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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for POU5F1_POU2F3

Z-value: 3.15

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Transcription factors associated with POU5F1_POU2F3

Gene Symbol Gene ID Gene Info
ENSG00000204531.11 POU class 5 homeobox 1
ENSG00000137709.5 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU2F3hg19_v2_chr11_+_120107344_1201073510.305.3e-06Click!
POU5F1hg19_v2_chr6_-_31138439_311384750.203.0e-03Click!

Activity profile of POU5F1_POU2F3 motif

Sorted Z-values of POU5F1_POU2F3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_90060377 91.79 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr2_+_90248739 83.44 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr2_+_90139056 83.06 ENST00000492446.1
immunoglobulin kappa variable 1D-16
chr2_-_89399845 82.87 ENST00000479981.1
immunoglobulin kappa variable 1-16
chr2_+_90108504 78.23 ENST00000390271.2
immunoglobulin kappa variable 6D-41 (non-functional)
chr2_+_90077680 75.77 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr14_-_107049312 72.79 ENST00000390627.2
immunoglobulin heavy variable 3-53
chr2_+_89998789 69.92 ENST00000453166.2
immunoglobulin kappa variable 2D-28
chr2_-_89340242 66.20 ENST00000480492.1
immunoglobulin kappa variable 1-12
chr2_+_90121477 64.87 ENST00000483379.1
immunoglobulin kappa variable 1D-17
chr22_+_22786288 63.97 ENST00000390301.2
immunoglobulin lambda variable 1-36
chr2_-_89521942 62.30 ENST00000482769.1
immunoglobulin kappa variable 2-28
chr22_+_23077065 61.74 ENST00000390310.2
immunoglobulin lambda variable 2-18
chr2_+_89975669 61.04 ENST00000474213.1
immunoglobulin kappa variable 2D-30
chr2_-_89442621 59.35 ENST00000492167.1
immunoglobulin kappa variable 3-20
chr14_-_107078851 58.55 ENST00000390628.2
immunoglobulin heavy variable 1-58
chr21_+_10862622 58.42 ENST00000302092.5
ENST00000559480.1
immunoglobulin heavy variable 1/OR21-1 (non-functional)
chr16_+_33605231 56.84 ENST00000570121.2
immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr2_+_90198535 56.54 ENST00000390276.2
immunoglobulin kappa variable 1D-12
chr2_-_89597542 55.48 ENST00000465170.1
immunoglobulin kappa variable 1-37 (non-functional)
chr14_-_106539557 55.36 ENST00000390599.2
immunoglobulin heavy variable 1-8
chr2_-_89266286 54.90 ENST00000464162.1
immunoglobulin kappa variable 1-6
chr2_+_89923550 54.78 ENST00000509129.1
immunoglobulin kappa variable 1D-37 (non-functional)
chr14_-_107083690 54.15 ENST00000455737.1
ENST00000390629.2
immunoglobulin heavy variable 4-59
chr14_-_107095662 52.77 ENST00000390630.2
immunoglobulin heavy variable 4-61
chr2_-_89545079 52.62 ENST00000468494.1
immunoglobulin kappa variable 2-30
chr22_+_23134974 52.13 ENST00000390314.2
immunoglobulin lambda variable 2-11
chr22_+_22707260 51.50 ENST00000390293.1
immunoglobulin lambda variable 5-48 (non-functional)
chr2_-_89459813 50.92 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr16_+_32077386 50.48 ENST00000354689.6
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr14_-_107170409 49.99 ENST00000390633.2
immunoglobulin heavy variable 1-69
chr22_+_22712087 49.92 ENST00000390294.2
immunoglobulin lambda variable 1-47
chr14_-_106552755 49.83 ENST00000390600.2
immunoglobulin heavy variable 3-9
chr2_+_90192768 49.80 ENST00000390275.2
immunoglobulin kappa variable 1D-13
chr2_-_89417335 48.69 ENST00000490686.1
immunoglobulin kappa variable 1-17
chr16_+_33020496 47.78 ENST00000565407.2
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr14_-_106573756 47.13 ENST00000390601.2
immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr14_-_107114267 47.09 ENST00000454421.2
immunoglobulin heavy variable 3-64
chr2_+_90153696 46.89 ENST00000417279.2
immunoglobulin kappa variable 3D-15 (gene/pseudogene)
chr2_+_89890533 45.74 ENST00000429992.2
immunoglobulin kappa variable 2D-40
chr22_+_23063100 45.11 ENST00000390309.2
immunoglobulin lambda variable 3-19
chr22_+_22735135 44.81 ENST00000390297.2
immunoglobulin lambda variable 1-44
chr15_-_22473353 44.00 ENST00000557788.2
immunoglobulin heavy variable 4/OR15-8 (non-functional)
chr22_+_23154239 43.64 ENST00000390315.2
immunoglobulin lambda variable 3-10
chr22_+_23089870 43.36 ENST00000390311.2
immunoglobulin lambda variable 3-16
chr14_-_106733624 43.34 ENST00000390610.2
immunoglobulin heavy variable 1-24
chr4_-_71532339 42.31 ENST00000254801.4
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr2_+_89952792 42.01 ENST00000390265.2
immunoglobulin kappa variable 1D-33
chr2_-_89619904 41.51 ENST00000498574.1
immunoglobulin kappa variable 1-39 (gene/pseudogene)
chr14_-_106830057 40.28 ENST00000390616.2
immunoglobulin heavy variable 4-34
chr16_-_33647696 40.25 ENST00000558425.1
ENST00000569103.2
Uncharacterized protein
chr5_-_172198190 39.05 ENST00000239223.3
dual specificity phosphatase 1
chr16_+_32063311 38.34 ENST00000426099.1
AC142381.1
chr22_+_23165153 38.04 ENST00000390317.2
immunoglobulin lambda variable 2-8
chr2_+_68962014 37.99 ENST00000467265.1
Rho GTPase activating protein 25
chr16_+_23847267 37.64 ENST00000321728.7
protein kinase C, beta
chr14_-_106926724 37.44 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr22_+_23101182 37.41 ENST00000390312.2
immunoglobulin lambda variable 2-14
chr2_+_87565634 37.36 ENST00000421835.2
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr22_+_23040274 37.24 ENST00000390306.2
immunoglobulin lambda variable 2-23
chr10_-_98031265 37.19 ENST00000224337.5
ENST00000371176.2
B-cell linker
chr2_-_90538397 37.10 ENST00000443397.3
Uncharacterized protein
chr2_+_89901292 36.74 ENST00000448155.2
immunoglobulin kappa variable 1D-39
chr10_-_98031310 36.59 ENST00000427367.2
ENST00000413476.2
B-cell linker
chr14_-_106963409 35.74 ENST00000390621.2
immunoglobulin heavy variable 1-45
chr2_+_90273679 35.55 ENST00000423080.2
immunoglobulin kappa variable 3D-7
chr14_-_106845789 35.55 ENST00000390617.2
immunoglobulin heavy variable 3-35 (non-functional)
chr18_-_52989217 34.84 ENST00000570287.2
transcription factor 4
chr14_-_106878083 34.79 ENST00000390619.2
immunoglobulin heavy variable 4-39
chr2_-_89278535 34.52 ENST00000390247.2
immunoglobulin kappa variable 3-7 (non-functional)
chr2_+_89184868 33.76 ENST00000390243.2
immunoglobulin kappa variable 4-1
chr2_-_89327228 33.68 ENST00000483158.1
immunoglobulin kappa variable 3-11
chr16_+_23847339 33.54 ENST00000303531.7
protein kinase C, beta
chr2_+_114163945 33.46 ENST00000453673.3
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr19_-_1021113 33.44 ENST00000333175.5
ENST00000356663.3
transmembrane protein 259
chr14_-_106478603 33.30 ENST00000390596.2
immunoglobulin heavy variable 4-4
chr2_-_89568263 32.56 ENST00000473726.1
immunoglobulin kappa variable 1-33
chr2_+_89986318 31.69 ENST00000491977.1
immunoglobulin kappa variable 2D-29
chr2_+_90458201 31.66 ENST00000603238.1
Uncharacterized protein
chrX_-_106960285 31.36 ENST00000503515.1
ENST00000372397.2
TSC22 domain family, member 3
chr2_-_89385283 31.14 ENST00000390252.2
immunoglobulin kappa variable 3-15
chr2_+_90211643 31.02 ENST00000390277.2
immunoglobulin kappa variable 3D-11
chr16_+_33006369 30.78 ENST00000425181.3
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr6_-_32557610 30.62 ENST00000360004.5
major histocompatibility complex, class II, DR beta 1
chr6_+_32407619 30.02 ENST00000395388.2
ENST00000374982.5
major histocompatibility complex, class II, DR alpha
chr7_-_100183742 29.78 ENST00000310300.6
leucine-rich repeats and calponin homology (CH) domain containing 4
chr12_-_91574142 29.69 ENST00000547937.1
decorin
chr22_+_22764088 28.75 ENST00000390299.2
immunoglobulin lambda variable 1-40
chr1_-_153363452 28.46 ENST00000368732.1
ENST00000368733.3
S100 calcium binding protein A8
chr3_+_186648307 28.13 ENST00000457772.2
ENST00000455441.1
ENST00000427315.1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr22_+_22930626 27.81 ENST00000390302.2
immunoglobulin lambda variable 2-33 (non-functional)
chr6_-_32784687 27.79 ENST00000447394.1
ENST00000438763.2
major histocompatibility complex, class II, DO beta
chr3_+_186648274 27.27 ENST00000169298.3
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr22_+_23046750 27.23 ENST00000390307.2
immunoglobulin lambda variable 3-22 (gene/pseudogene)
chr2_-_89513402 26.93 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr14_-_106994333 26.76 ENST00000390624.2
immunoglobulin heavy variable 3-48
chr2_-_89247338 26.37 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr1_-_149858227 26.31 ENST00000369155.2
histone cluster 2, H2be
chr14_-_106610852 25.90 ENST00000390603.2
immunoglobulin heavy variable 3-15
chr7_+_26438187 25.62 ENST00000439120.1
ENST00000430548.1
ENST00000421862.1
ENST00000449537.1
ENST00000420774.1
ENST00000418758.2
AC004540.5
chr18_-_52989525 25.47 ENST00000457482.3
transcription factor 4
chr14_-_106692191 25.39 ENST00000390607.2
immunoglobulin heavy variable 3-21
chr14_-_106816253 25.13 ENST00000390615.2
immunoglobulin heavy variable 3-33
chr17_-_62009621 25.09 ENST00000349817.2
ENST00000392795.3
CD79b molecule, immunoglobulin-associated beta
chr12_-_91573132 25.02 ENST00000550563.1
ENST00000546370.1
decorin
chr19_+_35820064 24.95 ENST00000341773.6
ENST00000600131.1
ENST00000270311.6
ENST00000595780.1
ENST00000597916.1
ENST00000593867.1
ENST00000600424.1
ENST00000599811.1
ENST00000536635.2
ENST00000085219.5
ENST00000544992.2
ENST00000419549.2
CD22 molecule
chr14_-_106866934 24.87 ENST00000390618.2
immunoglobulin heavy variable 3-38 (non-functional)
chr22_+_23029188 24.80 ENST00000390305.2
immunoglobulin lambda variable 3-25
chr17_-_62009702 24.77 ENST00000006750.3
CD79b molecule, immunoglobulin-associated beta
chr15_-_20193370 24.52 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr18_-_53089723 24.06 ENST00000561992.1
ENST00000562512.2
transcription factor 4
chr14_-_107283278 23.89 ENST00000390639.2
immunoglobulin heavy variable 7-81 (non-functional)
chr22_-_24096562 23.66 ENST00000398465.3
pre-B lymphocyte 3
chr14_-_107131560 23.30 ENST00000390632.2
immunoglobulin heavy variable 3-66
chr3_+_49507674 22.71 ENST00000431960.1
ENST00000452317.1
ENST00000435508.2
ENST00000452060.1
ENST00000428779.1
ENST00000419218.1
ENST00000430636.1
dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr19_-_39108568 22.18 ENST00000586296.1
mitogen-activated protein kinase kinase kinase kinase 1
chr15_-_22448819 21.91 ENST00000604066.1
immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr7_-_130080818 20.88 ENST00000343969.5
ENST00000541543.1
ENST00000489512.1
centrosomal protein 41kDa
chr14_-_107219365 20.86 ENST00000424969.2
immunoglobulin heavy variable 3-74
chr10_-_105452917 20.82 ENST00000427662.2
SH3 and PX domains 2A
chr1_-_153029980 20.26 ENST00000392653.2
small proline-rich protein 2A
chr18_-_53255766 20.24 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
transcription factor 4
chr8_-_134115118 20.16 ENST00000395352.3
ENST00000338087.5
Src-like-adaptor
chr7_-_37024665 20.03 ENST00000396040.2
engulfment and cell motility 1
chr17_-_47841485 19.90 ENST00000506156.1
ENST00000240364.2
family with sequence similarity 117, member A
chr18_-_53257027 19.74 ENST00000568740.1
ENST00000564403.2
ENST00000537578.1
transcription factor 4
chr9_-_35618364 19.33 ENST00000378431.1
ENST00000378430.3
ENST00000259633.4
CD72 molecule
chr19_-_39108552 19.27 ENST00000591517.1
mitogen-activated protein kinase kinase kinase kinase 1
chr1_-_31230650 19.20 ENST00000294507.3
lysosomal protein transmembrane 5
chr16_+_33629600 18.82 ENST00000562905.2
immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr8_+_56792355 18.81 ENST00000519728.1
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr1_-_153013588 18.63 ENST00000360379.3
small proline-rich protein 2D
chr22_-_24096630 18.59 ENST00000248948.3
pre-B lymphocyte 3
chr16_+_90089008 18.37 ENST00000268699.4
growth arrest-specific 8
chr6_+_37137939 18.19 ENST00000373509.5
pim-1 oncogene
chr1_-_153044083 18.04 ENST00000341611.2
small proline-rich protein 2B
chr12_-_91576561 17.99 ENST00000547568.2
ENST00000552962.1
decorin
chr19_+_19144384 17.71 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
armadillo repeat containing 6
chr12_-_91576429 17.49 ENST00000552145.1
ENST00000546745.1
decorin
chr8_+_56792377 17.44 ENST00000520220.2
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr15_-_20170354 17.22 ENST00000338912.5
immunoglobulin heavy variable 1/OR15-9 (non-functional)
chr12_-_123201337 17.12 ENST00000528880.2
hydroxycarboxylic acid receptor 3
chr14_-_106453155 17.00 ENST00000390594.2
immunoglobulin heavy variable 1-2
chr1_+_156119798 16.75 ENST00000355014.2
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr4_-_134070250 16.52 ENST00000505289.1
ENST00000509715.1
RP11-9G1.3
chr19_+_13858593 16.30 ENST00000221554.8
coiled-coil domain containing 130
chr9_-_127533582 16.24 ENST00000416460.2
nuclear receptor subfamily 6, group A, member 1
chr22_+_22936998 16.08 ENST00000390303.2
immunoglobulin lambda variable 3-32 (non-functional)
chr6_-_159421198 16.04 ENST00000252655.1
ENST00000297262.3
ENST00000367069.2
radial spoke 3 homolog (Chlamydomonas)
chr12_-_7245125 16.04 ENST00000542285.1
ENST00000540610.1
complement component 1, r subcomponent
chr14_-_106805716 16.00 ENST00000438142.2
immunoglobulin heavy variable 4-31
chr7_+_100183927 15.83 ENST00000241071.6
ENST00000360609.2
F-box protein 24
chr12_+_25205568 15.61 ENST00000548766.1
ENST00000556887.1
lymphoid-restricted membrane protein
chr9_+_136325089 15.61 ENST00000291722.7
ENST00000316948.4
ENST00000540581.1
calcium channel flower domain containing 1
chr12_+_25205666 15.42 ENST00000547044.1
lymphoid-restricted membrane protein
chr19_-_4723761 15.26 ENST00000597849.1
ENST00000598800.1
ENST00000602161.1
ENST00000597726.1
ENST00000601130.1
ENST00000262960.9
dipeptidyl-peptidase 9
chr12_+_25205446 15.15 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
lymphoid-restricted membrane protein
chr12_-_16761007 15.07 ENST00000354662.1
ENST00000441439.2
LIM domain only 3 (rhombotin-like 2)
chr12_-_6772303 14.65 ENST00000396807.4
ENST00000446105.2
ENST00000341550.4
inhibitor of growth family, member 4
chr19_-_39108643 14.60 ENST00000396857.2
mitogen-activated protein kinase kinase kinase kinase 1
chr14_-_106586656 14.60 ENST00000390602.2
immunoglobulin heavy variable 3-13
chr13_-_99959641 14.33 ENST00000376414.4
G protein-coupled receptor 183
chr18_+_74240610 14.32 ENST00000578092.1
ENST00000578613.1
ENST00000583578.1
long intergenic non-protein coding RNA 908
chr7_-_37488834 14.20 ENST00000310758.4
engulfment and cell motility 1
chr22_+_42229100 14.18 ENST00000361204.4
sterol regulatory element binding transcription factor 2
chr12_-_91576750 14.16 ENST00000228329.5
ENST00000303320.3
ENST00000052754.5
decorin
chr22_+_22550113 14.16 ENST00000390285.3
immunoglobulin lambda variable 6-57
chrX_-_48776292 14.14 ENST00000376509.4
pim-2 oncogene
chr18_+_42260861 14.07 ENST00000282030.5
SET binding protein 1
chr5_+_49961727 13.91 ENST00000505697.2
ENST00000503750.2
ENST00000514342.2
poly (ADP-ribose) polymerase family, member 8
chr12_+_124997766 13.83 ENST00000543970.1
RP11-83B20.1
chr14_-_106622419 13.78 ENST00000390604.2
immunoglobulin heavy variable 3-16 (non-functional)
chr14_-_106518922 13.38 ENST00000390598.2
immunoglobulin heavy variable 3-7
chr6_-_24877490 13.05 ENST00000540914.1
ENST00000378023.4
family with sequence similarity 65, member B
chr5_-_175964366 13.03 ENST00000274811.4
ring finger protein 44
chr1_+_152975488 13.00 ENST00000542696.1
small proline-rich protein 3
chr14_-_106725723 12.96 ENST00000390609.2
immunoglobulin heavy variable 3-23
chr17_+_14204389 12.90 ENST00000360954.2
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr2_-_99224915 12.77 ENST00000328709.3
ENST00000409997.1
cytochrome c oxidase assembly factor 5
chr1_+_104198377 12.75 ENST00000370083.4
amylase, alpha 1A (salivary)
chr4_-_46911223 12.74 ENST00000396533.1
cytochrome c oxidase subunit VIIb2
chr19_-_19144243 12.65 ENST00000594445.1
ENST00000452918.2
ENST00000600377.1
ENST00000337018.6
SURP and G patch domain containing 2
chr9_-_34691201 12.59 ENST00000378800.3
ENST00000311925.2
chemokine (C-C motif) ligand 19
chr1_+_192778161 12.56 ENST00000235382.5
regulator of G-protein signaling 2, 24kDa
chr4_-_46911248 12.50 ENST00000355591.3
ENST00000505102.1
cytochrome c oxidase subunit VIIb2
chr16_-_79634595 12.46 ENST00000326043.4
ENST00000393350.1
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr13_-_99910673 12.46 ENST00000397473.2
ENST00000397470.2
G protein-coupled receptor 18
chr17_-_41465674 12.44 ENST00000592135.1
ENST00000587874.1
ENST00000588654.1
ENST00000592094.1
long intergenic non-protein coding RNA 910
chr11_-_64511575 12.41 ENST00000431822.1
ENST00000377486.3
ENST00000394432.3
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr14_-_106967788 12.30 ENST00000390622.2
immunoglobulin heavy variable 1-46
chr6_-_52628271 12.16 ENST00000493422.1
glutathione S-transferase alpha 2
chr2_+_90259593 12.10 ENST00000471857.1
immunoglobulin kappa variable 1D-8
chr19_-_12267524 12.08 ENST00000455799.1
ENST00000355738.1
ENST00000439556.2
ENST00000542938.1
zinc finger protein 625
chr12_-_11422630 12.08 ENST00000381842.3
ENST00000538488.1
proline-rich protein BstNI subfamily 3
chr11_-_62369291 11.99 ENST00000278823.2
metastasis associated 1 family, member 2
chr1_+_32666188 11.88 ENST00000421922.2
coiled-coil domain containing 28B
chr5_+_66254698 11.86 ENST00000405643.1
ENST00000407621.1
ENST00000432426.1
microtubule associated serine/threonine kinase family member 4
chr22_-_43010928 11.83 ENST00000348657.2
ENST00000252115.5
polymerase (DNA-directed), delta interacting protein 3
chr11_-_2906979 11.80 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr2_+_68592305 11.76 ENST00000234313.7
pleckstrin

Network of associatons between targets according to the STRING database.

First level regulatory network of POU5F1_POU2F3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
23.7 71.2 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
17.9 2692.4 GO:0006958 complement activation, classical pathway(GO:0006958)
12.1 60.6 GO:0002399 MHC class II protein complex assembly(GO:0002399)
12.1 36.3 GO:0070668 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
10.4 124.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
9.3 27.8 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
7.0 21.1 GO:0019056 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
6.5 1120.7 GO:0002377 immunoglobulin production(GO:0002377)
5.2 20.8 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
4.8 14.3 GO:0061470 T follicular helper cell differentiation(GO:0061470)
4.8 23.9 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
4.2 12.6 GO:2000547 dendritic cell dendrite assembly(GO:0097026) regulation of dendritic cell dendrite assembly(GO:2000547)
4.0 8.0 GO:0002436 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264)
4.0 11.9 GO:0045925 positive regulation of female receptivity(GO:0045925)
3.9 31.4 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
3.8 15.4 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
3.7 14.6 GO:0043983 histone H4-K12 acetylation(GO:0043983)
3.6 14.3 GO:0036269 swimming behavior(GO:0036269)
3.6 7.1 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
3.6 17.8 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
3.5 14.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
3.5 20.9 GO:0018095 protein polyglutamylation(GO:0018095)
3.5 17.3 GO:0016476 regulation of embryonic cell shape(GO:0016476)
3.4 13.6 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
3.3 16.6 GO:1900920 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
3.3 13.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
3.3 9.8 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
3.2 42.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
3.2 6.4 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
3.1 6.1 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
3.1 9.2 GO:0072709 cellular response to sorbitol(GO:0072709)
2.7 8.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
2.7 18.9 GO:0033029 neutrophil apoptotic process(GO:0001781) regulation of neutrophil apoptotic process(GO:0033029)
2.7 5.4 GO:0010958 regulation of amino acid import(GO:0010958)
2.7 8.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
2.6 18.4 GO:0060294 cilium movement involved in cell motility(GO:0060294)
2.5 15.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
2.4 39.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
2.4 9.7 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
2.4 9.6 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
2.4 4.8 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
2.4 9.6 GO:0014807 regulation of somitogenesis(GO:0014807)
2.3 9.3 GO:0072423 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
2.3 6.9 GO:0045666 positive regulation of neuron differentiation(GO:0045666)
2.3 6.9 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
2.3 6.9 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
2.1 12.6 GO:0071877 regulation of adrenergic receptor signaling pathway(GO:0071877)
2.1 12.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
2.0 12.3 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
2.0 8.2 GO:0010165 response to X-ray(GO:0010165)
2.0 28.5 GO:0002544 chronic inflammatory response(GO:0002544)
2.0 16.3 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
2.0 4.1 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
2.0 46.0 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
2.0 16.0 GO:0009615 response to virus(GO:0009615)
2.0 5.9 GO:0021571 rhombomere 3 development(GO:0021569) rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
2.0 11.8 GO:0033625 positive regulation of integrin activation(GO:0033625) protein secretion by platelet(GO:0070560)
1.9 13.6 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
1.9 7.7 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
1.9 5.8 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
1.9 7.7 GO:0003219 cardiac right ventricle formation(GO:0003219)
1.8 12.9 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
1.8 9.2 GO:0030070 insulin processing(GO:0030070)
1.8 5.5 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
1.8 1.8 GO:0060067 cervix development(GO:0060067)
1.8 33.6 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
1.7 18.2 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
1.6 13.0 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
1.6 4.9 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
1.6 6.4 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
1.6 4.8 GO:0097254 renal tubular secretion(GO:0097254)
1.6 7.9 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
1.6 3.2 GO:0008050 female courtship behavior(GO:0008050)
1.6 9.3 GO:0001714 endodermal cell fate specification(GO:0001714)
1.5 7.7 GO:0070842 aggresome assembly(GO:0070842)
1.5 56.3 GO:0007257 activation of JUN kinase activity(GO:0007257)
1.5 10.6 GO:0032596 protein transport within lipid bilayer(GO:0032594) protein transport into membrane raft(GO:0032596)
1.5 1.5 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
1.5 13.3 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.5 10.3 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
1.5 8.8 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
1.4 5.8 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
1.4 4.3 GO:0048852 hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852)
1.4 5.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.4 5.5 GO:0035701 hematopoietic stem cell migration(GO:0035701)
1.3 2.7 GO:2000366 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
1.3 6.6 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
1.3 15.8 GO:0048251 elastic fiber assembly(GO:0048251)
1.3 6.6 GO:1903960 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960)
1.3 10.4 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
1.3 64.9 GO:0018149 peptide cross-linking(GO:0018149)
1.3 3.8 GO:0060595 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
1.3 5.1 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
1.3 3.8 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
1.2 8.6 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
1.2 11.9 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
1.2 3.5 GO:0010430 fatty acid omega-oxidation(GO:0010430)
1.2 20.8 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
1.1 3.4 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
1.1 13.1 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
1.1 8.6 GO:0070995 NADPH oxidation(GO:0070995)
1.1 6.4 GO:0035799 ureter maturation(GO:0035799)
1.1 5.3 GO:0016045 detection of bacterium(GO:0016045)
1.0 4.1 GO:0036343 psychomotor behavior(GO:0036343)
1.0 7.2 GO:0043654 recognition of apoptotic cell(GO:0043654)
1.0 9.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
1.0 3.0 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
1.0 4.9 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
1.0 5.9 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
1.0 3.9 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
1.0 2.9 GO:0061386 closure of optic fissure(GO:0061386)
1.0 3.8 GO:0030223 neutrophil differentiation(GO:0030223)
0.9 2.8 GO:0006014 D-ribose metabolic process(GO:0006014)
0.9 6.6 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.9 3.7 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.9 2.8 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.9 10.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.9 54.6 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.9 5.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.9 5.3 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.9 7.0 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.9 5.2 GO:0006196 AMP catabolic process(GO:0006196)
0.9 8.6 GO:0001865 NK T cell differentiation(GO:0001865)
0.9 8.6 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.9 3.4 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.9 10.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.9 5.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.8 0.8 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.8 6.6 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.8 6.5 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.8 34.2 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.8 2.4 GO:0009447 putrescine catabolic process(GO:0009447)
0.8 3.8 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.8 4.5 GO:1901096 regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.7 11.5 GO:0031033 myosin filament organization(GO:0031033)
0.7 6.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.7 7.8 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.7 8.5 GO:0036158 outer dynein arm assembly(GO:0036158)
0.7 7.5 GO:0006554 lysine catabolic process(GO:0006554)
0.7 3.4 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.7 9.9 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.7 5.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.6 2.6 GO:0000023 maltose metabolic process(GO:0000023)
0.6 3.2 GO:0090131 mesenchyme migration(GO:0090131)
0.6 4.4 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.6 2.5 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.6 1.9 GO:0015871 choline transport(GO:0015871)
0.6 1.9 GO:1903027 regulation of opsonization(GO:1903027)
0.6 11.8 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.6 6.8 GO:0048263 determination of dorsal identity(GO:0048263)
0.6 9.8 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.6 6.7 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.6 4.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.6 57.6 GO:0030183 B cell differentiation(GO:0030183)
0.6 4.7 GO:0003190 atrioventricular valve formation(GO:0003190)
0.6 5.8 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.6 2.9 GO:0021759 globus pallidus development(GO:0021759)
0.6 2.9 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.6 4.6 GO:0006689 ganglioside catabolic process(GO:0006689)
0.6 6.8 GO:0044146 negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.6 4.5 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.6 7.2 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.6 3.3 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.6 5.0 GO:0008343 adult feeding behavior(GO:0008343)
0.5 2.7 GO:0006067 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.5 2.2 GO:1900827 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.5 12.9 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.5 2.1 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.5 1.6 GO:0060168 regulation of adenosine receptor signaling pathway(GO:0060167) positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.5 3.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.5 5.6 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.5 4.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.5 9.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.5 2.0 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.5 16.9 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.5 11.8 GO:0035455 response to interferon-alpha(GO:0035455)
0.5 9.8 GO:0036035 osteoclast development(GO:0036035)
0.5 8.7 GO:0051607 defense response to virus(GO:0051607)
0.5 3.9 GO:0007258 JUN phosphorylation(GO:0007258)
0.5 1.4 GO:2000870 positive regulation of female gonad development(GO:2000196) regulation of progesterone secretion(GO:2000870)
0.5 2.8 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.5 2.3 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.5 1.9 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.5 1.4 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.5 4.6 GO:0046834 lipid phosphorylation(GO:0046834)
0.5 5.5 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.5 1.8 GO:0015942 folic acid-containing compound catabolic process(GO:0009397) formate metabolic process(GO:0015942) pteridine-containing compound catabolic process(GO:0042560)
0.4 2.2 GO:0030035 microspike assembly(GO:0030035)
0.4 8.2 GO:0021542 dentate gyrus development(GO:0021542)
0.4 1.3 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.4 1.7 GO:0097368 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.4 3.0 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.4 9.6 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.4 6.7 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.4 8.3 GO:2000811 negative regulation of anoikis(GO:2000811)
0.4 4.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.4 11.2 GO:0050832 defense response to fungus(GO:0050832)
0.4 1.6 GO:0042220 response to cocaine(GO:0042220)
0.4 8.7 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.4 3.9 GO:0072672 neutrophil extravasation(GO:0072672)
0.4 27.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.4 1.2 GO:0048539 bone marrow development(GO:0048539)
0.4 1.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.4 11.7 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.4 1.1 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.4 4.8 GO:0005513 detection of calcium ion(GO:0005513)
0.4 15.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.4 6.9 GO:0046135 pyrimidine nucleoside catabolic process(GO:0046135)
0.4 2.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.4 3.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.4 6.4 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.4 2.1 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.3 1.4 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.3 4.8 GO:0021516 dorsal spinal cord development(GO:0021516)
0.3 2.4 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.3 1.7 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.3 2.9 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.3 8.4 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.3 1.0 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.3 4.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.3 2.2 GO:0034765 regulation of ion transmembrane transport(GO:0034765)
0.3 2.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.3 12.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.3 3.7 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.3 4.0 GO:0098751 bone cell development(GO:0098751)
0.3 9.1 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.3 10.9 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.3 2.0 GO:0006572 tyrosine catabolic process(GO:0006572)
0.3 74.4 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.3 15.4 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.3 3.6 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.3 2.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.3 16.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.3 3.5 GO:0017121 phospholipid scrambling(GO:0017121)
0.3 10.8 GO:0033344 cholesterol efflux(GO:0033344)
0.3 4.9 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.3 2.7 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.3 1.9 GO:0046485 ether lipid metabolic process(GO:0046485)
0.3 3.5 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.3 5.5 GO:0030225 macrophage differentiation(GO:0030225)
0.3 8.4 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.3 1.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.3 3.6 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.3 1.8 GO:0015870 acetylcholine transport(GO:0015870)
0.3 3.3 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.3 5.1 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.3 2.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.3 5.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.3 1.3 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.2 1.2 GO:0032364 oxygen homeostasis(GO:0032364)
0.2 1.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.2 5.0 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.2 8.6 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.2 1.6 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.2 1.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.2 8.2 GO:0019228 neuronal action potential(GO:0019228)
0.2 2.0 GO:0015939 pantothenate metabolic process(GO:0015939)
0.2 0.7 GO:0006114 glycerol biosynthetic process(GO:0006114) response to methionine(GO:1904640)
0.2 1.5 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.2 2.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.2 4.2 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.2 4.2 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.2 30.8 GO:0006906 vesicle fusion(GO:0006906)
0.2 1.6 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2 4.6 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.2 14.0 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.2 2.5 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.2 3.0 GO:0001709 cell fate determination(GO:0001709)
0.2 3.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.2 35.5 GO:0002250 adaptive immune response(GO:0002250)
0.2 0.6 GO:2000342 negative regulation of interleukin-8 biosynthetic process(GO:0045415) negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.2 6.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.2 2.0 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.2 8.1 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.2 2.2 GO:0042306 regulation of protein import into nucleus(GO:0042306) regulation of protein import(GO:1904589)
0.2 7.7 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.2 3.9 GO:0045576 mast cell activation(GO:0045576)
0.2 6.8 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.2 1.5 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.2 3.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.2 1.9 GO:0060037 pharyngeal system development(GO:0060037)
0.2 0.3 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 4.5 GO:0042417 dopamine metabolic process(GO:0042417)
0.1 0.6 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 2.3 GO:0019722 calcium-mediated signaling(GO:0019722)
0.1 3.4 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 1.0 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.1 1.7 GO:0090312 positive regulation of protein deacetylation(GO:0090312)
0.1 0.7 GO:0048665 neuron fate specification(GO:0048665)
0.1 5.1 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.1 0.4 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 1.2 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 3.6 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 3.4 GO:0007409 axonogenesis(GO:0007409)
0.1 6.0 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 3.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 8.0 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 1.2 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 4.5 GO:0060976 coronary vasculature development(GO:0060976)
0.1 0.7 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 8.7 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 1.2 GO:0001756 somitogenesis(GO:0001756)
0.1 2.1 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 2.5 GO:0033198 response to ATP(GO:0033198)
0.1 1.6 GO:0050860 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 2.7 GO:0014047 glutamate secretion(GO:0014047)
0.1 0.4 GO:0009629 response to gravity(GO:0009629)
0.1 0.5 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 3.2 GO:0010107 potassium ion import(GO:0010107)
0.1 0.9 GO:0006702 androgen biosynthetic process(GO:0006702)
0.1 3.1 GO:0060711 labyrinthine layer development(GO:0060711)
0.1 1.0 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 6.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 2.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 6.3 GO:0007631 feeding behavior(GO:0007631)
0.1 1.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 10.7 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.1 7.8 GO:0034332 adherens junction organization(GO:0034332)
0.1 0.5 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 1.8 GO:0044253 positive regulation of collagen metabolic process(GO:0010714) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.1 1.0 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 4.0 GO:0006968 cellular defense response(GO:0006968)
0.1 0.9 GO:0021549 cerebellum development(GO:0021549) metencephalon development(GO:0022037)
0.1 2.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 2.0 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.5 GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 1.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 1.0 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 1.9 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 1.4 GO:0003407 neural retina development(GO:0003407)
0.0 0.4 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 1.4 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 5.2 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 1.2 GO:0003091 renal water homeostasis(GO:0003091)
0.0 0.4 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.5 GO:0021591 ventricular system development(GO:0021591)
0.0 0.1 GO:0086097 renin-angiotensin regulation of aldosterone production(GO:0002018) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873) phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.5 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 1.2 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 1.1 GO:0017156 calcium ion regulated exocytosis(GO:0017156)
0.0 1.0 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.1 GO:0014874 response to muscle inactivity(GO:0014870) response to stimulus involved in regulation of muscle adaptation(GO:0014874) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 1.8 GO:0070268 cornification(GO:0070268)
0.0 0.2 GO:0002507 tolerance induction(GO:0002507)
0.0 0.8 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.2 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.0 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.6 GO:0038034 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 0.0 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.7 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
19.8 59.4 GO:0071745 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
16.8 790.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
8.9 124.6 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
7.3 36.3 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
7.1 49.9 GO:0019815 B cell receptor complex(GO:0019815)
4.2 88.4 GO:0042613 MHC class II protein complex(GO:0042613)
3.5 14.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
3.4 13.6 GO:0031088 platelet dense granule membrane(GO:0031088)
3.2 16.1 GO:0098843 postsynaptic endocytic zone(GO:0098843)
2.9 529.1 GO:0072562 blood microparticle(GO:0072562)
2.9 34.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
2.5 17.8 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
2.3 9.3 GO:0043293 apoptosome(GO:0043293)
2.3 11.6 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
2.3 6.9 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
2.2 11.1 GO:0005579 membrane attack complex(GO:0005579)
2.2 8.8 GO:0030485 smooth muscle contractile fiber(GO:0030485)
2.1 8.6 GO:1990031 pinceau fiber(GO:1990031)
1.8 9.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.8 15.8 GO:0071953 elastic fiber(GO:0071953)
1.7 17.3 GO:0070938 contractile ring(GO:0070938)
1.6 9.8 GO:0005577 fibrinogen complex(GO:0005577)
1.6 27.2 GO:0045277 respiratory chain complex IV(GO:0045277)
1.4 7.0 GO:0044308 axonal spine(GO:0044308)
1.4 9.7 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
1.3 8.1 GO:0032009 early phagosome(GO:0032009)
1.3 4.0 GO:0036398 TCR signalosome(GO:0036398)
1.2 6.2 GO:0045298 tubulin complex(GO:0045298)
1.2 65.0 GO:0001533 cornified envelope(GO:0001533)
1.2 7.3 GO:0000322 storage vacuole(GO:0000322)
1.2 3.6 GO:0032437 cuticular plate(GO:0032437)
1.1 8.5 GO:0036157 outer dynein arm(GO:0036157)
1.0 5.2 GO:0071546 pi-body(GO:0071546)
0.9 1451.5 GO:0005615 extracellular space(GO:0005615)
0.8 77.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.8 5.0 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.8 9.8 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.8 11.8 GO:0000346 transcription export complex(GO:0000346)
0.8 2.3 GO:0097447 dendritic tree(GO:0097447)
0.8 10.8 GO:0031083 BLOC-1 complex(GO:0031083)
0.7 2.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.7 5.5 GO:0035976 AP1 complex(GO:0035976)
0.7 2.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.7 39.0 GO:0035577 azurophil granule membrane(GO:0035577)
0.6 22.9 GO:0016592 mediator complex(GO:0016592)
0.6 3.0 GO:0089701 U2AF(GO:0089701)
0.6 3.5 GO:0097524 sperm plasma membrane(GO:0097524)
0.6 8.0 GO:0005687 U4 snRNP(GO:0005687)
0.6 9.1 GO:0097512 cardiac myofibril(GO:0097512)
0.6 3.4 GO:1990037 Lewy body core(GO:1990037)
0.6 7.8 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.5 15.6 GO:0001726 ruffle(GO:0001726)
0.5 2.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.5 30.5 GO:0030427 site of polarized growth(GO:0030427)
0.5 8.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.5 9.1 GO:0044295 axonal growth cone(GO:0044295)
0.5 23.5 GO:0048786 presynaptic active zone(GO:0048786)
0.5 5.9 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.4 35.1 GO:0036064 ciliary basal body(GO:0036064)
0.4 23.4 GO:0031901 early endosome membrane(GO:0031901)
0.4 6.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.4 11.1 GO:0034451 centriolar satellite(GO:0034451)
0.4 11.2 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.4 13.0 GO:1902711 GABA-A receptor complex(GO:1902711)
0.3 5.1 GO:0046930 pore complex(GO:0046930)
0.3 1.9 GO:0002116 semaphorin receptor complex(GO:0002116)
0.3 11.2 GO:0005859 muscle myosin complex(GO:0005859)
0.3 38.7 GO:0016605 PML body(GO:0016605)
0.3 22.9 GO:0042734 presynaptic membrane(GO:0042734)
0.3 6.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.3 4.5 GO:0036020 endolysosome membrane(GO:0036020)
0.3 11.6 GO:0008305 integrin complex(GO:0008305)
0.3 2.4 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.3 14.2 GO:0005796 Golgi lumen(GO:0005796)
0.3 3.3 GO:0030673 axolemma(GO:0030673)
0.3 6.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.3 14.2 GO:0043195 terminal bouton(GO:0043195)
0.3 6.5 GO:0042629 mast cell granule(GO:0042629)
0.3 3.3 GO:0000815 ESCRT III complex(GO:0000815)
0.3 2.3 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.3 16.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.2 2.7 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 48.1 GO:0032993 protein-DNA complex(GO:0032993)
0.2 0.5 GO:0005916 fascia adherens(GO:0005916)
0.2 9.4 GO:0016235 aggresome(GO:0016235)
0.2 6.4 GO:1904115 axon cytoplasm(GO:1904115)
0.2 3.6 GO:0031932 TORC2 complex(GO:0031932)
0.2 1.9 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 6.1 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.2 5.4 GO:0035580 specific granule lumen(GO:0035580)
0.2 2.2 GO:0043194 axon initial segment(GO:0043194)
0.2 1.4 GO:0042382 paraspeckles(GO:0042382)
0.2 4.6 GO:0031904 endosome lumen(GO:0031904)
0.2 1.2 GO:0097361 CIA complex(GO:0097361)
0.2 1.6 GO:0016013 syntrophin complex(GO:0016013)
0.2 17.0 GO:0031225 anchored component of membrane(GO:0031225)
0.2 4.5 GO:0043204 perikaryon(GO:0043204)
0.2 7.7 GO:0005902 microvillus(GO:0005902)
0.1 4.3 GO:0000791 euchromatin(GO:0000791)
0.1 1.0 GO:0000813 ESCRT I complex(GO:0000813)
0.1 614.5 GO:0005886 plasma membrane(GO:0005886)
0.1 14.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 2.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 1.7 GO:0002102 podosome(GO:0002102)
0.1 3.2 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.8 GO:0016459 myosin complex(GO:0016459)
0.0 0.8 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 0.9 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 3.0 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 4.6 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 1.8 GO:0001650 fibrillar center(GO:0001650)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
23.7 71.2 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
18.5 55.4 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
15.6 3668.9 GO:0003823 antigen binding(GO:0003823)
13.0 39.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
10.4 135.0 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
9.5 28.5 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
4.9 34.4 GO:0043208 glycosphingolipid binding(GO:0043208)
4.2 80.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
3.8 15.3 GO:0016160 amylase activity(GO:0016160)
3.5 20.7 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
3.1 15.7 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
3.1 12.6 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
2.9 8.8 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
2.9 17.3 GO:0043237 laminin-1 binding(GO:0043237)
2.7 48.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
2.7 8.0 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
2.4 9.6 GO:0004657 proline dehydrogenase activity(GO:0004657)
2.3 18.3 GO:0070324 thyroid hormone binding(GO:0070324)
2.2 6.5 GO:0097100 supercoiled DNA binding(GO:0097100)
2.1 12.5 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
2.1 20.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
2.0 14.3 GO:0008142 oxysterol binding(GO:0008142)
2.0 8.2 GO:0042954 apolipoprotein receptor activity(GO:0030226) lipoprotein transporter activity(GO:0042954)
2.0 6.1 GO:0017129 triglyceride binding(GO:0017129)
2.0 17.9 GO:0043426 MRF binding(GO:0043426)
2.0 5.9 GO:0004157 dihydropyrimidinase activity(GO:0004157)
2.0 9.8 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
1.9 23.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
1.9 7.7 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
1.9 29.8 GO:0042809 vitamin D receptor binding(GO:0042809)
1.8 124.6 GO:0050840 extracellular matrix binding(GO:0050840)
1.8 7.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
1.8 5.5 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
1.7 6.8 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
1.7 9.9 GO:0004522 ribonuclease A activity(GO:0004522)
1.6 19.5 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
1.6 21.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004) neurotrophin receptor activity(GO:0005030)
1.6 4.8 GO:0030158 protein xylosyltransferase activity(GO:0030158)
1.5 6.2 GO:0099609 microtubule lateral binding(GO:0099609)
1.5 20.8 GO:0035325 Toll-like receptor binding(GO:0035325)
1.5 10.4 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
1.4 7.1 GO:0046625 sphingolipid binding(GO:0046625)
1.4 14.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
1.3 9.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
1.3 18.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
1.3 7.8 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
1.3 3.9 GO:0032427 GBD domain binding(GO:0032427)
1.2 22.3 GO:0019992 diacylglycerol binding(GO:0019992)
1.2 4.9 GO:1990430 extracellular matrix protein binding(GO:1990430)
1.2 19.2 GO:0097109 neuroligin family protein binding(GO:0097109)
1.2 13.1 GO:0051525 NFAT protein binding(GO:0051525)
1.2 10.6 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
1.1 4.6 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
1.1 5.6 GO:0070097 delta-catenin binding(GO:0070097)
1.1 4.4 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
1.1 3.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
1.1 4.3 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
1.1 5.3 GO:0004925 prolactin receptor activity(GO:0004925)
1.1 4.2 GO:0047708 biotinidase activity(GO:0047708)
1.0 6.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
1.0 7.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.0 2.0 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.9 14.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.9 27.2 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.9 6.9 GO:0070412 R-SMAD binding(GO:0070412)
0.8 2.5 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.8 5.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.8 4.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.8 4.9 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.8 5.6 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.8 10.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.7 2.9 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.7 2.1 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.7 11.8 GO:0005522 profilin binding(GO:0005522)
0.7 2.0 GO:1904288 BAT3 complex binding(GO:1904288)
0.7 11.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.7 7.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.6 13.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.6 7.7 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.6 3.9 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.6 8.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.6 10.5 GO:0038191 neuropilin binding(GO:0038191)
0.6 3.7 GO:0003998 acylphosphatase activity(GO:0003998)
0.6 1.8 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.6 3.0 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.6 6.0 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.6 5.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.6 6.3 GO:0005504 fatty acid binding(GO:0005504)
0.6 4.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.6 3.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.5 3.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.5 5.9 GO:0071837 HMG box domain binding(GO:0071837)
0.5 5.6 GO:0050811 GABA receptor binding(GO:0050811)
0.5 16.2 GO:0001671 ATPase activator activity(GO:0001671)
0.5 2.0 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.5 1.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.5 1.5 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.5 11.8 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.5 2.9 GO:0003796 lysozyme activity(GO:0003796)
0.5 4.8 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.5 5.3 GO:0042834 peptidoglycan binding(GO:0042834)
0.5 1.9 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.5 9.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.5 5.1 GO:0051434 BH3 domain binding(GO:0051434)
0.5 4.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.4 1.8 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.4 6.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.4 6.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.4 6.4 GO:0016918 retinal binding(GO:0016918)
0.4 7.7 GO:0070628 proteasome binding(GO:0070628)
0.4 7.6 GO:0050786 RAGE receptor binding(GO:0050786)
0.4 0.8 GO:0022840 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.4 5.9 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.4 2.0 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.4 12.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.4 13.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.4 8.8 GO:0070403 NAD+ binding(GO:0070403)
0.4 1.6 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.4 2.7 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.4 3.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.4 3.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.4 6.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.4 1.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.4 4.9 GO:0031432 titin binding(GO:0031432)
0.4 8.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.4 2.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.4 13.0 GO:0004890 GABA-A receptor activity(GO:0004890)
0.4 2.9 GO:0030215