GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
RREB1 Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000124782.15	ras responsive element binding protein 1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
RREB1	hg19_v2_chr6_+_7108210_7108264	0.17	1.1e-02	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr16_+_447226 Show fit	12.63	ENST00000433358.1	NME4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NME/NM23 nucleoside diphosphate kinase 4
chrX_-_151903101 Show fit	11.75	ENST00000393900.3	MAGEA12 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	melanoma antigen family A, 12
chrX_-_151903184 Show fit	11.75	ENST00000357916.4 ENST00000393869.3	MAGEA12 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	melanoma antigen family A, 12
chr16_+_447209 Show fit	11.55	ENST00000382940.4 ENST00000219479.2	NME4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NME/NM23 nucleoside diphosphate kinase 4
chrX_+_151903207 Show fit	10.55	ENST00000370287.3	CSAG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chondrosarcoma associated gene 1
chrX_+_151867214 Show fit	9.03	ENST00000329342.5 ENST00000412733.1 ENST00000457643.1	MAGEA6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	melanoma antigen family A, 6
chrX_+_151903253 Show fit	9.00	ENST00000452779.2 ENST00000370291.2	CSAG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chondrosarcoma associated gene 1
chrX_-_151938171 Show fit	7.33	ENST00000393902.3 ENST00000417212.1 ENST00000370278.3	MAGEA3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	melanoma antigen family A, 3
chrX_-_151922340 Show fit	6.12	ENST00000370284.1 ENST00000543232.1 ENST00000393876.1 ENST00000393872.3	MAGEA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	melanoma antigen family A, 2
chr1_+_46668994 Show fit	5.81	ENST00000371980.3	LURAP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	leucine rich adaptor protein 1
chrX_+_151883090 Show fit	5.79	ENST00000370293.2 ENST00000423993.1 ENST00000447530.1 ENST00000458057.1 ENST00000331220.2 ENST00000422085.1 ENST00000453150.1 ENST00000409560.1	MAGEA2B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	melanoma antigen family A, 2B
chrX_+_151081351 Show fit	4.78	ENST00000276344.2	MAGEA4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	melanoma antigen family A, 4
chr6_+_151646800 Show fit	4.66	ENST00000354675.6	AKAP12 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	A kinase (PRKA) anchor protein 12
chr7_-_19157248 Show fit	4.64	ENST00000242261.5	TWIST1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	twist family bHLH transcription factor 1
chr8_+_144816303 Show fit	4.41	ENST00000533004.1	FAM83H-AS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FAM83H antisense RNA 1 (head to head)
chr19_-_6720686 Show fit	4.36	ENST00000245907.6	C3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	complement component 3
chr7_+_75932863 Show fit	4.26	ENST00000429938.1	HSPB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heat shock 27kDa protein 1
chr12_+_54447637 Show fit	4.26	ENST00000609810.1 ENST00000430889.2	HOXC4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit HOXC4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	homeobox C4 Homeobox protein Hox-C4
chrX_+_153813407 Show fit	4.09	ENST00000443287.2 ENST00000333128.3	CTAG1A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cancer/testis antigen 1A
chr10_+_17271266 Show fit	3.74	ENST00000224237.5	VIM Links Ensembl NCBI GeneCards UniProt NextProt Show fit	vimentin
chr11_+_71791693 Show fit	3.53	ENST00000289488.2 ENST00000447974.1	LRTOMT Links Ensembl NCBI GeneCards UniProt NextProt Show fit	leucine rich transmembrane and O-methyltransferase domain containing
chrX_-_153847522 Show fit	3.36	ENST00000328435.2 ENST00000359887.4	CTAG1B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cancer/testis antigen 1B
chrX_-_153881842 Show fit	3.36	ENST00000369585.3 ENST00000247306.4	CTAG2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cancer/testis antigen 2
chr11_+_69455855 Show fit	3.29	ENST00000227507.2 ENST00000536559.1	CCND1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin D1
chrX_-_151307020 Show fit	3.22	ENST00000370323.4 ENST00000244096.3 ENST00000427322.2	MAGEA10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	melanoma antigen family A, 10
chr17_-_39677971 Show fit	3.10	ENST00000393976.2	KRT15 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	keratin 15
chr12_+_96588279 Show fit	3.00	ENST00000552142.1	ELK3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ELK3, ETS-domain protein (SRF accessory protein 2)
chr11_+_86511569 Show fit	2.96	ENST00000441050.1	PRSS23 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protease, serine, 23
chr12_-_53074182 Show fit	2.89	ENST00000252244.3	KRT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	keratin 1
chr1_-_204380919 Show fit	2.82	ENST00000367188.4	PPP1R15B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 1, regulatory subunit 15B
chr4_+_74735102 Show fit	2.79	ENST00000395761.3	CXCL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr3_+_154797877 Show fit	2.74	ENST00000462745.1 ENST00000493237.1	MME Links Ensembl NCBI GeneCards UniProt NextProt Show fit	membrane metallo-endopeptidase
chr11_+_46402744 Show fit	2.72	ENST00000533952.1	MDK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	midkine (neurite growth-promoting factor 2)
chrX_+_102631844 Show fit	2.68	ENST00000372634.1 ENST00000299872.7	NGFRAP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nerve growth factor receptor (TNFRSF16) associated protein 1
chr12_-_56101647 Show fit	2.54	ENST00000347027.6 ENST00000257879.6 ENST00000257880.7 ENST00000394230.2 ENST00000394229.2	ITGA7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	integrin, alpha 7
chr4_+_123747979 Show fit	2.49	ENST00000608478.1	FGF2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	fibroblast growth factor 2 (basic)
chrX_-_148669116 Show fit	2.48	ENST00000243314.5	MAGEA9B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	melanoma antigen family A, 9B
chr9_-_21994597 Show fit	2.40	ENST00000579755.1	CDKN2A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase inhibitor 2A
chr3_+_154797428 Show fit	2.38	ENST00000460393.1	MME Links Ensembl NCBI GeneCards UniProt NextProt Show fit	membrane metallo-endopeptidase
chr2_+_46926326 Show fit	2.36	ENST00000394861.2	SOCS5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	suppressor of cytokine signaling 5
chrX_-_100604184 Show fit	2.36	ENST00000372902.3	TIMM8A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	translocase of inner mitochondrial membrane 8 homolog A (yeast)
chrX_+_148863584 Show fit	2.33	ENST00000439010.2 ENST00000298974.5 ENST00000522429.1 ENST00000519822.1	MAGEA9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	melanoma antigen family A, 9
chr9_-_13279563 Show fit	2.25	ENST00000541718.1	MPDZ Links Ensembl NCBI GeneCards UniProt NextProt Show fit	multiple PDZ domain protein
chr9_-_21994344 Show fit	2.25	ENST00000530628.2 ENST00000361570.3	CDKN2A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase inhibitor 2A
chr17_-_66453562 Show fit	2.25	ENST00000262139.5 ENST00000546360.1	WIPI1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	WD repeat domain, phosphoinositide interacting 1
chrX_+_17755563 Show fit	2.23	ENST00000380045.3 ENST00000380041.3 ENST00000380043.3 ENST00000398080.1	SCML1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sex comb on midleg-like 1 (Drosophila)
chr2_+_48757278 Show fit	2.19	ENST00000404752.1 ENST00000406226.1	STON1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	stonin 1
chr9_-_13279406 Show fit	2.19	ENST00000546205.1	MPDZ Links Ensembl NCBI GeneCards UniProt NextProt Show fit	multiple PDZ domain protein
chr8_+_28748099 Show fit	2.18	ENST00000519047.1	HMBOX1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	homeobox containing 1
chr19_-_42759300 Show fit	2.06	ENST00000222329.4	ERF Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Ets2 repressor factor
chr19_+_55477711 Show fit	2.04	ENST00000448584.2 ENST00000537859.1 ENST00000585500.1 ENST00000427260.2 ENST00000538819.1 ENST00000263437.6	NLRP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NLR family, pyrin domain containing 2
chr19_+_55476620 Show fit	2.03	ENST00000543010.1 ENST00000391721.4 ENST00000339757.7	NLRP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NLR family, pyrin domain containing 2
chr17_-_72864739 Show fit	2.03	ENST00000579893.1 ENST00000544854.1	FDXR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ferredoxin reductase
chr19_+_35609380 Show fit	2.00	ENST00000604621.1	FXYD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FXYD domain containing ion transport regulator 3
chr13_-_37494365 Show fit	1.96	ENST00000350148.5	SMAD9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SMAD family member 9
chr4_+_123747834 Show fit	1.95	ENST00000264498.3	FGF2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	fibroblast growth factor 2 (basic)
chr13_-_37494391 Show fit	1.94	ENST00000379826.4	SMAD9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SMAD family member 9
chr12_-_123849374 Show fit	1.91	ENST00000602398.1 ENST00000602750.1	SBNO1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	strawberry notch homolog 1 (Drosophila)
chr1_-_153538292 Show fit	1.86	ENST00000497140.1 ENST00000368708.3	S100A2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	S100 calcium binding protein A2
chr16_-_3285144 Show fit	1.85	ENST00000431561.3 ENST00000396870.4	ZNF200 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 200
chr19_-_3029011 Show fit	1.85	ENST00000590536.1 ENST00000587137.1 ENST00000455444.2 ENST00000262953.6	TLE2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr12_+_96588143 Show fit	1.85	ENST00000228741.3 ENST00000547249.1	ELK3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ELK3, ETS-domain protein (SRF accessory protein 2)
chr22_+_32750872 Show fit	1.83	ENST00000397468.1	RFPL3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ret finger protein-like 3
chr1_+_18958008 Show fit	1.78	ENST00000420770.2 ENST00000400661.3	PAX7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	paired box 7
chr11_+_46403303 Show fit	1.76	ENST00000407067.1 ENST00000395565.1	MDK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	midkine (neurite growth-promoting factor 2)
chr19_-_3025614 Show fit	1.76	ENST00000447365.2	TLE2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr12_+_54402790 Show fit	1.75	ENST00000040584.4	HOXC8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	homeobox C8
chr11_+_46403194 Show fit	1.71	ENST00000395569.4 ENST00000395566.4	MDK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	midkine (neurite growth-promoting factor 2)
chr3_-_55521323 Show fit	1.68	ENST00000264634.4	WNT5A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	wingless-type MMTV integration site family, member 5A
chr21_+_44073916 Show fit	1.64	ENST00000349112.3 ENST00000398224.3	PDE9A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphodiesterase 9A
chr9_-_13279589 Show fit	1.63	ENST00000319217.7	MPDZ Links Ensembl NCBI GeneCards UniProt NextProt Show fit	multiple PDZ domain protein
chr9_-_14314066 Show fit	1.61	ENST00000397575.3	NFIB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear factor I/B
chr9_-_14313893 Show fit	1.60	ENST00000380921.3 ENST00000380959.3	NFIB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear factor I/B
chr6_+_7541808 Show fit	1.55	ENST00000379802.3	DSP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	desmoplakin
chr1_+_244998602 Show fit	1.55	ENST00000411948.2	COX20 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	COX20 cytochrome C oxidase assembly factor
chr9_+_132427883 Show fit	1.52	ENST00000372469.4	PRRX2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	paired related homeobox 2
chr21_+_44073860 Show fit	1.51	ENST00000335512.4 ENST00000539837.1 ENST00000291539.6 ENST00000380328.2 ENST00000398232.3 ENST00000398234.3 ENST00000398236.3 ENST00000328862.6 ENST00000335440.6 ENST00000398225.3 ENST00000398229.3 ENST00000398227.3	PDE9A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphodiesterase 9A
chr22_-_46450024 Show fit	1.48	ENST00000396008.2 ENST00000333761.1	C22orf26 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 22 open reading frame 26
chr6_+_7541845 Show fit	1.48	ENST00000418664.2	DSP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	desmoplakin
chr16_-_4588469 Show fit	1.46	ENST00000588381.1 ENST00000563332.2	CDIP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cell death-inducing p53 target 1
chr16_-_31439735 Show fit	1.46	ENST00000287490.4	COX6A2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cytochrome c oxidase subunit VIa polypeptide 2
chr16_+_28889703 Show fit	1.45	ENST00000357084.3	ATP2A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr18_+_55102917 Show fit	1.44	ENST00000491143.2	ONECUT2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	one cut homeobox 2
chr16_+_28834303 Show fit	1.43	ENST00000340394.8 ENST00000325215.6 ENST00000395547.2 ENST00000336783.4 ENST00000382686.4 ENST00000564304.1	ATXN2L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ataxin 2-like
chr10_+_115438920 Show fit	1.42	ENST00000429617.1 ENST00000369331.4	CASP7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	caspase 7, apoptosis-related cysteine peptidase
chr1_+_154975110 Show fit	1.41	ENST00000535420.1 ENST00000368426.3	ZBTB7B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger and BTB domain containing 7B
chr1_-_113249948 Show fit	1.39	ENST00000339083.7 ENST00000369642.3	RHOC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ras homolog family member C
chr13_+_60971427 Show fit	1.39	ENST00000535286.1 ENST00000377881.2	TDRD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tudor domain containing 3
chr19_-_51456198 Show fit	1.39	ENST00000594846.1	KLK5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	kallikrein-related peptidase 5
chr16_+_28889801 Show fit	1.38	ENST00000395503.4	ATP2A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr13_-_74708372 Show fit	1.38	ENST00000377666.4	KLF12 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Kruppel-like factor 12
chr19_+_3366547 Show fit	1.38	ENST00000341919.3 ENST00000590282.1 ENST00000443272.2	NFIC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear factor I/C (CCAAT-binding transcription factor)
chr4_+_147560042 Show fit	1.34	ENST00000281321.3	POU4F2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	POU class 4 homeobox 2
chr7_+_114562172 Show fit	1.34	ENST00000393486.1 ENST00000257724.3	MDFIC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	MyoD family inhibitor domain containing
chr19_-_51456321 Show fit	1.33	ENST00000391809.2	KLK5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	kallikrein-related peptidase 5
chr12_+_16064258 Show fit	1.33	ENST00000524480.1 ENST00000531803.1 ENST00000532964.1	DERA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	deoxyribose-phosphate aldolase (putative)
chr21_-_47648665 Show fit	1.31	ENST00000450351.1 ENST00000522411.1 ENST00000356396.4 ENST00000397728.3 ENST00000457828.2	LSS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr1_-_113249734 Show fit	1.29	ENST00000484054.3 ENST00000369636.2 ENST00000369637.1 ENST00000285735.2 ENST00000369638.2	RHOC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ras homolog family member C
chr1_-_113249678 Show fit	1.29	ENST00000369633.2 ENST00000425265.2 ENST00000369632.2 ENST00000436685.2	RHOC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ras homolog family member C
chrX_-_131352152 Show fit	1.28	ENST00000342983.2	RAP2C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RAP2C, member of RAS oncogene family
chr1_-_17307173 Show fit	1.27	ENST00000438542.1 ENST00000375535.3	MFAP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	microfibrillar-associated protein 2
chr19_-_19051927 Show fit	1.26	ENST00000600077.1	HOMER3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	homer homolog 3 (Drosophila)
chr16_+_28834531 Show fit	1.25	ENST00000570200.1	ATXN2L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ataxin 2-like
chr7_-_24797032 Show fit	1.25	ENST00000409970.1 ENST00000409775.3	DFNA5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	deafness, autosomal dominant 5
chrX_+_119495934 Show fit	1.23	ENST00000218008.3 ENST00000361319.3 ENST00000539306.1	ATP1B4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase, Na+/K+ transporting, beta 4 polypeptide
chr2_+_105471969 Show fit	1.21	ENST00000361360.2	POU3F3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	POU class 3 homeobox 3
chr1_-_113392399 Show fit	1.21	ENST00000449572.2 ENST00000433505.1	RP11-426L16.8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RP11-426L16.8
chr11_+_111896320 Show fit	1.21	ENST00000531306.1 ENST00000537636.1	DLAT Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dihydrolipoamide S-acetyltransferase
chr15_+_63481668 Show fit	1.18	ENST00000321437.4 ENST00000559006.1 ENST00000448330.2	RAB8B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RAB8B, member RAS oncogene family
chr15_-_35088340 Show fit	1.18	ENST00000290378.4	ACTC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	actin, alpha, cardiac muscle 1
chr19_+_48867652 Show fit	1.18	ENST00000344846.2	SYNGR4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	synaptogyrin 4
chr12_-_131323754 Show fit	1.17	ENST00000261653.6	STX2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	syntaxin 2
chr5_+_150591678 Show fit	1.17	ENST00000523466.1	GM2A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	GM2 ganglioside activator
chr10_+_13628933 Show fit	1.16	ENST00000417658.1 ENST00000320054.4	PRPF18 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pre-mRNA processing factor 18
chr19_+_51358166 Show fit	1.14	ENST00000601503.1 ENST00000326003.2 ENST00000597286.1 ENST00000597483.1	KLK3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	kallikrein-related peptidase 3
chr15_-_43513187 Show fit	1.14	ENST00000540029.1 ENST00000441366.2	EPB42 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	erythrocyte membrane protein band 4.2
chr14_+_74353320 Show fit	1.13	ENST00000540593.1 ENST00000555730.1	ZNF410 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 410
chr19_+_51358191 Show fit	1.12	ENST00000593997.1 ENST00000595952.1 ENST00000360617.3 ENST00000598145.1	KLK3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	kallikrein-related peptidase 3
chr19_-_15560730 Show fit	1.11	ENST00000389282.4 ENST00000263381.7	WIZ Links Ensembl NCBI GeneCards UniProt NextProt Show fit	widely interspaced zinc finger motifs
chr6_+_7107830 Show fit	1.11	ENST00000379933.3	RREB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ras responsive element binding protein 1
chr19_-_51456344 Show fit	1.11	ENST00000336334.3 ENST00000593428.1	KLK5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	kallikrein-related peptidase 5
chr17_+_77751931 Show fit	1.10	ENST00000310942.4 ENST00000269399.5	CBX2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromobox homolog 2
chr13_-_76056250 Show fit	1.08	ENST00000377636.3 ENST00000431480.2 ENST00000377625.2 ENST00000425511.1	TBC1D4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TBC1 domain family, member 4
chr16_+_69599861 Show fit	1.07	ENST00000354436.2	NFAT5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear factor of activated T-cells 5, tonicity-responsive
chr19_+_36157715 Show fit	1.06	ENST00000379013.2 ENST00000222275.2	UPK1A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	uroplakin 1A
chr16_+_1728305 Show fit	1.06	ENST00000569765.1	HN1L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	hematological and neurological expressed 1-like
chr3_+_186435137 Show fit	1.06	ENST00000447445.1	KNG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	kininogen 1
chr17_-_58156273 Show fit	1.06	ENST00000593228.1 ENST00000585976.1 ENST00000593097.1 ENST00000184956.6	HEATR6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	HEAT repeat containing 6
chr2_+_192542850 Show fit	1.05	ENST00000410026.2	NABP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nucleic acid binding protein 1
chr8_+_32406137 Show fit	1.03	ENST00000521670.1	NRG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neuregulin 1
chr6_+_168227611 Show fit	1.02	ENST00000344191.4 ENST00000351017.4 ENST00000392108.3 ENST00000366806.2 ENST00000392112.1 ENST00000400824.4 ENST00000447894.2 ENST00000400822.3	MLLT4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
chr12_-_56120865 Show fit	1.02	ENST00000548898.1 ENST00000552067.1	CD63 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CD63 molecule
chr18_+_9334786 Show fit	1.00	ENST00000581641.1	TWSG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	twisted gastrulation BMP signaling modulator 1
chr11_-_74109422 Show fit	0.99	ENST00000298198.4	PGM2L1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphoglucomutase 2-like 1
chr17_+_79373540 Show fit	0.97	ENST00000307745.7	RP11-1055B8.7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	BAH and coiled-coil domain-containing protein 1
chr12_-_44152551 Show fit	0.97	ENST00000416848.2 ENST00000550784.1 ENST00000547156.1 ENST00000549868.1 ENST00000553166.1 ENST00000551923.1 ENST00000431332.3 ENST00000344862.5	PUS7L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pseudouridylate synthase 7 homolog (S. cerevisiae)-like
chr12_-_131323719 Show fit	0.97	ENST00000392373.2	STX2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	syntaxin 2
chr4_-_96470350 Show fit	0.96	ENST00000504962.1 ENST00000453304.1 ENST00000506749.1	UNC5C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	unc-5 homolog C (C. elegans)
chr20_+_48599506 Show fit	0.95	ENST00000244050.2	SNAI1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	snail family zinc finger 1
chr19_-_51222707 Show fit	0.95	ENST00000391814.1	SHANK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SH3 and multiple ankyrin repeat domains 1
chr10_-_75415825 Show fit	0.95	ENST00000394810.2	SYNPO2L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	synaptopodin 2-like
chr12_-_56120838 Show fit	0.94	ENST00000548160.1	CD63 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CD63 molecule
chr19_+_7828035 Show fit	0.94	ENST00000327325.5 ENST00000394122.2 ENST00000248228.4 ENST00000334806.5 ENST00000359059.5 ENST00000357361.2 ENST00000596363.1 ENST00000595751.1 ENST00000596707.1 ENST00000597522.1 ENST00000595496.1	CLEC4M Links Ensembl NCBI GeneCards UniProt NextProt Show fit	C-type lectin domain family 4, member M
chr9_+_131174024 Show fit	0.92	ENST00000420034.1 ENST00000372842.1	CERCAM Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cerebral endothelial cell adhesion molecule
chr16_+_68771128 Show fit	0.92	ENST00000261769.5 ENST00000422392.2	CDH1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cadherin 1, type 1, E-cadherin (epithelial)
chr9_-_14722715 Show fit	0.91	ENST00000380911.3	CER1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cerberus 1, DAN family BMP antagonist
chr2_+_85843252 Show fit	0.90	ENST00000409025.1 ENST00000409470.1 ENST00000323701.6 ENST00000409766.3	USP39 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin specific peptidase 39
chr2_-_54087066 Show fit	0.89	ENST00000394705.2 ENST00000352846.3 ENST00000406625.2	GPR75 Links Ensembl NCBI GeneCards UniProt NextProt Show fit GPR75-ASB3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit ASB3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	G protein-coupled receptor 75 GPR75-ASB3 readthrough Ankyrin repeat and SOCS box protein 3
chr1_+_154975258 Show fit	0.89	ENST00000417934.2	ZBTB7B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger and BTB domain containing 7B
chr17_+_41177220 Show fit	0.89	ENST00000587250.2 ENST00000544533.1	RND2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho family GTPase 2
chr1_-_228604328 Show fit	0.89	ENST00000355586.4 ENST00000366698.2 ENST00000520264.1 ENST00000479800.1 ENST00000295033.3	TRIM17 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tripartite motif containing 17
chr4_+_190992087 Show fit	0.88	ENST00000553598.1	DUX4L7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	double homeobox 4 like 7
chr2_+_223289208 Show fit	0.88	ENST00000321276.7	SGPP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sphingosine-1-phosphate phosphatase 2
chr1_+_18957500 Show fit	0.86	ENST00000375375.3	PAX7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	paired box 7
chr2_-_220108309 Show fit	0.86	ENST00000409640.1	GLB1L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	galactosidase, beta 1-like
chr18_+_9334755 Show fit	0.86	ENST00000262120.5	TWSG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	twisted gastrulation BMP signaling modulator 1
chr11_-_89224488 Show fit	0.85	ENST00000534731.1 ENST00000527626.1	NOX4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NADPH oxidase 4
chr19_-_51192661 Show fit	0.85	ENST00000391813.1	SHANK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SH3 and multiple ankyrin repeat domains 1
chr1_+_157963063 Show fit	0.83	ENST00000360089.4 ENST00000368173.3 ENST00000392272.2	KIRREL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	kin of IRRE like (Drosophila)
chrX_+_149737046 Show fit	0.82	ENST00000370396.2 ENST00000542741.1 ENST00000543350.1 ENST00000424519.1 ENST00000413012.2	MTM1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myotubularin 1
chr8_+_28748765 Show fit	0.82	ENST00000355231.5	HMBOX1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	homeobox containing 1
chr1_-_201346761 Show fit	0.80	ENST00000455702.1 ENST00000422165.1 ENST00000367318.5 ENST00000367320.2 ENST00000438742.1 ENST00000412633.1 ENST00000458432.2 ENST00000421663.2 ENST00000367322.1 ENST00000509001.1	TNNT2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	troponin T type 2 (cardiac)
chr1_-_156470556 Show fit	0.80	ENST00000489057.1 ENST00000348159.4	MEF2D Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myocyte enhancer factor 2D
chr8_+_73449625 Show fit	0.80	ENST00000523207.1	KCNB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	potassium voltage-gated channel, Shab-related subfamily, member 2
chr5_+_151151504 Show fit	0.79	ENST00000356245.3 ENST00000507878.2	G3BP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	GTPase activating protein (SH3 domain) binding protein 1
chr18_+_33877654 Show fit	0.79	ENST00000257209.4 ENST00000445677.1 ENST00000590592.1 ENST00000359247.4	FHOD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	formin homology 2 domain containing 3
chr17_-_46703826 Show fit	0.76	ENST00000550387.1 ENST00000311177.5	HOXB9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	homeobox B9
chr19_+_44085189 Show fit	0.75	ENST00000562365.2	PINLYP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr20_+_57875658 Show fit	0.75	ENST00000371025.3	EDN3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	endothelin 3
chr7_+_91570165 Show fit	0.75	ENST00000356239.3 ENST00000359028.2 ENST00000358100.2	AKAP9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	A kinase (PRKA) anchor protein 9
chr16_+_67198683 Show fit	0.75	ENST00000517685.1 ENST00000521374.1 ENST00000584272.1	HSF4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heat shock transcription factor 4
chr7_-_154794763 Show fit	0.74	ENST00000404141.1	PAXIP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	PAX interacting (with transcription-activation domain) protein 1
chr3_+_192958914 Show fit	0.73	ENST00000264735.2 ENST00000602513.1	HRASLS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	HRAS-like suppressor
chr7_+_39125365 Show fit	0.73	ENST00000559001.1 ENST00000464276.2	POU6F2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	POU class 6 homeobox 2
chr17_-_62658186 Show fit	0.73	ENST00000262435.9	SMURF2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SMAD specific E3 ubiquitin protein ligase 2
chr3_+_8775466 Show fit	0.73	ENST00000343849.2 ENST00000397368.2	CAV3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	caveolin 3
chr18_+_77160282 Show fit	0.72	ENST00000318065.5 ENST00000545796.1 ENST00000592223.1 ENST00000329101.4 ENST00000586434.1	NFATC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr17_+_35849937 Show fit	0.72	ENST00000394389.4	DUSP14 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dual specificity phosphatase 14
chr12_-_6716569 Show fit	0.72	ENST00000544040.1 ENST00000545942.1	CHD4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromodomain helicase DNA binding protein 4
chr8_+_32406179 Show fit	0.71	ENST00000405005.3	NRG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neuregulin 1
chr5_+_151151471 Show fit	0.71	ENST00000394123.3 ENST00000543466.1	G3BP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	GTPase activating protein (SH3 domain) binding protein 1
chr20_-_25062767 Show fit	0.70	ENST00000429762.3 ENST00000444511.2 ENST00000376707.3	VSX1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	visual system homeobox 1
chr17_-_1733114 Show fit	0.68	ENST00000305513.7	SMYD4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SET and MYND domain containing 4
chr7_-_38398721 Show fit	0.68	ENST00000390346.2	TRGV3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	T cell receptor gamma variable 3
chr4_+_190992387 Show fit	0.68	ENST00000554906.2 ENST00000553820.2	DUX4L7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	double homeobox 4 like 7
chr1_-_161193349 Show fit	0.68	ENST00000469730.2 ENST00000463273.1 ENST00000464492.1 ENST00000367990.3 ENST00000470459.2 ENST00000468465.1 ENST00000463812.1	APOA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	apolipoprotein A-II
chr19_+_44084696 Show fit	0.67	ENST00000562255.1 ENST00000569031.2	PINLYP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr16_+_21169976 Show fit	0.67	ENST00000572258.1 ENST00000261388.3 ENST00000451578.2 ENST00000572599.1 ENST00000577162.1	TMEM159 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 159
chr3_+_141205852 Show fit	0.67	ENST00000286364.3 ENST00000452898.1	RASA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RAS p21 protein activator 2
chr2_+_28618532 Show fit	0.67	ENST00000545753.1	FOSL2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FOS-like antigen 2
chrX_+_53078273 Show fit	0.66	ENST00000332582.4	GPR173 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	G protein-coupled receptor 173
chr4_+_164265035 Show fit	0.66	ENST00000338566.3	NPY5R Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neuropeptide Y receptor Y5
chr10_-_35379241 Show fit	0.66	ENST00000374748.1 ENST00000374749.3	CUL2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cullin 2
chr7_-_14028488 Show fit	0.66	ENST00000405358.4	ETV1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ets variant 1
chr11_-_96239990 Show fit	0.65	ENST00000511243.2	JRKL-AS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	JRKL antisense RNA 1
chr6_-_35480705 Show fit	0.64	ENST00000229771.6	TULP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tubby like protein 1
chr5_-_35195338 Show fit	0.64	ENST00000509839.1	PRLR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	prolactin receptor
chr1_-_156470515 Show fit	0.64	ENST00000340875.5 ENST00000368240.2 ENST00000353795.3	MEF2D Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myocyte enhancer factor 2D
chr10_-_121356518 Show fit	0.63	ENST00000369092.4	TIAL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TIA1 cytotoxic granule-associated RNA binding protein-like 1
chr7_-_154794621 Show fit	0.63	ENST00000419436.1 ENST00000397192.1	PAXIP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	PAX interacting (with transcription-activation domain) protein 1

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.0	24.2	GO:0006228	UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
1.5	4.6	GO:2000276	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
1.5	4.4	GO:0002894	positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
1.3	5.1	GO:0071492	cellular response to UV-A(GO:0071492)
1.1	4.3	GO:0099640	axo-dendritic protein transport(GO:0099640)
1.0	6.2	GO:0030421	defecation(GO:0030421)
0.9	2.8	GO:0031446	regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.7	2.2	GO:0048203	vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.7	4.0	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
0.7	2.6	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.6	3.8	GO:0002760	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.6	4.4	GO:2000546	positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.6	1.8	GO:0050894	determination of affect(GO:0050894)
0.6	2.3	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.6	1.7	GO:1904933	cardiac right atrium morphogenesis(GO:0003213) negative regulation of melanin biosynthetic process(GO:0048022) positive regulation of anagen(GO:0051885) mediolateral intercalation(GO:0060031) cervix development(GO:0060067) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775) negative regulation of secondary metabolite biosynthetic process(GO:1900377) regulation of cell proliferation in midbrain(GO:1904933)
0.5	3.3	GO:0070141	response to UV-A(GO:0070141)
0.5	1.9	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.5	3.2	GO:0021730	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.5	2.3	GO:0002778	antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778)
0.4	1.3	GO:0061074	regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
0.4	3.0	GO:0071896	protein localization to adherens junction(GO:0071896)
0.4	4.6	GO:0035986	senescence-associated heterochromatin focus assembly(GO:0035986)
0.4	1.2	GO:0051461	positive regulation of corticotropin secretion(GO:0051461)
0.4	2.4	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.3	3.7	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.3	0.7	GO:0060769	positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769)
0.3	2.3	GO:0021842	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.3	4.7	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.3	5.4	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.3	2.8	GO:0006983	ER overload response(GO:0006983)
0.3	6.5	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.3	1.7	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.3	2.0	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
0.3	1.1	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.3	0.8	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.3	1.1	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.3	1.0	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
0.3	3.5	GO:0060117	auditory receptor cell development(GO:0060117)
0.2	0.7	GO:0048867	stem cell fate determination(GO:0048867)
0.2	1.2	GO:0072240	thick ascending limb development(GO:0072023) DCT cell differentiation(GO:0072069) metanephric thick ascending limb development(GO:0072233) metanephric DCT cell differentiation(GO:0072240)
0.2	0.9	GO:1900175	regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175)
0.2	0.7	GO:0060621	regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
0.2	2.9	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.2	2.7	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.2	1.0	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.2	0.8	GO:0032972	regulation of muscle filament sliding speed(GO:0032972)
0.2	1.2	GO:0072553	terminal button organization(GO:0072553)
0.2	1.2	GO:0090131	mesenchyme migration(GO:0090131)
0.2	3.3	GO:0046069	cGMP catabolic process(GO:0046069)
0.2	1.0	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.2	1.0	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.2	0.9	GO:0046968	peptide antigen transport(GO:0046968)
0.2	0.7	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.2	0.7	GO:0035995	detection of muscle stretch(GO:0035995)
0.2	1.4	GO:0072733	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.2	0.7	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.2	1.1	GO:0010571	positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.2	0.7	GO:0097211	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.2	0.3	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.2	2.0	GO:0035826	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1	0.7	GO:0051661	maintenance of centrosome location(GO:0051661)
0.1	1.2	GO:0006689	ganglioside catabolic process(GO:0006689)
0.1	1.3	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
0.1	1.0	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.1	0.4	GO:0051102	DNA ligation involved in DNA recombination(GO:0051102)
0.1	0.9	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.1	0.4	GO:0006059	hexitol metabolic process(GO:0006059)
0.1	2.8	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023)
0.1	0.2	GO:0043385	mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.1	1.5	GO:0097034	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1	0.8	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.1	4.1	GO:0050718	positive regulation of interleukin-1 beta secretion(GO:0050718)
0.1	0.3	GO:0060370	susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1	1.1	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500) protein localization to photoreceptor outer segment(GO:1903546)
0.1	0.7	GO:0002865	negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
0.1	4.1	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1	2.1	GO:0099500	synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1	2.0	GO:1901663	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1	0.6	GO:0038161	prolactin signaling pathway(GO:0038161)
0.1	1.4	GO:0007512	adult heart development(GO:0007512)
0.1	2.2	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.1	0.6	GO:0048549	positive regulation of pinocytosis(GO:0048549)
0.1	0.3	GO:1904847	cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.1	0.3	GO:0002028	regulation of sodium ion transport(GO:0002028)
0.1	0.5	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
0.1	0.4	GO:0034729	histone H3-K79 methylation(GO:0034729)
0.1	1.1	GO:0043249	erythrocyte maturation(GO:0043249)
0.1	0.4	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1	2.4	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1	0.9	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.1	0.3	GO:0071030	nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.1	1.6	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1	0.4	GO:1900264	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1	0.5	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.1	1.0	GO:0019388	galactose catabolic process(GO:0019388)
0.1	0.6	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1	0.3	GO:0060010	Sertoli cell fate commitment(GO:0060010)
0.1	1.3	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.1	3.0	GO:0032212	positive regulation of telomere maintenance via telomerase(GO:0032212)
0.1	1.9	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1	1.5	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1	0.9	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
0.1	0.2	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.1	0.1	GO:0071284	cellular response to lead ion(GO:0071284)
0.1	0.4	GO:1903385	regulation of homophilic cell adhesion(GO:1903385)
0.1	0.4	GO:1903232	melanosome assembly(GO:1903232)
0.1	0.1	GO:1904048	regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.1	0.5	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.1	0.8	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.1	0.9	GO:0034311	sphingosine metabolic process(GO:0006670) diol metabolic process(GO:0034311)
0.1	0.2	GO:2000661	positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.1	0.2	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0	2.5	GO:0035987	endodermal cell differentiation(GO:0035987)
0.0	0.7	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.1	GO:0034971	histone H3-R17 methylation(GO:0034971)
0.0	0.5	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.3	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.0	1.9	GO:0043542	endothelial cell migration(GO:0043542)
0.0	1.1	GO:0000470	maturation of LSU-rRNA(GO:0000470)
0.0	0.6	GO:0034162	toll-like receptor 9 signaling pathway(GO:0034162)
0.0	0.5	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0	1.8	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	4.1	GO:0070268	cornification(GO:0070268)
0.0	0.2	GO:2000773	negative regulation of cellular senescence(GO:2000773)
0.0	1.1	GO:0042311	vasodilation(GO:0042311)
0.0	0.7	GO:0003334	keratinocyte development(GO:0003334)
0.0	2.0	GO:2000649	regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0	0.4	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.0	0.5	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.5	GO:0035641	locomotory exploration behavior(GO:0035641)
0.0	1.7	GO:0050434	positive regulation of viral transcription(GO:0050434)
0.0	1.4	GO:0042475	odontogenesis of dentin-containing tooth(GO:0042475)
0.0	0.7	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.5	GO:0031424	keratinization(GO:0031424)
0.0	0.3	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.0	0.9	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.4	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.0	0.2	GO:0060285	cilium-dependent cell motility(GO:0060285)
0.0	0.6	GO:0017145	stem cell division(GO:0017145)
0.0	1.5	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	4.3	GO:0051216	cartilage development(GO:0051216)
0.0	4.0	GO:0090090	negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0	0.8	GO:0072661	protein targeting to plasma membrane(GO:0072661)
0.0	0.7	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	4.0	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0	0.1	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.0	0.6	GO:0060113	inner ear receptor cell differentiation(GO:0060113)
0.0	0.9	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
0.0	0.1	GO:0055129	proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0	1.7	GO:0048705	skeletal system morphogenesis(GO:0048705)
0.0	0.0	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.0	0.3	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.8	GO:0007588	excretion(GO:0007588)
0.0	0.4	GO:0051930	regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0	0.3	GO:0007194	negative regulation of adenylate cyclase activity(GO:0007194)
0.0	0.5	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0	0.4	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	3.8	GO:0097209	epidermal lamellar body(GO:0097209)
0.4	4.6	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.4	1.5	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.3	6.1	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.3	1.2	GO:0005889	hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.3	26.5	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.3	3.2	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.3	1.1	GO:0070876	SOSS complex(GO:0070876)
0.2	3.7	GO:0005916	fascia adherens(GO:0005916)
0.2	1.5	GO:0098560	cytoplasmic side of late endosome membrane(GO:0098560)
0.2	1.2	GO:0042643	actomyosin, actin portion(GO:0042643)
0.2	0.6	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.2	3.9	GO:0071141	SMAD protein complex(GO:0071141)
0.2	2.8	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.2	2.8	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.2	2.0	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.1	1.2	GO:0051286	cell tip(GO:0051286)
0.1	0.8	GO:1990584	cardiac Troponin complex(GO:1990584)
0.1	0.7	GO:0030891	VCB complex(GO:0030891)
0.1	0.9	GO:0016342	catenin complex(GO:0016342)
0.1	1.4	GO:0044666	MLL3/4 complex(GO:0044666)
0.1	4.0	GO:0032420	stereocilium(GO:0032420)
0.1	1.8	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	1.1	GO:0042788	polysomal ribosome(GO:0042788)
0.1	0.4	GO:0031085	BLOC-3 complex(GO:0031085)
0.1	1.5	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.1	4.3	GO:1904115	axon cytoplasm(GO:1904115)
0.1	0.3	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.1	2.2	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.1	0.8	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.1	11.3	GO:0005882	intermediate filament(GO:0005882)
0.1	3.0	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.1	0.3	GO:0071020	post-spliceosomal complex(GO:0071020)
0.1	1.1	GO:0035102	PRC1 complex(GO:0035102)
0.1	2.1	GO:0030673	axolemma(GO:0030673)
0.1	0.4	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.1	0.4	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.1	1.2	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1	1.3	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.1	2.7	GO:0008305	integrin complex(GO:0008305)
0.1	3.5	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1	6.8	GO:0042641	actomyosin(GO:0042641)
0.0	0.8	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.7	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.0	0.4	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	1.9	GO:0045178	basal part of cell(GO:0045178)
0.0	4.0	GO:0005903	brush border(GO:0005903)
0.0	3.7	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	2.2	GO:0031201	SNARE complex(GO:0031201)
0.0	2.5	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.9	GO:0002080	acrosomal membrane(GO:0002080)
0.0	2.0	GO:0044291	cell-cell contact zone(GO:0044291)
0.0	3.5	GO:0000784	nuclear chromosome, telomeric region(GO:0000784)
0.0	1.1	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	1.0	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.8	GO:0005865	striated muscle thin filament(GO:0005865)
0.0	3.1	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.3	GO:0042588	zymogen granule(GO:0042588)
0.0	1.8	GO:0005811	lipid particle(GO:0005811)
0.0	1.9	GO:0035580	specific granule lumen(GO:0035580)
0.0	0.1	GO:0044326	dendritic spine neck(GO:0044326)
0.0	10.4	GO:0005925	focal adhesion(GO:0005925)
0.0	6.9	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.4	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.3	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	0.4	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.2	GO:0005858	axonemal dynein complex(GO:0005858)
0.0	2.0	GO:0016605	PML body(GO:0016605)
0.0	0.6	GO:0031904	endosome lumen(GO:0031904)
0.0	0.7	GO:0005801	cis-Golgi network(GO:0005801)
0.0	1.8	GO:0101002	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0	1.8	GO:0031674	I band(GO:0031674)
0.0	1.5	GO:0001650	fibrillar center(GO:0001650)
0.0	0.2	GO:0000781	chromosome, telomeric region(GO:0000781)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.7	24.2	GO:1901612	cardiolipin binding(GO:1901612)
1.6	4.8	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
1.4	4.3	GO:0008426	protein kinase C inhibitor activity(GO:0008426)
1.4	4.1	GO:0032090	Pyrin domain binding(GO:0032090)
0.7	2.0	GO:0015039	ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.6	3.7	GO:1990254	keratin filament binding(GO:1990254)
0.6	7.3	GO:0089720	caspase binding(GO:0089720)
0.6	1.8	GO:0031877	somatostatin receptor binding(GO:0031877)
0.6	1.7	GO:0004139	deoxyribose-phosphate aldolase activity(GO:0004139)
0.5	1.5	GO:0016418	S-acetyltransferase activity(GO:0016418)
0.5	3.5	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
0.4	1.1	GO:0070984	SET domain binding(GO:0070984)
0.3	3.0	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.3	3.0	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.3	4.7	GO:0008179	adenylate cyclase binding(GO:0008179)
0.3	3.9	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.3	4.6	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2	3.3	GO:0030280	structural constituent of epidermis(GO:0030280)
0.2	2.3	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.2	5.5	GO:0071837	HMG box domain binding(GO:0071837)
0.2	0.7	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.2	1.0	GO:0031708	endothelin B receptor binding(GO:0031708)
0.2	0.9	GO:0004692	cGMP-dependent protein kinase activity(GO:0004692)
0.2	2.8	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.2	0.7	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.2	1.0	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.2	4.7	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	1.2	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.1	3.3	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1	1.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1	0.9	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.1	0.5	GO:0005502	11-cis retinal binding(GO:0005502)
0.1	0.9	GO:0016015	morphogen activity(GO:0016015)
0.1	0.6	GO:0004925	prolactin receptor activity(GO:0004925)
0.1	1.9	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.1	3.3	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1	1.2	GO:0030911	TPR domain binding(GO:0030911)
0.1	0.8	GO:0019215	intermediate filament binding(GO:0019215)
0.1	0.9	GO:0004565	beta-galactosidase activity(GO:0004565)
0.1	4.9	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.1	0.8	GO:0030172	troponin C binding(GO:0030172)
0.1	0.5	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1	2.8	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.1	1.3	GO:0030957	Tat protein binding(GO:0030957)
0.1	3.3	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1	0.4	GO:0004335	galactokinase activity(GO:0004335)
0.1	0.7	GO:0071253	connexin binding(GO:0071253)
0.1	2.2	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1	1.7	GO:0048018	receptor agonist activity(GO:0048018)
0.1	0.3	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
0.1	0.5	GO:0043813	phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.1	7.1	GO:0070491	repressing transcription factor binding(GO:0070491)
0.1	0.7	GO:0001225	RNA polymerase II transcription coactivator binding(GO:0001225)
0.1	0.2	GO:0098770	FBXO family protein binding(GO:0098770)
0.1	0.3	GO:0004803	transposase activity(GO:0004803)
0.1	0.5	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.1	0.2	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.1	0.4	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.1	0.4	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1	0.9	GO:0045295	gamma-catenin binding(GO:0045295)
0.1	0.9	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.1	1.4	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.1	1.0	GO:0016866	intramolecular transferase activity(GO:0016866)
0.1	1.9	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.1	1.5	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.9	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	1.0	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	1.4	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.7	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	2.1	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	5.1	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.2	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.3	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.7	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	2.0	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.2	GO:0004909	interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0	0.4	GO:0003910	DNA ligase (ATP) activity(GO:0003910)
0.0	2.0	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.3	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.0	6.8	GO:0008201	heparin binding(GO:0008201)
0.0	13.9	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0	9.0	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	0.7	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	1.9	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.4	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.4	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.3	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.5	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	2.8	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	6.2	GO:0003714	transcription corepressor activity(GO:0003714)
0.0	0.1	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0	6.6	GO:0008022	protein C-terminus binding(GO:0008022)
0.0	0.5	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.2	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	1.5	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.0	0.4	GO:0005522	profilin binding(GO:0005522)
0.0	6.6	GO:0003924	GTPase activity(GO:0003924)
0.0	0.4	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.7	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.2	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.0	0.7	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.6	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.5	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.9	GO:0097110	scaffold protein binding(GO:0097110)
0.0	0.6	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0	0.7	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	0.4	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	1.3	GO:0001047	core promoter binding(GO:0001047)
0.0	0.2	GO:0008391	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0	0.1	GO:0004955	prostaglandin receptor activity(GO:0004955)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	8.0	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2	3.9	PID ALK2 PATHWAY	ALK2 signaling events
0.2	4.4	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.1	7.2	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.1	4.0	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.1	4.9	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.1	7.0	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	4.6	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.1	2.5	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.1	2.6	PID NECTIN PATHWAY	Nectin adhesion pathway
0.1	0.8	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.1	2.8	PID IL23 PATHWAY	IL23-mediated signaling events
0.1	3.7	PID AURORA B PATHWAY	Aurora B signaling
0.1	1.7	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	3.9	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	1.9	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	1.4	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	1.1	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.7	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	1.1	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	4.5	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	2.5	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.7	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	2.2	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	0.4	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.3	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	1.4	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.9	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	2.0	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	1.0	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	1.6	PID BMP PATHWAY	BMP receptor signaling
0.0	1.4	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	1.1	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	1.3	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.8	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	1.0	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.6	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.4	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.3	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.4	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.7	PID NOTCH PATHWAY	Notch signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	24.2	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.4	4.7	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.2	4.6	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2	4.4	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.2	5.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2	3.5	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.1	2.8	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	0.1	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	4.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.1	3.2	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	1.6	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	2.3	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	2.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	0.8	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	3.6	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	2.1	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	0.9	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.6	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	1.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	1.6	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	2.4	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.7	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.4	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	1.2	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.6	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.7	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	2.2	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	1.4	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.4	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	1.6	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	1.8	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.9	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism
0.0	0.5	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	2.2	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.4	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.4	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.3	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.9	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	1.0	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	2.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.7	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	1.7	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.5	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.8	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.5	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.3	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4