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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for RFX7_RFX4_RFX1

Z-value: 2.05

Motif logo

Transcription factors associated with RFX7_RFX4_RFX1

Gene Symbol Gene ID Gene Info
ENSG00000181827.10 regulatory factor X7
ENSG00000111783.8 regulatory factor X4
ENSG00000132005.4 regulatory factor X1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RFX1hg19_v2_chr19_-_14117074_141171410.351.0e-07Click!
RFX7hg19_v2_chr15_-_56535464_565355210.252.3e-04Click!

Activity profile of RFX7_RFX4_RFX1 motif

Sorted Z-values of RFX7_RFX4_RFX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_50316517 76.32 ENST00000313777.4
ENST00000445575.2
fuzzy planar cell polarity protein
chr19_-_50316489 67.38 ENST00000533418.1
fuzzy planar cell polarity protein
chr19_-_50316423 59.49 ENST00000528094.1
ENST00000526575.1
fuzzy planar cell polarity protein
chr11_+_71791693 55.59 ENST00000289488.2
ENST00000447974.1
leucine rich transmembrane and O-methyltransferase domain containing
chr3_-_128712955 50.55 ENST00000265068.5
KIAA1257
chr8_+_10530155 44.23 ENST00000521818.1
chromosome 8 open reading frame 74
chr17_-_15244894 43.43 ENST00000338696.2
ENST00000543896.1
ENST00000539245.1
ENST00000539316.1
ENST00000395930.1
tektin 3
chr19_-_46974741 40.44 ENST00000313683.10
ENST00000602246.1
paraneoplastic Ma antigen family-like 1
chr19_-_46974664 38.67 ENST00000438932.2
paraneoplastic Ma antigen family-like 1
chr19_+_2096868 37.96 ENST00000395296.1
ENST00000395301.3
IZUMO family member 4
chr1_-_15735925 33.51 ENST00000427824.1
RP3-467K16.4
chr2_-_196933536 33.30 ENST00000312428.6
ENST00000410072.1
dynein, axonemal, heavy chain 7
chr4_+_176986978 33.25 ENST00000508596.1
ENST00000393643.2
WD repeat domain 17
chr17_+_17876127 33.08 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
leucine rich repeat containing 48
chr6_-_159420780 32.99 ENST00000449822.1
radial spoke 3 homolog (Chlamydomonas)
chr1_+_1981890 32.66 ENST00000378567.3
ENST00000468310.1
protein kinase C, zeta
chr2_-_220110111 31.97 ENST00000428427.1
ENST00000356283.3
ENST00000432839.1
ENST00000424620.1
galactosidase, beta 1-like
chr8_+_144816303 31.86 ENST00000533004.1
FAM83H antisense RNA 1 (head to head)
chr2_-_220110187 29.33 ENST00000295759.7
ENST00000392089.2
galactosidase, beta 1-like
chr3_+_111718173 28.40 ENST00000494932.1
transgelin 3
chr8_-_27115931 28.18 ENST00000523048.1
stathmin-like 4
chr19_+_48972459 27.98 ENST00000427476.1
cytohesin 2
chr2_-_63815628 27.95 ENST00000409562.3
WD repeat containing planar cell polarity effector
chr1_-_11865982 27.86 ENST00000418034.1
methylenetetrahydrofolate reductase (NAD(P)H)
chr7_-_129845313 27.62 ENST00000397622.2
transmembrane protein 209
chr6_-_159421198 27.39 ENST00000252655.1
ENST00000297262.3
ENST00000367069.2
radial spoke 3 homolog (Chlamydomonas)
chr20_+_49575342 26.80 ENST00000244051.1
molybdenum cofactor synthesis 3
chr11_-_116968987 26.27 ENST00000434315.2
ENST00000292055.4
ENST00000375288.1
ENST00000542607.1
ENST00000445177.1
ENST00000375300.1
ENST00000446921.2
SIK family kinase 3
chr1_+_11866207 25.07 ENST00000312413.6
ENST00000346436.6
chloride channel, voltage-sensitive 6
chr1_+_11866270 24.73 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
chloride channel, voltage-sensitive 6
chr6_+_163148973 24.72 ENST00000366888.2
PARK2 co-regulated
chr6_+_142468361 24.65 ENST00000367630.4
vesicle (multivesicular body) trafficking 1
chr8_-_27115903 24.30 ENST00000350889.4
ENST00000519997.1
ENST00000519614.1
ENST00000522908.1
ENST00000265770.7
stathmin-like 4
chr7_-_129845188 24.02 ENST00000462753.1
ENST00000471077.1
ENST00000473456.1
ENST00000336804.8
transmembrane protein 209
chr9_+_79792410 23.90 ENST00000357409.5
vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr1_+_36549676 23.29 ENST00000207457.3
tektin 2 (testicular)
chr4_-_153457197 22.44 ENST00000281708.4
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr2_-_62081254 22.19 ENST00000405894.3
family with sequence similarity 161, member A
chr19_-_46296011 22.08 ENST00000377735.3
ENST00000270223.6
dystrophia myotonica, WD repeat containing
chr2_+_61293021 21.32 ENST00000402291.1
KIAA1841
chr1_-_11866034 20.93 ENST00000376590.3
methylenetetrahydrofolate reductase (NAD(P)H)
chr6_-_163148780 20.86 ENST00000366892.1
ENST00000366898.1
ENST00000366897.1
ENST00000366896.1
parkin RBR E3 ubiquitin protein ligase
chr7_+_156902674 20.62 ENST00000594086.1
Protein LOC100996426
chr22_+_38453378 20.44 ENST00000437453.1
ENST00000356976.3
protein interacting with PRKCA 1
chr17_+_16284104 20.11 ENST00000577958.1
ENST00000302182.3
ENST00000577640.1
ubiquitin B
chr13_-_30881621 19.90 ENST00000380615.3
katanin p60 subunit A-like 1
chr1_+_207226574 19.83 ENST00000367080.3
ENST00000367079.2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr5_-_137475071 19.77 ENST00000265191.2
NME/NM23 family member 5
chr2_-_62081148 19.75 ENST00000404929.1
family with sequence similarity 161, member A
chr6_+_111580508 19.67 ENST00000368847.4
KIAA1919
chr22_+_38453207 19.01 ENST00000404072.3
ENST00000424694.1
protein interacting with PRKCA 1
chr1_-_207226313 18.60 ENST00000367084.1
YOD1 deubiquitinase
chr19_+_5681011 18.53 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
hydroxysteroid (11-beta) dehydrogenase 1-like
chr19_+_10217364 18.51 ENST00000430370.1
peter pan homolog (Drosophila)
chr3_+_111718036 18.36 ENST00000455401.2
transgelin 3
chr11_-_6426635 18.24 ENST00000608645.1
ENST00000608394.1
ENST00000529519.1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr19_-_40324767 17.45 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr2_+_84743562 17.38 ENST00000389394.3
ENST00000398278.2
dynein, axonemal, heavy chain 6
chr15_-_64648273 17.17 ENST00000607537.1
ENST00000303052.7
ENST00000303032.6
casein kinase 1, gamma 1
chr20_-_18447667 17.08 ENST00000262547.5
ENST00000329494.5
ENST00000357236.4
double zinc ribbon and ankyrin repeat domains 1
chr8_+_42010464 17.06 ENST00000518421.1
ENST00000174653.3
ENST00000396926.3
ENST00000521280.1
ENST00000522288.1
adaptor-related protein complex 3, mu 2 subunit
chr13_+_21141208 16.90 ENST00000351808.5
intraflagellar transport 88 homolog (Chlamydomonas)
chr17_-_42992856 16.88 ENST00000588316.1
ENST00000435360.2
ENST00000586793.1
ENST00000588735.1
ENST00000588037.1
ENST00000592320.1
ENST00000253408.5
glial fibrillary acidic protein
chr13_+_42846272 16.79 ENST00000025301.2
A kinase (PRKA) anchor protein 11
chr1_-_235814048 16.62 ENST00000450593.1
ENST00000366598.4
guanine nucleotide binding protein (G protein), gamma 4
chr19_-_39390440 16.52 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
sirtuin 2
chr14_+_74111578 16.21 ENST00000554113.1
ENST00000555631.2
ENST00000553645.2
ENST00000311089.3
ENST00000555919.3
ENST00000554339.1
ENST00000554871.1
dynein, axonemal, light chain 1
chr12_+_107168342 16.13 ENST00000392837.4
RIC8 guanine nucleotide exchange factor B
chr17_+_48585794 16.12 ENST00000576179.1
ENST00000419930.1
MYCBP associated protein
chr1_+_206809113 15.86 ENST00000441486.1
ENST00000367106.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr17_+_72270429 15.80 ENST00000311014.6
dynein, axonemal, intermediate chain 2
chr9_-_116102530 15.73 ENST00000374195.3
ENST00000341761.4
WD repeat domain 31
chr9_+_135545409 15.72 ENST00000483873.2
ENST00000372146.4
general transcription factor IIIC, polypeptide 4, 90kDa
chr11_+_113185292 15.70 ENST00000429951.1
ENST00000442859.1
ENST00000531164.1
ENST00000529850.1
ENST00000314756.3
ENST00000525965.1
tetratricopeptide repeat domain 12
chr17_+_48585958 15.64 ENST00000436259.2
MYCBP associated protein
chr8_-_98290087 15.54 ENST00000322128.3
TSPY-like 5
chr2_+_29204161 15.40 ENST00000379558.4
ENST00000403861.2
family with sequence similarity 179, member A
chr1_+_46972668 15.34 ENST00000371956.4
ENST00000360032.3
diencephalon/mesencephalon homeobox 1
chr13_+_21141270 15.20 ENST00000319980.6
ENST00000537103.1
ENST00000389373.3
intraflagellar transport 88 homolog (Chlamydomonas)
chrX_-_13835147 14.78 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chr19_-_39390350 14.75 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
sirtuin 2
chr19_-_40324255 14.67 ENST00000593685.1
ENST00000600611.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr11_-_64885111 14.60 ENST00000528598.1
ENST00000310597.4
zinc finger, HIT-type containing 2
chr12_+_107168418 14.58 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
RIC8 guanine nucleotide exchange factor B
chr19_-_58609570 14.17 ENST00000600845.1
ENST00000240727.6
ENST00000600897.1
ENST00000421612.2
ENST00000601063.1
ENST00000601144.1
zinc finger and SCAN domain containing 18
chr14_+_105452094 14.09 ENST00000551606.1
ENST00000547315.1
chromosome 14 open reading frame 79
chr16_+_90089008 14.04 ENST00000268699.4
growth arrest-specific 8
chr16_-_72127550 13.96 ENST00000268483.3
thioredoxin-like 4B
chr14_-_22005062 13.53 ENST00000317492.5
spalt-like transcription factor 2
chr1_-_85155939 13.48 ENST00000603677.1
synovial sarcoma, X breakpoint 2 interacting protein
chr22_-_23484246 13.36 ENST00000216036.4
rhabdoid tumor deletion region gene 1
chr19_+_10217270 13.32 ENST00000446223.1
peter pan homolog (Drosophila)
chrX_+_38420623 13.24 ENST00000378482.2
tetraspanin 7
chr16_+_19729586 13.20 ENST00000564186.1
ENST00000541926.1
ENST00000433597.2
IQ motif containing K
chr2_-_175869936 13.13 ENST00000409900.3
chimerin 1
chr20_+_814377 12.92 ENST00000304189.2
ENST00000381939.1
family with sequence similarity 110, member A
chr12_+_49687425 12.91 ENST00000257860.4
peripherin
chr4_+_128554081 12.86 ENST00000335251.6
ENST00000296461.5
inturned planar cell polarity protein
chr19_+_58111241 12.86 ENST00000597700.1
ENST00000332854.6
ENST00000597864.1
zinc finger protein 530
chr15_+_90777424 12.83 ENST00000561433.1
ENST00000559204.1
ENST00000558291.1
GDP-D-glucose phosphorylase 1
chr1_-_21044489 12.68 ENST00000247986.2
kinesin family member 17
chr1_+_206808868 12.63 ENST00000367109.2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr4_+_106631966 12.52 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
glutathione S-transferase, C-terminal domain containing
chr17_-_17875688 12.11 ENST00000379504.3
ENST00000318094.10
ENST00000540946.1
ENST00000542206.1
ENST00000395739.4
ENST00000581396.1
ENST00000535933.1
ENST00000579586.1
target of myb1-like 2 (chicken)
chr17_+_72270380 11.97 ENST00000582036.1
ENST00000307504.5
dynein, axonemal, intermediate chain 2
chr1_+_206808918 11.88 ENST00000367108.3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr8_+_15397732 11.86 ENST00000382020.4
ENST00000506802.1
ENST00000509380.1
ENST00000503731.1
tumor suppressor candidate 3
chr14_+_75536335 11.85 ENST00000554763.1
ENST00000439583.2
ENST00000526130.1
ENST00000525046.1
zinc finger, C2HC-type containing 1C
chr14_+_75536280 11.83 ENST00000238686.8
zinc finger, C2HC-type containing 1C
chr11_+_113185533 11.83 ENST00000393020.1
tetratricopeptide repeat domain 12
chr3_+_111717600 11.82 ENST00000273368.4
transgelin 3
chr19_-_3801789 11.73 ENST00000590849.1
ENST00000395045.2
megakaryocyte-associated tyrosine kinase
chr22_+_23487513 11.69 ENST00000263116.2
ENST00000341989.4
RAB36, member RAS oncogene family
chr22_+_45809560 11.65 ENST00000342894.3
ENST00000538017.1
RIB43A domain with coiled-coils 2
chr1_-_86861936 11.60 ENST00000394733.2
ENST00000359242.3
ENST00000294678.2
ENST00000479890.1
ENST00000317336.7
ENST00000370567.1
ENST00000394731.1
ENST00000478286.2
ENST00000370566.3
outer dense fiber of sperm tails 2-like
chr7_+_158649242 11.50 ENST00000407559.3
WD repeat domain 60
chr15_+_71184931 11.46 ENST00000560369.1
ENST00000260382.5
leucine rich repeat containing 49
chr15_+_101142722 11.40 ENST00000332783.7
ENST00000558747.1
ENST00000343276.4
ankyrin repeat and SOCS box containing 7
chr3_+_111717511 11.33 ENST00000478951.1
ENST00000393917.2
transgelin 3
chr12_+_111051832 11.29 ENST00000550703.2
ENST00000551590.1
tectonic family member 1
chr5_+_68389807 11.27 ENST00000380860.4
ENST00000504103.1
ENST00000502979.1
solute carrier family 30 (zinc transporter), member 5
chr12_+_111051902 11.14 ENST00000397655.3
ENST00000471804.2
ENST00000377654.3
ENST00000397659.4
tectonic family member 1
chr6_+_79577189 11.11 ENST00000369940.2
interleukin-1 receptor-associated kinase 1 binding protein 1
chr10_-_120514720 11.03 ENST00000369151.3
ENST00000340214.4
CDK2-associated, cullin domain 1
chr11_-_62521614 10.90 ENST00000527994.1
ENST00000394807.3
zinc finger and BTB domain containing 3
chr1_-_40157345 10.88 ENST00000372844.3
hippocalcin like 4
chr2_-_27851843 10.79 ENST00000324364.3
coiled-coil domain containing 121
chr9_-_138391692 10.69 ENST00000429260.2
chromosome 9 open reading frame 116
chr12_+_100660909 10.67 ENST00000549687.1
SCY1-like 2 (S. cerevisiae)
chr18_+_54318566 10.63 ENST00000589935.1
ENST00000357574.3
WD repeat domain 7
chrX_-_48693955 10.54 ENST00000218230.5
proprotein convertase subtilisin/kexin type 1 inhibitor
chr1_-_85156090 10.42 ENST00000605755.1
ENST00000437941.2
synovial sarcoma, X breakpoint 2 interacting protein
chr15_+_67547113 10.41 ENST00000512104.1
ENST00000358767.3
ENST00000546225.1
IQ motif containing H
chr22_-_21482352 10.40 ENST00000329949.3
POM121 transmembrane nucleoporin-like 7
chr11_+_113185251 10.39 ENST00000529221.1
tetratricopeptide repeat domain 12
chr3_-_45883558 10.37 ENST00000445698.1
ENST00000296135.6
leucine zipper transcription factor-like 1
chr20_-_48532019 10.21 ENST00000289431.5
spermatogenesis associated 2
chr19_-_4723761 10.10 ENST00000597849.1
ENST00000598800.1
ENST00000602161.1
ENST00000597726.1
ENST00000601130.1
ENST00000262960.9
dipeptidyl-peptidase 9
chr5_-_73937244 10.08 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ectodermal-neural cortex 1 (with BTB domain)
chr15_+_67547163 10.08 ENST00000335894.4
IQ motif containing H
chr11_-_71791435 10.04 ENST00000351960.6
ENST00000541719.1
ENST00000535111.1
nuclear mitotic apparatus protein 1
chr1_-_169396646 10.00 ENST00000367806.3
coiled-coil domain containing 181
chr10_-_101190202 9.98 ENST00000543866.1
ENST00000370508.5
glutamic-oxaloacetic transaminase 1, soluble
chr11_-_47736896 9.95 ENST00000525123.1
ENST00000528244.1
ENST00000532595.1
ENST00000529154.1
ENST00000530969.1
ATP/GTP binding protein-like 2
chr10_-_99161033 9.93 ENST00000315563.6
ENST00000370992.4
ENST00000414986.1
ribosomal RNA processing 12 homolog (S. cerevisiae)
chr1_-_72748417 9.92 ENST00000357731.5
neuronal growth regulator 1
chr15_-_55700457 9.82 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
cell cycle progression 1
chr22_-_43485381 9.69 ENST00000331018.7
ENST00000266254.7
ENST00000445824.1
tubulin tyrosine ligase-like family, member 1
chr18_+_32621324 9.42 ENST00000300249.5
ENST00000538170.2
ENST00000588910.1
microtubule-associated protein, RP/EB family, member 2
chr19_-_10679697 9.40 ENST00000335766.2
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr19_-_10679644 9.35 ENST00000393599.2
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr3_-_155461515 9.20 ENST00000399242.2
CDNA FLJ26134 fis, clone TMS03713; Uncharacterized protein
chr2_+_219575543 9.12 ENST00000457313.1
ENST00000415717.1
ENST00000392102.1
tubulin tyrosine ligase-like family, member 4
chr18_+_54318616 9.02 ENST00000254442.3
WD repeat domain 7
chr12_+_70132632 8.89 ENST00000378815.6
ENST00000483530.2
ENST00000325555.9
RAB3A interacting protein
chr2_+_27193480 8.86 ENST00000233121.2
ENST00000405074.3
microtubule-associated protein, RP/EB family, member 3
chr18_-_32957260 8.85 ENST00000587422.1
ENST00000306346.1
ENST00000589332.1
ENST00000586687.1
ENST00000585522.1
zinc finger protein 396
chr11_-_71791518 8.78 ENST00000537217.1
ENST00000366394.3
ENST00000358965.6
ENST00000546131.1
ENST00000543937.1
ENST00000368959.5
ENST00000541641.1
nuclear mitotic apparatus protein 1
chr19_-_36822595 8.78 ENST00000585356.1
ENST00000438368.2
ENST00000590622.1
long intergenic non-protein coding RNA 665
chr19_+_52693259 8.74 ENST00000322088.6
ENST00000454220.2
ENST00000444322.2
ENST00000477989.1
protein phosphatase 2, regulatory subunit A, alpha
chr7_+_86273218 8.69 ENST00000361669.2
glutamate receptor, metabotropic 3
chr3_-_105587879 8.68 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr16_+_57406368 8.63 ENST00000006053.6
ENST00000563383.1
chemokine (C-X3-C motif) ligand 1
chr15_+_71185148 8.59 ENST00000443425.2
ENST00000560755.1
leucine rich repeat containing 49
chr14_-_88459182 8.53 ENST00000544807.2
galactosylceramidase
chr2_-_175870085 8.52 ENST00000409156.3
chimerin 1
chr19_-_55690758 8.49 ENST00000590851.1
synaptotagmin V
chrX_+_73164149 8.38 ENST00000602938.1
ENST00000602294.1
ENST00000602920.1
ENST00000602737.1
ENST00000602772.1
JPX transcript, XIST activator (non-protein coding)
chr1_-_45140074 8.36 ENST00000420706.1
ENST00000372235.3
ENST00000372242.3
ENST00000372243.3
ENST00000372244.3
transmembrane protein 53
chr3_+_49591881 8.34 ENST00000296452.4
bassoon presynaptic cytomatrix protein
chr2_-_219537134 8.31 ENST00000295704.2
ring finger protein 25
chr7_+_156433396 8.31 ENST00000432459.2
ring finger protein 32
chr16_+_16429787 8.31 ENST00000331436.4
ENST00000541593.1
Protein PKD1P1
chr11_+_107461948 8.30 ENST00000265840.7
ENST00000443271.2
ELMO/CED-12 domain containing 1
chr1_-_45308616 8.28 ENST00000447098.2
ENST00000372192.3
patched 2
chr9_-_90589402 8.28 ENST00000375871.4
ENST00000605159.1
ENST00000336654.5
cyclin-dependent kinase 20
chr19_+_56186557 8.25 ENST00000270460.6
epsin 1
chr11_+_450255 8.25 ENST00000308020.5
phosphatidylserine synthase 2
chr19_+_56186606 8.22 ENST00000085079.7
epsin 1
chr21_-_47743719 8.21 ENST00000397680.1
ENST00000445935.1
ENST00000397685.4
ENST00000397682.3
ENST00000291691.7
chromosome 21 open reading frame 58
chr7_+_156433461 8.11 ENST00000317955.5
ENST00000405335.1
ring finger protein 32
chr19_+_58962971 8.06 ENST00000336614.4
ENST00000545523.1
ENST00000599194.1
ENST00000598244.1
ENST00000599193.1
ENST00000594214.1
ENST00000391696.1
zinc finger protein 324B
chr1_+_118148556 8.05 ENST00000369448.3
family with sequence similarity 46, member C
chr3_+_32726774 8.03 ENST00000538368.1
CCR4-NOT transcription complex, subunit 10
chrX_+_129473859 8.01 ENST00000424447.1
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr1_+_155829286 7.99 ENST00000368324.4
synaptotagmin XI
chr10_+_12171636 7.98 ENST00000379051.1
ENST00000379033.3
ENST00000441368.1
ENST00000298428.9
ENST00000304267.8
Sec61 alpha 2 subunit (S. cerevisiae)
chr2_+_220110177 7.91 ENST00000409638.3
ENST00000396738.2
ENST00000409516.3
serine/threonine kinase 16
chr13_-_31736132 7.90 ENST00000429785.2
heat shock 105kDa/110kDa protein 1
chr17_-_64187973 7.87 ENST00000583358.1
ENST00000392769.2
centrosomal protein 112kDa
chr10_-_53459319 7.83 ENST00000331173.4
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
chr2_+_48541776 7.79 ENST00000413569.1
ENST00000340553.3
forkhead box N2
chr16_-_29479154 7.78 ENST00000549950.1
Uncharacterized protein
chr19_+_35634146 7.74 ENST00000586063.1
ENST00000270310.2
ENST00000588265.1
FXYD domain containing ion transport regulator 7
chr9_+_131218336 7.66 ENST00000372814.3
outer dense fiber of sperm tails 2
chr7_+_149535455 7.64 ENST00000223210.4
ENST00000460379.1
zinc finger protein 862
chr7_+_154002189 7.62 ENST00000332007.3
dipeptidyl-peptidase 6
chr1_+_28052456 7.62 ENST00000373954.6
ENST00000419687.2
family with sequence similarity 76, member A
chr2_-_62733476 7.58 ENST00000335390.5
transmembrane protein 17
chr7_+_89874483 7.51 ENST00000389297.4
ENST00000316089.8
chromosome 7 open reading frame 63

Network of associatons between targets according to the STRING database.

First level regulatory network of RFX7_RFX4_RFX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
50.8 203.2 GO:0090299 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
12.0 84.2 GO:0060294 cilium movement involved in cell motility(GO:0060294)
10.4 31.3 GO:2000777 positive regulation of oocyte maturation(GO:1900195) negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
9.8 48.8 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
9.3 27.9 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
8.9 26.8 GO:0018307 enzyme active site formation(GO:0018307) tRNA thio-modification(GO:0034227)
8.6 25.8 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
8.4 25.3 GO:0071988 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
8.1 40.4 GO:0035617 stress granule disassembly(GO:0035617)
7.2 50.7 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539)
6.1 24.3 GO:0060613 fat pad development(GO:0060613)
6.1 18.2 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
5.6 39.4 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
5.6 22.4 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
5.4 32.7 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
4.5 22.4 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
4.2 12.7 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
4.1 49.0 GO:0036158 outer dynein arm assembly(GO:0036158)
3.6 21.4 GO:0018095 protein polyglutamylation(GO:0018095)
3.5 17.4 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
3.3 10.0 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
3.3 19.9 GO:0051013 microtubule severing(GO:0051013)
3.3 9.9 GO:0035610 protein side chain deglutamylation(GO:0035610)
3.3 19.8 GO:0033133 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
3.1 55.6 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
3.0 8.9 GO:0001694 histamine biosynthetic process(GO:0001694)
3.0 8.9 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
2.8 24.9 GO:0003351 epithelial cilium movement(GO:0003351)
2.7 8.0 GO:1905154 negative regulation of membrane invagination(GO:1905154)
2.4 109.7 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
2.4 7.3 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
2.4 4.7 GO:0070286 axonemal dynein complex assembly(GO:0070286)
2.3 16.4 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
2.3 4.6 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
2.3 6.8 GO:0050902 leukocyte adhesive activation(GO:0050902)
2.3 11.3 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
2.2 8.7 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
2.1 14.9 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
2.1 19.2 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
2.1 10.4 GO:1903564 regulation of protein localization to cilium(GO:1903564)
1.9 24.6 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
1.9 9.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
1.9 5.6 GO:1905224 clathrin-coated pit assembly(GO:1905224)
1.7 18.8 GO:0048102 autophagic cell death(GO:0048102)
1.7 48.9 GO:0006884 cell volume homeostasis(GO:0006884)
1.6 9.6 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
1.6 4.8 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
1.6 4.7 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
1.5 15.3 GO:0008343 adult feeding behavior(GO:0008343)
1.5 11.9 GO:0015693 magnesium ion transport(GO:0015693)
1.5 14.8 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.4 8.6 GO:0098535 de novo centriole assembly(GO:0098535)
1.4 4.3 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
1.4 16.8 GO:0030321 transepithelial chloride transport(GO:0030321)
1.4 12.6 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
1.3 6.7 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
1.3 14.6 GO:0022008 neurogenesis(GO:0022008)
1.3 16.9 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
1.3 30.6 GO:0006895 Golgi to endosome transport(GO:0006895)
1.3 25.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
1.2 9.7 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
1.2 2.4 GO:0061055 myotome development(GO:0061055)
1.2 2.4 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
1.2 2.4 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
1.2 4.7 GO:0035625 regulation of epinephrine secretion(GO:0014060) negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) epinephrine secretion(GO:0048242)
1.1 17.1 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
1.1 4.5 GO:1904450 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
1.1 10.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
1.1 8.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
1.1 52.5 GO:0007019 microtubule depolymerization(GO:0007019)
1.1 6.5 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
1.1 3.2 GO:0061074 regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
1.1 6.4 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
1.0 2.1 GO:0061511 centriole elongation(GO:0061511)
1.0 8.3 GO:0009957 epidermal cell fate specification(GO:0009957)
1.0 8.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
1.0 15.3 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.9 8.5 GO:0030916 otic vesicle formation(GO:0030916)
0.9 13.8 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.9 3.6 GO:0048511 rhythmic process(GO:0048511)
0.9 7.2 GO:0007506 gonadal mesoderm development(GO:0007506)
0.9 15.2 GO:0019374 galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374)
0.9 4.4 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.9 12.9 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.9 8.5 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.8 5.8 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.8 2.4 GO:0097359 UDP-glucosylation(GO:0097359)
0.8 5.5 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.8 8.6 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.8 8.4 GO:0015886 heme transport(GO:0015886)
0.8 1.5 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.8 4.5 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.7 8.9 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.7 2.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.7 4.3 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.7 12.8 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.7 25.9 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.7 2.7 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.7 8.1 GO:0008037 binding of sperm to zona pellucida(GO:0007339) cell recognition(GO:0008037) cell-cell recognition(GO:0009988) sperm-egg recognition(GO:0035036)
0.7 21.7 GO:0008045 motor neuron axon guidance(GO:0008045)
0.7 9.1 GO:0002021 response to dietary excess(GO:0002021)
0.6 3.9 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.6 6.4 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.6 1.3 GO:0045144 meiotic sister chromatid segregation(GO:0045144)
0.6 1.9 GO:0007288 sperm axoneme assembly(GO:0007288)
0.6 3.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.6 27.4 GO:0060612 adipose tissue development(GO:0060612)
0.6 7.4 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.6 21.3 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.6 2.4 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.6 8.7 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.6 4.5 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.6 8.8 GO:0045475 locomotor rhythm(GO:0045475)
0.5 3.3 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.5 6.5 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.5 2.6 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.5 15.1 GO:0097120 receptor localization to synapse(GO:0097120)
0.5 4.6 GO:0051026 chiasma assembly(GO:0051026)
0.5 2.5 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.5 22.1 GO:0016579 protein deubiquitination(GO:0016579)
0.5 9.2 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.5 1.9 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.5 11.2 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.5 1.9 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.5 21.9 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.4 17.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.4 1.3 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.4 1.3 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.4 2.1 GO:0022605 ovarian cumulus expansion(GO:0001550) oogenesis stage(GO:0022605) fused antrum stage(GO:0048165)
0.4 3.2 GO:0070986 left/right axis specification(GO:0070986)
0.4 4.0 GO:0015871 choline transport(GO:0015871)
0.4 7.7 GO:0071420 cellular response to histamine(GO:0071420)
0.4 8.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.4 7.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.4 0.8 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.3 1.0 GO:0044805 late nucleophagy(GO:0044805)
0.3 32.3 GO:0007286 spermatid development(GO:0007286)
0.3 16.6 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.3 2.7 GO:0016926 protein desumoylation(GO:0016926)
0.3 6.3 GO:0097484 dendrite extension(GO:0097484)
0.3 9.3 GO:0015695 organic cation transport(GO:0015695)
0.3 1.2 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.3 1.7 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.3 1.9 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.3 11.4 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.2 7.4 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.2 3.8 GO:0006004 fucose metabolic process(GO:0006004)
0.2 14.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.2 1.1 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.2 3.3 GO:0002638 negative regulation of immunoglobulin production(GO:0002638)
0.2 4.4 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.2 8.3 GO:0035418 protein localization to synapse(GO:0035418)
0.2 4.1 GO:0003334 keratinocyte development(GO:0003334)
0.2 2.1 GO:0015889 cobalamin transport(GO:0015889)
0.2 3.7 GO:0071625 vocalization behavior(GO:0071625)
0.2 12.5 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.2 8.4 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.2 5.4 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.2 3.2 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.2 6.3 GO:0030317 sperm motility(GO:0030317)
0.2 11.0 GO:0051865 protein autoubiquitination(GO:0051865)
0.2 11.1 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.2 7.6 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.2 4.0 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.2 5.8 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.2 8.4 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.2 31.5 GO:0060271 cilium morphogenesis(GO:0060271)
0.2 1.8 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.2 6.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.2 0.7 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.2 4.1 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.2 0.8 GO:0030205 dermatan sulfate metabolic process(GO:0030205) dermatan sulfate biosynthetic process(GO:0030208)
0.2 6.1 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.2 3.7 GO:0010669 epithelial structure maintenance(GO:0010669)
0.2 6.3 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.2 5.4 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.2 8.3 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.2 1.2 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 9.9 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 15.5 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 5.9 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 12.2 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 5.3 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 8.4 GO:0009060 aerobic respiration(GO:0009060)
0.1 1.1 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.1 0.9 GO:0071372 response to light intensity(GO:0009642) cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 1.2 GO:0015074 DNA integration(GO:0015074)
0.1 5.1 GO:0016266 O-glycan processing(GO:0016266)
0.1 8.1 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 3.3 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.1 0.6 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 2.9 GO:0060996 dendritic spine development(GO:0060996)
0.1 0.4 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.1 3.7 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.1 1.0 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.1 4.2 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.6 GO:0023021 termination of signal transduction(GO:0023021)
0.1 1.7 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 2.8 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 1.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.7 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 0.9 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.2 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.1 2.1 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 1.8 GO:0045026 plasma membrane fusion(GO:0045026)
0.1 1.1 GO:0007635 chemosensory behavior(GO:0007635)
0.1 4.5 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.1 1.1 GO:0001573 ganglioside metabolic process(GO:0001573)
0.1 1.5 GO:0010107 potassium ion import(GO:0010107)
0.1 0.5 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1 1.2 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 2.2 GO:0001961 positive regulation of cytokine-mediated signaling pathway(GO:0001961)
0.1 0.2 GO:0016999 antibiotic metabolic process(GO:0016999) cellular amide catabolic process(GO:0043605)
0.1 7.2 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 1.9 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 15.6 GO:0098916 chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916)
0.0 0.8 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.3 GO:1990592 protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.9 GO:0016578 histone deubiquitination(GO:0016578)
0.0 4.6 GO:0021915 neural tube development(GO:0021915)
0.0 0.7 GO:0003094 glomerular filtration(GO:0003094)
0.0 5.4 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 2.4 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.7 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.1 GO:0051958 methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.0 0.9 GO:0032620 interleukin-17 production(GO:0032620)
0.0 2.0 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.0 0.1 GO:0035814 negative regulation of urine volume(GO:0035811) negative regulation of renal sodium excretion(GO:0035814)
0.0 1.5 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 3.9 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 1.2 GO:0014047 glutamate secretion(GO:0014047)
0.0 21.6 GO:0007417 central nervous system development(GO:0007417)
0.0 1.0 GO:0042552 myelination(GO:0042552)
0.0 1.6 GO:0060041 retina development in camera-type eye(GO:0060041)
0.0 5.7 GO:0045860 positive regulation of protein kinase activity(GO:0045860)
0.0 0.1 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.2 GO:1901661 quinone metabolic process(GO:1901661)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
8.4 25.3 GO:0061673 cortical microtubule(GO:0055028) mitotic spindle astral microtubule(GO:0061673)
7.1 99.7 GO:0005858 axonemal dynein complex(GO:0005858)
4.9 29.2 GO:0044447 axoneme part(GO:0044447)
4.1 32.7 GO:0045179 apical cortex(GO:0045179)
3.9 15.4 GO:0016939 kinesin II complex(GO:0016939)
3.8 19.2 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
3.8 45.3 GO:0033010 paranodal junction(GO:0033010)
3.2 22.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
3.1 18.8 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
3.1 18.5 GO:0002177 manchette(GO:0002177)
2.9 63.5 GO:0030992 intraciliary transport particle B(GO:0030992)
2.9 8.6 GO:0098536 deuterosome(GO:0098536)
2.5 7.4 GO:0044609 DBIRD complex(GO:0044609)
2.3 32.9 GO:0036038 MKS complex(GO:0036038)
2.2 4.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
2.2 6.5 GO:0002199 zona pellucida receptor complex(GO:0002199)
2.1 14.9 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
2.1 14.5 GO:0001520 outer dense fiber(GO:0001520)
2.1 39.1 GO:0031045 dense core granule(GO:0031045)
2.0 18.2 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
1.9 23.1 GO:0060077 inhibitory synapse(GO:0060077)
1.8 140.5 GO:0036126 sperm flagellum(GO:0036126)
1.5 36.1 GO:0034451 centriolar satellite(GO:0034451)
1.5 37.9 GO:0032391 photoreceptor connecting cilium(GO:0032391)
1.2 65.5 GO:0016235 aggresome(GO:0016235)
1.1 4.5 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
1.0 5.1 GO:0070847 core mediator complex(GO:0070847)
1.0 11.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
1.0 14.4 GO:0000242 pericentriolar material(GO:0000242)
0.9 6.4 GO:0097427 microtubule bundle(GO:0097427)
0.8 5.8 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.8 9.0 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.7 6.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.7 9.8 GO:0031209 SCAR complex(GO:0031209)
0.7 8.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.6 18.6 GO:0005682 U5 snRNP(GO:0005682)
0.6 24.9 GO:0036064 ciliary basal body(GO:0036064)
0.6 7.9 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.5 12.8 GO:0071565 nBAF complex(GO:0071565)
0.5 2.5 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.5 32.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.5 6.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.5 1.8 GO:0008091 spectrin(GO:0008091)
0.4 13.0 GO:0097546 ciliary base(GO:0097546)
0.4 14.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.4 11.3 GO:0035371 microtubule plus-end(GO:0035371)
0.4 1.3 GO:0000818 nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939)
0.4 4.6 GO:0032300 mismatch repair complex(GO:0032300)
0.4 69.6 GO:0030426 growth cone(GO:0030426)
0.4 19.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.4 2.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.4 5.1 GO:0001673 male germ cell nucleus(GO:0001673)
0.4 8.3 GO:0099738 cell cortex region(GO:0099738)
0.4 1.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.3 9.6 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.3 12.2 GO:1904115 axon cytoplasm(GO:1904115)
0.3 11.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 0.9 GO:0042612 MHC class I protein complex(GO:0042612)
0.3 24.5 GO:0034707 chloride channel complex(GO:0034707)
0.3 3.7 GO:0031252 cell leading edge(GO:0031252)
0.3 27.9 GO:0005882 intermediate filament(GO:0005882)
0.2 1.7 GO:0005869 dynactin complex(GO:0005869)
0.2 16.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.2 3.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.2 6.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.2 102.4 GO:0010008 endosome membrane(GO:0010008)
0.2 1.1 GO:1990130 EGO complex(GO:0034448) Iml1 complex(GO:1990130) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 77.8 GO:0005815 microtubule organizing center(GO:0005815)
0.2 57.6 GO:0045202 synapse(GO:0045202)
0.2 5.0 GO:0016592 mediator complex(GO:0016592)
0.1 16.4 GO:0043202 lysosomal lumen(GO:0043202)
0.1 6.6 GO:0000786 nucleosome(GO:0000786)
0.1 4.6 GO:0005859 muscle myosin complex(GO:0005859)
0.1 3.1 GO:0005771 multivesicular body(GO:0005771)
0.1 9.0 GO:0005902 microvillus(GO:0005902)
0.1 11.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 14.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 191.8 GO:0042995 cell projection(GO:0042995)
0.1 17.7 GO:0001650 fibrillar center(GO:0001650)
0.1 7.0 GO:0036477 somatodendritic compartment(GO:0036477)
0.1 6.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 14.3 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)
0.1 13.0 GO:0043209 myelin sheath(GO:0043209)
0.1 4.1 GO:0001533 cornified envelope(GO:0001533)
0.1 11.5 GO:0031225 anchored component of membrane(GO:0031225)
0.1 2.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 1.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 0.5 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 3.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 4.7 GO:0005811 lipid particle(GO:0005811)
0.1 16.3 GO:0005773 vacuole(GO:0005773)
0.1 10.9 GO:0005874 microtubule(GO:0005874)
0.1 4.3 GO:0005802 trans-Golgi network(GO:0005802)
0.1 8.2 GO:0016324 apical plasma membrane(GO:0016324)
0.0 4.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.6 GO:0005769 early endosome(GO:0005769)
0.0 0.9 GO:0030018 Z disc(GO:0030018)
0.0 0.0 GO:1903439 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648) calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
10.4 31.3 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
9.8 48.8 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
7.9 55.6 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
7.7 61.3 GO:0004565 beta-galactosidase activity(GO:0004565)
6.2 18.6 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
5.2 15.5 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
4.6 36.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
4.5 26.8 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
4.3 21.4 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
3.7 91.9 GO:0045503 dynein light chain binding(GO:0045503)
3.3 10.0 GO:0080130 phosphatidylserine decarboxylase activity(GO:0004609) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
3.3 19.9 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
3.3 19.8 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
2.9 23.4 GO:0050816 phosphothreonine binding(GO:0050816)
2.8 8.4 GO:0015439 heme-transporting ATPase activity(GO:0015439)
2.6 33.8 GO:0051011 microtubule minus-end binding(GO:0051011)
2.4 11.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
2.2 48.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
2.1 6.4 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
2.1 8.2 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
2.1 16.4 GO:0045504 dynein heavy chain binding(GO:0045504)
2.0 6.1 GO:0045322 unmethylated CpG binding(GO:0045322)
2.0 30.5 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
1.9 5.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
1.8 7.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
1.8 8.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.7 8.7 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
1.7 8.3 GO:0097108 hedgehog family protein binding(GO:0097108)
1.6 4.9 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
1.6 32.7 GO:0043560 insulin receptor substrate binding(GO:0043560)
1.6 4.7 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
1.4 7.2 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
1.4 16.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
1.4 16.4 GO:0048156 tau protein binding(GO:0048156)
1.3 6.7 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
1.3 6.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
1.2 3.7 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
1.2 11.9 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
1.2 18.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
1.2 12.8 GO:0004645 phosphorylase activity(GO:0004645)
1.1 34.3 GO:0043014 alpha-tubulin binding(GO:0043014)
1.1 4.5 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
1.1 80.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.9 21.3 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.9 19.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.9 3.6 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.9 16.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.8 2.4 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.8 3.8 GO:0070568 guanylyltransferase activity(GO:0070568)
0.7 5.8 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.7 2.1 GO:0015235 cobalamin transporter activity(GO:0015235)
0.7 2.7 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.7 4.0 GO:0039552 RIG-I binding(GO:0039552)
0.7 3.3 GO:0004974 leukotriene receptor activity(GO:0004974)
0.6 16.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.6 7.7 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.6 1.7 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.5 4.3 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.5 3.7 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.5 3.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.5 5.4 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.5 9.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.5 16.3 GO:0030332 cyclin binding(GO:0030332)
0.5 19.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.5 6.4 GO:0017136 NAD-dependent histone deacetylase activity(GO:0017136)
0.5 12.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.4 19.3 GO:0030552 cAMP binding(GO:0030552)
0.4 11.4 GO:0048487 beta-tubulin binding(GO:0048487)
0.4 7.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.4 0.8 GO:0032356 oxidized DNA binding(GO:0032356)
0.3 7.3 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.3 8.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.3 3.7 GO:0030274 LIM domain binding(GO:0030274)
0.3 9.3 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.3 5.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.3 1.2 GO:0035473 lipase binding(GO:0035473)
0.3 20.8 GO:0030276 clathrin binding(GO:0030276)
0.3 6.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.3 11.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.3 3.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.3 19.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.3 4.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.3 0.8 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.3 5.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.3 64.9 GO:0008017 microtubule binding(GO:0008017)
0.3 4.6 GO:0030983 mismatched DNA binding(GO:0030983)
0.3 6.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 4.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 5.6 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.3 4.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.3 2.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.3 8.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.2 7.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.2 1.9 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.2 14.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.2 4.0 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.2 1.9 GO:0016595 glutamate binding(GO:0016595)
0.2 5.6 GO:0071949 FAD binding(GO:0071949)
0.2 6.5 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.2 10.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.2 2.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.2 9.5 GO:0015631 tubulin binding(GO:0015631)
0.2 1.3 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.2 1.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.2 2.2 GO:0031433 telethonin binding(GO:0031433)
0.2 2.4 GO:0046790 virion binding(GO:0046790)
0.2 8.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 1.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 2.7 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.2 2.9 GO:0016805 dipeptidase activity(GO:0016805)
0.2 8.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.2 1.2 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.2 3.7 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.2 12.9 GO:0019843 rRNA binding(GO:0019843)
0.2 8.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.2 0.9 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 2.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.9 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 0.4 GO:0015616 DNA translocase activity(GO:0015616)
0.1 2.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 1.1 GO:0031386 protein tag(GO:0031386)
0.1 2.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 8.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 1.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 10.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.1 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 2.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 18.4 GO:0051015 actin filament binding(GO:0051015)
0.1 7.3 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.1 1.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 1.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 4.5 GO:0001618 virus receptor activity(GO:0001618)
0.1 8.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 2.2 GO:0001671 ATPase activator activity(GO:0001671)
0.1 8.4 GO:0005178 integrin binding(GO:0005178)
0.1 0.6 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 2.3 GO:0043022 ribosome binding(GO:0043022)
0.0 4.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 6.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.8 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.0 10.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 2.6 GO:0004497 monooxygenase activity(GO:0004497)
0.0 1.3 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.5 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 4.2 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.9 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.6 GO:0016798 hydrolase activity, acting on glycosyl bonds(GO:0016798)
0.0 1.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 10.1 GO:0008047 enzyme activator activity(GO:0008047)
0.0 0.7 GO:0008143 poly(A) binding(GO:0008143)
0.0 1.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 1.8 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.2 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 4.2 GO:0003779 actin binding(GO:0003779)
0.0 0.0 GO:0031716 calcitonin receptor activity(GO:0004948) calcitonin receptor binding(GO:0031716)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 2.9 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
1.0 25.2 PID ARF 3PATHWAY Arf1 pathway
0.8 32.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.7 25.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.6 17.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.4 40.2 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.4 23.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.3 19.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.3 21.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.3 3.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.3 20.2 PID PLK1 PATHWAY PLK1 signaling events
0.3 7.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.3 14.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.3 19.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.3 12.8 PID ERBB4 PATHWAY ErbB4 signaling events
0.2 8.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 11.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2 4.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 19.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.2 3.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 4.8 PID NECTIN PATHWAY Nectin adhesion pathway
0.2 4.9 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 3.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 6.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 3.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 3.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 2.0 PID IL27 PATHWAY IL27-mediated signaling events
0.1 6.2 PID LKB1 PATHWAY LKB1 signaling events
0.1 1.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 1.6 PID FGF PATHWAY FGF signaling pathway
0.1 3.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 1.9 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 1.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 0.6 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 1.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 2.0 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 2.1 PID BMP PATHWAY BMP receptor signaling
0.0 0.6 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 3.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 25.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
1.4 39.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
1.4 32.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
1.2 24.9 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
1.0 70.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.9 8.5 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.9 8.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.7 16.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.6 14.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.5 8.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.5 8.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.4 5.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.4 11.0 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.4 11.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.4 29.7 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.4 12.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.4 23.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.4 10.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.4 2.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.3 4.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.3 2.2 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.3 2.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.3 11.1 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.2 7.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 9.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 4.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 4.9 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.2 8.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.2 4.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.2 1.7 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.2 3.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.2 4.1 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.2 6.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 4.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 4.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 2.7 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 7.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 3.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 3.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 4.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 2.9 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 8.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 5.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 5.9 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 1.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 2.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 8.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 2.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.6 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 1.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 15.6 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 2.2 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.6 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 1.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.1 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.0 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes