GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
SPIC Links Ensembl NCBI GeneCards UniProt	ENSG00000166211.6	Spi-C transcription factor

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr3_-_121379739 Show fit	67.66	ENST00000428394.2 ENST00000314583.3	HCLS1 Links Ensembl NCBI GeneCards UniProt Show fit	hematopoietic cell-specific Lyn substrate 1
chr12_-_15114603 Show fit	58.42	ENST00000228945.4	ARHGDIB Links Ensembl NCBI GeneCards UniProt Show fit	Rho GDP dissociation inhibitor (GDI) beta
chr16_+_30194916 Show fit	55.19	ENST00000570045.1 ENST00000565497.1 ENST00000570244.1	CORO1A Links Ensembl NCBI GeneCards UniProt Show fit	coronin, actin binding protein, 1A
chr1_-_160681593 Show fit	51.35	ENST00000368045.3 ENST00000368046.3	CD48 Links Ensembl NCBI GeneCards UniProt Show fit	CD48 molecule
chr12_-_15114492 Show fit	50.41	ENST00000541546.1	ARHGDIB Links Ensembl NCBI GeneCards UniProt Show fit	Rho GDP dissociation inhibitor (GDI) beta
chr12_+_54892550 Show fit	49.15	ENST00000545638.2	NCKAP1L Links Ensembl NCBI GeneCards UniProt Show fit	NCK-associated protein 1-like
chr13_-_46756351 Show fit	48.29	ENST00000323076.2	LCP1 Links Ensembl NCBI GeneCards UniProt Show fit	lymphocyte cytosolic protein 1 (L-plastin)
chr19_+_49838653 Show fit	47.81	ENST00000598095.1 ENST00000426897.2 ENST00000323906.4 ENST00000535669.2 ENST00000597602.1 ENST00000595660.1	CD37 Links Ensembl NCBI GeneCards UniProt Show fit	CD37 molecule
chr6_+_31554826 Show fit	46.39	ENST00000376089.2 ENST00000396112.2	LST1 Links Ensembl NCBI GeneCards UniProt Show fit	leukocyte specific transcript 1
chr6_-_32557610 Show fit	45.85	ENST00000360004.5	HLA-DRB1 Links Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DR beta 1
chr4_-_103682071 Show fit	44.81	ENST00000505239.1	MANBA Links Ensembl NCBI GeneCards UniProt Show fit	mannosidase, beta A, lysosomal
chr19_-_10446449 Show fit	43.29	ENST00000592439.1	ICAM3 Links Ensembl NCBI GeneCards UniProt Show fit	intercellular adhesion molecule 3
chr13_+_31309645 Show fit	40.77	ENST00000380490.3	ALOX5AP Links Ensembl NCBI GeneCards UniProt Show fit	arachidonate 5-lipoxygenase-activating protein
chr19_-_8642289 Show fit	39.96	ENST00000596675.1 ENST00000338257.8	MYO1F Links Ensembl NCBI GeneCards UniProt Show fit	myosin IF
chr12_+_25205666 Show fit	39.63	ENST00000547044.1	LRMP Links Ensembl NCBI GeneCards UniProt Show fit	lymphoid-restricted membrane protein
chr1_-_31230650 Show fit	38.73	ENST00000294507.3	LAPTM5 Links Ensembl NCBI GeneCards UniProt Show fit	lysosomal protein transmembrane 5
chr12_+_25205568 Show fit	38.24	ENST00000548766.1 ENST00000556887.1	LRMP Links Ensembl NCBI GeneCards UniProt Show fit	lymphoid-restricted membrane protein
chr14_-_23285011 Show fit	37.59	ENST00000397532.3	SLC7A7 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr14_-_23285069 Show fit	37.40	ENST00000554758.1 ENST00000397528.4	SLC7A7 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr1_-_183560011 Show fit	37.18	ENST00000367536.1	NCF2 Links Ensembl NCBI GeneCards UniProt Show fit	neutrophil cytosolic factor 2
chr22_+_23247030 Show fit	36.84	ENST00000390324.2	IGLJ3 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda joining 3
chr22_+_37309662 Show fit	36.05	ENST00000403662.3 ENST00000262825.5	CSF2RB Links Ensembl NCBI GeneCards UniProt Show fit	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr22_+_37257015 Show fit	35.51	ENST00000447071.1 ENST00000248899.6 ENST00000397147.4	NCF4 Links Ensembl NCBI GeneCards UniProt Show fit	neutrophil cytosolic factor 4, 40kDa
chrX_-_107018969 Show fit	35.26	ENST00000372383.4	TSC22D3 Links Ensembl NCBI GeneCards UniProt Show fit	TSC22 domain family, member 3
chr16_-_88717482 Show fit	35.00	ENST00000261623.3	CYBA Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome b-245, alpha polypeptide
chr4_-_74853897 Show fit	34.79	ENST00000296028.3	PPBP Links Ensembl NCBI GeneCards UniProt Show fit	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
chr17_-_29641104 Show fit	33.98	ENST00000577894.1 ENST00000330927.4	EVI2B Links Ensembl NCBI GeneCards UniProt Show fit	ecotropic viral integration site 2B
chr1_+_111415757 Show fit	33.90	ENST00000429072.2 ENST00000271324.5	CD53 Links Ensembl NCBI GeneCards UniProt Show fit	CD53 molecule
chr12_+_7055767 Show fit	32.42	ENST00000447931.2	PTPN6 Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase, non-receptor type 6
chr7_+_74188309 Show fit	32.40	ENST00000289473.4 ENST00000433458.1	NCF1 Links Ensembl NCBI GeneCards UniProt Show fit	neutrophil cytosolic factor 1
chr21_-_46340884 Show fit	31.48	ENST00000302347.5 ENST00000517819.1	ITGB2 Links Ensembl NCBI GeneCards UniProt Show fit	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr6_+_31582961 Show fit	31.45	ENST00000376059.3 ENST00000337917.7	AIF1 Links Ensembl NCBI GeneCards UniProt Show fit	allograft inflammatory factor 1
chr16_+_81812863 Show fit	31.08	ENST00000359376.3	PLCG2 Links Ensembl NCBI GeneCards UniProt Show fit	phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr21_-_46340770 Show fit	30.16	ENST00000397854.3	ITGB2 Links Ensembl NCBI GeneCards UniProt Show fit	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr16_-_88717423 Show fit	29.92	ENST00000568278.1 ENST00000569359.1 ENST00000567174.1	CYBA Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome b-245, alpha polypeptide
chr19_-_10450328 Show fit	29.79	ENST00000160262.5	ICAM3 Links Ensembl NCBI GeneCards UniProt Show fit	intercellular adhesion molecule 3
chr1_-_150738261 Show fit	29.50	ENST00000448301.2 ENST00000368985.3	CTSS Links Ensembl NCBI GeneCards UniProt Show fit	cathepsin S
chr12_+_54891495 Show fit	29.43	ENST00000293373.6	NCKAP1L Links Ensembl NCBI GeneCards UniProt Show fit	NCK-associated protein 1-like
chr19_-_39826639 Show fit	29.23	ENST00000602185.1 ENST00000598034.1 ENST00000601387.1 ENST00000595636.1 ENST00000253054.8 ENST00000594700.1 ENST00000597595.1	GMFG Links Ensembl NCBI GeneCards UniProt Show fit	glia maturation factor, gamma
chr12_+_7055631 Show fit	29.08	ENST00000543115.1 ENST00000399448.1	PTPN6 Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase, non-receptor type 6
chr6_+_31554779 Show fit	28.89	ENST00000376090.2	LST1 Links Ensembl NCBI GeneCards UniProt Show fit	leukocyte specific transcript 1
chr19_-_10450287 Show fit	28.77	ENST00000589261.1 ENST00000590569.1 ENST00000589580.1 ENST00000589249.1	ICAM3 Links Ensembl NCBI GeneCards UniProt Show fit	intercellular adhesion molecule 3
chr2_+_143886877 Show fit	28.67	ENST00000295095.6	ARHGAP15 Links Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 15
chr1_-_25256368 Show fit	28.46	ENST00000308873.6	RUNX3 Links Ensembl NCBI GeneCards UniProt Show fit	runt-related transcription factor 3
chr17_-_29641084 Show fit	27.78	ENST00000544462.1	EVI2B Links Ensembl NCBI GeneCards UniProt Show fit	ecotropic viral integration site 2B
chr19_-_39108568 Show fit	26.95	ENST00000586296.1	MAP4K1 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase kinase 1
chr11_+_1874200 Show fit	24.79	ENST00000311604.3	LSP1 Links Ensembl NCBI GeneCards UniProt Show fit	lymphocyte-specific protein 1
chr10_-_98031310 Show fit	24.73	ENST00000427367.2 ENST00000413476.2	BLNK Links Ensembl NCBI GeneCards UniProt Show fit	B-cell linker
chrX_-_47489244 Show fit	24.21	ENST00000469388.1 ENST00000396992.3 ENST00000377005.2	CFP Links Ensembl NCBI GeneCards UniProt Show fit	complement factor properdin
chr1_-_183559693 Show fit	23.80	ENST00000367535.3 ENST00000413720.1 ENST00000418089.1	NCF2 Links Ensembl NCBI GeneCards UniProt Show fit	neutrophil cytosolic factor 2
chr17_-_20370847 Show fit	23.79	ENST00000423676.3 ENST00000324290.5	LGALS9B Links Ensembl NCBI GeneCards UniProt Show fit	lectin, galactoside-binding, soluble, 9B
chr19_+_13261216 Show fit	23.46	ENST00000587885.1 ENST00000292433.3	IER2 Links Ensembl NCBI GeneCards UniProt Show fit	immediate early response 2
chr5_-_140013275 Show fit	23.24	ENST00000512545.1 ENST00000302014.6 ENST00000401743.2	CD14 Links Ensembl NCBI GeneCards UniProt Show fit	CD14 molecule
chr17_+_72462525 Show fit	22.67	ENST00000360141.3	CD300A Links Ensembl NCBI GeneCards UniProt Show fit	CD300a molecule
chr6_+_31553978 Show fit	22.54	ENST00000376096.1 ENST00000376099.1 ENST00000376110.3	LST1 Links Ensembl NCBI GeneCards UniProt Show fit	leukocyte specific transcript 1
chr11_-_615570 Show fit	22.49	ENST00000525445.1 ENST00000348655.6 ENST00000397566.1	IRF7 Links Ensembl NCBI GeneCards UniProt Show fit	interferon regulatory factor 7
chr19_+_42381337 Show fit	22.18	ENST00000597454.1 ENST00000444740.2	CD79A Links Ensembl NCBI GeneCards UniProt Show fit	CD79a molecule, immunoglobulin-associated alpha
chr11_-_615942 Show fit	22.02	ENST00000397562.3 ENST00000330243.5 ENST00000397570.1 ENST00000397574.2	IRF7 Links Ensembl NCBI GeneCards UniProt Show fit	interferon regulatory factor 7
chr2_+_233925064 Show fit	21.57	ENST00000359570.5 ENST00000538935.1	INPP5D Links Ensembl NCBI GeneCards UniProt Show fit	inositol polyphosphate-5-phosphatase, 145kDa
chr19_-_54784937 Show fit	21.35	ENST00000434421.1 ENST00000314446.5 ENST00000391749.4	LILRB2 Links Ensembl NCBI GeneCards UniProt Show fit	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
chr10_-_98031265 Show fit	21.13	ENST00000224337.5 ENST00000371176.2	BLNK Links Ensembl NCBI GeneCards UniProt Show fit	B-cell linker
chr9_+_134000948 Show fit	20.69	ENST00000359428.5 ENST00000411637.2 ENST00000451030.1	NUP214 Links Ensembl NCBI GeneCards UniProt Show fit	nucleoporin 214kDa
chr16_+_31271274 Show fit	20.68	ENST00000287497.8 ENST00000544665.3	ITGAM Links Ensembl NCBI GeneCards UniProt Show fit	integrin, alpha M (complement component 3 receptor 3 subunit)
chr19_-_39108552 Show fit	20.58	ENST00000591517.1	MAP4K1 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase kinase 1
chr6_+_31554612 Show fit	20.36	ENST00000211921.7	LST1 Links Ensembl NCBI GeneCards UniProt Show fit	leukocyte specific transcript 1
chr3_+_16926441 Show fit	20.24	ENST00000418129.2 ENST00000396755.2	PLCL2 Links Ensembl NCBI GeneCards UniProt Show fit	phospholipase C-like 2
chr6_-_133079022 Show fit	19.97	ENST00000525289.1 ENST00000326499.6	VNN2 Links Ensembl NCBI GeneCards UniProt Show fit	vanin 2
chr5_-_130970723 Show fit	19.85	ENST00000308008.6 ENST00000296859.6 ENST00000507093.1 ENST00000510071.1 ENST00000509018.1 ENST00000307984.5	RAPGEF6 Links Ensembl NCBI GeneCards UniProt Show fit	Rap guanine nucleotide exchange factor (GEF) 6
chr12_-_7656357 Show fit	19.78	ENST00000396620.3 ENST00000432237.2 ENST00000359156.4	CD163 Links Ensembl NCBI GeneCards UniProt Show fit	CD163 molecule
chr7_+_150264365 Show fit	19.36	ENST00000255945.2 ENST00000461940.1	GIMAP4 Links Ensembl NCBI GeneCards UniProt Show fit	GTPase, IMAP family member 4
chr19_-_39108643 Show fit	19.31	ENST00000396857.2	MAP4K1 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase kinase 1
chr14_+_88471468 Show fit	19.17	ENST00000267549.3	GPR65 Links Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 65
chr17_+_34431212 Show fit	19.16	ENST00000394495.1	CCL4 Links Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-C motif) ligand 4
chr4_-_103682145 Show fit	19.14	ENST00000226578.4	MANBA Links Ensembl NCBI GeneCards UniProt Show fit	mannosidase, beta A, lysosomal
chr3_-_50375657 Show fit	18.78	ENST00000395126.3	RASSF1 Links Ensembl NCBI GeneCards UniProt Show fit	Ras association (RalGDS/AF-6) domain family member 1
chr18_-_47813940 Show fit	18.54	ENST00000586837.1 ENST00000412036.2 ENST00000589940.1	CXXC1 Links Ensembl NCBI GeneCards UniProt Show fit	CXXC finger protein 1
chr1_-_150552006 Show fit	18.46	ENST00000307940.3 ENST00000369026.2	MCL1 Links Ensembl NCBI GeneCards UniProt Show fit	myeloid cell leukemia sequence 1 (BCL2-related)
chr12_+_25205446 Show fit	18.33	ENST00000557489.1 ENST00000354454.3 ENST00000536173.1	LRMP Links Ensembl NCBI GeneCards UniProt Show fit	lymphoid-restricted membrane protein
chr17_+_42422662 Show fit	18.30	ENST00000593167.1 ENST00000585512.1 ENST00000591740.1 ENST00000592783.1 ENST00000587387.1 ENST00000588237.1 ENST00000589265.1	GRN Links Ensembl NCBI GeneCards UniProt Show fit	granulin
chr1_+_161475208 Show fit	18.28	ENST00000367972.4 ENST00000271450.6	FCGR2A Links Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgG, low affinity IIa, receptor (CD32)
chr11_-_72463421 Show fit	18.24	ENST00000393609.3	ARAP1 Links Ensembl NCBI GeneCards UniProt Show fit	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr7_-_76829125 Show fit	18.18	ENST00000248598.5	FGL2 Links Ensembl NCBI GeneCards UniProt Show fit	fibrinogen-like 2
chr17_+_72462766 Show fit	17.97	ENST00000392625.3 ENST00000361933.3 ENST00000310828.5	CD300A Links Ensembl NCBI GeneCards UniProt Show fit	CD300a molecule
chr2_-_231084820 Show fit	17.84	ENST00000258382.5 ENST00000338556.3	SP110 Links Ensembl NCBI GeneCards UniProt Show fit	SP110 nuclear body protein
chrX_+_24072833 Show fit	17.53	ENST00000253039.4	EIF2S3 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr5_+_178977546 Show fit	17.52	ENST00000319449.4 ENST00000377001.2	RUFY1 Links Ensembl NCBI GeneCards UniProt Show fit	RUN and FYVE domain containing 1
chr16_-_88851618 Show fit	17.50	ENST00000301015.9	PIEZO1 Links Ensembl NCBI GeneCards UniProt Show fit	piezo-type mechanosensitive ion channel component 1
chr1_-_153518270 Show fit	17.46	ENST00000354332.4 ENST00000368716.4	S100A4 Links Ensembl NCBI GeneCards UniProt Show fit	S100 calcium binding protein A4
chr11_-_60719213 Show fit	17.45	ENST00000227880.3	SLC15A3 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 15 (oligopeptide transporter), member 3
chr12_+_7060432 Show fit	17.43	ENST00000318974.9 ENST00000456013.1	PTPN6 Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase, non-receptor type 6
chr6_+_31553901 Show fit	17.35	ENST00000418507.2 ENST00000438075.2 ENST00000376100.3 ENST00000376111.4	LST1 Links Ensembl NCBI GeneCards UniProt Show fit	leukocyte specific transcript 1
chr5_-_150603679 Show fit	17.35	ENST00000355417.2	CCDC69 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 69
chr4_+_8201091 Show fit	17.31	ENST00000382521.3 ENST00000245105.3 ENST00000457650.2 ENST00000539824.1	SH3TC1 Links Ensembl NCBI GeneCards UniProt Show fit	SH3 domain and tetratricopeptide repeats 1
chr6_+_27114861 Show fit	17.11	ENST00000377459.1	HIST1H2AH Links Ensembl NCBI GeneCards UniProt Show fit	histone cluster 1, H2ah
chrY_+_2709527 Show fit	17.00	ENST00000250784.8	RPS4Y1 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S4, Y-linked 1
chr19_+_859654 Show fit	16.90	ENST00000592860.1	CFD Links Ensembl NCBI GeneCards UniProt Show fit	complement factor D (adipsin)
chr11_+_5710919 Show fit	16.62	ENST00000379965.3 ENST00000425490.1	TRIM22 Links Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 22
chr19_-_36233332 Show fit	16.59	ENST00000592537.1 ENST00000246532.1 ENST00000344990.3 ENST00000588992.1	IGFLR1 Links Ensembl NCBI GeneCards UniProt Show fit	IGF-like family receptor 1
chr19_+_55084438 Show fit	16.48	ENST00000439534.1	LILRA2 Links Ensembl NCBI GeneCards UniProt Show fit	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
chr16_-_21663919 Show fit	16.38	ENST00000569602.1	IGSF6 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin superfamily, member 6
chr16_+_30205225 Show fit	16.36	ENST00000345535.4 ENST00000251303.6	SLX1A Links Ensembl NCBI GeneCards UniProt Show fit	SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)
chr19_+_41903709 Show fit	16.36	ENST00000542943.1 ENST00000457836.2	BCKDHA Links Ensembl NCBI GeneCards UniProt Show fit	branched chain keto acid dehydrogenase E1, alpha polypeptide
chr2_+_68592305 Show fit	16.25	ENST00000234313.7	PLEK Links Ensembl NCBI GeneCards UniProt Show fit	pleckstrin
chr6_+_31554456 Show fit	16.05	ENST00000339530.4	LST1 Links Ensembl NCBI GeneCards UniProt Show fit	leukocyte specific transcript 1
chr16_+_29465822 Show fit	15.99	ENST00000330181.5 ENST00000351581.4	SLX1B Links Ensembl NCBI GeneCards UniProt Show fit	SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chr2_+_182321925 Show fit	15.92	ENST00000339307.4 ENST00000397033.2	ITGA4 Links Ensembl NCBI GeneCards UniProt Show fit	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr19_-_51875894 Show fit	15.90	ENST00000600427.1 ENST00000595217.1 ENST00000221978.5	NKG7 Links Ensembl NCBI GeneCards UniProt Show fit	natural killer cell group 7 sequence
chr22_-_37880543 Show fit	15.86	ENST00000442496.1	MFNG Links Ensembl NCBI GeneCards UniProt Show fit	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr19_+_859425 Show fit	15.75	ENST00000327726.6	CFD Links Ensembl NCBI GeneCards UniProt Show fit	complement factor D (adipsin)
chr10_+_97471508 Show fit	15.71	ENST00000453258.2	ENTPD1 Links Ensembl NCBI GeneCards UniProt Show fit	ectonucleoside triphosphate diphosphohydrolase 1
chr14_-_89883412 Show fit	15.66	ENST00000557258.1	FOXN3 Links Ensembl NCBI GeneCards UniProt Show fit	forkhead box N3
chr19_+_6772710 Show fit	15.57	ENST00000304076.2 ENST00000602142.1 ENST00000596764.1	VAV1 Links Ensembl NCBI GeneCards UniProt Show fit	vav 1 guanine nucleotide exchange factor
chr3_+_151986709 Show fit	15.54	ENST00000495875.2 ENST00000493459.1 ENST00000324210.5 ENST00000459747.1	MBNL1 Links Ensembl NCBI GeneCards UniProt Show fit	muscleblind-like splicing regulator 1
chr20_-_4795747 Show fit	15.48	ENST00000379376.2	RASSF2 Links Ensembl NCBI GeneCards UniProt Show fit	Ras association (RalGDS/AF-6) domain family member 2
chr1_-_161519579 Show fit	15.40	ENST00000426740.1	FCGR3A Links Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr20_+_2821340 Show fit	15.31	ENST00000380445.3 ENST00000380469.3	VPS16 Links Ensembl NCBI GeneCards UniProt Show fit	vacuolar protein sorting 16 homolog (S. cerevisiae)
chr14_+_21423611 Show fit	15.26	ENST00000304625.2	RNASE2 Links Ensembl NCBI GeneCards UniProt Show fit	ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
chr21_-_15918618 Show fit	15.01	ENST00000400564.1 ENST00000400566.1	SAMSN1 Links Ensembl NCBI GeneCards UniProt Show fit	SAM domain, SH3 domain and nuclear localization signals 1
chr19_+_1041212 Show fit	14.83	ENST00000433129.1	ABCA7 Links Ensembl NCBI GeneCards UniProt Show fit	ATP-binding cassette, sub-family A (ABC1), member 7
chr12_-_8218997 Show fit	14.81	ENST00000307637.4	C3AR1 Links Ensembl NCBI GeneCards UniProt Show fit	complement component 3a receptor 1
chr1_+_161632937 Show fit	14.60	ENST00000236937.9 ENST00000367961.4 ENST00000358671.5	FCGR2B Links Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgG, low affinity IIb, receptor (CD32)
chr1_-_161519682 Show fit	14.55	ENST00000367969.3 ENST00000443193.1	FCGR3A Links Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr7_+_100450328 Show fit	14.49	ENST00000540482.1 ENST00000418037.1 ENST00000428758.1 ENST00000275729.3 ENST00000415287.1 ENST00000354161.3 ENST00000416675.1	SLC12A9 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 12, member 9
chr19_+_55128576 Show fit	14.47	ENST00000396331.1	LILRB1 Links Ensembl NCBI GeneCards UniProt Show fit	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr2_-_231084659 Show fit	14.36	ENST00000258381.6 ENST00000358662.4 ENST00000455674.1 ENST00000392048.3	SP110 Links Ensembl NCBI GeneCards UniProt Show fit	SP110 nuclear body protein
chr19_+_55141861 Show fit	14.36	ENST00000396327.3 ENST00000324602.7 ENST00000434867.2	LILRB1 Links Ensembl NCBI GeneCards UniProt Show fit	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr19_-_13213662 Show fit	14.30	ENST00000264824.4	LYL1 Links Ensembl NCBI GeneCards UniProt Show fit	lymphoblastic leukemia derived sequence 1
chr1_+_181057638 Show fit	14.19	ENST00000367577.4	IER5 Links Ensembl NCBI GeneCards UniProt Show fit	immediate early response 5
chr2_-_231084617 Show fit	14.08	ENST00000409815.2	SP110 Links Ensembl NCBI GeneCards UniProt Show fit	SP110 nuclear body protein
chr19_+_35645618 Show fit	13.96	ENST00000392218.2 ENST00000543307.1 ENST00000392219.2 ENST00000541435.2 ENST00000590686.1 ENST00000342879.3 ENST00000588699.1	FXYD5 Links Ensembl NCBI GeneCards UniProt Show fit	FXYD domain containing ion transport regulator 5
chrY_+_15016725 Show fit	13.86	ENST00000336079.3	DDX3Y Links Ensembl NCBI GeneCards UniProt Show fit	DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr15_-_90358048 Show fit	13.62	ENST00000300060.6 ENST00000560137.1	ANPEP Links Ensembl NCBI GeneCards UniProt Show fit	alanyl (membrane) aminopeptidase
chr19_+_55141948 Show fit	13.41	ENST00000396332.4 ENST00000427581.2	LILRB1 Links Ensembl NCBI GeneCards UniProt Show fit	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr7_-_150329421 Show fit	13.38	ENST00000493969.1 ENST00000328902.5	GIMAP6 Links Ensembl NCBI GeneCards UniProt Show fit	GTPase, IMAP family member 6
chr2_+_89998789 Show fit	13.29	ENST00000453166.2	IGKV2D-28 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 2D-28
chr15_-_80263506 Show fit	13.27	ENST00000335661.6	BCL2A1 Links Ensembl NCBI GeneCards UniProt Show fit	BCL2-related protein A1
chr17_-_76123101 Show fit	13.19	ENST00000392467.3	TMC6 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane channel-like 6
chr11_-_64647144 Show fit	12.95	ENST00000359393.2 ENST00000433803.1 ENST00000411683.1	EHD1 Links Ensembl NCBI GeneCards UniProt Show fit	EH-domain containing 1
chr17_-_34625719 Show fit	12.93	ENST00000422211.2 ENST00000542124.1	CCL3L1 Links Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-C motif) ligand 3-like 1
chr17_-_34524157 Show fit	12.69	ENST00000378354.4 ENST00000394484.1	CCL3L3 Links Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-C motif) ligand 3-like 3
chr2_+_89999259 Show fit	12.63	ENST00000558026.1	IGKV2D-28 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 2D-28
chr6_+_31554636 Show fit	12.50	ENST00000433492.1	LST1 Links Ensembl NCBI GeneCards UniProt Show fit	leukocyte specific transcript 1
chr15_+_77287426 Show fit	12.36	ENST00000558012.1 ENST00000267939.5 ENST00000379595.3	PSTPIP1 Links Ensembl NCBI GeneCards UniProt Show fit	proline-serine-threonine phosphatase interacting protein 1
chr14_+_91581011 Show fit	12.31	ENST00000523894.1 ENST00000522322.1 ENST00000523771.1	C14orf159 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 14 open reading frame 159
chr16_-_21663950 Show fit	11.91	ENST00000268389.4	IGSF6 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin superfamily, member 6
chr16_-_15736881 Show fit	11.89	ENST00000540441.2	KIAA0430 Links Ensembl NCBI GeneCards UniProt Show fit	KIAA0430
chr11_+_43380459 Show fit	11.80	ENST00000299240.6 ENST00000039989.4	TTC17 Links Ensembl NCBI GeneCards UniProt Show fit	tetratricopeptide repeat domain 17
chr3_-_49142504 Show fit	11.71	ENST00000306125.6 ENST00000420147.2	QARS Links Ensembl NCBI GeneCards UniProt Show fit	glutaminyl-tRNA synthetase
chr1_+_149230680 Show fit	11.65	ENST00000443018.1	RP11-403I13.5 Links Ensembl NCBI GeneCards UniProt Show fit	RP11-403I13.5
chr18_-_11908329 Show fit	11.58	ENST00000344987.7 ENST00000588103.1 ENST00000588191.1 ENST00000317235.7 ENST00000309976.9 ENST00000588186.1 ENST00000589267.1	MPPE1 Links Ensembl NCBI GeneCards UniProt Show fit	metallophosphoesterase 1
chr3_+_158519654 Show fit	11.15	ENST00000415822.2 ENST00000392813.4 ENST00000264266.8	MFSD1 Links Ensembl NCBI GeneCards UniProt Show fit	major facilitator superfamily domain containing 1
chr19_-_18391708 Show fit	11.10	ENST00000600972.1	JUND Links Ensembl NCBI GeneCards UniProt Show fit	jun D proto-oncogene
chr2_+_202125219 Show fit	11.05	ENST00000323492.7	CASP8 Links Ensembl NCBI GeneCards UniProt Show fit	caspase 8, apoptosis-related cysteine peptidase
chr19_+_46010674 Show fit	10.84	ENST00000245932.6 ENST00000592139.1 ENST00000590603.1	VASP Links Ensembl NCBI GeneCards UniProt Show fit	vasodilator-stimulated phosphoprotein
chr3_+_5229356 Show fit	10.71	ENST00000256497.4	EDEM1 Links Ensembl NCBI GeneCards UniProt Show fit	ER degradation enhancer, mannosidase alpha-like 1
chr17_+_18380051 Show fit	10.70	ENST00000581545.1 ENST00000582333.1 ENST00000328114.6 ENST00000412421.2 ENST00000583322.1 ENST00000584941.1	LGALS9C Links Ensembl NCBI GeneCards UniProt Show fit	lectin, galactoside-binding, soluble, 9C
chr15_-_65282274 Show fit	10.41	ENST00000204566.2	SPG21 Links Ensembl NCBI GeneCards UniProt Show fit	spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr11_+_65408273 Show fit	10.40	ENST00000394227.3	SIPA1 Links Ensembl NCBI GeneCards UniProt Show fit	signal-induced proliferation-associated 1
chr17_+_37356555 Show fit	10.12	ENST00000579374.1	RPL19 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L19
chr1_+_202830876 Show fit	10.09	ENST00000456105.2	RP11-480I12.7 Links Ensembl NCBI GeneCards UniProt Show fit	RP11-480I12.7
chr7_+_108210012 Show fit	9.97	ENST00000249356.3	DNAJB9 Links Ensembl NCBI GeneCards UniProt Show fit	DnaJ (Hsp40) homolog, subfamily B, member 9
chr12_-_6772303 Show fit	9.96	ENST00000396807.4 ENST00000446105.2 ENST00000341550.4	ING4 Links Ensembl NCBI GeneCards UniProt Show fit	inhibitor of growth family, member 4
chr17_+_37356528 Show fit	9.93	ENST00000225430.4	RPL19 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L19
chr17_+_37356586 Show fit	9.91	ENST00000579260.1 ENST00000582193.1	RPL19 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L19
chr14_+_23340822 Show fit	9.90	ENST00000359591.4	LRP10 Links Ensembl NCBI GeneCards UniProt Show fit	low density lipoprotein receptor-related protein 10
chr19_-_19754404 Show fit	9.90	ENST00000587205.1 ENST00000445806.2 ENST00000203556.4	GMIP Links Ensembl NCBI GeneCards UniProt Show fit	GEM interacting protein
chr1_+_158985457 Show fit	9.84	ENST00000567661.1 ENST00000474473.1	IFI16 Links Ensembl NCBI GeneCards UniProt Show fit	interferon, gamma-inducible protein 16
chr18_+_21033239 Show fit	9.77	ENST00000581585.1 ENST00000577501.1	RIOK3 Links Ensembl NCBI GeneCards UniProt Show fit	RIO kinase 3
chr19_+_35645817 Show fit	9.71	ENST00000423817.3	FXYD5 Links Ensembl NCBI GeneCards UniProt Show fit	FXYD domain containing ion transport regulator 5
chr16_+_89627061 Show fit	9.67	ENST00000311528.5 ENST00000563270.1 ENST00000567815.1 ENST00000452368.3 ENST00000467736.1 ENST00000393099.3	RPL13 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L13
chrX_+_11776701 Show fit	9.67	ENST00000476743.1 ENST00000421368.2 ENST00000398527.2	MSL3 Links Ensembl NCBI GeneCards UniProt Show fit	male-specific lethal 3 homolog (Drosophila)
chr6_+_106534192 Show fit	9.66	ENST00000369091.2 ENST00000369096.4	PRDM1 Links Ensembl NCBI GeneCards UniProt Show fit	PR domain containing 1, with ZNF domain
chr19_+_51728316 Show fit	9.57	ENST00000436584.2 ENST00000421133.2 ENST00000391796.3 ENST00000262262.4	CD33 Links Ensembl NCBI GeneCards UniProt Show fit	CD33 molecule
chr2_-_152146385 Show fit	9.52	ENST00000414946.1 ENST00000243346.5	NMI Links Ensembl NCBI GeneCards UniProt Show fit	N-myc (and STAT) interactor
chr19_+_852291 Show fit	9.47	ENST00000263621.1	ELANE Links Ensembl NCBI GeneCards UniProt Show fit	elastase, neutrophil expressed
chr6_+_14117872 Show fit	9.25	ENST00000379153.3	CD83 Links Ensembl NCBI GeneCards UniProt Show fit	CD83 molecule
chr16_-_15736953 Show fit	9.25	ENST00000548025.1 ENST00000551742.1 ENST00000602337.1 ENST00000344181.3 ENST00000396368.3	KIAA0430 Links Ensembl NCBI GeneCards UniProt Show fit	KIAA0430
chr16_-_87799505 Show fit	9.25	ENST00000353170.5 ENST00000561825.1 ENST00000270583.5 ENST00000562261.1 ENST00000347925.5	KLHDC4 Links Ensembl NCBI GeneCards UniProt Show fit	kelch domain containing 4
chr19_-_6481776 Show fit	9.25	ENST00000543576.1 ENST00000590173.1 ENST00000381480.2	DENND1C Links Ensembl NCBI GeneCards UniProt Show fit	DENN/MADD domain containing 1C
chr6_-_99873145 Show fit	9.24	ENST00000369239.5 ENST00000438806.1	PNISR Links Ensembl NCBI GeneCards UniProt Show fit	PNN-interacting serine/arginine-rich protein
chr17_-_34417479 Show fit	9.23	ENST00000225245.5	CCL3 Links Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-C motif) ligand 3
chr19_+_17970693 Show fit	9.21	ENST00000600147.1 ENST00000599898.1	RPL18A Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L18a
chr1_+_6640108 Show fit	9.20	ENST00000377674.4 ENST00000488936.1	ZBTB48 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 48
chr10_-_27149904 Show fit	9.18	ENST00000376166.1 ENST00000376138.3 ENST00000355394.4 ENST00000346832.5 ENST00000376134.3 ENST00000376137.4 ENST00000536334.1 ENST00000490841.2	ABI1 Links Ensembl NCBI GeneCards UniProt Show fit	abl-interactor 1
chr16_+_69796209 Show fit	9.08	ENST00000359154.2 ENST00000561780.1 ENST00000563659.1 ENST00000448661.1	WWP2 Links Ensembl NCBI GeneCards UniProt Show fit	WW domain containing E3 ubiquitin protein ligase 2
chr18_-_61089665 Show fit	9.08	ENST00000238497.5	VPS4B Links Ensembl NCBI GeneCards UniProt Show fit	vacuolar protein sorting 4 homolog B (S. cerevisiae)
chr1_-_153919128 Show fit	8.94	ENST00000361217.4	DENND4B Links Ensembl NCBI GeneCards UniProt Show fit	DENN/MADD domain containing 4B
chr11_-_62380199 Show fit	8.71	ENST00000419857.1 ENST00000394773.2	EML3 Links Ensembl NCBI GeneCards UniProt Show fit	echinoderm microtubule associated protein like 3
chr18_-_53253323 Show fit	8.65	ENST00000540999.1 ENST00000563888.2	TCF4 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr1_-_47069955 Show fit	8.63	ENST00000341183.5 ENST00000496619.1	MKNK1 Links Ensembl NCBI GeneCards UniProt Show fit	MAP kinase interacting serine/threonine kinase 1
chr3_-_49142178 Show fit	8.63	ENST00000452739.1 ENST00000414533.1 ENST00000417025.1	QARS Links Ensembl NCBI GeneCards UniProt Show fit	glutaminyl-tRNA synthetase
chr10_-_121302195 Show fit	8.60	ENST00000369103.2	RGS10 Links Ensembl NCBI GeneCards UniProt Show fit	regulator of G-protein signaling 10
chr17_-_79269067 Show fit	8.57	ENST00000288439.5 ENST00000374759.3	SLC38A10 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 38, member 10
chr7_-_99097863 Show fit	8.53	ENST00000426306.2 ENST00000337673.6	ZNF394 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 394
chr9_+_134065506 Show fit	8.45	ENST00000483497.2	NUP214 Links Ensembl NCBI GeneCards UniProt Show fit	nucleoporin 214kDa
chr9_+_125132803 Show fit	8.42	ENST00000540753.1	PTGS1 Links Ensembl NCBI GeneCards UniProt Show fit	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr11_+_2421718 Show fit	8.37	ENST00000380996.5 ENST00000333256.6 ENST00000380992.1 ENST00000437110.1 ENST00000435795.1	TSSC4 Links Ensembl NCBI GeneCards UniProt Show fit	tumor suppressing subtransferable candidate 4
chr3_+_47324424 Show fit	8.36	ENST00000437353.1 ENST00000232766.5 ENST00000455924.2	KLHL18 Links Ensembl NCBI GeneCards UniProt Show fit	kelch-like family member 18
chr14_-_74417096 Show fit	8.22	ENST00000286544.3	FAM161B Links Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 161, member B
chr2_+_202122703 Show fit	8.15	ENST00000447616.1 ENST00000358485.4	CASP8 Links Ensembl NCBI GeneCards UniProt Show fit	caspase 8, apoptosis-related cysteine peptidase

View svg image
View png image

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
27.2	108.8	GO:0071461	cellular response to redox state(GO:0071461)
19.6	78.6	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) actin polymerization-dependent cell motility(GO:0070358)
18.6	74.3	GO:0033277	abortive mitotic cell cycle(GO:0033277)
17.2	51.7	GO:0002316	follicular B cell differentiation(GO:0002316)
17.0	85.1	GO:0034124	regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
13.8	55.2	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
13.0	64.9	GO:1904845	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
12.5	75.0	GO:1990822	basic amino acid transmembrane transport(GO:1990822)
12.2	36.7	GO:0038043	interleukin-5-mediated signaling pathway(GO:0038043)
10.6	42.2	GO:0035548	gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
9.2	45.8	GO:0002399	MHC class II protein complex assembly(GO:0002399)
7.9	23.7	GO:0046586	regulation of calcium-dependent cell-cell adhesion(GO:0046586)
7.2	21.6	GO:0045658	regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
6.8	20.3	GO:0006425	glutaminyl-tRNA aminoacylation(GO:0006425)
6.7	20.2	GO:0001923	B-1 B cell differentiation(GO:0001923)
6.5	6.5	GO:1904124	microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
6.4	19.2	GO:0052053	modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
6.3	31.5	GO:0014738	regulation of muscle hyperplasia(GO:0014738)
5.8	23.2	GO:0071727	toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
5.3	21.3	GO:0002774	Fc receptor mediated inhibitory signaling pathway(GO:0002774)
5.2	67.7	GO:0045651	positive regulation of macrophage differentiation(GO:0045651)
5.0	35.3	GO:0070236	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
4.9	14.8	GO:1902994	regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
4.8	33.7	GO:0033625	positive regulation of integrin activation(GO:0033625)
4.6	18.2	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)
4.5	95.5	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
4.5	40.6	GO:2001300	lipoxin metabolic process(GO:2001300)
4.4	17.8	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
4.2	12.7	GO:0045404	interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
4.1	28.4	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
4.0	63.9	GO:0009313	oligosaccharide catabolic process(GO:0009313)
4.0	15.9	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
3.8	122.0	GO:0045730	respiratory burst(GO:0045730)
3.6	25.1	GO:0051126	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126)
3.2	22.7	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
3.2	12.7	GO:0036510	trimming of terminal mannose on C branch(GO:0036510)
3.2	9.5	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
3.1	18.5	GO:1903378	positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
3.0	9.1	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611) negative regulation of exosomal secretion(GO:1903542) regulation of centriole elongation(GO:1903722)
3.0	17.9	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
2.9	66.8	GO:0000185	activation of MAPKKK activity(GO:0000185)
2.8	48.3	GO:0071803	positive regulation of podosome assembly(GO:0071803)
2.8	69.6	GO:0006957	complement activation, alternative pathway(GO:0006957)
2.7	16.4	GO:1904431	positive regulation of t-circle formation(GO:1904431)
2.7	10.8	GO:1904379	maintenance of unfolded protein(GO:0036506) protein localization to cytosolic proteasome complex(GO:1904327) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
2.6	25.7	GO:0015939	pantothenate metabolic process(GO:0015939)
2.5	10.0	GO:0043983	histone H4-K12 acetylation(GO:0043983)
2.5	17.3	GO:0097319	fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
2.4	16.8	GO:0051136	regulation of NK T cell differentiation(GO:0051136)
2.4	4.8	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
2.4	14.3	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
2.1	4.2	GO:0060559	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
2.1	10.4	GO:0042631	cellular response to water deprivation(GO:0042631)
2.1	12.4	GO:0052565	response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
2.0	46.8	GO:1901741	positive regulation of myoblast fusion(GO:1901741)
2.0	5.9	GO:0097327	response to antineoplastic agent(GO:0097327)
1.9	17.2	GO:0043152	induction of bacterial agglutination(GO:0043152)
1.9	5.7	GO:0052027	modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
1.9	11.2	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
1.8	5.5	GO:0070902	mitochondrial tRNA pseudouridine synthesis(GO:0070902)
1.8	5.4	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
1.7	153.4	GO:0032945	negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
1.7	10.2	GO:0019060	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
1.7	5.1	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
1.6	8.1	GO:0097029	mature conventional dendritic cell differentiation(GO:0097029)
1.6	6.3	GO:0018094	protein polyglycylation(GO:0018094)
1.5	17.0	GO:0002315	marginal zone B cell differentiation(GO:0002315)
1.5	9.3	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
1.5	6.1	GO:0019086	late viral transcription(GO:0019086)
1.5	3.1	GO:0032661	regulation of interleukin-18 production(GO:0032661)
1.5	44.9	GO:0010447	response to acidic pH(GO:0010447)
1.5	2.9	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
1.4	5.7	GO:0060010	Sertoli cell fate commitment(GO:0060010)
1.4	14.3	GO:0001955	blood vessel maturation(GO:0001955)
1.4	7.1	GO:0019805	tryptophan catabolic process to kynurenine(GO:0019441) quinolinate biosynthetic process(GO:0019805)
1.4	5.6	GO:0034445	regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
1.3	18.5	GO:0034498	early endosome to Golgi transport(GO:0034498)
1.3	15.5	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
1.3	22.8	GO:0035855	megakaryocyte development(GO:0035855)
1.3	1.3	GO:1903094	regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
1.2	14.8	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
1.2	8.6	GO:0043654	recognition of apoptotic cell(GO:0043654)
1.2	6.0	GO:1903026	transcription factor catabolic process(GO:0036369) negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
1.2	10.7	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
1.2	7.1	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) regulation of receptor catabolic process(GO:2000644)
1.2	19.8	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
1.2	15.0	GO:0050869	negative regulation of B cell activation(GO:0050869)
1.1	5.5	GO:0031642	negative regulation of myelination(GO:0031642)
1.1	3.3	GO:0061188	negative regulation of chromatin silencing at rDNA(GO:0061188)
1.1	6.5	GO:0070383	DNA cytosine deamination(GO:0070383)
1.1	5.3	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
1.0	6.2	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
1.0	3.1	GO:0032887	regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
1.0	3.0	GO:0034471	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
1.0	27.3	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
1.0	7.0	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
1.0	8.0	GO:0051601	exocyst localization(GO:0051601)
1.0	15.7	GO:0034656	nucleobase-containing small molecule catabolic process(GO:0034656)
1.0	1.0	GO:0051462	cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462)
1.0	4.8	GO:0090309	positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.9	1.9	GO:0009146	purine nucleoside triphosphate catabolic process(GO:0009146)
0.9	2.8	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.9	6.3	GO:0007000	transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180) nucleolus organization(GO:0007000)
0.9	7.1	GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.9	5.3	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.9	4.3	GO:0035063	nuclear speck organization(GO:0035063)
0.8	2.5	GO:1901668	regulation of superoxide dismutase activity(GO:1901668)
0.8	2.5	GO:0090149	mitochondrial membrane fission(GO:0090149)
0.8	7.3	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.8	3.1	GO:0043321	regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.8	7.6	GO:0002115	store-operated calcium entry(GO:0002115)
0.7	22.1	GO:0034142	toll-like receptor 4 signaling pathway(GO:0034142)
0.7	4.4	GO:0045919	positive regulation of cytolysis(GO:0045919)
0.7	2.1	GO:0097359	UDP-glucosylation(GO:0097359)
0.7	4.8	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.7	3.4	GO:0042989	sequestering of actin monomers(GO:0042989)
0.7	17.6	GO:0006958	complement activation, classical pathway(GO:0006958)
0.7	6.8	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.7	3.4	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.7	7.3	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
0.7	12.4	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.6	5.2	GO:0035897	proteolysis in other organism(GO:0035897)
0.6	6.3	GO:0045023	G0 to G1 transition(GO:0045023)
0.6	24.1	GO:0097421	liver regeneration(GO:0097421)
0.6	4.3	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.6	6.0	GO:1903943	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.6	97.0	GO:0006906	vesicle fusion(GO:0006906)
0.6	8.4	GO:0034447	very-low-density lipoprotein particle clearance(GO:0034447)
0.6	3.5	GO:0060701	negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.6	2.3	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.6	59.9	GO:0030183	B cell differentiation(GO:0030183)
0.6	4.5	GO:1902570	protein localization to nucleolus(GO:1902570)
0.6	91.9	GO:0038096	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.6	5.6	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.6	3.9	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.5	2.2	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.5	1.6	GO:0003352	regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.5	2.1	GO:0045872	positive regulation of rhodopsin gene expression(GO:0045872)
0.5	6.9	GO:0010826	negative regulation of centrosome duplication(GO:0010826)
0.5	2.1	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.5	5.1	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.5	16.4	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.5	9.7	GO:0051255	spindle midzone assembly(GO:0051255)
0.5	1.5	GO:0001300	chronological cell aging(GO:0001300)
0.5	18.0	GO:0006506	GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.5	23.1	GO:0071431	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.5	8.6	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.5	8.4	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.5	6.1	GO:0002227	innate immune response in mucosa(GO:0002227)
0.5	0.9	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.5	3.7	GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.5	7.9	GO:0006622	protein targeting to lysosome(GO:0006622)
0.5	3.7	GO:0040034	regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.5	2.3	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.5	1.8	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.4	4.5	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.4	7.5	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.4	9.2	GO:0010833	telomere maintenance via telomere lengthening(GO:0010833)
0.4	9.2	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.4	3.5	GO:0032790	ribosome disassembly(GO:0032790)
0.4	1.2	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.4	21.9	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.4	36.3	GO:0036498	IRE1-mediated unfolded protein response(GO:0036498)
0.4	0.4	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.4	37.0	GO:0002819	regulation of adaptive immune response(GO:0002819)
0.4	5.4	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.4	9.4	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.4	9.8	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.4	3.3	GO:0008340	determination of adult lifespan(GO:0008340)
0.4	3.9	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.4	65.4	GO:0006909	phagocytosis(GO:0006909)
0.4	1.1	GO:0038163	endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163) positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.4	8.8	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.3	1.4	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.3	1.7	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.3	8.0	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.3	6.3	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.3	3.3	GO:0021562	vestibulocochlear nerve development(GO:0021562)
0.3	1.0	GO:1901873	regulation of post-translational protein modification(GO:1901873)
0.3	1.3	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
0.3	47.4	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.3	6.4	GO:0050855	regulation of B cell receptor signaling pathway(GO:0050855)
0.3	13.6	GO:0043171	peptide catabolic process(GO:0043171)
0.3	12.3	GO:0006536	glutamate metabolic process(GO:0006536)
0.3	5.1	GO:0009435	NAD biosynthetic process(GO:0009435)
0.3	0.9	GO:0019605	benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.3	2.9	GO:0021859	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.3	7.3	GO:0006825	copper ion transport(GO:0006825)
0.3	2.5	GO:0034162	toll-like receptor 9 signaling pathway(GO:0034162)
0.3	4.3	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.3	5.4	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.3	1.9	GO:0010818	T cell chemotaxis(GO:0010818)
0.3	0.8	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241)
0.3	1.8	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.3	3.9	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.3	2.6	GO:0051014	actin filament severing(GO:0051014)
0.3	5.0	GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423)
0.2	5.5	GO:0000132	establishment of mitotic spindle orientation(GO:0000132)
0.2	10.4	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.2	1.0	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.2	2.0	GO:1901673	regulation of mitotic spindle assembly(GO:1901673)
0.2	13.7	GO:0006968	cellular defense response(GO:0006968)
0.2	26.6	GO:1990823	response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.2	1.1	GO:0045063	T-helper 1 cell differentiation(GO:0045063)
0.2	12.8	GO:0051865	protein autoubiquitination(GO:0051865)
0.2	3.3	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.2	3.0	GO:0044803	multi-organism membrane organization(GO:0044803)
0.2	1.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.2	0.8	GO:0001757	somite specification(GO:0001757)
0.2	1.6	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.2	1.2	GO:0061737	leukotriene signaling pathway(GO:0061737)
0.2	5.7	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.2	0.8	GO:2000825	positive regulation of androgen receptor activity(GO:2000825)
0.2	14.3	GO:0038034	signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.2	12.0	GO:0006953	acute-phase response(GO:0006953)
0.2	7.4	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.2	0.6	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857)
0.2	6.2	GO:0070206	protein trimerization(GO:0070206)
0.2	1.3	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.2	0.5	GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.2	5.7	GO:0006298	mismatch repair(GO:0006298)
0.2	0.3	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.2	0.8	GO:0071233	cellular response to leucine(GO:0071233) cellular response to leucine starvation(GO:1990253)
0.2	1.2	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.2	2.6	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1	3.6	GO:0008334	histone mRNA metabolic process(GO:0008334)
0.1	1.3	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.1	3.3	GO:0010667	negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1	4.0	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.1	2.4	GO:2000052	positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.1	1.8	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1	2.1	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.1	8.0	GO:1900034	regulation of cellular response to heat(GO:1900034)
0.1	1.1	GO:0044872	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1	3.7	GO:0015012	heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.1	2.3	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.1	3.6	GO:0001881	receptor recycling(GO:0001881)
0.1	1.1	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1	1.5	GO:0016180	snRNA processing(GO:0016180)
0.1	1.0	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.1	0.6	GO:0006290	pyrimidine dimer repair(GO:0006290) activation of JNKK activity(GO:0007256)
0.1	6.5	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.1	12.8	GO:0071774	response to fibroblast growth factor(GO:0071774)
0.1	5.7	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.1	0.8	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.1	1.4	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.1	12.9	GO:0001837	epithelial to mesenchymal transition(GO:0001837)
0.1	2.8	GO:0007035	vacuolar acidification(GO:0007035)
0.1	11.8	GO:0044782	cilium organization(GO:0044782)
0.1	7.7	GO:0001843	neural tube closure(GO:0001843) tube closure(GO:0060606)
0.1	4.2	GO:0016266	O-glycan processing(GO:0016266)
0.1	2.5	GO:0002076	osteoblast development(GO:0002076)
0.1	13.1	GO:0043484	regulation of RNA splicing(GO:0043484)
0.1	0.3	GO:0015888	thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.1	1.9	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.1	0.8	GO:0070995	NADPH oxidation(GO:0070995)
0.1	15.3	GO:0002250	adaptive immune response(GO:0002250)
0.1	0.8	GO:0035247	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) peptidyl-arginine omega-N-methylation(GO:0035247)
0.1	0.3	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.1	35.5	GO:0002283	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.1	0.7	GO:0017062	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1	0.7	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1	4.5	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.1	1.5	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.1	1.1	GO:0045494	photoreceptor cell maintenance(GO:0045494)
0.1	10.9	GO:0015992	proton transport(GO:0015992)
0.1	1.8	GO:0030199	collagen fibril organization(GO:0030199)
0.1	8.0	GO:0007269	neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.1	19.9	GO:0051056	regulation of small GTPase mediated signal transduction(GO:0051056)
0.1	7.6	GO:1902476	chloride transmembrane transport(GO:1902476)
0.1	4.0	GO:0006306	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.1	1.5	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1	0.1	GO:0046068	cGMP metabolic process(GO:0046068)
0.1	7.5	GO:0007265	Ras protein signal transduction(GO:0007265)
0.1	7.3	GO:0048839	inner ear development(GO:0048839)
0.1	0.7	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.1	0.4	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.2	GO:1902961	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.1	1.6	GO:0036297	interstrand cross-link repair(GO:0036297)
0.1	4.1	GO:0030100	regulation of endocytosis(GO:0030100)
0.1	1.9	GO:0015701	bicarbonate transport(GO:0015701)
0.1	0.5	GO:0035878	nail development(GO:0035878)
0.1	0.4	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.0	0.3	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.0	10.0	GO:0045666	positive regulation of neuron differentiation(GO:0045666)
0.0	1.3	GO:0045732	positive regulation of protein catabolic process(GO:0045732)
0.0	1.4	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.4	GO:0000963	mitochondrial RNA processing(GO:0000963)
0.0	0.2	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	1.1	GO:0045776	negative regulation of blood pressure(GO:0045776)
0.0	0.3	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	2.5	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	1.4	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.3	GO:0097352	autophagosome maturation(GO:0097352) vacuole fusion(GO:0097576)
0.0	0.1	GO:0033143	regulation of intracellular steroid hormone receptor signaling pathway(GO:0033143) regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.0	0.5	GO:0048247	lymphocyte chemotaxis(GO:0048247)
0.0	0.1	GO:1904381	Golgi apparatus mannose trimming(GO:1904381)
0.0	1.1	GO:0009060	aerobic respiration(GO:0009060)
0.0	2.3	GO:0050900	leukocyte migration(GO:0050900)
0.0	0.3	GO:1901655	cellular response to ketone(GO:1901655)
0.0	0.0	GO:0035523	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
16.5	132.0	GO:0032010	phagolysosome(GO:0032010)
16.5	82.3	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
9.7	29.1	GO:1990876	cytoplasmic side of nuclear pore(GO:1990876)
7.5	149.8	GO:0001891	phagocytic cup(GO:0001891)
7.2	101.4	GO:0031209	SCAR complex(GO:0031209)
7.2	78.9	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
5.0	64.9	GO:0043020	NADPH oxidase complex(GO:0043020)
4.5	31.7	GO:0036021	endolysosome lumen(GO:0036021)
4.3	13.0	GO:0020016	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
4.0	20.1	GO:0005602	complement component C1 complex(GO:0005602)
4.0	15.9	GO:0034669	integrin alpha4-beta7 complex(GO:0034669)
3.4	17.0	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
3.3	16.4	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
3.2	22.2	GO:0019815	B cell receptor complex(GO:0019815)
3.2	9.5	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
2.7	10.8	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
2.6	10.2	GO:0036502	Derlin-1-VIMP complex(GO:0036502)
2.5	40.0	GO:0016461	unconventional myosin complex(GO:0016461)
2.3	174.7	GO:0035577	azurophil granule membrane(GO:0035577)
2.2	17.8	GO:0030688	preribosome, small subunit precursor(GO:0030688)
2.2	45.8	GO:0042613	MHC class II protein complex(GO:0042613)
1.9	5.6	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
1.8	5.5	GO:0036194	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
1.8	24.5	GO:0030897	HOPS complex(GO:0030897)
1.7	6.8	GO:0055087	Ski complex(GO:0055087)
1.6	90.5	GO:0001772	immunological synapse(GO:0001772)
1.4	5.7	GO:0043625	delta DNA polymerase complex(GO:0043625)
1.4	18.5	GO:0097136	Bcl-2 family protein complex(GO:0097136)
1.4	25.2	GO:0097342	ripoptosome(GO:0097342)
1.4	18.2	GO:0005577	fibrinogen complex(GO:0005577)
1.4	11.1	GO:0035976	AP1 complex(GO:0035976)
1.4	9.7	GO:0072487	MSL complex(GO:0072487)
1.4	17.6	GO:0048188	Set1C/COMPASS complex(GO:0048188)
1.3	5.1	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
1.3	5.1	GO:0005797	Golgi medial cisterna(GO:0005797)
1.1	23.1	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
1.0	3.1	GO:0031251	PAN complex(GO:0031251)
1.0	3.1	GO:0055028	cortical microtubule(GO:0055028) mitotic spindle astral microtubule(GO:0061673)
1.0	7.1	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
1.0	3.0	GO:0019034	viral replication complex(GO:0019034)
1.0	1.0	GO:0071159	NF-kappaB complex(GO:0071159)
0.9	28.3	GO:0031258	lamellipodium membrane(GO:0031258)
0.9	7.9	GO:0044754	autolysosome(GO:0044754)
0.9	77.3	GO:0070821	tertiary granule membrane(GO:0070821)
0.9	4.3	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.9	4.3	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.8	1.7	GO:0032021	NELF complex(GO:0032021)
0.8	69.8	GO:1904724	tertiary granule lumen(GO:1904724)
0.7	8.9	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.7	8.5	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.7	12.4	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.7	5.4	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.6	5.5	GO:0031616	spindle pole centrosome(GO:0031616)
0.6	8.5	GO:0090543	Flemming body(GO:0090543)
0.6	4.8	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.6	6.4	GO:0042588	zymogen granule(GO:0042588)
0.5	7.6	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.5	55.4	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.5	12.4	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.5	1.5	GO:0072563	endothelial microparticle(GO:0072563)
0.5	2.4	GO:1990393	3M complex(GO:1990393)
0.5	72.7	GO:0031225	anchored component of membrane(GO:0031225)
0.5	4.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.5	46.9	GO:0035578	azurophil granule lumen(GO:0035578)
0.5	3.2	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.4	24.9	GO:0000786	nucleosome(GO:0000786)
0.4	1.3	GO:0002945	cyclin K-CDK13 complex(GO:0002945)
0.4	2.5	GO:1990130	Iml1 complex(GO:1990130)
0.4	118.3	GO:0009897	external side of plasma membrane(GO:0009897)
0.4	29.7	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.4	56.5	GO:0101002	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.4	8.4	GO:0042627	chylomicron(GO:0042627)
0.4	12.3	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.4	0.4	GO:0005953	CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.4	8.8	GO:0034451	centriolar satellite(GO:0034451)
0.4	20.6	GO:0031201	SNARE complex(GO:0031201)
0.3	4.0	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.3	9.3	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.3	9.2	GO:0000781	chromosome, telomeric region(GO:0000781)
0.3	3.7	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.3	1.3	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.3	0.8	GO:0035189	Rb-E2F complex(GO:0035189)
0.2	1.7	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
0.2	5.4	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2	6.7	GO:0030136	clathrin-coated vesicle(GO:0030136)
0.2	11.6	GO:0005801	cis-Golgi network(GO:0005801)
0.2	7.3	GO:0016323	basolateral plasma membrane(GO:0016323)
0.2	4.0	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.2	7.8	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.2	1.6	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.2	5.0	GO:0005921	gap junction(GO:0005921)
0.2	0.8	GO:0030914	STAGA complex(GO:0030914)
0.2	1.3	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2	1.2	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.2	33.0	GO:0098802	plasma membrane receptor complex(GO:0098802)
0.2	2.6	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.2	1.0	GO:0043196	varicosity(GO:0043196)
0.2	1.4	GO:0035102	PRC1 complex(GO:0035102)
0.2	6.2	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2	6.1	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.2	295.3	GO:0005887	integral component of plasma membrane(GO:0005887)
0.2	10.1	GO:0031902	late endosome membrane(GO:0031902)
0.2	8.4	GO:0001750	photoreceptor outer segment(GO:0001750)
0.2	20.7	GO:0031901	early endosome membrane(GO:0031901)
0.2	12.6	GO:0043679	axon terminus(GO:0043679)
0.2	13.2	GO:0010008	endosome membrane(GO:0010008)
0.2	1.5	GO:0032039	integrator complex(GO:0032039)
0.2	3.1	GO:0035580	specific granule lumen(GO:0035580)
0.2	10.9	GO:0005905	clathrin-coated pit(GO:0005905)
0.2	0.8	GO:1990131	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2	20.4	GO:0030139	endocytic vesicle(GO:0030139)
0.2	56.5	GO:0000790	nuclear chromatin(GO:0000790)
0.1	7.9	GO:0072686	mitotic spindle(GO:0072686)
0.1	23.2	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1	1.4	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.1	7.3	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.1	0.4	GO:0000799	nuclear condensin complex(GO:0000799)
0.1	8.5	GO:0015030	Cajal body(GO:0015030)
0.1	12.0	GO:0005814	centriole(GO:0005814)
0.1	2.2	GO:0042383	sarcolemma(GO:0042383)
0.1	11.3	GO:0032587	ruffle membrane(GO:0032587)
0.1	8.0	GO:0043202	lysosomal lumen(GO:0043202)
0.1	3.4	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1	13.1	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1	1.0	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.1	2.1	GO:0051233	spindle midzone(GO:0051233)
0.1	9.7	GO:0030667	secretory granule membrane(GO:0030667)
0.1	2.4	GO:0005861	troponin complex(GO:0005861)
0.1	10.2	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.1	6.1	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.1	3.6	GO:0005802	trans-Golgi network(GO:0005802)
0.1	1.0	GO:0005685	U1 snRNP(GO:0005685)
0.1	2.1	GO:0032040	small-subunit processome(GO:0032040)
0.1	12.3	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.1	2.2	GO:0005819	spindle(GO:0005819)
0.1	0.2	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	10.6	GO:0044454	nuclear chromosome part(GO:0044454)
0.1	0.4	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	1.4	GO:0070069	cytochrome complex(GO:0070069)
0.0	2.8	GO:0030175	filopodium(GO:0030175)
0.0	5.1	GO:0098852	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0	1.4	GO:0097546	ciliary base(GO:0097546)
0.0	4.9	GO:0030133	transport vesicle(GO:0030133)
0.0	4.1	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.8	GO:0032982	myosin filament(GO:0032982)
0.0	7.0	GO:0031965	nuclear membrane(GO:0031965)
0.0	12.9	GO:0000139	Golgi membrane(GO:0000139)
0.0	2.3	GO:0045211	postsynaptic membrane(GO:0045211)
0.0	0.3	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.3	GO:0005903	brush border(GO:0005903)
0.0	2.3	GO:0072562	blood microparticle(GO:0072562)
0.0	1.6	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	5.9	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.1	GO:0032797	SMN complex(GO:0032797)
0.0	3.3	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.3	GO:0031226	intrinsic component of plasma membrane(GO:0031226)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
13.5	40.6	GO:0004464	leukotriene-C4 synthase activity(GO:0004464)
12.9	128.9	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
12.2	36.7	GO:0004914	interleukin-5 receptor activity(GO:0004914)
10.9	108.8	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
10.6	42.2	GO:0030107	HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
8.8	61.6	GO:0030369	ICAM-3 receptor activity(GO:0030369)
7.7	23.2	GO:0016019	peptidoglycan receptor activity(GO:0016019)
7.2	21.6	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
7.0	28.0	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
6.8	75.0	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
6.8	20.3	GO:0004819	glutamine-tRNA ligase activity(GO:0004819)
6.2	18.5	GO:0045322	unmethylated CpG binding(GO:0045322)
5.8	17.4	GO:0022897	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
5.5	16.4	GO:0003826	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
5.3	21.3	GO:0032396	inhibitory MHC class I receptor activity(GO:0032396)
5.2	15.6	GO:0017108	5'-flap endonuclease activity(GO:0017108)
5.2	15.5	GO:0001069	regulatory region RNA binding(GO:0001069)
5.1	20.6	GO:0019770	IgG receptor activity(GO:0019770)
4.9	14.8	GO:0090556	apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
4.0	76.8	GO:0015923	mannosidase activity(GO:0015923)
4.0	20.0	GO:0017159	pantetheine hydrolase activity(GO:0017159)
4.0	15.9	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
3.9	35.3	GO:0043426	MRF binding(GO:0043426)
3.8	19.2	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
3.8	64.9	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
3.7	66.8	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
3.4	55.2	GO:0032036	myosin heavy chain binding(GO:0032036)
3.4	20.7	GO:0001851	complement component C3b binding(GO:0001851)
3.4	48.2	GO:0019864	IgG binding(GO:0019864)
3.1	25.1	GO:0071933	Arp2/3 complex binding(GO:0071933)
3.1	40.6	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
2.9	17.5	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
2.9	77.8	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
2.8	28.4	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
2.7	30.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
2.7	51.6	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
2.5	15.3	GO:0004522	ribonuclease A activity(GO:0004522)
2.5	17.3	GO:0005353	fructose transmembrane transporter activity(GO:0005353)
2.5	12.3	GO:0047820	D-glutamate cyclase activity(GO:0047820)
2.4	4.8	GO:0004832	valine-tRNA ligase activity(GO:0004832)
2.4	14.3	GO:0035800	deubiquitinase activator activity(GO:0035800)
2.2	17.9	GO:0005497	androgen binding(GO:0005497)
2.1	6.3	GO:0001181	transcription factor activity, core RNA polymerase I binding(GO:0001181)
2.1	8.4	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
2.0	32.7	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
2.0	15.9	GO:1990405	protein antigen binding(GO:1990405)
1.8	5.5	GO:0004730	pseudouridylate synthase activity(GO:0004730)
1.8	5.4	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
1.8	51.3	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
1.7	18.5	GO:0051434	BH3 domain binding(GO:0051434)
1.7	21.8	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.6	6.3	GO:0070735	protein-glycine ligase activity(GO:0070735)
1.5	6.1	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
1.5	17.8	GO:0089720	caspase binding(GO:0089720)
1.5	13.3	GO:0051400	BH domain binding(GO:0051400)
1.4	11.6	GO:0034235	GPI anchor binding(GO:0034235)
1.4	5.7	GO:0004594	pantothenate kinase activity(GO:0004594)
1.4	5.6	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
1.4	5.5	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
1.4	6.8	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
1.3	14.8	GO:0004875	complement receptor activity(GO:0004875)
1.3	39.4	GO:0023026	MHC class II protein complex binding(GO:0023026)
1.3	7.9	GO:0050681	steroid hormone receptor binding(GO:0035258) androgen receptor binding(GO:0050681)
1.3	6.5	GO:0047844	deoxycytidine deaminase activity(GO:0047844)
1.3	5.1	GO:0050262	ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
1.3	10.2	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
1.3	1.3	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
1.2	21.0	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
1.2	3.7	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
1.1	15.7	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
1.1	18.2	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
1.1	7.5	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
1.1	5.3	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
1.1	7.4	GO:0004920	interleukin-10 receptor activity(GO:0004920)
1.0	11.2	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
1.0	3.0	GO:0015361	low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.9	19.8	GO:0070300	phosphatidic acid binding(GO:0070300)
0.9	21.6	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.9	1.9	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.9	17.5	GO:0050786	RAGE receptor binding(GO:0050786)
0.9	91.5	GO:0030295	protein kinase activator activity(GO:0030295)
0.9	15.7	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.9	16.2	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.8	29.5	GO:0043236	laminin binding(GO:0043236)
0.8	7.3	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.8	7.1	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.8	6.3	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.8	12.4	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.7	2.2	GO:0016435	rRNA (guanine) methyltransferase activity(GO:0016435)
0.7	5.7	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.7	9.9	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.7	16.9	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.7	2.1	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.7	9.2	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.6	5.1	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.6	10.0	GO:0051787	misfolded protein binding(GO:0051787)
0.6	4.3	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.6	3.5	GO:0060698	endoribonuclease inhibitor activity(GO:0060698)
0.6	7.6	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.6	2.3	GO:0019863	IgE binding(GO:0019863)
0.6	2.3	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.6	7.3	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.6	2.8	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.5	3.3	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.5	1.1	GO:0004947	bradykinin receptor activity(GO:0004947)
0.5	1.1	GO:0042954	lipoprotein transporter activity(GO:0042954)
0.5	1.1	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.5	38.9	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.5	3.1	GO:0051011	microtubule minus-end binding(GO:0051011)
0.5	3.0	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.5	12.4	GO:0004383	guanylate cyclase activity(GO:0004383)
0.5	4.5	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.5	10.4	GO:0042609	CD4 receptor binding(GO:0042609)
0.5	2.0	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.5	37.9	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.5	1.4	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.5	16.6	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.5	2.8	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.5	78.8	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.5	28.8	GO:0019843	rRNA binding(GO:0019843)
0.4	16.8	GO:0005484	SNAP receptor activity(GO:0005484)
0.4	5.1	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.4	6.4	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.4	5.3	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.4	2.3	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.4	18.7	GO:0005044	scavenger receptor activity(GO:0005044)
0.4	4.0	GO:0004438	phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.4	9.7	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.3	2.6	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3	16.2	GO:0017080	sodium channel regulator activity(GO:0017080)
0.3	10.7	GO:0031593	polyubiquitin binding(GO:0031593)
0.3	3.1	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.3	5.4	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.3	4.8	GO:0005537	mannose binding(GO:0005537)
0.3	6.0	GO:0005123	death receptor binding(GO:0005123)
0.3	3.2	GO:0008179	adenylate cyclase binding(GO:0008179)
0.3	12.5	GO:0016279	lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.3	4.5	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.3	15.8	GO:0035064	methylated histone binding(GO:0035064)
0.3	5.2	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.3	6.2	GO:0070403	NAD+ binding(GO:0070403)
0.3	0.5	GO:0004040	amidase activity(GO:0004040)
0.2	7.7	GO:0043015	gamma-tubulin binding(GO:0043015)
0.2	1.9	GO:0004064	arylesterase activity(GO:0004064)
0.2	7.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.2	4.0	GO:0008494	translation activator activity(GO:0008494)
0.2	2.7	GO:0043422	protein kinase B binding(GO:0043422)
0.2	9.9	GO:0001784	phosphotyrosine binding(GO:0001784)
0.2	42.4	GO:0003823	antigen binding(GO:0003823)
0.2	2.8	GO:0035613	RNA stem-loop binding(GO:0035613)
0.2	1.3	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2	1.5	GO:0005534	galactose binding(GO:0005534)
0.2	1.0	GO:0004883	glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.2	27.2	GO:0005178	integrin binding(GO:0005178)
0.2	3.0	GO:0019992	diacylglycerol binding(GO:0019992)
0.2	4.3	GO:0071889	14-3-3 protein binding(GO:0071889)
0.2	4.2	GO:0071949	FAD binding(GO:0071949)
0.2	1.9	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.2	2.4	GO:0031014	troponin T binding(GO:0031014)
0.2	3.4	GO:0001055	RNA polymerase II activity(GO:0001055)
0.2	3.1	GO:0097602	cullin family protein binding(GO:0097602)
0.2	2.2	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2	3.5	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.1	3.5	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.1	43.5	GO:0005096	GTPase activator activity(GO:0005096)
0.1	2.8	GO:0032452	histone demethylase activity(GO:0032452)
0.1	3.5	GO:0003746	translation elongation factor activity(GO:0003746)
0.1	3.2	GO:0036442	hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1	0.5	GO:0035243	protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1	1.9	GO:0017075	syntaxin-1 binding(GO:0017075)
0.1	0.8	GO:0008469	histone-arginine N-methyltransferase activity(GO:0008469) protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1	3.7	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	6.7	GO:0019894	kinesin binding(GO:0019894)
0.1	2.4	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1	3.4	GO:0003785	actin monomer binding(GO:0003785)
0.1	1.2	GO:0097016	L27 domain binding(GO:0097016)
0.1	3.4	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.1	0.9	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1	1.0	GO:0051429	corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1	1.5	GO:0016018	cyclosporin A binding(GO:0016018)
0.1	23.6	GO:0051015	actin filament binding(GO:0051015)
0.1	0.7	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1	0.3	GO:0015234	thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) azole transmembrane transporter activity(GO:1901474)
0.1	20.0	GO:0005516	calmodulin binding(GO:0005516)
0.1	0.9	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.1	2.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	1.4	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1	1.9	GO:0030331	estrogen receptor binding(GO:0030331)
0.1	5.1	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1	0.8	GO:0050321	tau-protein kinase activity(GO:0050321)
0.1	0.3	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
0.1	10.2	GO:0001047	core promoter binding(GO:0001047)
0.1	4.3	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.1	2.5	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1	2.2	GO:0043394	proteoglycan binding(GO:0043394)
0.1	1.1	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1	14.5	GO:0003714	transcription corepressor activity(GO:0003714)
0.1	12.6	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	4.8	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.1	3.3	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1	3.6	GO:0042826	histone deacetylase binding(GO:0042826)
0.1	0.4	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.1	0.9	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	5.5	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	6.8	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.1	1.8	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.1	3.3	GO:0000149	SNARE binding(GO:0000149)
0.1	1.9	GO:0030276	clathrin binding(GO:0030276)
0.1	3.1	GO:0004536	deoxyribonuclease activity(GO:0004536)
0.1	9.2	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.1	1.8	GO:0005109	frizzled binding(GO:0005109)
0.1	3.6	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	1.3	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	17.4	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.2	GO:0001016	transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007) RNA polymerase III regulatory region DNA binding(GO:0001016)
0.0	1.4	GO:0016675	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.2	GO:0001594	trace-amine receptor activity(GO:0001594)
0.0	4.8	GO:0003690	double-stranded DNA binding(GO:0003690)
0.0	6.6	GO:0008083	growth factor activity(GO:0008083)
0.0	0.4	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	2.3	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	16.4	GO:0003700	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0	1.3	GO:0030332	cyclin binding(GO:0030332)
0.0	0.8	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.0	0.1	GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0	6.8	GO:0046982	protein heterodimerization activity(GO:0046982)
0.0	1.0	GO:0005518	collagen binding(GO:0005518)
0.0	0.5	GO:0008009	chemokine activity(GO:0008009)
0.0	0.2	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.3	GO:0051393	alpha-actinin binding(GO:0051393)
0.0	0.6	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.4	GO:0019840	isoprenoid binding(GO:0019840)
0.0	0.4	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.8	199.0	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
2.7	32.0	PID IL5 PATHWAY	IL5-mediated signaling events
2.5	199.4	PID RAC1 PATHWAY	RAC1 signaling pathway
2.4	288.2	PID BCR 5PATHWAY	BCR signaling pathway
2.0	142.6	PID RHOA REG PATHWAY	Regulation of RhoA activity
1.4	54.2	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
1.2	69.6	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
1.1	34.1	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
1.0	25.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
1.0	27.2	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
1.0	29.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.8	7.8	PID EPO PATHWAY	EPO signaling pathway
0.7	15.9	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.6	19.0	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.5	71.4	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.5	26.0	PID IL12 2PATHWAY	IL12-mediated signaling events
0.5	8.5	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.5	18.2	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.4	11.6	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.3	27.5	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.3	13.7	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.3	3.0	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.3	5.4	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.3	6.4	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.3	24.8	PID CMYB PATHWAY	C-MYB transcription factor network
0.2	4.8	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.2	10.2	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2	3.0	PID IGF1 PATHWAY	IGF1 pathway
0.2	7.8	PID IL4 2PATHWAY	IL4-mediated signaling events
0.2	6.9	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.2	7.4	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.2	2.5	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.2	5.7	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.2	7.1	PID MTOR 4PATHWAY	mTOR signaling pathway
0.1	2.3	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	3.0	PID RAS PATHWAY	Regulation of Ras family activation
0.1	1.9	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.1	0.9	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.1	4.0	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	9.1	PID P53 REGULATION PATHWAY	p53 pathway
0.1	21.8	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	1.0	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.1	3.3	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.1	39.3	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.1	2.4	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.1	4.0	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.1	3.9	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.1	4.0	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.1	1.3	PID EPHB FWD PATHWAY	EPHB forward signaling
0.1	2.9	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.1	1.2	PID INSULIN PATHWAY	Insulin Pathway
0.1	1.5	PID ALK1 PATHWAY	ALK1 signaling events
0.1	1.5	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	1.1	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.7	PID BARD1 PATHWAY	BARD1 signaling events
0.0	1.2	PID NOTCH PATHWAY	Notch signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.8	29.5	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
3.9	51.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
3.9	121.2	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
3.4	147.4	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
3.2	279.2	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
2.7	51.1	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
2.4	120.3	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
2.1	25.3	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
1.7	70.9	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
1.3	81.6	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
1.2	14.8	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
1.1	36.7	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.9	162.4	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.9	7.1	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.9	3.4	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.8	23.8	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.8	17.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.8	17.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.8	29.9	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.7	17.1	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.7	14.8	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.7	17.4	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.7	12.3	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.7	7.2	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.7	12.4	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.6	7.8	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.6	46.5	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.6	16.4	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.6	14.8	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.6	45.8	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.5	85.4	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.5	23.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.4	7.1	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.4	5.0	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.4	5.9	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.3	6.2	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.3	7.3	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.3	10.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.3	3.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.3	4.4	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.3	8.6	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.3	6.0	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.3	3.9	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.3	3.0	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.3	11.7	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.3	4.5	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.2	2.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.2	3.7	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.2	3.6	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2	3.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2	3.4	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.2	14.4	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.1	1.9	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	2.4	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.1	6.2	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.1	1.0	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	2.9	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.1	3.4	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.1	3.8	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.1	5.5	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.1	2.6	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.1	3.2	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.1	4.0	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.1	1.8	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.1	1.6	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	7.9	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.1	0.7	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	11.5	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.1	1.7	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	2.4	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.1	2.1	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	6.7	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	5.1	REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS	Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0	0.7	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	2.1	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	3.9	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	1.6	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.5	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.8	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels