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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for SMAD3

Z-value: 0.79

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Transcription factors associated with SMAD3

Gene Symbol Gene ID Gene Info
SMAD3
ENSG00000166949.11 SMAD family member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMAD3hg19_v2_chr15_+_67358163_67358192-0.308.3e-06Click!

Activity profile of SMAD3 motif

Sorted Z-values of SMAD3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_27114861 9.23 ENST00000377459.1
HIST1H2AH
histone cluster 1, H2ah
chr2_-_220110111 8.06 ENST00000428427.1
ENST00000356283.3
ENST00000432839.1
ENST00000424620.1
GLB1L
galactosidase, beta 1-like
chr2_-_220110187 7.79 ENST00000295759.7
ENST00000392089.2
GLB1L
galactosidase, beta 1-like
chr10_-_90712520 6.80 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr19_-_11688447 6.58 ENST00000590420.1
ACP5
acid phosphatase 5, tartrate resistant
chr22_-_36013368 6.25 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB
myoglobin
chr15_-_83316254 6.12 ENST00000567678.1
ENST00000450751.2
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr6_-_27782548 6.08 ENST00000333151.3
HIST1H2AJ
histone cluster 1, H2aj
chr3_+_12838161 6.02 ENST00000456430.2
CAND2
cullin-associated and neddylation-dissociated 2 (putative)
chr3_+_125687987 5.93 ENST00000514116.1
ENST00000251776.4
ENST00000504401.1
ENST00000513830.1
ENST00000508088.1
ROPN1B
rhophilin associated tail protein 1B
chr14_+_93389425 5.92 ENST00000216492.5
ENST00000334654.4
CHGA
chromogranin A (parathyroid secretory protein 1)
chr6_+_27775899 5.88 ENST00000358739.3
HIST1H2AI
histone cluster 1, H2ai
chr3_-_123710893 5.45 ENST00000467907.1
ENST00000459660.1
ENST00000495093.1
ENST00000460743.1
ENST00000405845.3
ENST00000484329.1
ENST00000479867.1
ENST00000496145.1
ROPN1
rhophilin associated tail protein 1
chr19_-_11688500 5.05 ENST00000433365.2
ACP5
acid phosphatase 5, tartrate resistant
chr1_-_9129735 4.92 ENST00000377424.4
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr15_-_83316711 4.88 ENST00000568128.1
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr4_+_55524085 4.88 ENST00000412167.2
ENST00000288135.5
KIT
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr6_-_27100529 4.78 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
HIST1H2BJ
histone cluster 1, H2bj
chr6_-_27775694 4.73 ENST00000377401.2
HIST1H2BL
histone cluster 1, H2bl
chr17_+_30813576 4.69 ENST00000313401.3
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr7_+_139529040 4.68 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr14_+_91580732 4.64 ENST00000519019.1
ENST00000523816.1
ENST00000517518.1
C14orf159
chromosome 14 open reading frame 159
chr7_+_139528952 4.61 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr14_+_91580777 4.59 ENST00000525393.2
ENST00000428926.2
ENST00000517362.1
C14orf159
chromosome 14 open reading frame 159
chr19_+_51728316 4.58 ENST00000436584.2
ENST00000421133.2
ENST00000391796.3
ENST00000262262.4
CD33
CD33 molecule
chr6_-_11807277 4.44 ENST00000379415.2
ADTRP
androgen-dependent TFPI-regulating protein
chr15_-_83316087 4.32 ENST00000568757.1
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr14_+_91580708 4.26 ENST00000518868.1
C14orf159
chromosome 14 open reading frame 159
chr12_-_110939870 4.16 ENST00000447578.2
ENST00000546588.1
ENST00000360579.7
ENST00000549970.1
ENST00000549578.1
VPS29
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr6_+_27100811 4.16 ENST00000359193.2
HIST1H2AG
histone cluster 1, H2ag
chr6_+_292051 4.15 ENST00000344450.5
DUSP22
dual specificity phosphatase 22
chr14_+_91580357 4.04 ENST00000298858.4
ENST00000521081.1
ENST00000520328.1
ENST00000256324.10
ENST00000524232.1
ENST00000522170.1
ENST00000519950.1
ENST00000523879.1
ENST00000521077.2
ENST00000518665.2
C14orf159
chromosome 14 open reading frame 159
chr6_-_27114577 3.98 ENST00000356950.1
ENST00000396891.4
HIST1H2BK
histone cluster 1, H2bk
chr11_-_72145426 3.91 ENST00000535990.1
ENST00000437826.2
ENST00000340729.5
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr14_+_91581011 3.90 ENST00000523894.1
ENST00000522322.1
ENST00000523771.1
C14orf159
chromosome 14 open reading frame 159
chr16_+_30483962 3.87 ENST00000356798.6
ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr1_-_156399184 3.65 ENST00000368243.1
ENST00000357975.4
ENST00000310027.5
ENST00000400991.2
C1orf61
chromosome 1 open reading frame 61
chr19_+_42724423 3.56 ENST00000301215.3
ENST00000597945.1
ZNF526
zinc finger protein 526
chr6_-_26216872 3.43 ENST00000244601.3
HIST1H2BG
histone cluster 1, H2bg
chr6_-_26189304 3.42 ENST00000340756.2
HIST1H4D
histone cluster 1, H4d
chr14_-_24551137 3.37 ENST00000396995.1
NRL
neural retina leucine zipper
chr15_+_81591757 3.36 ENST00000558332.1
IL16
interleukin 16
chr6_+_27806319 3.35 ENST00000606613.1
ENST00000396980.3
HIST1H2BN
histone cluster 1, H2bn
chr18_+_29598335 3.33 ENST00000217740.3
RNF125
ring finger protein 125, E3 ubiquitin protein ligase
chr6_+_27782788 3.19 ENST00000359465.4
HIST1H2BM
histone cluster 1, H2bm
chr6_+_26204825 3.15 ENST00000360441.4
HIST1H4E
histone cluster 1, H4e
chr16_+_30484021 3.14 ENST00000358164.5
ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr1_-_9129598 3.06 ENST00000535586.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr11_+_113258495 3.04 ENST00000303941.3
ANKK1
ankyrin repeat and kinase domain containing 1
chr1_-_160832642 3.04 ENST00000368034.4
CD244
CD244 molecule, natural killer cell receptor 2B4
chr6_+_27791862 3.04 ENST00000355057.1
HIST1H4J
histone cluster 1, H4j
chr22_+_41956767 2.98 ENST00000306149.7
CSDC2
cold shock domain containing C2, RNA binding
chr13_-_114898016 2.94 ENST00000542651.1
ENST00000334062.7
RASA3
RAS p21 protein activator 3
chr10_+_94451574 2.94 ENST00000492654.2
HHEX
hematopoietically expressed homeobox
chr2_+_204732666 2.92 ENST00000295854.6
ENST00000472206.1
CTLA4
cytotoxic T-lymphocyte-associated protein 4
chr1_+_66797687 2.90 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr1_-_8877692 2.88 ENST00000400908.2
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr12_-_9913489 2.86 ENST00000228434.3
ENST00000536709.1
CD69
CD69 molecule
chr3_+_51741072 2.76 ENST00000395052.3
GRM2
glutamate receptor, metabotropic 2
chr14_-_24551195 2.70 ENST00000560550.1
NRL
neural retina leucine zipper
chr18_+_13612613 2.61 ENST00000586765.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr12_+_26111823 2.59 ENST00000381352.3
ENST00000535907.1
ENST00000405154.2
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr6_+_26124373 2.53 ENST00000377791.2
ENST00000602637.1
HIST1H2AC
histone cluster 1, H2ac
chr20_+_24449821 2.53 ENST00000376862.3
SYNDIG1
synapse differentiation inducing 1
chr19_-_36304201 2.51 ENST00000301175.3
PRODH2
proline dehydrogenase (oxidase) 2
chr6_+_26217159 2.47 ENST00000303910.2
HIST1H2AE
histone cluster 1, H2ae
chr7_+_50348268 2.42 ENST00000438033.1
ENST00000439701.1
IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr2_+_16080659 2.36 ENST00000281043.3
MYCN
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr20_-_43280325 2.32 ENST00000537820.1
ADA
adenosine deaminase
chr20_-_43280361 2.25 ENST00000372874.4
ADA
adenosine deaminase
chr20_-_23030296 2.23 ENST00000377103.2
THBD
thrombomodulin
chr1_-_226129083 2.20 ENST00000420304.2
LEFTY2
left-right determination factor 2
chr16_-_84220633 2.17 ENST00000566732.1
ENST00000561955.1
ENST00000564454.1
ENST00000341690.6
ENST00000541676.1
ENST00000570117.1
ENST00000564345.1
TAF1C
TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
chrX_-_153523462 2.15 ENST00000361930.3
ENST00000369926.1
TEX28
testis expressed 28
chr4_-_39033963 2.14 ENST00000381938.3
TMEM156
transmembrane protein 156
chr17_-_39093672 2.13 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr5_-_180242534 2.06 ENST00000333055.3
ENST00000513431.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr4_-_186696425 2.06 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2
sorbin and SH3 domain containing 2
chr2_+_204732487 2.06 ENST00000302823.3
CTLA4
cytotoxic T-lymphocyte-associated protein 4
chr6_+_146920097 2.05 ENST00000397944.3
ENST00000522242.1
ADGB
androglobin
chr16_-_20681177 2.03 ENST00000524149.1
ACSM1
acyl-CoA synthetase medium-chain family member 1
chr15_+_71184931 2.02 ENST00000560369.1
ENST00000260382.5
LRRC49
leucine rich repeat containing 49
chr6_-_27860956 2.02 ENST00000359611.2
HIST1H2AM
histone cluster 1, H2am
chr12_+_65563329 1.99 ENST00000308330.2
LEMD3
LEM domain containing 3
chrX_-_110513703 1.98 ENST00000324068.1
CAPN6
calpain 6
chr9_+_21967137 1.95 ENST00000441769.2
C9orf53
chromosome 9 open reading frame 53
chr19_-_55691472 1.95 ENST00000537500.1
SYT5
synaptotagmin V
chr11_+_66406149 1.94 ENST00000578778.1
ENST00000483858.1
ENST00000398692.4
ENST00000510173.2
ENST00000506523.2
ENST00000530235.1
ENST00000532968.1
RBM4
RNA binding motif protein 4
chr11_+_116700614 1.93 ENST00000375345.1
APOC3
apolipoprotein C-III
chr8_+_38585704 1.91 ENST00000519416.1
ENST00000520615.1
TACC1
transforming, acidic coiled-coil containing protein 1
chr4_+_2814011 1.88 ENST00000502260.1
ENST00000435136.2
SH3BP2
SH3-domain binding protein 2
chr1_+_149804218 1.86 ENST00000610125.1
HIST2H4A
histone cluster 2, H4a
chr11_-_133402410 1.85 ENST00000524381.1
OPCML
opioid binding protein/cell adhesion molecule-like
chr17_-_3195876 1.83 ENST00000323404.1
OR3A1
olfactory receptor, family 3, subfamily A, member 1
chr19_-_55691614 1.81 ENST00000592470.1
ENST00000354308.3
SYT5
synaptotagmin V
chr16_-_84220604 1.77 ENST00000567759.1
TAF1C
TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
chr11_+_116700600 1.76 ENST00000227667.3
APOC3
apolipoprotein C-III
chr2_+_220110177 1.72 ENST00000409638.3
ENST00000396738.2
ENST00000409516.3
STK16
serine/threonine kinase 16
chr6_+_146920116 1.65 ENST00000367493.3
ADGB
androglobin
chr6_-_27806117 1.65 ENST00000330180.2
HIST1H2AK
histone cluster 1, H2ak
chr2_-_136594740 1.61 ENST00000264162.2
LCT
lactase
chr6_-_41888843 1.60 ENST00000434077.1
ENST00000409312.1
MED20
mediator complex subunit 20
chr11_+_60869867 1.56 ENST00000347785.3
CD5
CD5 molecule
chr9_-_34691201 1.56 ENST00000378800.3
ENST00000311925.2
CCL19
chemokine (C-C motif) ligand 19
chr1_-_226129189 1.53 ENST00000366820.5
LEFTY2
left-right determination factor 2
chr2_-_208031943 1.51 ENST00000421199.1
ENST00000457962.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr4_-_90759440 1.49 ENST00000336904.3
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr14_+_102786063 1.43 ENST00000442396.2
ENST00000262236.5
ZNF839
zinc finger protein 839
chr6_-_26027480 1.43 ENST00000377364.3
HIST1H4B
histone cluster 1, H4b
chr1_+_25757376 1.36 ENST00000399766.3
ENST00000399763.3
ENST00000374343.4
TMEM57
transmembrane protein 57
chr19_-_46148820 1.35 ENST00000587152.1
EML2
echinoderm microtubule associated protein like 2
chr7_+_39125365 1.34 ENST00000559001.1
ENST00000464276.2
POU6F2
POU class 6 homeobox 2
chr9_+_5890802 1.33 ENST00000381477.3
ENST00000381476.1
ENST00000381471.1
MLANA
melan-A
chr11_+_62538775 1.32 ENST00000294168.3
ENST00000526261.1
TAF6L
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
chr18_+_43753974 1.27 ENST00000282059.6
ENST00000321319.6
C18orf25
chromosome 18 open reading frame 25
chr11_+_72983246 1.24 ENST00000393590.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr5_-_127674883 1.23 ENST00000507835.1
FBN2
fibrillin 2
chr4_+_2813946 1.22 ENST00000442312.2
SH3BP2
SH3-domain binding protein 2
chr6_-_26033796 1.20 ENST00000259791.2
HIST1H2AB
histone cluster 1, H2ab
chr6_-_46922659 1.19 ENST00000265417.7
GPR116
G protein-coupled receptor 116
chr19_+_41594377 1.17 ENST00000330436.3
CYP2A13
cytochrome P450, family 2, subfamily A, polypeptide 13
chr6_+_27861190 1.15 ENST00000303806.4
HIST1H2BO
histone cluster 1, H2bo
chr19_-_55691377 1.14 ENST00000589172.1
SYT5
synaptotagmin V
chr16_-_3306587 1.14 ENST00000541159.1
ENST00000536379.1
ENST00000219596.1
ENST00000339854.4
MEFV
Mediterranean fever
chr6_+_26273144 1.08 ENST00000377733.2
HIST1H2BI
histone cluster 1, H2bi
chr8_+_10530155 1.02 ENST00000521818.1
C8orf74
chromosome 8 open reading frame 74
chr16_-_15180257 1.02 ENST00000540462.1
RRN3
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr4_-_38666430 1.00 ENST00000436901.1
AC021860.1
Uncharacterized protein
chr14_+_96858454 0.96 ENST00000555570.1
AK7
adenylate kinase 7
chr18_+_77623668 0.93 ENST00000316249.3
KCNG2
potassium voltage-gated channel, subfamily G, member 2
chr11_+_124824000 0.92 ENST00000529051.1
ENST00000344762.5
CCDC15
coiled-coil domain containing 15
chr18_+_13611763 0.89 ENST00000585931.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr3_+_190105909 0.82 ENST00000456423.1
CLDN16
claudin 16
chr5_+_79950463 0.80 ENST00000265081.6
MSH3
mutS homolog 3
chr6_-_41888814 0.78 ENST00000409060.1
ENST00000265350.4
MED20
mediator complex subunit 20
chr19_+_36132631 0.77 ENST00000379026.2
ENST00000379023.4
ENST00000402764.2
ENST00000479824.1
ETV2
ets variant 2
chr20_-_60795316 0.75 ENST00000317393.6
HRH3
histamine receptor H3
chr1_-_9189229 0.75 ENST00000377411.4
GPR157
G protein-coupled receptor 157
chr5_-_68628543 0.72 ENST00000396496.2
ENST00000511257.1
ENST00000383374.2
CCDC125
coiled-coil domain containing 125
chr9_+_136399929 0.69 ENST00000393060.1
ADAMTSL2
ADAMTS-like 2
chr1_+_52682052 0.69 ENST00000371591.1
ZFYVE9
zinc finger, FYVE domain containing 9
chr1_-_9129631 0.68 ENST00000377414.3
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr1_-_160040038 0.62 ENST00000368089.3
KCNJ10
potassium inwardly-rectifying channel, subfamily J, member 10
chrX_-_2847366 0.60 ENST00000381154.1
ARSD
arylsulfatase D
chrX_-_46618490 0.56 ENST00000328306.4
SLC9A7
solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
chrX_-_48931648 0.56 ENST00000376386.3
ENST00000376390.4
PRAF2
PRA1 domain family, member 2
chr6_-_26124138 0.53 ENST00000314332.5
ENST00000396984.1
HIST1H2BC
histone cluster 1, H2bc
chr11_+_46383121 0.53 ENST00000454345.1
DGKZ
diacylglycerol kinase, zeta
chr4_+_40337340 0.47 ENST00000310169.2
CHRNA9
cholinergic receptor, nicotinic, alpha 9 (neuronal)
chr15_-_26874230 0.46 ENST00000400188.3
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr12_+_14927270 0.45 ENST00000544848.1
H2AFJ
H2A histone family, member J
chr2_-_49381646 0.45 ENST00000346173.3
ENST00000406846.2
FSHR
follicle stimulating hormone receptor
chr4_-_26492076 0.40 ENST00000295589.3
CCKAR
cholecystokinin A receptor
chr16_-_425205 0.38 ENST00000448854.1
TMEM8A
transmembrane protein 8A
chr2_-_49381572 0.36 ENST00000454032.1
ENST00000304421.4
FSHR
follicle stimulating hormone receptor
chrX_+_49832231 0.36 ENST00000376108.3
CLCN5
chloride channel, voltage-sensitive 5
chr7_-_142247606 0.33 ENST00000390361.3
TRBV7-3
T cell receptor beta variable 7-3
chr1_+_59762642 0.33 ENST00000371218.4
ENST00000303721.7
FGGY
FGGY carbohydrate kinase domain containing
chr11_+_117070037 0.30 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
TAGLN
transgelin
chr19_-_51192661 0.30 ENST00000391813.1
SHANK1
SH3 and multiple ankyrin repeat domains 1
chr4_+_186990298 0.25 ENST00000296795.3
ENST00000513189.1
TLR3
toll-like receptor 3
chr7_-_14942944 0.24 ENST00000403951.2
DGKB
diacylglycerol kinase, beta 90kDa
chr2_-_128784846 0.16 ENST00000259235.3
ENST00000357702.5
ENST00000424298.1
SAP130
Sin3A-associated protein, 130kDa
chr5_+_140625147 0.10 ENST00000231173.3
PCDHB15
protocadherin beta 15
chr20_-_60795296 0.10 ENST00000340177.5
HRH3
histamine receptor H3
chr15_-_22473353 0.09 ENST00000557788.2
IGHV4OR15-8
immunoglobulin heavy variable 4/OR15-8 (non-functional)
chr5_+_140529630 0.05 ENST00000543635.1
PCDHB6
protocadherin beta 6

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 11.6 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
2.0 5.9 GO:2000705 dense core granule biogenesis(GO:0061110) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
1.9 15.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
1.6 4.9 GO:0048170 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) erythropoietin-mediated signaling pathway(GO:0038162) positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
1.6 4.7 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
1.5 4.6 GO:0046102 hypoxanthine salvage(GO:0043103) inosine metabolic process(GO:0046102)
1.5 6.1 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
1.2 3.7 GO:2000910 regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
1.1 6.8 GO:0090131 mesenchyme migration(GO:0090131)
1.0 3.0 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
1.0 5.0 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
1.0 2.9 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.9 6.0 GO:1990539 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.8 6.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.7 2.9 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.7 2.0 GO:0018874 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.5 23.9 GO:0006536 glutamate metabolic process(GO:0006536)
0.5 1.6 GO:2000547 dendritic cell dendrite assembly(GO:0097026) regulation of dendritic cell dendrite assembly(GO:2000547)
0.5 2.6 GO:0034334 adherens junction maintenance(GO:0034334)
0.5 9.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.5 2.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.5 7.0 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.5 2.0 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.5 9.3 GO:0002227 innate immune response in mucosa(GO:0002227)
0.4 1.3 GO:0048867 stem cell fate determination(GO:0048867)
0.4 4.4 GO:0010265 SCF complex assembly(GO:0010265)
0.4 1.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.3 5.9 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.3 3.3 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.3 1.5 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.3 3.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.3 2.5 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.3 23.6 GO:0006342 chromatin silencing(GO:0006342)
0.2 4.1 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.2 2.9 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 1.6 GO:0044245 polysaccharide digestion(GO:0044245)
0.2 0.9 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.2 2.2 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.2 0.8 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.2 1.2 GO:0009804 coumarin metabolic process(GO:0009804)
0.2 2.8 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.2 4.2 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.2 2.4 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2 0.8 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.2 3.4 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 1.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 1.4 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.1 0.4 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.1 4.9 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.1 5.0 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.1 0.6 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.1 12.4 GO:0006334 nucleosome assembly(GO:0006334)
0.1 0.3 GO:0050894 determination of affect(GO:0050894)
0.1 1.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.8 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.1 0.7 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.1 0.5 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 0.5 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 0.3 GO:0034344 microglial cell activation involved in immune response(GO:0002282) type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 3.7 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 2.1 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.8 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.1 0.7 GO:0051270 regulation of cellular component movement(GO:0051270)
0.1 0.7 GO:0060019 radial glial cell differentiation(GO:0060019)
0.1 0.7 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 2.9 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 1.8 GO:0008038 neuron recognition(GO:0008038)
0.0 1.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.6 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 2.9 GO:0035690 cellular response to drug(GO:0035690)
0.0 2.0 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 3.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.3 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.5 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.5 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.6 GO:0015813 L-glutamate transport(GO:0015813)
0.0 2.4 GO:0030218 erythrocyte differentiation(GO:0030218)
0.0 1.3 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 1.0 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 2.1 GO:0070268 cornification(GO:0070268)
0.0 1.9 GO:0021987 cerebral cortex development(GO:0021987)
0.0 1.6 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.6 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 3.0 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 1.5 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.4 GO:1903959 regulation of anion transmembrane transport(GO:1903959)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.8 GO:0030485 smooth muscle contractile fiber(GO:0030485)
1.4 4.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
1.2 4.7 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
1.2 7.0 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
0.8 4.9 GO:1990769 proximal neuron projection(GO:1990769)
0.8 15.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.8 45.3 GO:0000786 nucleosome(GO:0000786)
0.6 3.9 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.5 3.7 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.3 5.9 GO:0042583 chromaffin granule(GO:0042583)
0.3 0.8 GO:0032302 MutSbeta complex(GO:0032302)
0.2 3.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2 2.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.2 2.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 4.9 GO:0042629 mast cell granule(GO:0042629)
0.1 2.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 5.0 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.1 2.0 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 10.6 GO:0035579 specific granule membrane(GO:0035579)
0.1 1.3 GO:0030914 STAGA complex(GO:0030914)
0.1 1.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 2.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 2.4 GO:0016592 mediator complex(GO:0016592)
0.1 1.2 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 2.5 GO:0043198 dendritic shaft(GO:0043198)
0.0 5.9 GO:0031514 motile cilium(GO:0031514)
0.0 12.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.0 GO:0005876 spindle microtubule(GO:0005876)
0.0 2.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 2.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 2.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 2.1 GO:0005882 intermediate filament(GO:0005882)
0.0 2.8 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.7 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.3 GO:0036020 endolysosome membrane(GO:0036020)
0.0 26.0 GO:0005773 vacuole(GO:0005773)
0.0 1.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.0 GO:0072562 blood microparticle(GO:0072562)
0.0 1.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.9 GO:0030496 midbody(GO:0030496)
0.0 2.1 GO:0030018 Z disc(GO:0030018)
0.0 0.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.7 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.8 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.9 GO:0044306 neuron projection terminus(GO:0044306)
0.0 1.4 GO:0005875 microtubule associated complex(GO:0005875)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 21.4 GO:0047820 D-glutamate cyclase activity(GO:0047820)
3.1 9.3 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
2.0 15.8 GO:0004565 beta-galactosidase activity(GO:0004565)
1.6 4.7 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
1.0 7.0 GO:0030369 ICAM-3 receptor activity(GO:0030369)
1.0 2.9 GO:0008267 poly-glutamine tract binding(GO:0008267)
1.0 15.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.9 3.7 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.9 11.6 GO:0008199 ferric iron binding(GO:0008199)
0.9 6.0 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.6 2.5 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.6 4.6 GO:0004000 adenosine deaminase activity(GO:0004000)
0.6 2.8 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.5 2.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.5 6.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.4 1.6 GO:0008422 beta-glucosidase activity(GO:0008422)
0.4 1.6 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.3 1.0 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.3 6.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.3 1.5 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.3 4.9 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.3 0.8 GO:0000404 heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.2 2.0 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.2 3.9 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.2 1.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.2 0.8 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.2 2.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 6.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.2 0.5 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.2 1.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.2 3.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 5.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.7 GO:0050436 microfibril binding(GO:0050436)
0.1 4.8 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 0.4 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.1 2.9 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1 4.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.6 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 2.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.9 GO:0004969 histamine receptor activity(GO:0004969)
0.1 2.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 4.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 3.0 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 2.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 1.0 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 3.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 3.5 GO:0070412 R-SMAD binding(GO:0070412)
0.1 40.7 GO:0046982 protein heterodimerization activity(GO:0046982)
0.1 1.2 GO:0070330 aromatase activity(GO:0070330)
0.1 3.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.6 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 2.5 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 0.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 3.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.5 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 1.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 2.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 1.5 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 3.9 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.3 GO:0017025 TBP-class protein binding(GO:0017025)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 17.2 PID AURORA A PATHWAY Aurora A signaling
0.2 7.0 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 4.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 7.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 9.5 PID CMYB PATHWAY C-MYB transcription factor network
0.0 3.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 7.1 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 1.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 6.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 48.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.3 6.0 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 4.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 4.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.2 3.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 4.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 10.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.2 5.0 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.2 2.8 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 2.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 3.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 5.0 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 6.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 6.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 7.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 2.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 3.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.8 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 1.8 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 2.1 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 3.4 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.3 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.5 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.7 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 2.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.9 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 2.0 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation