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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for SOX11

Z-value: 0.52

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Transcription factors associated with SOX11

Gene Symbol Gene ID Gene Info
SOX11
ENSG00000176887.5 SRY-box transcription factor 11

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX11hg19_v2_chr2_+_5832799_58327990.045.2e-01Click!

Activity profile of SOX11 motif

Sorted Z-values of SOX11 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_64673630 7.69 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
KIAA0101
chrX_-_13835147 7.47 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr7_+_98923505 7.02 ENST00000432884.2
ENST00000262942.5
ARPC1A
actin related protein 2/3 complex, subunit 1A, 41kDa
chr4_-_90759440 6.67 ENST00000336904.3
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr2_-_176046391 5.40 ENST00000392541.3
ENST00000409194.1
ATP5G3
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr2_+_187371440 5.22 ENST00000445547.1
ZC3H15
zinc finger CCCH-type containing 15
chr15_+_80733570 5.19 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr3_+_69812701 4.96 ENST00000472437.1
MITF
microphthalmia-associated transcription factor
chr10_-_95242044 4.76 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
MYOF
myoferlin
chr6_-_116381918 4.66 ENST00000606080.1
FRK
fyn-related kinase
chr10_-_95241951 4.64 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
MYOF
myoferlin
chr8_-_13134045 4.59 ENST00000512044.2
DLC1
deleted in liver cancer 1
chr6_+_30585486 4.52 ENST00000259873.4
ENST00000506373.2
MRPS18B
mitochondrial ribosomal protein S18B
chr15_-_37392086 4.46 ENST00000561208.1
MEIS2
Meis homeobox 2
chr2_+_47596287 4.17 ENST00000263735.4
EPCAM
epithelial cell adhesion molecule
chr17_-_79895097 3.92 ENST00000402252.2
ENST00000583564.1
ENST00000585244.1
ENST00000337943.5
ENST00000579698.1
PYCR1
pyrroline-5-carboxylate reductase 1
chr11_-_95657231 3.90 ENST00000409459.1
ENST00000352297.7
ENST00000393223.3
ENST00000346299.5
MTMR2
myotubularin related protein 2
chr1_+_214776516 3.83 ENST00000366955.3
CENPF
centromere protein F, 350/400kDa
chr15_-_64673665 3.72 ENST00000300035.4
KIAA0101
KIAA0101
chr3_-_47950745 3.66 ENST00000429422.1
MAP4
microtubule-associated protein 4
chr17_+_6347729 3.63 ENST00000572447.1
FAM64A
family with sequence similarity 64, member A
chr11_+_12399071 3.62 ENST00000539723.1
ENST00000550549.1
PARVA
parvin, alpha
chr17_+_6347761 3.55 ENST00000250056.8
ENST00000571373.1
ENST00000570337.2
ENST00000572595.2
ENST00000576056.1
FAM64A
family with sequence similarity 64, member A
chr17_-_79895154 3.46 ENST00000405481.4
ENST00000585215.1
ENST00000577624.1
ENST00000403172.4
PYCR1
pyrroline-5-carboxylate reductase 1
chr2_-_178128250 3.03 ENST00000448782.1
ENST00000446151.2
NFE2L2
nuclear factor, erythroid 2-like 2
chr16_+_67261008 2.83 ENST00000304800.9
ENST00000563953.1
ENST00000565201.1
TMEM208
transmembrane protein 208
chr8_-_54752406 2.82 ENST00000520188.1
ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr2_-_225266743 2.56 ENST00000409685.3
FAM124B
family with sequence similarity 124B
chr2_+_109237717 2.55 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr19_+_39989535 2.45 ENST00000356433.5
DLL3
delta-like 3 (Drosophila)
chr17_-_10017864 2.27 ENST00000323816.4
GAS7
growth arrest-specific 7
chr2_-_225266711 2.26 ENST00000389874.3
FAM124B
family with sequence similarity 124B
chr4_-_170679024 2.25 ENST00000393381.2
C4orf27
chromosome 4 open reading frame 27
chr12_+_28410128 2.21 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr5_+_135496675 2.17 ENST00000507637.1
SMAD5
SMAD family member 5
chr12_+_50794592 2.13 ENST00000293618.8
ENST00000429001.3
ENST00000548174.1
ENST00000548697.1
ENST00000548993.1
ENST00000398473.2
ENST00000522085.1
ENST00000518444.1
ENST00000551886.1
LARP4
La ribonucleoprotein domain family, member 4
chr1_-_150669500 2.12 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr2_-_37068530 2.04 ENST00000593798.1
AC007382.1
Uncharacterized protein
chr5_+_140753444 2.00 ENST00000517434.1
PCDHGA6
protocadherin gamma subfamily A, 6
chr18_+_7754957 1.99 ENST00000400053.4
PTPRM
protein tyrosine phosphatase, receptor type, M
chr2_-_190044480 1.97 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr7_-_82792215 1.80 ENST00000333891.9
ENST00000423517.2
PCLO
piccolo presynaptic cytomatrix protein
chrX_+_100645812 1.78 ENST00000427805.2
ENST00000553110.3
ENST00000392994.3
ENST00000409338.1
ENST00000409170.3
RPL36A
RPL36A-HNRNPH2
ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chr7_-_56118981 1.75 ENST00000419984.2
ENST00000413218.1
ENST00000424596.1
PSPH
phosphoserine phosphatase
chr8_+_19796381 1.72 ENST00000524029.1
ENST00000522701.1
ENST00000311322.8
LPL
lipoprotein lipase
chr6_-_11779014 1.70 ENST00000229583.5
ADTRP
androgen-dependent TFPI-regulating protein
chr20_-_7921090 1.68 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr15_+_49447947 1.64 ENST00000327171.3
ENST00000560654.1
GALK2
galactokinase 2
chr6_+_26183958 1.64 ENST00000356530.3
HIST1H2BE
histone cluster 1, H2be
chr10_-_127505167 1.62 ENST00000368786.1
UROS
uroporphyrinogen III synthase
chr6_-_47277634 1.59 ENST00000296861.2
TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr3_-_133380731 1.57 ENST00000260810.5
TOPBP1
topoisomerase (DNA) II binding protein 1
chr8_+_104831554 1.57 ENST00000408894.2
RIMS2
regulating synaptic membrane exocytosis 2
chr17_-_34344991 1.55 ENST00000591423.1
CCL23
chemokine (C-C motif) ligand 23
chr1_-_205744205 1.42 ENST00000446390.2
RAB7L1
RAB7, member RAS oncogene family-like 1
chr4_+_183164574 1.41 ENST00000511685.1
TENM3
teneurin transmembrane protein 3
chrX_-_109590174 1.36 ENST00000372054.1
GNG5P2
guanine nucleotide binding protein (G protein), gamma 5 pseudogene 2
chr6_-_11779174 1.35 ENST00000379413.2
ADTRP
androgen-dependent TFPI-regulating protein
chr12_-_10955226 1.32 ENST00000240687.2
TAS2R7
taste receptor, type 2, member 7
chr3_-_107777208 1.28 ENST00000398258.3
CD47
CD47 molecule
chr1_-_115292591 1.26 ENST00000438362.2
CSDE1
cold shock domain containing E1, RNA-binding
chr14_-_36789865 1.25 ENST00000416007.4
MBIP
MAP3K12 binding inhibitory protein 1
chr5_+_148521381 1.23 ENST00000504238.1
ABLIM3
actin binding LIM protein family, member 3
chr8_+_105352050 1.20 ENST00000297581.2
DCSTAMP
dendrocyte expressed seven transmembrane protein
chr13_-_30424821 1.20 ENST00000380680.4
UBL3
ubiquitin-like 3
chr2_+_138722028 1.20 ENST00000280096.5
HNMT
histamine N-methyltransferase
chr5_+_169780485 1.16 ENST00000377360.4
KCNIP1
Kv channel interacting protein 1
chr8_+_104831472 1.14 ENST00000262231.10
ENST00000507740.1
RIMS2
regulating synaptic membrane exocytosis 2
chr14_-_36789783 1.13 ENST00000605579.1
ENST00000604336.1
ENST00000359527.7
ENST00000603139.1
ENST00000318473.7
MBIP
MAP3K12 binding inhibitory protein 1
chr1_-_24469602 1.11 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr2_+_138721850 1.11 ENST00000329366.4
ENST00000280097.3
HNMT
histamine N-methyltransferase
chr17_-_34345002 1.03 ENST00000293280.2
CCL23
chemokine (C-C motif) ligand 23
chr1_+_145524891 1.01 ENST00000369304.3
ITGA10
integrin, alpha 10
chr4_-_73434498 1.00 ENST00000286657.4
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr10_+_118350522 0.99 ENST00000530319.1
ENST00000527980.1
ENST00000471549.1
ENST00000534537.1
PNLIPRP1
pancreatic lipase-related protein 1
chr3_-_167191814 0.88 ENST00000466903.1
ENST00000264677.4
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr9_+_71986182 0.80 ENST00000303068.7
FAM189A2
family with sequence similarity 189, member A2
chr10_+_5238793 0.79 ENST00000263126.1
AKR1C4
aldo-keto reductase family 1, member C4
chr4_-_159080806 0.73 ENST00000590648.1
FAM198B
family with sequence similarity 198, member B
chr2_-_20251744 0.72 ENST00000175091.4
LAPTM4A
lysosomal protein transmembrane 4 alpha
chr7_-_122635754 0.72 ENST00000249284.2
TAS2R16
taste receptor, type 2, member 16
chr2_+_102928009 0.72 ENST00000404917.2
ENST00000447231.1
IL1RL1
interleukin 1 receptor-like 1
chr1_+_65730385 0.67 ENST00000263441.7
ENST00000395325.3
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr4_+_72204755 0.65 ENST00000512686.1
ENST00000340595.3
SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr5_+_140248518 0.65 ENST00000398640.2
PCDHA11
protocadherin alpha 11
chr11_+_57425209 0.64 ENST00000533905.1
ENST00000525602.1
ENST00000302731.4
CLP1
cleavage and polyadenylation factor I subunit 1
chr19_-_14911023 0.61 ENST00000248073.2
OR7C1
olfactory receptor, family 7, subfamily C, member 1
chr5_+_173472607 0.60 ENST00000303177.3
ENST00000519867.1
NSG2
Neuron-specific protein family member 2
chr8_+_24241789 0.59 ENST00000256412.4
ENST00000538205.1
ADAMDEC1
ADAM-like, decysin 1
chr9_-_95166841 0.58 ENST00000262551.4
OGN
osteoglycin
chr2_+_102927962 0.54 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
IL1RL1
IL18R1
interleukin 1 receptor-like 1
interleukin 18 receptor 1
chr21_-_45671014 0.53 ENST00000436357.1
DNMT3L
DNA (cytosine-5-)-methyltransferase 3-like
chr6_+_29068386 0.52 ENST00000377171.3
OR2J1
olfactory receptor, family 2, subfamily J, member 1 (gene/pseudogene)
chr6_-_49712123 0.52 ENST00000263045.4
CRISP3
cysteine-rich secretory protein 3
chr11_+_22688150 0.52 ENST00000454584.2
GAS2
growth arrest-specific 2
chr4_-_110624564 0.52 ENST00000352981.3
ENST00000265164.2
ENST00000505486.1
CASP6
caspase 6, apoptosis-related cysteine peptidase
chr14_-_20801427 0.51 ENST00000557665.1
ENST00000358932.4
ENST00000353689.4
CCNB1IP1
cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
chr6_-_49604545 0.48 ENST00000371175.4
ENST00000229810.7
RHAG
Rh-associated glycoprotein
chr4_+_71337834 0.45 ENST00000304887.5
MUC7
mucin 7, secreted
chr1_+_196621002 0.44 ENST00000367429.4
ENST00000439155.2
CFH
complement factor H
chr4_+_169013666 0.44 ENST00000359299.3
ANXA10
annexin A10
chr3_-_55001115 0.43 ENST00000493075.1
LRTM1
leucine-rich repeats and transmembrane domains 1
chr18_+_22040620 0.43 ENST00000426880.2
HRH4
histamine receptor H4
chrX_+_102192200 0.42 ENST00000218249.5
RAB40AL
RAB40A, member RAS oncogene family-like
chr18_+_22040593 0.40 ENST00000256906.4
HRH4
histamine receptor H4
chr3_+_101504200 0.39 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr20_+_35807512 0.39 ENST00000373622.5
RPN2
ribophorin II
chr11_+_120973375 0.37 ENST00000264037.2
TECTA
tectorin alpha
chr2_-_219157250 0.36 ENST00000434015.2
ENST00000444183.1
ENST00000420341.1
ENST00000453281.1
ENST00000258412.3
ENST00000440422.1
TMBIM1
transmembrane BAX inhibitor motif containing 1
chr12_-_81763127 0.36 ENST00000541017.1
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr20_-_32308028 0.36 ENST00000409299.3
ENST00000217398.3
ENST00000344022.3
PXMP4
peroxisomal membrane protein 4, 24kDa
chr8_-_25281747 0.35 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr13_-_99630233 0.30 ENST00000376460.1
ENST00000442173.1
DOCK9
dedicator of cytokinesis 9
chr17_-_10276319 0.29 ENST00000252172.4
ENST00000418404.3
MYH13
myosin, heavy chain 13, skeletal muscle
chr3_-_87325728 0.28 ENST00000350375.2
POU1F1
POU class 1 homeobox 1
chr10_-_5446786 0.28 ENST00000479328.1
ENST00000380419.3
TUBAL3
tubulin, alpha-like 3
chr4_+_110749143 0.27 ENST00000317735.4
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr8_+_41386761 0.23 ENST00000523277.2
GINS4
GINS complex subunit 4 (Sld5 homolog)
chr8_+_24241969 0.23 ENST00000522298.1
ADAMDEC1
ADAM-like, decysin 1
chr17_+_47448102 0.21 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr1_-_241799232 0.21 ENST00000366553.1
CHML
choroideremia-like (Rab escort protein 2)
chr8_-_72274095 0.20 ENST00000303824.7
EYA1
eyes absent homolog 1 (Drosophila)
chr3_-_87325612 0.18 ENST00000561167.1
ENST00000560656.1
ENST00000344265.3
POU1F1
POU class 1 homeobox 1
chr8_+_41386725 0.16 ENST00000276533.3
ENST00000520710.1
ENST00000518671.1
GINS4
GINS complex subunit 4 (Sld5 homolog)
chrX_-_32173579 0.14 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
DMD
dystrophin
chr8_+_9413410 0.12 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr1_-_120935894 0.11 ENST00000369383.4
ENST00000369384.4
FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
chr6_-_49712147 0.08 ENST00000433368.2
ENST00000354620.4
CRISP3
cysteine-rich secretory protein 3
chr14_-_92198403 0.08 ENST00000553329.1
ENST00000256343.3
CATSPERB
catsper channel auxiliary subunit beta
chr11_+_61976137 0.05 ENST00000244930.4
SCGB2A1
secretoglobin, family 2A, member 1
chr1_-_205744574 0.02 ENST00000367139.3
ENST00000235932.4
ENST00000437324.2
ENST00000414729.1
RAB7L1
RAB7, member RAS oncogene family-like 1
chr1_+_196621156 0.01 ENST00000359637.2
CFH
complement factor H

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX11

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 14.1 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.4 4.2 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
1.2 7.4 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
1.0 3.9 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.9 2.8 GO:0006624 vacuolar protein processing(GO:0006624)
0.8 2.4 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.8 9.4 GO:0001778 plasma membrane repair(GO:0001778)
0.8 3.0 GO:0043387 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.6 3.7 GO:0051012 microtubule sliding(GO:0051012)
0.5 1.6 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.5 2.0 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.4 2.4 GO:0007386 compartment pattern specification(GO:0007386)
0.4 1.6 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.4 2.3 GO:0001692 histamine metabolic process(GO:0001692)
0.4 2.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.3 4.6 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.3 1.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.3 1.2 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.3 2.7 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.3 3.8 GO:0051382 kinetochore assembly(GO:0051382)
0.2 1.7 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890) lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.2 3.6 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.2 8.2 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.2 1.3 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.2 1.7 GO:0009441 glycolate metabolic process(GO:0009441)
0.2 1.3 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.2 2.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.2 1.0 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2 0.5 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.2 7.0 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 1.7 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.4 GO:2000354 response to prolactin(GO:1990637) regulation of ovarian follicle development(GO:2000354)
0.1 0.5 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 0.8 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.7 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.6 GO:0035087 targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.1 5.0 GO:0030318 melanocyte differentiation(GO:0030318)
0.1 1.4 GO:0097264 self proteolysis(GO:0097264)
0.1 0.4 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.1 1.6 GO:0006012 galactose metabolic process(GO:0006012)
0.1 1.0 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 1.3 GO:0008228 opsonization(GO:0008228)
0.1 2.0 GO:0010842 retina layer formation(GO:0010842)
0.1 1.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.5 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 4.5 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.1 0.5 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 0.5 GO:0051026 chiasma assembly(GO:0051026)
0.1 3.9 GO:0008542 visual learning(GO:0008542)
0.1 2.3 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.4 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 2.6 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 4.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.6 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 5.2 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 1.8 GO:0035418 protein localization to synapse(GO:0035418)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.8 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 1.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.8 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 1.1 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 2.1 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.4 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 1.2 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 0.7 GO:0015701 bicarbonate transport(GO:0015701)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0005588 collagen type V trimer(GO:0005588)
0.6 2.8 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.5 3.8 GO:0097539 ciliary transition fiber(GO:0097539)
0.4 7.0 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.3 1.0 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.3 5.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2 6.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 4.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2 0.6 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.4 GO:0097679 other organism cytoplasm(GO:0097679)
0.1 2.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 1.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 14.0 GO:0005901 caveola(GO:0005901)
0.1 1.6 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 4.9 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.4 GO:0000811 GINS complex(GO:0000811)
0.1 2.2 GO:0071141 SMAD protein complex(GO:0071141)
0.1 1.7 GO:0042627 chylomicron(GO:0042627)
0.1 5.3 GO:0035580 specific granule lumen(GO:0035580)
0.1 4.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 3.7 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.6 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 2.1 GO:0005844 polysome(GO:0005844)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.7 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 2.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 4.3 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 3.6 GO:0030018 Z disc(GO:0030018)
0.0 0.5 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 2.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 3.2 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 1.6 GO:0035579 specific granule membrane(GO:0035579)
0.0 1.0 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 6.1 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
1.3 6.7 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.8 2.4 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.6 1.7 GO:0017129 triglyceride binding(GO:0017129)
0.6 1.7 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.5 1.6 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.4 1.3 GO:0002113 interleukin-33 binding(GO:0002113)
0.4 5.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.4 1.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.4 2.6 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.3 1.7 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.3 3.9 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 1.0 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 5.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 0.8 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.2 1.9 GO:0033038 bitter taste receptor activity(GO:0033038)
0.2 0.5 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.2 0.6 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.2 2.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.2 4.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 3.8 GO:0070840 dynein complex binding(GO:0070840)
0.1 2.8 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 1.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 2.4 GO:0005112 Notch binding(GO:0005112)
0.1 1.8 GO:0005522 profilin binding(GO:0005522)
0.1 5.0 GO:0070888 E-box binding(GO:0070888)
0.1 4.6 GO:0042169 SH2 domain binding(GO:0042169)
0.1 2.1 GO:0008143 poly(A) binding(GO:0008143)
0.1 3.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.6 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 4.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 1.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.4 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 7.0 GO:0051015 actin filament binding(GO:0051015)
0.0 6.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.6 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 10.4 GO:0045296 cadherin binding(GO:0045296)
0.0 0.4 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.3 GO:0000146 microfilament motor activity(GO:0000146)
0.0 8.7 GO:0005543 phospholipid binding(GO:0005543)
0.0 2.3 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.4 GO:0005123 death receptor binding(GO:0005123)
0.0 2.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 4.2 GO:0008017 microtubule binding(GO:0008017)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 1.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 4.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 PID ALK2 PATHWAY ALK2 signaling events
0.1 6.7 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 6.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 5.0 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 2.0 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 9.4 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 4.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 3.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 2.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.6 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.3 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 2.3 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.0 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.4 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.5 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 2.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.9 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.3 9.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 6.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 8.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 3.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.6 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.7 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.5 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 2.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 2.2 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane