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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for STAT6

Z-value: 0.70

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Transcription factors associated with STAT6

Gene Symbol Gene ID Gene Info
STAT6
ENSG00000166888.6 signal transducer and activator of transcription 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT6hg19_v2_chr12_-_57505121_575052160.283.5e-05Click!

Activity profile of STAT6 motif

Sorted Z-values of STAT6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_30075463 13.49 ENST00000562168.1
ENST00000569545.1
ALDOA
aldolase A, fructose-bisphosphate
chr16_+_30075595 13.14 ENST00000563060.2
ALDOA
aldolase A, fructose-bisphosphate
chr16_+_30075783 12.44 ENST00000412304.2
ALDOA
aldolase A, fructose-bisphosphate
chr14_-_69446034 12.40 ENST00000193403.6
ACTN1
actinin, alpha 1
chr11_-_14379997 11.32 ENST00000526063.1
ENST00000532814.1
RRAS2
related RAS viral (r-ras) oncogene homolog 2
chr5_+_102201722 9.94 ENST00000274392.9
ENST00000455264.2
PAM
peptidylglycine alpha-amidating monooxygenase
chr1_-_68299130 9.69 ENST00000370982.3
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr5_+_74011328 7.59 ENST00000513336.1
HEXB
hexosaminidase B (beta polypeptide)
chr1_-_209824643 6.27 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr1_-_108735440 5.90 ENST00000370041.4
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chrX_+_135251783 5.84 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr12_-_6451235 5.62 ENST00000440083.2
ENST00000162749.2
TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr17_-_39681578 5.59 ENST00000593096.1
KRT19
keratin 19
chr6_+_32821924 5.49 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr3_+_158787041 5.39 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr5_+_118691706 5.35 ENST00000415806.2
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr22_+_44464923 5.12 ENST00000404989.1
PARVB
parvin, beta
chr21_+_42539701 5.02 ENST00000330333.6
ENST00000328735.6
ENST00000347667.5
BACE2
beta-site APP-cleaving enzyme 2
chr2_-_190044480 4.96 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr8_+_97506033 4.77 ENST00000518385.1
SDC2
syndecan 2
chr3_+_158991025 4.66 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chrX_+_135251835 4.64 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr17_+_34640031 4.55 ENST00000339270.6
ENST00000482104.1
CCL4L2
chemokine (C-C motif) ligand 4-like 2
chr17_+_34538310 4.53 ENST00000444414.1
ENST00000378350.4
ENST00000389068.5
ENST00000588929.1
ENST00000589079.1
ENST00000589336.1
ENST00000400702.4
ENST00000591167.1
ENST00000586598.1
ENST00000591637.1
ENST00000378352.4
ENST00000358756.5
CCL4L1
chemokine (C-C motif) ligand 4-like 1
chr2_+_120124497 4.52 ENST00000355857.3
ENST00000535617.1
ENST00000535757.1
ENST00000409094.1
ENST00000311521.4
DBI
diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr8_+_9953214 4.40 ENST00000382490.5
MSRA
methionine sulfoxide reductase A
chr8_+_9953061 4.37 ENST00000522907.1
ENST00000528246.1
MSRA
methionine sulfoxide reductase A
chr15_+_89402148 4.32 ENST00000560601.1
ACAN
aggrecan
chrX_+_135252050 4.32 ENST00000449474.1
ENST00000345434.3
FHL1
four and a half LIM domains 1
chr6_-_24877490 4.22 ENST00000540914.1
ENST00000378023.4
FAM65B
family with sequence similarity 65, member B
chr14_+_56127989 4.18 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chr1_-_241803679 4.10 ENST00000331838.5
OPN3
opsin 3
chrX_+_100878079 4.05 ENST00000471229.2
ARMCX3
armadillo repeat containing, X-linked 3
chr3_-_185655795 3.85 ENST00000342294.4
ENST00000382191.4
ENST00000453386.2
TRA2B
transformer 2 beta homolog (Drosophila)
chr15_+_96869165 3.85 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr6_-_11232891 3.74 ENST00000379433.5
ENST00000379446.5
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr17_+_34639793 3.64 ENST00000394465.2
ENST00000394463.2
ENST00000378342.4
CCL4L2
chemokine (C-C motif) ligand 4-like 2
chr1_+_89246647 3.59 ENST00000544045.1
PKN2
protein kinase N2
chr7_-_76829125 3.46 ENST00000248598.5
FGL2
fibrinogen-like 2
chr11_-_10828892 3.29 ENST00000525681.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr8_+_104311059 3.27 ENST00000358755.4
ENST00000523739.1
ENST00000540287.1
FZD6
frizzled family receptor 6
chr2_-_230786619 3.26 ENST00000389045.3
ENST00000409677.1
TRIP12
thyroid hormone receptor interactor 12
chr14_-_23285011 3.26 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr10_-_65028817 3.23 ENST00000542921.1
JMJD1C
jumonji domain containing 1C
chr11_+_118230287 3.23 ENST00000252108.3
ENST00000431736.2
UBE4A
ubiquitination factor E4A
chr9_+_36572851 3.21 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
MELK
maternal embryonic leucine zipper kinase
chr12_+_56435637 3.17 ENST00000356464.5
ENST00000552361.1
RPS26
ribosomal protein S26
chr6_-_32821599 3.17 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr12_-_111358372 3.17 ENST00000548438.1
ENST00000228841.8
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chrX_-_106960285 3.11 ENST00000503515.1
ENST00000372397.2
TSC22D3
TSC22 domain family, member 3
chr14_-_23285069 2.99 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr20_-_23066953 2.97 ENST00000246006.4
CD93
CD93 molecule
chr4_-_120988229 2.97 ENST00000296509.6
MAD2L1
MAD2 mitotic arrest deficient-like 1 (yeast)
chr1_+_114472481 2.94 ENST00000369555.2
HIPK1
homeodomain interacting protein kinase 1
chr1_+_114472222 2.75 ENST00000369558.1
ENST00000369561.4
HIPK1
homeodomain interacting protein kinase 1
chr17_+_7462103 2.75 ENST00000396545.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr5_+_140602904 2.66 ENST00000515856.2
ENST00000239449.4
PCDHB14
protocadherin beta 14
chr11_-_60719213 2.60 ENST00000227880.3
SLC15A3
solute carrier family 15 (oligopeptide transporter), member 3
chr3_-_49851313 2.58 ENST00000333486.3
UBA7
ubiquitin-like modifier activating enzyme 7
chr8_+_11666649 2.50 ENST00000528643.1
ENST00000525777.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr17_-_34207295 2.43 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr2_+_182756615 2.43 ENST00000431877.2
ENST00000320370.7
SSFA2
sperm specific antigen 2
chr17_+_34431212 2.36 ENST00000394495.1
CCL4
chemokine (C-C motif) ligand 4
chr8_-_117886955 2.28 ENST00000297338.2
RAD21
RAD21 homolog (S. pombe)
chr17_+_7462031 2.20 ENST00000380535.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr12_+_123949053 2.15 ENST00000350887.5
SNRNP35
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr7_-_38305279 2.03 ENST00000443402.2
TRGC1
T cell receptor gamma constant 1
chr14_-_25103388 2.03 ENST00000526004.1
ENST00000415355.3
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr3_+_179370517 2.02 ENST00000263966.3
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr1_-_241683001 1.97 ENST00000366560.3
FH
fumarate hydratase
chr1_-_120935894 1.96 ENST00000369383.4
ENST00000369384.4
FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
chr16_-_73093597 1.95 ENST00000397992.5
ZFHX3
zinc finger homeobox 3
chr17_+_68071389 1.94 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr1_+_149754227 1.90 ENST00000444948.1
ENST00000369168.4
FCGR1A
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr2_+_68961905 1.87 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr5_+_35856951 1.86 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R
interleukin 7 receptor
chr12_+_12764773 1.86 ENST00000228865.2
CREBL2
cAMP responsive element binding protein-like 2
chr11_+_112832133 1.82 ENST00000524665.1
NCAM1
neural cell adhesion molecule 1
chr2_+_68961934 1.79 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr11_-_67980744 1.79 ENST00000401547.2
ENST00000453170.1
ENST00000304363.4
SUV420H1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr9_+_90112117 1.75 ENST00000358077.5
DAPK1
death-associated protein kinase 1
chr22_-_42342692 1.74 ENST00000404067.1
ENST00000402338.1
CENPM
centromere protein M
chr18_-_24445664 1.74 ENST00000578776.1
AQP4
aquaporin 4
chr6_+_26440700 1.72 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3
butyrophilin, subfamily 3, member A3
chr5_+_138609441 1.68 ENST00000509990.1
ENST00000506147.1
ENST00000512107.1
MATR3
matrin 3
chr17_+_7461613 1.65 ENST00000438470.1
ENST00000436057.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr17_+_7461781 1.60 ENST00000349228.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr17_+_7461849 1.50 ENST00000338784.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr8_+_123793633 1.49 ENST00000314393.4
ZHX2
zinc fingers and homeoboxes 2
chr17_+_7461580 1.48 ENST00000483039.1
ENST00000396542.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr2_-_133427767 1.47 ENST00000397463.2
LYPD1
LY6/PLAUR domain containing 1
chr22_-_42343117 1.47 ENST00000407253.3
ENST00000215980.5
CENPM
centromere protein M
chr14_-_25103472 1.46 ENST00000216341.4
ENST00000382542.1
ENST00000382540.1
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr14_-_25078864 1.33 ENST00000216338.4
ENST00000557220.2
ENST00000382548.4
GZMH
granzyme H (cathepsin G-like 2, protein h-CCPX)
chr10_+_115674530 1.33 ENST00000451472.1
AL162407.1
CDNA FLJ20147 fis, clone COL07954; HCG1781466; Uncharacterized protein
chr15_+_25200074 1.32 ENST00000390687.4
ENST00000584968.1
ENST00000346403.6
ENST00000554227.2
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr11_+_65101225 1.29 ENST00000528416.1
ENST00000415073.2
ENST00000252268.4
DPF2
D4, zinc and double PHD fingers family 2
chr15_+_25200108 1.29 ENST00000577949.1
ENST00000338094.6
ENST00000338327.4
ENST00000579070.1
ENST00000577565.1
SNURF
SNRPN
SNRPN upstream reading frame protein
small nuclear ribonucleoprotein polypeptide N
chr9_+_90112741 1.29 ENST00000469640.2
DAPK1
death-associated protein kinase 1
chr22_-_31364187 1.23 ENST00000215862.4
ENST00000397641.3
MORC2
MORC family CW-type zinc finger 2
chr2_-_16804320 1.20 ENST00000355549.2
FAM49A
family with sequence similarity 49, member A
chr7_-_150777949 1.18 ENST00000482571.1
FASTK
Fas-activated serine/threonine kinase
chr1_-_147245445 1.17 ENST00000430508.1
GJA5
gap junction protein, alpha 5, 40kDa
chr4_-_110723134 1.11 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr7_-_150777920 1.11 ENST00000353841.2
ENST00000297532.6
FASTK
Fas-activated serine/threonine kinase
chr1_+_150245099 1.06 ENST00000369099.3
C1orf54
chromosome 1 open reading frame 54
chr12_+_6493199 1.06 ENST00000228918.4
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr2_+_27440229 0.95 ENST00000264705.4
ENST00000403525.1
CAD
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr15_+_64386261 0.93 ENST00000560829.1
SNX1
sorting nexin 1
chr9_+_90112767 0.92 ENST00000408954.3
DAPK1
death-associated protein kinase 1
chr4_+_30721968 0.82 ENST00000361762.2
PCDH7
protocadherin 7
chr19_+_38924316 0.81 ENST00000355481.4
ENST00000360985.3
ENST00000359596.3
RYR1
ryanodine receptor 1 (skeletal)
chr7_-_150777874 0.77 ENST00000540185.1
FASTK
Fas-activated serine/threonine kinase
chr14_+_38677123 0.76 ENST00000267377.2
SSTR1
somatostatin receptor 1
chr3_-_57233966 0.75 ENST00000473921.1
ENST00000295934.3
HESX1
HESX homeobox 1
chr9_+_90112590 0.74 ENST00000472284.1
DAPK1
death-associated protein kinase 1
chr2_+_191792376 0.73 ENST00000409428.1
ENST00000409215.1
GLS
glutaminase
chr1_-_116383322 0.71 ENST00000429731.1
NHLH2
nescient helix loop helix 2
chr11_-_72463421 0.63 ENST00000393609.3
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr1_+_12123414 0.63 ENST00000263932.2
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr1_-_94586651 0.53 ENST00000535735.1
ENST00000370225.3
ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
chr5_-_88119580 0.51 ENST00000539796.1
MEF2C
myocyte enhancer factor 2C
chr1_+_32608566 0.48 ENST00000545542.1
KPNA6
karyopherin alpha 6 (importin alpha 7)
chr12_-_71031185 0.47 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB
protein tyrosine phosphatase, receptor type, B
chr17_-_17740287 0.39 ENST00000355815.4
ENST00000261646.5
SREBF1
sterol regulatory element binding transcription factor 1
chr11_-_128457446 0.38 ENST00000392668.4
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr5_+_102201687 0.37 ENST00000304400.7
PAM
peptidylglycine alpha-amidating monooxygenase
chr7_-_122840015 0.34 ENST00000194130.2
SLC13A1
solute carrier family 13 (sodium/sulfate symporter), member 1
chr4_-_186877806 0.34 ENST00000355634.5
SORBS2
sorbin and SH3 domain containing 2
chr3_-_120365866 0.33 ENST00000475447.2
HGD
homogentisate 1,2-dioxygenase
chr3_+_63898275 0.33 ENST00000538065.1
ATXN7
ataxin 7
chr11_+_7618413 0.29 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr4_-_46391931 0.29 ENST00000381620.4
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr7_+_55433131 0.29 ENST00000254770.2
LANCL2
LanC lantibiotic synthetase component C-like 2 (bacterial)
chr3_+_51575596 0.25 ENST00000409535.2
RAD54L2
RAD54-like 2 (S. cerevisiae)
chr2_+_234526272 0.24 ENST00000373450.4
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr19_+_2785458 0.21 ENST00000307741.6
ENST00000585338.1
THOP1
thimet oligopeptidase 1
chr6_-_41254403 0.21 ENST00000589614.1
ENST00000334475.6
ENST00000591620.1
ENST00000244709.4
TREM1
triggering receptor expressed on myeloid cells 1
chr1_-_190446759 0.19 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr4_+_71337834 0.18 ENST00000304887.5
MUC7
mucin 7, secreted
chr12_+_15125954 0.17 ENST00000266395.2
PDE6H
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr9_-_13175823 0.15 ENST00000545857.1
MPDZ
multiple PDZ domain protein
chr11_+_65082289 0.11 ENST00000279249.2
CDC42EP2
CDC42 effector protein (Rho GTPase binding) 2
chr7_+_138818490 0.09 ENST00000430935.1
ENST00000495038.1
ENST00000474035.2
ENST00000478836.2
ENST00000464848.1
ENST00000343187.4
TTC26
tetratricopeptide repeat domain 26
chr13_+_73629107 0.07 ENST00000539231.1
KLF5
Kruppel-like factor 5 (intestinal)
chr10_-_35379524 0.05 ENST00000374751.3
ENST00000374742.1
ENST00000602371.1
CUL2
cullin 2
chr14_+_22520762 0.04 ENST00000390449.3
TRAV21
T cell receptor alpha variable 21
chr1_-_116383738 0.03 ENST00000320238.3
NHLH2
nescient helix loop helix 2
chr4_-_46391805 0.02 ENST00000540012.1
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 10.3 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
2.2 39.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.5 7.6 GO:0007619 courtship behavior(GO:0007619)
1.2 5.0 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
1.0 6.2 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
1.0 8.8 GO:0030091 protein repair(GO:0030091)
1.0 3.8 GO:0021796 cerebral cortex regionalization(GO:0021796)
1.0 3.8 GO:0009956 radial pattern formation(GO:0009956)
0.9 11.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.8 3.3 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.8 3.2 GO:0046967 cytosol to ER transport(GO:0046967)
0.8 12.4 GO:0051639 actin filament network formation(GO:0051639)
0.7 5.9 GO:0015866 ADP transport(GO:0015866)
0.7 5.1 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.7 4.8 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.7 4.8 GO:0008218 bioluminescence(GO:0008218)
0.7 2.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.6 5.7 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.6 5.0 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.5 5.6 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.5 2.0 GO:0035523 protein K29-linked deubiquitination(GO:0035523) maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.5 2.5 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.5 3.5 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.5 1.9 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.5 3.3 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.4 3.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.4 3.1 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.4 2.3 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.3 3.0 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.3 2.6 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.3 0.9 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.3 4.5 GO:0018345 protein palmitoylation(GO:0018345)
0.3 4.7 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.3 4.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.3 14.8 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.3 4.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.2 0.7 GO:0098904 pulmonary valve formation(GO:0003193) atrial ventricular junction remodeling(GO:0003294) foramen ovale closure(GO:0035922) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of AV node cell action potential(GO:0098904) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
0.2 6.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 0.6 GO:0032679 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.2 9.7 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.2 1.9 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.2 0.6 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.2 3.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.2 0.8 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 5.6 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.1 0.7 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.8 GO:0071313 cellular response to caffeine(GO:0071313)
0.1 0.5 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 9.4 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.1 4.3 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 2.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 3.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 3.2 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.1 0.9 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.7 GO:0030916 otic vesicle formation(GO:0030916)
0.1 1.7 GO:0003091 renal water homeostasis(GO:0003091)
0.1 1.5 GO:1905145 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 1.8 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 0.4 GO:0030578 PML body organization(GO:0030578)
0.1 1.9 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 3.2 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.0 0.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 3.2 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 3.3 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.7 GO:0044705 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.4 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 4.8 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 1.9 GO:0046889 positive regulation of lipid biosynthetic process(GO:0046889)
0.0 1.1 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 3.0 GO:0042116 macrophage activation(GO:0042116)
0.0 0.3 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.2 GO:0072672 neutrophil mediated killing of gram-negative bacterium(GO:0070945) neutrophil extravasation(GO:0072672)
0.0 0.3 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 0.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 3.7 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.1 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 3.1 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.5 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 8.0 GO:0030335 positive regulation of cell migration(GO:0030335)
0.0 0.3 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 3.1 GO:0007018 microtubule-based movement(GO:0007018)
0.0 2.2 GO:0015992 proton transport(GO:0015992)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0005588 collagen type V trimer(GO:0005588)
0.9 5.6 GO:1990357 terminal web(GO:1990357)
0.8 12.4 GO:0005916 fascia adherens(GO:0005916)
0.8 6.3 GO:0005610 laminin-5 complex(GO:0005610)
0.8 39.1 GO:0031430 M band(GO:0031430)
0.7 5.5 GO:1990111 spermatoproteasome complex(GO:1990111)
0.6 3.2 GO:0097512 cardiac myofibril(GO:0097512)
0.6 2.3 GO:0000798 nuclear cohesin complex(GO:0000798)
0.5 3.2 GO:0042825 TAP complex(GO:0042825)
0.3 3.5 GO:0005577 fibrinogen complex(GO:0005577)
0.2 0.8 GO:0030314 junctional membrane complex(GO:0030314)
0.2 2.6 GO:0005687 U4 snRNP(GO:0005687)
0.2 9.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 2.2 GO:0000243 commitment complex(GO:0000243)
0.2 0.9 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 3.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 4.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 2.0 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.1 3.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 16.7 GO:0043202 lysosomal lumen(GO:0043202)
0.1 3.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 5.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.2 GO:0097679 other organism cytoplasm(GO:0097679)
0.1 5.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 3.6 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 3.9 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 8.6 GO:0043204 perikaryon(GO:0043204)
0.1 35.3 GO:0005925 focal adhesion(GO:0005925)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 4.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 3.0 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 2.0 GO:0001772 immunological synapse(GO:0001772)
0.0 5.7 GO:0016605 PML body(GO:0016605)
0.0 0.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.3 GO:0030141 secretory granule(GO:0030141)
0.0 8.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 8.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 5.6 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.9 GO:0043195 terminal bouton(GO:0043195)
0.0 0.0 GO:0030891 VCB complex(GO:0030891)
0.0 3.8 GO:0005759 mitochondrial matrix(GO:0005759)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 39.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
2.6 10.3 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
1.8 8.8 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
1.1 5.6 GO:0043120 tumor necrosis factor binding(GO:0043120)
1.0 3.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.9 7.6 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.9 2.6 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.8 9.7 GO:0042301 phosphate ion binding(GO:0042301)
0.7 5.9 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
0.7 4.8 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.7 2.0 GO:1904288 BAT3 complex binding(GO:1904288)
0.6 2.5 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.6 1.9 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.6 6.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.5 3.2 GO:0046979 TAP2 binding(GO:0046979)
0.5 12.4 GO:0017166 vinculin binding(GO:0017166)
0.5 4.5 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.4 2.6 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.4 4.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.4 3.0 GO:0001849 complement component C1q binding(GO:0001849)
0.3 3.1 GO:0043426 MRF binding(GO:0043426)
0.3 0.9 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.2 2.0 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.2 1.5 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.2 0.7 GO:0086076 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.2 3.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 5.0 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.2 0.8 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.2 9.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 3.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 3.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 0.9 GO:1990460 leptin receptor binding(GO:1990460)
0.2 5.5 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 1.9 GO:0019864 IgG binding(GO:0019864)
0.2 0.8 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 4.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 4.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.7 GO:0004359 glutaminase activity(GO:0004359)
0.1 3.6 GO:0004697 protein kinase C activity(GO:0004697)
0.1 4.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 5.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 2.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 3.8 GO:0070717 poly-purine tract binding(GO:0070717)
0.1 1.7 GO:0015250 water channel activity(GO:0015250)
0.1 4.1 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.4 GO:0032810 sterol response element binding(GO:0032810)
0.1 14.8 GO:0044325 ion channel binding(GO:0044325)
0.1 3.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 5.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 3.0 GO:0019894 kinesin binding(GO:0019894)
0.1 1.7 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 5.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 4.8 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.3 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.6 GO:0031701 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 3.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 2.2 GO:0017069 snRNA binding(GO:0017069)
0.0 3.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 2.0 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.5 GO:0035198 miRNA binding(GO:0035198)
0.0 8.6 GO:0003924 GTPase activity(GO:0003924)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 5.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 3.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 2.4 GO:0051015 actin filament binding(GO:0051015)
0.0 0.3 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.4 GO:0035035 histone acetyltransferase binding(GO:0035035)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 39.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.3 14.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.3 6.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 3.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 6.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 3.9 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 3.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 5.0 NABA COLLAGENS Genes encoding collagen proteins
0.1 4.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 4.8 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 6.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 4.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 5.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 3.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 21.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.9 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.8 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.9 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 3.5 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 1.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.9 ST FAS SIGNALING PATHWAY Fas Signaling Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 39.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.7 11.9 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.6 17.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.4 9.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.4 4.1 REACTOME OPSINS Genes involved in Opsins
0.3 4.7 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 4.8 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.2 5.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 3.2 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.2 6.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 11.2 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1 9.4 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 1.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 3.0 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1 1.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.9 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 2.0 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 2.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 3.5 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 5.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 4.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 5.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 5.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 2.6 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 3.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 4.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 3.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 3.6 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.7 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 3.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 5.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.9 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 3.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport