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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for RREB1

Z-value: 0.80

Motif logo

Transcription factors associated with RREB1

Gene Symbol Gene ID Gene Info
ENSG00000124782.15 ras responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RREB1hg19_v2_chr6_+_7108210_71082640.171.1e-02Click!

Activity profile of RREB1 motif

Sorted Z-values of RREB1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_447226 12.63 ENST00000433358.1
NME/NM23 nucleoside diphosphate kinase 4
chrX_-_151903101 11.75 ENST00000393900.3
melanoma antigen family A, 12
chrX_-_151903184 11.75 ENST00000357916.4
ENST00000393869.3
melanoma antigen family A, 12
chr16_+_447209 11.55 ENST00000382940.4
ENST00000219479.2
NME/NM23 nucleoside diphosphate kinase 4
chrX_+_151903207 10.55 ENST00000370287.3
chondrosarcoma associated gene 1
chrX_+_151867214 9.03 ENST00000329342.5
ENST00000412733.1
ENST00000457643.1
melanoma antigen family A, 6
chrX_+_151903253 9.00 ENST00000452779.2
ENST00000370291.2
chondrosarcoma associated gene 1
chrX_-_151938171 7.33 ENST00000393902.3
ENST00000417212.1
ENST00000370278.3
melanoma antigen family A, 3
chrX_-_151922340 6.12 ENST00000370284.1
ENST00000543232.1
ENST00000393876.1
ENST00000393872.3
melanoma antigen family A, 2
chr1_+_46668994 5.81 ENST00000371980.3
leucine rich adaptor protein 1
chrX_+_151883090 5.79 ENST00000370293.2
ENST00000423993.1
ENST00000447530.1
ENST00000458057.1
ENST00000331220.2
ENST00000422085.1
ENST00000453150.1
ENST00000409560.1
melanoma antigen family A, 2B
chrX_+_151081351 4.78 ENST00000276344.2
melanoma antigen family A, 4
chr6_+_151646800 4.66 ENST00000354675.6
A kinase (PRKA) anchor protein 12
chr7_-_19157248 4.64 ENST00000242261.5
twist family bHLH transcription factor 1
chr8_+_144816303 4.41 ENST00000533004.1
FAM83H antisense RNA 1 (head to head)
chr19_-_6720686 4.36 ENST00000245907.6
complement component 3
chr7_+_75932863 4.26 ENST00000429938.1
heat shock 27kDa protein 1
chr12_+_54447637 4.26 ENST00000609810.1
ENST00000430889.2
homeobox C4
Homeobox protein Hox-C4
chrX_+_153813407 4.09 ENST00000443287.2
ENST00000333128.3
cancer/testis antigen 1A
chr10_+_17271266 3.74 ENST00000224237.5
vimentin
chr11_+_71791693 3.53 ENST00000289488.2
ENST00000447974.1
leucine rich transmembrane and O-methyltransferase domain containing
chrX_-_153847522 3.36 ENST00000328435.2
ENST00000359887.4
cancer/testis antigen 1B
chrX_-_153881842 3.36 ENST00000369585.3
ENST00000247306.4
cancer/testis antigen 2
chr11_+_69455855 3.29 ENST00000227507.2
ENST00000536559.1
cyclin D1
chrX_-_151307020 3.22 ENST00000370323.4
ENST00000244096.3
ENST00000427322.2
melanoma antigen family A, 10
chr17_-_39677971 3.10 ENST00000393976.2
keratin 15
chr12_+_96588279 3.00 ENST00000552142.1
ELK3, ETS-domain protein (SRF accessory protein 2)
chr11_+_86511569 2.96 ENST00000441050.1
protease, serine, 23
chr12_-_53074182 2.89 ENST00000252244.3
keratin 1
chr1_-_204380919 2.82 ENST00000367188.4
protein phosphatase 1, regulatory subunit 15B
chr4_+_74735102 2.79 ENST00000395761.3
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr3_+_154797877 2.74 ENST00000462745.1
ENST00000493237.1
membrane metallo-endopeptidase
chr11_+_46402744 2.72 ENST00000533952.1
midkine (neurite growth-promoting factor 2)
chrX_+_102631844 2.68 ENST00000372634.1
ENST00000299872.7
nerve growth factor receptor (TNFRSF16) associated protein 1
chr12_-_56101647 2.54 ENST00000347027.6
ENST00000257879.6
ENST00000257880.7
ENST00000394230.2
ENST00000394229.2
integrin, alpha 7
chr4_+_123747979 2.49 ENST00000608478.1
fibroblast growth factor 2 (basic)
chrX_-_148669116 2.48 ENST00000243314.5
melanoma antigen family A, 9B
chr9_-_21994597 2.40 ENST00000579755.1
cyclin-dependent kinase inhibitor 2A
chr3_+_154797428 2.38 ENST00000460393.1
membrane metallo-endopeptidase
chr2_+_46926326 2.36 ENST00000394861.2
suppressor of cytokine signaling 5
chrX_-_100604184 2.36 ENST00000372902.3
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chrX_+_148863584 2.33 ENST00000439010.2
ENST00000298974.5
ENST00000522429.1
ENST00000519822.1
melanoma antigen family A, 9
chr9_-_13279563 2.25 ENST00000541718.1
multiple PDZ domain protein
chr9_-_21994344 2.25 ENST00000530628.2
ENST00000361570.3
cyclin-dependent kinase inhibitor 2A
chr17_-_66453562 2.25 ENST00000262139.5
ENST00000546360.1
WD repeat domain, phosphoinositide interacting 1
chrX_+_17755563 2.23 ENST00000380045.3
ENST00000380041.3
ENST00000380043.3
ENST00000398080.1
sex comb on midleg-like 1 (Drosophila)
chr2_+_48757278 2.19 ENST00000404752.1
ENST00000406226.1
stonin 1
chr9_-_13279406 2.19 ENST00000546205.1
multiple PDZ domain protein
chr8_+_28748099 2.18 ENST00000519047.1
homeobox containing 1
chr19_-_42759300 2.06 ENST00000222329.4
Ets2 repressor factor
chr19_+_55477711 2.04 ENST00000448584.2
ENST00000537859.1
ENST00000585500.1
ENST00000427260.2
ENST00000538819.1
ENST00000263437.6
NLR family, pyrin domain containing 2
chr19_+_55476620 2.03 ENST00000543010.1
ENST00000391721.4
ENST00000339757.7
NLR family, pyrin domain containing 2
chr17_-_72864739 2.03 ENST00000579893.1
ENST00000544854.1
ferredoxin reductase
chr19_+_35609380 2.00 ENST00000604621.1
FXYD domain containing ion transport regulator 3
chr13_-_37494365 1.96 ENST00000350148.5
SMAD family member 9
chr4_+_123747834 1.95 ENST00000264498.3
fibroblast growth factor 2 (basic)
chr13_-_37494391 1.94 ENST00000379826.4
SMAD family member 9
chr12_-_123849374 1.91 ENST00000602398.1
ENST00000602750.1
strawberry notch homolog 1 (Drosophila)
chr1_-_153538292 1.86 ENST00000497140.1
ENST00000368708.3
S100 calcium binding protein A2
chr16_-_3285144 1.85 ENST00000431561.3
ENST00000396870.4
zinc finger protein 200
chr19_-_3029011 1.85 ENST00000590536.1
ENST00000587137.1
ENST00000455444.2
ENST00000262953.6
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr12_+_96588143 1.85 ENST00000228741.3
ENST00000547249.1
ELK3, ETS-domain protein (SRF accessory protein 2)
chr22_+_32750872 1.83 ENST00000397468.1
ret finger protein-like 3
chr1_+_18958008 1.78 ENST00000420770.2
ENST00000400661.3
paired box 7
chr11_+_46403303 1.76 ENST00000407067.1
ENST00000395565.1
midkine (neurite growth-promoting factor 2)
chr19_-_3025614 1.76 ENST00000447365.2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr12_+_54402790 1.75 ENST00000040584.4
homeobox C8
chr11_+_46403194 1.71 ENST00000395569.4
ENST00000395566.4
midkine (neurite growth-promoting factor 2)
chr3_-_55521323 1.68 ENST00000264634.4
wingless-type MMTV integration site family, member 5A
chr21_+_44073916 1.64 ENST00000349112.3
ENST00000398224.3
phosphodiesterase 9A
chr9_-_13279589 1.63 ENST00000319217.7
multiple PDZ domain protein
chr9_-_14314066 1.61 ENST00000397575.3
nuclear factor I/B
chr9_-_14313893 1.60 ENST00000380921.3
ENST00000380959.3
nuclear factor I/B
chr6_+_7541808 1.55 ENST00000379802.3
desmoplakin
chr1_+_244998602 1.55 ENST00000411948.2
COX20 cytochrome C oxidase assembly factor
chr9_+_132427883 1.52 ENST00000372469.4
paired related homeobox 2
chr21_+_44073860 1.51 ENST00000335512.4
ENST00000539837.1
ENST00000291539.6
ENST00000380328.2
ENST00000398232.3
ENST00000398234.3
ENST00000398236.3
ENST00000328862.6
ENST00000335440.6
ENST00000398225.3
ENST00000398229.3
ENST00000398227.3
phosphodiesterase 9A
chr22_-_46450024 1.48 ENST00000396008.2
ENST00000333761.1
chromosome 22 open reading frame 26
chr6_+_7541845 1.48 ENST00000418664.2
desmoplakin
chr16_-_4588469 1.46 ENST00000588381.1
ENST00000563332.2
cell death-inducing p53 target 1
chr16_-_31439735 1.46 ENST00000287490.4
cytochrome c oxidase subunit VIa polypeptide 2
chr16_+_28889703 1.45 ENST00000357084.3
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr18_+_55102917 1.44 ENST00000491143.2
one cut homeobox 2
chr16_+_28834303 1.43 ENST00000340394.8
ENST00000325215.6
ENST00000395547.2
ENST00000336783.4
ENST00000382686.4
ENST00000564304.1
ataxin 2-like
chr10_+_115438920 1.42 ENST00000429617.1
ENST00000369331.4
caspase 7, apoptosis-related cysteine peptidase
chr1_+_154975110 1.41 ENST00000535420.1
ENST00000368426.3
zinc finger and BTB domain containing 7B
chr1_-_113249948 1.39 ENST00000339083.7
ENST00000369642.3
ras homolog family member C
chr13_+_60971427 1.39 ENST00000535286.1
ENST00000377881.2
tudor domain containing 3
chr19_-_51456198 1.39 ENST00000594846.1
kallikrein-related peptidase 5
chr16_+_28889801 1.38 ENST00000395503.4
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr13_-_74708372 1.38 ENST00000377666.4
Kruppel-like factor 12
chr19_+_3366547 1.38 ENST00000341919.3
ENST00000590282.1
ENST00000443272.2
nuclear factor I/C (CCAAT-binding transcription factor)
chr4_+_147560042 1.34 ENST00000281321.3
POU class 4 homeobox 2
chr7_+_114562172 1.34 ENST00000393486.1
ENST00000257724.3
MyoD family inhibitor domain containing
chr19_-_51456321 1.33 ENST00000391809.2
kallikrein-related peptidase 5
chr12_+_16064258 1.33 ENST00000524480.1
ENST00000531803.1
ENST00000532964.1
deoxyribose-phosphate aldolase (putative)
chr21_-_47648665 1.31 ENST00000450351.1
ENST00000522411.1
ENST00000356396.4
ENST00000397728.3
ENST00000457828.2
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr1_-_113249734 1.29 ENST00000484054.3
ENST00000369636.2
ENST00000369637.1
ENST00000285735.2
ENST00000369638.2
ras homolog family member C
chr1_-_113249678 1.29 ENST00000369633.2
ENST00000425265.2
ENST00000369632.2
ENST00000436685.2
ras homolog family member C
chrX_-_131352152 1.28 ENST00000342983.2
RAP2C, member of RAS oncogene family
chr1_-_17307173 1.27 ENST00000438542.1
ENST00000375535.3
microfibrillar-associated protein 2
chr19_-_19051927 1.26 ENST00000600077.1
homer homolog 3 (Drosophila)
chr16_+_28834531 1.25 ENST00000570200.1
ataxin 2-like
chr7_-_24797032 1.25 ENST00000409970.1
ENST00000409775.3
deafness, autosomal dominant 5
chrX_+_119495934 1.23 ENST00000218008.3
ENST00000361319.3
ENST00000539306.1
ATPase, Na+/K+ transporting, beta 4 polypeptide
chr2_+_105471969 1.21 ENST00000361360.2
POU class 3 homeobox 3
chr1_-_113392399 1.21 ENST00000449572.2
ENST00000433505.1
RP11-426L16.8
chr11_+_111896320 1.21 ENST00000531306.1
ENST00000537636.1
dihydrolipoamide S-acetyltransferase
chr15_+_63481668 1.18 ENST00000321437.4
ENST00000559006.1
ENST00000448330.2
RAB8B, member RAS oncogene family
chr15_-_35088340 1.18 ENST00000290378.4
actin, alpha, cardiac muscle 1
chr19_+_48867652 1.18 ENST00000344846.2
synaptogyrin 4
chr12_-_131323754 1.17 ENST00000261653.6
syntaxin 2
chr5_+_150591678 1.17 ENST00000523466.1
GM2 ganglioside activator
chr10_+_13628933 1.16 ENST00000417658.1
ENST00000320054.4
pre-mRNA processing factor 18
chr19_+_51358166 1.14 ENST00000601503.1
ENST00000326003.2
ENST00000597286.1
ENST00000597483.1
kallikrein-related peptidase 3
chr15_-_43513187 1.14 ENST00000540029.1
ENST00000441366.2
erythrocyte membrane protein band 4.2
chr14_+_74353320 1.13 ENST00000540593.1
ENST00000555730.1
zinc finger protein 410
chr19_+_51358191 1.12 ENST00000593997.1
ENST00000595952.1
ENST00000360617.3
ENST00000598145.1
kallikrein-related peptidase 3
chr19_-_15560730 1.11 ENST00000389282.4
ENST00000263381.7
widely interspaced zinc finger motifs
chr6_+_7107830 1.11 ENST00000379933.3
ras responsive element binding protein 1
chr19_-_51456344 1.11 ENST00000336334.3
ENST00000593428.1
kallikrein-related peptidase 5
chr17_+_77751931 1.10 ENST00000310942.4
ENST00000269399.5
chromobox homolog 2
chr13_-_76056250 1.08 ENST00000377636.3
ENST00000431480.2
ENST00000377625.2
ENST00000425511.1
TBC1 domain family, member 4
chr16_+_69599861 1.07 ENST00000354436.2
nuclear factor of activated T-cells 5, tonicity-responsive
chr19_+_36157715 1.06 ENST00000379013.2
ENST00000222275.2
uroplakin 1A
chr16_+_1728305 1.06 ENST00000569765.1
hematological and neurological expressed 1-like
chr3_+_186435137 1.06 ENST00000447445.1
kininogen 1
chr17_-_58156273 1.06 ENST00000593228.1
ENST00000585976.1
ENST00000593097.1
ENST00000184956.6
HEAT repeat containing 6
chr2_+_192542850 1.05 ENST00000410026.2
nucleic acid binding protein 1
chr8_+_32406137 1.03 ENST00000521670.1
neuregulin 1
chr6_+_168227611 1.02 ENST00000344191.4
ENST00000351017.4
ENST00000392108.3
ENST00000366806.2
ENST00000392112.1
ENST00000400824.4
ENST00000447894.2
ENST00000400822.3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
chr12_-_56120865 1.02 ENST00000548898.1
ENST00000552067.1
CD63 molecule
chr18_+_9334786 1.00 ENST00000581641.1
twisted gastrulation BMP signaling modulator 1
chr11_-_74109422 0.99 ENST00000298198.4
phosphoglucomutase 2-like 1
chr17_+_79373540 0.97 ENST00000307745.7
BAH and coiled-coil domain-containing protein 1
chr12_-_44152551 0.97 ENST00000416848.2
ENST00000550784.1
ENST00000547156.1
ENST00000549868.1
ENST00000553166.1
ENST00000551923.1
ENST00000431332.3
ENST00000344862.5
pseudouridylate synthase 7 homolog (S. cerevisiae)-like
chr12_-_131323719 0.97 ENST00000392373.2
syntaxin 2
chr4_-_96470350 0.96 ENST00000504962.1
ENST00000453304.1
ENST00000506749.1
unc-5 homolog C (C. elegans)
chr20_+_48599506 0.95 ENST00000244050.2
snail family zinc finger 1
chr19_-_51222707 0.95 ENST00000391814.1
SH3 and multiple ankyrin repeat domains 1
chr10_-_75415825 0.95 ENST00000394810.2
synaptopodin 2-like
chr12_-_56120838 0.94 ENST00000548160.1
CD63 molecule
chr19_+_7828035 0.94 ENST00000327325.5
ENST00000394122.2
ENST00000248228.4
ENST00000334806.5
ENST00000359059.5
ENST00000357361.2
ENST00000596363.1
ENST00000595751.1
ENST00000596707.1
ENST00000597522.1
ENST00000595496.1
C-type lectin domain family 4, member M
chr9_+_131174024 0.92 ENST00000420034.1
ENST00000372842.1
cerebral endothelial cell adhesion molecule
chr16_+_68771128 0.92 ENST00000261769.5
ENST00000422392.2
cadherin 1, type 1, E-cadherin (epithelial)
chr9_-_14722715 0.91 ENST00000380911.3
cerberus 1, DAN family BMP antagonist
chr2_+_85843252 0.90 ENST00000409025.1
ENST00000409470.1
ENST00000323701.6
ENST00000409766.3
ubiquitin specific peptidase 39
chr2_-_54087066 0.89 ENST00000394705.2
ENST00000352846.3
ENST00000406625.2
G protein-coupled receptor 75
GPR75-ASB3 readthrough
Ankyrin repeat and SOCS box protein 3
chr1_+_154975258 0.89 ENST00000417934.2
zinc finger and BTB domain containing 7B
chr17_+_41177220 0.89 ENST00000587250.2
ENST00000544533.1
Rho family GTPase 2
chr1_-_228604328 0.89 ENST00000355586.4
ENST00000366698.2
ENST00000520264.1
ENST00000479800.1
ENST00000295033.3
tripartite motif containing 17
chr4_+_190992087 0.88 ENST00000553598.1
double homeobox 4 like 7
chr2_+_223289208 0.88 ENST00000321276.7
sphingosine-1-phosphate phosphatase 2
chr1_+_18957500 0.86 ENST00000375375.3
paired box 7
chr2_-_220108309 0.86 ENST00000409640.1
galactosidase, beta 1-like
chr18_+_9334755 0.86 ENST00000262120.5
twisted gastrulation BMP signaling modulator 1
chr11_-_89224488 0.85 ENST00000534731.1
ENST00000527626.1
NADPH oxidase 4
chr19_-_51192661 0.85 ENST00000391813.1
SH3 and multiple ankyrin repeat domains 1
chr1_+_157963063 0.83 ENST00000360089.4
ENST00000368173.3
ENST00000392272.2
kin of IRRE like (Drosophila)
chrX_+_149737046 0.82 ENST00000370396.2
ENST00000542741.1
ENST00000543350.1
ENST00000424519.1
ENST00000413012.2
myotubularin 1
chr8_+_28748765 0.82 ENST00000355231.5
homeobox containing 1
chr1_-_201346761 0.80 ENST00000455702.1
ENST00000422165.1
ENST00000367318.5
ENST00000367320.2
ENST00000438742.1
ENST00000412633.1
ENST00000458432.2
ENST00000421663.2
ENST00000367322.1
ENST00000509001.1
troponin T type 2 (cardiac)
chr1_-_156470556 0.80 ENST00000489057.1
ENST00000348159.4
myocyte enhancer factor 2D
chr8_+_73449625 0.80 ENST00000523207.1
potassium voltage-gated channel, Shab-related subfamily, member 2
chr5_+_151151504 0.79 ENST00000356245.3
ENST00000507878.2
GTPase activating protein (SH3 domain) binding protein 1
chr18_+_33877654 0.79 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
formin homology 2 domain containing 3
chr17_-_46703826 0.76 ENST00000550387.1
ENST00000311177.5
homeobox B9
chr19_+_44085189 0.75 ENST00000562365.2
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr20_+_57875658 0.75 ENST00000371025.3
endothelin 3
chr7_+_91570165 0.75 ENST00000356239.3
ENST00000359028.2
ENST00000358100.2
A kinase (PRKA) anchor protein 9
chr16_+_67198683 0.75 ENST00000517685.1
ENST00000521374.1
ENST00000584272.1
heat shock transcription factor 4
chr7_-_154794763 0.74 ENST00000404141.1
PAX interacting (with transcription-activation domain) protein 1
chr3_+_192958914 0.73 ENST00000264735.2
ENST00000602513.1
HRAS-like suppressor
chr7_+_39125365 0.73 ENST00000559001.1
ENST00000464276.2
POU class 6 homeobox 2
chr17_-_62658186 0.73 ENST00000262435.9
SMAD specific E3 ubiquitin protein ligase 2
chr3_+_8775466 0.73 ENST00000343849.2
ENST00000397368.2
caveolin 3
chr18_+_77160282 0.72 ENST00000318065.5
ENST00000545796.1
ENST00000592223.1
ENST00000329101.4
ENST00000586434.1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr17_+_35849937 0.72 ENST00000394389.4
dual specificity phosphatase 14
chr12_-_6716569 0.72 ENST00000544040.1
ENST00000545942.1
chromodomain helicase DNA binding protein 4
chr8_+_32406179 0.71 ENST00000405005.3
neuregulin 1
chr5_+_151151471 0.71 ENST00000394123.3
ENST00000543466.1
GTPase activating protein (SH3 domain) binding protein 1
chr20_-_25062767 0.70 ENST00000429762.3
ENST00000444511.2
ENST00000376707.3
visual system homeobox 1
chr17_-_1733114 0.68 ENST00000305513.7
SET and MYND domain containing 4
chr7_-_38398721 0.68 ENST00000390346.2
T cell receptor gamma variable 3
chr4_+_190992387 0.68 ENST00000554906.2
ENST00000553820.2
double homeobox 4 like 7
chr1_-_161193349 0.68 ENST00000469730.2
ENST00000463273.1
ENST00000464492.1
ENST00000367990.3
ENST00000470459.2
ENST00000468465.1
ENST00000463812.1
apolipoprotein A-II
chr19_+_44084696 0.67 ENST00000562255.1
ENST00000569031.2
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr16_+_21169976 0.67 ENST00000572258.1
ENST00000261388.3
ENST00000451578.2
ENST00000572599.1
ENST00000577162.1
transmembrane protein 159
chr3_+_141205852 0.67 ENST00000286364.3
ENST00000452898.1
RAS p21 protein activator 2
chr2_+_28618532 0.67 ENST00000545753.1
FOS-like antigen 2
chrX_+_53078273 0.66 ENST00000332582.4
G protein-coupled receptor 173
chr4_+_164265035 0.66 ENST00000338566.3
neuropeptide Y receptor Y5
chr10_-_35379241 0.66 ENST00000374748.1
ENST00000374749.3
cullin 2
chr7_-_14028488 0.66 ENST00000405358.4
ets variant 1
chr11_-_96239990 0.65 ENST00000511243.2
JRKL antisense RNA 1
chr6_-_35480705 0.64 ENST00000229771.6
tubby like protein 1
chr5_-_35195338 0.64 ENST00000509839.1
prolactin receptor
chr1_-_156470515 0.64 ENST00000340875.5
ENST00000368240.2
ENST00000353795.3
myocyte enhancer factor 2D
chr10_-_121356518 0.63 ENST00000369092.4
TIA1 cytotoxic granule-associated RNA binding protein-like 1
chr7_-_154794621 0.63 ENST00000419436.1
ENST00000397192.1
PAX interacting (with transcription-activation domain) protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of RREB1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 24.2 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
1.5 4.6 GO:2000276 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
1.5 4.4 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
1.3 5.1 GO:0071492 cellular response to UV-A(GO:0071492)
1.1 4.3 GO:0099640 axo-dendritic protein transport(GO:0099640)
1.0 6.2 GO:0030421 defecation(GO:0030421)
0.9 2.8 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.7 2.2 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.7 4.0 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.7 2.6 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.6 3.8 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.6 4.4 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.6 1.8 GO:0050894 determination of affect(GO:0050894)
0.6 2.3 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.6 1.7 GO:1904933 cardiac right atrium morphogenesis(GO:0003213) negative regulation of melanin biosynthetic process(GO:0048022) positive regulation of anagen(GO:0051885) mediolateral intercalation(GO:0060031) cervix development(GO:0060067) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775) negative regulation of secondary metabolite biosynthetic process(GO:1900377) regulation of cell proliferation in midbrain(GO:1904933)
0.5 3.3 GO:0070141 response to UV-A(GO:0070141)
0.5 1.9 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.5 3.2 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.5 2.3 GO:0002778 antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778)
0.4 1.3 GO:0061074 regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
0.4 3.0 GO:0071896 protein localization to adherens junction(GO:0071896)
0.4 4.6 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.4 1.2 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.4 2.4 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.3 3.7 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.3 0.7 GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769)
0.3 2.3 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.3 4.7 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.3 5.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.3 2.8 GO:0006983 ER overload response(GO:0006983)
0.3 6.5 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.3 1.7 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.3 2.0 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.3 1.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.3 0.8 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.3 1.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.3 1.0 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.3 3.5 GO:0060117 auditory receptor cell development(GO:0060117)
0.2 0.7 GO:0048867 stem cell fate determination(GO:0048867)
0.2 1.2 GO:0072240 thick ascending limb development(GO:0072023) DCT cell differentiation(GO:0072069) metanephric thick ascending limb development(GO:0072233) metanephric DCT cell differentiation(GO:0072240)
0.2 0.9 GO:1900175 regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175)
0.2 0.7 GO:0060621 regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
0.2 2.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 2.7 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.2 1.0 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.2 0.8 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.2 1.2 GO:0072553 terminal button organization(GO:0072553)
0.2 1.2 GO:0090131 mesenchyme migration(GO:0090131)
0.2 3.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 1.0 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.2 1.0 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.2 0.9 GO:0046968 peptide antigen transport(GO:0046968)
0.2 0.7 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 0.7 GO:0035995 detection of muscle stretch(GO:0035995)
0.2 1.4 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.2 0.7 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.2 1.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.2 0.7 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.2 0.3 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.2 2.0 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1 0.7 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 1.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 1.3 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.1 1.0 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.1 0.4 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.1 0.9 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.1 0.4 GO:0006059 hexitol metabolic process(GO:0006059)
0.1 2.8 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 0.2 GO:0043385 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.1 1.5 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.8 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 4.1 GO:0050718 positive regulation of interleukin-1 beta secretion(GO:0050718)
0.1 0.3 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1 1.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.7 GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
0.1 4.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 2.1 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 2.0 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.6 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 1.4 GO:0007512 adult heart development(GO:0007512)
0.1 2.2 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.1 0.6 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.1 0.3 GO:1904847 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.1 0.3 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.1 0.5 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.1 0.4 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.1 1.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.4 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 2.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.9 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.3 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.1 1.6 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.4 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.5 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 1.0 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.6 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 0.3 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 1.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 3.0 GO:0032212 positive regulation of telomere maintenance via telomerase(GO:0032212)
0.1 1.9 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 1.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.9 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.1 0.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.1 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 0.4 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.4 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.1 GO:1904048 regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.1 0.5 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.1 0.8 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.9 GO:0034311 sphingosine metabolic process(GO:0006670) diol metabolic process(GO:0034311)
0.1 0.2 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.1 0.2 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 2.5 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.7 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0034971 histone H3-R17 methylation(GO:0034971)
0.0 0.5 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 1.9 GO:0043542 endothelial cell migration(GO:0043542)
0.0 1.1 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.6 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.0 0.5 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 1.8 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 4.1 GO:0070268 cornification(GO:0070268)
0.0 0.2 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 1.1 GO:0042311 vasodilation(GO:0042311)
0.0 0.7 GO:0003334 keratinocyte development(GO:0003334)
0.0 2.0 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.4 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.5 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.5 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 1.7 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 1.4 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.7 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.5 GO:0031424 keratinization(GO:0031424)
0.0 0.3 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.9 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 0.6 GO:0017145 stem cell division(GO:0017145)
0.0 1.5 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 4.3 GO:0051216 cartilage development(GO:0051216)
0.0 4.0 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.8 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.0 0.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 4.0 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.1 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.6 GO:0060113 inner ear receptor cell differentiation(GO:0060113)
0.0 0.9 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.1 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 1.7 GO:0048705 skeletal system morphogenesis(GO:0048705)
0.0 0.0 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.3 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.8 GO:0007588 excretion(GO:0007588)
0.0 0.4 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 0.3 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.5 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.4 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.8 GO:0097209 epidermal lamellar body(GO:0097209)
0.4 4.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.4 1.5 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.3 6.1 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.3 1.2 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.3 26.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.3 3.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.3 1.1 GO:0070876 SOSS complex(GO:0070876)
0.2 3.7 GO:0005916 fascia adherens(GO:0005916)
0.2 1.5 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.2 1.2 GO:0042643 actomyosin, actin portion(GO:0042643)
0.2 0.6 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.2 3.9 GO:0071141 SMAD protein complex(GO:0071141)
0.2 2.8 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.2 2.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 2.0 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 1.2 GO:0051286 cell tip(GO:0051286)
0.1 0.8 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.7 GO:0030891 VCB complex(GO:0030891)
0.1 0.9 GO:0016342 catenin complex(GO:0016342)
0.1 1.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 4.0 GO:0032420 stereocilium(GO:0032420)
0.1 1.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.1 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.4 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 1.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 4.3 GO:1904115 axon cytoplasm(GO:1904115)
0.1 0.3 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 2.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.8 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 11.3 GO:0005882 intermediate filament(GO:0005882)
0.1 3.0 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 0.3 GO:0071020 post-spliceosomal complex(GO:0071020)
0.1 1.1 GO:0035102 PRC1 complex(GO:0035102)
0.1 2.1 GO:0030673 axolemma(GO:0030673)
0.1 0.4 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 0.4 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.1 1.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 2.7 GO:0008305 integrin complex(GO:0008305)
0.1 3.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 6.8 GO:0042641 actomyosin(GO:0042641)
0.0 0.8 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.7 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.9 GO:0045178 basal part of cell(GO:0045178)
0.0 4.0 GO:0005903 brush border(GO:0005903)
0.0 3.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 2.2 GO:0031201 SNARE complex(GO:0031201)
0.0 2.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.9 GO:0002080 acrosomal membrane(GO:0002080)
0.0 2.0 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 3.5 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 1.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.0 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 3.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.3 GO:0042588 zymogen granule(GO:0042588)
0.0 1.8 GO:0005811 lipid particle(GO:0005811)
0.0 1.9 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 10.4 GO:0005925 focal adhesion(GO:0005925)
0.0 6.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.2 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 2.0 GO:0016605 PML body(GO:0016605)
0.0 0.6 GO:0031904 endosome lumen(GO:0031904)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.8 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 1.8 GO:0031674 I band(GO:0031674)
0.0 1.5 GO:0001650 fibrillar center(GO:0001650)
0.0 0.2 GO:0000781 chromosome, telomeric region(GO:0000781)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 24.2 GO:1901612 cardiolipin binding(GO:1901612)
1.6 4.8 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
1.4 4.3 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
1.4 4.1 GO:0032090 Pyrin domain binding(GO:0032090)
0.7 2.0 GO:0015039 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.6 3.7 GO:1990254 keratin filament binding(GO:1990254)
0.6 7.3 GO:0089720 caspase binding(GO:0089720)
0.6 1.8 GO:0031877 somatostatin receptor binding(GO:0031877)
0.6 1.7 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.5 1.5 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.5 3.5 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.4 1.1 GO:0070984 SET domain binding(GO:0070984)
0.3 3.0 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.3 3.0 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.3 4.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.3 3.9 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.3 4.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 3.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 2.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 5.5 GO:0071837 HMG box domain binding(GO:0071837)
0.2 0.7 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.2 1.0 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 0.9 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 2.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 0.7 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.2 1.0 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 4.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 1.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 3.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.9 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 0.5 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.9 GO:0016015 morphogen activity(GO:0016015)
0.1 0.6 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 1.9 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 3.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 1.2 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.8 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.9 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 4.9 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 0.8 GO:0030172 troponin C binding(GO:0030172)
0.1 0.5 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 2.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.3 GO:0030957 Tat protein binding(GO:0030957)
0.1 3.3 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 0.4 GO:0004335 galactokinase activity(GO:0004335)
0.1 0.7 GO:0071253 connexin binding(GO:0071253)
0.1 2.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 1.7 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.3 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.5 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.1 7.1 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 0.7 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.1 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.3 GO:0004803 transposase activity(GO:0004803)
0.1 0.5 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.9 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.9 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 1.4 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.1 1.0 GO:0016866 intramolecular transferase activity(GO:0016866)
0.1 1.9 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 1.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.9 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 1.0 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 1.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 2.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 5.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.7 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 2.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.4 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 2.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 6.8 GO:0008201 heparin binding(GO:0008201)
0.0 13.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 9.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.9 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 2.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 6.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 6.6 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 1.5 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 6.6 GO:0003924 GTPase activity(GO:0003924)
0.0 0.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.7 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.9 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.6 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0 0.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.3 GO:0001047 core promoter binding(GO:0001047)
0.0 0.2 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.1 GO:0004955 prostaglandin receptor activity(GO:0004955)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 3.9 PID ALK2 PATHWAY ALK2 signaling events
0.2 4.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 7.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 4.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 4.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 7.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 4.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 2.5 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 2.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 0.8 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 2.8 PID IL23 PATHWAY IL23-mediated signaling events
0.1 3.7 PID AURORA B PATHWAY Aurora B signaling
0.1 1.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 3.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.7 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 4.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 2.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.2 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 2.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.0 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.6 PID BMP PATHWAY BMP receptor signaling
0.0 1.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.8 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.0 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.6 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.7 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 24.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.4 4.7 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.2 4.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 4.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.2 5.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 3.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 2.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.1 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 4.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 3.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 2.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.8 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 3.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 2.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 0.9 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 2.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.7 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 2.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 1.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.8 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.9 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 2.2 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.9 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 2.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4