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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for SP4_PML

Z-value: 1.59

Motif logo

Transcription factors associated with SP4_PML

Gene Symbol Gene ID Gene Info
ENSG00000105866.9 Sp4 transcription factor
ENSG00000140464.15 PML nuclear body scaffold

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PMLhg19_v2_chr15_+_74287118_74287144-0.221.3e-03Click!
SP4hg19_v2_chr7_+_21467642_21467671-0.136.4e-02Click!

Activity profile of SP4_PML motif

Sorted Z-values of SP4_PML motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_23618582 45.27 ENST00000398411.1
ENST00000376925.3
cystatin C
chr5_+_17217669 44.87 ENST00000322611.3
brain abundant, membrane attached signal protein 1
chr1_-_20812690 42.12 ENST00000375078.3
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr2_-_175869936 38.87 ENST00000409900.3
chimerin 1
chr11_-_12030629 38.33 ENST00000396505.2
dickkopf WNT signaling pathway inhibitor 3
chr12_-_124457257 36.72 ENST00000545891.1
coiled-coil domain containing 92
chr3_-_149688502 36.56 ENST00000481767.1
ENST00000475518.1
profilin 2
chr18_-_74844727 35.81 ENST00000355994.2
ENST00000579129.1
myelin basic protein
chr10_-_15413035 35.35 ENST00000378116.4
ENST00000455654.1
family with sequence similarity 171, member A1
chr9_+_137979506 35.08 ENST00000539529.1
ENST00000392991.4
ENST00000371793.3
olfactomedin 1
chr2_-_175870085 34.87 ENST00000409156.3
chimerin 1
chr3_-_149688655 33.70 ENST00000461930.1
ENST00000423691.2
ENST00000490975.1
ENST00000461868.1
ENST00000452853.2
profilin 2
chr19_-_19006890 33.66 ENST00000247005.6
growth differentiation factor 1
chr11_-_134281812 33.14 ENST00000392580.1
ENST00000312527.4
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr1_+_169075554 33.03 ENST00000367815.4
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr19_+_708910 32.48 ENST00000264560.7
paralemmin
chr9_+_139873264 32.31 ENST00000446677.1
prostaglandin D2 synthase 21kDa (brain)
chr8_+_1922024 31.77 ENST00000320248.3
kelch repeat and BTB (POZ) domain containing 11
chr19_+_709101 31.68 ENST00000338448.5
paralemmin
chr19_-_19006920 31.26 ENST00000429504.2
ENST00000427170.2
ceramide synthase 1
chr1_+_6845384 30.86 ENST00000303635.7
calmodulin binding transcription activator 1
chr16_+_58497567 30.73 ENST00000258187.5
NDRG family member 4
chr13_-_110438914 30.41 ENST00000375856.3
insulin receptor substrate 2
chr20_-_50385138 29.62 ENST00000338821.5
ATPase, class II, type 9A
chr20_-_62130474 29.54 ENST00000217182.3
eukaryotic translation elongation factor 1 alpha 2
chr11_-_12030905 28.88 ENST00000326932.4
dickkopf WNT signaling pathway inhibitor 3
chrX_+_153665248 28.76 ENST00000447750.2
GDP dissociation inhibitor 1
chr2_+_181845298 27.99 ENST00000410062.4
ubiquitin-conjugating enzyme E2E 3
chr12_-_118498958 27.21 ENST00000315436.3
WD repeat and SOCS box containing 2
chr12_-_124457371 27.05 ENST00000238156.3
ENST00000545037.1
coiled-coil domain containing 92
chr22_-_39239987 27.05 ENST00000333039.2
neuronal pentraxin receptor
chr4_+_166128735 25.89 ENST00000226725.6
kelch-like family member 2
chr15_+_80696666 25.57 ENST00000303329.4
aryl-hydrocarbon receptor nuclear translocator 2
chr20_-_50384864 25.34 ENST00000311637.5
ENST00000402822.1
ATPase, class II, type 9A
chr14_+_100437780 25.07 ENST00000402714.2
Enah/Vasp-like
chr5_-_693500 25.03 ENST00000360578.5
tubulin polymerization promoting protein
chr6_+_107811162 24.83 ENST00000317357.5
sine oculis binding protein homolog (Drosophila)
chr14_-_60337684 24.62 ENST00000267484.5
reticulon 1
chr2_-_224903995 24.23 ENST00000409304.1
ENST00000454956.1
ENST00000258405.4
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr7_-_158380371 23.84 ENST00000389418.4
ENST00000389416.4
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr10_+_11060004 23.76 ENST00000542579.1
ENST00000399850.3
ENST00000417956.2
CUGBP, Elav-like family member 2
chr3_-_149688896 23.73 ENST00000239940.7
profilin 2
chr22_+_32340447 23.69 ENST00000248975.5
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr15_+_68871308 23.67 ENST00000261861.5
coronin, actin binding protein, 2B
chr8_-_103136481 23.66 ENST00000524209.1
ENST00000517822.1
ENST00000523923.1
ENST00000521599.1
ENST00000521964.1
ENST00000311028.3
ENST00000518166.1
neurocalcin delta
chr6_+_17393839 23.61 ENST00000489374.1
ENST00000378990.2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr7_-_51384451 23.52 ENST00000441453.1
ENST00000265136.7
ENST00000395542.2
ENST00000395540.2
cordon-bleu WH2 repeat protein
chr10_-_75634326 23.18 ENST00000322635.3
ENST00000444854.2
ENST00000423381.1
ENST00000322680.3
ENST00000394762.2
calcium/calmodulin-dependent protein kinase II gamma
chr1_+_1981890 23.18 ENST00000378567.3
ENST00000468310.1
protein kinase C, zeta
chr16_+_2039946 23.14 ENST00000248121.2
ENST00000568896.1
synaptogyrin 3
chr13_-_45150392 22.91 ENST00000501704.2
TSC22 domain family, member 1
chr15_+_29131103 22.26 ENST00000558402.1
ENST00000558330.1
amyloid beta (A4) precursor protein-binding, family A, member 2
chr22_-_44258360 22.21 ENST00000330884.4
ENST00000249130.5
sulfotransferase family 4A, member 1
chr8_+_26371763 22.18 ENST00000521913.1
dihydropyrimidinase-like 2
chr17_-_1083078 22.13 ENST00000574266.1
ENST00000302538.5
active BCR-related
chr22_+_32340481 21.91 ENST00000397492.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr1_-_1822495 21.46 ENST00000378609.4
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr7_-_158380465 21.40 ENST00000389413.3
ENST00000409483.1
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr22_-_45636650 21.31 ENST00000336156.5
KIAA0930
chr16_+_11762270 21.28 ENST00000329565.5
stannin
chr12_-_123755639 21.23 ENST00000535979.1
cyclin-dependent kinase 2 associated protein 1
chr14_+_29236269 21.17 ENST00000313071.4
forkhead box G1
chr12_-_121734489 21.10 ENST00000412367.2
ENST00000402834.4
ENST00000404169.3
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr20_+_44034804 20.95 ENST00000357275.2
ENST00000372720.3
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr4_-_102268484 20.82 ENST00000394853.4
protein phosphatase 3, catalytic subunit, alpha isozyme
chr10_+_121485588 20.77 ENST00000361976.2
ENST00000369083.3
inositol polyphosphate-5-phosphatase F
chr9_-_139922726 20.44 ENST00000265662.5
ENST00000371605.3
ATP-binding cassette, sub-family A (ABC1), member 2
chr20_+_44034676 20.39 ENST00000372723.3
ENST00000372722.3
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr8_-_30670053 20.33 ENST00000518564.1
protein phosphatase 2, catalytic subunit, beta isozyme
chr1_-_241520525 20.27 ENST00000366565.1
regulator of G-protein signaling 7
chr11_+_46354455 20.20 ENST00000343674.6
diacylglycerol kinase, zeta
chr10_+_124221036 20.20 ENST00000368984.3
HtrA serine peptidase 1
chr15_+_68871569 20.16 ENST00000566799.1
coronin, actin binding protein, 2B
chr9_+_137967366 20.14 ENST00000252854.4
olfactomedin 1
chr19_-_6502590 20.02 ENST00000264071.2
tubulin, beta 4A class IVa
chr10_-_75634219 20.02 ENST00000305762.7
calcium/calmodulin-dependent protein kinase II gamma
chr6_-_3157760 19.70 ENST00000333628.3
tubulin, beta 2A class IIa
chr17_+_40118805 19.70 ENST00000591072.1
ENST00000587679.1
ENST00000393888.1
ENST00000441615.2
2',3'-cyclic nucleotide 3' phosphodiesterase
chr16_+_56225248 19.69 ENST00000262493.6
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr6_-_29600832 19.63 ENST00000377016.4
ENST00000376977.3
ENST00000377034.4
gamma-aminobutyric acid (GABA) B receptor, 1
chr10_-_75634260 19.57 ENST00000372765.1
ENST00000351293.3
calcium/calmodulin-dependent protein kinase II gamma
chr4_-_1242764 19.54 ENST00000514210.1
ENST00000382952.3
ENST00000290921.6
C-terminal binding protein 1
chr19_-_6502304 19.54 ENST00000540257.1
ENST00000594276.1
ENST00000594075.1
ENST00000600216.1
ENST00000596926.1
tubulin, beta 4A class IVa
chr17_+_30813576 19.46 ENST00000313401.3
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr6_+_17393888 19.45 ENST00000493172.1
ENST00000465994.1
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr20_+_4666882 19.43 ENST00000379440.4
ENST00000430350.2
prion protein
chr6_-_46459099 19.38 ENST00000371374.1
regulator of calcineurin 2
chr7_+_149571045 19.36 ENST00000479613.1
ENST00000606024.1
ENST00000464662.1
ENST00000425642.2
ATPase, H+ transporting V0 subunit e2
chr20_+_11871433 19.31 ENST00000399006.2
ENST00000405977.1
BTB (POZ) domain containing 3
chr7_-_30029574 19.29 ENST00000426154.1
ENST00000421434.1
ENST00000434476.2
secernin 1
chr11_-_9286921 19.22 ENST00000328194.3
DENN/MADD domain containing 5A
chr17_-_42992856 19.17 ENST00000588316.1
ENST00000435360.2
ENST00000586793.1
ENST00000588735.1
ENST00000588037.1
ENST00000592320.1
ENST00000253408.5
glial fibrillary acidic protein
chr7_-_38671098 19.12 ENST00000356264.2
amphiphysin
chr7_-_38670957 19.10 ENST00000325590.5
ENST00000428293.2
amphiphysin
chr8_-_18871159 19.05 ENST00000327040.8
ENST00000440756.2
pleckstrin and Sec7 domain containing 3
chr1_-_32229934 18.98 ENST00000398542.1
brain-specific angiogenesis inhibitor 2
chr2_-_235405679 18.95 ENST00000390645.2
ADP-ribosylation factor-like 4C
chrX_-_13956737 18.87 ENST00000454189.2
glycoprotein M6B
chr4_+_6784401 18.86 ENST00000425103.1
ENST00000307659.5
KIAA0232
chr1_-_9884011 18.78 ENST00000361311.4
calsyntenin 1
chr12_+_7023735 18.65 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
enolase 2 (gamma, neuronal)
chr1_+_77747656 18.54 ENST00000354567.2
adenylate kinase 5
chr12_+_7023491 18.44 ENST00000541477.1
ENST00000229277.1
enolase 2 (gamma, neuronal)
chr14_-_74181106 18.42 ENST00000316836.3
paraneoplastic Ma antigen 1
chr16_+_2563871 18.41 ENST00000330398.4
ENST00000568562.1
ENST00000569317.1
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
Uncharacterized protein
chr14_-_65438865 18.38 ENST00000267512.5
RAB15, member RAS oncogene family
chr20_+_10199468 18.33 ENST00000254976.2
ENST00000304886.2
synaptosomal-associated protein, 25kDa
chr13_+_98086445 18.32 ENST00000245304.4
RAP2A, member of RAS oncogene family
chr1_-_241520385 18.31 ENST00000366564.1
regulator of G-protein signaling 7
chr17_+_40118759 18.10 ENST00000393892.3
2',3'-cyclic nucleotide 3' phosphodiesterase
chr1_+_171810606 18.00 ENST00000358155.4
ENST00000367733.2
ENST00000355305.5
ENST00000367731.1
dynamin 3
chr13_-_36705425 17.96 ENST00000255448.4
ENST00000360631.3
ENST00000379892.4
doublecortin-like kinase 1
chr1_-_32229523 17.95 ENST00000398547.1
ENST00000373655.2
ENST00000373658.3
ENST00000257070.4
brain-specific angiogenesis inhibitor 2
chr16_+_85061367 17.92 ENST00000538274.1
ENST00000258180.3
KIAA0513
chr7_-_44365020 17.89 ENST00000395747.2
ENST00000347193.4
ENST00000346990.4
ENST00000258682.6
ENST00000353625.4
ENST00000421607.1
ENST00000424197.1
ENST00000502837.2
ENST00000350811.3
ENST00000395749.2
calcium/calmodulin-dependent protein kinase II beta
chr8_+_104152922 17.85 ENST00000309982.5
ENST00000438105.2
ENST00000297574.6
brain and acute leukemia, cytoplasmic
chr4_-_102267953 17.83 ENST00000523694.2
ENST00000507176.1
protein phosphatase 3, catalytic subunit, alpha isozyme
chr22_-_38851205 17.74 ENST00000303592.3
potassium inwardly-rectifying channel, subfamily J, member 4
chr17_-_80656528 17.70 ENST00000538809.2
ENST00000269347.6
ENST00000571995.1
RAB40B, member RAS oncogene family
chr16_+_56623433 17.68 ENST00000570176.1
metallothionein 3
chr3_+_11034403 17.65 ENST00000287766.4
ENST00000425938.1
solute carrier family 6 (neurotransmitter transporter), member 1
chr4_+_2845547 17.64 ENST00000264758.7
ENST00000446856.1
ENST00000398125.1
adducin 1 (alpha)
chr7_-_994302 17.59 ENST00000265846.5
ArfGAP with dual PH domains 1
chr20_+_57466461 17.50 ENST00000306090.10
GNAS complex locus
chr7_-_766879 17.43 ENST00000537384.1
ENST00000417852.1
protein kinase, cAMP-dependent, regulatory, type I, beta
chr4_-_102268628 17.41 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
protein phosphatase 3, catalytic subunit, alpha isozyme
chr17_-_79139817 17.35 ENST00000326724.4
apoptosis-associated tyrosine kinase
chr17_-_8066250 17.33 ENST00000488857.1
ENST00000481878.1
ENST00000316509.6
ENST00000498285.1
vesicle-associated membrane protein 2 (synaptobrevin 2)
Uncharacterized protein
chr19_+_36359341 17.31 ENST00000221891.4
amyloid beta (A4) precursor-like protein 1
chr4_-_17513851 17.30 ENST00000281243.5
quinoid dihydropteridine reductase
chr1_-_226924980 17.27 ENST00000272117.3
inositol-trisphosphate 3-kinase B
chr14_-_21493649 17.23 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG family member 2
chr9_+_17579084 17.17 ENST00000380607.4
SH3-domain GRB2-like 2
chr12_-_112819896 17.03 ENST00000377560.5
ENST00000430131.2
ENST00000550722.1
ENST00000550724.1
HECT domain containing E3 ubiquitin protein ligase 4
chr19_+_54926621 16.98 ENST00000376530.3
ENST00000445095.1
ENST00000391739.3
ENST00000376531.3
tweety family member 1
chr5_-_132112907 16.97 ENST00000458488.2
septin 8
chr1_-_230561475 16.94 ENST00000391860.1
piggyBac transposable element derived 5
chr20_+_57466357 16.79 ENST00000371095.3
ENST00000371085.3
ENST00000354359.7
ENST00000265620.7
GNAS complex locus
chr5_-_11904152 16.66 ENST00000304623.8
ENST00000458100.2
catenin (cadherin-associated protein), delta 2
chr20_+_44035200 16.65 ENST00000372717.1
ENST00000360981.4
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr9_+_131314859 16.63 ENST00000358161.5
ENST00000372731.4
ENST00000372739.3
spectrin, alpha, non-erythrocytic 1
chr11_+_121322832 16.62 ENST00000260197.7
sortilin-related receptor, L(DLR class) A repeats containing
chr9_+_129089088 16.61 ENST00000361171.3
ENST00000545391.1
multivesicular body subunit 12B
chr20_+_34742650 16.60 ENST00000373945.1
ENST00000338074.2
erythrocyte membrane protein band 4.1-like 1
chr5_-_132112921 16.56 ENST00000378721.4
ENST00000378701.1
septin 8
chr14_-_103987679 16.54 ENST00000553610.1
creatine kinase, brain
chrX_-_92928557 16.53 ENST00000373079.3
ENST00000475430.2
nucleosome assembly protein 1-like 3
chr14_+_105781048 16.41 ENST00000458164.2
ENST00000447393.1
phosphofurin acidic cluster sorting protein 2
chr14_+_100150622 16.41 ENST00000261835.3
cytochrome P450, family 46, subfamily A, polypeptide 1
chr7_+_153749732 16.38 ENST00000377770.3
dipeptidyl-peptidase 6
chr14_-_93581615 16.36 ENST00000555553.1
ENST00000555495.1
ENST00000554999.1
inositol-tetrakisphosphate 1-kinase
chr2_+_10442993 16.30 ENST00000423674.1
ENST00000307845.3
hippocalcin-like 1
chr2_-_242447962 16.27 ENST00000405883.3
serine/threonine kinase 25
chr8_-_80680078 16.21 ENST00000337919.5
ENST00000354724.3
hes-related family bHLH transcription factor with YRPW motif 1
chr5_-_11904100 16.19 ENST00000359640.2
catenin (cadherin-associated protein), delta 2
chr20_+_43514320 16.18 ENST00000372839.3
ENST00000428262.1
ENST00000445830.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
chr5_-_179499108 16.16 ENST00000521389.1
ring finger protein 130
chr8_+_26435359 16.02 ENST00000311151.5
dihydropyrimidinase-like 2
chr19_-_3700388 15.99 ENST00000589578.1
ENST00000537021.1
ENST00000539785.1
ENST00000335312.3
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
chr9_-_139922631 15.95 ENST00000341511.6
ATP-binding cassette, sub-family A (ABC1), member 2
chr9_-_111929560 15.93 ENST00000561981.2
ferric-chelate reductase 1-like
chr14_-_93651186 15.92 ENST00000556883.1
ENST00000298894.4
modulator of apoptosis 1
chr14_+_104029278 15.87 ENST00000472726.2
ENST00000409074.2
ENST00000440963.1
ENST00000556253.2
ENST00000247618.4
Kinesin light chain 1
apoptogenic 1, mitochondrial
chr11_-_65686496 15.86 ENST00000449692.3
chromosome 11 open reading frame 68
chrX_-_13956497 15.83 ENST00000398361.3
glycoprotein M6B
chr1_-_11714700 15.78 ENST00000354287.4
F-box protein 2
chr18_-_74844713 15.74 ENST00000397860.3
myelin basic protein
chr2_+_236402669 15.73 ENST00000409457.1
ENST00000336665.5
ENST00000304032.8
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr3_-_183543301 15.73 ENST00000318631.3
ENST00000431348.1
MAP6 domain containing 1
chr19_-_1885432 15.66 ENST00000250974.9
abhydrolase domain containing 17A
chr1_-_17338267 15.65 ENST00000326735.8
ATPase type 13A2
chr11_-_119293872 15.63 ENST00000524970.1
Thy-1 cell surface antigen
chr11_-_78128811 15.61 ENST00000530915.1
ENST00000361507.4
GRB2-associated binding protein 2
chr16_+_14165160 15.57 ENST00000574998.1
ENST00000571589.1
ENST00000574045.1
MKL/myocardin-like 2
chr16_+_23847339 15.44 ENST00000303531.7
protein kinase C, beta
chr2_+_231729615 15.43 ENST00000326427.6
ENST00000335005.6
ENST00000326407.6
integral membrane protein 2C
chr7_-_73133959 15.39 ENST00000395155.3
ENST00000395154.3
ENST00000222812.3
ENST00000395156.3
syntaxin 1A (brain)
chr11_-_65686586 15.25 ENST00000438576.2
chromosome 11 open reading frame 68
chr11_+_129939811 15.25 ENST00000345598.5
ENST00000338167.5
amyloid beta (A4) precursor-like protein 2
chr10_+_11207438 15.22 ENST00000609692.1
ENST00000354897.3
CUGBP, Elav-like family member 2
chr9_-_131790550 15.21 ENST00000372554.4
ENST00000372564.3
SH3-domain GRB2-like endophilin B2
chr1_-_85930823 15.16 ENST00000284031.8
ENST00000539042.1
dimethylarginine dimethylaminohydrolase 1
chr22_-_39151947 15.14 ENST00000216064.4
Sad1 and UNC84 domain containing 2
chr11_-_125366089 15.12 ENST00000366139.3
ENST00000278919.3
fasciculation and elongation protein zeta 1 (zygin I)
chr13_+_42031679 15.05 ENST00000379359.3
regulator of cell cycle
chr14_+_104095514 15.02 ENST00000348520.6
ENST00000380038.3
ENST00000389744.4
ENST00000557575.1
ENST00000553286.1
ENST00000347839.6
ENST00000555836.1
ENST00000334553.6
ENST00000246489.7
ENST00000557450.1
ENST00000452929.2
ENST00000554280.1
ENST00000445352.4
kinesin light chain 1
chr16_+_2564254 15.00 ENST00000565223.1
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr7_-_143059780 14.91 ENST00000409578.1
ENST00000409346.1
family with sequence similarity 131, member B
chr2_-_242447983 14.85 ENST00000426941.1
ENST00000405585.1
ENST00000420551.1
ENST00000535007.1
ENST00000429279.1
ENST00000442307.1
ENST00000403346.3
ENST00000316586.4
serine/threonine kinase 25
chr6_-_84418860 14.82 ENST00000521743.1
synaptosomal-associated protein, 91kDa
chr9_-_101471479 14.77 ENST00000259455.2
gamma-aminobutyric acid (GABA) B receptor, 2
chr9_-_131790464 14.76 ENST00000417224.1
ENST00000416629.1
ENST00000372559.1
SH3-domain GRB2-like endophilin B2
chr3_-_18466787 14.76 ENST00000338745.6
ENST00000450898.1
SATB homeobox 1
chr6_-_84419101 14.74 ENST00000520302.1
ENST00000520213.1
ENST00000439399.2
ENST00000428679.2
ENST00000437520.1
synaptosomal-associated protein, 91kDa
chr16_-_66785497 14.70 ENST00000440564.2
ENST00000379482.2
ENST00000443351.2
ENST00000566150.1
dynein, cytoplasmic 1, light intermediate chain 2
chr19_+_54926601 14.65 ENST00000301194.4
tweety family member 1
chr11_+_129939779 14.63 ENST00000533195.1
ENST00000533713.1
ENST00000528499.1
ENST00000539648.1
ENST00000263574.5
amyloid beta (A4) precursor-like protein 2
chr16_-_57318566 14.60 ENST00000569059.1
ENST00000219207.5
plasmolipin
chr20_+_11871371 14.59 ENST00000254977.3
BTB (POZ) domain containing 3
chr8_+_86376081 14.58 ENST00000285379.5
carbonic anhydrase II

Network of associatons between targets according to the STRING database.

First level regulatory network of SP4_PML

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
18.7 56.1 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
17.1 68.4 GO:0060313 negative regulation of blood vessel remodeling(GO:0060313)
16.8 67.0 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
12.1 36.2 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
11.0 131.5 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
10.7 32.2 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
10.5 31.4 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
10.3 51.6 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
10.1 30.2 GO:1905166 negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
9.9 29.8 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
9.7 29.0 GO:0009183 purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
9.0 27.0 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
8.8 26.5 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
8.1 24.3 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
8.1 32.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
7.9 71.5 GO:0003190 atrioventricular valve formation(GO:0003190)
7.8 23.5 GO:0097212 lysosomal membrane organization(GO:0097212)
7.7 23.0 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
7.7 61.4 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
7.5 29.9 GO:0071492 cellular response to UV-A(GO:0071492)
7.3 21.8 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
7.2 28.9 GO:0006542 glutamine biosynthetic process(GO:0006542)
7.1 35.3 GO:2001074 regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
7.0 35.1 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
7.0 7.0 GO:1902667 regulation of axon guidance(GO:1902667)
6.8 47.7 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
6.7 53.7 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
6.5 26.1 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
6.4 32.0 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
6.3 19.0 GO:0033693 neurofilament bundle assembly(GO:0033693)
6.2 6.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
6.1 36.6 GO:0090170 regulation of Golgi inheritance(GO:0090170)
6.0 18.0 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
5.9 17.8 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
5.9 47.1 GO:0032482 Rab protein signal transduction(GO:0032482)
5.9 41.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
5.9 23.5 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
5.9 76.1 GO:2001135 regulation of endocytic recycling(GO:2001135)
5.8 17.5 GO:1903028 positive regulation of opsonization(GO:1903028)
5.8 28.8 GO:0061107 seminal vesicle development(GO:0061107)
5.7 22.7 GO:0001757 somite specification(GO:0001757)
5.7 34.0 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
5.6 16.9 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
5.5 82.3 GO:0090168 Golgi reassembly(GO:0090168)
5.5 43.7 GO:0060075 regulation of resting membrane potential(GO:0060075)
5.4 21.5 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
5.3 47.9 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
5.3 53.2 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
5.3 15.9 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
5.2 26.2 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
4.9 14.8 GO:0035610 protein side chain deglutamylation(GO:0035610)
4.9 29.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
4.8 28.8 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
4.8 14.3 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
4.7 18.7 GO:1904978 regulation of endosome organization(GO:1904978)
4.7 14.0 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
4.6 4.6 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
4.6 73.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
4.6 13.8 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
4.6 18.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
4.6 36.4 GO:0008090 retrograde axonal transport(GO:0008090)
4.5 22.3 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
4.5 13.4 GO:0042137 sequestering of neurotransmitter(GO:0042137)
4.4 13.3 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
4.4 26.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
4.3 34.6 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
4.2 12.6 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
4.2 29.5 GO:0016191 synaptic vesicle uncoating(GO:0016191)
4.2 16.8 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
4.2 12.6 GO:0042938 dipeptide transport(GO:0042938)
4.1 20.6 GO:0035900 response to isolation stress(GO:0035900)
4.1 16.5 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
4.1 40.9 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
4.0 16.1 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
4.0 28.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
4.0 12.0 GO:1904799 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
4.0 47.9 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
3.9 39.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
3.9 11.7 GO:0032594 protein transport within lipid bilayer(GO:0032594) protein transport into membrane raft(GO:0032596)
3.9 39.0 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
3.9 11.7 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
3.8 11.5 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
3.8 15.1 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
3.8 11.3 GO:0072709 cellular response to sorbitol(GO:0072709)
3.8 18.8 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
3.8 11.3 GO:1904398 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) positive regulation of neuromuscular junction development(GO:1904398)
3.7 3.7 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
3.7 3.7 GO:0070142 synaptic vesicle budding(GO:0070142)
3.7 11.1 GO:0019417 sulfur oxidation(GO:0019417)
3.7 70.0 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
3.7 25.7 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
3.6 43.7 GO:0070050 neuron cellular homeostasis(GO:0070050)
3.6 29.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
3.6 14.5 GO:0097338 response to clozapine(GO:0097338)
3.6 25.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
3.6 14.3 GO:0021564 vagus nerve development(GO:0021564)
3.5 31.9 GO:0007042 lysosomal lumen acidification(GO:0007042)
3.5 7.1 GO:1901628 positive regulation of postsynaptic membrane organization(GO:1901628)
3.5 27.8 GO:2001016 positive regulation of skeletal muscle cell differentiation(GO:2001016)
3.5 45.1 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
3.4 6.9 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
3.4 17.2 GO:0016476 regulation of embryonic cell shape(GO:0016476)
3.4 24.0 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
3.4 54.6 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
3.4 16.8 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
3.3 96.9 GO:0048268 clathrin coat assembly(GO:0048268)
3.3 16.6 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
3.3 3.3 GO:1903423 positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423)
3.3 9.9 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
3.3 195.6 GO:0021762 substantia nigra development(GO:0021762)
3.3 16.3 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
3.3 19.5 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
3.2 9.7 GO:0060137 maternal process involved in parturition(GO:0060137)
3.2 9.7 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
3.2 12.6 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
3.1 6.2 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
3.1 15.4 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
3.0 24.4 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
3.0 9.1 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
3.0 15.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
3.0 24.0 GO:0097091 synaptic vesicle clustering(GO:0097091)
3.0 9.0 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
3.0 11.9 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
3.0 5.9 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
2.9 61.5 GO:0007035 vacuolar acidification(GO:0007035)
2.9 8.8 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
2.9 14.6 GO:0009608 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
2.9 43.6 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
2.9 14.4 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
2.8 11.4 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
2.8 11.3 GO:0046108 uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
2.8 8.4 GO:0032474 otolith morphogenesis(GO:0032474)
2.8 11.1 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
2.8 5.5 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
2.8 5.5 GO:0033602 negative regulation of dopamine secretion(GO:0033602)
2.8 8.3 GO:0001928 regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
2.7 8.1 GO:0090034 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
2.7 23.9 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
2.7 21.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
2.7 8.0 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
2.6 7.9 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
2.6 7.9 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
2.6 2.6 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
2.6 10.5 GO:0072660 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
2.6 10.5 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
2.6 15.7 GO:0032252 secretory granule localization(GO:0032252)
2.6 20.9 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
2.6 5.2 GO:1903012 positive regulation of bone development(GO:1903012) positive regulation of osteoclast development(GO:2001206)
2.6 7.8 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
2.6 5.2 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
2.6 38.4 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
2.6 2.6 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
2.6 20.4 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
2.6 7.7 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
2.5 22.9 GO:0033227 dsRNA transport(GO:0033227)
2.5 10.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
2.5 85.0 GO:0008045 motor neuron axon guidance(GO:0008045)
2.5 12.4 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
2.4 9.8 GO:0048102 autophagic cell death(GO:0048102)
2.4 14.6 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
2.4 51.0 GO:0032011 ARF protein signal transduction(GO:0032011)
2.4 7.3 GO:0060024 rhythmic synaptic transmission(GO:0060024)
2.4 31.4 GO:0046325 negative regulation of glucose import(GO:0046325)
2.4 9.6 GO:0003219 cardiac right ventricle formation(GO:0003219)
2.4 2.4 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
2.4 7.2 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
2.4 2.4 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
2.4 2.4 GO:0007113 endomitotic cell cycle(GO:0007113)
2.4 7.1 GO:1990834 response to odorant(GO:1990834)
2.4 4.7 GO:0007412 axon target recognition(GO:0007412)
2.3 4.7 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
2.3 16.4 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
2.3 11.7 GO:1990504 dense core granule exocytosis(GO:1990504)
2.3 55.8 GO:0046339 diacylglycerol metabolic process(GO:0046339)
2.3 9.3 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
2.3 4.6 GO:0009438 methylglyoxal metabolic process(GO:0009438)
2.3 47.8 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
2.3 4.5 GO:1902576 negative regulation of nuclear cell cycle DNA replication(GO:1902576)
2.3 11.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
2.3 6.8 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
2.3 18.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
2.2 6.7 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
2.2 24.7 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
2.2 6.7 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
2.2 8.9 GO:0046502 uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
2.2 8.9 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
2.2 2.2 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
2.2 17.7 GO:0006013 mannose metabolic process(GO:0006013)
2.2 6.6 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
2.2 6.6 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
2.2 10.9 GO:0030070 insulin processing(GO:0030070)
2.2 13.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
2.2 19.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
2.2 15.1 GO:0030913 paranodal junction assembly(GO:0030913)
2.2 4.3 GO:1902473 regulation of protein localization to synapse(GO:1902473)
2.1 6.4 GO:0060437 lung growth(GO:0060437)
2.1 6.4 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
2.1 8.5 GO:1902075 cellular response to salt(GO:1902075)
2.1 23.3 GO:2000210 positive regulation of anoikis(GO:2000210)
2.1 10.4 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
2.1 10.4 GO:0035063 nuclear speck organization(GO:0035063)
2.1 4.2 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664)
2.1 14.5 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
2.1 12.4 GO:0046958 nonassociative learning(GO:0046958)
2.1 4.1 GO:0021779 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
2.0 24.6 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
2.0 36.8 GO:0019371 cyclooxygenase pathway(GO:0019371)
2.0 18.4 GO:0038007 netrin-activated signaling pathway(GO:0038007)
2.0 12.2 GO:0046485 ether lipid metabolic process(GO:0046485)
2.0 2.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
2.0 2.0 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
2.0 2.0 GO:0060221 retinal rod cell differentiation(GO:0060221)
2.0 33.3 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
1.9 3.9 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
1.9 13.6 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
1.9 33.0 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
1.9 7.8 GO:0015808 L-alanine transport(GO:0015808)
1.9 7.7 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
1.9 34.7 GO:0034389 lipid particle organization(GO:0034389)
1.9 34.6 GO:0050812 regulation of acyl-CoA biosynthetic process(GO:0050812)
1.9 15.4 GO:0061314 Notch signaling involved in heart development(GO:0061314)
1.9 23.0 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
1.9 1.9 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
1.9 9.6 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
1.9 7.6 GO:0070375 ERK5 cascade(GO:0070375)
1.9 11.3 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
1.9 3.8 GO:2000574 regulation of microtubule motor activity(GO:2000574)
1.9 16.9 GO:0032286 central nervous system myelin maintenance(GO:0032286)
1.9 15.0 GO:0001661 conditioned taste aversion(GO:0001661)
1.9 1.9 GO:1990441 negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
1.9 7.4 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
1.9 29.7 GO:0018298 protein-chromophore linkage(GO:0018298)
1.8 18.4 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
1.8 12.8 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
1.8 85.8 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
1.8 9.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
1.8 5.5 GO:0042823 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
1.8 5.5 GO:2000521 negative regulation of immunological synapse formation(GO:2000521)
1.8 5.4 GO:1990108 protein linear deubiquitination(GO:1990108)
1.8 14.2 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
1.8 1.8 GO:0033127 regulation of histone phosphorylation(GO:0033127)
1.8 5.3 GO:0060615 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
1.8 1.8 GO:0010265 SCF complex assembly(GO:0010265)
1.8 5.3 GO:0071409 cellular response to cycloheximide(GO:0071409)
1.7 14.0 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.7 1.7 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
1.7 7.0 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
1.7 17.2 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
1.7 6.8 GO:1903416 response to glycoside(GO:1903416)
1.7 6.8 GO:0006382 adenosine to inosine editing(GO:0006382)
1.7 16.9 GO:0002091 negative regulation of receptor internalization(GO:0002091)
1.7 8.4 GO:1990034 calcium ion export from cell(GO:1990034)
1.7 1.7 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
1.7 3.3 GO:0046836 glycolipid transport(GO:0046836)
1.7 1.7 GO:0042158 protein lipidation(GO:0006497) lipoprotein biosynthetic process(GO:0042158)
1.7 3.3 GO:1904815 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
1.6 8.2 GO:0021978 telencephalon regionalization(GO:0021978)
1.6 3.3 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
1.6 4.8 GO:0043983 histone H4-K12 acetylation(GO:0043983)
1.6 6.4 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
1.6 9.6 GO:0036010 protein localization to endosome(GO:0036010)
1.6 9.6 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
1.6 9.5 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
1.6 7.9 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
1.6 39.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
1.6 3.1 GO:1902047 polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267)
1.6 21.8 GO:0019372 lipoxygenase pathway(GO:0019372)
1.6 10.9 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
1.6 43.4 GO:0032456 endocytic recycling(GO:0032456)
1.5 12.4 GO:0007258 JUN phosphorylation(GO:0007258)
1.5 10.7 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
1.5 1.5 GO:0051451 myoblast migration(GO:0051451)
1.5 6.1 GO:0014040 positive regulation of Schwann cell differentiation(GO:0014040)
1.5 7.6 GO:0035617 stress granule disassembly(GO:0035617)
1.5 1.5 GO:0033564 anterior/posterior axon guidance(GO:0033564)
1.5 1.5 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
1.5 3.0 GO:0045925 positive regulation of female receptivity(GO:0045925)
1.5 9.0 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
1.5 4.5 GO:0021592 fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
1.5 22.5 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
1.5 25.2 GO:0090383 phagosome acidification(GO:0090383)
1.5 2.9 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
1.5 1.5 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
1.5 8.8 GO:0090382 phagosome maturation(GO:0090382)
1.5 89.2 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
1.5 26.2 GO:0070977 bone maturation(GO:0070977)
1.5 11.6 GO:0072592 oxygen metabolic process(GO:0072592)
1.4 20.2 GO:0060004 reflex(GO:0060004)
1.4 10.0 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
1.4 12.8 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
1.4 7.1 GO:1901909 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
1.4 15.6 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
1.4 11.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
1.4 8.5 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
1.4 96.8 GO:0035773 insulin secretion involved in cellular response to glucose stimulus(GO:0035773)
1.4 9.8 GO:0070294 renal sodium ion absorption(GO:0070294)
1.4 15.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)
1.4 4.1 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
1.4 16.5 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
1.4 2.7 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
1.4 2.7 GO:0090527 actin filament reorganization(GO:0090527)
1.4 54.3 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
1.4 14.9 GO:0018345 protein palmitoylation(GO:0018345)
1.4 9.5 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
1.4 6.8 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
1.4 5.4 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
1.3 5.4 GO:0016322 neuron remodeling(GO:0016322)
1.3 5.4 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
1.3 30.8 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
1.3 51.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
1.3 1.3 GO:0031112 positive regulation of microtubule polymerization or depolymerization(GO:0031112)
1.3 4.0 GO:1900063 regulation of peroxisome organization(GO:1900063)
1.3 10.5 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
1.3 6.5 GO:0003322 pancreatic A cell development(GO:0003322)
1.3 3.9 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
1.3 9.1 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
1.3 9.1 GO:0033578 protein glycosylation in Golgi(GO:0033578)
1.3 3.9 GO:0051697 protein delipidation(GO:0051697)
1.3 46.7 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
1.3 2.6 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
1.3 5.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
1.3 5.2 GO:0019401 alditol biosynthetic process(GO:0019401)
1.3 1.3 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
1.3 2.6 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
1.3 14.0 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
1.3 3.8 GO:0070842 aggresome assembly(GO:0070842)
1.3 2.5 GO:1904251 regulation of bile acid metabolic process(GO:1904251)
1.3 5.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
1.3 8.9 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
1.3 10.0 GO:0051601 exocyst localization(GO:0051601)
1.3 25.0 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
1.2 1.2 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
1.2 1.2 GO:1903116 positive regulation of actin filament-based movement(GO:1903116)
1.2 9.9 GO:0002911 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
1.2 18.6 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
1.2 5.0 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
1.2 7.4 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
1.2 3.7 GO:0032100 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
1.2 7.4 GO:0035709 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
1.2 2.4 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
1.2 4.8 GO:0030035 microspike assembly(GO:0030035)
1.2 4.8 GO:0051957 positive regulation of amino acid transport(GO:0051957)
1.2 1.2 GO:0043084 penile erection(GO:0043084)
1.2 45.8 GO:0006376 mRNA splice site selection(GO:0006376)
1.2 1.2 GO:0006553 lysine metabolic process(GO:0006553)
1.2 22.8 GO:0006622 protein targeting to lysosome(GO:0006622)
1.2 2.4 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
1.2 8.2 GO:1900077 negative regulation of cellular response to insulin stimulus(GO:1900077)
1.2 16.5 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
1.2 3.5 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
1.2 3.5 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
1.2 1.2 GO:0051541 elastin metabolic process(GO:0051541)
1.2 1.2 GO:0043117 positive regulation of vascular permeability(GO:0043117)
1.2 40.6 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
1.2 1.2 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
1.2 6.9 GO:0061462 protein localization to lysosome(GO:0061462)
1.2 17.3 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
1.2 15.0 GO:0071625 vocalization behavior(GO:0071625)
1.2 1.2 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
1.2 1.2 GO:0044091 membrane biogenesis(GO:0044091)
1.1 4.6 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
1.1 5.7 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
1.1 3.4 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
1.1 22.8 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
1.1 6.8 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
1.1 19.2 GO:0007021 tubulin complex assembly(GO:0007021)
1.1 6.8 GO:0048243 norepinephrine secretion(GO:0048243)
1.1 14.6 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
1.1 9.0 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
1.1 21.3 GO:0051764 actin crosslink formation(GO:0051764)
1.1 1.1 GO:0071257 cellular response to electrical stimulus(GO:0071257)
1.1 1.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
1.1 4.5 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
1.1 2.2 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
1.1 6.6 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
1.1 6.6 GO:0001705 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
1.1 13.2 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
1.1 7.7 GO:0045161 neuronal ion channel clustering(GO:0045161)
1.1 5.5 GO:0070560 protein secretion by platelet(GO:0070560)
1.1 6.5 GO:0097062 dendritic spine maintenance(GO:0097062)
1.1 3.3 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
1.1 6.5 GO:0034214 protein hexamerization(GO:0034214)
1.1 4.3 GO:0032534 regulation of microvillus assembly(GO:0032534)
1.1 4.3 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
1.1 11.8 GO:2001224 positive regulation of neuron migration(GO:2001224)
1.1 2.1 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
1.1 9.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
1.1 2.1 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
1.1 21.3 GO:1903432 regulation of TORC1 signaling(GO:1903432)
1.1 5.3 GO:0002036 regulation of L-glutamate transport(GO:0002036)
1.1 5.3 GO:0090160 Golgi to lysosome transport(GO:0090160)
1.1 2.1 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
1.1 2.1 GO:0035419 activation of MAPK activity involved in innate immune response(GO:0035419)
1.0 7.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
1.0 3.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
1.0 5.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
1.0 3.1 GO:1904579 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) response to hypobaric hypoxia(GO:1990910)
1.0 20.6 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
1.0 3.1 GO:0034182 regulation of maintenance of sister chromatid cohesion(GO:0034091) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182)
1.0 1.0 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
1.0 17.3 GO:0044803 multi-organism membrane organization(GO:0044803)
1.0 5.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
1.0 6.1 GO:1901550 regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
1.0 22.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
1.0 33.4 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
1.0 4.0 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
1.0 3.0 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
1.0 98.1 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
1.0 12.9 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
1.0 5.0 GO:0019640 glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159)
1.0 22.8 GO:0014003 oligodendrocyte development(GO:0014003)
1.0 7.9 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
1.0 3.9 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
1.0 3.9 GO:0097320 membrane tubulation(GO:0097320)
1.0 2.0 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
1.0 1.0 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
1.0 36.8 GO:0046785 microtubule polymerization(GO:0046785)
1.0 2.9 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
1.0 3.9 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
1.0 7.7 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
1.0 1.0 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
1.0 1.0 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.9 5.7 GO:0005985 sucrose metabolic process(GO:0005985)
0.9 2.8 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.9 9.5 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.9 12.3 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.9 4.7 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.9 0.9 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.9 6.5 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.9 4.6 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.9 1.9 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.9 2.8 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.9 0.9 GO:0060352 cell adhesion molecule production(GO:0060352)
0.9 1.8 GO:0060454 positive regulation of gastric acid secretion(GO:0060454)
0.9 9.1 GO:0098930 anterograde axonal transport(GO:0008089) axonal transport(GO:0098930)
0.9 5.5 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.9 5.4 GO:0051012 microtubule sliding(GO:0051012)
0.9 41.6 GO:0046847 filopodium assembly(GO:0046847)
0.9 4.5 GO:0061668 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.9 0.9 GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.9 1.8 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.9 10.6 GO:0001881 receptor recycling(GO:0001881)
0.9 1.8 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
0.9 3.5 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.9 0.9 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.9 7.0 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.9 27.9 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.9 3.5 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.9 9.5 GO:0032438 melanosome organization(GO:0032438)
0.9 2.6 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.9 2.6 GO:0002880 chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880) negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.9 0.9 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.9 2.6 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.9 2.6 GO:0031657 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657)
0.8 1.7 GO:2000341 regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000341)
0.8 7.6 GO:0030091 protein repair(GO:0030091)
0.8 4.2 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.8 1.7 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.8 5.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.8 1.7 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.8 3.4 GO:0048388 endosomal lumen acidification(GO:0048388)
0.8 3.4 GO:0044375 regulation of peroxisome size(GO:0044375)
0.8 0.8 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.8 15.1 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.8 3.4 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.8 28.4 GO:0007041 lysosomal transport(GO:0007041)
0.8 36.5 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.8 21.5 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.8 2.5 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.8 1.6 GO:0042940 D-amino acid transport(GO:0042940)
0.8 5.7 GO:0042118 endothelial cell activation(GO:0042118)
0.8 1.6 GO:0097352 autophagosome maturation(GO:0097352)
0.8 7.3 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.8 0.8 GO:0090045 positive regulation of deacetylase activity(GO:0090045)
0.8 2.4 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.8 1.6 GO:0035524 proline transmembrane transport(GO:0035524)
0.8 5.6 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.8 7.2 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.8 0.8 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.8 2.4 GO:1904504 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.8 5.5 GO:0070459 prolactin secretion(GO:0070459)
0.8 0.8 GO:0009182 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182)
0.8 2.4 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.8 10.3 GO:0009068 aspartate family amino acid catabolic process(GO:0009068)
0.8 1.6 GO:0030242 pexophagy(GO:0030242)
0.8 0.8 GO:0098910 regulation of atrial cardiac muscle cell action potential(GO:0098910)
0.8 7.0 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.8 4.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.8 3.1 GO:0050715 positive regulation of cytokine secretion(GO:0050715)
0.8 0.8 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.8 4.6 GO:0007413 axonal fasciculation(GO:0007413)
0.8 1.5 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.8 9.1 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.8 7.6 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.8 3.0 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.8 1.5 GO:0038027 apolipoprotein A-I-mediated signaling pathway(GO:0038027)
0.8 3.8 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.8 45.1 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.7 7.5 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.7 6.6 GO:0006068 ethanol catabolic process(GO:0006068)
0.7 2.9 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.7 2.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.7 0.7 GO:1903909 regulation of receptor clustering(GO:1903909)
0.7 2.9 GO:0032053 ciliary basal body organization(GO:0032053)
0.7 7.2 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.7 5.0 GO:0030497 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.7 2.9 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.7 4.3 GO:0015853 adenine transport(GO:0015853)
0.7 3.6 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.7 5.0 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.7 1.4 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.7 2.8 GO:0030822 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.7 0.7 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
0.7 6.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.7 9.1 GO:0002021 response to dietary excess(GO:0002021)
0.7 1.4 GO:0060027 convergent extension involved in gastrulation(GO:0060027)
0.7 1.4 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.7 5.6 GO:0001778 plasma membrane repair(GO:0001778)
0.7 1.4 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.7 3.5 GO:1901093 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.7 25.5 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.7 4.1 GO:0032472 Golgi calcium ion homeostasis(GO:0032468) Golgi calcium ion transport(GO:0032472)
0.7 3.4 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.7 2.7 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.7 2.0 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.7 2.7 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.7 2.7 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.7 5.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.7 2.0 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.7 2.7 GO:0032415 regulation of sodium:proton antiporter activity(GO:0032415) positive regulation of sodium:proton antiporter activity(GO:0032417)
0.7 1.3 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.7 19.7 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.7 7.9 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.7 1.3 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.7 7.8 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.7 1.3 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.6 2.6 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.6 0.6 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.6 3.2 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512) cell migration involved in kidney development(GO:0035787) cell migration involved in metanephros development(GO:0035788) metanephric mesenchymal cell migration(GO:0035789) positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) negative regulation of phospholipid biosynthetic process(GO:0071072) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) regulation of metanephric mesenchymal cell migration(GO:2000589) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.6 1.9 GO:0042045 epithelial fluid transport(GO:0042045)
0.6 1.9 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.6 1.9 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.6 10.8 GO:0006198 cAMP catabolic process(GO:0006198)
0.6 3.8 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.6 7.5 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.6 3.1 GO:0046710 GDP metabolic process(GO:0046710)
0.6 21.1 GO:0035307 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.6 0.6 GO:1990502 dense core granule maturation(GO:1990502)
0.6 2.5 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.6 0.6 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.6 1.2 GO:0075136 response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572) response to host(GO:0075136)
0.6 1.8 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.6 6.7 GO:0015886 heme transport(GO:0015886)
0.6 2.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.6 1.2 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.6 2.4 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.6 0.6 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.6 3.0 GO:0051654 establishment of mitochondrion localization(GO:0051654)
0.6 1.8 GO:0036511 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.6 2.4 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.6 2.4 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.6 6.5 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.6 1.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.6 3.6 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.6 3.0 GO:1903393 positive regulation of adherens junction organization(GO:1903393)
0.6 1.2 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.6 2.4 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.6 0.6 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.6 10.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.6 3.5 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.6 1.2 GO:0001523 retinoid metabolic process(GO:0001523)
0.6 5.3 GO:0032264 IMP salvage(GO:0032264)
0.6 0.6 GO:2000467 regulation of glycogen (starch) synthase activity(GO:2000465) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.6 1.7 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.6 2.9 GO:0071440 regulation of histone H3-K14 acetylation(GO:0071440)
0.6 0.6 GO:0045404 interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.6 2.9 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.6 2.9 GO:1904181 positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.6 5.1 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.6 2.8 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.6 2.3 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.6 1.7 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.6 7.8 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.6 0.6 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.6 1.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.6 2.2 GO:0042412 taurine biosynthetic process(GO:0042412)
0.6 7.8 GO:0071294 cellular response to zinc ion(GO:0071294)
0.6 19.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.5 1.6 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367) regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.5 8.2 GO:0000338 protein deneddylation(GO:0000338)
0.5 3.2 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.5 1.1 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.5 3.2 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.5 1.6 GO:0002818 intracellular defense response(GO:0002818)
0.5 2.1 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.5 4.8 GO:0046689 response to mercury ion(GO:0046689)
0.5 1.1 GO:0006740 NADPH regeneration(GO:0006740)
0.5 1.1 GO:0016559 peroxisome fission(GO:0016559)
0.5 20.0 GO:0090102 cochlea development(GO:0090102)
0.5 0.5 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.5 1.6 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.5 0.5 GO:0031133 regulation of axon diameter(GO:0031133)
0.5 2.6 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.5 4.1 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.5 2.0 GO:0080009 mRNA methylation(GO:0080009)
0.5 6.1 GO:0034063 stress granule assembly(GO:0034063)
0.5 2.5 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.5 3.0 GO:0009650 UV protection(GO:0009650)
0.5 5.0 GO:0009249 protein lipoylation(GO:0009249)
0.5 2.5 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.5 5.0 GO:0060292 long term synaptic depression(GO:0060292)
0.5 30.8 GO:0048813 dendrite morphogenesis(GO:0048813)
0.5 0.5 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.5 5.9 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.5 12.4 GO:0051693 actin filament capping(GO:0051693)
0.5 3.5 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.5 1.0 GO:0051029 rRNA transport(GO:0051029)
0.5 10.3 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.5 1.5 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.5 7.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.5 1.0 GO:0046929 negative regulation of neurotransmitter secretion(GO:0046929)
0.5 0.5 GO:0006517 protein deglycosylation(GO:0006517)
0.5 4.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.5 5.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.5 23.1 GO:0015701 bicarbonate transport(GO:0015701)
0.5 1.0 GO:0051866 general adaptation syndrome(GO:0051866)
0.5 0.5 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.5 3.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.5 1.9 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.5 2.4 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.5 0.5 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.5 0.5 GO:0010935 macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935)
0.5 1.4 GO:0072178 nephric duct morphogenesis(GO:0072178)
0.5 4.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.5 13.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.5 0.5 GO:0015846 polyamine transport(GO:0015846)
0.5 0.9 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.5 2.3 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.5 4.1 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.5 0.5 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.5 5.9 GO:0071539 protein localization to centrosome(GO:0071539)
0.5 3.2 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.5 1.8 GO:0051126 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126)
0.5 16.7 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.4 0.9 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.4 2.7 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.4 3.6 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.4 4.5 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.4 4.0 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.4 1.3 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.4 2.7 GO:0070458 cellular detoxification of nitrogen compound(GO:0070458)
0.4 9.6 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.4 2.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.4 2.6 GO:0071763 nuclear membrane organization(GO:0071763)
0.4 3.0 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.4 0.4 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.4 7.0 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.4 8.7 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.4 0.9 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.4 0.4 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.4 0.4 GO:0019400 alditol metabolic process(GO:0019400)
0.4 0.4 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.4 1.3 GO:0042756 drinking behavior(GO:0042756)
0.4 0.8 GO:0070831 basement membrane assembly(GO:0070831)
0.4 0.4 GO:0060157 urinary bladder development(GO:0060157)
0.4 0.8 GO:0043486 histone exchange(GO:0043486)
0.4 5.9 GO:0016540 protein autoprocessing(GO:0016540)
0.4 2.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.4 1.2 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.4 4.1 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.4 1.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.4 1.2 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.4 0.4 GO:0006776 vitamin A metabolic process(GO:0006776)
0.4 3.2 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.4 0.8 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.4 0.4 GO:0071287 cellular response to manganese ion(GO:0071287)
0.4 2.0 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.4 7.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.4 2.8 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.4 0.4 GO:0021578 hindbrain maturation(GO:0021578) central nervous system maturation(GO:0021626)
0.4 0.4 GO:1900368 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
0.4 3.2 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.4 1.2 GO:0046463 triglyceride biosynthetic process(GO:0019432) neutral lipid biosynthetic process(GO:0046460) acylglycerol biosynthetic process(GO:0046463)
0.4 0.8 GO:0055099 detection of endogenous stimulus(GO:0009726) response to high density lipoprotein particle(GO:0055099)
0.4 1.6 GO:0016139 glycoside catabolic process(GO:0016139)
0.4 5.1 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.4 1.9 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.4 1.2 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.4 0.4 GO:0090212 regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.4 2.3 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.4 9.5 GO:0010107 potassium ion import(GO:0010107)
0.4 1.9 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.4 0.8 GO:0033081 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.4 2.6 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.4 3.0 GO:0033327 Leydig cell differentiation(GO:0033327)
0.4 3.0 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.4 2.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.4 1.9 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.4 0.4 GO:1902744 negative regulation of lamellipodium organization(GO:1902744)
0.4 1.1 GO:0008306 associative learning(GO:0008306)
0.4 3.0 GO:0048820 hair follicle maturation(GO:0048820)
0.4 0.4 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.4 1.4 GO:0030259 lipid glycosylation(GO:0030259)
0.4 10.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.4 1.1 GO:0043129 surfactant homeostasis(GO:0043129)
0.4 1.4 GO:0016198 axon choice point recognition(GO:0016198)
0.4 1.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.4 0.7 GO:0016572 histone phosphorylation(GO:0016572)
0.3 7.7 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.3 1.4 GO:0009414 response to water deprivation(GO:0009414)
0.3 1.4 GO:0050807 regulation of synapse organization(GO:0050807)
0.3 1.4 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.3 6.2 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.3 0.3 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.3 2.4 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.3 7.5 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.3 5.8 GO:0061157 mRNA destabilization(GO:0061157)
0.3 0.3 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.3 1.0 GO:0071344 diphosphate metabolic process(GO:0071344)
0.3 1.0 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.3 11.3 GO:0032006 regulation of TOR signaling(GO:0032006)
0.3 1.0 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.3 2.3 GO:0070995 NADPH oxidation(GO:0070995)
0.3 0.7 GO:0008063 Toll signaling pathway(GO:0008063)
0.3 0.3 GO:0051683 establishment of Golgi localization(GO:0051683)
0.3 1.6 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.3 1.0 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.3 0.7 GO:0006754 ATP biosynthetic process(GO:0006754)
0.3 0.3 GO:0009155 purine deoxyribonucleotide catabolic process(GO:0009155) dATP catabolic process(GO:0046061)
0.3 11.6 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.3 4.5 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.3 0.6 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.3 0.6 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) positive regulation of microtubule binding(GO:1904528)
0.3 3.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.3 0.6 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.3 0.9 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.3 2.2 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.3 6.8 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.3 0.3 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.3 0.6 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.3 0.6 GO:0051350 negative regulation of lyase activity(GO:0051350)
0.3 0.6 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.3 0.3 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.3 0.3 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.3 6.3 GO:0008542 visual learning(GO:0008542)
0.3 1.2 GO:0070982 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.3 1.2 GO:0046618 drug export(GO:0046618)
0.3 0.6 GO:0060042 retina morphogenesis in camera-type eye(GO:0060042)
0.3 0.3 GO:0044362 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.3 1.8 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.3 0.9 GO:1903599 positive regulation of mitophagy(GO:1903599)
0.3 0.6 GO:0032494 response to peptidoglycan(GO:0032494)
0.3 0.6 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.3 1.5 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.3 2.0 GO:0071569 protein ufmylation(GO:0071569)
0.3 0.3 GO:0032607 interferon-alpha production(GO:0032607)
0.3 1.4 GO:0006574 valine catabolic process(GO:0006574)
0.3 1.2 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.3 2.0 GO:0014820 tonic smooth muscle contraction(GO:0014820)
0.3 1.1 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.3 0.3 GO:0097484 dendrite extension(GO:0097484)
0.3 2.0 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.3 1.1 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.3 5.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.3 1.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.3 1.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.3 0.6 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.3 0.3 GO:0036090 cleavage furrow ingression(GO:0036090)
0.3 0.6 GO:0002384 hepatic immune response(GO:0002384)
0.3 0.3 GO:2000366 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.3 0.8 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.3 1.1 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.3 6.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.3 1.8 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.3 1.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.3 3.1 GO:0005513 detection of calcium ion(GO:0005513)
0.3 1.0 GO:0031269 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.3 9.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.3 2.6 GO:0035640 exploration behavior(GO:0035640)
0.3 0.8 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.3 3.8 GO:0044030 regulation of DNA methylation(GO:0044030)
0.3 0.5 GO:0009826 unidimensional cell growth(GO:0009826)
0.3 4.3 GO:0000045 autophagosome assembly(GO:0000045)
0.3 3.3 GO:0097178 ruffle assembly(GO:0097178)
0.3 0.3 GO:0035973 aggrephagy(GO:0035973)
0.3 1.0 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.3 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.3 0.5 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.3 0.5 GO:0061245 establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of bipolar cell polarity(GO:0061245)
0.3 0.5 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.2 2.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.2 1.2 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.2 0.7 GO:0002578 negative regulation of antigen processing and presentation(GO:0002578)
0.2 0.7 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.2 2.9 GO:0034776 response to histamine(GO:0034776)
0.2 1.0 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.2 2.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.2 1.0 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.2 0.2 GO:1905031 regulation of potassium ion export across plasma membrane(GO:1903764) regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905031)
0.2 0.5 GO:0007288 sperm axoneme assembly(GO:0007288)
0.2 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.2 12.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 4.4 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.2 6.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 10.6 GO:0030516 regulation of axon extension(GO:0030516)
0.2 2.3 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.2 5.5 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.2 0.9 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.2 5.9 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.2 0.2 GO:0043335 protein unfolding(GO:0043335)
0.2 3.8 GO:0014889 muscle atrophy(GO:0014889)
0.2 1.3 GO:0071318 cellular response to ATP(GO:0071318)
0.2 0.4 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.2 1.3 GO:0042426 choline catabolic process(GO:0042426)
0.2 4.1 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.2 0.4 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.2 0.2 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
0.2 2.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.2 9.3 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.2 2.1 GO:0070207 protein homotrimerization(GO:0070207)
0.2 1.4 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.2 0.4 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.2 0.4 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.2 1.8 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.2 0.8 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.2 1.0 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.2 2.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.2 0.2 GO:0090427 activation of meiosis(GO:0090427)
0.2 0.4 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.2 0.4 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.2 1.5 GO:0051924 regulation of calcium ion transport(GO:0051924)
0.2 11.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.2 0.6 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.2 0.8 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.2 1.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.2 0.6 GO:0006434 seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.2 0.4 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.2 0.9 GO:0051014 actin filament severing(GO:0051014)
0.2 0.6 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.2 0.7 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.2 1.1 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.2 0.9 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.2 0.9 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.2 0.2 GO:0060467 negative regulation of fertilization(GO:0060467)
0.2 2.4 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.2 0.9 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.2 3.5 GO:0050832 defense response to fungus(GO:0050832)
0.2 9.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 2.5 GO:0032418 lysosome localization(GO:0032418)
0.2 1.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.2 0.5 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.2 0.7 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.2 2.1 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.2 0.7 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.2 0.5 GO:0042360 vitamin E metabolic process(GO:0042360)
0.2 1.2 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.2 0.7 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2 0.2 GO:0046337 phosphatidylethanolamine metabolic process(GO:0046337)
0.2 3.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 0.8 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.2 1.1 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.2 0.3 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.2 0.2 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.2 0.5 GO:0010827 regulation of glucose transport(GO:0010827)
0.2 0.6 GO:0051969 regulation of transmission of nerve impulse(GO:0051969)
0.2 0.6 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 1.8 GO:1902803 regulation of synaptic vesicle transport(GO:1902803)
0.1 0.6 GO:0006600 creatine metabolic process(GO:0006600)
0.1 1.6 GO:1901071 glucosamine-containing compound metabolic process(GO:1901071)
0.1 2.8 GO:0010976 positive regulation of neuron projection development(GO:0010976)
0.1 0.3 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 0.7 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.4 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.4 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.1 0.9 GO:0042026 protein refolding(GO:0042026)
0.1 2.8 GO:0042417 dopamine metabolic process(GO:0042417)
0.1 0.6 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 0.3 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.1 0.9 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.1 2.6 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.1 0.3 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.1 0.8 GO:0090196 chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196)
0.1 0.6 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.1 0.7 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1 2.5 GO:0005980 glycogen catabolic process(GO:0005980)
0.1 0.1 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 2.3 GO:0010669 epithelial structure maintenance(GO:0010669)
0.1 2.2 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 0.5 GO:2001293 malonyl-CoA metabolic process(GO:2001293) malonyl-CoA biosynthetic process(GO:2001295)
0.1 0.9 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 1.2 GO:0006552 leucine catabolic process(GO:0006552)
0.1 37.9 GO:0043687 post-translational protein modification(GO:0043687)
0.1 0.4 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.8 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.1 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.3 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.1 0.1 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 0.3 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.1 0.4 GO:0070781 response to biotin(GO:0070781)
0.1 0.4 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.1 4.5 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.1 0.3 GO:0006788 heme oxidation(GO:0006788)
0.1 3.0 GO:0046323 glucose import(GO:0046323)
0.1 1.0 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.1 0.2 GO:2000553 positive regulation of T-helper 2 cell cytokine production(GO:2000553)
0.1 1.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.4 GO:0045957 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.1 2.2 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.1 1.8 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.1 GO:0030431 sleep(GO:0030431)
0.1 1.0 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 0.2 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.1 0.5 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.1 0.1 GO:0006983 ER overload response(GO:0006983)
0.1 1.2 GO:0044070 regulation of anion transport(GO:0044070)
0.1 2.6 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.1 0.2 GO:1901160 primary amino compound metabolic process(GO:1901160)
0.1 0.5 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.1 0.6 GO:0006265 DNA topological change(GO:0006265)
0.1 0.1 GO:0046850 regulation of bone remodeling(GO:0046850)
0.1 0.2 GO:0071105 response to interleukin-11(GO:0071105)
0.1 1.5 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 4.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 0.4 GO:0048749 compound eye development(GO:0048749)
0.1 0.1 GO:0048539 bone marrow development(GO:0048539)
0.1 0.1 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
0.1 0.3 GO:0045073 regulation of chemokine biosynthetic process(GO:0045073)
0.1 4.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 0.2 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 1.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.3 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.1 0.4 GO:0015705 iodide transport(GO:0015705)
0.1 0.4 GO:0007512 adult heart development(GO:0007512)
0.1 1.1 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 0.1 GO:2000667 positive regulation of interleukin-13 secretion(GO:2000667)
0.1 0.1 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.1 0.1 GO:0002265 astrocyte activation involved in immune response(GO:0002265)
0.1 0.1 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.1 0.4 GO:0010455 positive regulation of cell fate commitment(GO:0010455)
0.1 0.3 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.1 0.3 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.1 0.9 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.4 GO:0043382 regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382)
0.1 0.6 GO:0030837 negative regulation of actin filament polymerization(GO:0030837)
0.1 0.3 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
0.1 0.3 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 0.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.5 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.1 0.4 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.3 GO:0060697 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902) positive regulation of phospholipid catabolic process(GO:0060697)
0.1 0.3 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.7 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 0.6 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.1 0.3 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.1 33.6 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.1 0.7 GO:0003091 renal water homeostasis(GO:0003091)
0.1 0.2 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.1 0.4 GO:0015874 norepinephrine transport(GO:0015874)
0.1 1.2 GO:0097502 mannosylation(GO:0097502)
0.1 0.4 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.5 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 0.2 GO:0006566 threonine metabolic process(GO:0006566)
0.1 0.4 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.4 GO:0015827 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820) tryptophan transport(GO:0015827) leucine import(GO:0060356)
0.1 0.1 GO:0046984 regulation of hemoglobin biosynthetic process(GO:0046984)
0.1 0.9 GO:0097186 amelogenesis(GO:0097186)
0.1 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.1 0.2 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.1 2.9 GO:0046834 lipid phosphorylation(GO:0046834)
0.1 0.2 GO:0051039 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.1 0.1 GO:0001569 patterning of blood vessels(GO:0001569)
0.1 0.4 GO:0072718 response to cisplatin(GO:0072718)
0.1 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 0.4 GO:0035330 regulation of hippo signaling(GO:0035330)
0.1 0.1 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.1 0.1 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.1 0.2 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.1 0.1 GO:0002448 mast cell mediated immunity(GO:0002448)
0.1 0.1 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.1 0.2 GO:0009268 response to pH(GO:0009268)
0.1 0.6 GO:0007045 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)
0.1 0.2 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.1 0.2 GO:0030042 actin filament depolymerization(GO:0030042)
0.1 0.2 GO:0050779 RNA destabilization(GO:0050779)
0.1 0.2 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1 0.8 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 1.1 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 0.1 GO:0032095 regulation of response to food(GO:0032095)
0.1 0.2 GO:1901626 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075) regulation of postsynaptic membrane organization(GO:1901626)
0.1 0.1 GO:0046596 regulation of viral entry into host cell(GO:0046596)
0.1 0.1 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.1 0.2 GO:0097480 synaptic vesicle transport(GO:0048489) establishment of synaptic vesicle localization(GO:0097480)
0.1 1.1 GO:0042461 photoreceptor cell development(GO:0042461)
0.1 0.1 GO:0023058 adaptation of signaling pathway(GO:0023058)
0.1 0.7 GO:0051057 positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.1 0.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.6 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.8 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.2 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 4.8 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.0 GO:0051928 positive regulation of calcium ion transport(GO:0051928)
0.0 0.0 GO:0014719 skeletal muscle satellite cell activation(GO:0014719)
0.0 0.2 GO:0071351 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.0 0.3 GO:0046174 polyol catabolic process(GO:0046174)
0.0 0.0 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.3 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0 0.5 GO:0022900 electron transport chain(GO:0022900)
0.0 0.2 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.1 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.3 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.2 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.0 0.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.1 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.1 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.9 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.2 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.1 GO:0015747 urate transport(GO:0015747)
0.0 1.0 GO:0055074 calcium ion homeostasis(GO:0055074)
0.0 0.2 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.1 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.0 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.0 0.2 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.1 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.0 0.0 GO:0036100 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.0 0.1 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0048679 regulation of axon regeneration(GO:0048679)
0.0 0.1 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.0 0.1 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.1 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.1 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.0 0.0 GO:0045345 positive regulation of MHC class I biosynthetic process(GO:0045345)
0.0 0.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.1 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.0 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.0 0.0 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
14.7 58.6 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
12.7 38.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
11.7 81.9 GO:0033269 internode region of axon(GO:0033269)
8.6 42.8 GO:0098843 postsynaptic endocytic zone(GO:0098843)
8.2 32.9 GO:0031166 integral component of vacuolar membrane(GO:0031166)
7.3 21.9 GO:0019034 viral replication complex(GO:0019034)
7.1 42.4 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
6.6 59.1 GO:0005955 calcineurin complex(GO:0005955)
6.3 37.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
6.2 24.9 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
5.9 23.7 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
5.2 20.8 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
5.1 107.3 GO:0044295 axonal growth cone(GO:0044295)
4.9 34.6 GO:0044326 dendritic spine neck(GO:0044326)
4.7 14.2 GO:0060053 neurofilament cytoskeleton(GO:0060053)
4.7 18.8 GO:0042995 cell projection(GO:0042995)
4.6 4.6 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
4.6 13.9 GO:0016938 kinesin I complex(GO:0016938)
4.6 64.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
4.5 18.2 GO:0031673 H zone(GO:0031673)
4.4 13.3 GO:0043291 RAVE complex(GO:0043291)
4.2 84.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
4.2 25.1 GO:0044327 dendritic spine head(GO:0044327)
4.1 20.5 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
4.0 24.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
3.9 66.4 GO:0097386 glial cell projection(GO:0097386)
3.8 11.5 GO:0072534 perineuronal net(GO:0072534)
3.8 30.4 GO:0098845 postsynaptic endosome(GO:0098845)
3.7 47.9 GO:0097433 dense body(GO:0097433)
3.7 11.0 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
3.5 78.0 GO:0032591 dendritic spine membrane(GO:0032591)
3.5 45.9 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
3.4 24.1 GO:0000813 ESCRT I complex(GO:0000813)
3.4 44.5 GO:0097470 ribbon synapse(GO:0097470)
3.4 40.9 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
3.4 33.8 GO:0045180 basal cortex(GO:0045180)
3.4 26.9 GO:0045179 apical cortex(GO:0045179)
3.4 6.7 GO:0014802 terminal cisterna(GO:0014802)
3.3 9.9 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
3.2 15.9 GO:0045298 tubulin complex(GO:0045298)
3.2 170.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
3.1 25.1 GO:0097208 alveolar lamellar body(GO:0097208)
3.1 21.8 GO:0002178 palmitoyltransferase complex(GO:0002178)
3.0 48.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
3.0 75.2 GO:0031143 pseudopodium(GO:0031143)
3.0 35.7 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
3.0 23.6 GO:0035976 AP1 complex(GO:0035976)
2.9 242.0 GO:0043195 terminal bouton(GO:0043195)
2.8 27.8 GO:0097427 microtubule bundle(GO:0097427)
2.8 41.3 GO:0043194 axon initial segment(GO:0043194)
2.7 40.8 GO:0008290 F-actin capping protein complex(GO:0008290)
2.7 10.7 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
2.6 26.0 GO:0005875 microtubule associated complex(GO:0005875)
2.5 33.0 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
2.5 35.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
2.5 22.2 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
2.4 12.2 GO:0042583 chromaffin granule(GO:0042583)
2.4 9.7 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
2.4 72.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
2.4 7.1 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
2.3 16.4 GO:0036021 endolysosome lumen(GO:0036021)
2.2 100.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
2.2 6.6 GO:0000806 Y chromosome(GO:0000806)
2.2 36.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
2.2 28.1 GO:0097418 neurofibrillary tangle(GO:0097418)
2.1 6.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
2.1 133.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
2.0 14.3 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306)
2.0 26.0 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
2.0 5.9 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
2.0 35.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.8 16.4 GO:0097413 Lewy body(GO:0097413)
1.8 486.2 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
1.8 10.8 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
1.8 1.8 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
1.8 28.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
1.8 3.5 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
1.8 5.3 GO:1990015 mesaxon(GO:0097453) ensheathing process(GO:1990015)
1.7 8.6 GO:0005594 collagen type IX trimer(GO:0005594)
1.7 8.5 GO:0044530 supraspliceosomal complex(GO:0044530)
1.7 16.8 GO:0030123 AP-3 adaptor complex(GO:0030123)
1.7 1.7 GO:0032585 multivesicular body membrane(GO:0032585)
1.7 21.7 GO:0005869 dynactin complex(GO:0005869)
1.6 3.3 GO:0071203 WASH complex(GO:0071203)
1.6 6.4 GO:0030131 clathrin adaptor complex(GO:0030131)
1.6 11.0 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
1.6 11.0 GO:0070852 cell body fiber(GO:0070852)
1.6 12.5 GO:0035253 ciliary rootlet(GO:0035253)
1.5 6.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
1.5 81.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
1.5 6.2 GO:0005797 Golgi medial cisterna(GO:0005797)
1.5 4.6 GO:0034657 GID complex(GO:0034657)
1.5 32.2 GO:0043198 dendritic shaft(GO:0043198)
1.5 47.3 GO:0030175 filopodium(GO:0030175)
1.5 38.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
1.5 1.5 GO:0035189 Rb-E2F complex(GO:0035189)
1.4 17.4 GO:0008091 spectrin(GO:0008091)
1.4 182.9 GO:0030426 growth cone(GO:0030426)
1.4 4.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
1.4 11.2 GO:0033391 chromatoid body(GO:0033391)
1.4 2.8 GO:0044224 juxtaparanode region of axon(GO:0044224)
1.4 8.2 GO:0001917 photoreceptor inner segment(GO:0001917)
1.4 5.5 GO:0032311 angiogenin-PRI complex(GO:0032311)
1.4 1.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
1.3 27.0 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
1.3 18.9 GO:0097227 sperm annulus(GO:0097227)
1.3 11.7 GO:0031045 dense core granule(GO:0031045)
1.3 18.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
1.3 31.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
1.3 12.6 GO:0005641 nuclear envelope lumen(GO:0005641)
1.2 21.1 GO:0032839 dendrite cytoplasm(GO:0032839)
1.2 3.7 GO:1902636 kinociliary basal body(GO:1902636)
1.2 3.7 GO:0060187 cell pole(GO:0060187)
1.2 73.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
1.2 257.6 GO:0005802 trans-Golgi network(GO:0005802)
1.1 5.7 GO:0000408 EKC/KEOPS complex(GO:0000408)
1.1 2.3 GO:0031985 Golgi cisterna(GO:0031985)
1.1 3.4 GO:0036398 TCR signalosome(GO:0036398)
1.1 7.9 GO:0072487 MSL complex(GO:0072487)
1.1 4.5 GO:0016939 kinesin II complex(GO:0016939)
1.1 12.4 GO:0005614 interstitial matrix(GO:0005614)
1.1 1.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
1.1 1.1 GO:0000502 proteasome complex(GO:0000502)
1.1 2.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
1.1 6.4 GO:0070436 Grb2-EGFR complex(GO:0070436)
1.1 50.3 GO:0005905 clathrin-coated pit(GO:0005905)
1.1 5.3 GO:0042272 nuclear RNA export factor complex(GO:0042272)
1.1 7.4 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
1.0 4.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
1.0 6.0 GO:0032009 early phagosome(GO:0032009)
1.0 3.0 GO:0016013 syntrophin complex(GO:0016013)
1.0 71.2 GO:1904724 tertiary granule lumen(GO:1904724)
1.0 1.9 GO:0033270 paranode region of axon(GO:0033270)
1.0 1.9 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.9 4.7 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.9 15.9 GO:0030056 hemidesmosome(GO:0030056)
0.9 27.5 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.9 5.4 GO:0060076 excitatory synapse(GO:0060076)
0.9 4.5 GO:0016342 catenin complex(GO:0016342)
0.9 16.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.9 13.1 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.9 0.9 GO:0036020 endolysosome membrane(GO:0036020)
0.9 1.7 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.9 12.9 GO:0035371 microtubule plus-end(GO:0035371)
0.9 12.0 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.8 10.2 GO:0000145 exocyst(GO:0000145)
0.8 5.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.8 5.0 GO:0017119 Golgi transport complex(GO:0017119)
0.8 4.1 GO:0036128 CatSper complex(GO:0036128)
0.8 48.3 GO:0008021 synaptic vesicle(GO:0008021)
0.8 4.1 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.8 8.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.8 5.6 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.8 14.4 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.8 58.6 GO:0043204 perikaryon(GO:0043204)
0.8 3.2 GO:0005899 insulin receptor complex(GO:0005899)
0.8 2.4 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.8 32.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.8 29.6 GO:0042734 presynaptic membrane(GO:0042734)
0.8 2.3 GO:0032059 bleb(GO:0032059)
0.8 3.8 GO:0030427 site of polarized growth(GO:0030427)
0.8 9.2 GO:0000815 ESCRT III complex(GO:0000815)
0.8 6.9 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.8 7.7 GO:0099568 cytoplasmic region(GO:0099568)
0.8 4.6 GO:1902560 GMP reductase complex(GO:1902560)
0.8 6.0 GO:0033010 paranodal junction(GO:0033010)
0.7 2.2 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.7 2.9 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.7 17.4 GO:0014704 intercalated disc(GO:0014704)
0.7 43.1 GO:0005776 autophagosome(GO:0005776)
0.7 12.9 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.7 1.4 GO:0043196 varicosity(GO:0043196)
0.7 6.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.7 4.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.7 33.1 GO:0031902 late endosome membrane(GO:0031902)
0.7 4.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.7 2.1 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.7 2.7 GO:0032437 cuticular plate(GO:0032437)
0.7 64.7 GO:0005814 centriole(GO:0005814)
0.7 8.2 GO:0030018 Z disc(GO:0030018)
0.7 3.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.7 42.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.7 2.7 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.7 2.0 GO:0005960 glycine cleavage complex(GO:0005960)
0.7 21.8 GO:0055037 recycling endosome(GO:0055037)
0.7 2.0 GO:0071745 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.6 3.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.6 10.3 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.6 3.2 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.6 9.4 GO:0048786 presynaptic active zone(GO:0048786)
0.6 12.3 GO:0005921 gap junction(GO:0005921)
0.6 42.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.6 8.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.6 3.0 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.6 2.4 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.6 54.7 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.6 31.0 GO:0005770 late endosome(GO:0005770)
0.6 1.7 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.6 3.5 GO:0061700 GATOR2 complex(GO:0061700)
0.6 1.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.6 317.5 GO:0000139 Golgi membrane(GO:0000139)
0.6 6.2 GO:0035869 ciliary transition zone(GO:0035869)
0.6 13.5 GO:1904115 axon cytoplasm(GO:1904115)
0.6 1.7 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.6 2.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.6 1.7 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.6 14.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.6 101.9 GO:0030027 lamellipodium(GO:0030027)
0.5 1.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.5 8.5 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.5 31.7 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.5 2.6 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.5 10.5 GO:0097228 sperm principal piece(GO:0097228)
0.5 11.5 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.5 2.6 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.5 9.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.5 31.3 GO:0030496 midbody(GO:0030496)
0.5 5.0 GO:0070187 telosome(GO:0070187)
0.5 0.5 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.5 52.3 GO:0031225 anchored component of membrane(GO:0031225)
0.5 2.0 GO:0070695 FHF complex(GO:0070695)
0.5 1.9 GO:0071001 U4/U6 snRNP(GO:0071001)
0.5 31.1 GO:0030133 transport vesicle(GO:0030133)
0.5 43.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.5 6.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.5 2.9 GO:0051233 spindle midzone(GO:0051233)
0.5 4.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.5 10.4 GO:0031982 vesicle(GO:0031982)
0.5 7.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.5 2.3 GO:0001940 male pronucleus(GO:0001940)
0.5 63.0 GO:0043209 myelin sheath(GO:0043209)
0.5 14.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.4 59.7 GO:0010008 endosome membrane(GO:0010008)
0.4 113.0 GO:0005874 microtubule(GO:0005874)
0.4 1.3 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.4 6.0 GO:0008180 COP9 signalosome(GO:0008180)
0.4 1.3 GO:0097165 nuclear stress granule(GO:0097165)
0.4 14.6 GO:0098793 presynapse(GO:0098793)
0.4 0.4 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.4 0.4 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.4 1.2 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.4 5.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.4 1.2 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.4 1.6 GO:0019867 outer membrane(GO:0019867)
0.4 8.3 GO:0042101 T cell receptor complex(GO:0042101)
0.4 1.9 GO:0089701 U2AF(GO:0089701)
0.4 1.1 GO:0034464 BBSome(GO:0034464)
0.4 2.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.4 0.4 GO:0005773 vacuole(GO:0005773)
0.4 10.2 GO:0005903 brush border(GO:0005903)
0.4 0.7 GO:0072687 meiotic spindle(GO:0072687)
0.4 1.4 GO:0045177 apical part of cell(GO:0045177)
0.3 25.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.3 46.9 GO:0019898 extrinsic component of membrane(GO:0019898)
0.3 0.7 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.3 1.7 GO:0016461 unconventional myosin complex(GO:0016461)
0.3 5.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.3 1.9 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.3 1.0 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.3 1.0 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.3 1.6 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.3 15.2 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.3 2.1 GO:0016272 prefoldin complex(GO:0016272)
0.3 2.1 GO:0097361 CIA complex(GO:0097361)
0.3 0.9 GO:0044447 axoneme part(GO:0044447)
0.3 5.4 GO:0036126 sperm flagellum(GO:0036126)
0.3 1.5 GO:0034457 Mpp10 complex(GO:0034457)
0.3 33.5 GO:0005774 vacuolar membrane(GO:0005774)
0.3 0.8 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.3 55.7 GO:0045202 synapse(GO:0045202)
0.3 3.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.3 1.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.3 0.3 GO:0031085 BLOC-3 complex(GO:0031085)
0.3 1.0 GO:0032044 DSIF complex(GO:0032044)
0.2 2.0 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.2 0.5 GO:0002079 inner acrosomal membrane(GO:0002079)
0.2 2.9 GO:0035631 CD40 receptor complex(GO:0035631)
0.2 0.5 GO:0002177 manchette(GO:0002177)
0.2 4.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 0.9 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 0.2 GO:0030904 retromer complex(GO:0030904)
0.2 3.3 GO:0030057 desmosome(GO:0030057)
0.2 2.9 GO:0046930 pore complex(GO:0046930)
0.2 0.6 GO:0005593 FACIT collagen trimer(GO:0005593)
0.2 1.5 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.2 0.8 GO:1990246 uniplex complex(GO:1990246)
0.2 0.8 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.2 3.7 GO:0001772 immunological synapse(GO:0001772)
0.2 2.3 GO:0000812 Swr1 complex(GO:0000812)
0.2 1.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 0.7 GO:0033263 CORVET complex(GO:0033263)
0.2 1.2 GO:0031931 TORC1 complex(GO:0031931)
0.2 0.7 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 21.3 GO:0016605 PML body(GO:0016605)
0.2 1.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.2 3.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.2 1.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 3.8 GO:0016324 apical plasma membrane(GO:0016324)
0.2 5.3 GO:0036064 ciliary basal body(GO:0036064)
0.1 0.4 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.1 16.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 0.4 GO:0044423 virion(GO:0019012) virion part(GO:0044423)
0.1 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.1 2.0 GO:0097342 ripoptosome(GO:0097342)
0.1 13.0 GO:0031253 cell projection membrane(GO:0031253)
0.1 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.1 1.8 GO:0042629 mast cell granule(GO:0042629)
0.1 3.0 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.3 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 7.4 GO:0005769 early endosome(GO:0005769)
0.1 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.2 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.1 1.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 2.8 GO:0070469 respiratory chain(GO:0070469)
0.1 11.2 GO:0030424 axon(GO:0030424)
0.1 2.4 GO:0035580 specific granule lumen(GO:0035580)
0.1 0.1 GO:0071817 MMXD complex(GO:0071817)
0.1 8.2 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 0.4 GO:0061617 MICOS complex(GO:0061617)
0.1 5.1 GO:0000786 nucleosome(GO:0000786)
0.1 0.8 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 2.5 GO:0005924 cell-substrate adherens junction(GO:0005924)
0.1 2.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 4.4 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 0.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.2 GO:0071546 pi-body(GO:0071546)
0.1 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.0 GO:0097546 ciliary base(GO:0097546)
0.1 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.1 1.9 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.3 GO:0009986 cell surface(GO:0009986)
0.1 1.1 GO:0072686 mitotic spindle(GO:0072686)
0.1 1.0 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.7 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.0 GO:0042587 glycogen granule(GO:0042587)
0.0 0.6 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 2.2 GO:0031252 cell leading edge(GO:0031252)
0.0 1.6 GO:0000922 spindle pole(GO:0000922)
0.0 3.3 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.4 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0032838 cell projection cytoplasm(GO:0032838)
0.0 0.2 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.4 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.7 GO:0031300 intrinsic component of organelle membrane(GO:0031300)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 10.7 GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network(GO:0042175)
0.0 0.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0005602 complement component C1 complex(GO:0005602)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
12.7 38.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
12.4 37.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
12.1 36.2 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
11.9 35.7 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
11.4 34.2 GO:0052726 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
10.3 62.0 GO:1903135 cupric ion binding(GO:1903135)
9.6 28.7 GO:0032184 SUMO polymer binding(GO:0032184)
8.1 32.3 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
7.9 23.6 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
7.7 23.0 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
7.6 22.8 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
7.6 106.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
7.2 28.9 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
6.9 83.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
6.8 13.6 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
6.7 26.8 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
6.5 45.8 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
6.5 39.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
6.3 37.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
6.0 66.3 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
6.0 35.8 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
5.9 35.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
5.8 35.0 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
5.7 113.9 GO:0050780 dopamine receptor binding(GO:0050780)
5.6 33.6 GO:0052811 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811)
5.4 21.5 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
5.1 25.3 GO:0070404 NADH binding(GO:0070404)
5.0 29.7 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
4.8 19.4 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
4.8 14.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
4.6 32.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
4.5 31.7 GO:0050815 phosphoserine binding(GO:0050815)
4.2 129.8 GO:0017075 syntaxin-1 binding(GO:0017075)
4.1 37.1 GO:0032051 clathrin light chain binding(GO:0032051)
4.1 16.4 GO:0099609 microtubule lateral binding(GO:0099609)
4.1 20.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
4.1 12.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
4.0 16.0 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
3.8 18.9 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
3.7 73.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
3.6 21.9 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
3.6 14.4 GO:0035939 microsatellite binding(GO:0035939)
3.6 99.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
3.5 10.5 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
3.5 17.4 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
3.4 13.8 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
3.4 6.8 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
3.4 16.8 GO:0050816 phosphothreonine binding(GO:0050816)
3.3 98.4 GO:0071889 14-3-3 protein binding(GO:0071889)
3.3 6.6 GO:0019770 IgG receptor activity(GO:0019770)
3.3 9.8 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
3.2 22.5 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596)
3.2 85.7 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
3.2 34.9 GO:0031681 G-protein beta-subunit binding(GO:0031681)
3.2 56.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
3.1 40.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
3.1 49.7 GO:0008179 adenylate cyclase binding(GO:0008179)
3.1 15.3 GO:0016403 dimethylargininase activity(GO:0016403)
3.0 12.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
3.0 30.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
3.0 6.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
3.0 9.0 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
3.0 53.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
3.0 14.8 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
3.0 17.7 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
2.9 23.5 GO:0004064 arylesterase activity(GO:0004064)
2.9 11.6 GO:0043398 HLH domain binding(GO:0043398)
2.9 31.7 GO:0048156 tau protein binding(GO:0048156)
2.9 17.2 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
2.9 17.2 GO:0003998 acylphosphatase activity(GO:0003998)
2.9 11.4 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
2.8 8.5 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
2.8 11.3 GO:0004850 uridine phosphorylase activity(GO:0004850)
2.8 55.0 GO:0030955 potassium ion binding(GO:0030955)
2.7 8.2 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
2.7 27.1 GO:0030911 TPR domain binding(GO:0030911)
2.7 10.7 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
2.7 23.9 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
2.6 118.6 GO:0003785 actin monomer binding(GO:0003785)
2.6 49.5 GO:0045504 dynein heavy chain binding(GO:0045504)
2.6 28.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
2.6 13.0 GO:0034046 poly(G) binding(GO:0034046)
2.6 12.9 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
2.5 7.6 GO:0032427 GBD domain binding(GO:0032427)
2.5 43.1 GO:0043495 protein anchor(GO:0043495)
2.5 73.6 GO:0043014 alpha-tubulin binding(GO:0043014)
2.5 22.7 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
2.5 25.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
2.5 10.0 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
2.5 2.5 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
2.5 37.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
2.5 24.8 GO:1903136 cuprous ion binding(GO:1903136)
2.5 19.7 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
2.5 9.8 GO:0004427 inorganic diphosphatase activity(GO:0004427)
2.5 4.9 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
2.4 2.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
2.4 11.9 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
2.4 59.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
2.4 40.2 GO:0005522 profilin binding(GO:0005522)
2.4 35.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
2.4 18.8 GO:0043008 ATP-dependent protein binding(GO:0043008)
2.3 7.0 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
2.3 16.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
2.3 16.4 GO:0016015 morphogen activity(GO:0016015)
2.3 62.8 GO:0051010 microtubule plus-end binding(GO:0051010)
2.3 6.9 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
2.3 13.8 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
2.3 9.2 GO:0031716 calcitonin receptor binding(GO:0031716)
2.3 6.8 GO:0070025 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
2.3 22.5 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
2.2 13.2 GO:0034452 dynactin binding(GO:0034452)
2.2 8.8 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
2.2 17.4 GO:0004111 creatine kinase activity(GO:0004111)
2.2 159.6 GO:0001540 beta-amyloid binding(GO:0001540)
2.1 34.2 GO:0016805 dipeptidase activity(GO:0016805)
2.1 15.0 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
2.1 47.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
2.1 6.3 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
2.1 35.8 GO:0031005 filamin binding(GO:0031005)
2.1 10.5 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
2.1 8.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
2.1 10.4 GO:0045134 uridine-diphosphatase activity(GO:0045134)
2.1 26.9 GO:0097109 neuroligin family protein binding(GO:0097109)
2.1 6.2 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
2.0 16.3 GO:0034235 GPI anchor binding(GO:0034235)
2.0 14.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
2.0 24.4 GO:0031386 protein tag(GO:0031386)
2.0 6.0 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
2.0 42.0 GO:0050811 GABA receptor binding(GO:0050811)
2.0 10.0 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
2.0 9.9 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
2.0 9.8 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
2.0 11.7 GO:0003872 6-phosphofructokinase activity(GO:0003872)
1.9 7.8 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
1.9 30.8 GO:0008432 JUN kinase binding(GO:0008432)
1.9 47.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
1.9 7.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
1.8 5.5 GO:0004949 cannabinoid receptor activity(GO:0004949)
1.8 7.4 GO:0004530 deoxyribonuclease I activity(GO:0004530)
1.8 23.7 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
1.8 16.4 GO:0030552 cAMP binding(GO:0030552)
1.8 5.5 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
1.8 9.1 GO:0097016 L27 domain binding(GO:0097016)
1.8 18.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
1.8 49.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
1.8 3.6 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
1.8 7.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
1.8 5.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
1.8 5.4 GO:0036317 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
1.8 8.9 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
1.8 5.3 GO:0051011 microtubule minus-end binding(GO:0051011)
1.8 35.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
1.7 5.2 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
1.7 1.7 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
1.7 50.1 GO:0043015 gamma-tubulin binding(GO:0043015)
1.7 8.6 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
1.7 71.5 GO:0046875 ephrin receptor binding(GO:0046875)
1.7 5.1 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
1.7 10.0 GO:0039552 RIG-I binding(GO:0039552)
1.7 3.3 GO:0017089 glycolipid transporter activity(GO:0017089)
1.6 4.8 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
1.6 4.8 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
1.6 7.9 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
1.6 6.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
1.6 7.9 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
1.6 10.9 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
1.6 4.7 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
1.6 45.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
1.5 10.8 GO:0001727 lipid kinase activity(GO:0001727)
1.5 4.6 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
1.5 21.5 GO:0031489 myosin V binding(GO:0031489)
1.5 24.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
1.5 1.5 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
1.5 22.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
1.5 6.0 GO:0097001 ceramide binding(GO:0097001)
1.5 3.0 GO:0042903 tubulin deacetylase activity(GO:0042903)
1.5 21.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
1.5 12.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
1.5 26.8 GO:0070300 phosphatidic acid binding(GO:0070300)
1.5 14.9 GO:0046870 cadmium ion binding(GO:0046870)
1.5 16.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.5 4.4 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
1.4 101.1 GO:0019003 GDP binding(GO:0019003)
1.4 7.1 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
1.4 4.3 GO:0004137 deoxycytidine kinase activity(GO:0004137)
1.4 11.3 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
1.4 1.4 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
1.4 4.1 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
1.4 8.2 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
1.4 5.4 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
1.4 29.7 GO:0030506 ankyrin binding(GO:0030506)
1.4 5.4 GO:0034057 RNA strand-exchange activity(GO:0034057)
1.4 4.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
1.3 5.2 GO:0032794 GTPase activating protein binding(GO:0032794)
1.3 5.2 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
1.3 3.9 GO:0004103 choline kinase activity(GO:0004103)
1.3 7.6 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
1.3 21.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
1.3 2.5 GO:0050321 tau-protein kinase activity(GO:0050321)
1.2 1.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
1.2 2.5 GO:0015235 cobalamin transporter activity(GO:0015235)
1.2 7.4 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
1.2 3.7 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
1.2 9.8 GO:0000182 rDNA binding(GO:0000182)
1.2 3.7 GO:0070728 leucine binding(GO:0070728)
1.2 3.6 GO:0033149 FFAT motif binding(GO:0033149)
1.2 3.6 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
1.2 14.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
1.2 47.1 GO:0030507 spectrin binding(GO:0030507)
1.2 9.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
1.2 3.5 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
1.2 26.7 GO:0004062 aryl sulfotransferase activity(GO:0004062)
1.2 16.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.1 8.0 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
1.1 1.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
1.1 4.5 GO:0015232 heme transporter activity(GO:0015232)
1.1 5.6 GO:0004906 interferon-gamma receptor activity(GO:0004906)
1.1 265.6 GO:0003924 GTPase activity(GO:0003924)
1.1 14.1 GO:0070840 dynein complex binding(GO:0070840)
1.1 45.3 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
1.1 9.7 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
1.1 4.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
1.1 24.7 GO:0004383 guanylate cyclase activity(GO:0004383)
1.1 3.2 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
1.1 160.6 GO:0044325 ion channel binding(GO:0044325)
1.1 10.6 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
1.1 4.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
1.1 25.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
1.0 4.2 GO:0004771 sterol esterase activity(GO:0004771)
1.0 10.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
1.0 3.1 GO:0052895 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
1.0 13.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
1.0 4.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
1.0 5.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
1.0 1.0 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
1.0 3.9 GO:0008184 glycogen phosphorylase activity(GO:0008184)
1.0 3.9 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
1.0 1.0 GO:0031692 alpha-1B adrenergic receptor binding(GO:0031692)
1.0 42.9 GO:0003777 microtubule motor activity(GO:0003777)
1.0 4.9 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
1.0 42.6 GO:0070412 R-SMAD binding(GO:0070412)
1.0 8.7 GO:0051425 PTB domain binding(GO:0051425)
1.0 3.8 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
1.0 17.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.9 2.8 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.9 10.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.9 9.3 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.9 2.8 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.9 18.2 GO:0005521 lamin binding(GO:0005521)
0.9 5.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.9 2.7 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.9 2.6 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.9 7.9 GO:0043426 MRF binding(GO:0043426)
0.9 25.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.9 5.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.9 31.0 GO:0050699 WW domain binding(GO:0050699)
0.9 2.6 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.9 4.3 GO:0004359 glutaminase activity(GO:0004359)
0.8 4.2 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.8 9.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.8 5.9 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.8 1.7 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.8 5.0 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.8 8.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.8 3.3 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.8 22.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.8 4.1 GO:0070097 delta-catenin binding(GO:0070097)
0.8 16.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.8 1.6 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.8 2.4 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.8 1.6 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.8 23.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.8 21.0 GO:0015248 sterol transporter activity(GO:0015248)
0.8 3.9 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.8 21.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.8 34.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.8 4.6 GO:0008443 phosphofructokinase activity(GO:0008443)
0.8 4.6 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.8 5.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.8 2.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.8 3.0 GO:0008410 CoA-transferase activity(GO:0008410)
0.8 5.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.8 17.3 GO:0042169 SH2 domain binding(GO:0042169)
0.8 3.0 GO:0009881 photoreceptor activity(GO:0009881)
0.7 1.5 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.7 17.0 GO:0004806 triglyceride lipase activity(GO:0004806)
0.7 9.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.7 11.0 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.7 31.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.7 5.0 GO:0030957 Tat protein binding(GO:0030957)
0.7 11.5 GO:0005112 Notch binding(GO:0005112)
0.7 97.7 GO:0017124 SH3 domain binding(GO:0017124)
0.7 13.6 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.7 1.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.7 0.7 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.7 7.8 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.7 5.7 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.7 12.8 GO:0035198 miRNA binding(GO:0035198)
0.7 91.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.7 2.1 GO:0034191 apolipoprotein receptor binding(GO:0034190) apolipoprotein A-I receptor binding(GO:0034191)
0.7 2.8 GO:0017040 ceramidase activity(GO:0017040)
0.7 23.8 GO:0017048 Rho GTPase binding(GO:0017048)
0.7 7.0 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.7 0.7 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.7 1.4 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.7 47.6 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820)
0.7 4.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.7 5.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.7 8.9 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.7 7.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.7 2.7 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.7 2.7 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.7 5.3 GO:0019863 IgE binding(GO:0019863)
0.7 9.1 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.7 1.3 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.7 9.8 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.6 4.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.6 6.4 GO:0004075 biotin carboxylase activity(GO:0004075)
0.6 3.2 GO:0045159 myosin II binding(GO:0045159)
0.6 6.3 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.6 6.9 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.6 6.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.6 8.1 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.6 15.4 GO:0001671 ATPase activator activity(GO:0001671)
0.6 2.5 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.6 1.8 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.6 1.8 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.6 5.4 GO:0051787 misfolded protein binding(GO:0051787)
0.6 1.8 GO:0031685 adenosine receptor binding(GO:0031685)
0.6 5.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.6 2.9 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.6 4.7 GO:0008131 primary amine oxidase activity(GO:0008131)
0.6 4.1 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.6 6.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.6 1.1 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.6 2.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.6 22.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.6 2.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.6 2.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.5 18.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.5 1.6 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.5 2.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.5 7.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.5 2.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.5 1.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.5 2.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
0.5 10.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.5 1.6 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.5 2.6 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.5 2.6 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.5 1.6 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.5 2.0 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.5 1.5 GO:0035662 Toll-like receptor 4 binding(GO:0035662) Toll-like receptor 2 binding(GO:0035663)
0.5 3.0 GO:0016778 diphosphotransferase activity(GO:0016778)
0.5 6.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.5 3.0 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.5 10.5 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.5 2.0 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.5 1.5 GO:0003953 NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
0.5 5.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.5 3.9 GO:0097322 7SK snRNA binding(GO:0097322)
0.5 182.4 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.5 4.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.5 0.5 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.5 2.9 GO:1990405 protein antigen binding(GO:1990405)
0.5 1.5 GO:0045499 chemorepellent activity(GO:0045499)
0.5 3.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.5 0.5 GO:1904288 BAT3 complex binding(GO:1904288)
0.5 4.3 GO:0046790 virion binding(GO:0046790)
0.5 0.9 GO:0000035 acyl binding(GO:0000035)
0.5 49.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.5 3.3 GO:0035254 glutamate receptor binding(GO:0035254)
0.5 3.7 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.5 48.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.5 2.3 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.5 11.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.5 28.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.5 0.5 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.4 28.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.4 2.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.4 2.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.4 0.4 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.4 14.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.4 1.3 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.4 38.2 GO:0005525 GTP binding(GO:0005525)
0.4 2.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.4 54.7 GO:0051015 actin filament binding(GO:0051015)
0.4 1.3 GO:0050733 RS domain binding(GO:0050733)
0.4 0.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.4 1.6 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.4 13.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.4 2.0 GO:0008097 5S rRNA binding(GO:0008097)
0.4 2.0 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.4 1.2 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.4 0.8 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.4 0.8 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.4 8.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.4 3.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.4 0.8 GO:0035325 Toll-like receptor binding(GO:0035325)
0.4 0.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.4 1.5 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.4 1.5 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.4 17.3 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.4 22.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.4 10.8 GO:0005123 death receptor binding(GO:0005123)
0.4 1.1 GO:0032090 Pyrin domain binding(GO:0032090)
0.4 8.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.4 1.8 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.4 0.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.4 1.5 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.4 2.9 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.4 1.8 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.4 3.6 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.4 0.4 GO:0004630 phospholipase D activity(GO:0004630)
0.4 1.1 GO:0045174 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.4 2.8 GO:0030276 clathrin binding(GO:0030276)
0.4 10.2 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3 0.7 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.3 1.3 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.3 1.0 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.3 0.3 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.3 5.8 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.3 1.3 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.3 5.8 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.3 29.0 GO:0005516 calmodulin binding(GO:0005516)
0.3 1.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 1.2 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.3 0.9 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.3 1.5 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.3 9.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.3 1.2 GO:0003951 NAD+ kinase activity(GO:0003951)
0.3 0.9 GO:0015616 DNA translocase activity(GO:0015616)
0.3 1.5 GO:0019239 deaminase activity(GO:0019239)
0.3 2.7 GO:0030332 cyclin binding(GO:0030332)
0.3 4.5 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.3 1.8 GO:0048039 ubiquinone binding(GO:0048039)
0.3 0.9 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.3 0.3 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.3 5.9 GO:0015929 hexosaminidase activity(GO:0015929)
0.3 0.8 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.3 3.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 1.1 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.3 2.2 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.3 0.6 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.3 3.9 GO:0030275 LRR domain binding(GO:0030275)
0.3 0.8 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.3 1.3 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.3 54.7 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.3 14.0 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.3 4.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.3 1.8 GO:0015205 nucleobase transmembrane transporter activity(GO:0015205)
0.3 0.8 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.3 1.0 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
0.3 3.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 1.8 GO:0038132 neuregulin binding(GO:0038132)
0.2 2.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 1.5 GO:0030274 LIM domain binding(GO:0030274)
0.2 0.7 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.2 0.5 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.2 0.7 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.2 0.2 GO:0043492 ATPase activity, coupled to movement of substances(GO:0043492)
0.2 1.7 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.2 1.2 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.2 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.2 5.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 0.9 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.2 1.6 GO:0032393 MHC class I receptor activity(GO:0032393)
0.2 0.7 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.2 38.8 GO:0030695 GTPase regulator activity(GO:0030695)
0.2 0.4 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 0.7 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.2 0.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673)
0.2 0.8 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.2 29.5 GO:0003779 actin binding(GO:0003779)
0.2 0.6 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.2 1.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.2 0.2 GO:0043532 angiostatin binding(GO:0043532)
0.2 0.6 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.2 0.8 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.2 1.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.2 1.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 0.6 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.2 0.4 GO:0009374 biotin binding(GO:0009374)
0.2 2.5 GO:0005003 ephrin receptor activity(GO:0005003)
0.2 0.8 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.2 0.6 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.2 2.6 GO:0043295 glutathione binding(GO:0043295)
0.2 0.6 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.2 3.7 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701)
0.2 1.1 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.2 0.4 GO:0030151 molybdenum ion binding(GO:0030151)
0.2 0.5 GO:0019787 ubiquitin-like protein transferase activity(GO:0019787)
0.2 0.2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.2 1.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2 0.5 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.2 0.5 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.2 0.5 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 1.8 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.2 0.7 GO:0019203 carbohydrate phosphatase activity(GO:0019203) sugar-phosphatase activity(GO:0050308)
0.2 0.7 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.2 1.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.2 0.7 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.2 0.7 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.2 0.7 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.2 1.0 GO:0001515 opioid peptide activity(GO:0001515)
0.2 1.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 0.3 GO:0044389 ubiquitin-like protein ligase binding(GO:0044389)
0.2 0.5 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.2 0.5 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.2 5.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.9 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 1.6 GO:0008061 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.1 0.6 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.1 1.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.3 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.1 0.4 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.5 GO:0043422 protein kinase B binding(GO:0043422)
0.1 0.1 GO:0043559 insulin binding(GO:0043559)
0.1 0.4 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.1 2.1 GO:0019841 retinol binding(GO:0019841)
0.1 0.6 GO:0031701 angiotensin receptor binding(GO:0031701)
0.1 0.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.5 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 3.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.5 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.4 GO:0004877 complement component C4b binding(GO:0001855) complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.1 0.8 GO:0003774 motor activity(GO:0003774)
0.1 0.4 GO:0048030 disaccharide binding(GO:0048030)
0.1 1.4 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 0.5 GO:0004803 transposase activity(GO:0004803)
0.1 0.3 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.1 0.6 GO:0001848 complement binding(GO:0001848)
0.1 0.2 GO:0046978 TAP binding(GO:0046977) TAP1 binding(GO:0046978)
0.1 0.8 GO:0042923 neuropeptide binding(GO:0042923)
0.1 0.7 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.6 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.9 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.5 GO:0098960 postsynaptic neurotransmitter receptor activity(GO:0098960)
0.1 0.3 GO:0046625 sphingolipid binding(GO:0046625)
0.1 0.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.3 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 0.7 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 0.1 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 8.7 GO:0008017 microtubule binding(GO:0008017)
0.1 0.5 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 0.2 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 0.6 GO:0052744 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.1 0.2 GO:0015923 mannosidase activity(GO:0015923)
0.1 4.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.2 GO:0030350 iron-responsive element binding(GO:0030350)
0.1 0.4 GO:0015288 porin activity(GO:0015288)
0.1 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 1.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 0.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 0.2 GO:0004913 interleukin-4 receptor activity(GO:0004913)
0.1 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.3 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.1 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.4 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.2 GO:0008940 nitrate reductase activity(GO:0008940)
0.1 0.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.1 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 1.0 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.2 GO:0008312 7S RNA binding(GO:0008312)
0.1 0.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.2 GO:0008513 secondary active organic cation transmembrane transporter activity(GO:0008513)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.1 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.3 GO:0034711 inhibin binding(GO:0034711)
0.0 0.7 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.2 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 1.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.5 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.0 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.1 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.0 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.1 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.7 GO:0015631 tubulin binding(GO:0015631)
0.0 0.1 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.0 0.0 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 1.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.1 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.1 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.2 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884) lipopeptide binding(GO:0071723)
0.0 0.0 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.3 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.0 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.3 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 1.4 GO:0005543 phospholipid binding(GO:0005543)
0.0 0.1 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.0 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.0 GO:0030305 heparanase activity(GO:0030305)
0.0 0.0 GO:0016803 ether hydrolase activity(GO:0016803)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 93.6 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
4.2 171.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
3.3 20.0 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
3.0 51.0 PID S1P S1P4 PATHWAY S1P4 pathway
3.0 106.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
2.9 158.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
2.7 16.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
2.7 27.2 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
2.6 34.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
2.4 94.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
2.4 4.8 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
2.2 13.5 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
2.0 60.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
2.0 137.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
1.8 132.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
1.6 40.4 PID REELIN PATHWAY Reelin signaling pathway
1.5 56.6 PID NCADHERIN PATHWAY N-cadherin signaling events
1.5 88.6 PID RHOA REG PATHWAY Regulation of RhoA activity
1.4 2.9 PID IFNG PATHWAY IFN-gamma pathway
1.4 26.0 PID LPA4 PATHWAY LPA4-mediated signaling events
1.3 68.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
1.2 62.7 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
1.2 27.4 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
1.2 38.7 PID ARF6 PATHWAY Arf6 signaling events
1.1 55.4 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
1.0 44.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.9 16.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.9 4.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.8 8.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.8 11.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.8 9.5 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.8 17.3 PID ARF 3PATHWAY Arf1 pathway
0.8 27.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.7 25.2 PID AURORA A PATHWAY Aurora A signaling
0.7 45.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.7 15.2 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.7 80.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.7 14.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.6 3.8 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.6 13.9 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.6 32.4 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.6 3.1 PID INSULIN PATHWAY Insulin Pathway
0.6 6.4 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.6 16.8 PID GLYPICAN 1PATHWAY Glypican 1 network
0.6 51.6 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.5 11.4 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.5 36.0 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.5 2.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.5 1.6 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.5 21.4 PID LKB1 PATHWAY LKB1 signaling events
0.5 3.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.5 12.1 PID RAS PATHWAY Regulation of Ras family activation
0.5 18.0 PID FGF PATHWAY FGF signaling pathway
0.5 23.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.5 18.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.5 9.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.5 9.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.5 1.8 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.4 3.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.4 3.7 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.4 13.4 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.4 3.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.3 83.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.3 2.4 PID CD40 PATHWAY CD40/CD40L signaling
0.3 2.4 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.3 6.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.3 1.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.3 3.8 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.3 1.8 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.3 9.5 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.3 3.7 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.2 1.7 PID IL5 PATHWAY IL5-mediated signaling events
0.2 6.8 PID P53 REGULATION PATHWAY p53 pathway
0.2 1.6 ST GAQ PATHWAY G alpha q Pathway
0.2 6.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.2 4.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 4.5 PID SHP2 PATHWAY SHP2 signaling
0.2 4.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.2 3.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2 4.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 0.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 0.3 ST STAT3 PATHWAY STAT3 Pathway
0.1 1.7 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 2.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 3.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 2.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 1.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 2.6 PID IL1 PATHWAY IL1-mediated signaling events
0.1 1.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 0.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 1.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 1.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 2.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 4.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 0.4 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 1.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 1.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.1 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 81.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
5.5 99.6 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
4.9 97.7 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
4.1 199.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
4.1 32.4 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
4.0 109.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
4.0 110.9 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
3.8 19.0 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
3.4 167.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
3.3 46.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
3.0 163.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
3.0 84.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
2.9 77.9 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
2.8 50.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
2.8 80.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
2.4 85.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
2.4 7.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
2.3 25.8 REACTOME OPSINS Genes involved in Opsins
2.3 29.7 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
2.3 76.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
2.1 23.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
2.0 40.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
2.0 34.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
1.9 85.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
1.9 40.8 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
1.9 41.7 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
1.8 18.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
1.7 19.9 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
1.6 50.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
1.6 19.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
1.6 48.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
1.6 25.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
1.6 20.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
1.5 50.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.5 13.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
1.5 29.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
1.5 16.0 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
1.4 168.6 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
1.4 5.7 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
1.4 13.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
1.4 4.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
1.3 5.1 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
1.2 196.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
1.1 21.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
1.1 17.1 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
1.1 42.1 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
1.1 5.4 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
1.1 5.3 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
1.1 16.8 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
1.0 21.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
1.0 15.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
1.0 5.1 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
1.0 11.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
1.0 41.6 REACTOME PROTEIN FOLDING Genes involved in Protein folding
1.0 1.0 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
1.0 14.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
1.0 23.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
1.0 21.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
1.0 34.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
1.0 3.9 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
1.0 17.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.9 11.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.9 7.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.9 20.2 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.9 10.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.9 16.4 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.9 46.3 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.9 24.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.8 16.8 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.8 19.9 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.8 7.8 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.8 29.5 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.7 64.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.7 29.0 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.7 13.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.7 22.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.7 7.8 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.7 2.1 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.6 8.1 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.6 5.2 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.6 5.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.6 2.9 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.6 18.3 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.5 4.7 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.5 17.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.5 6.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.5 24.6 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.5 3.8 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.5 3.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.5 1.8 REACTOME PI METABOLISM Genes involved in PI Metabolism
0.5 1.8 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.4 9.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.4 3.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.4 20.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.4 9.0 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.4 3.3 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.4 9.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.4 0.4 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.4 8.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.3 0.7 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.3 2.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.3 26.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.3 2.5 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.3 4.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.3 6.4 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.3 5.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.3 0.5 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.3 2.8 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.3 2.6 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.3 3.5 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.2 26.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 1.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.2 4.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 21.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.2 4.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 3.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 13.4 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.2 31.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.2 4.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 5.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2 6.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 6.2 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.2 2.3 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.1 0.9 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.1 1.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.0 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 3.1 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.1 1.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 1.5 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.1 1.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 3.0 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 1.0 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 1.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 2.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 0.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.3 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 3.5 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 2.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 0.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 3.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 0.4 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 2.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.2 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.2 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 4.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.4 REACTOME PHOSPHOLIPID METABOLISM Genes involved in Phospholipid metabolism