GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
T Links Ensembl NCBI GeneCards UniProt	ENSG00000164458.5	T

Gene	Promoter	Pearson corr. coef.	P-value	Plot
T	hg19_v2_chr6_-_166582107_166582188	-0.43	3.6e-11	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr1_-_24126023 Show fit	47.24	ENST00000429356.1	GALE Links Ensembl NCBI GeneCards UniProt Show fit	UDP-galactose-4-epimerase
chr2_-_85636928 Show fit	20.34	ENST00000449030.1	CAPG Links Ensembl NCBI GeneCards UniProt Show fit	capping protein (actin filament), gelsolin-like
chr9_+_36572851 Show fit	19.35	ENST00000298048.2 ENST00000538311.1 ENST00000536987.1 ENST00000545008.1 ENST00000536860.1 ENST00000536329.1 ENST00000541717.1 ENST00000543751.1	MELK Links Ensembl NCBI GeneCards UniProt Show fit	maternal embryonic leucine zipper kinase
chr2_-_152146385 Show fit	19.23	ENST00000414946.1 ENST00000243346.5	NMI Links Ensembl NCBI GeneCards UniProt Show fit	N-myc (and STAT) interactor
chr3_+_133502877 Show fit	18.77	ENST00000466490.2	SRPRB Links Ensembl NCBI GeneCards UniProt Show fit	signal recognition particle receptor, B subunit
chrX_+_133594168 Show fit	15.22	ENST00000298556.7	HPRT1 Links Ensembl NCBI GeneCards UniProt Show fit	hypoxanthine phosphoribosyltransferase 1
chr15_+_78832747 Show fit	14.94	ENST00000560217.1 ENST00000044462.7 ENST00000559082.1 ENST00000559948.1 ENST00000413382.2 ENST00000559146.1 ENST00000558281.1	PSMA4 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome (prosome, macropain) subunit, alpha type, 4
chr16_-_88717423 Show fit	14.07	ENST00000568278.1 ENST00000569359.1 ENST00000567174.1	CYBA Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome b-245, alpha polypeptide
chr20_+_1115821 Show fit	12.94	ENST00000435720.1	PSMF1 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr20_+_1093891 Show fit	12.23	ENST00000333082.3 ENST00000381898.4 ENST00000381899.4	PSMF1 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr9_+_131452239 Show fit	11.63	ENST00000372688.4 ENST00000372686.5	SET Links Ensembl NCBI GeneCards UniProt Show fit	SET nuclear oncogene
chr17_-_26662440 Show fit	11.36	ENST00000578122.1	IFT20 Links Ensembl NCBI GeneCards UniProt Show fit	intraflagellar transport 20 homolog (Chlamydomonas)
chr16_+_69221028 Show fit	11.27	ENST00000336278.4	SNTB2 Links Ensembl NCBI GeneCards UniProt Show fit	syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr3_+_142315225 Show fit	11.11	ENST00000457734.2 ENST00000483373.1 ENST00000475296.1 ENST00000495744.1 ENST00000476044.1 ENST00000461644.1	PLS1 Links Ensembl NCBI GeneCards UniProt Show fit	plastin 1
chr5_-_112257914 Show fit	10.80	ENST00000513339.1 ENST00000545426.1 ENST00000504247.1	REEP5 Links Ensembl NCBI GeneCards UniProt Show fit	receptor accessory protein 5
chr20_+_34129770 Show fit	10.51	ENST00000348547.2 ENST00000357394.4 ENST00000447986.1 ENST00000279052.6 ENST00000416206.1 ENST00000411577.1 ENST00000413587.1	ERGIC3 Links Ensembl NCBI GeneCards UniProt Show fit	ERGIC and golgi 3
chr17_-_40306934 Show fit	10.20	ENST00000592574.1 ENST00000550406.1 ENST00000547517.1 ENST00000393860.3 ENST00000346213.4	CTD-2132N18.3 Links Ensembl NCBI GeneCards UniProt Show fit RAB5C Links Ensembl NCBI GeneCards UniProt Show fit	Uncharacterized protein RAB5C, member RAS oncogene family
chr6_+_83073334 Show fit	10.18	ENST00000369750.3	TPBG Links Ensembl NCBI GeneCards UniProt Show fit	trophoblast glycoprotein
chr2_+_58134756 Show fit	10.03	ENST00000435505.2 ENST00000417641.2	VRK2 Links Ensembl NCBI GeneCards UniProt Show fit	vaccinia related kinase 2
chr10_-_97050777 Show fit	9.92	ENST00000329399.6	PDLIM1 Links Ensembl NCBI GeneCards UniProt Show fit	PDZ and LIM domain 1
chr9_-_75567962 Show fit	9.66	ENST00000297785.3 ENST00000376939.1	ALDH1A1 Links Ensembl NCBI GeneCards UniProt Show fit	aldehyde dehydrogenase 1 family, member A1
chr12_-_56709674 Show fit	9.38	ENST00000551286.1 ENST00000549318.1	CNPY2 Links Ensembl NCBI GeneCards UniProt Show fit RP11-977G19.10 Links Ensembl NCBI GeneCards UniProt Show fit	canopy FGF signaling regulator 2 Uncharacterized protein
chr21_+_30502806 Show fit	9.13	ENST00000399928.1 ENST00000399926.1	MAP3K7CL Links Ensembl NCBI GeneCards UniProt Show fit	MAP3K7 C-terminal like
chr19_-_10514184 Show fit	9.02	ENST00000589629.1 ENST00000222005.2	CDC37 Links Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 37
chr16_-_88717482 Show fit	8.97	ENST00000261623.3	CYBA Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome b-245, alpha polypeptide
chr12_-_56710118 Show fit	8.91	ENST00000273308.4	CNPY2 Links Ensembl NCBI GeneCards UniProt Show fit	canopy FGF signaling regulator 2
chr12_-_6960407 Show fit	8.62	ENST00000540683.1 ENST00000229265.6 ENST00000535406.1 ENST00000422785.3	CDCA3 Links Ensembl NCBI GeneCards UniProt Show fit	cell division cycle associated 3
chr1_-_211752073 Show fit	8.28	ENST00000367001.4	SLC30A1 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 30 (zinc transporter), member 1
chr2_+_122494676 Show fit	8.12	ENST00000455432.1	TSN Links Ensembl NCBI GeneCards UniProt Show fit	translin
chr1_+_114471972 Show fit	8.08	ENST00000369559.4 ENST00000369554.2	HIPK1 Links Ensembl NCBI GeneCards UniProt Show fit	homeodomain interacting protein kinase 1
chr1_-_115124257 Show fit	7.62	ENST00000369541.3	BCAS2 Links Ensembl NCBI GeneCards UniProt Show fit	breast carcinoma amplified sequence 2
chr7_+_107220660 Show fit	6.85	ENST00000465919.1 ENST00000445771.2 ENST00000479917.1 ENST00000421217.1 ENST00000457837.1	BCAP29 Links Ensembl NCBI GeneCards UniProt Show fit	B-cell receptor-associated protein 29
chr19_-_44174330 Show fit	6.72	ENST00000340093.3	PLAUR Links Ensembl NCBI GeneCards UniProt Show fit	plasminogen activator, urokinase receptor
chr2_-_200322723 Show fit	6.40	ENST00000417098.1	SATB2 Links Ensembl NCBI GeneCards UniProt Show fit	SATB homeobox 2
chr17_+_34538310 Show fit	6.39	ENST00000444414.1 ENST00000378350.4 ENST00000389068.5 ENST00000588929.1 ENST00000589079.1 ENST00000589336.1 ENST00000400702.4 ENST00000591167.1 ENST00000586598.1 ENST00000591637.1 ENST00000378352.4 ENST00000358756.5	CCL4L1 Links Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-C motif) ligand 4-like 1
chr20_+_3190006 Show fit	6.22	ENST00000380113.3 ENST00000455664.2 ENST00000399838.3	ITPA Links Ensembl NCBI GeneCards UniProt Show fit	inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
chr12_+_19358228 Show fit	6.19	ENST00000424268.1 ENST00000543806.1	PLEKHA5 Links Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology domain containing, family A member 5
chr16_-_2314222 Show fit	6.13	ENST00000566397.1	RNPS1 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding protein S1, serine-rich domain
chr10_+_5488564 Show fit	6.06	ENST00000449083.1 ENST00000380359.3	NET1 Links Ensembl NCBI GeneCards UniProt Show fit	neuroepithelial cell transforming 1
chr11_-_85779971 Show fit	6.05	ENST00000393346.3	PICALM Links Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol binding clathrin assembly protein
chr17_-_56084578 Show fit	5.94	ENST00000582730.2 ENST00000584773.1 ENST00000585096.1 ENST00000258962.4	SRSF1 Links Ensembl NCBI GeneCards UniProt Show fit	serine/arginine-rich splicing factor 1
chr16_+_67596310 Show fit	5.80	ENST00000264010.4 ENST00000401394.1	CTCF Links Ensembl NCBI GeneCards UniProt Show fit	CCCTC-binding factor (zinc finger protein)
chr12_-_6961050 Show fit	5.58	ENST00000538862.2	CDCA3 Links Ensembl NCBI GeneCards UniProt Show fit	cell division cycle associated 3
chr5_-_176433350 Show fit	5.34	ENST00000377227.4 ENST00000377219.2	UIMC1 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin interaction motif containing 1
chr10_-_5060201 Show fit	5.34	ENST00000407674.1	AKR1C2 Links Ensembl NCBI GeneCards UniProt Show fit	aldo-keto reductase family 1, member C2
chr16_+_69458537 Show fit	5.33	ENST00000515314.1 ENST00000561792.1 ENST00000568237.1	CYB5B Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome b5 type B (outer mitochondrial membrane)
chr10_-_5060147 Show fit	5.28	ENST00000604507.1	AKR1C2 Links Ensembl NCBI GeneCards UniProt Show fit	aldo-keto reductase family 1, member C2
chr7_-_76255444 Show fit	5.27	ENST00000454397.1	POMZP3 Links Ensembl NCBI GeneCards UniProt Show fit	POM121 and ZP3 fusion
chr20_-_60942361 Show fit	5.15	ENST00000252999.3	LAMA5 Links Ensembl NCBI GeneCards UniProt Show fit	laminin, alpha 5
chr14_-_45603657 Show fit	4.99	ENST00000396062.3	FKBP3 Links Ensembl NCBI GeneCards UniProt Show fit	FK506 binding protein 3, 25kDa
chr1_+_114472222 Show fit	4.87	ENST00000369558.1 ENST00000369561.4	HIPK1 Links Ensembl NCBI GeneCards UniProt Show fit	homeodomain interacting protein kinase 1
chr1_+_114471809 Show fit	4.87	ENST00000426820.2	HIPK1 Links Ensembl NCBI GeneCards UniProt Show fit	homeodomain interacting protein kinase 1
chr11_-_66112555 Show fit	4.84	ENST00000425825.2 ENST00000359957.3	BRMS1 Links Ensembl NCBI GeneCards UniProt Show fit	breast cancer metastasis suppressor 1
chr10_+_51565188 Show fit	4.79	ENST00000430396.2 ENST00000374087.4 ENST00000414907.2	NCOA4 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor coactivator 4
chr17_-_26662464 Show fit	4.78	ENST00000579419.1 ENST00000585313.1 ENST00000395418.3 ENST00000578985.1 ENST00000577498.1 ENST00000585089.1 ENST00000357896.3	IFT20 Links Ensembl NCBI GeneCards UniProt Show fit	intraflagellar transport 20 homolog (Chlamydomonas)
chrX_+_51636629 Show fit	4.75	ENST00000375722.1 ENST00000326587.7 ENST00000375695.2	MAGED1 Links Ensembl NCBI GeneCards UniProt Show fit	melanoma antigen family D, 1
chr12_+_54378923 Show fit	4.71	ENST00000303460.4	HOXC10 Links Ensembl NCBI GeneCards UniProt Show fit	homeobox C10
chr4_+_26322185 Show fit	4.68	ENST00000361572.6	RBPJ Links Ensembl NCBI GeneCards UniProt Show fit	recombination signal binding protein for immunoglobulin kappa J region
chr17_+_34640031 Show fit	4.66	ENST00000339270.6 ENST00000482104.1	CCL4L2 Links Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-C motif) ligand 4-like 2
chr7_+_134576317 Show fit	4.63	ENST00000424922.1 ENST00000495522.1	CALD1 Links Ensembl NCBI GeneCards UniProt Show fit	caldesmon 1
chr1_+_114472481 Show fit	4.60	ENST00000369555.2	HIPK1 Links Ensembl NCBI GeneCards UniProt Show fit	homeodomain interacting protein kinase 1
chr19_+_11546440 Show fit	4.58	ENST00000589126.1 ENST00000588269.1 ENST00000587509.1 ENST00000592741.1 ENST00000593101.1 ENST00000587327.1	PRKCSH Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase C substrate 80K-H
chr1_-_45452240 Show fit	4.53	ENST00000372183.3 ENST00000372182.4 ENST00000360403.2	EIF2B3 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
chrX_+_100663243 Show fit	4.43	ENST00000316594.5	HNRNPH2 Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein H2 (H')
chr4_+_26322409 Show fit	4.25	ENST00000514807.1 ENST00000348160.4 ENST00000509158.1 ENST00000355476.3	RBPJ Links Ensembl NCBI GeneCards UniProt Show fit	recombination signal binding protein for immunoglobulin kappa J region
chr8_-_99954788 Show fit	4.23	ENST00000523601.1	STK3 Links Ensembl NCBI GeneCards UniProt Show fit	serine/threonine kinase 3
chr19_+_11546093 Show fit	4.22	ENST00000591462.1	PRKCSH Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase C substrate 80K-H
chr17_+_34639793 Show fit	4.18	ENST00000394465.2 ENST00000394463.2 ENST00000378342.4	CCL4L2 Links Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-C motif) ligand 4-like 2
chr8_-_141810634 Show fit	4.15	ENST00000521986.1 ENST00000523539.1 ENST00000538769.1	PTK2 Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine kinase 2
chr17_-_19281203 Show fit	4.07	ENST00000487415.2	B9D1 Links Ensembl NCBI GeneCards UniProt Show fit	B9 protein domain 1
chr3_-_125094093 Show fit	3.93	ENST00000484491.1 ENST00000492394.1 ENST00000471196.1 ENST00000468369.1 ENST00000544464.1 ENST00000485866.1 ENST00000360647.4	ZNF148 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 148
chr17_-_20370847 Show fit	3.91	ENST00000423676.3 ENST00000324290.5	LGALS9B Links Ensembl NCBI GeneCards UniProt Show fit	lectin, galactoside-binding, soluble, 9B
chr22_+_19929130 Show fit	3.90	ENST00000361682.6 ENST00000403184.1 ENST00000403710.1 ENST00000407537.1	COMT Links Ensembl NCBI GeneCards UniProt Show fit	catechol-O-methyltransferase
chr21_-_27107344 Show fit	3.88	ENST00000457143.2	ATP5J Links Ensembl NCBI GeneCards UniProt Show fit	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr21_-_27107198 Show fit	3.79	ENST00000400094.1	ATP5J Links Ensembl NCBI GeneCards UniProt Show fit	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr1_+_89150245 Show fit	3.65	ENST00000370513.5	PKN2 Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase N2
chr5_+_50678921 Show fit	3.65	ENST00000230658.7	ISL1 Links Ensembl NCBI GeneCards UniProt Show fit	ISL LIM homeobox 1
chr21_-_27107283 Show fit	3.55	ENST00000284971.3 ENST00000400099.1	ATP5J Links Ensembl NCBI GeneCards UniProt Show fit	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr1_+_39456895 Show fit	3.47	ENST00000432648.3 ENST00000446189.2 ENST00000372984.4	AKIRIN1 Links Ensembl NCBI GeneCards UniProt Show fit	akirin 1
chr5_+_85913721 Show fit	3.45	ENST00000247655.3 ENST00000509578.1 ENST00000515763.1	COX7C Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome c oxidase subunit VIIc
chr2_+_162087577 Show fit	3.38	ENST00000439442.1	TANK Links Ensembl NCBI GeneCards UniProt Show fit	TRAF family member-associated NFKB activator
chr2_+_120687335 Show fit	3.33	ENST00000544261.1	PTPN4 Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr15_-_83621435 Show fit	3.16	ENST00000450735.2 ENST00000426485.1 ENST00000399166.2 ENST00000304231.8	HOMER2 Links Ensembl NCBI GeneCards UniProt Show fit	homer homolog 2 (Drosophila)
chr5_-_137514333 Show fit	3.10	ENST00000411594.2 ENST00000430331.1	BRD8 Links Ensembl NCBI GeneCards UniProt Show fit	bromodomain containing 8
chrX_+_109245863 Show fit	3.00	ENST00000372072.3	TMEM164 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 164
chr2_+_189839046 Show fit	3.00	ENST00000304636.3 ENST00000317840.5	COL3A1 Links Ensembl NCBI GeneCards UniProt Show fit	collagen, type III, alpha 1
chr7_-_87849340 Show fit	2.98	ENST00000419179.1 ENST00000265729.2	SRI Links Ensembl NCBI GeneCards UniProt Show fit	sorcin
chr1_+_89149905 Show fit	2.87	ENST00000316005.7 ENST00000370521.3 ENST00000370505.3	PKN2 Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase N2
chr4_-_73434498 Show fit	2.83	ENST00000286657.4	ADAMTS3 Links Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr19_-_44174305 Show fit	2.81	ENST00000601723.1 ENST00000339082.3	PLAUR Links Ensembl NCBI GeneCards UniProt Show fit	plasminogen activator, urokinase receptor
chr22_+_35776828 Show fit	2.79	ENST00000216117.8	HMOX1 Links Ensembl NCBI GeneCards UniProt Show fit	heme oxygenase (decycling) 1
chr4_-_140005443 Show fit	2.75	ENST00000510408.1 ENST00000420916.2 ENST00000358635.3	ELF2 Links Ensembl NCBI GeneCards UniProt Show fit	E74-like factor 2 (ets domain transcription factor)
chr12_-_49351303 Show fit	2.73	ENST00000256682.4	ARF3 Links Ensembl NCBI GeneCards UniProt Show fit	ADP-ribosylation factor 3
chr2_+_234601512 Show fit	2.71	ENST00000305139.6	UGT1A6 Links Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase 1 family, polypeptide A6
chr17_-_74497432 Show fit	2.70	ENST00000590288.1 ENST00000313080.4 ENST00000592123.1 ENST00000591255.1 ENST00000585989.1 ENST00000591697.1 ENST00000389760.4	RHBDF2 Links Ensembl NCBI GeneCards UniProt Show fit	rhomboid 5 homolog 2 (Drosophila)
chr22_+_40441456 Show fit	2.69	ENST00000402203.1	TNRC6B Links Ensembl NCBI GeneCards UniProt Show fit	trinucleotide repeat containing 6B
chr6_-_106773291 Show fit	2.50	ENST00000343245.3	ATG5 Links Ensembl NCBI GeneCards UniProt Show fit	autophagy related 5
chr19_+_11546153 Show fit	2.48	ENST00000591946.1 ENST00000252455.2 ENST00000412601.1	PRKCSH Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase C substrate 80K-H
chr6_+_26158343 Show fit	2.45	ENST00000377777.4 ENST00000289316.2	HIST1H2BD Links Ensembl NCBI GeneCards UniProt Show fit	histone cluster 1, H2bd
chr1_-_205290865 Show fit	2.45	ENST00000367157.3	NUAK2 Links Ensembl NCBI GeneCards UniProt Show fit	NUAK family, SNF1-like kinase, 2
chr4_-_151936865 Show fit	2.26	ENST00000535741.1	LRBA Links Ensembl NCBI GeneCards UniProt Show fit	LPS-responsive vesicle trafficking, beach and anchor containing
chr12_-_49351228 Show fit	2.22	ENST00000541959.1 ENST00000447318.2	ARF3 Links Ensembl NCBI GeneCards UniProt Show fit	ADP-ribosylation factor 3
chr17_+_57970469 Show fit	2.16	ENST00000443572.2 ENST00000406116.3 ENST00000225577.4 ENST00000393021.3	RPS6KB1 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr17_+_75084717 Show fit	2.11	ENST00000561721.2 ENST00000589827.1 ENST00000392476.2	SEC14L1 Links Ensembl NCBI GeneCards UniProt Show fit	SEC14-like 1 (S. cerevisiae)
chr1_-_224517823 Show fit	1.78	ENST00000469968.1 ENST00000436927.1 ENST00000469075.1 ENST00000488718.1 ENST00000482491.1 ENST00000340871.4 ENST00000492281.1 ENST00000361463.3 ENST00000391875.2 ENST00000461546.1	NVL Links Ensembl NCBI GeneCards UniProt Show fit	nuclear VCP-like
chr14_+_96722539 Show fit	1.61	ENST00000553356.1	BDKRB1 Links Ensembl NCBI GeneCards UniProt Show fit	bradykinin receptor B1
chr6_-_106773610 Show fit	1.52	ENST00000369076.3 ENST00000369070.1	ATG5 Links Ensembl NCBI GeneCards UniProt Show fit	autophagy related 5
chr1_+_27648709 Show fit	1.45	ENST00000608611.1 ENST00000466759.1 ENST00000464813.1 ENST00000498220.1	TMEM222 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 222
chr3_-_52488048 Show fit	1.43	ENST00000232975.3	TNNC1 Links Ensembl NCBI GeneCards UniProt Show fit	troponin C type 1 (slow)
chr17_+_38296576 Show fit	1.39	ENST00000264645.7	CASC3 Links Ensembl NCBI GeneCards UniProt Show fit	cancer susceptibility candidate 3
chr11_-_64889252 Show fit	1.33	ENST00000525297.1 ENST00000529259.1	FAU Links Ensembl NCBI GeneCards UniProt Show fit	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
chr6_-_26124138 Show fit	1.30	ENST00000314332.5 ENST00000396984.1	HIST1H2BC Links Ensembl NCBI GeneCards UniProt Show fit	histone cluster 1, H2bc
chr14_-_107211459 Show fit	1.28	ENST00000390636.2	IGHV3-73 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-73
chr1_+_27648648 Show fit	1.24	ENST00000374076.4	TMEM222 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 222
chr3_-_52443799 Show fit	1.13	ENST00000470173.1 ENST00000296288.5	BAP1 Links Ensembl NCBI GeneCards UniProt Show fit	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr12_-_90024360 Show fit	1.13	ENST00000393164.2	ATP2B1 Links Ensembl NCBI GeneCards UniProt Show fit	ATPase, Ca++ transporting, plasma membrane 1
chr1_-_153066998 Show fit	1.09	ENST00000368750.3	SPRR2E Links Ensembl NCBI GeneCards UniProt Show fit	small proline-rich protein 2E
chr21_+_19617140 Show fit	1.08	ENST00000299295.2 ENST00000338326.3	CHODL Links Ensembl NCBI GeneCards UniProt Show fit	chondrolectin
chr7_-_38370536 Show fit	1.08	ENST00000390343.2	TRGV8 Links Ensembl NCBI GeneCards UniProt Show fit	T cell receptor gamma variable 8
chr2_-_85895295 Show fit	0.94	ENST00000428225.1 ENST00000519937.2	SFTPB Links Ensembl NCBI GeneCards UniProt Show fit	surfactant protein B
chr22_-_41215291 Show fit	0.93	ENST00000542412.1 ENST00000544408.1	SLC25A17 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr4_-_69817481 Show fit	0.92	ENST00000251566.4	UGT2A3 Links Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase 2 family, polypeptide A3
chr1_-_13052998 Show fit	0.91	ENST00000436041.1	WI2-3308P17.2 Links Ensembl NCBI GeneCards UniProt Show fit	Uncharacterized protein
chr1_-_204135450 Show fit	0.87	ENST00000272190.8 ENST00000367195.2	REN Links Ensembl NCBI GeneCards UniProt Show fit	renin
chr14_-_107114267 Show fit	0.73	ENST00000454421.2	IGHV3-64 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-64
chr11_+_64073699 Show fit	0.66	ENST00000405666.1 ENST00000468670.1	ESRRA Links Ensembl NCBI GeneCards UniProt Show fit	estrogen-related receptor alpha
chr1_-_204165610 Show fit	0.63	ENST00000367194.4	KISS1 Links Ensembl NCBI GeneCards UniProt Show fit	KiSS-1 metastasis-suppressor
chr7_-_81399355 Show fit	0.51	ENST00000457544.2	HGF Links Ensembl NCBI GeneCards UniProt Show fit	hepatocyte growth factor (hepapoietin A; scatter factor)
chr13_+_53602894 Show fit	0.45	ENST00000219022.2	OLFM4 Links Ensembl NCBI GeneCards UniProt Show fit	olfactomedin 4
chr3_+_137728842 Show fit	0.35	ENST00000183605.5	CLDN18 Links Ensembl NCBI GeneCards UniProt Show fit	claudin 18
chr1_+_150980889 Show fit	0.30	ENST00000450884.1 ENST00000271620.3 ENST00000271619.8 ENST00000368937.1 ENST00000431193.1 ENST00000368936.1	PRUNE Links Ensembl NCBI GeneCards UniProt Show fit	prune exopolyphosphatase
chr2_-_208030647 Show fit	0.20	ENST00000309446.6	KLF7 Links Ensembl NCBI GeneCards UniProt Show fit	Kruppel-like factor 7 (ubiquitous)
chr12_-_52867569 Show fit	0.14	ENST00000252250.6	KRT6C Links Ensembl NCBI GeneCards UniProt Show fit	keratin 6C
chr2_-_216003127 Show fit	0.11	ENST00000412081.1 ENST00000272895.7	ABCA12 Links Ensembl NCBI GeneCards UniProt Show fit	ATP-binding cassette, sub-family A (ABC1), member 12
chr10_-_23003460 Show fit	0.10	ENST00000376573.4	PIP4K2A Links Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr6_+_29079668 Show fit	0.08	ENST00000377169.1	OR2J3 Links Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor, family 2, subfamily J, member 3
chr2_-_39664405 Show fit	0.07	ENST00000341681.5 ENST00000263881.3	MAP4K3 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase kinase 3
chr2_-_27341966 Show fit	0.06	ENST00000402394.1 ENST00000402550.1 ENST00000260595.5	CGREF1 Links Ensembl NCBI GeneCards UniProt Show fit	cell growth regulator with EF-hand domain 1
chr2_+_108905325 Show fit	0.01	ENST00000438339.1 ENST00000409880.1 ENST00000437390.2	SULT1C2 Links Ensembl NCBI GeneCards UniProt Show fit	sulfotransferase family, cytosolic, 1C, member 2

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.4	19.2	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
5.1	15.2	GO:0046098	hypoxanthine salvage(GO:0043103) guanine metabolic process(GO:0046098)
4.6	23.0	GO:1904844	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
3.6	47.2	GO:0019388	galactose catabolic process(GO:0019388)
3.2	9.7	GO:0006001	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
3.0	8.9	GO:1905068	arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
2.5	22.4	GO:0060235	lens induction in camera-type eye(GO:0060235)
2.4	9.5	GO:0038195	urokinase plasminogen activator signaling pathway(GO:0038195)
2.2	11.1	GO:1902896	terminal web assembly(GO:1902896)
2.0	18.3	GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
1.9	5.8	GO:0070602	regulation of centromeric sister chromatid cohesion(GO:0070602)
1.7	8.3	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
1.6	16.1	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
1.5	10.6	GO:0009753	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
1.3	4.0	GO:0044034	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
1.2	6.2	GO:0009146	purine nucleoside triphosphate catabolic process(GO:0009146)
1.2	3.6	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
1.0	20.3	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.9	2.8	GO:0006788	heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806)
0.9	5.3	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
0.9	5.3	GO:0035803	egg coat formation(GO:0035803)
0.9	6.1	GO:1902962	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.8	4.2	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.8	10.2	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.8	3.9	GO:0031337	cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.7	2.2	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.7	6.9	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.7	5.9	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.6	6.4	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.6	8.1	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.6	4.7	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.6	1.1	GO:0035522	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.6	4.5	GO:0032057	negative regulation of translational initiation in response to stress(GO:0032057)
0.6	3.4	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.5	6.5	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.5	2.8	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.5	6.1	GO:0051451	myoblast migration(GO:0051451)
0.5	4.1	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.4	11.6	GO:0006337	nucleosome disassembly(GO:0006337)
0.4	4.8	GO:2000210	positive regulation of anoikis(GO:2000210)
0.4	3.0	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.4	40.1	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
0.4	11.3	GO:0006491	N-glycan processing(GO:0006491)
0.4	9.0	GO:0098779	mitophagy in response to mitochondrial depolarization(GO:0098779)
0.4	3.0	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.4	1.4	GO:0032972	diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.4	11.2	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.3	3.3	GO:0048875	chemical homeostasis within a tissue(GO:0048875)
0.2	1.1	GO:1901660	calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
0.2	6.1	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.2	0.9	GO:0002018	renin-angiotensin regulation of aldosterone production(GO:0002018)
0.2	2.1	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.2	2.7	GO:0052696	flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2	13.7	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.2	18.8	GO:0036498	IRE1-mediated unfolded protein response(GO:0036498)
0.2	3.4	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2	2.7	GO:0060211	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.2	6.5	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.2	3.1	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.2	4.8	GO:0006622	protein targeting to lysosome(GO:0006622)
0.1	9.1	GO:0000186	activation of MAPKK activity(GO:0000186)
0.1	0.6	GO:0033686	positive regulation of luteinizing hormone secretion(GO:0033686)
0.1	1.4	GO:0008298	intracellular mRNA localization(GO:0008298)
0.1	5.0	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.1	0.4	GO:2000389	regulation of neutrophil extravasation(GO:2000389)
0.1	3.1	GO:0043968	histone H2A acetylation(GO:0043968)
0.1	5.2	GO:0001755	neural crest cell migration(GO:0001755)
0.1	0.9	GO:0052695	cellular glucuronidation(GO:0052695)
0.1	7.0	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.1	4.8	GO:0048247	lymphocyte chemotaxis(GO:0048247)
0.1	2.8	GO:0050855	regulation of B cell receptor signaling pathway(GO:0050855)
0.1	1.3	GO:0002227	innate immune response in mucosa(GO:0002227)
0.1	3.9	GO:0021762	substantia nigra development(GO:0021762)
0.1	2.5	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	1.6	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0	1.8	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.0	0.3	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
0.0	2.0	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	2.6	GO:0042058	regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0	9.2	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0	0.7	GO:1900078	positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0	1.1	GO:0007517	muscle organ development(GO:0007517)
0.0	0.9	GO:0007585	respiratory gaseous exchange(GO:0007585)
0.0	0.1	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.0	4.1	GO:0043010	camera-type eye development(GO:0043010)
0.0	3.3	GO:0001666	response to hypoxia(GO:0001666)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.4	16.1	GO:1902636	kinociliary basal body(GO:1902636)
2.7	18.8	GO:0005785	signal recognition particle receptor complex(GO:0005785)
1.9	11.1	GO:1990357	terminal web(GO:1990357)
1.8	8.9	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
1.4	20.3	GO:0008290	F-actin capping protein complex(GO:0008290) Flemming body(GO:0090543)
1.4	23.0	GO:0043020	NADPH oxidase complex(GO:0043020)
1.3	5.2	GO:0043260	laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
1.2	14.9	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
1.2	25.2	GO:0005839	proteasome core complex(GO:0005839)
1.1	9.5	GO:0071438	invadopodium membrane(GO:0071438)
1.0	6.1	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.7	6.1	GO:0061574	ASAP complex(GO:0061574)
0.7	4.0	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.6	11.2	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.6	4.5	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.5	10.8	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.5	4.7	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.5	7.6	GO:0005662	DNA replication factor A complex(GO:0005662)
0.5	5.3	GO:0070531	BRCA1-A complex(GO:0070531)
0.4	3.0	GO:0044326	dendritic spine neck(GO:0044326)
0.4	11.3	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.3	7.3	GO:0035145	exon-exon junction complex(GO:0035145)
0.3	4.8	GO:0044754	autolysosome(GO:0044754)
0.3	4.6	GO:0030478	actin cap(GO:0030478)
0.3	4.1	GO:0036038	MKS complex(GO:0036038)
0.3	21.8	GO:0005811	lipid particle(GO:0005811)
0.3	3.0	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2	3.4	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.2	1.4	GO:1990584	cardiac Troponin complex(GO:1990584)
0.2	0.9	GO:0097208	alveolar lamellar body(GO:0097208)
0.2	4.8	GO:0070822	Sin3-type complex(GO:0070822)
0.2	22.1	GO:0005913	cell-cell adherens junction(GO:0005913)
0.1	3.1	GO:0000812	Swr1 complex(GO:0000812)
0.1	19.3	GO:0005938	cell cortex(GO:0005938)
0.1	16.8	GO:0016605	PML body(GO:0016605)
0.1	10.5	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1	6.4	GO:0000118	histone deacetylase complex(GO:0000118)
0.1	6.5	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1	3.2	GO:0032420	stereocilium(GO:0032420)
0.1	3.8	GO:0000786	nucleosome(GO:0000786)
0.1	1.1	GO:0032591	dendritic spine membrane(GO:0032591)
0.1	1.8	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.1	7.5	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	4.1	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	2.0	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.0	2.8	GO:0005901	caveola(GO:0005901)
0.0	1.5	GO:0030315	T-tubule(GO:0030315)
0.0	3.9	GO:0043197	dendritic spine(GO:0043197)
0.0	1.1	GO:0031519	PcG protein complex(GO:0031519)
0.0	5.1	GO:0031965	nuclear membrane(GO:0031965)
0.0	3.6	GO:0000793	condensed chromosome(GO:0000793)
0.0	0.1	GO:0097209	epidermal lamellar body(GO:0097209)
0.0	47.5	GO:0070062	extracellular exosome(GO:0070062)
0.0	0.7	GO:0045171	intercellular bridge(GO:0045171)
0.0	24.3	GO:0005783	endoplasmic reticulum(GO:0005783)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
15.7	47.2	GO:0003978	UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
6.3	18.8	GO:0005047	signal recognition particle binding(GO:0005047)
3.2	16.1	GO:0002046	opsin binding(GO:0002046)
3.2	9.5	GO:0030377	urokinase plasminogen activator receptor activity(GO:0030377)
2.1	6.2	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
1.9	9.7	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
1.8	10.6	GO:0047115	phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
1.2	25.2	GO:0070628	proteasome binding(GO:0070628)
1.2	23.0	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
1.0	5.9	GO:0044547	DNA topoisomerase binding(GO:0044547)
0.9	2.8	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
0.8	8.3	GO:0000150	recombinase activity(GO:0000150)
0.7	2.2	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.7	4.0	GO:0019776	Atg8 ligase activity(GO:0019776)
0.6	6.2	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.6	5.3	GO:0032190	acrosin binding(GO:0032190)
0.6	3.4	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.6	3.9	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
0.5	1.6	GO:0004947	bradykinin receptor activity(GO:0004947)
0.5	6.1	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.5	14.9	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.5	4.1	GO:0008158	hedgehog receptor activity(GO:0008158)
0.5	3.2	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.4	8.3	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.4	9.9	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.4	2.1	GO:0039552	RIG-I binding(GO:0039552)
0.3	1.4	GO:0031013	troponin I binding(GO:0031013)
0.3	9.1	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.3	5.3	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.3	11.6	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.3	6.5	GO:0004697	protein kinase C activity(GO:0004697)
0.2	4.1	GO:0008432	JUN kinase binding(GO:0008432)
0.2	2.9	GO:0017049	GTP-Rho binding(GO:0017049)
0.2	3.3	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2	11.3	GO:0005080	protein kinase C binding(GO:0005080)
0.2	3.0	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.2	3.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.2	4.6	GO:0005523	tropomyosin binding(GO:0005523)
0.2	9.0	GO:0051879	Hsp90 protein binding(GO:0051879)
0.2	5.0	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2	9.2	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
0.1	11.3	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1	31.4	GO:0051015	actin filament binding(GO:0051015)
0.1	4.8	GO:0051059	NF-kappaB binding(GO:0051059)
0.1	10.2	GO:0019003	GDP binding(GO:0019003)
0.1	3.6	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.1	3.4	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	4.8	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.1	11.2	GO:0015078	hydrogen ion transmembrane transporter activity(GO:0015078)
0.1	4.2	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.1	3.6	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.1	3.0	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1	4.8	GO:0050681	androgen receptor binding(GO:0050681)
0.1	1.0	GO:0030280	structural constituent of epidermis(GO:0030280)
0.1	12.4	GO:0005516	calmodulin binding(GO:0005516)
0.1	8.1	GO:0003697	single-stranded DNA binding(GO:0003697)
0.1	10.4	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1	4.5	GO:0003743	translation initiation factor activity(GO:0003743)
0.1	29.4	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
0.0	2.0	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	0.9	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	1.1	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.1	GO:0034191	lipid-transporting ATPase activity(GO:0034040) apolipoprotein A-I receptor binding(GO:0034191)
0.0	2.7	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	1.1	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0	0.6	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.0	6.5	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	3.9	GO:0030246	carbohydrate binding(GO:0030246)
0.0	7.6	GO:0003712	transcription cofactor activity(GO:0003712)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	9.5	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.3	23.0	PID RAC1 PATHWAY	RAC1 signaling pathway
0.2	5.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.2	5.0	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2	8.9	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.1	12.5	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.1	4.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.1	13.6	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.1	9.0	PID ILK PATHWAY	Integrin-linked kinase signaling
0.1	5.3	PID ATM PATHWAY	ATM pathway
0.1	6.1	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.1	4.9	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.1	3.0	NABA COLLAGENS	Genes encoding collagen proteins
0.1	4.7	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.1	1.9	PID RHOA PATHWAY	RhoA signaling pathway
0.0	4.8	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	2.8	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	4.9	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	5.3	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	5.5	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	1.1	PID CMYB PATHWAY	C-MYB transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	9.7	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.7	8.9	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.7	11.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.6	15.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.6	63.1	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.5	8.3	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.5	11.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.3	4.7	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.3	9.5	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.3	9.0	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.3	18.8	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2	2.7	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.2	5.0	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.2	16.3	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.2	9.3	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.2	3.6	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2	4.1	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.2	4.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	47.2	REACTOME METABOLISM OF CARBOHYDRATES	Genes involved in Metabolism of carbohydrates
0.1	2.8	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	2.7	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	6.1	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	4.0	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1	2.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	5.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	3.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.1	4.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	3.8	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.1	1.4	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	4.4	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	3.4	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	1.4	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	2.1	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	5.9	REACTOME TRANSLATION	Genes involved in Translation