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.5 9.5 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.4 5.4 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.4 4.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.4 27.6 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.4 8.0 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.4 46.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.4 0.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.4 8.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.4 24.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.4 6.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.4 6.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.4 29.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.3 17.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.3 4.6 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.3 5.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.3 8.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 1.9 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.2 9.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.2 3.5 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.2 6.4 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.2 12.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.2 4.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2 2.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 5.1 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.2 15.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 7.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.2 1.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.2 10.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 5.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.8 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 2.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 6.2 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.1 2.8 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 2.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 1.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.0 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.8 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 4.3 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.1 2.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.5 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 1.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.0 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 2.1 REACTOME OPIOID SIGNALLING Genes involved in Opioid Signalling
0.0 0.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.3 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.6 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.2 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling