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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for SOX4
Z-value: 0.80
Motif logo
Transcription factors associated with SOX4
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
SOX4
|
ENSG00000124766.4 | SRY-box transcription factor 4 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SOX4 | hg19_v2_chr6_+_21593972_21594071 | -0.01 | 8.6e-01 | Click! |
Activity profile of SOX4 motif
Sorted Z-values of SOX4 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr14_+_75746781 | 16.84 |
ENST00000555347.1
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog |
| chr1_+_244998602 | 16.62 |
ENST00000411948.2
|
COX20
|
COX20 cytochrome C oxidase assembly factor |
| chr15_-_45670924 | 12.05 |
ENST00000396659.3
|
GATM
|
glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| chr9_+_124088860 | 11.17 |
ENST00000373806.1
|
GSN
|
gelsolin |
| chr15_+_78730622 | 11.09 |
ENST00000560440.1
|
IREB2
|
iron-responsive element binding protein 2 |
| chr20_-_35492048 | 10.76 |
ENST00000237536.4
|
SOGA1
|
suppressor of glucose, autophagy associated 1 |
| chr6_+_41040678 | 10.37 |
ENST00000341376.6
ENST00000353205.5 |
NFYA
|
nuclear transcription factor Y, alpha |
| chr19_+_58095501 | 9.58 |
ENST00000536878.2
ENST00000597850.1 ENST00000597219.1 ENST00000598689.1 ENST00000599456.1 ENST00000307468.4 |
ZIK1
|
zinc finger protein interacting with K protein 1 |
| chr14_-_21516590 | 8.70 |
ENST00000555026.1
|
NDRG2
|
NDRG family member 2 |
| chr10_-_99393208 | 8.53 |
ENST00000307450.6
|
MORN4
|
MORN repeat containing 4 |
| chr13_-_110959478 | 8.24 |
ENST00000543140.1
ENST00000375820.4 |
COL4A1
|
collagen, type IV, alpha 1 |
| chr8_+_80523962 | 8.21 |
ENST00000518491.1
|
STMN2
|
stathmin-like 2 |
| chr20_-_39317868 | 7.97 |
ENST00000373313.2
|
MAFB
|
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| chr5_-_39425290 | 7.71 |
ENST00000545653.1
|
DAB2
|
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| chr14_-_60097297 | 7.51 |
ENST00000395090.1
|
RTN1
|
reticulon 1 |
| chr18_-_74728998 | 7.49 |
ENST00000359645.3
ENST00000397875.3 ENST00000397869.3 ENST00000578193.1 ENST00000578873.1 ENST00000397866.4 ENST00000528160.1 ENST00000527041.1 ENST00000526111.1 ENST00000397865.5 ENST00000382582.3 |
MBP
|
myelin basic protein |
| chr15_+_25200074 | 7.09 |
ENST00000390687.4
ENST00000584968.1 ENST00000346403.6 ENST00000554227.2 |
SNRPN
|
small nuclear ribonucleoprotein polypeptide N |
| chr3_+_39509163 | 7.08 |
ENST00000436143.2
ENST00000441980.2 ENST00000311042.6 |
MOBP
|
myelin-associated oligodendrocyte basic protein |
| chr5_-_39425222 | 7.00 |
ENST00000320816.6
|
DAB2
|
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| chr15_+_78730531 | 6.81 |
ENST00000258886.8
|
IREB2
|
iron-responsive element binding protein 2 |
| chr17_+_80416482 | 6.70 |
ENST00000309794.11
ENST00000345415.7 ENST00000457415.3 ENST00000584411.1 ENST00000412079.2 ENST00000577432.1 |
NARF
|
nuclear prelamin A recognition factor |
| chr7_+_99699280 | 6.64 |
ENST00000421755.1
|
AP4M1
|
adaptor-related protein complex 4, mu 1 subunit |
| chr9_+_101705893 | 6.55 |
ENST00000375001.3
|
COL15A1
|
collagen, type XV, alpha 1 |
| chr12_-_10251576 | 6.44 |
ENST00000315330.4
|
CLEC1A
|
C-type lectin domain family 1, member A |
| chrX_+_12993202 | 6.26 |
ENST00000451311.2
ENST00000380636.1 |
TMSB4X
|
thymosin beta 4, X-linked |
| chr3_+_39509070 | 6.16 |
ENST00000354668.4
ENST00000428261.1 ENST00000420739.1 ENST00000415443.1 ENST00000447324.1 ENST00000383754.3 |
MOBP
|
myelin-associated oligodendrocyte basic protein |
| chr7_+_99699179 | 6.08 |
ENST00000438383.1
ENST00000429084.1 ENST00000359593.4 ENST00000439416.1 |
AP4M1
|
adaptor-related protein complex 4, mu 1 subunit |
| chr4_+_106629929 | 5.88 |
ENST00000512828.1
ENST00000394730.3 ENST00000507281.1 ENST00000515279.1 |
GSTCD
|
glutathione S-transferase, C-terminal domain containing |
| chr12_-_10251603 | 5.87 |
ENST00000457018.2
|
CLEC1A
|
C-type lectin domain family 1, member A |
| chr15_+_25200108 | 5.87 |
ENST00000577949.1
ENST00000338094.6 ENST00000338327.4 ENST00000579070.1 ENST00000577565.1 |
SNURF
SNRPN
|
SNRPN upstream reading frame protein small nuclear ribonucleoprotein polypeptide N |
| chr5_-_39425068 | 5.83 |
ENST00000515700.1
ENST00000339788.6 |
DAB2
|
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| chr5_-_141338627 | 5.46 |
ENST00000231484.3
|
PCDH12
|
protocadherin 12 |
| chr20_-_4804244 | 5.34 |
ENST00000379400.3
|
RASSF2
|
Ras association (RalGDS/AF-6) domain family member 2 |
| chr16_-_68482440 | 5.32 |
ENST00000219334.5
|
SMPD3
|
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) |
| chr13_-_28674693 | 5.24 |
ENST00000537084.1
ENST00000241453.7 ENST00000380982.4 |
FLT3
|
fms-related tyrosine kinase 3 |
| chr22_-_50524298 | 5.16 |
ENST00000311597.5
|
MLC1
|
megalencephalic leukoencephalopathy with subcortical cysts 1 |
| chr17_+_57297807 | 5.01 |
ENST00000284116.4
ENST00000581140.1 ENST00000581276.1 |
GDPD1
|
glycerophosphodiester phosphodiesterase domain containing 1 |
| chr1_-_203151933 | 4.83 |
ENST00000404436.2
|
CHI3L1
|
chitinase 3-like 1 (cartilage glycoprotein-39) |
| chr7_+_139528952 | 4.65 |
ENST00000416849.2
ENST00000436047.2 ENST00000414508.2 ENST00000448866.1 |
TBXAS1
|
thromboxane A synthase 1 (platelet) |
| chr19_-_55690758 | 4.60 |
ENST00000590851.1
|
SYT5
|
synaptotagmin V |
| chr12_-_122296755 | 4.48 |
ENST00000289004.4
|
HPD
|
4-hydroxyphenylpyruvate dioxygenase |
| chr4_-_186877502 | 4.47 |
ENST00000431902.1
ENST00000284776.7 ENST00000415274.1 |
SORBS2
|
sorbin and SH3 domain containing 2 |
| chr2_-_1748214 | 4.38 |
ENST00000433670.1
ENST00000425171.1 ENST00000252804.4 |
PXDN
|
peroxidasin homolog (Drosophila) |
| chr10_+_102222798 | 4.29 |
ENST00000343737.5
|
WNT8B
|
wingless-type MMTV integration site family, member 8B |
| chr19_-_38720294 | 4.29 |
ENST00000412732.1
ENST00000456296.1 |
DPF1
|
D4, zinc and double PHD fingers family 1 |
| chr17_+_25621102 | 4.20 |
ENST00000581440.1
ENST00000262394.2 ENST00000583742.1 ENST00000579733.1 ENST00000583193.1 ENST00000581185.1 ENST00000427287.2 ENST00000348811.2 |
WSB1
|
WD repeat and SOCS box containing 1 |
| chr4_+_71263599 | 4.17 |
ENST00000399575.2
|
PROL1
|
proline rich, lacrimal 1 |
| chr6_+_139456226 | 4.14 |
ENST00000367658.2
|
HECA
|
headcase homolog (Drosophila) |
| chr6_+_72596604 | 4.09 |
ENST00000348717.5
ENST00000517960.1 ENST00000518273.1 ENST00000522291.1 ENST00000521978.1 ENST00000520567.1 ENST00000264839.7 |
RIMS1
|
regulating synaptic membrane exocytosis 1 |
| chr4_+_2819883 | 4.06 |
ENST00000511747.1
ENST00000503393.2 |
SH3BP2
|
SH3-domain binding protein 2 |
| chr12_-_10282836 | 4.06 |
ENST00000304084.8
ENST00000353231.5 ENST00000525605.1 |
CLEC7A
|
C-type lectin domain family 7, member A |
| chr17_+_80416050 | 4.03 |
ENST00000579198.1
ENST00000390006.4 ENST00000580296.1 |
NARF
|
nuclear prelamin A recognition factor |
| chr21_-_33104367 | 3.95 |
ENST00000286835.7
ENST00000399804.1 |
SCAF4
|
SR-related CTD-associated factor 4 |
| chr4_+_78078304 | 3.83 |
ENST00000316355.5
ENST00000354403.5 ENST00000502280.1 |
CCNG2
|
cyclin G2 |
| chr11_-_6677018 | 3.81 |
ENST00000299441.3
|
DCHS1
|
dachsous cadherin-related 1 |
| chr2_-_9143786 | 3.80 |
ENST00000462696.1
ENST00000305997.3 |
MBOAT2
|
membrane bound O-acyltransferase domain containing 2 |
| chr2_-_127977654 | 3.79 |
ENST00000409327.1
|
CYP27C1
|
cytochrome P450, family 27, subfamily C, polypeptide 1 |
| chr6_+_126240442 | 3.70 |
ENST00000448104.1
ENST00000438495.1 ENST00000444128.1 |
NCOA7
|
nuclear receptor coactivator 7 |
| chr16_+_6069586 | 3.65 |
ENST00000547372.1
|
RBFOX1
|
RNA binding protein, fox-1 homolog (C. elegans) 1 |
| chr12_-_95611149 | 3.64 |
ENST00000549499.1
ENST00000343958.4 ENST00000546711.1 |
FGD6
|
FYVE, RhoGEF and PH domain containing 6 |
| chr8_+_79578282 | 3.61 |
ENST00000263849.4
|
ZC2HC1A
|
zinc finger, C2HC-type containing 1A |
| chr5_+_140235469 | 3.60 |
ENST00000506939.2
ENST00000307360.5 |
PCDHA10
|
protocadherin alpha 10 |
| chr10_+_11207438 | 3.56 |
ENST00000609692.1
ENST00000354897.3 |
CELF2
|
CUGBP, Elav-like family member 2 |
| chr5_+_140749803 | 3.55 |
ENST00000576222.1
|
PCDHGB3
|
protocadherin gamma subfamily B, 3 |
| chr10_+_70480963 | 3.54 |
ENST00000265872.6
ENST00000535016.1 ENST00000538031.1 ENST00000543719.1 ENST00000539539.1 ENST00000543225.1 ENST00000536012.1 ENST00000494903.2 |
CCAR1
|
cell division cycle and apoptosis regulator 1 |
| chr8_+_9911778 | 3.48 |
ENST00000317173.4
ENST00000441698.2 |
MSRA
|
methionine sulfoxide reductase A |
| chr7_-_38305279 | 3.42 |
ENST00000443402.2
|
TRGC1
|
T cell receptor gamma constant 1 |
| chr4_+_118955500 | 3.35 |
ENST00000296499.5
|
NDST3
|
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 |
| chr18_+_56530794 | 3.33 |
ENST00000590285.1
ENST00000586085.1 ENST00000589288.1 |
ZNF532
|
zinc finger protein 532 |
| chr19_+_9296279 | 3.22 |
ENST00000344248.2
|
OR7D2
|
olfactory receptor, family 7, subfamily D, member 2 |
| chr19_-_18717627 | 3.22 |
ENST00000392386.3
|
CRLF1
|
cytokine receptor-like factor 1 |
| chrX_+_12993336 | 3.18 |
ENST00000380635.1
|
TMSB4X
|
thymosin beta 4, X-linked |
| chrX_+_65384182 | 3.08 |
ENST00000441993.2
ENST00000419594.1 |
HEPH
|
hephaestin |
| chr5_+_140739537 | 3.03 |
ENST00000522605.1
|
PCDHGB2
|
protocadherin gamma subfamily B, 2 |
| chr7_+_29234101 | 3.00 |
ENST00000435288.2
|
CHN2
|
chimerin 2 |
| chr6_-_133055815 | 2.97 |
ENST00000509351.1
ENST00000417437.2 ENST00000414302.2 ENST00000423615.2 ENST00000427187.2 ENST00000275223.3 ENST00000519686.2 |
VNN3
|
vanin 3 |
| chr1_+_147374915 | 2.87 |
ENST00000240986.4
|
GJA8
|
gap junction protein, alpha 8, 50kDa |
| chr1_-_167883327 | 2.86 |
ENST00000476818.2
ENST00000367851.4 ENST00000367848.1 |
ADCY10
|
adenylate cyclase 10 (soluble) |
| chr1_-_167883353 | 2.83 |
ENST00000545172.1
|
ADCY10
|
adenylate cyclase 10 (soluble) |
| chr5_-_146435694 | 2.82 |
ENST00000356826.3
|
PPP2R2B
|
protein phosphatase 2, regulatory subunit B, beta |
| chrX_+_65384052 | 2.80 |
ENST00000336279.5
ENST00000458621.1 |
HEPH
|
hephaestin |
| chr9_-_104198042 | 2.77 |
ENST00000374855.4
|
ALDOB
|
aldolase B, fructose-bisphosphate |
| chr6_+_43265992 | 2.72 |
ENST00000449231.1
ENST00000372589.3 ENST00000372585.5 |
SLC22A7
|
solute carrier family 22 (organic anion transporter), member 7 |
| chr12_+_93963590 | 2.66 |
ENST00000340600.2
|
SOCS2
|
suppressor of cytokine signaling 2 |
| chr3_-_197024394 | 2.66 |
ENST00000434148.1
ENST00000412364.2 ENST00000436682.1 ENST00000456699.2 ENST00000392380.2 |
DLG1
|
discs, large homolog 1 (Drosophila) |
| chr1_-_243418621 | 2.63 |
ENST00000366544.1
ENST00000366543.1 |
CEP170
|
centrosomal protein 170kDa |
| chr19_+_3880581 | 2.62 |
ENST00000450849.2
ENST00000301260.6 ENST00000398448.3 |
ATCAY
|
ataxia, cerebellar, Cayman type |
| chr5_+_140767452 | 2.62 |
ENST00000519479.1
|
PCDHGB4
|
protocadherin gamma subfamily B, 4 |
| chr3_-_50649192 | 2.60 |
ENST00000443053.2
ENST00000348721.3 |
CISH
|
cytokine inducible SH2-containing protein |
| chr14_+_69658194 | 2.58 |
ENST00000409018.3
ENST00000409014.1 ENST00000409675.1 |
EXD2
|
exonuclease 3'-5' domain containing 2 |
| chr5_-_41213607 | 2.57 |
ENST00000337836.5
ENST00000433294.1 |
C6
|
complement component 6 |
| chr7_-_42276612 | 2.55 |
ENST00000395925.3
ENST00000437480.1 |
GLI3
|
GLI family zinc finger 3 |
| chr14_+_101299520 | 2.53 |
ENST00000455531.1
|
MEG3
|
maternally expressed 3 (non-protein coding) |
| chr17_+_26698677 | 2.50 |
ENST00000457710.3
|
SARM1
|
sterile alpha and TIR motif containing 1 |
| chr5_+_67586465 | 2.48 |
ENST00000336483.5
|
PIK3R1
|
phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| chr10_-_99052382 | 2.45 |
ENST00000453547.2
ENST00000316676.8 ENST00000358308.3 ENST00000466484.1 ENST00000358531.4 |
ARHGAP19-SLIT1
ARHGAP19
|
ARHGAP19-SLIT1 readthrough (NMD candidate) Rho GTPase activating protein 19 |
| chrX_-_73512411 | 2.37 |
ENST00000602576.1
ENST00000429124.1 |
FTX
|
FTX transcript, XIST regulator (non-protein coding) |
| chr16_+_6069072 | 2.37 |
ENST00000547605.1
ENST00000550418.1 ENST00000553186.1 |
RBFOX1
|
RNA binding protein, fox-1 homolog (C. elegans) 1 |
| chrX_+_51927919 | 2.35 |
ENST00000416960.1
|
MAGED4
|
melanoma antigen family D, 4 |
| chr2_-_100721923 | 2.31 |
ENST00000356421.2
|
AFF3
|
AF4/FMR2 family, member 3 |
| chr17_+_64961026 | 2.28 |
ENST00000262138.3
|
CACNG4
|
calcium channel, voltage-dependent, gamma subunit 4 |
| chr2_+_33172221 | 2.27 |
ENST00000354476.3
|
LTBP1
|
latent transforming growth factor beta binding protein 1 |
| chr13_+_111855414 | 2.23 |
ENST00000375737.5
|
ARHGEF7
|
Rho guanine nucleotide exchange factor (GEF) 7 |
| chr14_-_71276211 | 2.23 |
ENST00000381250.4
ENST00000555993.2 |
MAP3K9
|
mitogen-activated protein kinase kinase kinase 9 |
| chr5_-_146435501 | 2.22 |
ENST00000336640.6
|
PPP2R2B
|
protein phosphatase 2, regulatory subunit B, beta |
| chr5_-_146435572 | 2.21 |
ENST00000394414.1
|
PPP2R2B
|
protein phosphatase 2, regulatory subunit B, beta |
| chr19_-_38720354 | 2.15 |
ENST00000416611.1
|
DPF1
|
D4, zinc and double PHD fingers family 1 |
| chr1_+_64239657 | 2.15 |
ENST00000371080.1
ENST00000371079.1 |
ROR1
|
receptor tyrosine kinase-like orphan receptor 1 |
| chr12_-_10251539 | 2.11 |
ENST00000420265.2
|
CLEC1A
|
C-type lectin domain family 1, member A |
| chr4_-_87028478 | 2.11 |
ENST00000515400.1
ENST00000395157.3 |
MAPK10
|
mitogen-activated protein kinase 10 |
| chr3_+_111260856 | 2.06 |
ENST00000352690.4
|
CD96
|
CD96 molecule |
| chr9_-_16727978 | 2.05 |
ENST00000418777.1
ENST00000468187.2 |
BNC2
|
basonuclin 2 |
| chr2_+_103035102 | 2.03 |
ENST00000264260.2
|
IL18RAP
|
interleukin 18 receptor accessory protein |
| chr10_-_62332357 | 1.99 |
ENST00000503366.1
|
ANK3
|
ankyrin 3, node of Ranvier (ankyrin G) |
| chr4_+_102734967 | 1.97 |
ENST00000444316.2
|
BANK1
|
B-cell scaffold protein with ankyrin repeats 1 |
| chr2_-_70995307 | 1.94 |
ENST00000264436.4
ENST00000355733.3 ENST00000447731.2 ENST00000430656.1 ENST00000413157.2 |
ADD2
|
adducin 2 (beta) |
| chr16_+_72088376 | 1.93 |
ENST00000570083.1
ENST00000355906.5 ENST00000398131.2 ENST00000569639.1 ENST00000564499.1 ENST00000357763.4 ENST00000562526.1 ENST00000565574.1 ENST00000568417.2 ENST00000356967.5 |
HP
HPR
|
haptoglobin haptoglobin-related protein |
| chr1_+_25664408 | 1.91 |
ENST00000374358.4
|
TMEM50A
|
transmembrane protein 50A |
| chr2_+_33172012 | 1.88 |
ENST00000404816.2
|
LTBP1
|
latent transforming growth factor beta binding protein 1 |
| chr7_+_29234028 | 1.88 |
ENST00000222792.6
|
CHN2
|
chimerin 2 |
| chr22_+_40322623 | 1.87 |
ENST00000399090.2
|
GRAP2
|
GRB2-related adaptor protein 2 |
| chr15_-_70390191 | 1.87 |
ENST00000559191.1
|
TLE3
|
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) |
| chr12_+_32260085 | 1.86 |
ENST00000548411.1
ENST00000281474.5 ENST00000551086.1 |
BICD1
|
bicaudal D homolog 1 (Drosophila) |
| chr12_+_132379160 | 1.85 |
ENST00000321867.4
|
ULK1
|
unc-51 like autophagy activating kinase 1 |
| chr3_+_111260954 | 1.81 |
ENST00000283285.5
|
CD96
|
CD96 molecule |
| chr10_+_11047259 | 1.81 |
ENST00000379261.4
ENST00000416382.2 |
CELF2
|
CUGBP, Elav-like family member 2 |
| chrX_-_101726732 | 1.80 |
ENST00000457521.2
ENST00000412230.2 ENST00000453326.2 |
NXF2B
TCP11X2
|
nuclear RNA export factor 2B t-complex 11 family, X-linked 2 |
| chr15_+_41136216 | 1.80 |
ENST00000562057.1
ENST00000344051.4 |
SPINT1
|
serine peptidase inhibitor, Kunitz type 1 |
| chr10_+_17272608 | 1.80 |
ENST00000421459.2
|
VIM
|
vimentin |
| chr14_+_91580732 | 1.78 |
ENST00000519019.1
ENST00000523816.1 ENST00000517518.1 |
C14orf159
|
chromosome 14 open reading frame 159 |
| chr14_+_91580777 | 1.73 |
ENST00000525393.2
ENST00000428926.2 ENST00000517362.1 |
C14orf159
|
chromosome 14 open reading frame 159 |
| chr2_+_11679963 | 1.67 |
ENST00000263834.5
|
GREB1
|
growth regulation by estrogen in breast cancer 1 |
| chr8_+_24151553 | 1.66 |
ENST00000265769.4
ENST00000540823.1 ENST00000397649.3 |
ADAM28
|
ADAM metallopeptidase domain 28 |
| chr22_+_40322595 | 1.66 |
ENST00000420971.1
ENST00000544756.1 |
GRAP2
|
GRB2-related adaptor protein 2 |
| chr8_-_17579726 | 1.65 |
ENST00000381861.3
|
MTUS1
|
microtubule associated tumor suppressor 1 |
| chr20_-_56284816 | 1.62 |
ENST00000395819.3
ENST00000341744.3 |
PMEPA1
|
prostate transmembrane protein, androgen induced 1 |
| chr16_+_54964740 | 1.62 |
ENST00000394636.4
|
IRX5
|
iroquois homeobox 5 |
| chr22_-_31688431 | 1.56 |
ENST00000402249.3
ENST00000443175.1 ENST00000215912.5 ENST00000441972.1 |
PIK3IP1
|
phosphoinositide-3-kinase interacting protein 1 |
| chr8_-_70745575 | 1.56 |
ENST00000524945.1
|
SLCO5A1
|
solute carrier organic anion transporter family, member 5A1 |
| chr12_-_10151773 | 1.53 |
ENST00000298527.6
ENST00000348658.4 |
CLEC1B
|
C-type lectin domain family 1, member B |
| chr6_+_22146851 | 1.51 |
ENST00000606197.1
|
CASC15
|
cancer susceptibility candidate 15 (non-protein coding) |
| chrX_+_101470280 | 1.50 |
ENST00000395088.2
ENST00000330252.5 ENST00000333110.5 |
NXF2
TCP11X1
|
nuclear RNA export factor 2 t-complex 11 family, X-linked 1 |
| chr20_-_17511962 | 1.47 |
ENST00000377873.3
|
BFSP1
|
beaded filament structural protein 1, filensin |
| chr8_-_16043780 | 1.41 |
ENST00000445506.2
|
MSR1
|
macrophage scavenger receptor 1 |
| chr14_-_20923195 | 1.41 |
ENST00000206542.4
|
OSGEP
|
O-sialoglycoprotein endopeptidase |
| chr7_+_107110488 | 1.39 |
ENST00000304402.4
|
GPR22
|
G protein-coupled receptor 22 |
| chr10_+_11206925 | 1.38 |
ENST00000354440.2
ENST00000315874.4 ENST00000427450.1 |
CELF2
|
CUGBP, Elav-like family member 2 |
| chrX_-_2847366 | 1.34 |
ENST00000381154.1
|
ARSD
|
arylsulfatase D |
| chr3_+_181429704 | 1.32 |
ENST00000431565.2
ENST00000325404.1 |
SOX2
|
SRY (sex determining region Y)-box 2 |
| chr6_-_27440837 | 1.32 |
ENST00000211936.6
|
ZNF184
|
zinc finger protein 184 |
| chr20_+_45338126 | 1.31 |
ENST00000359271.2
|
SLC2A10
|
solute carrier family 2 (facilitated glucose transporter), member 10 |
| chr10_-_61900762 | 1.30 |
ENST00000355288.2
|
ANK3
|
ankyrin 3, node of Ranvier (ankyrin G) |
| chr6_-_27440460 | 1.28 |
ENST00000377419.1
|
ZNF184
|
zinc finger protein 184 |
| chr12_+_70760056 | 1.28 |
ENST00000258111.4
|
KCNMB4
|
potassium large conductance calcium-activated channel, subfamily M, beta member 4 |
| chr5_-_111091948 | 1.27 |
ENST00000447165.2
|
NREP
|
neuronal regeneration related protein |
| chr5_-_175964366 | 1.26 |
ENST00000274811.4
|
RNF44
|
ring finger protein 44 |
| chr14_+_91580708 | 1.25 |
ENST00000518868.1
|
C14orf159
|
chromosome 14 open reading frame 159 |
| chr8_-_6783588 | 1.24 |
ENST00000297436.2
|
DEFA6
|
defensin, alpha 6, Paneth cell-specific |
| chr1_+_207002222 | 1.22 |
ENST00000270218.6
|
IL19
|
interleukin 19 |
| chr1_+_28261533 | 1.17 |
ENST00000411604.1
ENST00000373888.4 |
SMPDL3B
|
sphingomyelin phosphodiesterase, acid-like 3B |
| chr12_-_10282742 | 1.14 |
ENST00000298523.5
ENST00000396484.2 ENST00000310002.4 |
CLEC7A
|
C-type lectin domain family 7, member A |
| chr8_+_79428539 | 1.09 |
ENST00000352966.5
|
PKIA
|
protein kinase (cAMP-dependent, catalytic) inhibitor alpha |
| chr14_+_32798462 | 1.06 |
ENST00000280979.4
|
AKAP6
|
A kinase (PRKA) anchor protein 6 |
| chr14_+_91580357 | 1.05 |
ENST00000298858.4
ENST00000521081.1 ENST00000520328.1 ENST00000256324.10 ENST00000524232.1 ENST00000522170.1 ENST00000519950.1 ENST00000523879.1 ENST00000521077.2 ENST00000518665.2 |
C14orf159
|
chromosome 14 open reading frame 159 |
| chr1_-_167487808 | 1.01 |
ENST00000392122.3
|
CD247
|
CD247 molecule |
| chr5_+_102201430 | 0.99 |
ENST00000438793.3
ENST00000346918.2 |
PAM
|
peptidylglycine alpha-amidating monooxygenase |
| chr16_-_3068171 | 0.98 |
ENST00000572154.1
ENST00000328796.4 |
CLDN6
|
claudin 6 |
| chr11_-_10829851 | 0.97 |
ENST00000532082.1
|
EIF4G2
|
eukaryotic translation initiation factor 4 gamma, 2 |
| chr2_-_136594740 | 0.96 |
ENST00000264162.2
|
LCT
|
lactase |
| chr1_-_93645818 | 0.95 |
ENST00000370280.1
ENST00000479918.1 |
TMED5
|
transmembrane emp24 protein transport domain containing 5 |
| chr14_+_32798547 | 0.94 |
ENST00000557354.1
ENST00000557102.1 ENST00000557272.1 |
AKAP6
|
A kinase (PRKA) anchor protein 6 |
| chr12_+_109915179 | 0.94 |
ENST00000434735.2
|
UBE3B
|
ubiquitin protein ligase E3B |
| chr7_+_20370300 | 0.91 |
ENST00000537992.1
|
ITGB8
|
integrin, beta 8 |
| chr8_-_42623924 | 0.87 |
ENST00000276410.2
|
CHRNA6
|
cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| chr15_-_74495188 | 0.86 |
ENST00000563965.1
ENST00000395105.4 |
STRA6
|
stimulated by retinoic acid 6 |
| chr3_-_197024965 | 0.85 |
ENST00000392382.2
|
DLG1
|
discs, large homolog 1 (Drosophila) |
| chr4_-_109089573 | 0.85 |
ENST00000265165.1
|
LEF1
|
lymphoid enhancer-binding factor 1 |
| chr3_-_3152031 | 0.79 |
ENST00000383846.1
ENST00000427088.1 ENST00000446632.2 ENST00000438560.1 |
IL5RA
|
interleukin 5 receptor, alpha |
| chr19_+_49128209 | 0.75 |
ENST00000599748.1
ENST00000443164.1 ENST00000599029.1 |
SPHK2
|
sphingosine kinase 2 |
| chr1_-_167487758 | 0.75 |
ENST00000362089.5
|
CD247
|
CD247 molecule |
| chr15_+_50474412 | 0.74 |
ENST00000380902.4
|
SLC27A2
|
solute carrier family 27 (fatty acid transporter), member 2 |
| chr15_+_41136586 | 0.74 |
ENST00000431806.1
|
SPINT1
|
serine peptidase inhibitor, Kunitz type 1 |
| chr5_+_140787600 | 0.71 |
ENST00000520790.1
|
PCDHGB6
|
protocadherin gamma subfamily B, 6 |
| chr14_+_91581011 | 0.70 |
ENST00000523894.1
ENST00000522322.1 ENST00000523771.1 |
C14orf159
|
chromosome 14 open reading frame 159 |
| chr18_+_6729725 | 0.67 |
ENST00000400091.2
ENST00000583410.1 ENST00000584387.1 |
ARHGAP28
|
Rho GTPase activating protein 28 |
| chr1_+_66458072 | 0.65 |
ENST00000423207.2
|
PDE4B
|
phosphodiesterase 4B, cAMP-specific |
| chr22_+_27017921 | 0.64 |
ENST00000354760.3
|
CRYBA4
|
crystallin, beta A4 |
| chr7_-_150946015 | 0.61 |
ENST00000262188.8
|
SMARCD3
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| chr22_-_31688381 | 0.60 |
ENST00000487265.2
|
PIK3IP1
|
phosphoinositide-3-kinase interacting protein 1 |
| chr17_+_9066252 | 0.58 |
ENST00000436734.1
|
NTN1
|
netrin 1 |
| chr4_+_78079570 | 0.58 |
ENST00000509972.1
|
CCNG2
|
cyclin G2 |
| chr4_+_71588372 | 0.53 |
ENST00000536664.1
|
RUFY3
|
RUN and FYVE domain containing 3 |
| chr15_-_70390213 | 0.50 |
ENST00000557997.1
ENST00000317509.8 ENST00000442299.2 |
TLE3
|
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) |
| chr1_-_243418344 | 0.49 |
ENST00000366542.1
|
CEP170
|
centrosomal protein 170kDa |
| chr5_+_140480083 | 0.46 |
ENST00000231130.2
|
PCDHB3
|
protocadherin beta 3 |
| chr19_+_10765699 | 0.44 |
ENST00000590009.1
|
ILF3
|
interleukin enhancer binding factor 3, 90kDa |
| chr14_-_61124977 | 0.44 |
ENST00000554986.1
|
SIX1
|
SIX homeobox 1 |
| chr7_+_134551583 | 0.43 |
ENST00000435928.1
|
CALD1
|
caldesmon 1 |
| chr15_+_50474385 | 0.42 |
ENST00000267842.5
|
SLC27A2
|
solute carrier family 27 (fatty acid transporter), member 2 |
| chrX_-_110654147 | 0.42 |
ENST00000358070.4
|
DCX
|
doublecortin |
Network of associatons between targets according to the STRING database.
First level regulatory network of SOX4
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.1 | 20.5 | GO:0035026 | leading edge cell differentiation(GO:0035026) |
| 2.7 | 8.0 | GO:0035283 | rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284) |
| 2.2 | 11.2 | GO:0044856 | plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906) |
| 2.1 | 16.8 | GO:0001661 | conditioned taste aversion(GO:0001661) |
| 2.1 | 8.2 | GO:0061304 | retinal blood vessel morphogenesis(GO:0061304) |
| 2.1 | 8.2 | GO:0031117 | positive regulation of microtubule depolymerization(GO:0031117) |
| 1.5 | 7.5 | GO:1904209 | regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) |
| 1.3 | 9.4 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
| 1.3 | 3.9 | GO:0002370 | natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727) |
| 1.3 | 16.6 | GO:0033617 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 1.3 | 3.8 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
| 1.1 | 12.0 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 0.9 | 2.8 | GO:0006001 | fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) |
| 0.9 | 13.2 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
| 0.8 | 2.5 | GO:0021798 | forebrain dorsal/ventral pattern formation(GO:0021798) |
| 0.8 | 3.3 | GO:0072658 | positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.8 | 3.2 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
| 0.7 | 5.2 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
| 0.7 | 2.2 | GO:0090219 | negative regulation of lipid kinase activity(GO:0090219) |
| 0.7 | 10.8 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
| 0.7 | 2.6 | GO:0045763 | negative regulation of cellular amino acid metabolic process(GO:0045763) regulation of glutamate metabolic process(GO:2000211) |
| 0.6 | 1.9 | GO:2000296 | negative regulation of hydrogen peroxide catabolic process(GO:2000296) |
| 0.6 | 2.6 | GO:0001970 | positive regulation of activation of membrane attack complex(GO:0001970) |
| 0.6 | 4.5 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.6 | 5.9 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.5 | 8.7 | GO:0090361 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 0.5 | 5.3 | GO:1901223 | negative regulation of NIK/NF-kappaB signaling(GO:1901223) |
| 0.5 | 4.1 | GO:0030323 | respiratory tube development(GO:0030323) |
| 0.5 | 12.7 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.5 | 2.0 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
| 0.5 | 1.4 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 0.5 | 4.2 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.4 | 4.8 | GO:0006032 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
| 0.4 | 1.6 | GO:0060040 | retinal bipolar neuron differentiation(GO:0060040) |
| 0.4 | 5.2 | GO:0047484 | regulation of response to osmotic stress(GO:0047484) |
| 0.4 | 3.5 | GO:0030091 | protein repair(GO:0030091) |
| 0.4 | 1.9 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
| 0.4 | 4.3 | GO:0048263 | determination of dorsal identity(GO:0048263) |
| 0.3 | 3.4 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.3 | 1.3 | GO:0031179 | peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179) |
| 0.3 | 2.2 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.3 | 5.7 | GO:0003351 | epithelial cilium movement(GO:0003351) |
| 0.3 | 3.2 | GO:1904424 | regulation of GTP binding(GO:1904424) |
| 0.3 | 7.3 | GO:0070262 | peptidyl-serine dephosphorylation(GO:0070262) |
| 0.3 | 2.5 | GO:0034128 | negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128) |
| 0.3 | 3.0 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 0.3 | 1.2 | GO:0097089 | methyl-branched fatty acid metabolic process(GO:0097089) |
| 0.3 | 23.8 | GO:0006826 | iron ion transport(GO:0006826) |
| 0.3 | 3.7 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.3 | 4.7 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.3 | 3.8 | GO:0042574 | retinal metabolic process(GO:0042574) |
| 0.3 | 1.8 | GO:0075044 | autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071) |
| 0.3 | 2.1 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.3 | 0.8 | GO:0038043 | interleukin-5-mediated signaling pathway(GO:0038043) |
| 0.3 | 5.2 | GO:0009756 | carbohydrate mediated signaling(GO:0009756) |
| 0.3 | 0.8 | GO:0006669 | sphinganine-1-phosphate biosynthetic process(GO:0006669) |
| 0.2 | 2.0 | GO:1900165 | negative regulation of interleukin-6 secretion(GO:1900165) |
| 0.2 | 4.1 | GO:0098828 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.2 | 1.3 | GO:0001714 | endodermal cell fate specification(GO:0001714) |
| 0.2 | 3.3 | GO:0070307 | lens fiber cell development(GO:0070307) |
| 0.2 | 1.0 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 0.2 | 6.7 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.2 | 0.9 | GO:0061143 | alveolar primary septum development(GO:0061143) |
| 0.2 | 5.4 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.2 | 6.5 | GO:0006536 | glutamate metabolic process(GO:0006536) |
| 0.2 | 4.6 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.2 | 2.5 | GO:0051531 | NFAT protein import into nucleus(GO:0051531) |
| 0.2 | 10.4 | GO:0045540 | regulation of cholesterol biosynthetic process(GO:0045540) |
| 0.1 | 4.5 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.1 | 0.9 | GO:1903760 | regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) |
| 0.1 | 0.1 | GO:0006542 | glutamine biosynthetic process(GO:0006542) |
| 0.1 | 2.7 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.1 | 0.4 | GO:0071699 | olfactory placode formation(GO:0030910) myotome development(GO:0061055) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729) |
| 0.1 | 0.7 | GO:0071895 | odontoblast differentiation(GO:0071895) |
| 0.1 | 2.5 | GO:0060670 | branching involved in labyrinthine layer morphogenesis(GO:0060670) |
| 0.1 | 1.6 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.1 | 4.4 | GO:0042744 | hydrogen peroxide catabolic process(GO:0042744) |
| 0.1 | 3.8 | GO:0036152 | phosphatidylethanolamine acyl-chain remodeling(GO:0036152) |
| 0.1 | 0.6 | GO:0003219 | cardiac right ventricle formation(GO:0003219) |
| 0.1 | 2.0 | GO:0043586 | tongue development(GO:0043586) |
| 0.1 | 2.3 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.1 | 0.6 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
| 0.1 | 4.3 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 0.1 | 2.6 | GO:0000729 | DNA double-strand break processing(GO:0000729) |
| 0.1 | 1.4 | GO:0010886 | positive regulation of cholesterol storage(GO:0010886) |
| 0.1 | 5.0 | GO:0034308 | primary alcohol metabolic process(GO:0034308) |
| 0.1 | 1.2 | GO:0042226 | interleukin-6 biosynthetic process(GO:0042226) |
| 0.1 | 6.6 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.1 | 11.0 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.1 | 1.3 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.1 | 1.5 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
| 0.1 | 2.1 | GO:0014002 | astrocyte development(GO:0014002) |
| 0.1 | 1.9 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
| 0.1 | 2.6 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.1 | 1.1 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.1 | 1.5 | GO:0030220 | platelet formation(GO:0030220) |
| 0.1 | 3.2 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.1 | 0.9 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.1 | 2.3 | GO:0035116 | embryonic hindlimb morphogenesis(GO:0035116) |
| 0.1 | 2.4 | GO:1904837 | beta-catenin-TCF complex assembly(GO:1904837) |
| 0.1 | 0.7 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
| 0.1 | 1.8 | GO:0070207 | protein homotrimerization(GO:0070207) |
| 0.0 | 0.9 | GO:0001573 | ganglioside metabolic process(GO:0001573) |
| 0.0 | 3.5 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.0 | 1.3 | GO:0035428 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 0.0 | 1.2 | GO:0050832 | defense response to fungus(GO:0050832) |
| 0.0 | 3.5 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
| 0.0 | 1.0 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.0 | 1.3 | GO:0006687 | glycosphingolipid metabolic process(GO:0006687) |
| 0.0 | 1.1 | GO:0000209 | protein polyubiquitination(GO:0000209) |
| 0.0 | 0.3 | GO:0009303 | rRNA transcription(GO:0009303) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.3 | 20.5 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 2.1 | 12.7 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 2.1 | 16.8 | GO:0035976 | AP1 complex(GO:0035976) |
| 1.5 | 14.8 | GO:0098651 | basement membrane collagen trimer(GO:0098651) |
| 1.1 | 3.2 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
| 1.1 | 7.5 | GO:0033269 | internode region of axon(GO:0033269) |
| 1.1 | 5.3 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.9 | 10.4 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.8 | 4.6 | GO:1990769 | proximal neuron projection(GO:1990769) |
| 0.8 | 13.0 | GO:0005687 | U4 snRNP(GO:0005687) |
| 0.7 | 10.5 | GO:0030478 | actin cap(GO:0030478) |
| 0.6 | 2.5 | GO:1990578 | perinuclear endoplasmic reticulum membrane(GO:1990578) |
| 0.6 | 1.8 | GO:1903349 | omegasome membrane(GO:1903349) |
| 0.6 | 5.0 | GO:0005638 | lamin filament(GO:0005638) |
| 0.5 | 1.9 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.4 | 1.9 | GO:0033655 | host cell cytoplasm(GO:0030430) host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648) host cell cytoplasm part(GO:0033655) tubulin complex(GO:0045298) |
| 0.3 | 0.9 | GO:0034686 | integrin alphav-beta8 complex(GO:0034686) |
| 0.3 | 1.5 | GO:0042272 | nuclear RNA export factor complex(GO:0042272) |
| 0.3 | 2.0 | GO:0014701 | junctional sarcoplasmic reticulum membrane(GO:0014701) |
| 0.3 | 2.6 | GO:0005579 | membrane attack complex(GO:0005579) |
| 0.3 | 7.1 | GO:0071565 | nBAF complex(GO:0071565) |
| 0.3 | 1.4 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.3 | 2.2 | GO:0000322 | storage vacuole(GO:0000322) |
| 0.2 | 7.3 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.2 | 3.3 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.2 | 4.2 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.2 | 1.8 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.1 | 2.5 | GO:0005922 | connexon complex(GO:0005922) |
| 0.1 | 13.2 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.1 | 12.0 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.1 | 2.8 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.1 | 23.0 | GO:0030426 | growth cone(GO:0030426) |
| 0.1 | 0.9 | GO:0043219 | lateral loop(GO:0043219) |
| 0.1 | 2.3 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.1 | 2.5 | GO:0031312 | extrinsic component of organelle membrane(GO:0031312) |
| 0.1 | 4.1 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.1 | 9.4 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.1 | 2.5 | GO:0016592 | mediator complex(GO:0016592) |
| 0.1 | 0.7 | GO:1990907 | beta-catenin-TCF complex(GO:1990907) |
| 0.1 | 4.8 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.1 | 8.7 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.1 | 7.1 | GO:0044853 | plasma membrane raft(GO:0044853) |
| 0.1 | 1.4 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
| 0.0 | 0.9 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.0 | 1.0 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 4.5 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.0 | 19.2 | GO:0031966 | mitochondrial membrane(GO:0031966) |
| 0.0 | 0.7 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.0 | 6.4 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 3.6 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 3.5 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 6.8 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 36.9 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.0 | 4.2 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 1.7 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 9.7 | GO:0005794 | Golgi apparatus(GO:0005794) |
| 0.0 | 34.2 | GO:0016021 | integral component of membrane(GO:0016021) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.0 | 17.9 | GO:0030350 | iron-responsive element binding(GO:0030350) |
| 1.7 | 20.7 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 1.6 | 4.7 | GO:0036134 | thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134) |
| 1.3 | 6.5 | GO:0047820 | D-glutamate cyclase activity(GO:0047820) |
| 1.0 | 8.2 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
| 0.9 | 3.8 | GO:0005502 | 11-cis retinal binding(GO:0005502) |
| 0.9 | 20.5 | GO:0098748 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.9 | 11.2 | GO:0045159 | myosin II binding(GO:0045159) |
| 0.9 | 4.4 | GO:0005152 | interleukin-1 receptor antagonist activity(GO:0005152) |
| 0.8 | 4.2 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.7 | 3.5 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
| 0.6 | 3.2 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
| 0.6 | 5.4 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.6 | 5.9 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.6 | 3.0 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.6 | 3.4 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
| 0.6 | 2.2 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
| 0.5 | 12.0 | GO:0016769 | transferase activity, transferring nitrogenous groups(GO:0016769) |
| 0.5 | 3.8 | GO:0047144 | 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144) |
| 0.5 | 1.9 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.4 | 2.7 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.4 | 4.8 | GO:0008061 | chitinase activity(GO:0004568) chitin binding(GO:0008061) |
| 0.4 | 5.2 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
| 0.4 | 2.6 | GO:0008310 | single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) |
| 0.4 | 10.7 | GO:0005521 | lamin binding(GO:0005521) |
| 0.4 | 18.5 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.4 | 2.1 | GO:1904929 | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
| 0.4 | 2.1 | GO:0004705 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.3 | 1.9 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 0.3 | 1.0 | GO:0008422 | beta-glucosidase activity(GO:0008422) |
| 0.3 | 1.3 | GO:0004504 | peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598) |
| 0.3 | 2.5 | GO:0043559 | insulin binding(GO:0043559) |
| 0.3 | 1.8 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.3 | 1.6 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.3 | 0.8 | GO:0004914 | interleukin-5 receptor activity(GO:0004914) |
| 0.3 | 2.8 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.2 | 9.4 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.2 | 5.7 | GO:0004016 | adenylate cyclase activity(GO:0004016) |
| 0.2 | 5.2 | GO:0008329 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
| 0.2 | 0.9 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.2 | 5.0 | GO:0004622 | lysophospholipase activity(GO:0004622) |
| 0.2 | 4.5 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.2 | 4.5 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.2 | 2.5 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.2 | 6.7 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.1 | 2.0 | GO:0008179 | adenylate cyclase binding(GO:0008179) protein anchor(GO:0043495) |
| 0.1 | 4.3 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.1 | 4.6 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.1 | 0.8 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
| 0.1 | 12.5 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.1 | 4.3 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
| 0.1 | 5.2 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.1 | 7.2 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.1 | 8.2 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.1 | 1.3 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.1 | 1.3 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 0.1 | 2.2 | GO:0043548 | phosphatidylinositol 3-kinase binding(GO:0043548) |
| 0.1 | 1.2 | GO:0015245 | fatty acid transporter activity(GO:0015245) |
| 0.1 | 1.4 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
| 0.1 | 0.9 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.1 | 7.3 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.1 | 1.3 | GO:0035198 | miRNA binding(GO:0035198) |
| 0.1 | 2.6 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 3.2 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.1 | 1.1 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.1 | 2.3 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
| 0.0 | 4.6 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 1.3 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.0 | 4.1 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 0.7 | GO:0030284 | estrogen receptor activity(GO:0030284) |
| 0.0 | 5.2 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.0 | 10.0 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.0 | 0.1 | GO:0016880 | glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880) |
| 0.0 | 2.5 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.0 | 2.6 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.0 | 0.9 | GO:0051183 | vitamin transporter activity(GO:0051183) |
| 0.0 | 0.4 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.0 | 2.5 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 3.7 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.7 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 0.6 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 2.0 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 1.0 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.0 | 1.1 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 30.5 | PID AVB3 OPN PATHWAY | Osteopontin-mediated events |
| 0.3 | 13.9 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.2 | 2.6 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.2 | 20.5 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.2 | 3.5 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.2 | 2.7 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.1 | 22.9 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 15.0 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 7.1 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.1 | 6.1 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 0.1 | 3.8 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.1 | 0.8 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.1 | 2.1 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.1 | 5.4 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.1 | 2.2 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.1 | 1.8 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.1 | 2.8 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 0.9 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 1.2 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.0 | 2.5 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 0.9 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 6.7 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 1.0 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 0.1 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.0 | 4.5 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 0.6 | PID LKB1 PATHWAY | LKB1 signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 20.5 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.9 | 19.0 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.7 | 10.4 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.4 | 4.6 | REACTOME REGULATION OF INSULIN SECRETION | Genes involved in Regulation of Insulin Secretion |
| 0.4 | 13.0 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.2 | 4.1 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.2 | 13.9 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.2 | 4.6 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.2 | 3.8 | REACTOME ACYL CHAIN REMODELLING OF PE | Genes involved in Acyl chain remodelling of PE |
| 0.1 | 2.5 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.1 | 2.7 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.1 | 2.5 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.1 | 5.3 | REACTOME GROWTH HORMONE RECEPTOR SIGNALING | Genes involved in Growth hormone receptor signaling |
| 0.1 | 1.2 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.1 | 5.3 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.1 | 3.3 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 5.3 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.1 | 1.0 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.1 | 4.7 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.1 | 1.2 | REACTOME DEFENSINS | Genes involved in Defensins |
| 0.1 | 2.8 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.1 | 0.6 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 0.1 | 9.4 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 3.2 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.1 | 3.2 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.1 | 1.3 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.1 | 2.6 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 0.0 | 3.9 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 1.6 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 6.9 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 4.3 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 2.4 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 1.3 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 0.6 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.0 | 1.0 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 0.8 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.0 | 0.9 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 1.0 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 0.8 | REACTOME SPHINGOLIPID METABOLISM | Genes involved in Sphingolipid metabolism |
| 0.0 | 0.7 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 4.1 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |