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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for STAT1_STAT3_BCL6

Z-value: 1.67

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Transcription factors associated with STAT1_STAT3_BCL6

Gene Symbol Gene ID Gene Info
ENSG00000115415.14 signal transducer and activator of transcription 1
ENSG00000168610.10 signal transducer and activator of transcription 3
ENSG00000113916.13 BCL6 transcription repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT1hg19_v2_chr2_-_191878874_191878976-0.427.6e-11Click!
BCL6hg19_v2_chr3_-_187454281_1874543570.291.3e-05Click!
STAT3hg19_v2_chr17_-_40540377_40540481-0.143.4e-02Click!

Activity profile of STAT1_STAT3_BCL6 motif

Sorted Z-values of STAT1_STAT3_BCL6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_27620603 88.39 ENST00000418271.1
ENST00000444114.1
RP5-1172A22.1
chr8_-_27468842 49.18 ENST00000523500.1
clusterin
chr8_-_27469196 42.37 ENST00000546343.1
ENST00000560566.1
clusterin
chr1_-_230850043 41.83 ENST00000366667.4
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr1_+_233086326 41.27 ENST00000366628.5
ENST00000366627.4
nucleoside-triphosphatase, cancer-related
chr10_-_90751038 39.11 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
actin, alpha 2, smooth muscle, aorta
chr17_+_32582293 38.82 ENST00000580907.1
ENST00000225831.4
chemokine (C-C motif) ligand 2
chr8_-_27468945 37.30 ENST00000405140.3
clusterin
chr2_+_17935383 36.94 ENST00000524465.1
ENST00000381254.2
ENST00000532257.1
GEN1 Holliday junction 5' flap endonuclease
chr3_+_187871060 36.05 ENST00000448637.1
LIM domain containing preferred translocation partner in lipoma
chr12_+_53443963 35.31 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
tensin like C1 domain containing phosphatase (tensin 2)
chr12_+_53443680 33.56 ENST00000314250.6
ENST00000451358.1
tensin like C1 domain containing phosphatase (tensin 2)
chr2_+_17935119 33.33 ENST00000317402.7
GEN1 Holliday junction 5' flap endonuclease
chr12_-_91539918 33.07 ENST00000548218.1
decorin
chr7_+_134464414 28.29 ENST00000361901.2
caldesmon 1
chr1_+_6845384 25.36 ENST00000303635.7
calmodulin binding transcription activator 1
chr8_-_120651020 25.20 ENST00000522826.1
ENST00000520066.1
ENST00000259486.6
ENST00000075322.6
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr12_+_122064398 23.38 ENST00000330079.7
ORAI calcium release-activated calcium modulator 1
chr15_-_60690932 21.65 ENST00000559818.1
annexin A2
chr9_-_89562104 20.94 ENST00000298743.7
growth arrest-specific 1
chr3_-_93692781 20.11 ENST00000394236.3
protein S (alpha)
chr16_-_75498308 19.28 ENST00000569540.1
transmembrane protein 170A
chr5_-_42812143 18.21 ENST00000514985.1
selenoprotein P, plasma, 1
chr11_+_57365150 17.60 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr14_-_21270995 17.52 ENST00000555698.1
ENST00000397970.4
ENST00000340900.3
ribonuclease, RNase A family, 1 (pancreatic)
chr9_-_117880477 17.34 ENST00000534839.1
ENST00000340094.3
ENST00000535648.1
ENST00000346706.3
ENST00000345230.3
ENST00000350763.4
tenascin C
chr7_+_134464376 17.18 ENST00000454108.1
ENST00000361675.2
caldesmon 1
chrX_+_103031421 16.75 ENST00000433491.1
ENST00000418604.1
ENST00000443502.1
proteolipid protein 1
chr10_-_62493223 16.67 ENST00000373827.2
ankyrin 3, node of Ranvier (ankyrin G)
chr11_-_111782696 16.38 ENST00000227251.3
ENST00000526180.1
crystallin, alpha B
chr14_-_21270561 16.11 ENST00000412779.2
ribonuclease, RNase A family, 1 (pancreatic)
chr7_+_74508372 15.72 ENST00000356115.5
ENST00000430511.2
ENST00000312575.7
GTF2I repeat domain containing 2B
chr1_+_163039143 15.60 ENST00000531057.1
ENST00000527809.1
ENST00000367908.4
regulator of G-protein signaling 4
chrX_+_129473859 15.43 ENST00000424447.1
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr1_-_144995074 15.39 ENST00000534536.1
phosphodiesterase 4D interacting protein
chr1_+_163038565 15.30 ENST00000421743.2
regulator of G-protein signaling 4
chr7_-_74267836 14.72 ENST00000361071.5
ENST00000453619.2
ENST00000417115.2
ENST00000405086.2
GTF2I repeat domain containing 2
chr1_-_144994909 14.32 ENST00000369347.4
ENST00000369354.3
phosphodiesterase 4D interacting protein
chr19_+_55281260 14.28 ENST00000336077.6
ENST00000291633.7
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
chr19_+_10381769 14.18 ENST00000423829.2
ENST00000588645.1
intercellular adhesion molecule 1
chr12_-_133050726 14.18 ENST00000595994.1
mucin 8
chrX_-_48931648 13.99 ENST00000376386.3
ENST00000376390.4
PRA1 domain family, member 2
chr19_+_15218180 13.78 ENST00000342784.2
ENST00000597977.1
ENST00000600440.1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr22_+_33197683 13.23 ENST00000266085.6
TIMP metallopeptidase inhibitor 3
chr20_-_18774614 13.12 ENST00000412553.1
long intergenic non-protein coding RNA 652
chr14_-_30396948 12.81 ENST00000331968.5
protein kinase D1
chr17_-_42992856 12.73 ENST00000588316.1
ENST00000435360.2
ENST00000586793.1
ENST00000588735.1
ENST00000588037.1
ENST00000592320.1
ENST00000253408.5
glial fibrillary acidic protein
chr11_-_111782484 12.57 ENST00000533971.1
crystallin, alpha B
chr5_+_40909354 12.29 ENST00000313164.9
complement component 7
chr17_+_76356516 12.28 ENST00000592569.1
RP11-806H10.4
chr1_-_68299130 12.15 ENST00000370982.3
guanine nucleotide binding protein (G protein), gamma 12
chr1_-_144994840 11.43 ENST00000369351.3
ENST00000369349.3
phosphodiesterase 4D interacting protein
chr17_+_76311791 11.25 ENST00000586321.1
AC061992.2
chr11_-_102668879 11.11 ENST00000315274.6
matrix metallopeptidase 1 (interstitial collagenase)
chr2_-_37193606 10.99 ENST00000379213.2
ENST00000263918.4
striatin, calmodulin binding protein
chr4_+_41258786 10.88 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr3_-_123512688 10.81 ENST00000475616.1
myosin light chain kinase
chr2_-_86333244 10.63 ENST00000263857.6
ENST00000409681.1
polymerase (RNA) I polypeptide A, 194kDa
chr1_+_36690011 10.54 ENST00000354618.5
ENST00000469141.2
ENST00000478853.1
thyroid hormone receptor associated protein 3
chr19_+_35168567 10.50 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
zinc finger protein 302
chr3_-_149095652 10.42 ENST00000305366.3
transmembrane 4 L six family member 1
chr8_-_120685608 10.38 ENST00000427067.2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr4_-_140005341 10.19 ENST00000379549.2
ENST00000512627.1
E74-like factor 2 (ets domain transcription factor)
chr3_+_153839149 10.09 ENST00000465093.1
ENST00000465817.1
Rho guanine nucleotide exchange factor (GEF) 26
chr3_+_45067659 10.06 ENST00000296130.4
C-type lectin domain family 3, member B
chr4_+_166300084 9.94 ENST00000402744.4
carboxypeptidase E
chr17_-_76356148 9.49 ENST00000587578.1
ENST00000330871.2
suppressor of cytokine signaling 3
chr17_+_32683456 9.48 ENST00000225844.2
chemokine (C-C motif) ligand 13
chr3_+_101568349 9.41 ENST00000326151.5
ENST00000326172.5
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr2_-_190044480 9.40 ENST00000374866.3
collagen, type V, alpha 2
chr1_-_11107280 9.37 ENST00000400897.3
ENST00000400898.3
mannan-binding lectin serine peptidase 2
chr1_-_201476274 9.21 ENST00000340006.2
cysteine and glycine-rich protein 1
chr6_-_52859046 9.18 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
glutathione S-transferase alpha 4
chr6_+_151561085 9.18 ENST00000402676.2
A kinase (PRKA) anchor protein 12
chr19_+_35168633 9.06 ENST00000505365.2
zinc finger protein 302
chr16_+_72088376 9.01 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
haptoglobin
haptoglobin-related protein
chr12_+_93964746 8.78 ENST00000536696.2
suppressor of cytokine signaling 2
chrX_-_13835461 8.71 ENST00000316715.4
ENST00000356942.5
glycoprotein M6B
chr17_-_76274572 8.68 ENST00000374945.1
RP11-219G17.4
chr5_-_132112907 8.50 ENST00000458488.2
septin 8
chr5_-_132112921 8.43 ENST00000378721.4
ENST00000378701.1
septin 8
chr10_-_33625154 8.29 ENST00000265371.4
neuropilin 1
chr1_-_144995002 8.22 ENST00000369356.4
phosphodiesterase 4D interacting protein
chr7_-_108096822 8.07 ENST00000379028.3
ENST00000413765.2
ENST00000379022.4
neuronal cell adhesion molecule
chr7_-_108096765 8.05 ENST00000379024.4
ENST00000351718.4
neuronal cell adhesion molecule
chr1_-_203155868 7.95 ENST00000255409.3
chitinase 3-like 1 (cartilage glycoprotein-39)
chrX_+_102631248 7.77 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr8_+_19796381 7.76 ENST00000524029.1
ENST00000522701.1
ENST00000311322.8
lipoprotein lipase
chr17_+_77021702 7.75 ENST00000392445.2
ENST00000354124.3
C1q and tumor necrosis factor related protein 1
chr19_+_57106647 7.72 ENST00000328070.6
zinc finger protein 71
chr12_-_10151773 7.68 ENST00000298527.6
ENST00000348658.4
C-type lectin domain family 1, member B
chr22_-_50699701 7.62 ENST00000395780.1
mitogen-activated protein kinase 12
chr1_+_22979676 7.60 ENST00000432749.2
ENST00000314933.6
complement component 1, q subcomponent, B chain
chr9_+_124088860 7.54 ENST00000373806.1
gelsolin
chr12_+_58138800 7.50 ENST00000547992.1
ENST00000552816.1
ENST00000547472.1
tetraspanin 31
chr3_+_46283916 7.47 ENST00000395940.2
chemokine (C-C motif) receptor 3
chr1_+_22979474 7.35 ENST00000509305.1
complement component 1, q subcomponent, B chain
chr11_+_46740730 7.32 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
coagulation factor II (thrombin)
chr3_+_115342159 7.31 ENST00000305124.6
growth associated protein 43
chr9_-_117853297 7.30 ENST00000542877.1
ENST00000537320.1
ENST00000341037.4
tenascin C
chr10_+_95848824 7.25 ENST00000371385.3
ENST00000371375.1
phospholipase C, epsilon 1
chr10_+_72194585 7.19 ENST00000420338.2
Uncharacterized protein
chr3_+_115342349 7.11 ENST00000393780.3
growth associated protein 43
chr4_+_158141806 7.10 ENST00000393815.2
glutamate receptor, ionotropic, AMPA 2
chr12_+_7023491 7.08 ENST00000541477.1
ENST00000229277.1
enolase 2 (gamma, neuronal)
chr5_+_172483347 7.02 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
CREB3 regulatory factor
chr6_-_56707943 7.02 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
dystonin
chr5_-_134914673 7.01 ENST00000512158.1
chemokine (C-X-C motif) ligand 14
chr14_+_94577074 6.97 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
interferon, alpha-inducible protein 27
chr1_+_17906970 6.95 ENST00000375415.1
Rho guanine nucleotide exchange factor (GEF) 10-like
chr14_-_45431091 6.92 ENST00000579157.1
ENST00000396128.4
ENST00000556500.1
kelch-like family member 28
chr2_-_128399706 6.88 ENST00000426981.1
LIM and senescent cell antigen-like domains 2
chr19_+_35773242 6.82 ENST00000222304.3
hepcidin antimicrobial peptide
chr15_+_63340647 6.79 ENST00000404484.4
tropomyosin 1 (alpha)
chr3_+_62304712 6.79 ENST00000494481.1
chromosome 3 open reading frame 14
chr19_-_49339732 6.77 ENST00000599157.1
hydroxysteroid (17-beta) dehydrogenase 14
chr19_-_44809121 6.71 ENST00000591609.1
ENST00000589799.1
ENST00000291182.4
ENST00000589248.1
zinc finger protein 235
chr3_+_46283863 6.71 ENST00000545097.1
ENST00000541018.1
chemokine (C-C motif) receptor 3
chr14_+_65381079 6.67 ENST00000549115.1
ENST00000607599.1
ENST00000548752.2
ENST00000359118.2
ENST00000552002.2
ENST00000551947.1
ENST00000551093.1
ENST00000542227.1
ENST00000447296.2
ENST00000549987.1
churchill domain containing 1
farnesyltransferase, CAAX box, beta
CHURC1-FNTB readthrough
chr4_+_158141843 6.67 ENST00000509417.1
ENST00000296526.7
glutamate receptor, ionotropic, AMPA 2
chr8_+_30300119 6.60 ENST00000520191.1
RNA binding protein with multiple splicing
chr3_-_114866084 6.47 ENST00000357258.3
zinc finger and BTB domain containing 20
chr8_-_22089845 6.44 ENST00000454243.2
phytanoyl-CoA 2-hydroxylase interacting protein
chr15_+_63340734 6.42 ENST00000560959.1
tropomyosin 1 (alpha)
chr1_-_8000872 6.36 ENST00000377507.3
tumor necrosis factor receptor superfamily, member 9
chr19_-_49339915 6.26 ENST00000263278.4
hydroxysteroid (17-beta) dehydrogenase 14
chr19_+_40502938 6.25 ENST00000599504.1
ENST00000596894.1
ENST00000601138.1
ENST00000600094.1
ENST00000347077.4
zinc finger protein 546
chr6_-_36355513 6.22 ENST00000340181.4
ENST00000373737.4
ets variant 7
chr8_-_22089533 6.21 ENST00000321613.3
phytanoyl-CoA 2-hydroxylase interacting protein
chr1_+_202431859 6.16 ENST00000391959.3
ENST00000367270.4
protein phosphatase 1, regulatory subunit 12B
chr3_+_62304648 6.15 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
chromosome 3 open reading frame 14
chr17_-_26697304 6.06 ENST00000536498.1
vitronectin
chr9_+_15422702 6.02 ENST00000380821.3
ENST00000421710.1
small nuclear RNA activating complex, polypeptide 3, 50kDa
chr1_+_171810606 6.01 ENST00000358155.4
ENST00000367733.2
ENST00000355305.5
ENST00000367731.1
dynamin 3
chr2_-_175351744 6.00 ENST00000295500.4
ENST00000392552.2
ENST00000392551.2
G protein-coupled receptor 155
chr8_+_85618155 5.97 ENST00000523850.1
ENST00000521376.1
RALY RNA binding protein-like
chr7_-_38670957 5.97 ENST00000325590.5
ENST00000428293.2
amphiphysin
chr16_-_5116025 5.96 ENST00000472572.3
ENST00000315997.5
ENST00000422873.1
ENST00000350219.4
chromosome 16 open reading frame 89
chr2_-_224467093 5.94 ENST00000305409.2
secretogranin II
chrX_-_38186811 5.92 ENST00000318842.7
retinitis pigmentosa GTPase regulator
chr3_-_52864680 5.92 ENST00000406595.1
ENST00000485816.1
ENST00000434759.3
ENST00000346281.5
ENST00000266041.4
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr4_+_8594477 5.85 ENST00000315782.6
carboxypeptidase Z
chr12_+_21679220 5.82 ENST00000256969.2
chromosome 12 open reading frame 39
chr17_+_42385927 5.77 ENST00000426726.3
ENST00000590941.1
ENST00000225441.7
RUN domain containing 3A
chr19_+_55327923 5.76 ENST00000391728.4
ENST00000326542.7
ENST00000358178.4
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
chr8_+_26371763 5.75 ENST00000521913.1
dihydropyrimidinase-like 2
chr15_-_88799661 5.73 ENST00000360948.2
ENST00000357724.2
ENST00000355254.2
ENST00000317501.3
neurotrophic tyrosine kinase, receptor, type 3
chr15_+_63340775 5.71 ENST00000559281.1
ENST00000317516.7
tropomyosin 1 (alpha)
chr17_+_40912764 5.71 ENST00000589683.1
ENST00000588928.1
receptor (G protein-coupled) activity modifying protein 2
chr7_-_38671098 5.68 ENST00000356264.2
amphiphysin
chr4_-_140005443 5.67 ENST00000510408.1
ENST00000420916.2
ENST00000358635.3
E74-like factor 2 (ets domain transcription factor)
chr9_-_21335240 5.66 ENST00000537938.1
kelch-like family member 9
chr18_+_23806437 5.66 ENST00000578121.1
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr16_-_5115913 5.61 ENST00000474471.3
chromosome 16 open reading frame 89
chr1_+_162602244 5.59 ENST00000367922.3
ENST00000367921.3
discoidin domain receptor tyrosine kinase 2
chr1_-_31845914 5.48 ENST00000373713.2
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr6_-_36355486 5.46 ENST00000538992.1
ets variant 7
chr14_-_92414055 5.45 ENST00000342058.4
fibulin 5
chr4_+_86396265 5.41 ENST00000395184.1
Rho GTPase activating protein 24
chr17_-_46691990 5.41 ENST00000576562.1
homeobox B8
chr14_-_76447494 5.39 ENST00000238682.3
transforming growth factor, beta 3
chr2_+_99797542 5.37 ENST00000338148.3
ENST00000512183.2
mitochondrial ribosomal protein L30
chromosome 2 open reading frame 15
chr15_-_83378611 5.35 ENST00000542200.1
adaptor-related protein complex 3, beta 2 subunit
chr3_+_136537911 5.33 ENST00000393079.3
solute carrier family 35, member G2
chr4_+_158141899 5.31 ENST00000264426.9
ENST00000506284.1
glutamate receptor, ionotropic, AMPA 2
chr12_+_58138664 5.27 ENST00000257910.3
tetraspanin 31
chr6_-_46889694 5.16 ENST00000283296.7
ENST00000362015.4
ENST00000456426.2
G protein-coupled receptor 116
chr4_+_155484155 5.12 ENST00000509493.1
fibrinogen beta chain
chr17_-_1619491 5.02 ENST00000570416.1
ENST00000575626.1
ENST00000610106.1
ENST00000608198.1
ENST00000609442.1
ENST00000334146.3
ENST00000576489.1
ENST00000608245.1
ENST00000609398.1
ENST00000608913.1
ENST00000574016.1
ENST00000571091.1
ENST00000573127.1
ENST00000609990.1
ENST00000576749.1
MIR22 host gene (non-protein coding)
chrX_-_137793826 5.00 ENST00000315930.6
fibroblast growth factor 13
chr3_+_136537816 4.95 ENST00000446465.2
solute carrier family 35, member G2
chr8_-_18666360 4.89 ENST00000286485.8
pleckstrin and Sec7 domain containing 3
chr14_+_45431379 4.89 ENST00000361577.3
ENST00000361462.2
ENST00000382233.2
family with sequence similarity 179, member B
chr12_+_12223867 4.86 ENST00000308721.5
BCL2-like 14 (apoptosis facilitator)
chr5_+_140501581 4.84 ENST00000194152.1
protocadherin beta 4
chr2_+_173686303 4.80 ENST00000397087.3
Rap guanine nucleotide exchange factor (GEF) 4
chr1_+_155099927 4.79 ENST00000368407.3
ephrin-A1
chr3_-_194072019 4.78 ENST00000429275.1
ENST00000323830.3
carboxypeptidase N, polypeptide 2
chrX_-_38186775 4.77 ENST00000339363.3
ENST00000309513.3
ENST00000338898.3
ENST00000342811.3
ENST00000378505.2
retinitis pigmentosa GTPase regulator
chr16_+_67198683 4.77 ENST00000517685.1
ENST00000521374.1
ENST00000584272.1
heat shock transcription factor 4
chr4_-_155511887 4.76 ENST00000302053.3
ENST00000403106.3
fibrinogen alpha chain
chr19_+_37407212 4.76 ENST00000427117.1
ENST00000587130.1
ENST00000333987.7
ENST00000415168.1
ENST00000444991.1
zinc finger protein 568
chr3_-_127455200 4.72 ENST00000398101.3
monoglyceride lipase
chr16_+_48657361 4.70 ENST00000565072.1
RP11-42I10.1
chr1_+_152850787 4.68 ENST00000368765.3
sperm mitochondria-associated cysteine-rich protein
chr12_+_13197218 4.65 ENST00000197268.8
KIAA1467
chr12_-_111021110 4.64 ENST00000354300.3
PTC7 protein phosphatase homolog (S. cerevisiae)
chr12_+_70132632 4.59 ENST00000378815.6
ENST00000483530.2
ENST00000325555.9
RAB3A interacting protein
chr2_-_106013400 4.57 ENST00000409807.1
four and a half LIM domains 2
chr5_-_132113036 4.46 ENST00000378706.1
septin 8
chrX_-_10544942 4.45 ENST00000380779.1
midline 1 (Opitz/BBB syndrome)
chr3_-_148939835 4.44 ENST00000264613.6
ceruloplasmin (ferroxidase)
chr3_+_185000729 4.43 ENST00000448876.1
ENST00000446828.1
ENST00000447637.1
ENST00000424227.1
ENST00000454237.1
mitogen-activated protein kinase kinase kinase 13
chr1_+_1370903 4.43 ENST00000338660.5
ENST00000404702.3
ENST00000476993.1
ENST00000471398.1
von Willebrand factor A domain containing 1
chr19_+_42746927 4.42 ENST00000378108.1
AC006486.1
chr11_+_66025167 4.42 ENST00000394067.2
ENST00000316924.5
ENST00000421552.1
ENST00000394078.1
kinesin light chain 2
chr1_+_150488205 4.41 ENST00000416894.1
long intergenic non-protein coding RNA 568
chr6_-_150039249 4.39 ENST00000543571.1
large tumor suppressor kinase 1
chr1_+_28655505 4.39 ENST00000373842.4
ENST00000398997.2
mediator complex subunit 18
chr12_+_102271129 4.31 ENST00000258534.8
DNA-damage regulated autophagy modulator 1

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT1_STAT3_BCL6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
23.4 70.3 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
21.5 128.8 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
13.9 41.8 GO:1903410 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
12.9 38.8 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
8.2 24.6 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
6.5 39.1 GO:0090131 mesenchyme migration(GO:0090131)
4.2 16.7 GO:0072658 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
3.6 10.9 GO:0007412 axon target recognition(GO:0007412)
3.6 10.7 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
3.5 14.2 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
3.4 13.8 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
3.3 13.2 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
3.3 9.8 GO:0048691 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
3.2 6.4 GO:2001183 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
3.2 9.5 GO:0072683 T cell extravasation(GO:0072683)
3.0 9.0 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
2.8 33.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
2.7 13.7 GO:0030070 insulin processing(GO:0030070)
2.7 16.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
2.7 10.6 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
2.6 39.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
2.4 9.5 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
2.4 18.9 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
2.3 9.4 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
2.3 7.0 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
2.3 6.8 GO:1903413 cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
2.3 6.8 GO:0035603 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
2.1 23.4 GO:0002115 store-operated calcium entry(GO:0002115)
2.1 27.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
2.0 6.0 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
1.9 7.7 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
1.9 30.8 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
1.8 12.8 GO:0089700 protein kinase D signaling(GO:0089700)
1.8 5.5 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
1.7 6.8 GO:0090678 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
1.7 8.3 GO:1902336 vestibulocochlear nerve structural organization(GO:0021649) neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) positive regulation of retinal ganglion cell axon guidance(GO:1902336) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
1.7 29.8 GO:0007021 tubulin complex assembly(GO:0007021)
1.6 27.9 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
1.5 7.5 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
1.4 7.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
1.4 14.4 GO:0016198 axon choice point recognition(GO:0016198)
1.4 10.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
1.4 14.3 GO:0002765 immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
1.4 4.2 GO:0006014 D-ribose metabolic process(GO:0006014)
1.4 10.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
1.3 5.4 GO:1905071 ossification involved in bone remodeling(GO:0043932) frontal suture morphogenesis(GO:0060364) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
1.3 4.0 GO:1904425 negative regulation of GTP binding(GO:1904425)
1.3 6.3 GO:0035936 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
1.2 12.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
1.2 4.8 GO:0014028 notochord formation(GO:0014028)
1.1 3.4 GO:0071725 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
1.1 3.4 GO:1904647 response to rotenone(GO:1904647)
1.1 6.7 GO:0018343 protein farnesylation(GO:0018343)
1.1 7.8 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890) lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
1.1 3.2 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
1.0 5.0 GO:1990834 response to odorant(GO:1990834)
1.0 15.5 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
1.0 3.8 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.9 7.3 GO:0099612 protein localization to axon(GO:0099612)
0.9 4.6 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.9 2.7 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.9 12.7 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.9 1.8 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.9 4.4 GO:0001826 inner cell mass cell differentiation(GO:0001826)
0.9 8.7 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.9 13.0 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.8 2.5 GO:0038178 complement component C5a signaling pathway(GO:0038178) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.8 5.9 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.8 10.1 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.8 17.4 GO:2001046 positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.8 2.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.8 4.7 GO:0007341 penetration of zona pellucida(GO:0007341)
0.8 7.0 GO:0008090 retrograde axonal transport(GO:0008090)
0.8 3.8 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.8 12.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.8 3.8 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.8 8.3 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.7 18.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.7 5.6 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.7 4.2 GO:0001675 acrosome assembly(GO:0001675)
0.7 2.7 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.7 4.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.7 6.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.7 2.7 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.7 2.7 GO:0007538 primary sex determination(GO:0007538)
0.7 1.3 GO:2000570 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.7 4.0 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.7 5.9 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.7 3.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.6 6.5 GO:0003360 brainstem development(GO:0003360)
0.6 7.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.6 5.7 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.6 5.7 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.6 0.6 GO:0070666 mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.6 38.4 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.6 24.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.6 3.5 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.6 4.1 GO:0035799 ureter maturation(GO:0035799)
0.6 1.1 GO:0046533 negative regulation of photoreceptor cell differentiation(GO:0046533)
0.6 1.7 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.6 3.9 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.5 16.3 GO:0015813 L-glutamate transport(GO:0015813)
0.5 10.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.5 2.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.5 8.8 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.5 3.6 GO:0008218 bioluminescence(GO:0008218)
0.5 6.6 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.5 2.5 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.5 3.5 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.5 1.9 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.5 1.9 GO:2000317 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.5 1.9 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.5 2.9 GO:0031642 negative regulation of myelination(GO:0031642)
0.5 7.6 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.5 1.9 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.5 8.9 GO:0048266 behavioral response to pain(GO:0048266)
0.5 2.8 GO:0009624 response to nematode(GO:0009624)
0.5 5.1 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.5 4.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.5 2.3 GO:0046968 peptide antigen transport(GO:0046968)
0.4 2.2 GO:0006041 glucosamine metabolic process(GO:0006041) glucose 1-phosphate metabolic process(GO:0019255)
0.4 6.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.4 1.2 GO:0032242 positive regulation of necrotic cell death(GO:0010940) regulation of nucleoside transport(GO:0032242)
0.4 5.7 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.4 10.6 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.4 21.0 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.4 2.6 GO:2000503 regulation of natural killer cell chemotaxis(GO:2000501) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.4 1.8 GO:0010918 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) positive regulation of mitochondrial membrane potential(GO:0010918)
0.4 1.1 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.4 5.4 GO:0071397 cellular response to cholesterol(GO:0071397)
0.4 5.3 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.4 2.1 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.3 2.8 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.3 13.4 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.3 4.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.3 2.0 GO:0098700 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.3 1.3 GO:0007296 vitellogenesis(GO:0007296)
0.3 1.0 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.3 3.0 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.3 5.5 GO:0021516 dorsal spinal cord development(GO:0021516)
0.3 2.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.3 3.3 GO:0015825 L-serine transport(GO:0015825)
0.3 9.2 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.3 7.7 GO:0030220 platelet formation(GO:0030220)
0.3 4.1 GO:0060315 negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.3 3.8 GO:0006559 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.3 1.4 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.3 2.2 GO:0006857 oligopeptide transport(GO:0006857)
0.3 4.0 GO:0031639 plasminogen activation(GO:0031639)
0.3 1.6 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.3 2.1 GO:0090527 actin filament reorganization(GO:0090527)
0.3 1.3 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.3 4.9 GO:0007567 parturition(GO:0007567)
0.3 4.9 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.3 2.3 GO:0035865 cellular response to potassium ion(GO:0035865)
0.2 4.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 1.7 GO:0055091 phospholipid homeostasis(GO:0055091)
0.2 3.3 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.2 2.6 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.2 3.2 GO:0033623 regulation of integrin activation(GO:0033623)
0.2 4.9 GO:0006825 copper ion transport(GO:0006825)
0.2 16.9 GO:0006968 cellular defense response(GO:0006968)
0.2 4.8 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.2 0.7 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 3.6 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.2 2.0 GO:0006477 protein sulfation(GO:0006477)
0.2 1.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.2 5.1 GO:0003334 keratinocyte development(GO:0003334)
0.2 2.4 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.2 3.2 GO:0051775 response to redox state(GO:0051775)
0.2 1.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.2 0.6 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.2 1.3 GO:0019532 oxalate transport(GO:0019532)
0.2 10.7 GO:0042073 intraciliary transport(GO:0042073)
0.2 2.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2 0.8 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.2 5.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 3.0 GO:0046697 decidualization(GO:0046697)
0.2 2.8 GO:0001771 immunological synapse formation(GO:0001771)
0.2 3.4 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.2 2.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.2 3.1 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.2 1.8 GO:0006501 C-terminal protein lipidation(GO:0006501) C-terminal protein amino acid modification(GO:0018410)
0.2 1.8 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.2 0.9 GO:0048852 hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852)
0.2 7.0 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.2 2.5 GO:0071285 cellular response to lithium ion(GO:0071285)
0.2 0.9 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.2 4.6 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.2 0.7 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.2 2.0 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.2 5.9 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.2 2.2 GO:0046415 urate metabolic process(GO:0046415)
0.2 2.8 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.2 9.2 GO:0070527 platelet aggregation(GO:0070527)
0.1 0.4 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.1 2.1 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 2.7 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 1.2 GO:0045953 response to yeast(GO:0001878) negative regulation of natural killer cell mediated cytotoxicity(GO:0045953)
0.1 4.3 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.1 1.0 GO:0051873 killing by host of symbiont cells(GO:0051873)
0.1 0.3 GO:0071503 response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
0.1 0.5 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 6.0 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.1 0.5 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.1 1.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 4.3 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.1 1.8 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.1 11.1 GO:0021987 cerebral cortex development(GO:0021987)
0.1 5.8 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.1 5.9 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 5.7 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 5.4 GO:0032760 positive regulation of tumor necrosis factor production(GO:0032760) positive regulation of tumor necrosis factor superfamily cytokine production(GO:1903557)
0.1 0.8 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.1 5.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 1.0 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 2.5 GO:0035966 response to topologically incorrect protein(GO:0035966)
0.1 13.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 2.0 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.2 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 7.6 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 3.7 GO:0060612 adipose tissue development(GO:0060612)
0.1 3.4 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 2.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 10.4 GO:0048839 inner ear development(GO:0048839)
0.1 1.3 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 1.7 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 0.2 GO:0072535 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) tumor necrosis factor (ligand) superfamily member 11 production(GO:0072535) positive regulation of bone mineralization involved in bone maturation(GO:1900159) regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000307) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.1 3.0 GO:0006505 GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.1 2.5 GO:0035904 aorta development(GO:0035904)
0.1 4.8 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.1 1.6 GO:0006853 carnitine shuttle(GO:0006853)
0.1 0.4 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 3.9 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.2 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.1 1.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 2.5 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 2.2 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 3.1 GO:0030154 cell differentiation(GO:0030154)
0.1 0.6 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.9 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 8.0 GO:0015992 proton transport(GO:0015992)
0.1 2.3 GO:0061053 somite development(GO:0061053)
0.1 1.8 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 0.2 GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.1 0.6 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.1 1.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 1.0 GO:0019682 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.1 3.8 GO:0007041 lysosomal transport(GO:0007041)
0.0 2.5 GO:0060563 neuroepithelial cell differentiation(GO:0060563)
0.0 2.1 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.7 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 1.3 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 1.4 GO:0009615 response to virus(GO:0009615)
0.0 0.1 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.0 2.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.6 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.0 2.7 GO:0030516 regulation of axon extension(GO:0030516)
0.0 0.2 GO:1904783 negative regulation of lamellipodium assembly(GO:0010593) regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) positive regulation of NMDA glutamate receptor activity(GO:1904783) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.1 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 15.8 GO:0016311 dephosphorylation(GO:0016311)
0.0 0.8 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 2.0 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.3 GO:0015871 choline transport(GO:0015871)
0.0 1.7 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 2.3 GO:0006094 gluconeogenesis(GO:0006094)
0.0 1.0 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 1.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.4 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 17.5 GO:0043623 cellular protein complex assembly(GO:0043623)
0.0 4.9 GO:0050890 cognition(GO:0050890)
0.0 0.6 GO:0007398 ectoderm development(GO:0007398)
0.0 2.6 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.6 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 2.4 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.4 GO:0050680 negative regulation of epithelial cell proliferation(GO:0050680)
0.0 1.3 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 6.5 GO:0006936 muscle contraction(GO:0006936)
0.0 1.7 GO:0007088 regulation of mitotic nuclear division(GO:0007088)
0.0 0.3 GO:0042692 muscle cell differentiation(GO:0042692)
0.0 1.2 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.7 GO:0008217 regulation of blood pressure(GO:0008217)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 1.4 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.1 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
9.8 39.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
8.1 137.7 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
5.0 25.1 GO:0098843 postsynaptic endocytic zone(GO:0098843)
3.7 11.1 GO:1990015 mesaxon(GO:0097453) ensheathing process(GO:1990015)
3.5 53.0 GO:0030478 actin cap(GO:0030478)
3.1 9.4 GO:0005588 collagen type V trimer(GO:0005588)
3.0 15.0 GO:0005602 complement component C1 complex(GO:0005602)
2.6 29.1 GO:0005614 interstitial matrix(GO:0005614)
2.4 33.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
2.3 39.1 GO:0043194 axon initial segment(GO:0043194)
2.1 10.7 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
2.1 14.4 GO:0032584 growth cone membrane(GO:0032584)
2.0 10.1 GO:0001652 granular component(GO:0001652)
1.8 29.0 GO:0097512 cardiac myofibril(GO:0097512)
1.8 7.0 GO:0031673 H zone(GO:0031673)
1.7 6.7 GO:0005965 protein farnesyltransferase complex(GO:0005965)
1.7 14.9 GO:0005579 membrane attack complex(GO:0005579)
1.5 6.1 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
1.5 4.4 GO:0016938 kinesin I complex(GO:0016938)
1.5 23.4 GO:0031089 platelet dense granule lumen(GO:0031089)
1.3 16.5 GO:0005577 fibrinogen complex(GO:0005577)
1.2 7.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
1.1 18.9 GO:0032059 bleb(GO:0032059)
1.0 8.4 GO:0045179 apical cortex(GO:0045179)
1.0 6.8 GO:0036021 endolysosome lumen(GO:0036021)
0.9 29.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.9 4.4 GO:0070847 core mediator complex(GO:0070847)
0.8 5.7 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.8 8.8 GO:0097443 sorting endosome(GO:0097443)
0.7 6.7 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.7 4.2 GO:0070435 Shc-EGFR complex(GO:0070435)
0.6 5.4 GO:0071953 elastic fiber(GO:0071953)
0.6 1.8 GO:0044609 DBIRD complex(GO:0044609)
0.6 10.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.5 3.8 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.5 7.8 GO:0042627 chylomicron(GO:0042627)
0.5 8.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.5 5.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.5 53.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.5 5.9 GO:0008385 IkappaB kinase complex(GO:0008385)
0.4 13.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.4 14.2 GO:1904115 axon cytoplasm(GO:1904115)
0.4 10.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.3 2.0 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.3 12.8 GO:0000421 autophagosome membrane(GO:0000421)
0.3 5.9 GO:0031045 dense core granule(GO:0031045)
0.3 3.1 GO:0033270 paranode region of axon(GO:0033270)
0.3 17.5 GO:0001772 immunological synapse(GO:0001772)
0.3 4.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.3 12.6 GO:0031672 A band(GO:0031672)
0.3 46.0 GO:0072562 blood microparticle(GO:0072562)
0.2 3.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.2 15.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 3.6 GO:0097225 sperm midpiece(GO:0097225)
0.2 3.2 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.2 114.1 GO:0005813 centrosome(GO:0005813)
0.2 13.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 2.1 GO:0008091 spectrin(GO:0008091)
0.2 1.9 GO:0002102 podosome(GO:0002102)
0.2 2.0 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.2 2.4 GO:0051233 spindle midzone(GO:0051233)
0.1 10.9 GO:0005581 collagen trimer(GO:0005581)
0.1 0.9 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 3.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 7.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 3.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 3.5 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 14.6 GO:0005882 intermediate filament(GO:0005882)
0.1 8.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 4.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 7.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 30.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 3.9 GO:0001533 cornified envelope(GO:0001533)
0.1 7.2 GO:0005811 lipid particle(GO:0005811)
0.1 5.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 2.5 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 1.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 5.7 GO:0030027 lamellipodium(GO:0030027)
0.1 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 1.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 13.8 GO:0097060 synaptic membrane(GO:0097060)
0.1 1.0 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 7.4 GO:0005901 caveola(GO:0005901)
0.1 2.5 GO:0009925 basal plasma membrane(GO:0009925)
0.1 6.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 0.2 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.1 5.0 GO:0016528 sarcoplasm(GO:0016528)
0.1 14.2 GO:0060076 excitatory synapse(GO:0060076)
0.1 0.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 5.8 GO:0030175 filopodium(GO:0030175)
0.1 1.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 1.8 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.7 GO:0042589 zymogen granule(GO:0042588) zymogen granule membrane(GO:0042589)
0.1 4.9 GO:0030018 Z disc(GO:0030018)
0.1 9.0 GO:0043209 myelin sheath(GO:0043209)
0.0 0.2 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 11.4 GO:0043235 receptor complex(GO:0043235)
0.0 2.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 7.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 2.8 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.6 GO:0030904 retromer complex(GO:0030904)
0.0 2.8 GO:0070382 exocytic vesicle(GO:0070382)
0.0 13.2 GO:0005925 focal adhesion(GO:0005925)
0.0 50.3 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 3.1 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.6 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.6 GO:0001726 ruffle(GO:0001726)
0.0 0.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.4 GO:0016235 aggresome(GO:0016235)
0.0 1.1 GO:0031012 extracellular matrix(GO:0031012)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
16.1 48.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
13.8 41.3 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
8.9 35.6 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
8.8 70.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
6.4 128.8 GO:0051787 misfolded protein binding(GO:0051787)
5.6 33.6 GO:0004522 ribonuclease A activity(GO:0004522)
2.7 10.9 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
2.6 7.8 GO:0017129 triglyceride binding(GO:0017129)
2.5 24.6 GO:0045545 syndecan binding(GO:0045545)
2.5 41.8 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
2.3 9.4 GO:0001855 complement component C4b binding(GO:0001855)
2.2 13.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
2.2 10.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.9 5.7 GO:0004157 dihydropyrimidinase activity(GO:0004157)
1.8 5.5 GO:0070538 oleic acid binding(GO:0070538)
1.8 23.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
1.8 5.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
1.8 10.7 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
1.7 6.7 GO:0004660 protein farnesyltransferase activity(GO:0004660)
1.6 19.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
1.5 9.0 GO:0030492 hemoglobin binding(GO:0030492)
1.5 6.0 GO:0001847 opsonin receptor activity(GO:0001847)
1.5 41.3 GO:0005523 tropomyosin binding(GO:0005523)
1.5 8.8 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
1.4 14.4 GO:0035727 lysophosphatidic acid binding(GO:0035727)
1.4 8.6 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
1.4 16.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
1.2 16.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
1.2 19.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
1.2 15.9 GO:0019957 C-C chemokine binding(GO:0019957)
1.2 7.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
1.1 5.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.9 6.6 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.9 3.8 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.9 29.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.9 8.3 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.9 5.4 GO:0004882 androgen receptor activity(GO:0004882)
0.9 10.8 GO:0042301 phosphate ion binding(GO:0042301)
0.9 11.2 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.8 2.5 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.8 5.7 GO:0097643 amylin receptor activity(GO:0097643)
0.8 10.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004) neurotrophin receptor activity(GO:0005030)
0.8 3.8 GO:0016882 cyclo-ligase activity(GO:0016882)
0.8 8.3 GO:0008061 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.8 2.3 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.8 6.0 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.7 10.5 GO:0033691 sialic acid binding(GO:0033691)
0.7 2.2 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.7 5.1 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.7 7.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.7 2.9 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.7 2.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.7 19.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.7 2.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.7 2.0 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.7 6.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.7 6.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.6 7.5 GO:0045159 myosin II binding(GO:0045159)
0.6 2.5 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.6 6.8 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.6 4.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.6 3.5 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.6 10.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.6 9.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.6 1.7 GO:0032093 SAM domain binding(GO:0032093)
0.6 2.8 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.5 4.9 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.5 2.1 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.5 1.6 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.5 13.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.5 2.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.5 2.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.5 45.4 GO:0005518 collagen binding(GO:0005518)
0.5 4.4 GO:0030331 estrogen receptor binding(GO:0030331)
0.5 2.4 GO:0004995 tachykinin receptor activity(GO:0004995)
0.5 2.8 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.4 4.4 GO:0003777 microtubule motor activity(GO:0003777)
0.4 3.5 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.4 3.0 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.4 2.5 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.4 5.7 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.4 4.0 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.4 10.3 GO:0004697 protein kinase C activity(GO:0004697)
0.4 3.5 GO:0005000 vasopressin receptor activity(GO:0005000)
0.4 18.7 GO:0030507 spectrin binding(GO:0030507)
0.4 2.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.4 4.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.4 4.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.3 3.5 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.3 1.3 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3 1.0 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057)
0.3 7.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.3 6.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.3 3.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.3 4.7 GO:0031005 filamin binding(GO:0031005)
0.3 30.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 3.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.3 6.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.3 6.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.3 2.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.3 1.1 GO:0070568 guanylyltransferase activity(GO:0070568)
0.3 2.5 GO:0008158 hedgehog receptor activity(GO:0008158)
0.3 2.6 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.3 4.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 3.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 7.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 5.9 GO:0005521 lamin binding(GO:0005521)
0.2 2.7 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.2 2.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2 4.2 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.2 1.7 GO:0004064 arylesterase activity(GO:0004064)
0.2 1.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 31.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 1.0 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.2 6.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2 1.6 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.2 1.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 1.9 GO:0015232 heme transporter activity(GO:0015232)
0.2 7.0 GO:0008009 chemokine activity(GO:0008009)
0.2 2.7 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 5.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 7.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.2 3.8 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.2 2.0 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 14.7 GO:0001618 virus receptor activity(GO:0001618)
0.2 1.9 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 2.6 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.2 0.9 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.2 5.9 GO:0042056 chemoattractant activity(GO:0042056)
0.2 2.6 GO:0097109 neuroligin family protein binding(GO:0097109)
0.2 1.7 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.2 7.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 1.7 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 3.4 GO:0042166 acetylcholine binding(GO:0042166)
0.1 16.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.8 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 4.8 GO:0030552 cAMP binding(GO:0030552)
0.1 3.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 1.0 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181) 5.8S rRNA binding(GO:1990932)
0.1 0.7 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 0.5 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.1 4.1 GO:0005504 fatty acid binding(GO:0005504)
0.1 10.9 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 2.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 2.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 8.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 10.3 GO:0008201 heparin binding(GO:0008201)
0.1 3.3 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 1.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 9.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 3.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 3.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 1.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 1.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 4.6 GO:0050681 androgen receptor binding(GO:0050681)
0.1 12.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.2 GO:0070513 death domain binding(GO:0070513)
0.1 3.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 1.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 3.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.6 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.9 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 1.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 6.1 GO:0005178 integrin binding(GO:0005178)
0.1 0.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 16.2 GO:0005096 GTPase activator activity(GO:0005096)
0.1 10.6 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 42.8 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.1 0.5 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.3 GO:0039552 RIG-I binding(GO:0039552)
0.0 10.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.1 GO:1990939 ATP-dependent microtubule motor activity(GO:1990939)
0.0 14.8 GO:0003712 transcription cofactor activity(GO:0003712)
0.0 2.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 19.5 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 1.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 6.0 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.3 GO:0031433 telethonin binding(GO:0031433)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 3.2 GO:0005543 phospholipid binding(GO:0005543)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 41.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
1.1 75.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.8 20.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.8 6.4 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.8 54.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.8 41.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.8 101.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.7 10.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.6 39.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.6 8.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.5 7.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.4 7.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.4 5.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.4 1.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.4 15.2 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.4 63.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.4 13.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.4 13.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.3 74.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.3 14.7 ST GA13 PATHWAY G alpha 13 Pathway
0.3 7.2 PID RAS PATHWAY Regulation of Ras family activation
0.3 8.1 PID IL23 PATHWAY IL23-mediated signaling events
0.3 7.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 9.4 NABA COLLAGENS Genes encoding collagen proteins
0.2 5.6 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.2 11.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 9.9 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.2 15.2 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.2 10.1 PID SHP2 PATHWAY SHP2 signaling
0.2 5.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.2 1.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 5.3 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.2 4.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.2 6.8 PID FGF PATHWAY FGF signaling pathway
0.2 5.9 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.2 1.5 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.2 4.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 10.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 13.7 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 8.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 2.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.0 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 2.3 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 0.9 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 30.1 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.1 1.6 PID IL1 PATHWAY IL1-mediated signaling events
0.1 7.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 1.8 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 1.8 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 2.5 PID AP1 PATHWAY AP-1 transcription factor network
0.0 2.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.3 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.1 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 43.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
2.2 24.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
1.9 23.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
1.7 107.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
1.2 33.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
1.2 21.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
1.1 35.0 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
1.1 142.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
1.0 34.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.8 19.1 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.8 17.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.8 8.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.6 35.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.6 3.5 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.5 9.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.4 53.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.4 5.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.4 6.8 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.4 13.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.4 3.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.4 14.2 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.4 9.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.4 7.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.3 2.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.3 11.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.3 62.7 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.3 4.0 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.3 2.9 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.3 6.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.3 1.8 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.3 6.5 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.2 9.7 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.2 6.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 2.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.2 3.8 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 6.5 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.2 4.9 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 3.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 3.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 2.5 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.2 3.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.2 4.2 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.2 9.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.2 9.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 7.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 3.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 5.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.2 3.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 4.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.2 2.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 2.9 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 13.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 8.9 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.1 2.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 2.5 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 8.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 4.1 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 1.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 2.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 2.0 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 3.6 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 3.0 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.1 2.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 2.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 3.6 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.1 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 2.0 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.1 0.6 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 1.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.6 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.1 1.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.6 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 2.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 2.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 3.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.4 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 1.8 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells