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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for SPDEF

Z-value: 1.46

Motif logo

Transcription factors associated with SPDEF

Gene Symbol Gene ID Gene Info
ENSG00000124664.6 SAM pointed domain containing ETS transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPDEFhg19_v2_chr6_-_34524093_34524135-0.362.9e-08Click!

Activity profile of SPDEF motif

Sorted Z-values of SPDEF motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_56082455 50.34 ENST00000578794.1
Uncharacterized protein
chr14_-_69864993 46.16 ENST00000555373.1
enhancer of rudimentary homolog (Drosophila)
chr2_+_198380763 37.67 ENST00000448447.2
ENST00000409360.1
MOB family member 4, phocein
chr14_-_24615805 35.02 ENST00000560410.1
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr12_-_102513843 33.35 ENST00000551744.2
ENST00000552283.1
nucleoporin 37kDa
chr1_+_84944926 27.56 ENST00000370656.1
ENST00000370654.5
ribosome production factor 1 homolog (S. cerevisiae)
chr14_-_64010046 27.46 ENST00000337537.3
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr15_-_59949693 27.00 ENST00000396063.1
ENST00000396064.3
ENST00000484743.1
ENST00000559706.1
ENST00000396060.2
general transcription factor IIA, 2, 12kDa
chr1_-_193028632 26.30 ENST00000421683.1
ubiquitin carboxyl-terminal hydrolase L5
chr8_-_101964265 26.07 ENST00000395958.2
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr10_-_120840309 25.81 ENST00000369144.3
eukaryotic translation initiation factor 3, subunit A
chrX_-_135962876 25.22 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RNA binding motif protein, X-linked
chr1_-_43638168 25.06 ENST00000431635.2
EBNA1 binding protein 2
chr5_+_110074685 24.96 ENST00000355943.3
ENST00000447245.2
solute carrier family 25, member 46
chr15_-_59949667 24.46 ENST00000396061.1
general transcription factor IIA, 2, 12kDa
chr17_+_65713925 23.73 ENST00000253247.4
nucleolar protein 11
chr1_-_193028621 23.68 ENST00000367455.4
ENST00000367454.1
ubiquitin carboxyl-terminal hydrolase L5
chr1_+_110091189 23.22 ENST00000369851.4
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr14_-_23058063 22.95 ENST00000538631.1
ENST00000543337.1
ENST00000250498.4
defender against cell death 1
chr2_+_198380289 22.87 ENST00000233892.4
ENST00000409916.1
MOB family member 4, phocein
chr14_+_75348592 22.71 ENST00000334220.4
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr15_-_65282232 22.18 ENST00000416889.2
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr14_-_67826486 22.04 ENST00000555431.1
ENST00000554236.1
ENST00000555474.1
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr1_-_67896069 21.93 ENST00000370995.2
ENST00000361219.6
SERPINE1 mRNA binding protein 1
chr5_+_892745 21.23 ENST00000166345.3
thyroid hormone receptor interactor 13
chr1_-_43637915 21.19 ENST00000236051.2
EBNA1 binding protein 2
chr11_-_46142948 21.05 ENST00000257821.4
PHD finger protein 21A
chr17_-_62658186 20.92 ENST00000262435.9
SMAD specific E3 ubiquitin protein ligase 2
chr1_-_67896095 20.51 ENST00000370994.4
SERPINE1 mRNA binding protein 1
chr1_-_67896009 20.22 ENST00000370990.5
SERPINE1 mRNA binding protein 1
chr15_-_65282274 20.09 ENST00000204566.2
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr14_-_24615523 20.04 ENST00000559056.1
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chrX_+_47053208 19.70 ENST00000442035.1
ENST00000457753.1
ENST00000335972.6
ubiquitin-like modifier activating enzyme 1
chr12_+_69080734 19.68 ENST00000378905.2
nucleoporin 107kDa
chr1_-_19811996 18.74 ENST00000264203.3
ENST00000401084.2
capping protein (actin filament) muscle Z-line, beta
chr14_+_35761580 18.70 ENST00000553809.1
ENST00000555764.1
ENST00000556506.1
proteasome (prosome, macropain) subunit, alpha type, 6
chr3_-_133380731 18.51 ENST00000260810.5
topoisomerase (DNA) II binding protein 1
chr11_-_71823796 18.32 ENST00000545680.1
ENST00000543587.1
ENST00000538393.1
ENST00000535234.1
ENST00000227618.4
ENST00000535503.1
anaphase promoting complex subunit 15
chrX_+_69509927 17.97 ENST00000374403.3
kinesin family member 4A
chr12_-_121019165 17.69 ENST00000341039.2
ENST00000357500.4
processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
chr5_+_86564739 17.56 ENST00000456692.2
ENST00000512763.1
ENST00000506290.1
RAS p21 protein activator (GTPase activating protein) 1
chr14_+_60715928 17.40 ENST00000395076.4
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr20_-_2451395 17.28 ENST00000339610.6
ENST00000381342.2
ENST00000438552.2
small nuclear ribonucleoprotein polypeptides B and B1
chr22_+_44351419 17.04 ENST00000396202.3
SAMM50 sorting and assembly machinery component
chr5_-_31532160 16.84 ENST00000511367.2
ENST00000513349.1
drosha, ribonuclease type III
chr1_-_193028426 16.76 ENST00000367450.3
ENST00000530098.2
ENST00000367451.4
ENST00000367448.1
ENST00000367449.1
ubiquitin carboxyl-terminal hydrolase L5
chr14_-_21737551 16.68 ENST00000554891.1
ENST00000555883.1
ENST00000553753.1
ENST00000555914.1
ENST00000557336.1
ENST00000555215.1
ENST00000556628.1
ENST00000555137.1
ENST00000556226.1
ENST00000555309.1
ENST00000556142.1
ENST00000554969.1
ENST00000554455.1
ENST00000556513.1
ENST00000557201.1
ENST00000420743.2
ENST00000557768.1
ENST00000553300.1
ENST00000554383.1
ENST00000554539.1
heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr7_+_98923505 16.48 ENST00000432884.2
ENST00000262942.5
actin related protein 2/3 complex, subunit 1A, 41kDa
chr14_+_35761540 16.41 ENST00000261479.4
proteasome (prosome, macropain) subunit, alpha type, 6
chr8_-_117768023 16.11 ENST00000518949.1
ENST00000522453.1
ENST00000521861.1
ENST00000518995.1
eukaryotic translation initiation factor 3, subunit H
chrX_-_153775426 15.42 ENST00000393562.2
glucose-6-phosphate dehydrogenase
chr14_-_21737610 15.42 ENST00000320084.7
ENST00000449098.1
ENST00000336053.6
heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr19_+_58898627 15.31 ENST00000598098.1
ENST00000598495.1
ENST00000196551.3
ENST00000596046.1
ribosomal protein S5
chr4_-_10118348 15.26 ENST00000502702.1
WD repeat domain 1
chr11_-_71823266 15.14 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
anaphase promoting complex subunit 15
chr5_+_31532373 15.03 ENST00000325366.9
ENST00000355907.3
ENST00000507818.2
chromosome 5 open reading frame 22
chr6_+_134274322 15.02 ENST00000367871.1
ENST00000237264.4
TBP-like 1
chr1_+_43124087 14.95 ENST00000304979.3
ENST00000372550.1
ENST00000440068.1
peptidylprolyl isomerase H (cyclophilin H)
chr2_+_187350883 14.85 ENST00000337859.6
zinc finger CCCH-type containing 15
chr22_+_44351301 14.82 ENST00000350028.4
SAMM50 sorting and assembly machinery component
chrX_+_47444613 14.78 ENST00000445623.1
TIMP metallopeptidase inhibitor 1
chr8_-_56987057 14.54 ENST00000518875.1
ribosomal protein S20
chr11_-_71823715 14.51 ENST00000545944.1
ENST00000502597.2
anaphase promoting complex subunit 15
chr2_+_65454926 14.50 ENST00000542850.1
ENST00000377982.4
ARP2 actin-related protein 2 homolog (yeast)
chr1_+_235492300 14.47 ENST00000476121.1
ENST00000497327.1
geranylgeranyl diphosphate synthase 1
chr1_-_19811962 14.20 ENST00000375142.1
ENST00000264202.6
capping protein (actin filament) muscle Z-line, beta
chr1_+_151129135 13.65 ENST00000602841.1
sodium channel modifier 1
chr14_+_67826709 13.61 ENST00000256383.4
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr13_+_27998681 13.44 ENST00000381140.4
general transcription factor IIIA
chr8_-_130951940 13.27 ENST00000522250.1
ENST00000522941.1
ENST00000522746.1
ENST00000520204.1
ENST00000519070.1
ENST00000520254.1
ENST00000519824.2
ENST00000519540.1
family with sequence similarity 49, member B
chr11_+_63754294 13.26 ENST00000543988.1
OTU domain, ubiquitin aldehyde binding 1
chr19_+_19496624 13.26 ENST00000494516.2
ENST00000360315.3
ENST00000252577.5
GATA zinc finger domain containing 2A
chr20_-_34252759 13.22 ENST00000414711.1
ENST00000416778.1
ENST00000397442.1
ENST00000440240.1
ENST00000412056.1
ENST00000352393.4
ENST00000458038.1
ENST00000420363.1
ENST00000434795.1
ENST00000437100.1
ENST00000414664.1
ENST00000359646.1
ENST00000424458.1
ENST00000374104.3
ENST00000374114.3
copine I
RNA binding motif protein 12
chr2_+_187350973 12.99 ENST00000544130.1
zinc finger CCCH-type containing 15
chr3_-_32022733 12.91 ENST00000438237.2
ENST00000396556.2
oxysterol binding protein-like 10
chr2_+_65454863 12.86 ENST00000260641.5
ARP2 actin-related protein 2 homolog (yeast)
chr1_-_235324530 12.80 ENST00000447801.1
ENST00000366606.3
ENST00000429912.1
RNA binding motif protein 34
chr3_+_33840050 12.69 ENST00000457054.2
ENST00000413073.1
programmed cell death 6 interacting protein
chr3_-_196669248 12.44 ENST00000447325.1
nuclear cap binding protein subunit 2, 20kDa
chr7_+_44240520 12.34 ENST00000496112.1
ENST00000223369.2
YKT6 v-SNARE homolog (S. cerevisiae)
chr1_+_84630645 12.14 ENST00000394839.2
protein kinase, cAMP-dependent, catalytic, beta
chr17_+_65714018 12.12 ENST00000581106.1
ENST00000535137.1
nucleolar protein 11
chr1_-_235324772 12.10 ENST00000408888.3
RNA binding motif protein 34
chr7_-_6098770 11.97 ENST00000536084.1
ENST00000446699.1
ENST00000199389.6
eukaryotic translation initiation factor 2-alpha kinase 1
chr6_-_170862322 11.97 ENST00000262193.6
proteasome (prosome, macropain) subunit, beta type, 1
chr17_-_56065484 11.92 ENST00000581208.1
vascular endothelial zinc finger 1
chr11_+_57480046 11.69 ENST00000378312.4
ENST00000278422.4
thioredoxin-related transmembrane protein 2
chr10_+_75504105 11.60 ENST00000535742.1
ENST00000546025.1
ENST00000345254.4
ENST00000540668.1
ENST00000339365.2
ENST00000411652.2
SEC24 family member C
chr19_+_9938562 11.28 ENST00000586895.1
ENST00000358666.3
ENST00000590068.1
ENST00000593087.1
ubiquitin-like 5
chr14_+_24701819 11.16 ENST00000560139.1
ENST00000559910.1
guanosine monophosphate reductase 2
chr7_+_128379346 11.12 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
calumenin
chr13_+_25670268 10.95 ENST00000281589.3
poly(A) binding protein, cytoplasmic 3
chr14_+_24702073 10.93 ENST00000399440.2
guanosine monophosphate reductase 2
chr3_-_196669298 10.86 ENST00000411704.1
ENST00000452404.2
nuclear cap binding protein subunit 2, 20kDa
chr3_+_100428316 10.63 ENST00000479672.1
ENST00000476228.1
ENST00000463568.1
TRK-fused gene
chr20_-_34252847 10.53 ENST00000317619.3
ENST00000397446.1
ENST00000397445.1
ENST00000397443.1
ENST00000430570.1
ENST00000439806.2
ENST00000437340.1
ENST00000435161.1
ENST00000431148.1
copine I
RNA binding motif protein 12
chr19_+_7701985 10.38 ENST00000595950.1
ENST00000441779.2
ENST00000221283.5
ENST00000414284.2
syntaxin binding protein 2
chr17_-_74733404 10.27 ENST00000508921.3
ENST00000583836.1
ENST00000358156.6
ENST00000392485.2
ENST00000359995.5
serine/arginine-rich splicing factor 2
chr1_-_20987851 10.24 ENST00000464364.1
ENST00000602624.2
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr14_-_24701539 10.21 ENST00000534348.1
ENST00000524927.1
ENST00000250495.5
NEDD8-MDP1 readthrough
neural precursor cell expressed, developmentally down-regulated 8
chr7_+_77428149 10.17 ENST00000415251.2
ENST00000275575.7
putative homeodomain transcription factor 2
chr12_-_49961883 10.14 ENST00000553173.1
ENST00000550165.1
ENST00000546244.1
ENST00000343810.4
microspherule protein 1
chr3_+_100428268 10.08 ENST00000240851.4
TRK-fused gene
chr7_+_128379449 10.03 ENST00000479257.1
calumenin
chr2_-_128784846 9.95 ENST00000259235.3
ENST00000357702.5
ENST00000424298.1
Sin3A-associated protein, 130kDa
chr16_+_70557685 9.91 ENST00000302516.5
ENST00000566095.2
ENST00000577085.1
ENST00000567654.1
splicing factor 3b, subunit 3, 130kDa
chr18_+_21032781 9.87 ENST00000339486.3
RIO kinase 3
chr1_-_20987889 9.82 ENST00000415136.2
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr12_+_50135588 9.81 ENST00000423828.1
ENST00000550445.1
transmembrane BAX inhibitor motif containing 6
chr20_+_34129770 9.70 ENST00000348547.2
ENST00000357394.4
ENST00000447986.1
ENST00000279052.6
ENST00000416206.1
ENST00000411577.1
ENST00000413587.1
ERGIC and golgi 3
chr11_+_73498898 9.60 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
mitochondrial ribosomal protein L48
chr14_+_24701628 9.58 ENST00000355299.4
ENST00000559836.1
guanosine monophosphate reductase 2
chr2_+_96931834 9.47 ENST00000488633.1
cytosolic iron-sulfur protein assembly 1
chr8_-_101734170 9.38 ENST00000522387.1
ENST00000518196.1
poly(A) binding protein, cytoplasmic 1
chr19_+_41257084 9.15 ENST00000601393.1
small nuclear ribonucleoprotein polypeptide A
chr6_+_7541808 9.13 ENST00000379802.3
desmoplakin
chr15_+_44092784 9.12 ENST00000458412.1
huntingtin interacting protein K
chr8_-_101965146 9.08 ENST00000395957.2
ENST00000395948.2
ENST00000457309.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr4_-_10118573 8.88 ENST00000382452.2
ENST00000382451.2
WD repeat domain 1
chr22_-_41215291 8.80 ENST00000542412.1
ENST00000544408.1
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr3_+_100428188 8.80 ENST00000418917.2
ENST00000490574.1
TRK-fused gene
chr11_-_58345569 8.76 ENST00000528954.1
ENST00000528489.1
leupaxin
chr20_+_60962143 8.70 ENST00000343986.4
ribosomal protein S21
chr2_+_63816087 8.61 ENST00000409908.1
ENST00000442225.1
ENST00000409476.1
ENST00000436321.1
malate dehydrogenase 1, NAD (soluble)
chr5_-_177580855 8.45 ENST00000514354.1
ENST00000511078.1
NHP2 ribonucleoprotein
chr7_+_93551011 8.40 ENST00000248564.5
guanine nucleotide binding protein (G protein), gamma 11
chr17_-_47755436 8.37 ENST00000505581.1
ENST00000514121.1
ENST00000393328.2
ENST00000509079.1
ENST00000393331.3
ENST00000347630.2
ENST00000504102.1
speckle-type POZ protein
chr3_-_196669371 8.36 ENST00000427641.2
ENST00000321256.5
nuclear cap binding protein subunit 2, 20kDa
chrX_-_131352152 8.15 ENST00000342983.2
RAP2C, member of RAS oncogene family
chr4_-_83812402 7.71 ENST00000395310.2
SEC31 homolog A (S. cerevisiae)
chr4_-_83295103 7.62 ENST00000313899.7
ENST00000352301.4
ENST00000509107.1
ENST00000353341.4
ENST00000541060.1
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr1_-_169337176 7.53 ENST00000472647.1
ENST00000367811.3
NME/NM23 family member 7
chr7_+_100273736 7.50 ENST00000412215.1
ENST00000393924.1
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr4_+_41992489 7.49 ENST00000264451.7
solute carrier family 30 (zinc transporter), member 9
chr12_+_102513950 7.40 ENST00000378128.3
ENST00000327680.2
ENST00000541394.1
ENST00000543784.1
PARP1 binding protein
chrX_-_152486108 7.35 ENST00000356661.5
melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
chr12_+_50794592 7.13 ENST00000293618.8
ENST00000429001.3
ENST00000548174.1
ENST00000548697.1
ENST00000548993.1
ENST00000398473.2
ENST00000522085.1
ENST00000518444.1
ENST00000551886.1
La ribonucleoprotein domain family, member 4
chr8_-_77912431 7.11 ENST00000357039.4
ENST00000522527.1
peroxisomal biogenesis factor 2
chr5_-_177580933 6.97 ENST00000274606.3
NHP2 ribonucleoprotein
chr2_+_178077477 6.87 ENST00000411529.2
ENST00000435711.1
heterogeneous nuclear ribonucleoprotein A3
chr1_+_193028552 6.86 ENST00000400968.2
ENST00000432079.1
TROVE domain family, member 2
chr7_+_77428066 6.76 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
putative homeodomain transcription factor 2
chr6_+_33257427 6.64 ENST00000463584.1
prefoldin subunit 6
chr1_-_20987982 6.55 ENST00000375048.3
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr1_+_24117627 6.50 ENST00000400061.1
lysophospholipase II
chr1_+_84630053 6.37 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
protein kinase, cAMP-dependent, catalytic, beta
chr14_+_89029253 6.37 ENST00000251038.5
ENST00000359301.3
ENST00000302216.8
zinc finger CCCH-type containing 14
chr1_+_39456895 6.37 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
akirin 1
chrX_+_123480194 6.31 ENST00000371139.4
SH2 domain containing 1A
chr4_-_83812248 6.24 ENST00000514326.1
ENST00000505434.1
ENST00000503058.1
ENST00000348405.4
ENST00000505984.1
ENST00000513858.1
ENST00000508479.1
ENST00000443462.2
ENST00000508502.1
ENST00000509142.1
ENST00000432794.1
ENST00000448323.1
ENST00000326950.5
ENST00000311785.7
SEC31 homolog A (S. cerevisiae)
chr7_+_114562172 6.16 ENST00000393486.1
ENST00000257724.3
MyoD family inhibitor domain containing
chr15_-_65810042 6.15 ENST00000321147.6
dipeptidyl-peptidase 8
chr4_-_10118469 6.09 ENST00000499869.2
WD repeat domain 1
chr1_+_24117693 6.07 ENST00000374503.3
ENST00000374502.3
lysophospholipase II
chr3_-_139108475 6.06 ENST00000515006.1
ENST00000513274.1
ENST00000514508.1
ENST00000507777.1
ENST00000512153.1
ENST00000333188.5
coatomer protein complex, subunit beta 2 (beta prime)
chr15_-_65809991 5.93 ENST00000559526.1
ENST00000358939.4
ENST00000560665.1
ENST00000321118.7
ENST00000339244.5
ENST00000300141.6
dipeptidyl-peptidase 8
chr9_+_36190905 5.89 ENST00000345519.5
ENST00000470744.1
ENST00000242285.6
ENST00000466396.1
ENST00000396603.2
clathrin, light chain A
chr11_-_33183006 5.75 ENST00000524827.1
ENST00000323959.4
ENST00000431742.2
cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
chr6_+_43484760 5.75 ENST00000372389.3
ENST00000372344.2
ENST00000304004.3
ENST00000423780.1
polymerase (RNA) I polypeptide C, 30kDa
chr9_+_36190853 5.52 ENST00000433436.2
ENST00000538225.1
ENST00000540080.1
clathrin, light chain A
chr19_-_12780211 5.52 ENST00000597961.1
ENST00000598732.1
ENST00000222190.5
Uncharacterized protein
WD repeat domain 83 opposite strand
chr6_-_116381918 5.43 ENST00000606080.1
fyn-related kinase
chrX_+_123480375 5.28 ENST00000360027.4
SH2 domain containing 1A
chr6_-_31560729 5.27 ENST00000340027.5
ENST00000376073.4
ENST00000376072.3
natural cytotoxicity triggering receptor 3
chr1_-_156698181 5.17 ENST00000313146.6
interferon stimulated exonuclease gene 20kDa-like 2
chr12_+_120972147 5.14 ENST00000325954.4
ENST00000542438.1
ring finger protein 10
chr11_+_111957497 5.13 ENST00000375549.3
ENST00000528182.1
ENST00000528048.1
ENST00000528021.1
ENST00000526592.1
ENST00000525291.1
succinate dehydrogenase complex, subunit D, integral membrane protein
chr16_-_28503357 5.12 ENST00000333496.9
ENST00000561505.1
ENST00000567963.1
ENST00000354630.5
ENST00000355477.5
ENST00000357076.5
ENST00000565688.1
ENST00000359984.7
ceroid-lipofuscinosis, neuronal 3
chr19_-_1650666 5.04 ENST00000588136.1
transcription factor 3
chr14_-_78083112 4.98 ENST00000216484.2
serine palmitoyltransferase, long chain base subunit 2
chr16_-_28503327 4.92 ENST00000535392.1
ENST00000395653.4
ceroid-lipofuscinosis, neuronal 3
chr12_+_54422142 4.92 ENST00000243108.4
homeobox C6
chr16_+_31044812 4.88 ENST00000313843.3
syntaxin 4
chr8_+_15397732 4.75 ENST00000382020.4
ENST00000506802.1
ENST00000509380.1
ENST00000503731.1
tumor suppressor candidate 3
chr11_-_111957451 4.71 ENST00000504148.2
ENST00000541231.1
translocase of inner mitochondrial membrane 8 homolog B (yeast)
chr16_-_28503080 4.58 ENST00000565316.1
ENST00000565778.1
ENST00000357857.9
ENST00000568558.1
ENST00000357806.7
ceroid-lipofuscinosis, neuronal 3
chr22_+_38201114 4.52 ENST00000340857.2
H1 histone family, member 0
chr8_-_56986768 4.49 ENST00000523936.1
ribosomal protein S20
chr6_-_42713792 4.28 ENST00000372876.1
tubulin folding cofactor C
chr20_-_42839378 4.26 ENST00000255174.2
oxidative stress responsive serine-rich 1
chr5_-_892648 4.26 ENST00000483173.1
ENST00000435709.2
bromodomain containing 9
chr20_-_62199427 4.12 ENST00000427522.2
helicase with zinc finger 2, transcriptional coactivator
chr7_-_38948774 4.11 ENST00000395969.2
ENST00000414632.1
ENST00000310301.4
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr7_-_91875109 4.09 ENST00000412043.2
ENST00000430102.1
ENST00000425073.1
ENST00000394503.2
ENST00000454017.1
ENST00000440209.1
ENST00000413688.1
ENST00000452773.1
ENST00000433016.1
ENST00000394505.2
ENST00000422347.1
ENST00000458493.1
ENST00000425919.1
KRIT1, ankyrin repeat containing
chrX_+_123480421 4.05 ENST00000477673.2
SH2 domain containing 1A
chr5_-_114961858 4.02 ENST00000282382.4
ENST00000456936.3
ENST00000408996.4
TMED7-TICAM2 readthrough
transmembrane emp24 protein transport domain containing 7
toll-like receptor adaptor molecule 2
chr12_-_123187890 4.02 ENST00000328880.5
hydroxycarboxylic acid receptor 2
chr12_+_50135351 3.90 ENST00000549445.1
ENST00000550951.1
ENST00000549385.1
ENST00000548713.1
ENST00000548201.1
transmembrane BAX inhibitor motif containing 6
chr7_+_6414128 3.49 ENST00000348035.4
ENST00000356142.4
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
chr1_-_111506562 3.20 ENST00000485275.2
ENST00000369763.4
ligand dependent nuclear receptor interacting factor 1
chr12_+_50135327 3.13 ENST00000549966.1
ENST00000547832.1
ENST00000547187.1
ENST00000548894.1
ENST00000546914.1
ENST00000552699.1
ENST00000267115.5
transmembrane BAX inhibitor motif containing 6
chr10_+_5726764 3.05 ENST00000328090.5
ENST00000496681.1
family with sequence similarity 208, member B
chrX_+_49091920 3.04 ENST00000376227.3
coiled-coil domain containing 22
chr14_+_60716159 2.98 ENST00000325658.3
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr20_-_33999766 2.94 ENST00000349714.5
ENST00000438533.1
ENST00000359226.2
ENST00000374384.2
ENST00000374377.5
ENST00000407996.2
ENST00000424405.1
ENST00000542501.1
ENST00000397554.1
ENST00000540457.1
ENST00000374380.2
ENST00000374385.5
ubiquinol-cytochrome c reductase complex assembly factor 1
chr14_+_89029366 2.92 ENST00000555799.1
ENST00000555755.1
ENST00000393514.5
zinc finger CCCH-type containing 14
chr14_+_22931924 2.87 ENST00000390477.2
T cell receptor delta constant
chr19_+_41256764 2.77 ENST00000243563.3
ENST00000601253.1
ENST00000597353.1
ENST00000599362.1
small nuclear ribonucleoprotein polypeptide A
chr14_+_89029336 2.68 ENST00000556945.1
ENST00000556158.1
ENST00000557607.1
zinc finger CCCH-type containing 14
chr2_+_162016804 2.48 ENST00000392749.2
ENST00000440506.1
TRAF family member-associated NFKB activator

Network of associatons between targets according to the STRING database.

First level regulatory network of SPDEF

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
9.1 27.4 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
8.6 25.8 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188)
8.3 25.0 GO:0090149 mitochondrial membrane fission(GO:0090149)
7.9 31.7 GO:0046833 snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
7.6 22.7 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
7.6 30.2 GO:0016334 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
6.6 32.9 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
5.2 20.9 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
5.1 15.4 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
4.5 13.6 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
4.2 12.7 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
4.2 66.7 GO:0021670 lateral ventricle development(GO:0021670)
3.9 19.7 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
3.8 15.0 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
3.7 18.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
3.7 18.5 GO:0097338 response to clozapine(GO:0097338)
3.7 14.6 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
3.4 20.4 GO:0006499 N-terminal protein myristoylation(GO:0006499)
3.4 10.1 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
3.1 15.4 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
3.0 12.0 GO:0006447 regulation of translational initiation by iron(GO:0006447)
2.9 31.9 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
2.8 16.8 GO:0060701 negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
2.8 35.9 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
2.7 46.0 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
2.6 7.7 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
2.5 7.6 GO:1901355 response to rapamycin(GO:1901355)
2.5 7.6 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
2.5 12.6 GO:0002084 protein depalmitoylation(GO:0002084)
2.3 35.1 GO:0090168 Golgi reassembly(GO:0090168)
2.3 6.8 GO:0043132 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350) NAD transport(GO:0043132)
2.2 13.3 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
2.2 23.7 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
2.1 21.2 GO:0007144 female meiosis I(GO:0007144)
1.9 13.3 GO:1900045 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
1.8 14.8 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
1.8 17.7 GO:0009249 protein lipoylation(GO:0009249)
1.8 5.3 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
1.7 5.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
1.7 16.8 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
1.6 4.9 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
1.3 53.7 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
1.3 9.1 GO:0071896 protein localization to adherens junction(GO:0071896)
1.3 32.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
1.3 25.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
1.3 31.7 GO:0006144 purine nucleobase metabolic process(GO:0006144)
1.3 25.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
1.3 23.9 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
1.2 5.0 GO:1904504 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
1.2 18.0 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
1.2 3.5 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
1.1 8.8 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
1.1 8.7 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
1.1 27.6 GO:0000470 maturation of LSU-rRNA(GO:0000470)
1.0 9.4 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
1.0 58.2 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
1.0 44.3 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
1.0 102.1 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.9 10.2 GO:0045116 protein neddylation(GO:0045116)
0.9 51.2 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.8 4.1 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.8 4.0 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.8 15.6 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.7 33.4 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.7 2.9 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.7 8.6 GO:0006108 malate metabolic process(GO:0006108)
0.7 4.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.7 15.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.7 4.0 GO:0071651 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128) positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.6 22.0 GO:0090383 phagosome acidification(GO:0090383)
0.6 5.1 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.6 5.0 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.6 17.3 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.6 11.4 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.6 62.6 GO:0043488 regulation of mRNA stability(GO:0043488)
0.6 12.9 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.6 9.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.5 10.3 GO:0033197 response to vitamin E(GO:0033197)
0.5 23.2 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.5 1.0 GO:2000644 regulation of receptor catabolic process(GO:2000644)
0.4 23.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.4 29.5 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.4 17.6 GO:0000281 mitotic cytokinesis(GO:0000281)
0.3 15.9 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.3 13.1 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.3 13.7 GO:0008380 RNA splicing(GO:0008380)
0.3 5.8 GO:0006379 mRNA cleavage(GO:0006379)
0.3 1.8 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.3 2.1 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.2 7.1 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.2 7.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.2 16.1 GO:0006446 regulation of translational initiation(GO:0006446)
0.2 3.0 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.2 4.5 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.2 5.5 GO:2000352 negative regulation of endothelial cell apoptotic process(GO:2000352)
0.2 11.9 GO:0001885 endothelial cell development(GO:0001885)
0.2 5.8 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362) termination of RNA polymerase I transcription(GO:0006363)
0.2 6.2 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of viral transcription(GO:0050434)
0.1 4.6 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 9.6 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.1 6.1 GO:1901998 toxin transport(GO:1901998)
0.1 26.8 GO:0050851 antigen receptor-mediated signaling pathway(GO:0050851)
0.1 6.2 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 13.0 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.1 5.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 7.5 GO:0006289 nucleotide-excision repair(GO:0006289)
0.1 21.1 GO:0007596 blood coagulation(GO:0007596)
0.0 0.2 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 1.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 4.7 GO:0007605 sensory perception of sound(GO:0007605)
0.0 11.5 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.7 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 3.6 GO:0051028 mRNA transport(GO:0051028)
0.0 2.2 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
0.0 0.1 GO:0035977 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0 0.1 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.7 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.0 1.5 GO:0006909 phagocytosis(GO:0006909)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
12.0 35.9 GO:0034455 t-UTP complex(GO:0034455)
9.2 55.1 GO:0008537 proteasome activator complex(GO:0008537)
8.3 66.5 GO:0005672 transcription factor TFIIA complex(GO:0005672)
7.9 31.7 GO:0005846 nuclear cap binding complex(GO:0005846)
6.0 30.2 GO:0042643 actomyosin, actin portion(GO:0042643)
5.3 31.7 GO:1902560 GMP reductase complex(GO:1902560)
5.0 25.2 GO:0044530 supraspliceosomal complex(GO:0044530)
4.7 32.9 GO:0071203 WASH complex(GO:0071203)
4.7 41.9 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
4.5 13.6 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
4.5 54.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
4.1 12.3 GO:0097441 basilar dendrite(GO:0097441)
3.7 15.0 GO:0071001 U4/U6 snRNP(GO:0071001)
3.7 76.9 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
3.5 63.4 GO:0034709 methylosome(GO:0034709)
3.3 53.0 GO:0031080 nuclear pore outer ring(GO:0031080)
3.2 22.7 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
2.9 35.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
2.9 31.9 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
2.8 39.7 GO:0001673 male germ cell nucleus(GO:0001673)
2.6 15.4 GO:0090661 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
2.5 17.7 GO:0000172 ribonuclease MRP complex(GO:0000172)
2.4 73.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
2.3 43.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
2.1 10.3 GO:0035061 interchromatin granule(GO:0035061)
2.0 56.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
1.9 21.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
1.8 16.2 GO:0071439 clathrin complex(GO:0071439)
1.6 48.0 GO:0005680 anaphase-promoting complex(GO:0005680)
1.6 9.5 GO:0071817 MMXD complex(GO:0071817)
1.4 42.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
1.3 32.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
1.3 5.1 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
1.3 7.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
1.2 5.0 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
1.2 15.6 GO:0030127 COPII vesicle coat(GO:0030127)
1.2 10.4 GO:0044194 cytolytic granule(GO:0044194)
1.0 16.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
1.0 17.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.9 18.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.9 28.8 GO:0030057 desmosome(GO:0030057)
0.8 27.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.7 12.0 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.7 7.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.7 22.0 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.7 60.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.7 6.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.7 4.6 GO:0016272 prefoldin complex(GO:0016272)
0.6 4.7 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.6 31.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.6 9.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.6 41.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.5 16.8 GO:1902555 endoribonuclease complex(GO:1902555)
0.5 11.9 GO:0005685 U1 snRNP(GO:0005685)
0.5 44.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.4 4.9 GO:0035749 myelin sheath adaxonal region(GO:0035749) lateral loop(GO:0043219)
0.4 18.0 GO:1904115 axon cytoplasm(GO:1904115)
0.4 23.7 GO:0035577 azurophil granule membrane(GO:0035577)
0.3 5.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.3 1.8 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.2 38.6 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 9.6 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 28.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.2 14.6 GO:0005795 Golgi stack(GO:0005795)
0.2 10.9 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.2 8.8 GO:0002102 podosome(GO:0002102)
0.2 1.0 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 1.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 4.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 25.0 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 8.2 GO:0044291 cell-cell contact zone(GO:0044291)
0.1 20.8 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 4.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 0.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 20.9 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 2.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 1.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 68.2 GO:0070062 extracellular exosome(GO:0070062)
0.0 5.8 GO:0005911 cell-cell junction(GO:0005911)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
9.2 27.6 GO:0042134 rRNA primary transcript binding(GO:0042134)
7.9 55.1 GO:0061133 endopeptidase activator activity(GO:0061133)
5.7 22.7 GO:0016748 succinyltransferase activity(GO:0016748)
5.4 54.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
5.3 31.7 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
5.1 15.4 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
4.0 12.0 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
4.0 31.7 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
3.5 17.3 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
3.4 16.8 GO:0032296