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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for RUNX1_RUNX2

Z-value: 2.28

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Transcription factors associated with RUNX1_RUNX2

Gene Symbol Gene ID Gene Info
RUNX1
ENSG00000159216.14 RUNX family transcription factor 1
RUNX2
ENSG00000124813.16 RUNX family transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RUNX1hg19_v2_chr21_-_36260980_362610110.413.9e-10Click!
RUNX2hg19_v2_chr6_+_45389893_45389914,
hg19_v2_chr6_+_45296391_45296464		0.384.3e-09Click!

Activity profile of RUNX1_RUNX2 motif

Sorted Z-values of RUNX1_RUNX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_29641084 64.51 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr16_+_85942594 62.65 ENST00000566369.1
IRF8
interferon regulatory factor 8
chr17_-_29641104 59.20 ENST00000577894.1
ENST00000330927.4
EVI2B
ecotropic viral integration site 2B
chr2_+_90077680 51.11 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr22_+_23241661 50.88 ENST00000390322.2
IGLJ2
immunoglobulin lambda joining 2
chrX_-_106960285 45.26 ENST00000503515.1
ENST00000372397.2
TSC22D3
TSC22 domain family, member 3
chr8_-_134072593 44.33 ENST00000427060.2
SLA
Src-like-adaptor
chr2_-_89442621 43.33 ENST00000492167.1
IGKV3-20
immunoglobulin kappa variable 3-20
chr1_+_198608146 43.21 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
PTPRC
protein tyrosine phosphatase, receptor type, C
chr11_-_58345569 34.84 ENST00000528954.1
ENST00000528489.1
LPXN
leupaxin
chr4_-_84035868 33.23 ENST00000426923.2
ENST00000509973.1
PLAC8
placenta-specific 8
chr4_-_84035905 32.90 ENST00000311507.4
PLAC8
placenta-specific 8
chr1_+_209929377 32.63 ENST00000400959.3
ENST00000367025.3
TRAF3IP3
TRAF3 interacting protein 3
chr16_+_23847339 32.05 ENST00000303531.7
PRKCB
protein kinase C, beta
chr22_+_23247030 29.89 ENST00000390324.2
IGLJ3
immunoglobulin lambda joining 3
chr11_+_121447469 29.69 ENST00000532694.1
ENST00000534286.1
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr16_+_23847267 29.29 ENST00000321728.7
PRKCB
protein kinase C, beta
chr12_-_53594227 28.42 ENST00000550743.2
ITGB7
integrin, beta 7
chr1_+_209929494 28.17 ENST00000367026.3
TRAF3IP3
TRAF3 interacting protein 3
chr14_+_100531615 27.20 ENST00000392920.3
EVL
Enah/Vasp-like
chr16_+_56965960 27.14 ENST00000439977.2
ENST00000344114.4
ENST00000300302.5
ENST00000379792.2
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr6_-_33048483 27.01 ENST00000419277.1
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr16_+_30194916 26.67 ENST00000570045.1
ENST00000565497.1
ENST00000570244.1
CORO1A
coronin, actin binding protein, 1A
chr8_+_27168988 26.50 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
PTK2B
protein tyrosine kinase 2 beta
chr5_-_39219705 26.32 ENST00000351578.6
FYB
FYN binding protein
chr4_-_57524061 25.68 ENST00000508121.1
HOPX
HOP homeobox
chr14_-_106092403 25.13 ENST00000390543.2
IGHG4
immunoglobulin heavy constant gamma 4 (G4m marker)
chr11_+_1874200 24.69 ENST00000311604.3
LSP1
lymphocyte-specific protein 1
chr5_-_39203093 24.55 ENST00000515010.1
FYB
FYN binding protein
chr16_+_226658 23.70 ENST00000320868.5
ENST00000397797.1
HBA1
hemoglobin, alpha 1
chr1_-_25291475 23.35 ENST00000338888.3
ENST00000399916.1
RUNX3
runt-related transcription factor 3
chr17_-_34417479 22.10 ENST00000225245.5
CCL3
chemokine (C-C motif) ligand 3
chr5_-_39219641 21.74 ENST00000509072.1
ENST00000504542.1
ENST00000505428.1
ENST00000506557.1
FYB
FYN binding protein
chr2_-_158300556 21.57 ENST00000264192.3
CYTIP
cytohesin 1 interacting protein
chr19_-_36399149 21.52 ENST00000585901.2
ENST00000544690.2
ENST00000424586.3
ENST00000262629.4
ENST00000589517.1
TYROBP
TYRO protein tyrosine kinase binding protein
chr17_-_34625719 21.51 ENST00000422211.2
ENST00000542124.1
CCL3L1
chemokine (C-C motif) ligand 3-like 1
chr12_-_112819896 21.50 ENST00000377560.5
ENST00000430131.2
ENST00000550722.1
ENST00000550724.1
HECTD4
HECT domain containing E3 ubiquitin protein ligase 4
chr14_-_60097524 21.29 ENST00000342503.4
RTN1
reticulon 1
chr6_+_31949801 21.17 ENST00000428956.2
ENST00000498271.1
C4A
complement component 4A (Rodgers blood group)
chr6_+_31982539 20.91 ENST00000435363.2
ENST00000425700.2
C4B
complement component 4B (Chido blood group)
chr6_+_32407619 20.80 ENST00000395388.2
ENST00000374982.5
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr11_-_116968987 20.68 ENST00000434315.2
ENST00000292055.4
ENST00000375288.1
ENST00000542607.1
ENST00000445177.1
ENST00000375300.1
ENST00000446921.2
SIK3
SIK family kinase 3
chr13_+_50070491 20.67 ENST00000496612.1
ENST00000357596.3
ENST00000485919.1
ENST00000442195.1
PHF11
PHD finger protein 11
chr1_+_22964073 20.57 ENST00000402322.1
C1QA
complement component 1, q subcomponent, A chain
chr8_-_102803163 20.45 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD
neurocalcin delta
chr17_-_62009621 20.39 ENST00000349817.2
ENST00000392795.3
CD79B
CD79b molecule, immunoglobulin-associated beta
chr16_-_68033356 20.11 ENST00000393847.1
ENST00000573808.1
ENST00000572624.1
DPEP2
dipeptidase 2
chr13_-_46756351 20.09 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr16_+_31366455 19.95 ENST00000268296.4
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr19_+_1067492 19.92 ENST00000586866.1
HMHA1
histocompatibility (minor) HA-1
chr11_+_62475130 19.85 ENST00000294117.5
GNG3
guanine nucleotide binding protein (G protein), gamma 3
chr12_-_54121212 19.18 ENST00000548263.1
ENST00000430117.2
ENST00000550804.1
ENST00000549173.1
ENST00000551900.1
ENST00000546619.1
ENST00000548177.1
ENST00000549349.1
CALCOCO1
calcium binding and coiled-coil domain 1
chr17_-_34524157 19.04 ENST00000378354.4
ENST00000394484.1
CCL3L3
chemokine (C-C motif) ligand 3-like 3
chr14_-_25103472 18.73 ENST00000216341.4
ENST00000382542.1
ENST00000382540.1
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr11_+_67033881 18.72 ENST00000308595.5
ENST00000526285.1
ADRBK1
adrenergic, beta, receptor kinase 1
chr12_-_54121261 18.65 ENST00000549784.1
ENST00000262059.4
CALCOCO1
calcium binding and coiled-coil domain 1
chr11_+_60739115 18.23 ENST00000344028.5
ENST00000346437.4
CD6
CD6 molecule
chr21_-_46348694 17.89 ENST00000355153.4
ENST00000397850.2
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr12_+_25205446 17.69 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP
lymphoid-restricted membrane protein
chr12_+_25205568 17.46 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr19_-_15087839 17.39 ENST00000600144.1
SLC1A6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr5_-_108745689 17.37 ENST00000361189.2
PJA2
praja ring finger 2, E3 ubiquitin protein ligase
chr17_-_62009702 17.17 ENST00000006750.3
CD79B
CD79b molecule, immunoglobulin-associated beta
chrX_+_48542168 17.09 ENST00000376701.4
WAS
Wiskott-Aldrich syndrome
chr6_+_32709119 17.04 ENST00000374940.3
HLA-DQA2
major histocompatibility complex, class II, DQ alpha 2
chr1_+_161185032 16.94 ENST00000367992.3
ENST00000289902.1
FCER1G
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
chr19_-_51875894 16.83 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
NKG7
natural killer cell group 7 sequence
chr2_+_68592305 16.79 ENST00000234313.7
PLEK
pleckstrin
chr14_-_25103388 16.70 ENST00000526004.1
ENST00000415355.3
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr17_-_10017864 16.68 ENST00000323816.4
GAS7
growth arrest-specific 7
chr2_-_90538397 16.66 ENST00000443397.3
RP11-685N3.1
Uncharacterized protein
chr11_+_108093559 16.65 ENST00000278616.4
ATM
ataxia telangiectasia mutated
chr18_-_74701962 16.64 ENST00000585201.1
MBP
myelin basic protein
chr11_+_60739140 16.62 ENST00000313421.7
CD6
CD6 molecule
chr1_-_168513229 16.59 ENST00000367819.2
XCL2
chemokine (C motif) ligand 2
chr6_-_32920794 16.54 ENST00000395305.3
ENST00000395303.3
ENST00000374843.4
ENST00000429234.1
HLA-DMA
XXbac-BPG181M17.5
major histocompatibility complex, class II, DM alpha
Uncharacterized protein
chr2_+_87565634 16.46 ENST00000421835.2
IGKV3OR2-268
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr5_-_138725560 16.04 ENST00000412103.2
ENST00000457570.2
MZB1
marginal zone B and B1 cell-specific protein
chr16_+_2802623 16.02 ENST00000576924.1
ENST00000575009.1
ENST00000576415.1
ENST00000571378.1
SRRM2
serine/arginine repetitive matrix 2
chr5_-_138725594 15.87 ENST00000302125.8
MZB1
marginal zone B and B1 cell-specific protein
chr14_-_21493884 15.86 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
NDRG2
NDRG family member 2
chr22_+_22707260 15.45 ENST00000390293.1
IGLV5-48
immunoglobulin lambda variable 5-48 (non-functional)
chr9_+_115913222 15.44 ENST00000259392.3
SLC31A2
solute carrier family 31 (copper transporter), member 2
chr11_-_64885111 15.35 ENST00000528598.1
ENST00000310597.4
ZNHIT2
zinc finger, HIT-type containing 2
chr12_+_7055631 15.11 ENST00000543115.1
ENST00000399448.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr19_-_36233332 14.86 ENST00000592537.1
ENST00000246532.1
ENST00000344990.3
ENST00000588992.1
IGFLR1
IGF-like family receptor 1
chr1_+_111415757 14.75 ENST00000429072.2
ENST00000271324.5
CD53
CD53 molecule
chr9_-_34710066 14.64 ENST00000378792.1
ENST00000259607.2
CCL21
chemokine (C-C motif) ligand 21
chr3_+_45067659 14.34 ENST00000296130.4
CLEC3B
C-type lectin domain family 3, member B
chr10_+_70847852 14.19 ENST00000242465.3
SRGN
serglycin
chr5_-_149492904 14.14 ENST00000286301.3
ENST00000511344.1
CSF1R
colony stimulating factor 1 receptor
chr2_+_103035102 14.08 ENST00000264260.2
IL18RAP
interleukin 18 receptor accessory protein
chr11_+_121322832 13.93 ENST00000260197.7
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr17_-_62084241 13.85 ENST00000449662.2
ICAM2
intercellular adhesion molecule 2
chr11_+_1889880 13.79 ENST00000405957.2
LSP1
lymphocyte-specific protein 1
chrX_-_70331298 13.72 ENST00000456850.2
ENST00000473378.1
ENST00000487883.1
ENST00000374202.2
IL2RG
interleukin 2 receptor, gamma
chrY_+_2709906 13.71 ENST00000430575.1
RPS4Y1
ribosomal protein S4, Y-linked 1
chr6_+_42847649 13.69 ENST00000424341.2
ENST00000602561.1
RPL7L1
ribosomal protein L7-like 1
chr6_+_31582961 13.67 ENST00000376059.3
ENST00000337917.7
AIF1
allograft inflammatory factor 1
chr3_+_50284321 13.65 ENST00000451956.1
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr14_-_21493649 13.63 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG2
NDRG family member 2
chr12_-_8218997 13.61 ENST00000307637.4
C3AR1
complement component 3a receptor 1
chr6_-_31514516 13.60 ENST00000303892.5
ENST00000483251.1
ATP6V1G2
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr3_-_18466026 13.58 ENST00000417717.2
SATB1
SATB homeobox 1
chr17_+_25958174 13.56 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
LGALS9
lectin, galactoside-binding, soluble, 9
chr22_+_23264766 13.39 ENST00000390331.2
IGLC7
immunoglobulin lambda constant 7
chr2_+_68961934 13.28 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr6_+_292051 13.21 ENST00000344450.5
DUSP22
dual specificity phosphatase 22
chr2_-_89278535 13.18 ENST00000390247.2
IGKV3-7
immunoglobulin kappa variable 3-7 (non-functional)
chr1_-_184006829 13.15 ENST00000361927.4
COLGALT2
collagen beta(1-O)galactosyltransferase 2
chr17_+_7239821 13.10 ENST00000158762.3
ENST00000570457.2
ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr5_+_156696362 13.09 ENST00000377576.3
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr8_-_19540086 12.90 ENST00000332246.6
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr2_-_89327228 12.82 ENST00000483158.1
IGKV3-11
immunoglobulin kappa variable 3-11
chr2_+_68961905 12.81 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr5_+_35856951 12.67 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R
interleukin 7 receptor
chrX_+_37639264 12.64 ENST00000378588.4
CYBB
cytochrome b-245, beta polypeptide
chr1_+_158801095 12.59 ENST00000368141.4
MNDA
myeloid cell nuclear differentiation antigen
chr7_-_37024665 12.58 ENST00000396040.2
ELMO1
engulfment and cell motility 1
chr18_+_32558208 12.53 ENST00000436190.2
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr6_+_31553978 12.51 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
LST1
leukocyte specific transcript 1
chr6_+_31553901 12.49 ENST00000418507.2
ENST00000438075.2
ENST00000376100.3
ENST00000376111.4
LST1
leukocyte specific transcript 1
chr5_-_42811986 12.38 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr22_-_50524298 12.30 ENST00000311597.5
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr3_+_40518599 12.22 ENST00000314686.5
ENST00000447116.2
ENST00000429348.2
ENST00000456778.1
ZNF619
zinc finger protein 619
chr1_-_150980828 12.21 ENST00000361936.5
ENST00000361738.6
FAM63A
family with sequence similarity 63, member A
chr4_-_71532339 12.17 ENST00000254801.4
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr17_-_1532106 12.09 ENST00000301335.5
ENST00000382147.4
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr6_-_137540477 12.06 ENST00000367735.2
ENST00000367739.4
ENST00000458076.1
ENST00000414770.1
IFNGR1
interferon gamma receptor 1
chr2_+_90211643 11.92 ENST00000390277.2
IGKV3D-11
immunoglobulin kappa variable 3D-11
chr19_+_1067144 11.87 ENST00000313093.2
HMHA1
histocompatibility (minor) HA-1
chr22_-_19512893 11.78 ENST00000403084.1
ENST00000413119.2
CLDN5
claudin 5
chr14_-_94854926 11.76 ENST00000402629.1
ENST00000556091.1
ENST00000554720.1
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr16_+_1578674 11.55 ENST00000253934.5
TMEM204
transmembrane protein 204
chr19_-_6720686 11.51 ENST00000245907.6
C3
complement component 3
chr8_-_21771214 11.48 ENST00000276420.4
DOK2
docking protein 2, 56kDa
chr5_-_42812143 11.39 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr19_-_52255107 11.33 ENST00000595042.1
ENST00000304748.4
FPR1
formyl peptide receptor 1
chr12_-_109025849 11.22 ENST00000228463.6
SELPLG
selectin P ligand
chr19_+_47813110 11.13 ENST00000355085.3
C5AR1
complement component 5a receptor 1
chr12_-_10542617 11.02 ENST00000240618.6
KLRK1
killer cell lectin-like receptor subfamily K, member 1
chr1_+_192544857 11.00 ENST00000367459.3
ENST00000469578.2
RGS1
regulator of G-protein signaling 1
chr22_-_50523760 10.99 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr14_-_25078864 10.98 ENST00000216338.4
ENST00000557220.2
ENST00000382548.4
GZMH
granzyme H (cathepsin G-like 2, protein h-CCPX)
chr1_-_153517473 10.95 ENST00000368715.1
S100A4
S100 calcium binding protein A4
chr19_+_41882598 10.88 ENST00000447302.2
ENST00000544232.1
ENST00000542945.1
ENST00000540732.1
TMEM91
CTC-435M10.3
transmembrane protein 91
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; Uncharacterized protein
chr3_-_39322728 10.84 ENST00000541347.1
ENST00000412814.1
CX3CR1
chemokine (C-X3-C motif) receptor 1
chr1_-_153348067 10.83 ENST00000368737.3
S100A12
S100 calcium binding protein A12
chr5_+_75699149 10.75 ENST00000379730.3
IQGAP2
IQ motif containing GTPase activating protein 2
chr17_+_19281034 10.73 ENST00000308406.5
ENST00000299612.7
MAPK7
mitogen-activated protein kinase 7
chr6_+_28109703 10.55 ENST00000457389.2
ENST00000330236.6
ZKSCAN8
zinc finger with KRAB and SCAN domains 8
chr5_-_137071756 10.54 ENST00000394937.3
ENST00000309755.4
KLHL3
kelch-like family member 3
chr7_-_100844193 10.52 ENST00000440203.2
ENST00000379423.3
ENST00000223114.4
MOGAT3
monoacylglycerol O-acyltransferase 3
chr15_+_84116106 10.49 ENST00000535412.1
ENST00000324537.5
SH3GL3
SH3-domain GRB2-like 3
chr2_+_90153696 10.40 ENST00000417279.2
IGKV3D-15
immunoglobulin kappa variable 3D-15 (gene/pseudogene)
chr12_-_9760482 10.40 ENST00000229402.3
KLRB1
killer cell lectin-like receptor subfamily B, member 1
chr17_-_37308824 10.40 ENST00000415163.1
ENST00000441877.1
ENST00000444911.2
PLXDC1
plexin domain containing 1
chr6_+_142468361 10.35 ENST00000367630.4
VTA1
vesicle (multivesicular body) trafficking 1
chr11_+_65647280 10.32 ENST00000307886.3
ENST00000528419.1
ENST00000526034.1
CTSW
cathepsin W
chr2_+_143886877 10.31 ENST00000295095.6
ARHGAP15
Rho GTPase activating protein 15
chr5_+_67588391 10.27 ENST00000523872.1
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr1_-_92951607 10.27 ENST00000427103.1
GFI1
growth factor independent 1 transcription repressor
chr7_+_99971129 10.20 ENST00000394000.2
ENST00000350573.2
PILRA
paired immunoglobin-like type 2 receptor alpha
chr3_+_113251143 10.19 ENST00000264852.4
ENST00000393830.3
SIDT1
SID1 transmembrane family, member 1
chr11_+_2323349 10.17 ENST00000381121.3
TSPAN32
tetraspanin 32
chr6_-_41168920 10.14 ENST00000483722.1
TREML2
triggering receptor expressed on myeloid cells-like 2
chr3_-_187454281 10.14 ENST00000232014.4
BCL6
B-cell CLL/lymphoma 6
chr3_+_122044084 10.13 ENST00000264474.3
ENST00000479204.1
CSTA
cystatin A (stefin A)
chr2_+_90273679 10.10 ENST00000423080.2
IGKV3D-7
immunoglobulin kappa variable 3D-7
chr6_+_31554456 10.07 ENST00000339530.4
LST1
leukocyte specific transcript 1
chr19_-_15529790 10.02 ENST00000596195.1
ENST00000595067.1
ENST00000595465.2
ENST00000397410.5
ENST00000600247.1
AKAP8L
A kinase (PRKA) anchor protein 8-like
chr3_+_57541975 10.01 ENST00000487257.1
ENST00000311180.8
PDE12
phosphodiesterase 12
chr1_+_17634689 9.98 ENST00000375453.1
ENST00000375448.4
PADI4
peptidyl arginine deiminase, type IV
chr1_+_174843548 9.97 ENST00000478442.1
ENST00000465412.1
RABGAP1L
RAB GTPase activating protein 1-like
chr14_-_23285069 9.87 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr2_+_89890533 9.81 ENST00000429992.2
IGKV2D-40
immunoglobulin kappa variable 2D-40
chr8_-_19540266 9.73 ENST00000311540.4
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr19_-_2151523 9.71 ENST00000350812.6
ENST00000355272.6
ENST00000356926.4
ENST00000345016.5
AP3D1
adaptor-related protein complex 3, delta 1 subunit
chr6_-_152958521 9.70 ENST00000367255.5
ENST00000265368.4
ENST00000448038.1
ENST00000341594.5
SYNE1
spectrin repeat containing, nuclear envelope 1
chr9_-_98079965 9.69 ENST00000289081.3
FANCC
Fanconi anemia, complementation group C
chr3_-_138763734 9.65 ENST00000413199.1
ENST00000502927.2
PRR23C
proline rich 23C
chr19_-_10445399 9.65 ENST00000592945.1
ICAM3
intercellular adhesion molecule 3
chr19_-_42498369 9.63 ENST00000302102.5
ENST00000545399.1
ATP1A3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chrX_-_70838306 9.54 ENST00000373691.4
ENST00000373693.3
CXCR3
chemokine (C-X-C motif) receptor 3
chr19_-_18391708 9.54 ENST00000600972.1
JUND
jun D proto-oncogene
chr3_-_13009168 9.49 ENST00000273221.4
IQSEC1
IQ motif and Sec7 domain 1
chr16_+_72088376 9.48 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP
HPR
haptoglobin
haptoglobin-related protein
chrX_+_37639302 9.47 ENST00000545017.1
ENST00000536160.1
CYBB
cytochrome b-245, beta polypeptide
chr18_+_13612613 9.46 ENST00000586765.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr22_+_22786288 9.43 ENST00000390301.2
IGLV1-36
immunoglobulin lambda variable 1-36
chr1_-_207095324 9.40 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr2_-_175462934 9.36 ENST00000392546.2
ENST00000436221.1
WIPF1
WAS/WASL interacting protein family, member 1
chrX_-_78622805 9.34 ENST00000373298.2
ITM2A
integral membrane protein 2A
chr5_+_75699040 9.29 ENST00000274364.6
IQGAP2
IQ motif containing GTPase activating protein 2
chr12_+_7055767 9.25 ENST00000447931.2
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr11_-_58343319 9.22 ENST00000395074.2
LPXN
leupaxin
chr7_-_36634181 9.17 ENST00000538464.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr2_+_201980827 9.16 ENST00000309955.3
ENST00000443227.1
ENST00000341222.6
ENST00000355558.4
ENST00000340870.5
ENST00000341582.6
CFLAR
CASP8 and FADD-like apoptosis regulator
chr1_+_155829286 9.16 ENST00000368324.4
SYT11
synaptotagmin XI
chr15_+_25200074 9.12 ENST00000390687.4
ENST00000584968.1
ENST00000346403.6
ENST00000554227.2
SNRPN
small nuclear ribonucleoprotein polypeptide N

Network of associatons between targets according to the STRING database.

First level regulatory network of RUNX1_RUNX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
20.9 62.6 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
14.5 43.6 GO:1902997 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
13.6 13.6 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
12.8 63.8 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
9.7 77.2 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
9.5 28.5 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
9.3 37.3 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
9.2 9.2 GO:1905154 negative regulation of membrane invagination(GO:1905154)
8.9 26.7 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
8.5 34.1 GO:2000537 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
8.2 32.7 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
7.1 49.6 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
5.7 17.1 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
5.7 45.3 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
5.7 22.6 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276) chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
5.6 16.7 GO:1904884 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
5.5 11.0 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
5.5 21.9 GO:0042412 taurine biosynthetic process(GO:0042412)
5.4 16.1 GO:0002818 intracellular defense response(GO:0002818)
4.9 14.6 GO:0097026 dendritic cell dendrite assembly(GO:0097026) regulation of dendritic cell dendrite assembly(GO:2000547)
4.4 22.1 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
4.2 12.5 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
3.9 70.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
3.8 11.3 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
3.7 11.2 GO:0050902 leukocyte adhesive activation(GO:0050902)
3.7 11.1 GO:0038178 complement component C5a signaling pathway(GO:0038178)
3.6 10.8 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
3.5 17.6 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
3.5 17.4 GO:0070778 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
3.4 17.1 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
3.4 10.3 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
3.3 19.6 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
3.2 9.7 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
3.2 9.7 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
3.2 12.8 GO:0002884 negative regulation of hypersensitivity(GO:0002884)
3.2 9.5 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
3.2 18.9 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
3.0 3.0 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
3.0 11.9 GO:2001193 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
3.0 17.9 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
2.9 61.8 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
2.9 8.7 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
2.8 16.8 GO:0070560 protein secretion by platelet(GO:0070560)
2.8 27.6 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
2.7 8.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
2.6 18.5 GO:0043654 recognition of apoptotic cell(GO:0043654)
2.6 39.0 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
2.6 10.3 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
2.6 7.7 GO:0051595 response to methylglyoxal(GO:0051595)
2.6 28.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
2.5 7.5 GO:1901731 positive regulation of platelet aggregation(GO:1901731) regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
2.5 7.4 GO:0090035 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
2.5 7.4 GO:0045925 positive regulation of female receptivity(GO:0045925)
2.5 22.1 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308)
2.4 7.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
2.3 7.0 GO:0039506 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
2.3 32.2 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
2.2 8.9 GO:0019046 release from viral latency(GO:0019046)
2.2 19.9 GO:1903416 response to glycoside(GO:1903416)
2.2 8.8 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
2.2 10.8 GO:0071895 odontoblast differentiation(GO:0071895)
2.1 10.7 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
2.1 23.6 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
2.1 25.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
2.1 6.3 GO:1905224 clathrin-coated pit assembly(GO:1905224)
2.1 6.3 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
2.1 8.3 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
2.1 24.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
2.0 14.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
2.0 10.0 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
2.0 8.0 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
2.0 13.7 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
2.0 23.4 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
1.9 17.5 GO:0045217 cell-cell junction maintenance(GO:0045217)
1.9 27.1 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
1.9 3.9 GO:0090306 oocyte maturation(GO:0001556) spindle assembly involved in female meiosis(GO:0007056) spindle assembly involved in meiosis(GO:0090306)
1.9 13.5 GO:0045007 depurination(GO:0045007)
1.9 264.1 GO:0006958 complement activation, classical pathway(GO:0006958)
1.8 5.5 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
1.8 7.4 GO:0060313 negative regulation of blood vessel remodeling(GO:0060313)
1.8 11.0 GO:0061737 leukotriene signaling pathway(GO:0061737)
1.8 7.3 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
1.8 25.4 GO:0047484 regulation of response to osmotic stress(GO:0047484)
1.8 3.6 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
1.8 14.5 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
1.8 7.2 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
1.8 26.6 GO:0015671 oxygen transport(GO:0015671)
1.7 5.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
1.7 5.2 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
1.7 5.1 GO:1904597 regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204)
1.7 5.1 GO:0033212 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
1.7 10.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
1.7 6.7 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
1.7 19.8 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
1.6 13.1 GO:0015705 iodide transport(GO:0015705)
1.6 21.3 GO:0030321 transepithelial chloride transport(GO:0030321)
1.6 11.4 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
1.6 4.9 GO:1903027 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
1.6 3.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
1.6 4.8 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
1.6 56.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
1.6 4.7 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
1.6 9.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
1.5 4.6 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
1.5 4.6 GO:0072218 ascending thin limb development(GO:0072021) metanephric ascending thin limb development(GO:0072218)
1.5 15.2 GO:0035434 copper ion transmembrane transport(GO:0035434)
1.5 4.5 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
1.5 16.4 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
1.5 4.4 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
1.5 4.4 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
1.5 4.4 GO:0007538 primary sex determination(GO:0007538)
1.5 4.4 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
1.5 10.2 GO:0033227 dsRNA transport(GO:0033227)
1.4 2.9 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
1.4 12.9 GO:0072017 distal tubule development(GO:0072017)
1.4 1.4 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
1.4 2.9 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
1.4 99.8 GO:0006968 cellular defense response(GO:0006968)
1.4 11.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
1.4 4.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
1.4 2.8 GO:1901072 glucosamine-containing compound catabolic process(GO:1901072)
1.4 4.1 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
1.3 5.3 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
1.3 5.2 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
1.3 3.9 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
1.3 5.1 GO:0032053 ciliary basal body organization(GO:0032053)
1.3 7.7 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
1.3 1.3 GO:0001810 regulation of type I hypersensitivity(GO:0001810) positive regulation of type I hypersensitivity(GO:0001812) type I hypersensitivity(GO:0016068)
1.3 3.8 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
1.3 3.8 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
1.3 3.8 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
1.3 3.8 GO:0007518 myoblast fate determination(GO:0007518)
1.2 3.7 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
1.2 6.1 GO:0048388 endosomal lumen acidification(GO:0048388)
1.2 7.3 GO:0006824 cobalt ion transport(GO:0006824)
1.2 7.3 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
1.2 3.6 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
1.2 8.3 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
1.2 3.5 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
1.2 10.4 GO:0050862 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857) positive regulation of T cell receptor signaling pathway(GO:0050862)
1.1 4.6 GO:1905073 proepicardium development(GO:0003342) septum transversum development(GO:0003343) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
1.1 3.4 GO:0060018 astrocyte fate commitment(GO:0060018)
1.1 13.7 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
1.1 13.6 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
1.1 4.5 GO:0002266 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
1.1 9.0 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
1.1 3.4 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
1.1 11.1 GO:0002223 innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223)
1.1 13.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.1 22.0 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
1.1 4.4 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
1.1 15.2 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
1.1 4.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
1.1 8.6 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
1.1 22.4 GO:0001829 trophectodermal cell differentiation(GO:0001829)
1.1 11.7 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
1.1 7.5 GO:0070269 pyroptosis(GO:0070269)
1.0 16.8 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
1.0 3.1 GO:0061760 antifungal innate immune response(GO:0061760)
1.0 2.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
1.0 4.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
1.0 7.2 GO:0016098 monoterpenoid metabolic process(GO:0016098)
1.0 1.0 GO:0048290 isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296)
1.0 5.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
1.0 2.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
1.0 3.0 GO:0016045 detection of bacterium(GO:0016045) cellular response to muramyl dipeptide(GO:0071225)
1.0 3.0 GO:1904640 response to methionine(GO:1904640)
1.0 1.0 GO:0006542 glutamine biosynthetic process(GO:0006542)
1.0 7.7 GO:0009304 tRNA transcription(GO:0009304)
1.0 5.7 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
1.0 12.4 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
1.0 1.0 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
1.0 2.9 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.9 10.3 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.9 3.7 GO:0048749 compound eye development(GO:0048749)
0.9 2.8 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.9 8.4 GO:0005980 glycogen catabolic process(GO:0005980)
0.9 2.8 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.9 13.6 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.9 1.8 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.9 10.8 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.9 4.5 GO:0090649 rRNA transport(GO:0051029) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.9 7.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.9 3.6 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.9 13.3 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.9 8.9 GO:0051597 response to methylmercury(GO:0051597)
0.9 9.7 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.9 2.6 GO:0035696 monocyte extravasation(GO:0035696) activation of meiosis(GO:0090427) regulation of monocyte extravasation(GO:2000437)
0.9 7.9 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.9 7.8 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.9 7.7 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.9 4.3 GO:1904383 response to sodium phosphate(GO:1904383)
0.9 2.6 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.9 8.5 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.8 3.4 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.8 0.8 GO:0060467 negative regulation of fertilization(GO:0060467)
0.8 2.5 GO:0030449 regulation of complement activation(GO:0030449)
0.8 5.0 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.8 4.9 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.8 4.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.8 4.0 GO:0071918 urea transmembrane transport(GO:0071918)
0.8 1.6 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.8 5.6 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.8 7.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.8 1.6 GO:0009957 epidermal cell fate specification(GO:0009957)
0.8 3.9 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.8 3.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.8 7.7 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.8 3.8 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.8 2.3 GO:0001694 histamine biosynthetic process(GO:0001694)
0.8 3.1 GO:0030242 pexophagy(GO:0030242)
0.8 35.0 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.8 3.0 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.8 2.3 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.8 1.5 GO:0050955 thermoception(GO:0050955)
0.8 3.0 GO:0071673 positive regulation of smooth muscle cell chemotaxis(GO:0071673) response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.7 13.5 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.7 6.0 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.7 3.7 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.7 3.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.7 5.9 GO:0048793 pronephros development(GO:0048793)
0.7 2.2 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.7 0.7 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.7 4.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.7 94.3 GO:0002377 immunoglobulin production(GO:0002377)
0.7 2.9 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.7 1.4 GO:0031133 regulation of axon diameter(GO:0031133)
0.7 5.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.7 5.7 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.7 5.0 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.7 1.4 GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
0.7 3.5 GO:0009595 detection of biotic stimulus(GO:0009595)
0.7 1.4 GO:0048484 enteric nervous system development(GO:0048484)
0.7 2.1 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.7 4.8 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.7 11.5 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.7 4.0 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.7 3.3 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.7 3.3 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.7 0.7 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.7 2.0 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.7 14.6 GO:0006068 ethanol catabolic process(GO:0006068)
0.7 2.7 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.7 6.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.7 21.7 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.7 2.6 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.6 6.4 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.6 57.0 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.6 10.8 GO:0050832 defense response to fungus(GO:0050832)
0.6 1.9 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.6 6.3 GO:0090128 regulation of synapse maturation(GO:0090128)
0.6 1.3 GO:0051414 response to cortisol(GO:0051414)
0.6 3.1 GO:2000301 myeloid progenitor cell differentiation(GO:0002318) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.6 14.3 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.6 6.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.6 15.9 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.6 4.9 GO:0035897 proteolysis in other organism(GO:0035897)
0.6 9.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.6 4.9 GO:1905097 protein localization to endoplasmic reticulum exit site(GO:0070973) regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.6 3.0 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.6 3.0 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.6 9.5 GO:0006071 glycerol metabolic process(GO:0006071)
0.6 4.7 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.6 1.8 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.6 24.2 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.6 4.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.6 5.3 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.6 1.2 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.6 2.3 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.6 4.6 GO:0002051 osteoblast fate commitment(GO:0002051)
0.6 5.8 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.6 10.4 GO:0098743 cell aggregation(GO:0098743)
0.6 4.6 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.6 2.3 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.6 0.6 GO:0002326 B cell lineage commitment(GO:0002326)
0.6 1.7 GO:0051697 protein delipidation(GO:0051697)
0.6 7.4 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.6 7.8 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.6 36.9 GO:0031295 T cell costimulation(GO:0031295)
0.5 1.6 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.5 4.9 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.5 3.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.5 4.3 GO:0071569 protein ufmylation(GO:0071569)
0.5 1.6 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.5 10.6 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.5 9.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.5 8.3 GO:0030308 negative regulation of cell growth(GO:0030308)
0.5 19.2 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.5 2.1 GO:0019086 late viral transcription(GO:0019086)
0.5 8.7 GO:0019374 galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374)
0.5 1.5 GO:0016999 antibiotic metabolic process(GO:0016999) cellular amide catabolic process(GO:0043605)
0.5 14.3 GO:0007616 long-term memory(GO:0007616)
0.5 3.0 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.5 1.0 GO:1901911 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.5 5.0 GO:0032264 IMP salvage(GO:0032264)
0.5 1.5 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.5 5.5 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.5 36.1 GO:0030183 B cell differentiation(GO:0030183)
0.5 2.5 GO:0000920 cell separation after cytokinesis(GO:0000920) negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.5 10.1 GO:0071593 lymphocyte aggregation(GO:0071593)
0.5 4.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.5 2.9 GO:0001661 conditioned taste aversion(GO:0001661) amygdala development(GO:0021764)
0.5 3.3 GO:0023014 signal transduction by protein phosphorylation(GO:0023014)
0.5 6.1 GO:0045730 respiratory burst(GO:0045730)
0.5 3.7 GO:0032306 regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308)
0.5 6.0 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248) sodium ion export from cell(GO:0036376) potassium ion import across plasma membrane(GO:1990573)
0.4 5.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.4 1.8 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.4 8.8 GO:0016180 snRNA processing(GO:0016180)
0.4 1.3 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.4 0.9 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.4 5.7 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.4 3.0 GO:0098712 L-glutamate import across plasma membrane(GO:0098712)
0.4 3.0 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.4 6.8 GO:0042574 retinal metabolic process(GO:0042574)
0.4 24.7 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672) negative regulation of leukocyte proliferation(GO:0070664)
0.4 1.7 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.4 2.5 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.4 1.6 GO:0009386 translational attenuation(GO:0009386)
0.4 1.2 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.4 2.4 GO:0071104 response to interleukin-9(GO:0071104)
0.4 2.4 GO:0045072 regulation of interferon-gamma biosynthetic process(GO:0045072)
0.4 5.6 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.4 6.4 GO:0007635 chemosensory behavior(GO:0007635)
0.4 1.6 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.4 11.5 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.4 16.7 GO:0006536 glutamate metabolic process(GO:0006536)
0.4 3.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.4 1.5 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.4 6.9 GO:0019430 removal of superoxide radicals(GO:0019430)
0.4 3.1 GO:0045023 G0 to G1 transition(GO:0045023)
0.4 0.4 GO:0032714 negative regulation of interleukin-5 production(GO:0032714)
0.4 6.4 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.4 1.5 GO:0050705 negative regulation of interleukin-1 alpha production(GO:0032690) regulation of interleukin-1 alpha secretion(GO:0050705) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.4 11.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.4 3.0 GO:0021546 rhombomere development(GO:0021546)
0.4 2.6 GO:0045471 response to ethanol(GO:0045471)
0.4 7.0 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.4 1.5 GO:0060322 head development(GO:0060322)
0.4 10.7 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.4 1.5 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.4 2.2 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.4 4.3 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.4 3.9 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.3 5.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.3 1.4 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.3 13.3 GO:0033572 transferrin transport(GO:0033572)
0.3 2.0 GO:0006776 vitamin A metabolic process(GO:0006776)
0.3 3.0 GO:0006379 mRNA cleavage(GO:0006379)
0.3 1.7 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.3 3.7 GO:0032364 oxygen homeostasis(GO:0032364)
0.3 3.6 GO:0015884 folic acid transport(GO:0015884)
0.3 5.9 GO:0007021 tubulin complex assembly(GO:0007021)
0.3 1.3 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.3 6.2 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.3 5.2 GO:0051639 actin filament network formation(GO:0051639)
0.3 2.3 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.3 3.5 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.3 1.6 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.3 2.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.3 2.5 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.3 5.7 GO:0044804 nucleophagy(GO:0044804)
0.3 1.6 GO:0031642 negative regulation of myelination(GO:0031642)
0.3 1.9 GO:0097178 ruffle assembly(GO:0097178)
0.3 0.6 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.3 2.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.3 4.6 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.3 1.5 GO:0032418 lysosome localization(GO:0032418)
0.3 4.0 GO:0007567 parturition(GO:0007567)
0.3 10.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.3 19.6 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.3 3.6 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.3 12.8 GO:0030101 natural killer cell activation(GO:0030101)
0.3 4.4 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.3 3.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.3 1.2 GO:0010761 fibroblast migration(GO:0010761)
0.3 6.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.3 0.6 GO:0006522 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080)
0.3 0.6 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.3 12.1 GO:0016079 synaptic vesicle exocytosis(GO:0016079)
0.3 7.6 GO:0009967 positive regulation of signal transduction(GO:0009967)
0.3 10.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.3 4.2 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.3 2.7 GO:1901739 regulation of myoblast fusion(GO:1901739)
0.3 0.5 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.3 1.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.3 0.8 GO:0050757 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.3 3.5 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.3 2.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.3 3.7 GO:1903817 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.3 3.3 GO:0061436 establishment of skin barrier(GO:0061436)
0.3 2.8 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.3 20.4 GO:0021510 spinal cord development(GO:0021510)
0.2 3.7 GO:0090314 positive regulation of protein targeting to membrane(GO:0090314)
0.2 21.7 GO:0006903 vesicle targeting(GO:0006903)
0.2 2.7 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.2 4.3 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.2 2.6 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.2 9.0 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.2 0.9 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.2 2.6 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.2 8.4 GO:0042417 dopamine metabolic process(GO:0042417)
0.2 8.2 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.2 4.4 GO:0034389 lipid particle organization(GO:0034389)
0.2 7.6 GO:0018149 peptide cross-linking(GO:0018149)
0.2 1.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.2 5.5 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.2 5.5 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.2 4.2 GO:0006768 biotin metabolic process(GO:0006768)
0.2 1.1 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.2 2.6 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.2 0.4 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.2 1.3 GO:0072643 interferon-gamma secretion(GO:0072643)
0.2 1.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.2 2.8 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.2 0.8 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.2 2.3 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.2 1.0 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.2 7.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.2 1.0 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.2 6.0 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.2 6.6 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.2 2.7 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.2 2.6 GO:1903844 regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.2 9.3 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.2 4.3 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.2 2.0 GO:0070977 bone maturation(GO:0070977)
0.2 1.6 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.2 1.6 GO:0051775 response to redox state(GO:0051775)
0.2 1.2 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.2 1.7 GO:0030324 lung development(GO:0030324)
0.2 0.6 GO:0030199 collagen fibril organization(GO:0030199)
0.2 0.8 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.2 3.1 GO:1901216 positive regulation of neuron death(GO:1901216)
0.2 1.1 GO:0018343 protein farnesylation(GO:0018343)
0.2 7.8 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.2 7.1 GO:0005975 carbohydrate metabolic process(GO:0005975)
0.2 2.7 GO:0032026 response to magnesium ion(GO:0032026)
0.2 3.6 GO:0006590 thyroid hormone generation(GO:0006590)
0.2 0.7 GO:0090527 actin filament reorganization(GO:0090527)
0.2 3.9 GO:0043536 positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.2 4.4 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.2 2.3 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.2 1.0 GO:0007320 insemination(GO:0007320)
0.2 5.7 GO:0050919 negative chemotaxis(GO:0050919)
0.2 10.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 3.0 GO:0033198 response to ATP(GO:0033198)
0.2 2.7 GO:0051028 mRNA transport(GO:0051028)
0.2 6.5 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.2 0.8 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.2 0.3 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.2 1.6 GO:1901889 negative regulation of cell junction assembly(GO:1901889)
0.2 1.5 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.2 2.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 1.6 GO:0015937 coenzyme A metabolic process(GO:0015936) coenzyme A biosynthetic process(GO:0015937)
0.2 2.8 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.2 1.7 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.2 0.5 GO:0015808 L-alanine transport(GO:0015808)
0.2 3.9 GO:0032456 endocytic recycling(GO:0032456)
0.1 15.5 GO:0019722 calcium-mediated signaling(GO:0019722)
0.1 0.9 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 1.7 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 3.2 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.1 36.4 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.1 20.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 2.2 GO:0048665 neuron fate specification(GO:0048665)
0.1 15.4 GO:0007605 sensory perception of sound(GO:0007605)
0.1 3.2 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.9 GO:0006284 base-excision repair(GO:0006284)
0.1 0.5 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 0.4 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) positive regulation of microtubule binding(GO:1904528)
0.1 6.5 GO:0000045 autophagosome assembly(GO:0000045)
0.1 3.7 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 2.1 GO:0003197 endocardial cushion development(GO:0003197)
0.1 3.0 GO:0015695 organic cation transport(GO:0015695)
0.1 1.0 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 1.1 GO:0003228 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.1 0.7 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894) positive regulation of adherens junction organization(GO:1903393)
0.1 0.9 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 0.3 GO:0006014 D-ribose metabolic process(GO:0006014)
0.1 0.2 GO:0010656 negative regulation of muscle cell apoptotic process(GO:0010656)
0.1 3.1 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 2.3 GO:0007032 endosome organization(GO:0007032)
0.1 0.8 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 1.7 GO:0097435 fibril organization(GO:0097435)
0.1 0.9 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.1 9.6 GO:0050680 negative regulation of epithelial cell proliferation(GO:0050680)
0.1 0.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 1.0 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 1.7 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.1 3.9 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 0.7 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155) regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 4.9 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 4.2 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 1.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 1.3 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 3.2 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.1 3.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 0.4 GO:0030432 peristalsis(GO:0030432) somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 1.8 GO:0072384 organelle transport along microtubule(GO:0072384)
0.1 1.0 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 3.8 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 0.2 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 1.1 GO:0031935 regulation of chromatin silencing(GO:0031935)
0.1 0.9 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 0.4 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 1.0 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 2.3 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.3 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.1 0.6 GO:0009410 response to xenobiotic stimulus(GO:0009410)
0.1 1.1 GO:0045026 plasma membrane fusion(GO:0045026)
0.1 2.5 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.1 0.5 GO:0044241 lipid digestion(GO:0044241)
0.1 1.0 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.1 0.2 GO:0001555 oocyte growth(GO:0001555)
0.0 0.0 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.3 GO:1990118 gastric acid secretion(GO:0001696) sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 2.8 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.2 GO:0030208 dermatan sulfate metabolic process(GO:0030205) dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.4 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.7 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.7 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.6 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.0 1.4 GO:0007270 neuron-neuron synaptic transmission(GO:0007270)
0.0 2.9 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 0.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0045779 negative regulation of bone resorption(GO:0045779) negative regulation of bone remodeling(GO:0046851)
0.0 0.5 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.2 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.2 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.3 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.9 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 2.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.6 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.2 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.2 GO:0006833 water transport(GO:0006833)
0.0 0.2 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
14.4 43.3 GO:0071749 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
8.3 33.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
8.2 32.7 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
5.4 37.6 GO:0019815 B cell receptor complex(GO:0019815)
4.5 27.1 GO:1990037 Lewy body core(GO:1990037)
4.4 13.3 GO:0097453 mesaxon(GO:0097453) ensheathing process(GO:1990015)
4.1 20.6 GO:0005602 complement component C1 complex(GO:0005602)
3.9 81.4 GO:0042613 MHC class II protein complex(GO:0042613)
3.7 74.1 GO:0001891 phagocytic cup(GO:0001891)
3.6 17.9 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
3.2 9.7 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
3.0 21.1 GO:0097013 phagocytic vesicle lumen(GO:0097013)
2.9 8.8 GO:0071020 post-spliceosomal complex(GO:0071020)
2.9 14.3 GO:0001652 granular component(GO:0001652)
2.6 2.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
2.6 10.3 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
2.5 10.1 GO:1990246 uniplex complex(GO:1990246)
2.4 7.3 GO:0036398 TCR signalosome(GO:0036398)
2.4 16.6 GO:0033269 internode region of axon(GO:0033269)
2.4 14.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
2.2 24.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
2.1 37.7 GO:0042101 T cell receptor complex(GO:0042101)
2.0 14.1 GO:0044326 dendritic spine neck(GO:0044326)
2.0 10.0 GO:0005899 insulin receptor complex(GO:0005899)
1.8 7.1 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
1.7 8.7 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
1.7 25.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
1.7 28.3 GO:0043020 NADPH oxidase complex(GO:0043020)
1.5 22.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
1.5 32.0 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
1.4 65.8 GO:0019814 immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571)
1.4 5.5 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
1.3 1.3 GO:0071439 clathrin complex(GO:0071439)
1.3 20.1 GO:0005641 nuclear envelope lumen(GO:0005641)
1.3 22.1 GO:0005687 U4 snRNP(GO:0005687)
1.3 7.6 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
1.3 6.3 GO:0089701 U2AF(GO:0089701)
1.3 5.1 GO:0016514 SWI/SNF complex(GO:0016514)
1.2 9.5 GO:0035976 AP1 complex(GO:0035976)
1.1 10.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
1.1 4.5 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
1.1 13.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
1.1 4.5 GO:0033596 TSC1-TSC2 complex(GO:0033596)
1.0 3.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
1.0 43.9 GO:0001772 immunological synapse(GO:0001772)
1.0 7.7 GO:0097504 Gemini of coiled bodies(GO:0097504)
1.0 7.7 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.9 8.3 GO:0005955 calcineurin complex(GO:0005955)
0.9 31.5 GO:0008305 integrin complex(GO:0008305)
0.9 8.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.9 7.9 GO:0097433 dense body(GO:0097433)
0.9 9.5 GO:0042583 chromaffin granule(GO:0042583)
0.9 9.4 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.9 91.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.8 7.8 GO:0044754 autolysosome(GO:0044754)
0.8 68.5 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.8 3.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.7 6.7 GO:0030897 HOPS complex(GO:0030897)
0.7 12.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.7 33.5 GO:0002102 podosome(GO:0002102)
0.7 8.9 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.7 10.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.7 2.6 GO:0016939 kinesin II complex(GO:0016939)
0.6 4.5 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.6 3.7 GO:1990130 Iml1 complex(GO:1990130)
0.6 4.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.6 3.7 GO:0035579 specific granule membrane(GO:0035579)
0.6 4.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.6 10.8 GO:0097342 ripoptosome(GO:0097342)
0.6 5.3 GO:0032039 integrator complex(GO:0032039)
0.6 1.2 GO:0045178 basal part of cell(GO:0045178)
0.6 2.9 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.6 85.1 GO:0031901 early endosome membrane(GO:0031901)
0.6 2.9 GO:0044308 axonal spine(GO:0044308)
0.6 12.8 GO:0034451 centriolar satellite(GO:0034451)
0.6 12.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.6 3.9 GO:0072487 MSL complex(GO:0072487)
0.6 10.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.6 8.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.5 4.9 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.5 2.7 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.5 28.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.5 3.7 GO:1990635 proximal dendrite(GO:1990635)
0.5 2.7 GO:0005594 collagen type IX trimer(GO:0005594)
0.5 6.3 GO:0032585 multivesicular body membrane(GO:0032585)
0.5 3.7 GO:0097361 CIA complex(GO:0097361)
0.5 123.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.5 2.5 GO:0031264 death-inducing signaling complex(GO:0031264)
0.5 5.4 GO:0042588 zymogen granule(GO:0042588)
0.5 54.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.5 6.1 GO:0000815 ESCRT III complex(GO:0000815)
0.5 3.3 GO:0035253 ciliary rootlet(GO:0035253)
0.5 20.8 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.5 5.5 GO:0000242 pericentriolar material(GO:0000242)
0.4 1.8 GO:0005797 Golgi trans cisterna(GO:0000138) Golgi medial cisterna(GO:0005797)
0.4 11.1 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.4 5.3 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.4 1.3 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.4 3.9 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.4 15.4 GO:0000791 euchromatin(GO:0000791)
0.4 2.9 GO:0046581 intercellular canaliculus(GO:0046581)
0.4 29.7 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.4 3.7 GO:0005579 membrane attack complex(GO:0005579)
0.4 17.3 GO:0005720 nuclear heterochromatin(GO:0005720)
0.4 2.3 GO:0034464 BBSome(GO:0034464)
0.4 3.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.4 6.1 GO:0031083 BLOC-1 complex(GO:0031083)
0.4 3.0 GO:0000243 commitment complex(GO:0000243)
0.4 7.4 GO:0005903 brush border(GO:0005903)
0.4 3.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.4 1.8 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.4 2.9 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.4 26.6 GO:0005901 caveola(GO:0005901)
0.3 21.6 GO:0005902 microvillus(GO:0005902)
0.3 4.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.3 7.7 GO:0016580 Sin3 complex(GO:0016580)
0.3 5.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.3 4.2 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.3 5.1 GO:0097512 cardiac myofibril(GO:0097512)
0.3 2.9 GO:0005833 hemoglobin complex(GO:0005833)
0.3 1.6 GO:0070847 core mediator complex(GO:0070847)
0.3 1.9 GO:0036157 outer dynein arm(GO:0036157)
0.3 3.3 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.3 6.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.3 36.7 GO:0072562 blood microparticle(GO:0072562)
0.3 0.9 GO:0043291 RAVE complex(GO:0043291)
0.3 15.4 GO:0005938 cell cortex(GO:0005938)
0.3 16.9 GO:0034707 chloride channel complex(GO:0034707)
0.3 26.7 GO:0043202 lysosomal lumen(GO:0043202)
0.3 0.8 GO:1990761 growth cone lamellipodium(GO:1990761)
0.3 7.8 GO:0016235 aggresome(GO:0016235)
0.3 6.2 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.3 0.8 GO:0071437 invadopodium(GO:0071437)
0.2 2.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 15.0 GO:0015030 Cajal body(GO:0015030)
0.2 6.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.2 19.5 GO:0042734 presynaptic membrane(GO:0042734)
0.2 0.7 GO:0005593 FACIT collagen trimer(GO:0005593)
0.2 12.7 GO:0031902 late endosome membrane(GO:0031902)
0.2 1.5 GO:0002080 acrosomal membrane(GO:0002080)
0.2 2.8 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.2 11.6 GO:0043235 receptor complex(GO:0043235)
0.2 4.2 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.2 1.0 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.2 2.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.2 63.5 GO:0000790 nuclear chromatin(GO:0000790)
0.2 0.6 GO:0032279 asymmetric synapse(GO:0032279)
0.2 9.1 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.2 12.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 2.4 GO:0031430 M band(GO:0031430)
0.2 1.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.2 2.3 GO:0042555 MCM complex(GO:0042555)
0.2 1.9 GO:0097486 multivesicular body lumen(GO:0097486)
0.2 2.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.2 26.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.2 3.7 GO:0031201 SNARE complex(GO:0031201)
0.2 4.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 6.8 GO:0005776 autophagosome(GO:0005776)
0.2 9.7 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.2 8.6 GO:0043195 terminal bouton(GO:0043195)
0.2 20.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.2 1.3 GO:0045180 basal cortex(GO:0045180)
0.2 0.6 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 11.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 230.0 GO:0005887 integral component of plasma membrane(GO:0005887)
0.2 6.8 GO:0001533 cornified envelope(GO:0001533)
0.2 1.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 19.2 GO:0030427 site of polarized growth(GO:0030427)
0.1 1.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 1.0 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 1.3 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 3.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 6.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 3.3 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 11.5 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.1 14.3 GO:0016605 PML body(GO:0016605)
0.1 2.9 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.2 GO:0097060 synaptic membrane(GO:0097060)
0.1 5.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 4.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 2.5 GO:1904115 axon cytoplasm(GO:1904115)
0.1 0.5 GO:0030663 COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663)
0.1 1.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 2.6 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 3.8 GO:0005811 lipid particle(GO:0005811)
0.1 6.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 2.0 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 3.0 GO:0005859 muscle myosin complex(GO:0005859)
0.1 177.4 GO:0016021 integral component of membrane(GO:0016021)
0.1 4.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 0.6 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.2 GO:0097447 dendritic tree(GO:0097447)
0.1 4.4 GO:0031970 organelle envelope lumen(GO:0031970)
0.1 2.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 1.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 67.6 GO:0005615 extracellular space(GO:0005615)
0.1 1.1 GO:0005861 troponin complex(GO:0005861)
0.0 1.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.4 GO:0030175 filopodium(GO:0030175)
0.0 0.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0030315 T-tubule(GO:0030315)
0.0 0.5 GO:0043679 axon terminus(GO:0043679)
0.0 3.8 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.9 GO:0030027 lamellipodium(GO:0030027)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.6 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
20.9 62.6 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
11.0 22.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
8.8 26.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
8.8 26.4 GO:0004917 interleukin-7 receptor activity(GO:0004917)
7.5 22.6 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
5.8 40.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
5.2 15.5 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
5.0 45.3 GO:0043426 MRF binding(GO:0043426)
4.6 64.8 GO:0032395 MHC class II receptor activity(GO:0032395)
4.2 12.7 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
4.1 16.3 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
3.7 11.1 GO:0004878 complement component C5a receptor activity(GO:0004878)
3.6 10.8 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
3.5 17.4 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
3.4 17.0 GO:0047820 D-glutamate cyclase activity(GO:0047820)
3.2 9.7 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
3.2 9.5 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
3.1 48.8 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
3.0 3.0 GO:0042806 fucose binding(GO:0042806)
3.0 11.9 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
2.9 23.2 GO:0019763 immunoglobulin receptor activity(GO:0019763)
2.9 77.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
2.8 11.3 GO:0005124 scavenger receptor binding(GO:0005124)
2.8 16.7 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
2.6 10.4 GO:0047708 biotinidase activity(GO:0047708)
2.6 17.9 GO:0030369 ICAM-3 receptor activity(GO:0030369)
2.6 7.7 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
2.5 20.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
2.5 44.2 GO:0005522 profilin binding(GO:0005522)
2.4 9.7 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
2.4 9.5 GO:0030492 hemoglobin binding(GO:0030492)
2.4 7.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
2.3 9.4 GO:0032406 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
2.2 15.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
2.1 42.9 GO:0070016 armadillo repeat domain binding(GO:0070016)
2.1 23.6 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
2.1 8.6 GO:0004803 transposase activity(GO:0004803)
2.1 10.6 GO:0004906 interferon-gamma receptor activity(GO:0004906)
2.1 8.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
2.1 6.2 GO:0051787 misfolded protein binding(GO:0051787)
2.1 10.3 GO:0004668 protein-arginine deiminase activity(GO:0004668)
2.0 26.6 GO:0005344 oxygen transporter activity(GO:0005344)
2.0 8.1 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
2.0 8.0 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
2.0 5.9 GO:0032184 SUMO polymer binding(GO:0032184)
1.9 7.8 GO:0005502 11-cis retinal binding(GO:0005502)
1.9 3.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
1.9 7.6 GO:0043515 kinetochore binding(GO:0043515)
1.9 18.9 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
1.9 15.1 GO:0004565 beta-galactosidase activity(GO:0004565)
1.9 7.4 GO:0042903 tubulin deacetylase activity(GO:0042903)
1.9 22.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
1.8 5.4 GO:0030158 protein xylosyltransferase activity(GO:0030158)
1.8 26.7 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
1.7 13.9 GO:0004875 complement receptor activity(GO:0004875)
1.7 10.4 GO:0042610 CD8 receptor binding(GO:0042610)
1.7 48.2 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
1.7 5.1 GO:1904599 advanced glycation end-product binding(GO:1904599)
1.7 10.2 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
1.7 13.6 GO:0005534 galactose binding(GO:0005534)
1.7 6.8 GO:0017040 ceramidase activity(GO:0017040)
1.6 16.4 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
1.6 8.0 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
1.6 22.1 GO:0033691 sialic acid binding(GO:0033691)
1.6 25.0 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
1.5 318.4 GO:0003823 antigen binding(GO:0003823)
1.5 15.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
1.5 4.5 GO:0032794 GTPase activating protein binding(GO:0032794)
1.5 7.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
1.5 4.4 GO:0005137 interleukin-5 receptor binding(GO:0005137)
1.4 4.3 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
1.4 2.8 GO:0042289 MHC class II protein binding(GO:0042289)
1.4 16.7 GO:0019864 IgG binding(GO:0019864)
1.4 8.3 GO:0004882 androgen receptor activity(GO:0004882)
1.4 6.9 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
1.4 4.1 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
1.4 4.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
1.3 18.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
1.3 3.9 GO:0005174 CD40 receptor binding(GO:0005174)
1.3 5.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
1.3 3.9 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
1.3 6.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
1.3 15.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
1.2 4.9 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
1.2 5.9 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
1.2 3.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
1.2 37.0 GO:0043014 alpha-tubulin binding(GO:0043014)
1.1 10.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
1.1 6.7 GO:0061649 ubiquitinated histone binding(GO:0061649)
1.1 5.5 GO:0030348 syntaxin-3 binding(GO:0030348)
1.1 9.8 GO:0032051 clathrin light chain binding(GO:0032051)
1.1 21.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
1.1 18.0 GO:0043274 phospholipase binding(GO:0043274)
1.0 8.3 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
1.0 20.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
1.0 5.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.0 12.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
1.0 1.0 GO:0050072 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) m7G(5')pppN diphosphatase activity(GO:0050072) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
1.0 3.0 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
1.0 25.2 GO:0016805 dipeptidase activity(GO:0016805)
1.0 2.9 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
1.0 1.9 GO:0015057 thrombin receptor activity(GO:0015057)
1.0 5.7 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.9 6.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.9 2.8 GO:0035276 ethanol binding(GO:0035276)
0.9 38.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.9 4.5 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.9 8.9 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.9 3.5 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.9 9.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.9 20.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.9 13.7 GO:0004707 MAP kinase activity(GO:0004707)
0.9 16.2 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.8 4.2 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.8 6.7 GO:1903136 cuprous ion binding(GO:1903136)
0.8 7.5 GO:0048495 Roundabout binding(GO:0048495)
0.8 5.8 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.8 4.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.8 1.6 GO:0097108 hedgehog family protein binding(GO:0097108)
0.8 61.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.8 3.9 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.8 3.9 GO:0043532 angiostatin binding(GO:0043532)
0.8 3.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.8 2.3 GO:0015616 DNA translocase activity(GO:0015616)
0.7 1.5 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) uptake transmembrane transporter activity(GO:0015563) azole transmembrane transporter activity(GO:1901474)
0.7 2.9 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.7 4.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.7 5.6 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.7 2.8 GO:0019862 IgA binding(GO:0019862)
0.7 2.7 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.7 16.9 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.7 4.7 GO:0008142 oxysterol binding(GO:0008142)
0.7 3.3 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.7 8.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.7 3.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.7 3.3 GO:0032393 MHC class I receptor activity(GO:0032393)
0.7 7.3 GO:0031419 cobalamin binding(GO:0031419)
0.7 2.7 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.7 6.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.7 4.6 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.7 27.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.6 2.6 GO:0035473 lipase binding(GO:0035473)
0.6 143.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.6 16.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.6 10.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.6 1.9 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.6 6.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.6 4.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.6 7.9 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.6 4.8 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.6 12.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.6 11.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.6 5.9 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.6 83.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.6 7.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.6 2.9 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.6 1.2 GO:1990254 keratin filament binding(GO:1990254)
0.6 1.7 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.6 7.5 GO:0008517 folic acid transporter activity(GO:0008517)
0.6 4.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.6 1.1 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.6 12.6 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.6 5.6 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.6 5.0 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.5 2.7 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.5 7.0 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.5 1.6 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.5 2.7 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.5 6.9 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.5 5.8 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.5 6.6 GO:0008199 ferric iron binding(GO:0008199)
0.5 3.0 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.5 3.0 GO:0004522 ribonuclease A activity(GO:0004522)
0.5 10.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.5 5.0 GO:0042834 peptidoglycan binding(GO:0042834)
0.5 15.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.5 7.9 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.5 14.1 GO:0001671 ATPase activator activity(GO:0001671)
0.5 7.7 GO:0050681 androgen receptor binding(GO:0050681)
0.5 8.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.5 34.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.5 37.5 GO:0001618 virus receptor activity(GO:0001618)
0.5 4.8 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.5 3.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.5 1.4 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.5 2.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.5 5.9 GO:0051011 microtubule minus-end binding(GO:0051011)
0.5 5.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.4 3.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.4 2.7 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.4 9.7 GO:0048487 beta-tubulin binding(GO:0048487)
0.4 1.3 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.4 22.0 GO:0015485 cholesterol binding(GO:0015485)
0.4 6.1 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.4 9.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.4 9.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.4 3.6 GO:0005542 folic acid binding(GO:0005542)
0.4 13.4 GO:0005158 insulin receptor binding(GO:0005158)
0.4 1.6 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.4 1.6 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.4 1.5 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.4 3.8 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.4 1.5 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.4 6.3 GO:0038191 neuropilin binding(GO:0038191)
0.4 2.9 GO:1901612 cardiolipin binding(GO:1901612)
0.4 2.2 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.4 10.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.4 6.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.4 8.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.3 3.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.3 3.8 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.3 2.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.3 3.8 GO:0045499 chemorepellent activity(GO:0045499)
0.3 7.8 GO:0017091 AU-rich element binding(GO:0017091)
0.3 2.3 GO:0016866 intramolecular transferase activity(GO:0016866)
0.3 12.9 GO:0036002 pre-mRNA binding(GO:0036002)
0.3 2.6 GO:0019199 transmembrane receptor protein kinase activity(GO:0019199)
0.3 1.3 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.3 8.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 17.9 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.3 3.4 GO:0003951 NAD+ kinase activity(GO:0003951)
0.3 2.2 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.3 1.9 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.3 5.1 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.3 1.5 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.3 10.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.3 5.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.3 2.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.3 2.0 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.3 9.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.3 4.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.3 0.6 GO:0030957 Tat protein binding(GO:0030957)
0.3 12.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.3 10.9 GO:0070412 R-SMAD binding(GO:0070412)
0.3 1.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.3 1.9 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.3 5.1 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.3 7.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.3 7.1 GO:0005123 death receptor binding(GO:0005123)
0.3 4.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.3 2.8 GO:0036122 BMP binding(GO:0036122)
0.3 93.1 GO:0030695 GTPase regulator activity(GO:0030695)
0.2 1.0 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.2 2.4 GO:0050700 CARD domain binding(GO:0050700)
0.2 0.7 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.2 1.0 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 0.5 GO:0016015 morphogen activity(GO:0016015)
0.2 16.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 8.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.2 0.9 GO:0000405 bubble DNA binding(GO:0000405)
0.2 1.6 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 3.4 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.2 3.6 GO:0016405 CoA-ligase activity(GO:0016405)
0.2 3.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.2 0.9 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.2 2.9 GO:0019825 oxygen binding(GO:0019825)
0.2 1.1 GO:0016918 retinal binding(GO:0016918)
0.2 3.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.2 1.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 1.7 GO:0034711 inhibin binding(GO:0034711)
0.2 3.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.2 2.1 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.2 13.6 GO:0047485 protein N-terminus binding(GO:0047485)
0.2 1.0 GO:0031782 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.2 18.7 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.2 1.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 0.6 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.2 8.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.2 2.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.2 2.5 GO:0050811 GABA receptor binding(GO:0050811)
0.2 3.0 GO:0097109 neuroligin family protein binding(GO:0097109)
0.2 1.3 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 1.6 GO:0004985 opioid receptor activity(GO:0004985)
0.2 1.1 GO:0017018 myosin phosphatase activity(GO:0017018)
0.2 1.1 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.2 4.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 2.8 GO:0034979 NAD-dependent protein deacetylase activity(GO:0034979)
0.2 1.8 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.2 2.3 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.2 16.7 GO:0003682 chromatin binding(GO:0003682)
0.2 4.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2 3.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 3.7 GO:0070402 NADPH binding(GO:0070402)
0.2 1.2 GO:0015232 heme transporter activity(GO:0015232)
0.2 3.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.2 1.0 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.2 1.6 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 1.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.2 1.7 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.2 1.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 2.0 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 2.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 2.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 2.7 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.1 13.3 GO:0005057 receptor signaling protein activity(GO:0005057)
0.1 0.7 GO:0005319 lipid transporter activity(GO:0005319)
0.1 3.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 1.8 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.1 0.4 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 19.4 GO:0004871 signal transducer activity(GO:0004871)
0.1 2.1 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 2.2 GO:0005506 iron ion binding(GO:0005506)
0.1 1.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 2.3 GO:0031005 filamin binding(GO:0031005)
0.1 2.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 2.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 11.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 3.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 14.3 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820)
0.1 2.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 5.0 GO:0030507 spectrin binding(GO:0030507)
0.1 0.9 GO:0016778 diphosphotransferase activity(GO:0016778)
0.1 0.8 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.8 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 0.5 GO:0005499 vitamin D binding(GO:0005499)
0.1 2.0 GO:0002162 dystroglycan binding(GO:0002162)
0.1 2.0 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 4.3 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 3.7 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 2.2 GO:0008066 glutamate receptor activity(GO:0008066)
0.1 1.0 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.8 GO:0042169 SH2 domain binding(GO:0042169)
0.1 2.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.0 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 0.2 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 1.1 GO:0031014 troponin T binding(GO:0031014)
0.1 3.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 5.6 GO:0005262 calcium channel activity(GO:0005262)
0.1 0.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 6.2 GO:0044325 ion channel binding(GO:0044325)
0.1 1.2 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 2.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 2.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 0.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.5 GO:0019841 retinol binding(GO:0019841)
0.1 1.2 GO:0071949 FAD binding(GO:0071949)
0.1 1.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
0.1 1.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 1.0 GO:0005521 lamin binding(GO:0005521)
0.0 5.7 GO:0008565 protein transporter activity(GO:0008565)
0.0 2.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.3 GO:0055103 ligase regulator activity(GO:0055103)
0.0 0.6 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.6 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 3.8 GO:0005179 hormone activity(GO:0005179)
0.0 0.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.6 GO:0008483 transaminase activity(GO:0008483)
0.0 0.2 GO:0005372 water transmembrane transporter activity(GO:0005372)
0.0 1.4 GO:0070035 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.2 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.5 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 2.0 GO:0051020 GTPase binding(GO:0051020)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 76.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
2.1 14.9 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
1.9 194.6 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
1.6 66.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
1.6 17.6 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
1.4 2.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
1.4 45.5 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
1.4 11.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
1.4 26.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
1.4 43.9 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
1.2 28.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
1.1 68.7 PID BCR 5PATHWAY BCR signaling pathway
1.0 38.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.9 4.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.9 3.7 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.9 27.7 ST GAQ PATHWAY G alpha q Pathway
0.9 12.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.9 4.4 PID IL5 PATHWAY IL5-mediated signaling events
0.9 35.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.9 36.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.8 57.7 PID IL12 2PATHWAY IL12-mediated signaling events
0.8 19.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.8 6.8 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.7 9.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.7 27.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.7 12.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.7 12.6 ST GA12 PATHWAY G alpha 12 Pathway
0.7 17.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.6 27.5 PID ARF6 PATHWAY Arf6 signaling events
0.6 3.8 PID S1P S1P1 PATHWAY S1P1 pathway
0.6 20.9 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.6 2.8 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.5 7.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.5 2.6 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.5 45.5 PID CMYB PATHWAY C-MYB transcription factor network
0.5 44.9 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.5 9.6 PID ARF 3PATHWAY Arf1 pathway
0.5 23.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.5 23.9 PID LKB1 PATHWAY LKB1 signaling events
0.4 3.9 ST GA13 PATHWAY G alpha 13 Pathway
0.4 6.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.4 6.8 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.4 72.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.4 10.6 PID FAS PATHWAY FAS (CD95) signaling pathway
0.4 6.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.4 5.5 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.4 9.5 PID INSULIN PATHWAY Insulin Pathway
0.4 20.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.4 4.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.4 12.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.4 37.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.4 21.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.4 12.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.4 21.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.3 11.0 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.3 2.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3 4.5 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.3 15.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.3 9.5 PID TNF PATHWAY TNF receptor signaling pathway
0.3 7.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.3 3.0 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.3 4.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.3 3.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.3 4.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.2 2.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2 8.0 PID AP1 PATHWAY AP-1 transcription factor network
0.2 2.9 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.2 17.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.2 65.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.2 3.3 PID SHP2 PATHWAY SHP2 signaling
0.2 1.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 2.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 2.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 4.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 3.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 1.4 PID ALK2 PATHWAY ALK2 signaling events
0.1 5.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 1.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 0.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 1.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 18.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.6 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.2 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 157.8 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
3.6 97.9 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
3.3 68.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
2.4 66.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
2.3 65.5 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
1.6 8.2 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
1.6 100.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
1.5 124.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
1.4 4.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
1.4 18.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
1.4 25.2 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
1.4 9.7 REACTOME BETA DEFENSINS Genes involved in Beta defensins
1.4 29.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
1.3 51.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
1.3 29.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
1.3 42.7 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
1.1 16.9 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
1.0 46.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
1.0 27.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.9 8.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.9 16.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.9 69.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.8 24.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.8 23.7 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.8 16.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.8 14.7 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.8 13.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.8 21.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.7 13.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.7 26.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.7 13.6 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.7 10.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.7 18.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.6 3.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.6 31.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.6 7.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.6 4.5 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.6 8.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.6 11.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.5 6.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.5 11.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.5 13.8 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.4 5.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.4 3.9 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.4 8.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.4 5.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.4 7.4 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.4 67.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.4 8.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.4 5.0 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.4 13.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.4 4.5 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.4 12.6 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.4 15.1 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.4 49.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.3 2.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.3 8.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.3 9.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 7.5 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.3 10.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.3 12.4 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.3 3.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.3 4.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.3 3.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.3 3.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.3 7.6 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.3 3.5 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.3 4.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.3 1.8 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.3 3.1 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.2 8.2 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.2 3.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.2 8.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.2 3.9 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 14.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.2 4.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 4.8 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.2 6.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 2.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 5.4 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.2 10.4 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.2 15.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 1.6 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.2 2.6 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.2 4.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 3.9 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.2 2.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 3.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 2.9 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 3.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 5.8 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 4.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 3.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 5.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 3.3 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.1 2.4 REACTOME SIGNALING BY FGFR IN DISEASE Genes involved in Signaling by FGFR in disease
0.1 1.7 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 1.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 0.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 5.6 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.9 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.1 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 1.7 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 2.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 2.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 0.7 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 1.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 3.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 5.0 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.1 0.9 REACTOME METABOLISM OF MRNA Genes involved in Metabolism of mRNA
0.0 4.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.4 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 1.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins