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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for SOX3_SOX2

Z-value: 2.41

Motif logo

Transcription factors associated with SOX3_SOX2

Gene Symbol Gene ID Gene Info
ENSG00000134595.6 SRY-box transcription factor 3
ENSG00000181449.2 SRY-box transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX2hg19_v2_chr3_+_181429704_1814297220.485.6e-14Click!
SOX3hg19_v2_chrX_-_139587225_1395872340.171.3e-02Click!

Activity profile of SOX3_SOX2 motif

Sorted Z-values of SOX3_SOX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_-_74728998 148.22 ENST00000359645.3
ENST00000397875.3
ENST00000397869.3
ENST00000578193.1
ENST00000578873.1
ENST00000397866.4
ENST00000528160.1
ENST00000527041.1
ENST00000526111.1
ENST00000397865.5
ENST00000382582.3
myelin basic protein
chr14_-_60097297 91.99 ENST00000395090.1
reticulon 1
chr8_+_80523962 63.41 ENST00000518491.1
stathmin-like 2
chr14_-_60097524 59.99 ENST00000342503.4
reticulon 1
chr3_+_39509163 59.57 ENST00000436143.2
ENST00000441980.2
ENST00000311042.6
myelin-associated oligodendrocyte basic protein
chr15_+_80696666 58.05 ENST00000303329.4
aryl-hydrocarbon receptor nuclear translocator 2
chr3_+_39509070 57.34 ENST00000354668.4
ENST00000428261.1
ENST00000420739.1
ENST00000415443.1
ENST00000447324.1
ENST00000383754.3
myelin-associated oligodendrocyte basic protein
chrX_-_13956497 57.31 ENST00000398361.3
glycoprotein M6B
chr2_-_175869936 47.89 ENST00000409900.3
chimerin 1
chr11_-_117747434 47.13 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD domain containing ion transport regulator 6
chr1_+_244998602 47.10 ENST00000411948.2
COX20 cytochrome C oxidase assembly factor
chr9_+_139874683 46.14 ENST00000444903.1
prostaglandin D2 synthase 21kDa (brain)
chr8_+_26435359 41.73 ENST00000311151.5
dihydropyrimidinase-like 2
chr16_+_58497567 40.11 ENST00000258187.5
NDRG family member 4
chr8_-_18871159 40.07 ENST00000327040.8
ENST00000440756.2
pleckstrin and Sec7 domain containing 3
chr1_-_26233423 39.80 ENST00000357865.2
stathmin 1
chr5_-_146435501 38.17 ENST00000336640.6
protein phosphatase 2, regulatory subunit B, beta
chr17_-_56605341 36.63 ENST00000583114.1
septin 4
chr12_-_45270151 36.12 ENST00000429094.2
NEL-like 2 (chicken)
chr16_+_89989687 35.98 ENST00000315491.7
ENST00000555576.1
ENST00000554336.1
ENST00000553967.1
Tubulin beta-3 chain
chr5_-_146435694 35.92 ENST00000356826.3
protein phosphatase 2, regulatory subunit B, beta
chr2_-_26205340 35.22 ENST00000264712.3
kinesin family member 3C
chr12_-_45270077 35.16 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NEL-like 2 (chicken)
chr5_-_146435572 35.12 ENST00000394414.1
protein phosphatase 2, regulatory subunit B, beta
chr1_+_50571949 35.12 ENST00000357083.4
ELAV like neuron-specific RNA binding protein 4
chr18_-_74844727 34.72 ENST00000355994.2
ENST00000579129.1
myelin basic protein
chr6_-_128841503 34.55 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
protein tyrosine phosphatase, receptor type, K
chr20_+_44036620 33.52 ENST00000372710.3
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr11_-_111794446 31.30 ENST00000527950.1
crystallin, alpha B
chr5_-_16936340 30.67 ENST00000507288.1
ENST00000513610.1
myosin X
chr4_-_5890145 30.56 ENST00000397890.2
collapsin response mediator protein 1
chr4_+_41614909 29.98 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIM and calponin homology domains 1
chr1_+_169075554 29.90 ENST00000367815.4
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr2_+_17721920 29.12 ENST00000295156.4
visinin-like 1
chr12_-_49582978 29.07 ENST00000301071.7
tubulin, alpha 1a
chr3_-_58563094 29.03 ENST00000464064.1
family with sequence similarity 107, member A
chr9_+_103235365 28.94 ENST00000374879.4
transmembrane protein with EGF-like and two follistatin-like domains 1
chr12_-_45307711 28.88 ENST00000333837.4
ENST00000551949.1
NEL-like 2 (chicken)
chr16_+_6069586 28.75 ENST00000547372.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr10_-_97321165 28.39 ENST00000306402.6
sorbin and SH3 domain containing 1
chr1_-_182360498 26.94 ENST00000417584.2
glutamate-ammonia ligase
chr5_+_140749803 26.85 ENST00000576222.1
protocadherin gamma subfamily B, 3
chr12_-_49582593 26.65 ENST00000295766.5
tubulin, alpha 1a
chr5_+_140797296 25.23 ENST00000398594.2
protocadherin gamma subfamily B, 7
chr11_-_111781454 24.89 ENST00000533280.1
crystallin, alpha B
chr11_-_111781610 24.82 ENST00000525823.1
crystallin, alpha B
chr5_-_146833485 24.54 ENST00000398514.3
dihydropyrimidinase-like 3
chr6_+_126240442 24.52 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
nuclear receptor coactivator 7
chr1_-_156217829 24.01 ENST00000356983.2
ENST00000335852.1
ENST00000340183.5
ENST00000540423.1
progestin and adipoQ receptor family member VI
chr1_-_156217822 23.97 ENST00000368270.1
progestin and adipoQ receptor family member VI
chr5_+_140213815 23.73 ENST00000525929.1
ENST00000378125.3
protocadherin alpha 7
chr1_-_32801825 23.65 ENST00000329421.7
MARCKS-like 1
chr2_-_166060552 23.16 ENST00000283254.7
ENST00000453007.1
sodium channel, voltage-gated, type III, alpha subunit
chr11_-_111781554 23.04 ENST00000526167.1
ENST00000528961.1
crystallin, alpha B
chr7_+_73703728 22.94 ENST00000361545.5
ENST00000223398.6
CAP-GLY domain containing linker protein 2
chrX_+_103031758 22.94 ENST00000303958.2
ENST00000361621.2
proteolipid protein 1
chr16_+_6069072 22.85 ENST00000547605.1
ENST00000550418.1
ENST00000553186.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr1_-_95391315 22.72 ENST00000545882.1
ENST00000415017.1
calponin 3, acidic
chr14_+_96505659 22.71 ENST00000555004.1
chromosome 14 open reading frame 132
chr12_-_105478339 22.65 ENST00000424857.2
ENST00000258494.9
aldehyde dehydrogenase 1 family, member L2
chr1_-_156217875 22.46 ENST00000292291.5
progestin and adipoQ receptor family member VI
chrX_+_103031421 22.43 ENST00000433491.1
ENST00000418604.1
ENST00000443502.1
proteolipid protein 1
chr15_+_84115868 22.24 ENST00000427482.2
SH3-domain GRB2-like 3
chr8_-_120685608 22.21 ENST00000427067.2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chrX_-_13835147 21.97 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chr3_-_149688655 21.83 ENST00000461930.1
ENST00000423691.2
ENST00000490975.1
ENST00000461868.1
ENST00000452853.2
profilin 2
chr8_-_17579726 21.71 ENST00000381861.3
microtubule associated tumor suppressor 1
chr17_+_30813576 21.57 ENST00000313401.3
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr6_-_3227877 21.32 ENST00000259818.7
tubulin, beta 2B class IIb
chr2_-_2334888 21.29 ENST00000428368.2
ENST00000399161.2
myelin transcription factor 1-like
chrX_+_38420783 21.05 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
tetraspanin 7
chr9_-_123476719 20.74 ENST00000373930.3
multiple EGF-like-domains 9
chr3_+_159557637 20.43 ENST00000445224.2
schwannomin interacting protein 1
chr12_+_124997766 20.39 ENST00000543970.1
RP11-83B20.1
chr8_-_27468842 20.34 ENST00000523500.1
clusterin
chrX_-_13956737 20.33 ENST00000454189.2
glycoprotein M6B
chr16_+_15528332 20.29 ENST00000566490.1
chromosome 16 open reading frame 45
chr2_-_55276320 20.28 ENST00000357376.3
reticulon 4
chr11_-_76155618 19.80 ENST00000530759.1
RP11-111M22.3
chr21_+_41239243 19.73 ENST00000328619.5
Purkinje cell protein 4
chr14_+_101299520 19.63 ENST00000455531.1
maternally expressed 3 (non-protein coding)
chr2_+_17721230 19.62 ENST00000457525.1
visinin-like 1
chr4_+_154125565 19.52 ENST00000338700.5
tripartite motif containing 2
chr20_-_4804244 19.34 ENST00000379400.3
Ras association (RalGDS/AF-6) domain family member 2
chr8_+_79578282 19.26 ENST00000263849.4
zinc finger, C2HC-type containing 1A
chr15_+_84116106 19.18 ENST00000535412.1
ENST00000324537.5
SH3-domain GRB2-like 3
chr12_-_50294033 18.92 ENST00000552669.1
Fas apoptotic inhibitory molecule 2
chr3_-_149688502 18.80 ENST00000481767.1
ENST00000475518.1
profilin 2
chr9_-_123476612 18.69 ENST00000426959.1
multiple EGF-like-domains 9
chr2_-_166060571 18.51 ENST00000360093.3
sodium channel, voltage-gated, type III, alpha subunit
chr14_-_21493123 18.48 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
NDRG family member 2
chr14_-_21516590 18.47 ENST00000555026.1
NDRG family member 2
chrX_+_16737718 18.10 ENST00000380155.3
synapse associated protein 1
chr2_-_224903995 17.81 ENST00000409304.1
ENST00000454956.1
ENST00000258405.4
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr3_-_149688896 17.81 ENST00000239940.7
profilin 2
chr7_-_22233442 17.56 ENST00000401957.2
Rap guanine nucleotide exchange factor (GEF) 5
chr8_-_27468945 17.48 ENST00000405140.3
clusterin
chr11_-_76155700 17.34 ENST00000572035.1
RP11-111M22.3
chrX_+_51927919 17.34 ENST00000416960.1
melanoma antigen family D, 4
chr19_+_58095501 17.06 ENST00000536878.2
ENST00000597850.1
ENST00000597219.1
ENST00000598689.1
ENST00000599456.1
ENST00000307468.4
zinc finger protein interacting with K protein 1
chr11_+_60691924 17.04 ENST00000544065.1
ENST00000453848.2
ENST00000005286.4
transmembrane protein 132A
chr7_+_29234101 16.98 ENST00000435288.2
chimerin 2
chr4_-_174320687 16.80 ENST00000296506.3
stimulator of chondrogenesis 1
chr12_-_16759711 16.75 ENST00000447609.1
LIM domain only 3 (rhombotin-like 2)
chr15_+_78730622 16.66 ENST00000560440.1
iron-responsive element binding protein 2
chr4_+_41258786 16.55 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr1_-_156399184 16.47 ENST00000368243.1
ENST00000357975.4
ENST00000310027.5
ENST00000400991.2
chromosome 1 open reading frame 61
chr3_+_159570722 16.45 ENST00000482804.1
schwannomin interacting protein 1
chr2_-_9143786 16.43 ENST00000462696.1
ENST00000305997.3
membrane bound O-acyltransferase domain containing 2
chr2_-_86564776 16.42 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
receptor accessory protein 1
chr1_+_200708671 16.39 ENST00000358823.2
calmodulin regulated spectrin-associated protein family, member 2
chr1_+_11751748 16.18 ENST00000294485.5
dorsal inhibitory axon guidance protein
chr6_+_123100620 16.02 ENST00000368444.3
fatty acid binding protein 7, brain
chr20_+_44036900 15.93 ENST00000443296.1
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr10_-_97321112 15.89 ENST00000607232.1
ENST00000371227.4
ENST00000371249.2
ENST00000371247.2
ENST00000371246.2
ENST00000393949.1
ENST00000353505.5
ENST00000347291.4
sorbin and SH3 domain containing 1
chr11_+_125365110 15.76 ENST00000527818.1
AP000708.1
chr1_+_156589051 15.56 ENST00000255039.1
hyaluronan and proteoglycan link protein 2
chr1_+_169079823 15.56 ENST00000367813.3
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr19_-_42498231 15.54 ENST00000602133.1
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr3_-_195310802 15.50 ENST00000421243.1
ENST00000453131.1
apolipoprotein D
chr8_-_27469196 15.45 ENST00000546343.1
ENST00000560566.1
clusterin
chr19_-_42498369 15.35 ENST00000302102.5
ENST00000545399.1
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr1_+_50569575 15.33 ENST00000371827.1
ELAV like neuron-specific RNA binding protein 4
chr1_+_92632542 15.26 ENST00000409154.4
ENST00000370378.4
KIAA1107
chr20_+_11898507 15.20 ENST00000378226.2
BTB (POZ) domain containing 3
chr17_+_43971643 14.96 ENST00000344290.5
ENST00000262410.5
ENST00000351559.5
ENST00000340799.5
ENST00000535772.1
ENST00000347967.5
microtubule-associated protein tau
chr4_-_87281196 14.78 ENST00000359221.3
mitogen-activated protein kinase 10
chr8_+_79428539 14.72 ENST00000352966.5
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr17_+_57232690 14.60 ENST00000262293.4
proline rich 11
chr3_-_167813672 14.60 ENST00000470487.1
golgi integral membrane protein 4
chrX_-_72434628 14.59 ENST00000536638.1
ENST00000373517.3
nucleosome assembly protein 1-like 2
chr18_+_32558208 14.57 ENST00000436190.2
microtubule-associated protein, RP/EB family, member 2
chr7_-_137028498 14.29 ENST00000393083.2
pleiotrophin
chrX_+_100333709 14.08 ENST00000372930.4
transmembrane protein 35
chr6_+_30848557 14.03 ENST00000460944.2
ENST00000324771.8
discoidin domain receptor tyrosine kinase 1
chr1_+_150229554 14.02 ENST00000369111.4
carbonic anhydrase XIV
chr22_+_19701985 14.02 ENST00000455784.2
ENST00000406395.1
septin 5
chr7_-_137028534 13.93 ENST00000348225.2
pleiotrophin
chr1_-_177134024 13.90 ENST00000367654.3
astrotactin 1
chr1_-_9811600 13.90 ENST00000435891.1
calsyntenin 1
chr7_+_95401851 13.87 ENST00000447467.2
dynein, cytoplasmic 1, intermediate chain 1
chr7_+_29234028 13.87 ENST00000222792.6
chimerin 2
chr17_+_43972010 13.78 ENST00000334239.8
ENST00000446361.3
microtubule-associated protein tau
chr4_+_71587669 13.76 ENST00000381006.3
ENST00000226328.4
RUN and FYVE domain containing 3
chr13_-_45150392 13.62 ENST00000501704.2
TSC22 domain family, member 1
chr7_+_95401877 13.44 ENST00000524053.1
ENST00000324972.6
ENST00000537881.1
ENST00000437599.1
ENST00000359388.4
ENST00000413338.1
dynein, cytoplasmic 1, intermediate chain 1
chr1_-_177133818 13.43 ENST00000424564.2
ENST00000361833.2
astrotactin 1
chr10_-_70092635 13.40 ENST00000309049.4
phenazine biosynthesis-like protein domain containing
chr5_+_140729649 13.37 ENST00000523390.1
protocadherin gamma subfamily B, 1
chr8_-_110620284 13.30 ENST00000529690.1
syntabulin (syntaxin-interacting)
chr6_+_114178512 13.27 ENST00000368635.4
myristoylated alanine-rich protein kinase C substrate
chr9_-_91793675 13.22 ENST00000375835.4
ENST00000375830.1
SHC (Src homology 2 domain containing) transforming protein 3
chr11_-_123525289 13.17 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
sodium channel, voltage-gated, type III, beta subunit
chr19_-_6502304 13.05 ENST00000540257.1
ENST00000594276.1
ENST00000594075.1
ENST00000600216.1
ENST00000596926.1
tubulin, beta 4A class IVa
chr17_-_9940058 13.04 ENST00000585266.1
growth arrest-specific 7
chr10_-_99393208 13.01 ENST00000307450.6
MORN repeat containing 4
chr18_+_56530794 12.78 ENST00000590285.1
ENST00000586085.1
ENST00000589288.1
zinc finger protein 532
chr6_-_41863098 12.77 ENST00000373006.1
ubiquitin specific peptidase 49
chr1_-_26232522 12.75 ENST00000399728.1
stathmin 1
chr4_+_154074217 12.71 ENST00000437508.2
tripartite motif containing 2
chr4_+_156680153 12.70 ENST00000502959.1
ENST00000505764.1
ENST00000507146.1
ENST00000264424.8
ENST00000503520.1
guanylate cyclase 1, soluble, beta 3
chr10_+_18429606 12.68 ENST00000324631.7
ENST00000352115.6
ENST00000377328.1
calcium channel, voltage-dependent, beta 2 subunit
chr18_+_21719018 12.63 ENST00000585037.1
ENST00000415309.2
ENST00000399481.2
ENST00000577705.1
ENST00000327201.6
calcium binding tyrosine-(Y)-phosphorylation regulated
chr1_-_230513367 12.63 ENST00000321327.2
ENST00000525115.1
piggyBac transposable element derived 5
chr6_-_46459099 12.55 ENST00000371374.1
regulator of calcineurin 2
chrX_-_51812268 12.48 ENST00000486010.1
ENST00000497164.1
ENST00000360134.6
ENST00000485287.1
ENST00000335504.5
ENST00000431659.1
melanoma antigen family D, 4B
chr4_-_87281224 12.45 ENST00000395169.3
ENST00000395161.2
mitogen-activated protein kinase 10
chr1_-_26232951 12.14 ENST00000426559.2
ENST00000455785.2
stathmin 1
chr18_+_21718924 12.05 ENST00000399496.3
calcium binding tyrosine-(Y)-phosphorylation regulated
chr4_+_41540160 11.95 ENST00000503057.1
ENST00000511496.1
LIM and calponin homology domains 1
chr2_+_210517895 11.93 ENST00000447185.1
microtubule-associated protein 2
chr4_+_106629929 11.82 ENST00000512828.1
ENST00000394730.3
ENST00000507281.1
ENST00000515279.1
glutathione S-transferase, C-terminal domain containing
chr20_+_20348740 11.81 ENST00000310227.1
insulinoma-associated 1
chr2_+_61293021 11.72 ENST00000402291.1
KIAA1841
chr8_-_29940464 11.71 ENST00000521265.1
ENST00000536273.1
transmembrane protein 66
chr7_+_16793160 11.55 ENST00000262067.4
tetraspanin 13
chr19_+_45409011 11.50 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
apolipoprotein E
chr17_-_1083078 11.49 ENST00000574266.1
ENST00000302538.5
active BCR-related
chrX_+_102631844 11.49 ENST00000372634.1
ENST00000299872.7
nerve growth factor receptor (TNFRSF16) associated protein 1
chrX_+_102469997 11.47 ENST00000372695.5
ENST00000372691.3
brain expressed, X-linked 4
chr19_+_50354462 11.26 ENST00000601675.1
prostate tumor overexpressed 1
chr19_+_7580944 11.20 ENST00000597229.1
zinc finger protein 358
chr5_+_140753444 11.06 ENST00000517434.1
protocadherin gamma subfamily A, 6
chr7_+_86273952 11.06 ENST00000536043.1
glutamate receptor, metabotropic 3
chr2_+_242127924 11.03 ENST00000402530.3
ENST00000274979.8
ENST00000402430.3
anoctamin 7
chr12_-_16761007 11.00 ENST00000354662.1
ENST00000441439.2
LIM domain only 3 (rhombotin-like 2)
chr8_+_105235572 10.91 ENST00000523362.1
regulating synaptic membrane exocytosis 2
chr15_-_49338748 10.91 ENST00000559471.1
SECIS binding protein 2-like
chr19_+_50354430 10.88 ENST00000599732.1
prostate tumor overexpressed 1
chr9_-_98079965 10.87 ENST00000289081.3
Fanconi anemia, complementation group C
chr1_+_164528866 10.84 ENST00000420696.2
pre-B-cell leukemia homeobox 1
chr5_+_140743859 10.80 ENST00000518069.1
protocadherin gamma subfamily A, 5
chr7_+_154002189 10.77 ENST00000332007.3
dipeptidyl-peptidase 6
chr18_-_5419797 10.75 ENST00000542146.1
ENST00000427684.2
erythrocyte membrane protein band 4.1-like 3
chr7_+_30960915 10.69 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
aquaporin 1 (Colton blood group)
chr15_-_49338624 10.64 ENST00000261847.3
ENST00000380927.2
ENST00000559424.1
SECIS binding protein 2-like
chr7_-_111846435 10.64 ENST00000437633.1
ENST00000428084.1
dedicator of cytokinesis 4
chr1_-_46598371 10.50 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr17_+_57297807 10.42 ENST00000284116.4
ENST00000581140.1
ENST00000581276.1
glycerophosphodiester phosphodiesterase domain containing 1
chr19_-_37019136 10.36 ENST00000592282.1
zinc finger protein 260

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX3_SOX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
36.3 181.4 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
15.9 63.4 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
12.5 62.6 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
11.8 47.3 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
11.4 113.5 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
10.2 30.6 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
9.4 28.2 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
8.9 53.3 GO:0061517 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
8.3 124.9 GO:0030050 vesicle transport along actin filament(GO:0030050)
8.2 24.5 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
7.6 22.7 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
7.3 36.6 GO:0030382 sperm mitochondrion organization(GO:0030382)
7.2 100.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
6.9 20.7 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
6.4 25.7 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
6.1 18.3 GO:2000830 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
5.9 23.6 GO:0006542 glutamine biosynthetic process(GO:0006542)
5.7 11.5 GO:1901628 positive regulation of postsynaptic membrane organization(GO:1901628)
5.7 28.7 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
5.6 101.0 GO:0007021 tubulin complex assembly(GO:0007021)
5.5 16.6 GO:0007412 axon target recognition(GO:0007412)
5.4 16.3 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
5.1 20.3 GO:1903976 negative regulation of glial cell migration(GO:1903976)
5.1 20.2 GO:0021564 vagus nerve development(GO:0021564)
4.9 58.4 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
4.8 19.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
4.7 109.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
4.6 27.7 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
4.5 22.3 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
4.2 25.3 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
3.9 51.3 GO:2001135 regulation of endocytic recycling(GO:2001135)
3.9 11.8 GO:0003358 noradrenergic neuron development(GO:0003358)
3.9 30.9 GO:0060075 regulation of resting membrane potential(GO:0060075)
3.8 15.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
3.8 15.0 GO:0072658 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
3.8 7.5 GO:1902809 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
3.6 10.7 GO:0072229 carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
3.6 17.8 GO:0061107 seminal vesicle development(GO:0061107)
3.4 10.3 GO:0032900 regulation of nucleoside transport(GO:0032242) negative regulation of neurotrophin production(GO:0032900)
3.4 27.2 GO:0007258 JUN phosphorylation(GO:0007258)
3.3 9.8 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
3.2 45.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
3.2 12.8 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
3.2 63.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
2.9 45.8 GO:2000574 regulation of microtubule motor activity(GO:2000574)
2.8 42.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
2.8 8.4 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
2.8 8.4 GO:0052026 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
2.8 14.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
2.8 8.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
2.6 34.3 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
2.6 5.2 GO:0060260 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) regulation of transcription initiation from RNA polymerase II promoter(GO:0060260)
2.6 10.3 GO:0021888 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
2.5 7.5 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
2.5 7.5 GO:0097114 NMDA glutamate receptor clustering(GO:0097114)
2.5 10.0 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763) regulation of glutamate metabolic process(GO:2000211)
2.4 14.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
2.4 2.4 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
2.4 4.7 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
2.3 37.0 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
2.3 36.7 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
2.3 38.9 GO:0019371 cyclooxygenase pathway(GO:0019371)
2.3 6.8 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
2.2 28.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
2.2 6.5 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
2.2 4.3 GO:0015670 carbon dioxide transport(GO:0015670)
2.1 6.4 GO:0043153 photoperiodism(GO:0009648) entrainment of circadian clock by photoperiod(GO:0043153)
2.1 14.6 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
2.1 22.6 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
2.0 10.2 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
2.0 30.6 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
2.0 16.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
2.0 6.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
1.9 5.8 GO:0010643 cell communication by chemical coupling(GO:0010643)
1.9 17.3 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
1.9 11.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
1.9 16.9 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
1.9 13.2 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
1.9 9.3 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
1.8 38.4 GO:0051764 actin crosslink formation(GO:0051764)
1.8 7.2 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
1.8 25.0 GO:0021516 dorsal spinal cord development(GO:0021516)
1.8 14.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
1.7 7.0 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
1.7 8.7 GO:0031022 nuclear migration along microfilament(GO:0031022)
1.7 8.6 GO:0016476 regulation of embryonic cell shape(GO:0016476)
1.7 5.1 GO:0035607 fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development(GO:0035607)
1.7 1.7 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
1.7 1.7 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
1.6 8.2 GO:0003322 pancreatic A cell development(GO:0003322)
1.6 21.3 GO:1902669 positive regulation of axon guidance(GO:1902669)
1.6 24.0 GO:0021681 cerebellar granular layer development(GO:0021681)
1.6 7.9 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
1.6 45.3 GO:0008045 motor neuron axon guidance(GO:0008045)
1.6 7.8 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
1.5 10.7 GO:0002175 protein localization to paranode region of axon(GO:0002175)
1.5 22.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
1.5 40.8 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
1.4 4.3 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
1.4 5.7 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
1.4 10.0 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
1.4 14.1 GO:0016198 axon choice point recognition(GO:0016198)
1.4 5.5 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
1.4 2.7 GO:0021586 pons maturation(GO:0021586)
1.3 4.0 GO:1990637 response to prolactin(GO:1990637)
1.3 10.7 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
1.3 6.6 GO:0051013 microtubule severing(GO:0051013)
1.3 7.9 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
1.3 6.6 GO:0035900 response to isolation stress(GO:0035900)
1.3 35.4 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
1.3 5.2 GO:0042483 negative regulation of odontogenesis(GO:0042483)
1.3 13.1 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
1.3 11.7 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
1.3 27.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
1.3 23.1 GO:0003351 epithelial cilium movement(GO:0003351)
1.3 5.1 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
1.3 2.5 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
1.3 10.1 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
1.2 3.7 GO:0051036 regulation of endosome size(GO:0051036)
1.2 6.0 GO:0071279 cellular response to cobalt ion(GO:0071279)
1.2 8.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
1.2 7.1 GO:0051012 microtubule sliding(GO:0051012)
1.2 10.6 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
1.2 3.5 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
1.1 3.4 GO:0007538 primary sex determination(GO:0007538)
1.1 7.9 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
1.1 5.6 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
1.1 4.5 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
1.1 8.8 GO:0032790 ribosome disassembly(GO:0032790)
1.1 27.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
1.1 3.3 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
1.1 7.5 GO:1903977 NMDA selective glutamate receptor signaling pathway(GO:0098989) positive regulation of glial cell migration(GO:1903977)
1.1 3.2 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
1.0 40.5 GO:0086010 membrane depolarization during action potential(GO:0086010)
1.0 40.5 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
1.0 3.0 GO:0006059 hexitol metabolic process(GO:0006059) response to methylglyoxal(GO:0051595)
1.0 2.0 GO:1902473 regulation of protein localization to synapse(GO:1902473) positive regulation of protein localization to synapse(GO:1902474)
1.0 18.7 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
1.0 9.7 GO:0006600 creatine metabolic process(GO:0006600)
1.0 15.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.9 2.8 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.9 15.1 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.9 3.7 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.9 7.4 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.9 2.8 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.9 23.7 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.9 5.4 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.9 8.1 GO:0042574 retinal metabolic process(GO:0042574)
0.9 2.7 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.9 7.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.9 2.7 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.9 6.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.9 3.5 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.9 2.6 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.9 4.3 GO:1900736 minus-end-directed organelle transport along microtubule(GO:0072385) regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.9 12.9 GO:0032196 transposition(GO:0032196)
0.9 8.6 GO:0009249 protein lipoylation(GO:0009249)
0.9 5.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.8 4.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.8 6.7 GO:2000790 regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791)
0.8 2.5 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.8 9.8 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.8 10.6 GO:0090527 actin filament reorganization(GO:0090527)
0.8 2.4 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.8 1.6 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394)
0.8 5.6 GO:0009597 detection of virus(GO:0009597)
0.8 9.5 GO:0060134 prepulse inhibition(GO:0060134)
0.8 2.4 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.8 6.2 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.8 9.9 GO:0017121 phospholipid scrambling(GO:0017121)
0.8 1.5 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.8 3.8 GO:0034587 piRNA metabolic process(GO:0034587)
0.8 1.5 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.7 3.0 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.7 3.6 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.7 114.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.7 2.2 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.7 10.0 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.7 1.4 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.7 5.6 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.7 3.5 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.7 8.3 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.7 4.8 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.7 4.8 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.7 29.2 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.7 8.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.7 5.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.7 2.0 GO:1900244 positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423)
0.7 2.0 GO:0032229 negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.6 5.8 GO:0015747 urate transport(GO:0015747)
0.6 14.6 GO:0048665 neuron fate specification(GO:0048665)
0.6 1.3 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.6 1.9 GO:0021781 glial cell fate commitment(GO:0021781)
0.6 5.6 GO:0030091 protein repair(GO:0030091)
0.6 2.5 GO:1902731 negative regulation of chondrocyte proliferation(GO:1902731)
0.6 3.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.6 3.7 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.6 1.2 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.6 23.3 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.6 14.3 GO:0006833 water transport(GO:0006833)
0.6 8.9 GO:0034063 stress granule assembly(GO:0034063)
0.6 28.8 GO:0015701 bicarbonate transport(GO:0015701)
0.6 11.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.6 4.5 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.6 2.2 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.5 1.1 GO:0015791 polyol transport(GO:0015791)
0.5 14.2 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.5 2.0 GO:0018094 protein polyglycylation(GO:0018094)
0.5 3.0 GO:0099624 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914) atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.5 5.4 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.5 1.9 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.5 4.9 GO:0030509 BMP signaling pathway(GO:0030509)
0.5 27.5 GO:0072384 organelle transport along microtubule(GO:0072384)
0.5 1.4 GO:0032252 secretory granule localization(GO:0032252)
0.5 3.8 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.5 1.9 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.5 19.3 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.5 1.9 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.5 3.2 GO:0032760 positive regulation of tumor necrosis factor production(GO:0032760) positive regulation of tumor necrosis factor superfamily cytokine production(GO:1903557)
0.5 1.9 GO:0015705 iodide transport(GO:0015705)
0.5 8.7 GO:0006068 ethanol catabolic process(GO:0006068)
0.5 5.9 GO:0033623 regulation of integrin activation(GO:0033623)
0.4 4.0 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.4 7.6 GO:0002467 germinal center formation(GO:0002467)
0.4 7.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.4 1.3 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.4 3.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.4 6.6 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.4 1.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.4 10.9 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.4 2.2 GO:0061511 centriole elongation(GO:0061511)
0.4 1.7 GO:2000662 interleukin-5 secretion(GO:0072603) regulation of interleukin-5 secretion(GO:2000662)
0.4 0.9 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.4 1.3 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.4 1.3 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.4 5.1 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.4 2.1 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.4 4.6 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.4 4.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.4 1.2 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.4 8.1 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.4 9.2 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.4 1.2 GO:0035425 autocrine signaling(GO:0035425)
0.4 8.7 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.4 31.0 GO:0030010 establishment of cell polarity(GO:0030010)
0.4 5.0 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.4 6.9 GO:0016540 protein autoprocessing(GO:0016540)
0.4 13.0 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.4 1.9 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.4 3.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.4 2.6 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.4 4.8 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.4 1.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.4 4.3 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.4 0.7 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.3 5.9 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.3 1.0 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.3 2.4 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.3 8.5 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.3 6.5 GO:0019228 neuronal action potential(GO:0019228)
0.3 5.8 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.3 6.1 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.3 46.4 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.3 4.0 GO:0060004 reflex(GO:0060004)
0.3 11.5 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.3 1.6 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.3 2.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.3 5.4 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.3 6.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.3 0.3 GO:0014028 notochord formation(GO:0014028)
0.3 1.6 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.3 3.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.3 4.6 GO:0031111 negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.3 1.2 GO:0021626 hindbrain maturation(GO:0021578) central nervous system maturation(GO:0021626)
0.3 0.9 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.3 3.0 GO:0015865 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.3 2.4 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.3 2.7 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.3 7.1 GO:0015695 organic cation transport(GO:0015695)
0.3 3.2 GO:0009303 rRNA transcription(GO:0009303)
0.3 0.3 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.3 1.7 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.3 4.8 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.3 7.3 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.3 1.1 GO:0030259 lipid glycosylation(GO:0030259)
0.3 0.3 GO:0014016 neuroblast differentiation(GO:0014016)
0.3 4.1 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.3 51.1 GO:0007411 axon guidance(GO:0007411)
0.3 1.4 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.3 1.6 GO:0032275 luteinizing hormone secretion(GO:0032275)
0.3 0.8 GO:2000328 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320) regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.3 1.5 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.2 15.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.2 3.2 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.2 17.2 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.2 1.2 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364) vitamin B6 metabolic process(GO:0042816)
0.2 1.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.2 1.2 GO:0032808 lacrimal gland development(GO:0032808)
0.2 2.8 GO:0051382 kinetochore assembly(GO:0051382)
0.2 0.9 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.2 3.7 GO:0034766 negative regulation of ion transmembrane transport(GO:0034766)
0.2 0.6 GO:0034443 regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443)
0.2 4.3 GO:0060292 long term synaptic depression(GO:0060292)
0.2 2.7 GO:2000194 regulation of female gonad development(GO:2000194)
0.2 13.7 GO:0035308 negative regulation of protein dephosphorylation(GO:0035308)
0.2 0.4 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.2 2.0 GO:0010265 SCF complex assembly(GO:0010265)
0.2 3.4 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.2 8.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.2 1.0 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.2 1.6 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.2 4.8 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.2 2.1 GO:1903522 regulation of blood circulation(GO:1903522)
0.2 0.6 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.2 1.5 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 6.3 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.2 0.6 GO:0017158 regulation of calcium ion-dependent exocytosis(GO:0017158)
0.2 10.4 GO:0006826 iron ion transport(GO:0006826)
0.2 5.0 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.2 6.2 GO:0021510 spinal cord development(GO:0021510)
0.2 1.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2 1.4 GO:0000733 DNA strand renaturation(GO:0000733)
0.2 2.7 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.2 3.4 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.2 2.5 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.2 12.3 GO:0021987 cerebral cortex development(GO:0021987)
0.2 0.7 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.2 0.5 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.2 6.3 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.2 6.0 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.2 1.0 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.2 3.6 GO:0006825 copper ion transport(GO:0006825)
0.1 1.8 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 1.9 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 1.5 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.1 1.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.6 GO:0048286 lung alveolus development(GO:0048286)
0.1 1.1 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.1 5.3 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.1 1.0 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 1.9 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 1.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 8.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 0.5 GO:0006408 snRNA export from nucleus(GO:0006408)
0.1 1.1 GO:0090169 regulation of spindle assembly(GO:0090169) regulation of mitotic spindle assembly(GO:1901673)
0.1 1.2 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 4.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 2.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.4 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.6 GO:0035063 nuclear speck organization(GO:0035063)
0.1 1.4 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 2.0 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 2.2 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.1 2.1 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 3.0 GO:0007340 acrosome reaction(GO:0007340)
0.1 0.2 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 0.7 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.6 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.7 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 1.6 GO:0006020 inositol metabolic process(GO:0006020)
0.1 1.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.3 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.1 0.5 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 3.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 0.5 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 1.0 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 0.8 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262) determination of dorsal identity(GO:0048263)
0.1 0.7 GO:0090128 regulation of synapse maturation(GO:0090128)
0.1 2.2 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 0.6 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 1.1 GO:0046320 regulation of fatty acid oxidation(GO:0046320)
0.1 4.1 GO:0000045 autophagosome assembly(GO:0000045)
0.1 0.6 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.1 0.6 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 5.3 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 1.2 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1 0.9 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 3.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 0.1 GO:0042938 dipeptide transport(GO:0042938)
0.1 1.0 GO:0051683 establishment of Golgi localization(GO:0051683)
0.1 1.8 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 4.3 GO:0007041 lysosomal transport(GO:0007041)
0.1 4.1 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 4.2 GO:0007272 ensheathment of neurons(GO:0007272) axon ensheathment(GO:0008366)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.9 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 1.3 GO:0001658 branching involved in ureteric bud morphogenesis(GO:0001658)
0.1 2.0 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.1 5.1 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 0.6 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.1 1.1 GO:0010107 potassium ion import(GO:0010107)
0.1 1.5 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 0.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.8 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 1.6 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.1 0.2 GO:0006004 fucose metabolic process(GO:0006004)
0.0 1.5 GO:0042490 mechanoreceptor differentiation(GO:0042490)
0.0 0.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 2.4 GO:0061337 cardiac conduction(GO:0061337)
0.0 0.6 GO:0030220 platelet formation(GO:0030220)
0.0 0.3 GO:2001054 regulation of mesenchymal cell apoptotic process(GO:2001053) negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.4 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.3 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 1.2 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.7 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.3 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.7 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.6 GO:1904037 positive regulation of epithelial cell apoptotic process(GO:1904037)
0.0 0.6 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.0 1.0 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 1.3 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.0 0.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0046440 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.7 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0 0.3 GO:0001508 action potential(GO:0001508)
0.0 1.0 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.3 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.3 GO:0046135 pyrimidine nucleoside catabolic process(GO:0046135)
0.0 0.0 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 1.1 GO:0061025 membrane fusion(GO:0061025)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.2 GO:0006768 biotin metabolic process(GO:0006768)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
27.3 191.1 GO:0033269 internode region of axon(GO:0033269)
9.2 45.8 GO:0005899 insulin receptor complex(GO:0005899)
6.6 33.0 GO:0045298 tubulin complex(GO:0045298)
6.5 104.0 GO:0097512 cardiac myofibril(GO:0097512)
6.1 24.5 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
5.2 36.3 GO:0044326 dendritic spine neck(GO:0044326)
4.8 14.4 GO:0060053 neurofilament cytoskeleton(GO:0060053)
4.1 53.3 GO:0097418 neurofibrillary tangle(GO:0097418)
4.0 12.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
3.6 21.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
3.6 10.7 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
3.2 45.3 GO:0097227 sperm annulus(GO:0097227)
3.2 54.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
3.1 105.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
3.0 17.8 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
2.9 2.9 GO:0044393 microspike(GO:0044393)
2.9 31.4 GO:0035686 sperm fibrous sheath(GO:0035686)
2.5 33.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
2.5 27.8 GO:0005614 interstitial matrix(GO:0005614)
2.5 45.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
2.2 6.6 GO:0044609 DBIRD complex(GO:0044609)
2.1 42.7 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
1.8 10.9 GO:1990769 proximal neuron projection(GO:1990769)
1.7 26.2 GO:0032433 filopodium tip(GO:0032433)
1.6 8.0 GO:0005594 collagen type IX trimer(GO:0005594)
1.6 3.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
1.6 10.9 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
1.5 29.3 GO:0097386 glial cell projection(GO:0097386)
1.5 55.8 GO:1990752 microtubule end(GO:1990752)
1.5 11.7 GO:0045180 basal cortex(GO:0045180)
1.4 5.7 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
1.4 8.3 GO:0002116 semaphorin receptor complex(GO:0002116)
1.4 5.4 GO:0031417 NatC complex(GO:0031417)
1.3 10.1 GO:0098845 postsynaptic endosome(GO:0098845)
1.3 5.0 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
1.3 15.0 GO:0043194 axon initial segment(GO:0043194)
1.3 12.5 GO:0031045 dense core granule(GO:0031045)
1.2 123.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
1.2 219.5 GO:0030426 growth cone(GO:0030426)
1.1 7.9 GO:0030427 site of polarized growth(GO:0030427)
1.1 89.7 GO:0043195 terminal bouton(GO:0043195)
1.0 31.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
1.0 36.3 GO:0097542 ciliary tip(GO:0097542)
1.0 22.9 GO:0005686 U2 snRNP(GO:0005686)
1.0 5.9 GO:0030893 meiotic cohesin complex(GO:0030893)
1.0 46.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
1.0 10.7 GO:0033270 paranode region of axon(GO:0033270)
0.9 6.6 GO:0005869 dynactin complex(GO:0005869)
0.9 3.7 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.9 6.2 GO:0097427 microtubule bundle(GO:0097427)
0.9 13.3 GO:0043073 germ cell nucleus(GO:0043073)
0.9 17.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.8 10.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.8 126.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.8 20.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.8 8.3 GO:0042587 glycogen granule(GO:0042587)
0.8 5.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.8 16.9 GO:0000812 Swr1 complex(GO:0000812)
0.8 4.8 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.8 3.8 GO:0071546 pi-body(GO:0071546)
0.7 6.0 GO:0043203 axon hillock(GO:0043203)
0.7 2.2 GO:0005960 glycine cleavage complex(GO:0005960)
0.7 36.3 GO:0044306 neuron projection terminus(GO:0044306)
0.7 4.8 GO:0070852 cell body fiber(GO:0070852)
0.7 8.7 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.6 4.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.6 12.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.6 156.6 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.6 3.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.6 38.2 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.6 39.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.6 1.7 GO:0044423 virion(GO:0019012) virion part(GO:0044423)
0.6 2.2 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.5 3.8 GO:1990635 proximal dendrite(GO:1990635)
0.5 1.6 GO:0060187 cell pole(GO:0060187)
0.5 5.8 GO:0044666 MLL3/4 complex(GO:0044666)
0.5 5.1 GO:0060076 excitatory synapse(GO:0060076)
0.5 2.5 GO:0030061 mitochondrial crista(GO:0030061)
0.5 14.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.5 10.6 GO:0042629 mast cell granule(GO:0042629)
0.5 12.9 GO:0048786 presynaptic active zone(GO:0048786)
0.5 19.7 GO:0030315 T-tubule(GO:0030315)
0.4 33.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.4 13.3 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.4 82.6 GO:0005802 trans-Golgi network(GO:0005802)
0.3 13.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.3 4.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.3 4.5 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.3 5.1 GO:0016580 Sin3 complex(GO:0016580)
0.3 4.9 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.3 32.0 GO:0005604 basement membrane(GO:0005604)
0.3 2.5 GO:0000125 PCAF complex(GO:0000125)
0.3 1.9 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 3.1 GO:0030897 HOPS complex(GO:0030897)
0.3 33.2 GO:0030496 midbody(GO:0030496)
0.3 23.1 GO:0005811 lipid particle(GO:0005811)
0.3 7.1 GO:0035869 ciliary transition zone(GO:0035869)
0.3 89.2 GO:0005874 microtubule(GO:0005874)
0.3 16.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.3 4.0 GO:0005662 DNA replication factor A complex(GO:0005662)
0.3 2.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.3 29.3 GO:0031901 early endosome membrane(GO:0031901)
0.3 1.4 GO:0060091 kinocilium(GO:0060091)
0.3 2.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.3 11.4 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.2 0.7 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.2 4.3 GO:0005922 connexon complex(GO:0005922)
0.2 0.7 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.2 3.7 GO:0030673 axolemma(GO:0030673)
0.2 6.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 11.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.2 1.3 GO:0005921 gap junction(GO:0005921)
0.2 12.3 GO:0043204 perikaryon(GO:0043204)
0.2 15.8 GO:0032432 actin filament bundle(GO:0032432)
0.2 3.1 GO:0005875 microtubule associated complex(GO:0005875)
0.2 1.0 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.2 1.9 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 3.1 GO:0032420 stereocilium(GO:0032420)
0.2 45.3 GO:0098857 membrane microdomain(GO:0098857)
0.2 4.8 GO:0030118 clathrin coat(GO:0030118)
0.2 1.3 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.2 21.3 GO:0043209 myelin sheath(GO:0043209)
0.2 0.9 GO:0016589 NURF complex(GO:0016589)
0.2 10.0 GO:0036477 somatodendritic compartment(GO:0036477)
0.2 21.3 GO:0030424 axon(GO:0030424)
0.2 40.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.2 6.0 GO:0016324 apical plasma membrane(GO:0016324)
0.2 1.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.2 15.9 GO:0030139 endocytic vesicle(GO:0030139)
0.2 43.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2 1.8 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.1 GO:0097486 multivesicular body lumen(GO:0097486)
0.1 0.8 GO:0008537 proteasome activator complex(GO:0008537)
0.1 2.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 3.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.9 GO:0099738 cell cortex region(GO:0099738)
0.1 1.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 5.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.1 GO:0045177 apical part of cell(GO:0045177)
0.1 0.7 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 4.5 GO:0031514 motile cilium(GO:0031514)
0.1 5.2 GO:0034702 ion channel complex(GO:0034702)
0.1 6.8 GO:0005938 cell cortex(GO:0005938)
0.1 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 0.9 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 5.7 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 1.9 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 2.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 111.0 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 6.9 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 4.2 GO:0000922 spindle pole(GO:0000922)
0.0 0.5 GO:0030008 TRAPP complex(GO:0030008)
0.0 3.7 GO:0043202 lysosomal lumen(GO:0043202)
0.0 8.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 5.8 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 5.5 GO:0043005 neuron projection(GO:0043005)
0.0 9.6 GO:0044429 mitochondrial part(GO:0044429)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
28.6 343.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
13.9 41.7 GO:0004157 dihydropyrimidinase activity(GO:0004157)
11.5 46.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
8.2 24.5 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
7.6 22.7 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
7.3 58.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
7.2 28.7 GO:0099609 microtubule lateral binding(GO:0099609)
6.2 31.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
6.1 18.3 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
6.0 18.1 GO:0030350 iron-responsive element binding(GO:0030350)
5.9 23.6 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
5.6 22.2 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
4.8 76.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
4.5 27.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
4.1 16.6 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
3.9 54.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
3.8 18.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
3.6 21.5 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
3.6 10.7 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
3.3 29.8 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
3.3 6.6 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
3.2 25.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
3.1 9.4 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
2.9 90.1 GO:0005212 structural constituent of eye lens(GO:0005212)
2.8 14.0 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
2.8 8.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
2.8 13.9 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
2.6 13.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
2.6 52.5 GO:0051787 misfolded protein binding(GO:0051787)
2.5 7.6 GO:0070052 collagen V binding(GO:0070052)
2.5 7.5 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
2.3 23.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
2.3 40.5 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
2.1 36.4 GO:0031005 filamin binding(GO:0031005)
2.1 6.3 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
2.1 12.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
2.1 10.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
2.0 10.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
2.0 90.2 GO:0030507 spectrin binding(GO:0030507)
1.9 9.7 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
1.9 5.7 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
1.9 20.8 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
1.8 7.2 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
1.8 7.1 GO:0005502 11-cis retinal binding(GO:0005502)
1.8 8.8 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
1.7 43.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
1.6 43.7 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
1.6 6.3 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
1.6 4.7 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
1.5 4.5 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
1.5 25.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
1.4 52.2 GO:0017091 AU-rich element binding(GO:0017091)
1.4 6.9 GO:0070097 delta-catenin binding(GO:0070097)
1.4 17.8 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
1.4 8.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
1.4 5.4 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
1.3 3.9 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
1.3 28.8 GO:0002162 dystroglycan binding(GO:0002162)
1.2 3.6 GO:0048763 calcium-induced calcium release activity(GO:0048763)
1.2 9.3 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
1.2 23.3 GO:0051010 microtubule plus-end binding(GO:0051010)
1.1 3.4 GO:0005137 interleukin-5 receptor binding(GO:0005137)
1.1 8.0 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
1.1 134.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
1.1 16.9 GO:0004887 thyroid hormone receptor activity(GO:0004887)
1.1 10.1 GO:0032051 clathrin light chain binding(GO:0032051)
1.1 8.9 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
1.1 29.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
1.1 6.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
1.1 3.3 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
1.1 4.3 GO:0031871 proteinase activated receptor binding(GO:0031871)
1.1 3.2 GO:0008431 vitamin E binding(GO:0008431)
1.0 106.2 GO:0019888 protein phosphatase regulator activity(GO:0019888)
1.0 14.3 GO:0015250 water channel activity(GO:0015250)
1.0 7.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.0 6.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
1.0 4.0 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
1.0 3.0 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
1.0 11.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
1.0 6.0 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
1.0 5.8 GO:0003998 acylphosphatase activity(GO:0003998)
1.0 1.0 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.9 3.7 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.9 23.3 GO:0005521 lamin binding(GO:0005521)
0.9 20.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.9 17.9 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.9 4.5 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.9 21.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.9 5.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.8 4.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.8 11.0 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.8 57.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.8 20.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.8 9.1 GO:0016918 retinal binding(GO:0016918)
0.8 2.4 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.8 10.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.8 8.7 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.8 7.7 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.8 25.7 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.7 3.0 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.7 9.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.7 2.8 GO:0017089 glycolipid transporter activity(GO:0017089) ceramide binding(GO:0097001)
0.7 8.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.7 31.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.7 10.9 GO:0045499 chemorepellent activity(GO:0045499)
0.7 2.6 GO:0004803 transposase activity(GO:0004803)
0.7 2.0 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.6 9.7 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.6 183.7 GO:0015631 tubulin binding(GO:0015631)
0.6 30.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.6 81.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.6 4.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.6 1.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.6 4.0 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.6 3.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.6 14.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.6 2.2 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.5 72.7 GO:0005496 steroid binding(GO:0005496)
0.5 2.7 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.5 2.6 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.5 6.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.5 4.6 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.5 3.6 GO:0035591 signaling adaptor activity(GO:0035591)
0.5 4.5 GO:0051425 PTB domain binding(GO:0051425)
0.5 10.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.5 1.9 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.5 2.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.4 10.0 GO:0031489 myosin V binding(GO:0031489)
0.4 10.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.4 11.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.4 5.1 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.4 3.0 GO:0050733 RS domain binding(GO:0050733)
0.4 7.9 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.4 0.4 GO:0034056 estrogen response element binding(GO:0034056)
0.4 1.2 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.4 10.0 GO:0005523 tropomyosin binding(GO:0005523)
0.4 2.0 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.4 2.8 GO:0030506 ankyrin binding(GO:0030506)
0.4 3.6 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.4 5.1 GO:0038132 neuregulin binding(GO:0038132)
0.4 2.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.4 299.8 GO:0005509 calcium ion binding(GO:0005509)
0.4 1.9 GO:0048039 ubiquinone binding(GO:0048039)
0.4 7.3 GO:0016805 dipeptidase activity(GO:0016805)
0.4 1.5 GO:0019211 phosphatase activator activity(GO:0019211)
0.4 5.6 GO:0005243 gap junction channel activity(GO:0005243)
0.4 14.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.4 2.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.4 1.8 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.4 6.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.3 15.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.3 9.4 GO:0019865 immunoglobulin binding(GO:0019865)
0.3 1.6 GO:0052724 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.3 2.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.3 4.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.3 11.3 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.3 6.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.3 0.9 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.3 1.5 GO:0046923 ER retention sequence binding(GO:0046923)
0.3 0.6 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.3 4.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.3 0.9 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.3 3.9 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.3 8.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.3 1.1 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.3 2.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.3 1.6 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.3 5.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.3 56.5 GO:0000287 magnesium ion binding(GO:0000287)
0.3 3.0 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 9.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.2 2.2 GO:0020037 heme binding(GO:0020037)
0.2 1.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.2 2.8 GO:0031386 protein tag(GO:0031386)
0.2 1.1 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.2 1.5 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 1.7 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.2 3.5 GO:0017136 NAD-dependent histone deacetylase activity(GO:0017136)
0.2 0.8 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.2 1.2 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.2 1.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.2 1.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 6.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2 1.4 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.2 1.0 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.2 2.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 5.3 GO:0005080 protein kinase C binding(GO:0005080)
0.2 1.3 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.2 2.8 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.2 2.0 GO:0097016 L27 domain binding(GO:0097016)
0.2 1.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.2 4.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 1.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.2 24.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.2 3.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 8.7 GO:0001618 virus receptor activity(GO:0001618)
0.2 3.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 1.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2 1.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.2 5.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.2 1.9 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 16.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 11.6 GO:0030165 PDZ domain binding(GO:0030165)
0.2 1.0 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.2 0.6 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.2 1.4 GO:0036310 annealing helicase activity(GO:0036310)
0.2 0.6 GO:0004530 ribonuclease III activity(GO:0004525) deoxyribonuclease I activity(GO:0004530) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.2 0.8 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.2 3.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.6 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 0.7 GO:0005113 patched binding(GO:0005113)
0.1 3.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 1.9 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 2.2 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.5 GO:0015643 toxic substance binding(GO:0015643)
0.1 3.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 16.1 GO:0008201 heparin binding(GO:0008201)
0.1 0.5 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 52.4 GO:0008289 lipid binding(GO:0008289)
0.1 1.8 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.1 0.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.9 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.7 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 1.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 5.0 GO:0002020 protease binding(GO:0002020)
0.1 1.9 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 1.7 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 8.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 2.8 GO:0005109 frizzled binding(GO:0005109)
0.1 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 1.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.8 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 0.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.7 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.3 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.1 4.1 GO:0051117 ATPase binding(GO:0051117)
0.1 3.9 GO:0044325 ion channel binding(GO:0044325)
0.1 1.8 GO:0019894 kinesin binding(GO:0019894)
0.1 2.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.2 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.3 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.1 0.3 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.7 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 1.0 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.3 GO:0031681 thrombin receptor activity(GO:0015057) G-protein beta-subunit binding(GO:0031681)
0.0 2.0 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 12.9 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 4.5 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.5 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.3 GO:0030553 cGMP binding(GO:0030553)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.8 GO:0035064 methylated histone binding(GO:0035064)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 93.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
3.8 7.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
2.7 8.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
1.3 89.7 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
1.2 37.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
1.1 70.6 PID ATR PATHWAY ATR signaling pathway
1.0 71.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.8 1.6 PID S1P S1P2 PATHWAY S1P2 pathway
0.7 42.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.6 5.5 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.6 20.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.6 32.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.6 31.7 PID FAS PATHWAY FAS (CD95) signaling pathway
0.6 31.7 PID INSULIN PATHWAY Insulin Pathway
0.5 11.7 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.4 28.7 PID FGF PATHWAY FGF signaling pathway
0.4 24.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.4 11.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.4 13.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.4 26.1 PID LKB1 PATHWAY LKB1 signaling events
0.3 41.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.3 11.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.3 9.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.3 25.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.3 62.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.3 8.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.3 17.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.2 3.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.2 8.8 PID CDC42 PATHWAY CDC42 signaling events
0.2 10.8 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.2 5.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.2 9.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.2 4.5 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.2 6.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.2 4.8 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.2 6.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 2.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 5.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 2.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 1.7 PID ARF 3PATHWAY Arf1 pathway
0.1 3.1 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 2.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.2 PID IL23 PATHWAY IL23-mediated signaling events
0.1 0.3 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 3.2 PID BMP PATHWAY BMP receptor signaling
0.1 2.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 1.9 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 10.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID SHP2 PATHWAY SHP2 signaling
0.0 0.7 PID ATM PATHWAY ATM pathway
0.0 0.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 138.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
4.3 117.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
1.8 32.8 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
1.8 25.0 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
1.7 91.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
1.7 25.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
1.5 93.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
1.3 5.1 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
1.3 41.9 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
1.2 27.2 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
1.2 18.3 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
1.2 13.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
1.1 8.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
1.1 36.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
1.0 28.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
1.0 23.7 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.9 18.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.8 43.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.6 11.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.6 19.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.5 14.2 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.5 28.7 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.5 6.8 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.5 3.5 REACTOME SIGNALING BY FGFR IN DISEASE Genes involved in Signaling by FGFR in disease
0.5 10.9 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.5 34.6 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.5 11.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.5 5.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.5 8.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.4 4.8 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.4 9.7 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.4 6.7 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.4 7.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.4 43.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.4 6.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.4 1.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.3 7.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.3 10.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.3 8.0 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.3 5.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.3 1.4 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.3 3.8 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.3 9.7 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.3 33.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 1.4 REACTOME G PROTEIN BETA GAMMA SIGNALLING Genes involved in G-protein beta:gamma signalling
0.2 4.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 4.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 3.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.2 4.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 6.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 6.6 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.2 1.3 REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.2 1.0 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.2 10.6 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.2 7.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.2 5.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 3.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.2 6.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 2.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.0 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 2.8 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 3.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 2.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 5.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 3.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 0.7 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 1.7 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 9.1 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 4.2 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 7.0 REACTOME PI3K CASCADE Genes involved in PI3K Cascade
0.1 4.4 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 1.5 REACTOME CD28 CO STIMULATION Genes involved in CD28 co-stimulation
0.1 2.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 0.6 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 0.9 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.0 REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.1 3.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 0.4 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.1 0.7 REACTOME OPSINS Genes involved in Opsins
0.1 2.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.0 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 5.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.5 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 1.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 1.0 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.7 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.1 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 1.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.2 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 2.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.7 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.9 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.2 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 0.1 REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.0 0.6 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 4.0 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation