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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for SREBF1_TFE3

Z-value: 1.39

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Transcription factors associated with SREBF1_TFE3

Gene Symbol Gene ID Gene Info
SREBF1
ENSG00000072310.12 sterol regulatory element binding transcription factor 1
TFE3
ENSG00000068323.12 transcription factor binding to IGHM enhancer 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFE3hg19_v2_chrX_-_48901012_489010500.432.2e-11Click!
SREBF1hg19_v2_chr17_-_17740287_17740316-0.082.4e-01Click!

Activity profile of SREBF1_TFE3 motif

Sorted Z-values of SREBF1_TFE3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_10764509 58.79 ENST00000591501.1
ILF3-AS1
ILF3 antisense RNA 1 (head to head)
chr19_+_40854559 45.16 ENST00000598962.1
ENST00000409419.1
ENST00000409587.1
ENST00000602131.1
ENST00000409735.4
ENST00000600948.1
ENST00000356508.5
ENST00000596682.1
ENST00000594908.1
PLD3
phospholipase D family, member 3
chr13_+_113951607 44.90 ENST00000397181.3
LAMP1
lysosomal-associated membrane protein 1
chr19_-_48018203 41.50 ENST00000595227.1
ENST00000593761.1
ENST00000263354.3
NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr13_+_113951532 37.23 ENST00000332556.4
LAMP1
lysosomal-associated membrane protein 1
chr11_-_1785139 36.82 ENST00000236671.2
CTSD
cathepsin D
chr1_-_11866034 33.43 ENST00000376590.3
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr1_+_11866207 33.05 ENST00000312413.6
ENST00000346436.6
CLCN6
chloride channel, voltage-sensitive 6
chr17_+_78075361 32.12 ENST00000577106.1
ENST00000390015.3
GAA
glucosidase, alpha; acid
chr17_+_78075498 28.73 ENST00000302262.3
GAA
glucosidase, alpha; acid
chr16_-_67514982 28.55 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
ATP6V0D1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr1_-_11865982 27.86 ENST00000418034.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr20_+_44519948 27.66 ENST00000354880.5
ENST00000191018.5
CTSA
cathepsin A
chr1_-_154193009 27.11 ENST00000368518.1
ENST00000368519.1
ENST00000368521.5
C1orf43
chromosome 1 open reading frame 43
chr20_+_44520009 25.97 ENST00000607482.1
ENST00000372459.2
CTSA
cathepsin A
chr14_-_81687575 25.28 ENST00000434192.2
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr14_-_81687197 25.11 ENST00000553612.1
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr1_+_11866270 24.97 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
CLCN6
chloride channel, voltage-sensitive 6
chr1_-_241520525 24.32 ENST00000366565.1
RGS7
regulator of G-protein signaling 7
chrX_+_103031758 22.37 ENST00000303958.2
ENST00000361621.2
PLP1
proteolipid protein 1
chr17_-_73851285 21.89 ENST00000589642.1
ENST00000593002.1
ENST00000590221.1
ENST00000344296.4
ENST00000587374.1
ENST00000585462.1
ENST00000433525.2
ENST00000254806.3
WBP2
WW domain binding protein 2
chr12_-_122751002 21.78 ENST00000267199.4
VPS33A
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr16_+_85061367 20.36 ENST00000538274.1
ENST00000258180.3
KIAA0513
KIAA0513
chr15_-_72668185 20.30 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
HEXA
hexosaminidase A (alpha polypeptide)
chr22_-_36903069 20.15 ENST00000216187.6
ENST00000423980.1
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr22_-_36903101 19.50 ENST00000397224.4
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr8_-_17941575 19.31 ENST00000417108.2
ASAH1
N-acylsphingosine amidohydrolase (acid ceramidase) 1
chr4_+_76439665 19.30 ENST00000508105.1
ENST00000311638.3
ENST00000380837.3
ENST00000507556.1
ENST00000504190.1
ENST00000507885.1
ENST00000502620.1
ENST00000514480.1
THAP6
THAP domain containing 6
chr15_-_73925651 18.89 ENST00000545878.1
ENST00000287226.8
ENST00000345330.4
NPTN
neuroplastin
chr1_-_154531095 18.51 ENST00000292211.4
UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr19_+_7587491 18.27 ENST00000264079.6
MCOLN1
mucolipin 1
chr16_-_5083589 17.73 ENST00000563578.1
ENST00000562346.2
NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr17_-_18218237 17.34 ENST00000542570.1
TOP3A
topoisomerase (DNA) III alpha
chr17_+_42422662 17.31 ENST00000593167.1
ENST00000585512.1
ENST00000591740.1
ENST00000592783.1
ENST00000587387.1
ENST00000588237.1
ENST00000589265.1
GRN
granulin
chr17_-_6915646 17.08 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
AC027763.2
Uncharacterized protein
chr12_-_91539918 16.69 ENST00000548218.1
DCN
decorin
chr16_-_5083917 16.58 ENST00000312251.3
ENST00000381955.3
NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chrX_+_102469997 16.24 ENST00000372695.5
ENST00000372691.3
BEX4
brain expressed, X-linked 4
chr8_-_120685608 15.82 ENST00000427067.2
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr8_-_54755789 15.77 ENST00000359530.2
ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr2_+_220042933 15.63 ENST00000430297.2
FAM134A
family with sequence similarity 134, member A
chr17_-_7137582 15.62 ENST00000575756.1
ENST00000575458.1
DVL2
dishevelled segment polarity protein 2
chrX_+_101380642 15.57 ENST00000372780.1
ENST00000329035.2
TCEAL2
transcription elongation factor A (SII)-like 2
chr17_+_42422637 15.42 ENST00000053867.3
ENST00000588143.1
GRN
granulin
chr9_-_131709858 15.21 ENST00000372586.3
DOLK
dolichol kinase
chr6_-_33385902 14.86 ENST00000374500.5
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr1_-_241520385 14.82 ENST00000366564.1
RGS7
regulator of G-protein signaling 7
chr9_+_74526384 14.54 ENST00000334731.2
ENST00000377031.3
C9orf85
chromosome 9 open reading frame 85
chr9_+_115913222 14.44 ENST00000259392.3
SLC31A2
solute carrier family 31 (copper transporter), member 2
chr8_-_54755459 14.25 ENST00000524234.1
ENST00000521275.1
ENST00000396774.2
ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chrX_+_102631844 13.97 ENST00000372634.1
ENST00000299872.7
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr15_-_83316087 13.96 ENST00000568757.1
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr20_-_36156125 13.93 ENST00000397135.1
ENST00000397137.1
BLCAP
bladder cancer associated protein
chrX_+_102631248 13.83 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr16_-_1525016 13.72 ENST00000262318.8
ENST00000448525.1
CLCN7
chloride channel, voltage-sensitive 7
chr1_-_21995794 13.69 ENST00000542643.2
ENST00000374765.4
ENST00000317967.7
RAP1GAP
RAP1 GTPase activating protein
chr12_+_12878829 13.41 ENST00000326765.6
APOLD1
apolipoprotein L domain containing 1
chr15_+_44084040 13.33 ENST00000249786.4
SERF2
small EDRK-rich factor 2
chr18_-_21977748 13.31 ENST00000399441.4
ENST00000319481.3
OSBPL1A
oxysterol binding protein-like 1A
chr6_-_33385870 13.28 ENST00000488034.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr5_-_172198190 13.23 ENST00000239223.3
DUSP1
dual specificity phosphatase 1
chr1_+_44440575 13.18 ENST00000532642.1
ENST00000236067.4
ENST00000471859.2
ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr17_+_3539998 12.96 ENST00000452111.1
ENST00000574776.1
ENST00000441220.2
ENST00000414524.2
CTNS
cystinosin, lysosomal cystine transporter
chr11_-_66336060 12.93 ENST00000310325.5
CTSF
cathepsin F
chr11_-_116968987 12.92 ENST00000434315.2
ENST00000292055.4
ENST00000375288.1
ENST00000542607.1
ENST00000445177.1
ENST00000375300.1
ENST00000446921.2
SIK3
SIK family kinase 3
chr1_+_183605200 12.81 ENST00000304685.4
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr17_-_73975444 12.74 ENST00000293217.5
ENST00000537812.1
ACOX1
acyl-CoA oxidase 1, palmitoyl
chr9_+_17579084 12.70 ENST00000380607.4
SH3GL2
SH3-domain GRB2-like 2
chr4_+_128651530 12.64 ENST00000281154.4
SLC25A31
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr8_-_120605194 12.53 ENST00000522167.1
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr3_+_5020801 12.43 ENST00000256495.3
BHLHE40
basic helix-loop-helix family, member e40
chr15_-_72668805 12.05 ENST00000268097.5
HEXA
hexosaminidase A (alpha polypeptide)
chr10_-_73611046 12.01 ENST00000394934.1
ENST00000394936.3
PSAP
prosaposin
chr8_-_27457494 11.79 ENST00000521770.1
CLU
clusterin
chr6_-_33385655 11.66 ENST00000440279.3
ENST00000607266.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr9_-_79307096 11.66 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
PRUNE2
prune homolog 2 (Drosophila)
chr14_-_74551096 11.60 ENST00000350259.4
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr17_-_66951474 11.53 ENST00000269080.2
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr17_+_3539744 11.41 ENST00000046640.3
ENST00000381870.3
CTNS
cystinosin, lysosomal cystine transporter
chr5_-_42811986 11.30 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr20_-_36156293 11.17 ENST00000373537.2
ENST00000414542.2
BLCAP
bladder cancer associated protein
chr7_+_116593292 11.16 ENST00000393446.2
ENST00000265437.5
ENST00000393451.3
ST7
suppression of tumorigenicity 7
chr16_-_88923285 10.89 ENST00000542788.1
ENST00000569433.1
ENST00000268695.5
ENST00000568311.1
GALNS
galactosamine (N-acetyl)-6-sulfate sulfatase
chr16_+_2563871 10.89 ENST00000330398.4
ENST00000568562.1
ENST00000569317.1
ATP6V0C
ATP6C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
Uncharacterized protein
chr19_+_5681011 10.86 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
HSD11B1L
hydroxysteroid (11-beta) dehydrogenase 1-like
chr5_+_94890778 10.79 ENST00000380009.4
ARSK
arylsulfatase family, member K
chr22_-_39636914 10.71 ENST00000381551.4
PDGFB
platelet-derived growth factor beta polypeptide
chr18_+_54318616 10.68 ENST00000254442.3
WDR7
WD repeat domain 7
chr9_+_706842 10.67 ENST00000382293.3
KANK1
KN motif and ankyrin repeat domains 1
chr6_-_33385854 10.67 ENST00000488478.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chrX_-_13835461 10.56 ENST00000316715.4
ENST00000356942.5
GPM6B
glycoprotein M6B
chr6_+_42018251 10.53 ENST00000372978.3
ENST00000494547.1
ENST00000456846.2
ENST00000372982.4
ENST00000472818.1
ENST00000372977.3
TAF8
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr12_+_54332535 10.51 ENST00000243056.3
HOXC13
homeobox C13
chr7_+_23286182 10.40 ENST00000258733.4
ENST00000381990.2
ENST00000409458.3
ENST00000539136.1
ENST00000453162.2
GPNMB
glycoprotein (transmembrane) nmb
chr6_-_33385823 10.36 ENST00000494751.1
ENST00000374496.3
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr21_-_35987438 10.18 ENST00000313806.4
RCAN1
regulator of calcineurin 1
chr6_+_127587755 10.14 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
RNF146
ring finger protein 146
chr3_-_49395705 10.10 ENST00000419349.1
GPX1
glutathione peroxidase 1
chr17_-_17875688 10.04 ENST00000379504.3
ENST00000318094.10
ENST00000540946.1
ENST00000542206.1
ENST00000395739.4
ENST00000581396.1
ENST00000535933.1
ENST00000579586.1
TOM1L2
target of myb1-like 2 (chicken)
chr3_-_49395892 9.96 ENST00000419783.1
GPX1
glutathione peroxidase 1
chr16_+_84178874 9.95 ENST00000378553.5
DNAAF1
dynein, axonemal, assembly factor 1
chrX_-_34675391 9.92 ENST00000275954.3
TMEM47
transmembrane protein 47
chr11_+_65479702 9.90 ENST00000530446.1
ENST00000534104.1
ENST00000530605.1
ENST00000528198.1
ENST00000531880.1
ENST00000534650.1
KAT5
K(lysine) acetyltransferase 5
chr5_+_150404904 9.87 ENST00000521632.1
GPX3
glutathione peroxidase 3 (plasma)
chr22_+_35695793 9.85 ENST00000456128.1
ENST00000449058.2
ENST00000411850.1
ENST00000425375.1
ENST00000436462.2
ENST00000382034.5
TOM1
target of myb1 (chicken)
chr9_-_123476719 9.84 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr3_+_51428704 9.75 ENST00000323686.4
RBM15B
RNA binding motif protein 15B
chr16_+_8806800 9.68 ENST00000561870.1
ENST00000396600.2
ABAT
4-aminobutyrate aminotransferase
chr7_+_99699280 9.64 ENST00000421755.1
AP4M1
adaptor-related protein complex 4, mu 1 subunit
chr9_-_123476612 9.60 ENST00000426959.1
MEGF9
multiple EGF-like-domains 9
chrX_-_100914781 9.52 ENST00000431597.1
ENST00000458024.1
ENST00000413506.1
ENST00000440675.1
ENST00000328766.5
ENST00000356824.4
ARMCX2
armadillo repeat containing, X-linked 2
chr7_+_45613958 9.44 ENST00000297323.7
ADCY1
adenylate cyclase 1 (brain)
chrX_-_102319092 9.42 ENST00000372728.3
BEX1
brain expressed, X-linked 1
chr15_-_83316254 9.38 ENST00000567678.1
ENST00000450751.2
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr5_-_133706695 9.28 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
CDKL3
cyclin-dependent kinase-like 3
chr17_-_18218270 9.24 ENST00000321105.5
TOP3A
topoisomerase (DNA) III alpha
chr10_-_118764862 9.19 ENST00000260777.10
KIAA1598
KIAA1598
chrX_+_70586140 9.11 ENST00000276072.3
TAF1
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
chr7_+_116593433 9.11 ENST00000323984.3
ENST00000393449.1
ST7
suppression of tumorigenicity 7
chr12_-_114404111 9.07 ENST00000545145.2
ENST00000392561.3
ENST00000261741.5
RBM19
RNA binding motif protein 19
chr6_+_148663729 9.03 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1
chr12_+_6644443 9.01 ENST00000396858.1
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr14_-_74551172 8.99 ENST00000553458.1
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr14_+_96505659 8.87 ENST00000555004.1
C14orf132
chromosome 14 open reading frame 132
chr10_-_118765081 8.86 ENST00000392903.2
ENST00000355371.4
KIAA1598
KIAA1598
chr3_+_184032419 8.83 ENST00000352767.3
ENST00000427141.2
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr11_+_118938485 8.83 ENST00000300793.6
VPS11
vacuolar protein sorting 11 homolog (S. cerevisiae)
chr19_-_11688447 8.83 ENST00000590420.1
ACP5
acid phosphatase 5, tartrate resistant
chr17_+_73975292 8.78 ENST00000397640.1
ENST00000416485.1
ENST00000588202.1
ENST00000590676.1
ENST00000586891.1
TEN1
TEN1 CST complex subunit
chr3_+_128444965 8.72 ENST00000265062.3
RAB7A
RAB7A, member RAS oncogene family
chr12_-_65153175 8.66 ENST00000543646.1
ENST00000542058.1
ENST00000258145.3
GNS
glucosamine (N-acetyl)-6-sulfatase
chr16_+_6533380 8.65 ENST00000552089.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr10_-_50970322 8.65 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr6_+_123110465 8.56 ENST00000539041.1
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr8_-_22089845 8.55 ENST00000454243.2
PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr19_-_11688500 8.47 ENST00000433365.2
ACP5
acid phosphatase 5, tartrate resistant
chr6_-_84937314 8.46 ENST00000257766.4
ENST00000403245.3
KIAA1009
KIAA1009
chr19_+_36359341 8.45 ENST00000221891.4
APLP1
amyloid beta (A4) precursor-like protein 1
chr15_+_44084503 8.26 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
SERF2
small EDRK-rich factor 2
chr19_-_14606900 8.21 ENST00000393029.3
ENST00000393028.1
ENST00000393033.4
ENST00000345425.2
ENST00000586027.1
ENST00000591349.1
ENST00000587210.1
GIPC1
GIPC PDZ domain containing family, member 1
chr8_-_22089533 8.16 ENST00000321613.3
PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr2_-_220042825 8.12 ENST00000409789.1
CNPPD1
cyclin Pas1/PHO80 domain containing 1
chr18_+_56530794 8.04 ENST00000590285.1
ENST00000586085.1
ENST00000589288.1
ZNF532
zinc finger protein 532
chr16_-_30134524 8.03 ENST00000395202.1
ENST00000395199.3
ENST00000263025.4
ENST00000322266.5
ENST00000403394.1
MAPK3
mitogen-activated protein kinase 3
chr2_-_175870085 8.01 ENST00000409156.3
CHN1
chimerin 1
chr9_-_90589402 8.00 ENST00000375871.4
ENST00000605159.1
ENST00000336654.5
CDK20
cyclin-dependent kinase 20
chr1_+_154193325 7.93 ENST00000428931.1
ENST00000441890.1
ENST00000271877.7
ENST00000412596.1
ENST00000368504.1
ENST00000437652.1
UBAP2L
ubiquitin associated protein 2-like
chr17_+_17876127 7.91 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
LRRC48
leucine rich repeat containing 48
chr6_-_84418860 7.89 ENST00000521743.1
SNAP91
synaptosomal-associated protein, 91kDa
chr6_+_123110302 7.88 ENST00000368440.4
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr13_+_42846272 7.85 ENST00000025301.2
AKAP11
A kinase (PRKA) anchor protein 11
chr10_-_118502070 7.84 ENST00000369209.3
HSPA12A
heat shock 70kDa protein 12A
chr1_-_207119738 7.84 ENST00000356495.4
PIGR
polymeric immunoglobulin receptor
chr16_-_4897266 7.80 ENST00000591451.1
ENST00000436648.5
ENST00000381983.3
ENST00000588297.1
ENST00000321919.9
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr2_-_176866978 7.79 ENST00000392540.2
ENST00000409660.1
ENST00000544803.1
ENST00000272748.4
KIAA1715
KIAA1715
chr20_-_44540686 7.76 ENST00000477313.1
ENST00000542937.1
ENST00000372431.3
ENST00000354050.4
ENST00000420868.2
PLTP
phospholipid transfer protein
chr12_-_121342170 7.66 ENST00000353487.2
SPPL3
signal peptide peptidase like 3
chr19_-_49137790 7.63 ENST00000599385.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr6_-_84418841 7.60 ENST00000369694.2
ENST00000195649.6
SNAP91
synaptosomal-associated protein, 91kDa
chr16_+_2098003 7.57 ENST00000439673.2
ENST00000350773.4
TSC2
tuberous sclerosis 2
chrX_+_102840408 7.54 ENST00000468024.1
ENST00000472484.1
ENST00000415568.2
ENST00000490644.1
ENST00000459722.1
ENST00000472745.1
ENST00000494801.1
ENST00000434216.2
ENST00000425011.1
TCEAL4
transcription elongation factor A (SII)-like 4
chr12_+_6833237 7.54 ENST00000229251.3
ENST00000539735.1
ENST00000538410.1
COPS7A
COP9 signalosome subunit 7A
chr6_-_46293378 7.42 ENST00000330430.6
RCAN2
regulator of calcineurin 2
chr11_+_65479462 7.41 ENST00000377046.3
ENST00000352980.4
ENST00000341318.4
KAT5
K(lysine) acetyltransferase 5
chr16_+_2564254 7.36 ENST00000565223.1
ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr7_+_97361388 7.36 ENST00000350485.4
ENST00000346867.4
TAC1
tachykinin, precursor 1
chr16_+_66914264 7.27 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr22_-_21213029 7.25 ENST00000572273.1
ENST00000255882.6
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr8_-_82395461 7.25 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chr5_-_176057365 7.24 ENST00000310112.3
SNCB
synuclein, beta
chr15_-_77197620 7.16 ENST00000565970.1
ENST00000563290.1
ENST00000565372.1
ENST00000564177.1
ENST00000568382.1
ENST00000563919.1
SCAPER
S-phase cyclin A-associated protein in the ER
chr9_-_90589586 7.13 ENST00000325303.8
ENST00000375883.3
CDK20
cyclin-dependent kinase 20
chr6_-_84419101 7.04 ENST00000520302.1
ENST00000520213.1
ENST00000439399.2
ENST00000428679.2
ENST00000437520.1
SNAP91
synaptosomal-associated protein, 91kDa
chr8_+_21915368 7.02 ENST00000265800.5
ENST00000517418.1
DMTN
dematin actin binding protein
chr1_+_3816936 7.01 ENST00000413332.1
ENST00000442673.1
ENST00000439488.1
RP13-15E13.1
long intergenic non-protein coding RNA 1134
chr2_-_89399845 6.92 ENST00000479981.1
IGKV1-16
immunoglobulin kappa variable 1-16
chr19_-_12833361 6.92 ENST00000592287.1
TNPO2
transportin 2
chr19_-_12886327 6.90 ENST00000397668.3
ENST00000587178.1
ENST00000264827.5
HOOK2
hook microtubule-tethering protein 2
chr19_-_49137762 6.83 ENST00000593500.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr3_-_127317047 6.82 ENST00000462228.1
ENST00000490643.1
TPRA1
transmembrane protein, adipocyte asscociated 1
chr16_+_2097970 6.81 ENST00000382538.6
ENST00000401874.2
ENST00000353929.4
TSC2
tuberous sclerosis 2
chrX_+_55744166 6.77 ENST00000374941.4
ENST00000414239.1
RRAGB
Ras-related GTP binding B
chr22_-_39637135 6.75 ENST00000440375.1
PDGFB
platelet-derived growth factor beta polypeptide
chr1_+_160085501 6.73 ENST00000361216.3
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr12_+_117176090 6.73 ENST00000257575.4
ENST00000407967.3
ENST00000392549.2
RNFT2
ring finger protein, transmembrane 2
chr9_+_6757634 6.72 ENST00000543771.1
ENST00000401787.3
ENST00000381306.3
ENST00000381309.3
KDM4C
lysine (K)-specific demethylase 4C
chr3_+_112280857 6.72 ENST00000492406.1
ENST00000468642.1
SLC35A5
solute carrier family 35, member A5
chr12_-_123849374 6.65 ENST00000602398.1
ENST00000602750.1
SBNO1
strawberry notch homolog 1 (Drosophila)
chr11_-_18343669 6.47 ENST00000396253.3
ENST00000349215.3
ENST00000438420.2
HPS5
Hermansky-Pudlak syndrome 5
chr2_-_183903133 6.45 ENST00000361354.4
NCKAP1
NCK-associated protein 1
chr7_+_116593568 6.44 ENST00000446490.1
ST7
suppression of tumorigenicity 7
chr3_-_122512619 6.39 ENST00000383659.1
ENST00000306103.2
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr4_-_100242549 6.36 ENST00000305046.8
ENST00000394887.3
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
chr10_-_50970382 6.36 ENST00000419399.1
ENST00000432695.1
OGDHL
oxoglutarate dehydrogenase-like
chrX_+_153656978 6.33 ENST00000369762.2
ENST00000422890.1
ATP6AP1
ATPase, H+ transporting, lysosomal accessory protein 1
chr14_+_45431379 6.33 ENST00000361577.3
ENST00000361462.2
ENST00000382233.2
FAM179B
family with sequence similarity 179, member B
chr16_+_87425381 6.28 ENST00000268607.5
MAP1LC3B
microtubule-associated protein 1 light chain 3 beta
chr5_-_132299313 6.19 ENST00000265343.5
AFF4
AF4/FMR2 family, member 4
chrX_-_9734004 6.18 ENST00000467482.1
ENST00000380929.2
GPR143
G protein-coupled receptor 143
chrX_+_55744228 6.14 ENST00000262850.7
RRAGB
Ras-related GTP binding B

Network of associatons between targets according to the STRING database.

First level regulatory network of SREBF1_TFE3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
20.3 81.2 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
15.2 60.9 GO:0002086 maltose metabolic process(GO:0000023) diaphragm contraction(GO:0002086)
12.3 61.3 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
6.9 41.5 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
6.7 20.2 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
6.3 18.9 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
5.5 49.4 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
5.3 58.8 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
5.1 20.6 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
4.8 14.4 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
4.6 13.7 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
4.4 17.5 GO:1900241 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
4.3 13.0 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
4.3 21.4 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
4.1 24.4 GO:0015811 L-cystine transport(GO:0015811)
4.0 20.1 GO:0009608 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
3.9 27.5 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
3.9 31.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
3.6 10.9 GO:0071557 histone H3-K27 demethylation(GO:0071557)
3.6 18.1 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
3.6 10.7 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
3.5 74.4 GO:0007035 vacuolar acidification(GO:0007035)
3.4 34.3 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
3.4 16.9 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
3.3 9.9 GO:0006982 response to lipid hydroperoxide(GO:0006982)
3.2 16.1 GO:0000189 MAPK import into nucleus(GO:0000189)
3.0 9.1 GO:0051039 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
3.0 9.0 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
2.8 53.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
2.8 5.6 GO:0048286 lung alveolus development(GO:0048286)
2.7 2.7 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
2.7 10.7 GO:0061528 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
2.6 12.9 GO:0036369 transcription factor catabolic process(GO:0036369)
2.6 10.2 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
2.4 21.9 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
2.3 7.0 GO:1900063 regulation of peroxisome organization(GO:1900063)
2.3 9.0 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
2.2 8.9 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
2.2 4.4 GO:0000101 sulfur amino acid transport(GO:0000101)
2.2 17.4 GO:0070459 prolactin secretion(GO:0070459)
2.1 10.6 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
2.0 6.1 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
2.0 56.6 GO:0006884 cell volume homeostasis(GO:0006884)
2.0 6.0 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
2.0 11.8 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
2.0 11.8 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
2.0 33.2 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
1.9 7.8 GO:0042360 vitamin E metabolic process(GO:0042360)
1.9 5.8 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
1.9 19.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
1.9 15.4 GO:1901525 negative regulation of macromitophagy(GO:1901525)
1.8 12.9 GO:1990253 cellular response to leucine starvation(GO:1990253)
1.8 5.5 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
1.8 5.5 GO:0002904 B cell negative selection(GO:0002352) positive regulation of B cell apoptotic process(GO:0002904) post-embryonic camera-type eye morphogenesis(GO:0048597) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) apoptotic process involved in embryonic digit morphogenesis(GO:1902263) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) positive regulation of apoptotic DNA fragmentation(GO:1902512) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
1.8 5.4 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
1.8 5.4 GO:0006788 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806)
1.8 3.6 GO:1904978 regulation of endosome organization(GO:1904978)
1.8 5.3 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
1.7 5.2 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
1.7 12.0 GO:0046465 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
1.7 5.0 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
1.7 5.0 GO:0002276 basophil activation involved in immune response(GO:0002276)
1.7 16.8 GO:0034058 endosomal vesicle fusion(GO:0034058)
1.6 1.6 GO:1903487 regulation of lactation(GO:1903487)
1.6 9.4 GO:0006824 cobalt ion transport(GO:0006824)
1.6 6.2 GO:0023021 glucosylceramide catabolic process(GO:0006680) termination of signal transduction(GO:0023021) beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
1.6 7.8 GO:1904579 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) response to hypobaric hypoxia(GO:1990910)
1.5 4.5 GO:0015670 carbon dioxide transport(GO:0015670)
1.5 15.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
1.5 8.9 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
1.5 5.9 GO:0006542 glutamine biosynthetic process(GO:0006542)
1.5 5.9 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
1.5 4.4 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
1.4 5.7 GO:2001206 positive regulation of osteoclast development(GO:2001206)
1.4 24.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
1.4 12.7 GO:0016191 synaptic vesicle uncoating(GO:0016191)
1.4 8.5 GO:0098535 de novo centriole assembly(GO:0098535)
1.4 16.7 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
1.3 6.7 GO:1900920 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
1.3 7.7 GO:0071105 response to interleukin-11(GO:0071105)
1.3 20.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
1.3 2.5 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
1.2 9.9 GO:0006526 arginine biosynthetic process(GO:0006526)
1.2 3.7 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
1.2 4.8 GO:0009386 translational attenuation(GO:0009386)
1.2 6.0 GO:0046203 spermidine catabolic process(GO:0046203)
1.2 1.2 GO:0048754 branching morphogenesis of an epithelial tube(GO:0048754) morphogenesis of a branching epithelium(GO:0061138)
1.2 3.5 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
1.2 7.0 GO:0070560 protein secretion by platelet(GO:0070560)
1.2 2.3 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
1.2 5.8 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
1.1 3.4 GO:0003285 septum secundum development(GO:0003285)
1.1 24.7 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
1.1 4.5 GO:0006498 N-terminal protein lipidation(GO:0006498)
1.1 5.6 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
1.1 13.4 GO:0042118 endothelial cell activation(GO:0042118)
1.1 19.0 GO:0006265 DNA topological change(GO:0006265)
1.1 4.5 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
1.1 11.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
1.1 3.2 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144) circadian temperature homeostasis(GO:0060086)
1.1 6.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
1.1 3.2 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
1.0 1.0 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
1.0 3.1 GO:0036090 cleavage furrow ingression(GO:0036090)
1.0 11.5 GO:0042908 xenobiotic transport(GO:0042908)
1.0 4.2 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
1.0 3.1 GO:0071359 cellular response to dsRNA(GO:0071359)
1.0 3.1 GO:0061055 myotome development(GO:0061055)
1.0 5.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
1.0 23.3 GO:0006895 Golgi to endosome transport(GO:0006895)
1.0 12.1 GO:0030321 transepithelial chloride transport(GO:0030321)
1.0 10.0 GO:0016081 synaptic vesicle docking(GO:0016081)
1.0 5.0 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
1.0 8.0 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
1.0 5.0 GO:0097338 response to clozapine(GO:0097338)
1.0 29.0 GO:0097352 autophagosome maturation(GO:0097352)
1.0 6.7 GO:0070544 histone H3-K36 demethylation(GO:0070544)
1.0 7.7 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
1.0 1.9 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.9 5.6 GO:0043129 surfactant homeostasis(GO:0043129)
0.9 2.7 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.9 22.5 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.9 3.6 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.9 1.7 GO:0097327 response to antineoplastic agent(GO:0097327)
0.8 10.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.8 5.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.8 2.5 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.8 1.6 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.8 18.0 GO:0007567 parturition(GO:0007567)
0.8 7.4 GO:0006069 ethanol oxidation(GO:0006069)
0.8 12.2 GO:0000338 protein deneddylation(GO:0000338)
0.8 3.2 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.8 2.4 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.8 4.7 GO:0060592 mammary gland formation(GO:0060592)
0.8 9.4 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.8 2.3 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
0.8 3.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.8 5.4 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.8 3.0 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.8 25.1 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.8 2.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.8 3.8 GO:1990034 calcium ion export from cell(GO:1990034)
0.8 10.5 GO:0035878 nail development(GO:0035878)
0.7 2.2 GO:0010040 response to iron(II) ion(GO:0010040)
0.7 2.2 GO:1903012 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) positive regulation of bone development(GO:1903012) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.7 6.4 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.7 6.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.7 3.5 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.7 12.0 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.7 4.9 GO:1903232 melanosome assembly(GO:1903232)
0.7 3.5 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.7 5.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.7 5.5 GO:0015886 heme transport(GO:0015886)
0.7 8.2 GO:0006089 lactate metabolic process(GO:0006089)
0.7 2.0 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.7 2.7 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.7 2.0 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.7 0.7 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.6 3.2 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.6 7.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.6 1.9 GO:0070295 renal water absorption(GO:0070295)
0.6 14.1 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.6 7.0 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.6 1.9 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.6 12.7 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.6 7.0 GO:0009414 response to water deprivation(GO:0009414)
0.6 20.2 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.6 11.8 GO:0050872 white fat cell differentiation(GO:0050872)
0.6 3.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.6 6.7 GO:1902224 ketone body metabolic process(GO:1902224)
0.6 3.1 GO:0070633 transepithelial transport(GO:0070633)
0.6 1.8 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.6 4.8 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.6 15.4 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.6 1.8 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.6 1.7 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.6 1.7 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.6 1.7 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.6 2.8 GO:0046618 drug export(GO:0046618)
0.6 14.0 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.6 2.2 GO:0005985 sucrose metabolic process(GO:0005985)
0.5 1.6 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
0.5 15.7 GO:0010669 epithelial structure maintenance(GO:0010669)
0.5 4.3 GO:0040016 embryonic cleavage(GO:0040016)
0.5 2.7 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.5 3.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.5 2.7 GO:0032898 nerve growth factor processing(GO:0032455) neurotrophin production(GO:0032898)
0.5 2.1 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.5 7.3 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.5 2.5 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.5 2.5 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.5 6.5 GO:0019374 galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374)
0.5 1.5 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.5 1.0 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.5 1.5 GO:0097359 UDP-glucosylation(GO:0097359)
0.5 2.0 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.5 5.9 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.5 11.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.5 5.4 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.5 3.8 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.5 3.3 GO:0046485 ether lipid metabolic process(GO:0046485) regulation of adipose tissue development(GO:1904177)
0.5 5.2 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.5 2.8 GO:0006689 ganglioside catabolic process(GO:0006689)
0.5 12.4 GO:0006491 N-glycan processing(GO:0006491)
0.5 3.2 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.5 1.4 GO:0019086 late viral transcription(GO:0019086)
0.4 4.4 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.4 1.7 GO:1903564 regulation of protein localization to cilium(GO:1903564)
0.4 1.3 GO:0010887 detection of endogenous stimulus(GO:0009726) negative regulation of cholesterol storage(GO:0010887) response to high density lipoprotein particle(GO:0055099)
0.4 17.6 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.4 4.7 GO:0030043 actin filament fragmentation(GO:0030043)
0.4 57.8 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.4 21.2 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.4 4.6 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.4 6.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.4 0.8 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.4 3.3 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.4 3.7 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.4 13.9 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.4 1.6 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.4 4.4 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.4 14.3 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.4 1.6 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.4 5.8 GO:0014029 neural crest formation(GO:0014029)
0.4 1.2 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.4 2.7 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.4 1.1 GO:1900075 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.4 3.0 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.4 8.2 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.4 1.8 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.4 1.1 GO:1903401 L-lysine transmembrane transport(GO:1903401)
0.4 5.8 GO:0002021 response to dietary excess(GO:0002021)
0.4 24.9 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.4 4.6 GO:0016264 gap junction assembly(GO:0016264)
0.4 1.8 GO:0072021 ascending thin limb development(GO:0072021) thick ascending limb development(GO:0072023) metanephric ascending thin limb development(GO:0072218) metanephric thick ascending limb development(GO:0072233)
0.4 2.8 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.4 1.1 GO:0001928 regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
0.4 9.1 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.3 0.3 GO:0043317 regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318)
0.3 2.1 GO:0051012 microtubule sliding(GO:0051012)
0.3 19.5 GO:0051865 protein autoubiquitination(GO:0051865)
0.3 1.0 GO:0006566 threonine metabolic process(GO:0006566)
0.3 2.4 GO:0090647 modulation of age-related behavioral decline(GO:0090647)
0.3 1.7 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.3 1.0 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.3 4.7 GO:0090382 phagosome maturation(GO:0090382)
0.3 1.3 GO:0007288 sperm axoneme assembly(GO:0007288)
0.3 1.0 GO:0046710 GDP metabolic process(GO:0046710)
0.3 11.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.3 12.7 GO:0097484 dendrite extension(GO:0097484)
0.3 4.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.3 1.6 GO:1903525 regulation of membrane tubulation(GO:1903525) positive regulation of membrane tubulation(GO:1903527)
0.3 4.5 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.3 3.5 GO:0048484 enteric nervous system development(GO:0048484)
0.3 9.5 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.3 5.3 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.3 3.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.3 1.6 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.3 8.4 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.3 25.8 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.3 3.1 GO:0019695 choline metabolic process(GO:0019695)
0.3 0.6 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.3 6.0 GO:0071420 cellular response to histamine(GO:0071420)
0.3 8.4 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.3 1.4 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.3 1.1 GO:0030879 mammary gland development(GO:0030879)
0.3 2.0 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.3 7.8 GO:0008045 motor neuron axon guidance(GO:0008045)
0.3 4.2 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.3 1.1 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.3 5.7 GO:0042438 melanin biosynthetic process(GO:0042438)
0.3 1.9 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.3 2.2 GO:0032106 positive regulation of macroautophagy(GO:0016239) positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.3 0.8 GO:0042823 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.3 1.1 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.3 3.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.3 1.0 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.3 1.0 GO:0032782 bile acid secretion(GO:0032782)
0.2 2.0 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.2 2.5 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.2 1.0 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.2 8.9 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.2 3.3 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.2 0.7 GO:0002384 hepatic immune response(GO:0002384)
0.2 2.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.2 0.7 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.2 1.6 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.2 1.4 GO:0061525 hindgut morphogenesis(GO:0007442) embryonic hindgut morphogenesis(GO:0048619) hindgut development(GO:0061525)
0.2 3.6 GO:0019941 modification-dependent protein catabolic process(GO:0019941) modification-dependent macromolecule catabolic process(GO:0043632)
0.2 12.5 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.2 2.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.2 7.1 GO:0097178 ruffle assembly(GO:0097178)
0.2 6.0 GO:0033344 cholesterol efflux(GO:0033344)
0.2 0.6 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.2 1.9 GO:0042423 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.2 6.1 GO:0006839 mitochondrial transport(GO:0006839)
0.2 1.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 1.8 GO:0001887 selenium compound metabolic process(GO:0001887)
0.2 2.0 GO:0045329 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.2 1.0 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.2 2.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.2 2.4 GO:0030048 actin filament-based movement(GO:0030048)
0.2 3.0 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.2 3.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.2 1.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2 1.6 GO:0021527 ventral spinal cord interneuron differentiation(GO:0021514) spinal cord association neuron differentiation(GO:0021527)
0.2 0.8 GO:0043335 protein unfolding(GO:0043335)
0.2 4.1 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.2 1.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 0.4 GO:1903726 negative regulation of phospholipid metabolic process(GO:1903726)
0.2 3.8 GO:0015695 organic cation transport(GO:0015695)
0.2 3.0 GO:0097503 sialylation(GO:0097503)
0.2 3.2 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.2 0.9 GO:0044351 macropinocytosis(GO:0044351)
0.2 1.3 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.2 25.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 0.5 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.2 8.3 GO:0042417 dopamine metabolic process(GO:0042417)
0.2 1.2 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2 2.5 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.2 12.8 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.2 1.6 GO:0035376 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.2 3.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 0.7 GO:0009804 coumarin metabolic process(GO:0009804)
0.2 0.7 GO:0071205 protein localization to paranode region of axon(GO:0002175) protein localization to juxtaparanode region of axon(GO:0071205)
0.2 2.5 GO:0021895 cerebral cortex neuron differentiation(GO:0021895)
0.2 4.0 GO:0007530 sex determination(GO:0007530)
0.2 1.2 GO:0051603 proteolysis involved in cellular protein catabolic process(GO:0051603)
0.2 1.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 0.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2 0.5 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.2 1.3 GO:0007270 neuron-neuron synaptic transmission(GO:0007270)
0.2 2.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 1.7 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.2 0.6 GO:0043589 skin morphogenesis(GO:0043589)
0.2 5.1 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.2 4.9 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.2 4.9 GO:0045776 negative regulation of blood pressure(GO:0045776)
0.2 0.8 GO:0038161 prolactin signaling pathway(GO:0038161)
0.2 1.5 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.2 8.9 GO:0006953 acute-phase response(GO:0006953)
0.1 0.6 GO:0070384 Harderian gland development(GO:0070384)
0.1 0.7 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 5.3 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.1 1.0 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 1.6 GO:0060539 diaphragm development(GO:0060539)
0.1 2.4 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.1 1.2 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.5 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 1.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 3.5 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 0.6 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.1 1.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 3.5 GO:0048813 dendrite morphogenesis(GO:0048813)
0.1 6.0 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 5.8 GO:0006513 protein monoubiquitination(GO:0006513)
0.1 2.1 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 0.6 GO:0032006 regulation of TOR signaling(GO:0032006)
0.1 1.4 GO:0036508 protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) endoplasmic reticulum mannose trimming(GO:1904380)
0.1 0.4 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 1.9 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 0.8 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.1 0.4 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.1 1.1 GO:0006600 creatine metabolic process(GO:0006600)
0.1 2.4 GO:0005980 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 1.4 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.7 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.1 0.5 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 0.3 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.4 GO:0048701 embryonic cranial skeleton morphogenesis(GO:0048701)
0.1 0.3 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.1 1.5 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.1 5.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 0.4 GO:0044241 lipid digestion(GO:0044241)
0.1 4.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.7 GO:0006768 biotin metabolic process(GO:0006768)
0.1 6.1 GO:0006023 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.1 0.3 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.1 1.3 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.1 2.6 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.1 0.5 GO:0021794 thalamus development(GO:0021794)
0.1 1.1 GO:0030220 platelet formation(GO:0030220)
0.1 0.7 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 15.3 GO:0006457 protein folding(GO:0006457)
0.1 2.0 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 1.7 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.1 1.4 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.1 0.4 GO:0045359 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1 0.5 GO:0097104 postsynaptic membrane assembly(GO:0097104)
0.1 5.8 GO:0030282 bone mineralization(GO:0030282)
0.1 0.4 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 3.0 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 0.1 GO:1902954 early endosome to recycling endosome transport(GO:0061502) regulation of early endosome to recycling endosome transport(GO:1902954)
0.1 0.9 GO:0072348 sulfur compound transport(GO:0072348)
0.1 8.0 GO:0002576 platelet degranulation(GO:0002576)
0.1 0.9 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.1 2.2 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.1 0.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 1.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.2 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.1 1.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 2.9 GO:0030593 neutrophil chemotaxis(GO:0030593)
0.1 2.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 6.5 GO:0070268 cornification(GO:0070268)
0.1 2.0 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.1 1.8 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 0.6 GO:1903432 regulation of TORC1 signaling(GO:1903432)
0.1 0.2 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1 0.5 GO:0001696 gastric acid secretion(GO:0001696)
0.1 0.8 GO:0046320 regulation of fatty acid oxidation(GO:0046320)
0.1 1.8 GO:1903146 regulation of mitophagy(GO:1903146)
0.1 4.2 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 0.3 GO:0070875 positive regulation of glycogen biosynthetic process(GO:0045725) positive regulation of glycogen metabolic process(GO:0070875)
0.0 0.5 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 0.7 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 2.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.4 GO:1901032 negative regulation of response to reactive oxygen species(GO:1901032) negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.0 0.4 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.5 GO:1900116 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 1.7 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 1.5 GO:0014047 glutamate secretion(GO:0014047)
0.0 1.6 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 1.0 GO:0016311 dephosphorylation(GO:0016311)
0.0 1.0 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.0 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.2 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 1.3 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 1.1 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 2.2 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.5 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.5 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.5 GO:0016246 RNA interference(GO:0016246)
0.0 3.1 GO:0015992 proton transport(GO:0015992)
0.0 1.3 GO:0019233 sensory perception of pain(GO:0019233)
0.0 1.1 GO:0032945 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672) negative regulation of leukocyte proliferation(GO:0070664)
0.0 0.6 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.0 0.7 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.5 GO:0007416 synapse assembly(GO:0007416)
0.0 0.1 GO:0002467 germinal center formation(GO:0002467)
0.0 0.3 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.3 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.3 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.1 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.5 GO:0071277 cellular response to calcium ion(GO:0071277)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
12.1 96.5 GO:0097208 alveolar lamellar body(GO:0097208)
10.4 41.5 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
7.7 53.6 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
6.4 32.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
6.3 50.4 GO:0005672 transcription factor TFIIA complex(GO:0005672)
4.3 17.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
4.2 58.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
3.9 15.8 GO:0033596 TSC1-TSC2 complex(GO:0033596)
3.4 10.1 GO:0019034 viral replication complex(GO:0019034)
2.7 37.6 GO:0030897 HOPS complex(GO:0030897)
2.7 10.7 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
2.5 25.4 GO:0097413 Lewy body(GO:0097413)
2.5 14.7 GO:0000138 Golgi trans cisterna(GO:0000138)
2.3 13.5 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
2.2 8.8 GO:0033263 CORVET complex(GO:0033263)
2.1 15.0 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
1.8 21.4 GO:0060077 inhibitory synapse(GO:0060077)
1.7 245.7 GO:0043202 lysosomal lumen(GO:0043202)
1.6 6.4 GO:1990246 uniplex complex(GO:1990246)
1.5 10.8 GO:1990812 growth cone filopodium(GO:1990812)
1.5 6.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
1.5 11.9 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
1.4 9.8 GO:0097452 GAIT complex(GO:0097452)
1.2 6.0 GO:0089701 U2AF(GO:0089701)
1.1 5.6 GO:0071546 perinucleolar chromocenter(GO:0010370) pi-body(GO:0071546)
1.1 18.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
1.1 7.7 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
1.1 16.9 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
1.0 23.2 GO:0031082 BLOC complex(GO:0031082)
0.9 50.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.9 6.4 GO:0035371 microtubule plus-end(GO:0035371)
0.9 14.2 GO:0097418 neurofibrillary tangle(GO:0097418)
0.8 2.5 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.8 6.4 GO:0036157 outer dynein arm(GO:0036157)
0.7 5.9 GO:0097386 glial cell projection(GO:0097386)
0.7 3.3 GO:0000801 central element(GO:0000801)
0.7 4.0 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.6 15.5 GO:0031143 pseudopodium(GO:0031143)
0.6 16.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.6 13.5 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.6 8.8 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.5 43.9 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.5 1.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.5 1.0 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.5 4.6 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.5 3.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.5 5.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.5 5.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.5 4.3 GO:0005827 polar microtubule(GO:0005827)
0.5 3.7 GO:0030914 STAGA complex(GO:0030914)
0.5 6.4 GO:0031209 SCAR complex(GO:0031209)
0.4 7.6 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.4 3.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.4 4.7 GO:0097470 ribbon synapse(GO:0097470)
0.4 1.7 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.4 3.8 GO:0042788 polysomal ribosome(GO:0042788)
0.4 19.7 GO:0035577 azurophil granule membrane(GO:0035577)
0.4 38.8 GO:0005776 autophagosome(GO:0005776)
0.4 18.9 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.4 5.8 GO:0005869 dynactin complex(GO:0005869)
0.4 50.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.4 6.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.4 33.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.4 8.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.4 2.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.3 1.7 GO:0033503 HULC complex(GO:0033503)
0.3 4.6 GO:0035102 PRC1 complex(GO:0035102)
0.3 1.3 GO:0002177 manchette(GO:0002177)
0.3 8.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.3 9.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.3 3.1 GO:0070938 contractile ring(GO:0070938)
0.3 20.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.3 23.4 GO:0005796 Golgi lumen(GO:0005796)
0.3 1.9 GO:1990769 proximal neuron projection(GO:1990769)
0.3 2.2 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.3 12.3 GO:0009925 basal plasma membrane(GO:0009925)
0.3 12.3 GO:0008180 COP9 signalosome(GO:0008180)
0.3 3.6 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.3 2.0 GO:0032059 bleb(GO:0032059)
0.3 1.7 GO:0032444 activin responsive factor complex(GO:0032444)
0.3 4.3 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.3 3.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.3 6.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.3 2.5 GO:0042587 glycogen granule(GO:0042587)
0.3 1.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.3 4.6 GO:0005922 connexon complex(GO:0005922)
0.3 8.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.3 82.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.3 3.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.3 44.9 GO:0005770 late endosome(GO:0005770)
0.3 6.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.3 6.7 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.3 39.6 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.3 3.3 GO:0031904 endosome lumen(GO:0031904)
0.2 5.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 17.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.2 11.1 GO:0005801 cis-Golgi network(GO:0005801)
0.2 16.9 GO:0034707 chloride channel complex(GO:0034707)
0.2 0.7 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 2.1 GO:0097427 microtubule bundle(GO:0097427)
0.2 3.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.2 16.6 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 5.4 GO:0001533 cornified envelope(GO:0001533)
0.2 16.5 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.2 2.0 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.2 4.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 1.7 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.2 0.6 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.2 12.4 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.2 20.6 GO:0032587 ruffle membrane(GO:0032587)
0.2 1.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.2 9.8 GO:0005604 basement membrane(GO:0005604)
0.2 3.7 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.2 1.1 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.2 1.9 GO:0042611 MHC protein complex(GO:0042611) MHC class I protein complex(GO:0042612)
0.2 9.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 10.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 8.2 GO:0043198 dendritic shaft(GO:0043198)
0.2 18.2 GO:0030175 filopodium(GO:0030175)
0.2 4.0 GO:0030057 desmosome(GO:0030057)
0.2 8.0 GO:0005844 polysome(GO:0005844)
0.2 2.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 16.7 GO:0005802 trans-Golgi network(GO:0005802)
0.2 21.0 GO:0043209 myelin sheath(GO:0043209)
0.1 7.5 GO:0001726 ruffle(GO:0001726)
0.1 2.0 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 1.9 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 13.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 1.9 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 3.6 GO:0002102 podosome(GO:0002102)
0.1 26.6 GO:0030424 axon(GO:0030424)
0.1 3.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 1.4 GO:0005883 neurofilament(GO:0005883)
0.1 4.9 GO:0000139 Golgi membrane(GO:0000139)
0.1 95.4 GO:0045202 synapse(GO:0045202)
0.1 10.2 GO:0005814 centriole(GO:0005814)
0.1 3.0 GO:0005682 U5 snRNP(GO:0005682)
0.1 1.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 11.4 GO:0030133 transport vesicle(GO:0030133)
0.1 1.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.3 GO:0034451 centriolar satellite(GO:0034451)
0.1 27.4 GO:0005929 cilium(GO:0005929)
0.1 0.8 GO:0005579 membrane attack complex(GO:0005579)
0.1 2.7 GO:0001772 immunological synapse(GO:0001772)
0.1 0.6 GO:0031931 TORC1 complex(GO:0031931)
0.1 4.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 103.6 GO:0005615 extracellular space(GO:0005615)
0.1 0.5 GO:0000800 lateral element(GO:0000800)
0.1 1.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 1.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 2.4 GO:0005811 lipid particle(GO:0005811)
0.1 2.1 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.2 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.1 1.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 1.6 GO:0043235 receptor complex(GO:0043235)
0.0 1.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 1.1 GO:0005871 kinesin complex(GO:0005871)
0.0 4.8 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.3 GO:0005915 zonula adherens(GO:0005915)
0.0 2.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 3.2 GO:0030018 Z disc(GO:0030018)
0.0 2.0 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 2.8 GO:0016605 PML body(GO:0016605)
0.0 70.0 GO:0016021 integral component of membrane(GO:0016021)
0.0 0.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.3 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0045277 mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
20.3 60.9 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
12.3 61.3 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
11.3 45.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
7.1 28.3 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
7.0 56.4 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
5.0 15.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
4.8 19.3 GO:0017040 ceramidase activity(GO:0017040)
4.8 14.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
4.7 18.9 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
4.4 26.6 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
4.3 12.8 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
4.1 24.4 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
4.0 23.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
3.9 31.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
3.6 10.9 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
3.6 39.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
3.5 10.4 GO:0005137 interleukin-5 receptor binding(GO:0005137)
3.5 31.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
3.3 73.0 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
3.2 12.9 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
3.2 73.8 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
3.2 41.5 GO:0015929 hexosaminidase activity(GO:0015929)
2.9 17.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
2.7 10.7 GO:0047298 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
2.7 5.4 GO:0004630 phospholipase D activity(GO:0004630)
2.6 15.9 GO:0004565 beta-galactosidase activity(GO:0004565)
2.6 7.8 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
2.4 14.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
2.3 9.0 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
2.2 8.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
2.1 8.4 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
2.1 21.0 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
2.1 4.2 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
2.0 12.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
2.0 6.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
2.0 18.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
2.0 44.5 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
2.0 6.0 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
1.9 19.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
1.9 5.6 GO:0034584 piRNA binding(GO:0034584)
1.9 1.9 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
1.9 22.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
1.8 5.5 GO:0015439 heme-transporting ATPase activity(GO:0015439)
1.7 5.2 GO:0070538 oleic acid binding(GO:0070538)
1.7 28.8 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
1.6 6.2 GO:0004348 glucosylceramidase activity(GO:0004348)
1.5 6.2 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
1.5 30.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
1.5 15.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
1.5 5.9 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
1.5 4.4 GO:0016833 oxo-acid-lyase activity(GO:0016833)
1.5 16.3 GO:0030274 LIM domain binding(GO:0030274)
1.4 11.5 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
1.4 18.5 GO:0008199 ferric iron binding(GO:0008199)
1.4 12.4 GO:0043426 MRF binding(GO:0043426)
1.4 5.4 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
1.3 3.8 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
1.2 3.7 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
1.2 7.4 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
1.2 10.9 GO:0045545 syndecan binding(GO:0045545)
1.2 29.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
1.2 6.0 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
1.1 3.4 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
1.1 24.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
1.1 8.6 GO:0034235 GPI anchor binding(GO:0034235)
1.0 10.4 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
1.0 6.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
1.0 20.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
1.0 3.1 GO:0004103 choline kinase activity(GO:0004103)
1.0 13.3 GO:1903136 cuprous ion binding(GO:1903136)
1.0 3.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
1.0 12.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
1.0 3.0 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
1.0 62.8 GO:0005507 copper ion binding(GO:0005507)
1.0 8.9 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
1.0 38.6 GO:0017025 TBP-class protein binding(GO:0017025)
1.0 7.8 GO:0019763 immunoglobulin receptor activity(GO:0019763)
1.0 9.7 GO:0051425 PTB domain binding(GO:0051425)
1.0 6.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.9 2.8 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.9 4.7 GO:0061665 SUMO ligase activity(GO:0061665)
0.9 20.5 GO:0004707 MAP kinase activity(GO:0004707)
0.9 5.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.9 5.4 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.9 91.0 GO:0001618 virus receptor activity(GO:0001618)
0.9 12.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.9 11.3 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.9 2.6 GO:1904288 BAT3 complex binding(GO:1904288)
0.9 6.0 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.9 9.4 GO:0031419 cobalamin binding(GO:0031419)
0.8 2.5 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.8 12.5 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.8 3.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.8 3.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.8 3.2 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.8 3.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.8 3.0 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.8 3.0 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.7 2.2 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.7 0.7 GO:0034618 arginine binding(GO:0034618)
0.7 3.5 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.7 4.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.7 5.5 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.7 2.0 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.7 3.3 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.6 3.1 GO:0070097 delta-catenin binding(GO:0070097)
0.6 2.4 GO:0051787 misfolded protein binding(GO:0051787)
0.6 1.8 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.6 59.1 GO:0019905 syntaxin binding(GO:0019905)
0.6 17.4 GO:0015248 sterol transporter activity(GO:0015248)
0.6 9.6 GO:0097109 neuroligin family protein binding(GO:0097109)
0.6 5.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.6 1.8 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.6 2.3 GO:0051870 methotrexate binding(GO:0051870) folic acid receptor activity(GO:0061714)
0.6 40.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.6 2.9 GO:0034046 poly(G) binding(GO:0034046)
0.6 3.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.6 2.8 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.6 6.2 GO:0035240 dopamine binding(GO:0035240)
0.6 11.8 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.6 7.7 GO:0050693 LBD domain binding(GO:0050693)
0.6 2.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.5 1.6 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.5 3.8 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.5 5.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.5 2.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.5 1.6 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.5 22.9 GO:0050699 WW domain binding(GO:0050699)
0.5 3.2 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.5 1.0 GO:0031893 vasopressin receptor binding(GO:0031893)
0.5 2.0 GO:0015057 thrombin receptor activity(GO:0015057)
0.5 2.5 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.5 1.5 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.5 5.5 GO:0051434 BH3 domain binding(GO:0051434)
0.5 3.4 GO:0051525 NFAT protein binding(GO:0051525)
0.5 19.9 GO:0030276 clathrin binding(GO:0030276)
0.5 1.9 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.5 6.7 GO:1990239 steroid hormone binding(GO:1990239)
0.5 1.4 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.5 1.9 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.5 6.2 GO:0031005 filamin binding(GO:0031005)
0.5 2.4 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.5 2.7 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.4 13.0 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.4 19.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.4 1.7 GO:0047708 biotinidase activity(GO:0047708)
0.4 23.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.4 1.3 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.4 6.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.4 6.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.4 39.5 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.4 4.6 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.4 2.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.4 1.6 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.4 4.9 GO:0043522 leucine zipper domain binding(GO:0043522)
0.4 3.0 GO:0004111 creatine kinase activity(GO:0004111)
0.4 1.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.4 8.9 GO:0004383 guanylate cyclase activity(GO:0004383)
0.3 10.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.3 1.4 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.3 4.1 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.3 22.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.3 1.0 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.3 3.3 GO:0015250 water channel activity(GO:0015250)
0.3 6.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.3 5.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.3 0.9 GO:0051185 coenzyme transporter activity(GO:0051185)
0.3 3.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.3 4.6 GO:0005243 gap junction channel activity(GO:0005243)
0.3 1.2 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.3 7.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.3 0.8 GO:0033149 FFAT motif binding(GO:0033149)
0.3 1.1 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.3 3.8 GO:0008097 5S rRNA binding(GO:0008097)
0.3 0.8 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.3 6.9 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.3 7.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.3 0.8 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057)
0.3 10.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 0.5 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.2 3.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 8.9 GO:1901476 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.2 1.7 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 3.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 3.6 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.2 0.7 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.2 2.0 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 2.7 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.2 9.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 0.9 GO:0016160 amylase activity(GO:0016160)
0.2 1.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.2 6.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 3.5 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.2 1.9 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.2 2.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 1.9 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.2 15.2 GO:0019003 GDP binding(GO:0019003)
0.2 0.8 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.2 11.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 3.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 1.7 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.2 5.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.7 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.2 1.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 2.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 3.3 GO:0019902 phosphatase binding(GO:0019902)
0.2 2.0 GO:0008301 DNA binding, bending(GO:0008301)
0.2 1.4 GO:0039706 co-receptor binding(GO:0039706)
0.2 7.0 GO:0030507 spectrin binding(GO:0030507)
0.2 0.9 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 3.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2 2.9 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 5.1 GO:0050681 androgen receptor binding(GO:0050681)
0.2 17.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 2.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 2.1 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.2 2.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 4.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 1.8 GO:0019864 IgG binding(GO:0019864)
0.2 2.4 GO:0005522 profilin binding(GO:0005522)
0.2 5.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 33.4 GO:0003823 antigen binding(GO:0003823)
0.2 13.5 GO:0051219 phosphoprotein binding(GO:0051219)
0.2 2.3 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.2 4.1 GO:0042162 telomeric DNA binding(GO:0042162)
0.2 0.8 GO:0004925 prolactin receptor activity(GO:0004925)
0.2 6.0 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.2 3.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 4.1 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 4.3 GO:0051020 GTPase binding(GO:0051020)
0.1 0.7 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.1 0.9 GO:0050543 icosatetraenoic acid binding(GO:0050543)
0.1 2.4 GO:0016502 G-protein coupled nucleotide receptor activity(GO:0001608) purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.0 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 1.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 4.1 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.1 1.0 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.5 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 3.7 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 25.9 GO:0008083 growth factor activity(GO:0008083)
0.1 3.1 GO:0032451 demethylase activity(GO:0032451)
0.1 1.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 1.4 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 4.0 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.5 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.1 7.3 GO:0017022 myosin binding(GO:0017022)
0.1 10.5 GO:0008013 beta-catenin binding(GO:0008013)
0.1 1.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 2.7 GO:0005521 lamin binding(GO:0005521)
0.1 1.4 GO:0032407 MutSalpha complex binding(GO:0032407)
0.1 2.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 3.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 1.4 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 3.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 1.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.9 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 11.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 2.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.5 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 0.5 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.1 0.5 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.6 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.9 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 1.6 GO:0070402 NADPH binding(GO:0070402)
0.1 0.7 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 1.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.2 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 1.0 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.1 0.4 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 9.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 0.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 1.4 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.5 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 18.0 GO:0031267 small GTPase binding(GO:0031267)
0.1 8.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 3.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 2.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.8 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.1 0.9 GO:0097110 scaffold protein binding(GO:0097110)
0.1 6.4 GO:0051082 unfolded protein binding(GO:0051082)
0.1 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 2.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 4.3 GO:0019903 protein phosphatase binding(GO:0019903)
0.1 18.9 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 0.5 GO:0004969 histamine receptor activity(GO:0004969)
0.1 26.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 1.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.7 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 1.3 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 1.1 GO:0001848 complement binding(GO:0001848)
0.0 0.9 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.8 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 1.5 GO:0019894 kinesin binding(GO:0019894)
0.0 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 1.6 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 3.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.4 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 4.4 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 1.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.7 GO:0016866 intramolecular transferase activity(GO:0016866)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 1.1 GO:0051087 chaperone binding(GO:0051087)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0005506 iron ion binding(GO:0005506)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 2.1 GO:0005178 integrin binding(GO:0005178)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 19.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
1.3 53.5 ST GA12 PATHWAY G alpha 12 Pathway
1.2 71.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
1.1 36.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.8 17.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.8 24.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.7 14.1 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.6 11.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.6 9.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.6 14.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.5 28.2 PID AURORA A PATHWAY Aurora A signaling
0.5 49.4 PID LKB1 PATHWAY LKB1 signaling events
0.5 8.6 PID IL5 PATHWAY IL5-mediated signaling events
0.5 50.0 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.5 25.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.4 20.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.4 2.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.4 8.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.4 1.9 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.4 93.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.3 12.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.3 5.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3 2.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.3 13.3 PID FANCONI PATHWAY Fanconi anemia pathway
0.3 8.4 PID AP1 PATHWAY AP-1 transcription factor network
0.2 7.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 2.8 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.2 4.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 1.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 11.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.2 2.0 ST GA13 PATHWAY G alpha 13 Pathway
0.2 7.1 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 8.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.2 6.0 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.2 6.1 PID RHOA PATHWAY RhoA signaling pathway
0.2 8.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.2 19.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.2 9.2 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.2 8.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 1.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.2 3.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 8.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 3.2 PID IFNG PATHWAY IFN-gamma pathway
0.1 2.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 3.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 9.1 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 1.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 0.7 ST STAT3 PATHWAY STAT3 Pathway
0.1 1.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 1.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 0.8 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 1.6 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 3.9 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.1 2.1 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 21.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 0.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 1.7 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 1.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 2.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.1 PID FOXO PATHWAY FoxO family signaling
0.0 3.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.5 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 3.2 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 107.0 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
2.9 134.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
2.5 5.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
1.8 20.0 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
1.2 23.7 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
1.2 17.3 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
1.0 23.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
1.0 71.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
1.0 15.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.9 22.5 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.9 18.6 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.9 11.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.9 7.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.8 14.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.8 3.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.8 20.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.8 9.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.8 22.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.7 100.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.7 18.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.7 12.7 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.6 12.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.6 11.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.6 50.8 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.6 29.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.6 33.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.5 20.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.5 7.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.5 11.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.4 9.0 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.4 5.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.4 10.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.4 6.6 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.4 7.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.4 2.4 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.4 3.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.4 7.2 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.4 54.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.4 9.3 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.4 13.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.4 3.3 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.4 28.5 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.4 0.7 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.3 3.4 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.3 10.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.3 7.2 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.3 5.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.3 11.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.3 1.8 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.3 4.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 1.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 3.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 0.7 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2 4.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 5.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 3.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.2 1.0 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.2 42.0 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.2 3.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 2.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 6.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 2.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.2 4.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 13.7 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.2 2.1 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.2 1.7 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.2 3.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.2 0.6 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.1 8.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.3 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 2.0 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 1.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 2.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.8 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 4.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 2.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 0.4 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.1 3.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 2.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 4.4 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 0.4 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 10.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 1.8 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 0.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.9 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 1.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.5 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 1.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 3.0 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 2.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 4.1 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 1.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 4.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.9 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 2.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 8.5 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 1.1 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.5 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions