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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TBP

Z-value: 2.60

Motif logo

Transcription factors associated with TBP

Gene Symbol Gene ID Gene Info
ENSG00000112592.8 TATA-box binding protein

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBPhg19_v2_chr6_+_170863421_170863484-0.351.2e-07Click!

Activity profile of TBP motif

Sorted Z-values of TBP motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_91539918 52.38 ENST00000548218.1
decorin
chr11_-_5248294 49.81 ENST00000335295.4
hemoglobin, beta
chr19_-_6720686 48.86 ENST00000245907.6
complement component 3
chr16_+_56685796 47.72 ENST00000334346.2
ENST00000562399.1
metallothionein 1B
chr5_-_42812143 47.32 ENST00000514985.1
selenoprotein P, plasma, 1
chr1_-_59043166 45.27 ENST00000371225.2
tumor-associated calcium signal transducer 2
chr5_-_42811986 43.18 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chr20_-_43883197 35.66 ENST00000338380.2
secretory leukocyte peptidase inhibitor
chr12_-_15038779 34.93 ENST00000228938.5
ENST00000539261.1
matrix Gla protein
chr16_+_56659687 34.62 ENST00000568293.1
ENST00000330439.6
metallothionein 1E
chr1_+_153330322 32.69 ENST00000368738.3
S100 calcium binding protein A9
chr11_-_5276008 30.48 ENST00000336906.4
hemoglobin, gamma G
chr9_+_130911770 29.86 ENST00000372998.1
lipocalin 2
chr21_-_28217721 29.46 ENST00000284984.3
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr7_+_75931861 28.74 ENST00000248553.6
heat shock 27kDa protein 1
chr9_+_130911723 27.76 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
lipocalin 2
chr1_-_153363452 26.52 ENST00000368732.1
ENST00000368733.3
S100 calcium binding protein A8
chr6_+_31783291 25.91 ENST00000375651.5
ENST00000608703.1
ENST00000458062.2
heat shock 70kDa protein 1A
chr3_+_127634312 25.37 ENST00000407609.3
kelch repeat and BTB (POZ) domain containing 12
chr1_+_86046433 24.81 ENST00000451137.2
cysteine-rich, angiogenic inducer, 61
chr17_+_56315936 24.42 ENST00000543544.1
lactoperoxidase
chr10_-_90712520 24.39 ENST00000224784.6
actin, alpha 2, smooth muscle, aorta
chr11_-_5255696 23.63 ENST00000292901.3
ENST00000417377.1
hemoglobin, delta
chr16_+_56703737 22.93 ENST00000569155.1
metallothionein 1H
chr11_-_2160611 22.32 ENST00000416167.2
insulin-like growth factor 2 (somatomedin A)
chr11_-_5271122 22.20 ENST00000330597.3
hemoglobin, gamma A
chr11_-_2160180 21.55 ENST00000381406.4
insulin-like growth factor 2 (somatomedin A)
chr12_-_11463353 21.14 ENST00000279575.1
ENST00000535904.1
ENST00000445719.2
proline-rich protein BstNI subfamily 4
chr17_-_61996136 20.86 ENST00000342364.4
growth hormone 1
chr19_-_33793430 20.69 ENST00000498907.2
CCAAT/enhancer binding protein (C/EBP), alpha
chr1_+_159557607 20.59 ENST00000255040.2
amyloid P component, serum
chr1_-_182360918 20.33 ENST00000339526.4
glutamate-ammonia ligase
chr19_-_36247910 19.44 ENST00000587965.1
ENST00000004982.3
heat shock protein, alpha-crystallin-related, B6
chr6_-_33239712 19.39 ENST00000436044.2
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr7_+_142829162 19.34 ENST00000291009.3
prolactin-induced protein
chr1_-_182360498 19.15 ENST00000417584.2
glutamate-ammonia ligase
chr12_-_53012343 19.03 ENST00000305748.3
keratin 73
chr16_+_56703703 19.01 ENST00000332374.4
metallothionein 1H
chr12_-_11508520 18.71 ENST00000545626.1
ENST00000500254.2
proline-rich protein BstNI subfamily 1
chr17_-_48278983 18.54 ENST00000225964.5
collagen, type I, alpha 1
chr5_+_40909354 17.64 ENST00000313164.9
complement component 7
chr9_+_117092149 17.51 ENST00000431067.2
ENST00000412657.1
orosomucoid 2
chr1_-_182361327 17.46 ENST00000331872.6
ENST00000311223.5
glutamate-ammonia ligase
chr11_-_5255861 17.35 ENST00000380299.3
hemoglobin, delta
chr17_-_61996160 17.20 ENST00000458650.2
ENST00000351388.4
ENST00000323322.5
growth hormone 1
chr20_+_30193083 16.97 ENST00000376112.3
ENST00000376105.3
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
chr1_-_153044083 16.87 ENST00000341611.2
small proline-rich protein 2B
chr17_-_39780819 16.85 ENST00000311208.8
keratin 17
chr3_+_122044084 16.70 ENST00000264474.3
ENST00000479204.1
cystatin A (stefin A)
chr8_-_6735451 16.68 ENST00000297439.3
defensin, beta 1
chr6_-_52860171 16.49 ENST00000370963.4
glutathione S-transferase alpha 4
chr20_+_31823792 16.43 ENST00000375413.4
ENST00000354297.4
ENST00000375422.2
BPI fold containing family A, member 1
chr12_+_124155652 16.42 ENST00000426174.2
ENST00000303372.5
tectonic family member 2
chr6_-_52859968 16.41 ENST00000370959.1
glutathione S-transferase alpha 4
chr9_+_124088860 16.36 ENST00000373806.1
gelsolin
chr1_-_153013588 16.36 ENST00000360379.3
small proline-rich protein 2D
chr21_-_43735446 16.23 ENST00000398431.2
trefoil factor 3 (intestinal)
chr1_+_89829610 16.11 ENST00000370456.4
ENST00000535065.1
guanylate binding protein family, member 6
chr7_-_100026280 16.03 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
zinc finger, CW type with PWWP domain 1
chr12_-_52867569 15.83 ENST00000252250.6
keratin 6C
chr9_-_33447584 15.80 ENST00000297991.4
aquaporin 3 (Gill blood group)
chr1_-_95007193 15.68 ENST00000370207.4
ENST00000334047.7
coagulation factor III (thromboplastin, tissue factor)
chr2_-_21266935 15.60 ENST00000233242.1
apolipoprotein B
chr6_+_43543942 15.56 ENST00000372226.1
ENST00000443535.1
polymerase (DNA directed), eta
chr17_-_48546324 15.56 ENST00000508540.1
chondroadherin
chr21_-_43735628 15.55 ENST00000291525.10
ENST00000518498.1
trefoil factor 3 (intestinal)
chr17_-_39661849 15.18 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
keratin 13
chr6_+_27100811 14.76 ENST00000359193.2
histone cluster 1, H2ag
chr3_+_193853927 14.71 ENST00000232424.3
hes family bHLH transcription factor 1
chr16_-_56701933 14.62 ENST00000568675.1
ENST00000569500.1
ENST00000444837.2
ENST00000379811.3
metallothionein 1G
chr3_+_101546827 14.51 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr14_+_75745477 14.27 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FBJ murine osteosarcoma viral oncogene homolog
chr17_+_56315787 14.09 ENST00000262290.4
ENST00000421678.2
lactoperoxidase
chr6_+_26124373 13.95 ENST00000377791.2
ENST00000602637.1
histone cluster 1, H2ac
chr19_+_10381769 13.90 ENST00000423829.2
ENST00000588645.1
intercellular adhesion molecule 1
chr16_+_202686 13.87 ENST00000252951.2
hemoglobin, zeta
chr13_+_53602894 13.86 ENST00000219022.2
olfactomedin 4
chr11_-_18270182 13.51 ENST00000528349.1
ENST00000526900.1
ENST00000529528.1
ENST00000414546.2
ENST00000256733.4
serum amyloid A2
chr2_-_89292422 13.44 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr16_+_56691606 13.03 ENST00000334350.6
metallothionein 1F
chr17_-_61996192 12.99 ENST00000392824.4
chorionic somatomammotropin hormone-like 1
chr9_+_92219919 12.99 ENST00000252506.6
ENST00000375769.1
growth arrest and DNA-damage-inducible, gamma
chr10_+_7745303 12.92 ENST00000429820.1
ENST00000379587.4
inter-alpha-trypsin inhibitor heavy chain 2
chr11_-_2906979 12.77 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr17_-_74707037 12.73 ENST00000355797.3
ENST00000375036.2
ENST00000449428.2
matrix-remodelling associated 7
chr3_+_148545586 12.71 ENST00000282957.4
ENST00000468341.1
carboxypeptidase B1 (tissue)
chr17_-_61951090 12.70 ENST00000345366.7
ENST00000392886.2
ENST00000336844.5
ENST00000560142.1
chorionic somatomammotropin hormone 2
chr12_+_6309517 12.51 ENST00000382519.4
ENST00000009180.4
CD9 molecule
chr12_+_50355647 12.48 ENST00000293599.6
aquaporin 5
chr4_+_74735102 12.47 ENST00000395761.3
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr17_-_39674668 12.46 ENST00000393981.3
keratin 15
chr19_-_45826125 12.37 ENST00000221476.3
creatine kinase, muscle
chr22_+_39916558 12.24 ENST00000337304.2
ENST00000396680.1
activating transcription factor 4
chr7_+_116593292 12.24 ENST00000393446.2
ENST00000265437.5
ENST00000393451.3
suppression of tumorigenicity 7
chr1_+_244998602 12.19 ENST00000411948.2
COX20 cytochrome C oxidase assembly factor
chr1_-_230850043 12.15 ENST00000366667.4
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr9_-_104198042 12.05 ENST00000374855.4
aldolase B, fructose-bisphosphate
chr17_-_48546232 11.97 ENST00000258969.4
chondroadherin
chr6_-_27100529 11.82 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
histone cluster 1, H2bj
chr6_-_27860956 11.79 ENST00000359611.2
histone cluster 1, H2am
chr11_+_18287801 11.77 ENST00000532858.1
ENST00000405158.2
serum amyloid A1
chr18_+_21719018 11.76 ENST00000585037.1
ENST00000415309.2
ENST00000399481.2
ENST00000577705.1
ENST00000327201.6
calcium binding tyrosine-(Y)-phosphorylation regulated
chrX_+_84499081 11.50 ENST00000276123.3
zinc finger protein 711
chr16_+_56691911 11.39 ENST00000568475.1
metallothionein 1F
chr10_+_7745232 11.28 ENST00000358415.4
inter-alpha-trypsin inhibitor heavy chain 2
chr3_+_149192475 11.28 ENST00000465758.1
transmembrane 4 L six family member 4
chr5_+_78407602 11.26 ENST00000274353.5
ENST00000524080.1
betaine--homocysteine S-methyltransferase
chr11_+_18287721 11.18 ENST00000356524.4
serum amyloid A1
chr19_-_10946949 11.09 ENST00000214869.2
ENST00000591695.1
transmembrane emp24 protein transport domain containing 1
chr18_+_21718924 11.07 ENST00000399496.3
calcium binding tyrosine-(Y)-phosphorylation regulated
chr1_+_152635854 11.00 ENST00000368784.1
late cornified envelope 2D
chr15_-_63674034 10.94 ENST00000344366.3
ENST00000422263.2
carbonic anhydrase XII
chrX_+_84499038 10.88 ENST00000373165.3
zinc finger protein 711
chr12_-_11036844 10.87 ENST00000428168.2
proline-rich protein HaeIII subfamily 1
chr17_-_61973929 10.79 ENST00000329882.8
ENST00000453363.3
ENST00000316193.8
chorionic somatomammotropin hormone 1 (placental lactogen)
chr17_-_61988556 10.77 ENST00000309894.5
ENST00000438387.2
ENST00000346606.6
ENST00000561003.1
ENST00000450719.3
ENST00000259003.10
chorionic somatomammotropin hormone-like 1
chr12_+_58013693 10.74 ENST00000320442.4
ENST00000379218.2
solute carrier family 26, member 10
chr20_-_39317868 10.68 ENST00000373313.2
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr12_+_130646999 10.63 ENST00000539839.1
ENST00000229030.4
frizzled family receptor 10
chr10_-_81320151 10.60 ENST00000372325.2
ENST00000372327.5
ENST00000417041.1
surfactant protein A2
chr11_+_1718425 10.59 ENST00000382160.1
keratin associated protein 5-6
chr6_+_27114861 10.55 ENST00000377459.1
histone cluster 1, H2ah
chr16_+_82068830 10.41 ENST00000199936.4
hydroxysteroid (17-beta) dehydrogenase 2
chr1_-_161193349 10.40 ENST00000469730.2
ENST00000463273.1
ENST00000464492.1
ENST00000367990.3
ENST00000470459.2
ENST00000468465.1
ENST00000463812.1
apolipoprotein A-II
chr7_+_72742178 10.30 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FK506 binding protein 6, 36kDa
chr1_+_152881014 10.28 ENST00000368764.3
ENST00000392667.2
involucrin
chr17_+_32646055 10.26 ENST00000394620.1
chemokine (C-C motif) ligand 8
chr5_-_141338627 10.23 ENST00000231484.3
protocadherin 12
chr6_+_33239787 10.16 ENST00000439602.2
ENST00000474973.1
ribosomal protein S18
chr12_-_120765565 10.08 ENST00000423423.3
ENST00000308366.4
phospholipase A2, group IB (pancreas)
chr17_-_61959202 10.08 ENST00000449787.2
ENST00000456543.2
ENST00000423893.2
ENST00000332800.7
growth hormone 2
chr10_+_124320156 9.97 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
deleted in malignant brain tumors 1
chr2_-_163008903 9.85 ENST00000418842.2
ENST00000375497.3
glucagon
chr1_-_216978709 9.84 ENST00000360012.3
estrogen-related receptor gamma
chr12_-_11548496 9.83 ENST00000389362.4
ENST00000565533.1
ENST00000546254.1
proline-rich protein BstNI subfamily 2
proline-rich protein BstNI subfamily 1
chr11_-_116708302 9.76 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
apolipoprotein A-I
chr1_+_207226574 9.72 ENST00000367080.3
ENST00000367079.2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr1_+_206223941 9.70 ENST00000367126.4
arginine vasopressin receptor 1B
chr6_-_26043885 9.66 ENST00000357905.2
histone cluster 1, H2bb
chr16_+_67840986 9.55 ENST00000561639.1
ENST00000567852.1
ENST00000565148.1
ENST00000388833.3
ENST00000561654.1
ENST00000431934.2
translin-associated factor X interacting protein 1
chr12_-_53614155 9.37 ENST00000543726.1
retinoic acid receptor, gamma
chr10_+_124320195 9.37 ENST00000359586.6
deleted in malignant brain tumors 1
chr3_-_194090460 9.23 ENST00000428839.1
ENST00000347624.3
leucine rich repeat containing 15
chr16_-_15950868 9.12 ENST00000396324.3
ENST00000452625.2
ENST00000576790.2
ENST00000300036.5
myosin, heavy chain 11, smooth muscle
chr10_+_17271266 9.06 ENST00000224237.5
vimentin
chr6_+_27806319 9.01 ENST00000606613.1
ENST00000396980.3
histone cluster 1, H2bn
chr19_+_54705025 9.01 ENST00000441429.1
ribosomal protein S9
chr21_-_43786634 9.01 ENST00000291527.2
trefoil factor 1
chrX_+_153626571 8.91 ENST00000424325.2
ribosomal protein L10
chr1_-_153538011 8.89 ENST00000368707.4
S100 calcium binding protein A2
chr10_+_54074033 8.87 ENST00000373970.3
dickkopf WNT signaling pathway inhibitor 1
chr12_-_53614043 8.85 ENST00000338561.5
retinoic acid receptor, gamma
chr4_+_74718906 8.80 ENST00000226524.3
platelet factor 4 variant 1
chr19_+_54704718 8.76 ENST00000391752.1
ENST00000402367.1
ENST00000391751.3
ribosomal protein S9
chr6_+_64282447 8.65 ENST00000370650.2
ENST00000578299.1
protein tyrosine phosphatase type IVA, member 1
chr19_-_5340730 8.47 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
protein tyrosine phosphatase, receptor type, S
chr20_+_36932521 8.43 ENST00000262865.4
bactericidal/permeability-increasing protein
chr16_+_75256507 8.43 ENST00000495583.1
chymotrypsinogen B1
chr14_+_93389425 8.35 ENST00000216492.5
ENST00000334654.4
chromogranin A (parathyroid secretory protein 1)
chr7_+_72742162 8.22 ENST00000431982.2
FK506 binding protein 6, 36kDa
chr1_+_37940153 8.20 ENST00000373087.6
zinc finger CCCH-type containing 12A
chr1_-_203155868 8.16 ENST00000255409.3
chitinase 3-like 1 (cartilage glycoprotein-39)
chr7_+_108210012 8.13 ENST00000249356.3
DnaJ (Hsp40) homolog, subfamily B, member 9
chr1_-_207226313 8.11 ENST00000367084.1
YOD1 deubiquitinase
chr11_-_2182388 8.10 ENST00000421783.1
ENST00000397262.1
ENST00000250971.3
ENST00000381330.4
ENST00000397270.1
insulin
INS-IGF2 readthrough
chr12_+_11081828 8.08 ENST00000381847.3
ENST00000396400.3
proline-rich protein HaeIII subfamily 2
chr1_-_11907829 8.07 ENST00000376480.3
natriuretic peptide A
chr5_+_66254698 8.02 ENST00000405643.1
ENST00000407621.1
ENST00000432426.1
microtubule associated serine/threonine kinase family member 4
chr9_+_135937365 8.02 ENST00000372080.4
ENST00000351304.7
carboxyl ester lipase
chr19_+_2476116 7.98 ENST00000215631.4
ENST00000587345.1
growth arrest and DNA-damage-inducible, beta
chr18_+_56887381 7.95 ENST00000256857.2
ENST00000529320.2
ENST00000420468.2
gastrin-releasing peptide
chr10_+_5135981 7.94 ENST00000380554.3
aldo-keto reductase family 1, member C3
chrX_+_153626708 7.91 ENST00000436473.1
ENST00000344746.4
ENST00000458500.1
ribosomal protein L10
chr12_-_52845910 7.91 ENST00000252252.3
keratin 6B
chr2_-_85895295 7.83 ENST00000428225.1
ENST00000519937.2
surfactant protein B
chr8_-_133097902 7.79 ENST00000262283.5
Otoconin-90
chr2_-_208989225 7.78 ENST00000264376.4
crystallin, gamma D
chr6_-_26216872 7.75 ENST00000244601.3
histone cluster 1, H2bg
chr19_+_54704990 7.72 ENST00000391753.2
ribosomal protein S9
chr6_-_26247259 7.70 ENST00000244537.4
histone cluster 1, H4g
chrX_+_84498989 7.66 ENST00000395402.1
zinc finger protein 711
chr2_-_190044480 7.61 ENST00000374866.3
collagen, type V, alpha 2
chr10_+_22634384 7.58 ENST00000376624.3
ENST00000376603.2
ENST00000376601.1
ENST00000538630.1
ENST00000456231.2
ENST00000313311.6
ENST00000435326.1
sperm associated antigen 6
chr9_-_34691201 7.54 ENST00000378800.3
ENST00000311925.2
chemokine (C-C motif) ligand 19
chr11_+_71238313 7.52 ENST00000398536.4
keratin associated protein 5-7
chr10_+_118305435 7.51 ENST00000369221.2
pancreatic lipase
chr17_+_32683456 7.47 ENST00000225844.2
chemokine (C-C motif) ligand 13
chr6_-_33239612 7.47 ENST00000482399.1
ENST00000445902.2
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr6_+_26156551 7.40 ENST00000304218.3
histone cluster 1, H1e
chr1_-_23886285 7.37 ENST00000374561.5
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chrX_-_7895755 7.17 ENST00000444736.1
ENST00000537427.1
ENST00000442940.1
patatin-like phospholipase domain containing 4
chr17_+_16284104 7.14 ENST00000577958.1
ENST00000302182.3
ENST00000577640.1
ubiquitin B
chr1_+_153003671 7.10 ENST00000307098.4
small proline-rich protein 1B
chrX_+_21874105 7.08 ENST00000429584.2
YY2 transcription factor
chr2_-_79315112 7.08 ENST00000305089.3
regenerating islet-derived 1 beta
chr1_+_149822620 7.01 ENST00000369159.2
histone cluster 2, H2aa4
chr9_-_21077939 6.97 ENST00000380232.2
interferon, beta 1, fibroblast
chr19_+_35773242 6.96 ENST00000222304.3
hepcidin antimicrobial peptide
chr4_+_74606223 6.96 ENST00000307407.3
ENST00000401931.1
interleukin 8
chr6_-_27840099 6.90 ENST00000328488.2
histone cluster 1, H3i

Network of associatons between targets according to the STRING database.

First level regulatory network of TBP

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
16.3 48.9 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
14.2 56.9 GO:0006542 glutamine biosynthetic process(GO:0006542)
12.5 49.8 GO:0030185 nitric oxide transport(GO:0030185)
11.5 57.6 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
9.0 26.9 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
8.9 8.9 GO:0003129 heart induction(GO:0003129)
8.5 59.2 GO:0032119 sequestering of zinc ion(GO:0032119)
7.7 107.5 GO:0015671 oxygen transport(GO:0015671)
7.5 45.3 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
7.4 14.7 GO:0045168 cell-cell signaling involved in cell fate commitment(GO:0045168)
7.2 28.7 GO:0099640 axo-dendritic protein transport(GO:0099640)
6.9 27.5 GO:1900154 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
6.6 52.6 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
6.5 25.9 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
5.8 163.3 GO:0071294 cellular response to zinc ion(GO:0071294)
5.7 17.0 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
5.6 16.7 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
5.4 32.2 GO:0045903 positive regulation of translational fidelity(GO:0045903)
5.3 15.8 GO:0070295 renal water absorption(GO:0070295)
5.2 15.7 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
5.0 20.2 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
4.9 19.7 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
4.9 24.4 GO:0090131 mesenchyme migration(GO:0090131)
4.9 43.9 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
4.8 4.8 GO:0086073 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
4.4 52.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
4.2 12.5 GO:0015670 carbon dioxide transport(GO:0015670)
4.1 24.8 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
4.1 20.6 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
4.1 16.4 GO:0044010 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
4.1 12.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
4.0 12.0 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
3.8 11.3 GO:1903413 cellular response to bile acid(GO:1903413)
3.7 18.5 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072) cellular response to vitamin E(GO:0071306) response to fluoride(GO:1902617)
3.6 18.2 GO:0003431 growth plate cartilage chondrocyte growth(GO:0003430) growth plate cartilage chondrocyte development(GO:0003431) Harderian gland development(GO:0070384)
3.6 10.7 GO:0021571 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
3.5 13.9 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
3.4 10.3 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
3.3 9.8 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
3.3 16.4 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
3.3 16.3 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
3.2 9.7 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
3.0 9.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
3.0 9.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
2.9 17.7 GO:0055064 chloride ion homeostasis(GO:0055064)
2.7 8.2 GO:1990869 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294) negative regulation by host of viral process(GO:0044793) negative regulation by host of viral genome replication(GO:0044828) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
2.7 8.1 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
2.7 8.1 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
2.6 7.9 GO:0016095 polyprenol catabolic process(GO:0016095)
2.6 15.6 GO:0034371 chylomicron remodeling(GO:0034371)
2.5 7.6 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
2.5 7.5 GO:2000547 dendritic cell dendrite assembly(GO:0097026) regulation of dendritic cell dendrite assembly(GO:2000547)
2.5 15.0 GO:0042713 sperm ejaculation(GO:0042713)
2.4 65.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
2.3 11.7 GO:0060356 leucine import(GO:0060356)
2.3 18.5 GO:0034587 piRNA metabolic process(GO:0034587)
2.2 15.6 GO:0071494 cellular response to UV-C(GO:0071494)
2.2 17.5 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
2.2 6.5 GO:0070837 dehydroascorbic acid transport(GO:0070837)
2.1 6.4 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
2.0 8.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
2.0 13.9 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
2.0 29.5 GO:0001542 ovulation from ovarian follicle(GO:0001542)
1.9 19.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
1.9 20.7 GO:0000050 urea cycle(GO:0000050)
1.9 11.3 GO:0050666 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
1.9 5.6 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
1.9 7.5 GO:0002434 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) response to high density lipoprotein particle(GO:0055099) T cell extravasation(GO:0072683) regulation of immune complex clearance by monocytes and macrophages(GO:0090264)
1.9 3.7 GO:0051795 positive regulation of catagen(GO:0051795)
1.9 61.2 GO:0019731 antibacterial humoral response(GO:0019731)
1.8 12.8 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
1.8 14.3 GO:0001661 conditioned taste aversion(GO:0001661)
1.8 5.3 GO:1904437 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
1.8 5.3 GO:0051039 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
1.7 7.0 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
1.7 5.2 GO:0003218 cardiac left ventricle formation(GO:0003218)
1.7 5.1 GO:0001694 histamine biosynthetic process(GO:0001694)
1.7 3.3 GO:0035106 operant conditioning(GO:0035106)
1.6 6.6 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
1.6 6.5 GO:0014807 regulation of somitogenesis(GO:0014807)
1.6 9.7 GO:1903301 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
1.6 9.6 GO:0060613 fat pad development(GO:0060613)
1.6 74.1 GO:0018149 peptide cross-linking(GO:0018149)
1.5 10.6 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
1.5 4.6 GO:0034308 primary alcohol metabolic process(GO:0034308)
1.5 4.6 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
1.5 9.1 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
1.5 5.9 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
1.4 5.7 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
1.4 5.7 GO:0035962 response to interleukin-13(GO:0035962)
1.4 16.9 GO:0051798 positive regulation of hair follicle development(GO:0051798)
1.4 34.9 GO:0001502 cartilage condensation(GO:0001502)
1.4 2.8 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
1.4 31.4 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
1.3 6.6 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
1.3 11.8 GO:0043587 tongue morphogenesis(GO:0043587)
1.3 10.5 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
1.3 5.2 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
1.3 8.9 GO:0019532 oxalate transport(GO:0019532)
1.3 22.8 GO:0003351 epithelial cilium movement(GO:0003351)
1.3 3.8 GO:0035993 subthalamic nucleus development(GO:0021763) deltoid tuberosity development(GO:0035993) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578) cell proliferation involved in outflow tract morphogenesis(GO:0061325)
1.2 18.7 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
1.2 12.4 GO:0006600 creatine metabolic process(GO:0006600)
1.2 4.9 GO:0002215 defense response to nematode(GO:0002215)
1.2 4.8 GO:1905232 cellular response to L-glutamate(GO:1905232)
1.2 7.2 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
1.2 4.7 GO:0042483 negative regulation of odontogenesis(GO:0042483)
1.2 10.5 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
1.2 9.2 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
1.1 4.6 GO:0035425 autocrine signaling(GO:0035425)
1.1 4.4 GO:0019627 urea metabolic process(GO:0019627)
1.0 4.1 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
1.0 21.0 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
1.0 32.9 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
1.0 1.9 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
0.9 20.9 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.9 4.7 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.9 5.6 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.9 7.5 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.9 12.2 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.9 20.2 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.9 9.1 GO:0009414 response to water deprivation(GO:0009414)
0.9 76.8 GO:0070268 cornification(GO:0070268)
0.9 8.7 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.8 8.4 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.8 4.8 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.8 23.0 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.7 8.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.7 5.2 GO:0032097 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.7 10.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.7 2.8 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.7 5.3 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.6 4.5 GO:0070294 renal sodium ion absorption(GO:0070294)
0.6 2.6 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.6 5.0 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.6 17.9 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.6 2.4 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.6 5.8 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.6 12.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.6 1.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.5 10.4 GO:0031424 keratinization(GO:0031424)
0.5 5.8 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.5 6.6 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.5 19.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.5 2.5 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.5 5.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.5 6.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.5 5.4 GO:0030728 ovulation(GO:0030728)
0.4 3.4 GO:0030007 cellular potassium ion homeostasis(GO:0030007)
0.4 2.5 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.4 33.9 GO:0006342 chromatin silencing(GO:0006342)
0.4 2.6 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.4 4.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.4 2.9 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.4 1.8 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.4 12.9 GO:0019433 triglyceride catabolic process(GO:0019433)
0.3 6.8 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.3 1.0 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.3 19.5 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.3 2.0 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.3 0.7 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.3 8.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.3 8.2 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.3 1.8 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.3 1.4 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.3 6.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.3 8.7 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.3 7.1 GO:0034694 response to prostaglandin(GO:0034694)
0.3 1.0 GO:0035356 cellular triglyceride homeostasis(GO:0035356) negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.3 7.8 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.3 2.0 GO:0033327 Leydig cell differentiation(GO:0033327)
0.3 4.6 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.2 28.1 GO:0007586 digestion(GO:0007586)
0.2 10.2 GO:0008038 neuron recognition(GO:0008038)
0.2 11.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.2 10.4 GO:0006953 acute-phase response(GO:0006953)
0.2 4.0 GO:0003334 keratinocyte development(GO:0003334)
0.2 6.0 GO:0060325 face morphogenesis(GO:0060325)
0.2 0.6 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.2 4.8 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.2 1.9 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 11.7 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.2 2.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.2 5.3 GO:0006875 cellular metal ion homeostasis(GO:0006875)
0.2 2.9 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 4.2 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.2 1.0 GO:0040031 snRNA modification(GO:0040031)
0.2 4.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 5.1 GO:0042269 regulation of natural killer cell mediated cytotoxicity(GO:0042269)
0.2 1.4 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2 3.9 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 2.3 GO:0008210 estrogen metabolic process(GO:0008210)
0.1 1.2 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.1 3.6 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 0.9 GO:0072602 interleukin-4 secretion(GO:0072602)
0.1 4.2 GO:0019730 antimicrobial humoral response(GO:0019730)
0.1 3.7 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 0.7 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.1 16.4 GO:0007224 smoothened signaling pathway(GO:0007224)
0.1 3.3 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 4.1 GO:0007140 male meiosis(GO:0007140)
0.1 5.0 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.1 4.6 GO:0015701 bicarbonate transport(GO:0015701)
0.1 1.0 GO:0072678 T cell migration(GO:0072678)
0.1 3.4 GO:0010039 response to iron ion(GO:0010039)
0.1 3.0 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 13.5 GO:0002377 immunoglobulin production(GO:0002377)
0.1 8.3 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.1 3.4 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.1 2.4 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 8.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.9 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 1.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 3.2 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 6.6 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 1.3 GO:0036258 multivesicular body assembly(GO:0036258)
0.0 4.6 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 1.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.3 GO:0002003 angiotensin maturation(GO:0002003)
0.0 2.2 GO:0034620 cellular response to unfolded protein(GO:0034620)
0.0 1.7 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 3.9 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 1.3 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 2.1 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.6 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 2.7 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 3.5 GO:0043542 endothelial cell migration(GO:0043542)
0.0 6.1 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 1.1 GO:0019233 sensory perception of pain(GO:0019233)
0.0 2.6 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.6 GO:0015813 acidic amino acid transport(GO:0015800) L-glutamate transport(GO:0015813)
0.0 0.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 2.0 GO:0034332 adherens junction organization(GO:0034332)
0.0 1.7 GO:0050906 detection of stimulus involved in sensory perception(GO:0050906)
0.0 0.7 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.4 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.1 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 1.5 GO:0006414 translational elongation(GO:0006414)
0.0 3.0 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
12.7 38.1 GO:0070195 growth hormone receptor complex(GO:0070195)
12.5 49.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
9.0 107.5 GO:0005833 hemoglobin complex(GO:0005833)
6.7 26.9 GO:1990745 EARP complex(GO:1990745)
6.1 24.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
3.7 52.4 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
3.3 9.8 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
2.7 52.2 GO:0097386 glial cell projection(GO:0097386)
2.6 15.6 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
2.5 7.6 GO:0005588 collagen type V trimer(GO:0005588)
2.1 22.8 GO:0035686 sperm fibrous sheath(GO:0035686)
2.1 18.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
2.0 12.2 GO:1990037 Lewy body core(GO:1990037)
2.0 112.3 GO:0000786 nucleosome(GO:0000786)
2.0 17.6 GO:0005579 membrane attack complex(GO:0005579)
1.8 82.7 GO:0045095 keratin filament(GO:0045095)
1.8 14.3 GO:0035976 AP1 complex(GO:0035976)
1.6 151.7 GO:0035580 specific granule lumen(GO:0035580)
1.6 27.5 GO:0071682 endocytic vesicle lumen(GO:0071682)
1.5 10.7 GO:0072687 meiotic spindle(GO:0072687)
1.5 76.2 GO:0001533 cornified envelope(GO:0001533)
1.4 16.4 GO:0036038 MKS complex(GO:0036038)
1.3 22.3 GO:0042589 zymogen granule membrane(GO:0042589)
1.3 57.7 GO:0009925 basal plasma membrane(GO:0009925)
1.2 23.3 GO:0097225 sperm midpiece(GO:0097225)
1.2 12.0 GO:0097486 multivesicular body lumen(GO:0097486)
1.2 10.4 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
1.1 16.4 GO:0030478 actin cap(GO:0030478)
0.9 6.5 GO:0001939 female pronucleus(GO:0001939)
0.9 7.0 GO:0045179 apical cortex(GO:0045179)
0.9 5.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.8 4.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.8 8.9 GO:0042583 chromaffin granule(GO:0042583)
0.8 10.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.7 2.2 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.7 54.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.7 29.9 GO:0031904 endosome lumen(GO:0031904)
0.7 47.1 GO:0005882 intermediate filament(GO:0005882)
0.7 15.7 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.6 15.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.6 16.7 GO:0032982 myosin filament(GO:0032982)
0.6 8.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.6 115.4 GO:0072562 blood microparticle(GO:0072562)
0.6 10.6 GO:0042599 lamellar body(GO:0042599)
0.6 4.4 GO:0005610 laminin-5 complex(GO:0005610)
0.5 29.1 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.5 19.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.5 16.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.5 4.8 GO:0005916 fascia adherens(GO:0005916)
0.5 5.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.5 12.0 GO:0034451 centriolar satellite(GO:0034451)
0.5 1.4 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.4 1.3 GO:0033565 ESCRT-0 complex(GO:0033565)
0.4 5.6 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.4 12.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.4 2.9 GO:0030057 desmosome(GO:0030057)
0.4 15.8 GO:1904115 axon cytoplasm(GO:1904115)
0.4 25.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.4 5.9 GO:0016514 SWI/SNF complex(GO:0016514)
0.3 130.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.3 3.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.3 351.6 GO:0005615 extracellular space(GO:0005615)
0.3 9.7 GO:0005796 Golgi lumen(GO:0005796)
0.2 2.0 GO:0042788 polysomal ribosome(GO:0042788)
0.2 2.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 12.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.2 5.7 GO:0031430 M band(GO:0031430)
0.2 10.1 GO:0005811 lipid particle(GO:0005811)
0.2 9.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.2 4.3 GO:0000795 synaptonemal complex(GO:0000795)
0.2 112.0 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 1.0 GO:0097470 ribbon synapse(GO:0097470)
0.1 3.0 GO:0005921 gap junction(GO:0005921)
0.1 4.0 GO:0002102 podosome(GO:0002102)
0.1 5.8 GO:0034707 chloride channel complex(GO:0034707)
0.1 2.1 GO:0005844 polysome(GO:0005844)
0.1 7.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 3.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 6.6 GO:0016605 PML body(GO:0016605)
0.1 3.4 GO:0005901 caveola(GO:0005901)
0.0 1.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.5 GO:0031526 brush border membrane(GO:0031526)
0.0 5.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.9 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 18.1 GO:0009986 cell surface(GO:0009986)
0.0 7.4 GO:0005769 early endosome(GO:0005769)
0.0 1.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.7 GO:0005902 microvillus(GO:0005902)
0.0 0.9 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.2 GO:0005741 mitochondrial outer membrane(GO:0005741)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
19.7 59.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
14.2 56.9 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
12.7 38.1 GO:0005148 prolactin receptor binding(GO:0005148)
12.1 157.4 GO:0005344 oxygen transporter activity(GO:0005344)
9.6 28.7 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
5.6 16.7 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
5.0 20.2 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
4.0 32.2 GO:1990932 5.8S rRNA binding(GO:1990932)
4.0 7.9 GO:0047023 androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
4.0 15.8 GO:0015254 glycerol channel activity(GO:0015254)
3.9 15.6 GO:0035473 lipase binding(GO:0035473)
3.8 11.3 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
3.4 16.9 GO:0042289 MHC class II protein binding(GO:0042289)
3.1 24.6 GO:0001849 complement component C1q binding(GO:0001849)
2.7 8.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
2.6 10.4 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
2.5 7.5 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
2.5 7.5 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
2.5 12.4 GO:0004995 tachykinin receptor activity(GO:0004995)
2.4 25.9 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
2.2 6.5 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
2.0 31.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
2.0 5.9 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
1.6 9.7 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
1.6 8.0 GO:0004771 sterol esterase activity(GO:0004771)
1.5 12.4 GO:0004111 creatine kinase activity(GO:0004111)
1.5 29.0 GO:0003708 retinoic acid receptor activity(GO:0003708)
1.5 9.1 GO:1990254 keratin filament binding(GO:1990254)
1.5 8.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
1.5 5.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.4 18.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
1.4 5.7 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
1.4 8.3 GO:0045569 TRAIL binding(GO:0045569)
1.4 16.4 GO:0045159 myosin II binding(GO:0045159)
1.3 22.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
1.3 6.3 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
1.2 158.5 GO:0005179 hormone activity(GO:0005179)
1.2 4.9 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
1.2 8.5 GO:0035374 chondroitin sulfate binding(GO:0035374)
1.2 86.4 GO:0050840 extracellular matrix binding(GO:0050840)
1.2 11.7 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
1.2 5.8 GO:0070097 delta-catenin binding(GO:0070097)
1.1 8.9 GO:0039706 co-receptor binding(GO:0039706)
1.1 12.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.1 9.7 GO:0005000 vasopressin receptor activity(GO:0005000)
1.1 19.3 GO:0019864 IgG binding(GO:0019864)
1.1 13.8 GO:0015250 water channel activity(GO:0015250)
1.0 28.2 GO:0005212 structural constituent of eye lens(GO:0005212)
1.0 10.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.9 6.6 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.9 17.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.9 32.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.9 20.3 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.9 30.0 GO:0042056 chemoattractant activity(GO:0042056)
0.9 7.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.8 17.0 GO:0070628 proteasome binding(GO:0070628)
0.8 5.6 GO:0051434 BH3 domain binding(GO:0051434)
0.8 4.6 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.7 44.0 GO:0004601 peroxidase activity(GO:0004601)
0.7 8.2 GO:0008061 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.7 19.3 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.7 10.0 GO:0031432 titin binding(GO:0031432)
0.7 12.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.7 5.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.7 58.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.6 10.3 GO:0016004 phospholipase activator activity(GO:0016004)
0.6 7.0 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.6 10.5 GO:0008494 translation activator activity(GO:0008494)
0.6 1.8 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.6 96.4 GO:0002020 protease binding(GO:0002020)
0.6 47.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.6 8.7 GO:0016918 retinal binding(GO:0016918)
0.6 3.4 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.6 15.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.5 4.8 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.5 11.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.5 38.7 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.5 3.4 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.5 6.3 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.5 7.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.5 8.1 GO:0051787 misfolded protein binding(GO:0051787)
0.5 2.9 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.5 10.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.4 4.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.4 12.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.4 13.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.4 5.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.4 3.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.4 3.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.4 2.3 GO:0017018 myosin phosphatase activity(GO:0017018)
0.4 4.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.4 7.4 GO:0016208 AMP binding(GO:0016208)
0.4 6.6 GO:0010857 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.4 1.8 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.4 3.9 GO:0050786 RAGE receptor binding(GO:0050786)
0.3 8.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.3 6.8 GO:0017091 AU-rich element binding(GO:0017091)
0.3 2.0 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.3 19.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.3 2.5 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.3 1.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.3 2.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.3 0.6 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.3 31.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.3 3.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.3 1.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.3 1.4 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.3 2.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.3 5.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.3 26.9 GO:0019905 syntaxin binding(GO:0019905)
0.3 1.6 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.3 2.6 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.2 4.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.2 4.7 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2 7.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.2 4.5 GO:0017081 chloride channel regulator activity(GO:0017081)
0.2 4.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 5.5 GO:0004623 phospholipase A2 activity(GO:0004623)
0.2 8.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 7.4 GO:0005504 fatty acid binding(GO:0005504)
0.2 23.8 GO:0005178 integrin binding(GO:0005178)
0.2 2.4 GO:0015245 fatty acid transporter activity(GO:0015245)
0.2 0.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 3.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 10.2 GO:0019843 rRNA binding(GO:0019843)
0.2 2.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 22.8 GO:0017124 SH3 domain binding(GO:0017124)
0.1 17.9 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 2.0 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 0.9 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.1 1.0 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 1.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 3.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 30.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 19.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 5.7 GO:0050681 androgen receptor binding(GO:0050681)
0.1 9.6 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 87.3 GO:0008270 zinc ion binding(GO:0008270)
0.1 0.9 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 77.1 GO:0005198 structural molecule activity(GO:0005198)
0.1 3.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.4 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 7.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 7.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 6.8 GO:0019003 GDP binding(GO:0019003)
0.1 2.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 1.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.9 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 4.7 GO:0016782 transferase activity, transferring sulfur-containing groups(GO:0016782)
0.1 0.9 GO:0005537 mannose binding(GO:0005537)
0.1 0.6 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 2.5 GO:0035064 methylated histone binding(GO:0035064)
0.1 18.9 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 1.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 2.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 5.9 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 20.2 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.7 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 1.1 GO:0004385 guanylate kinase activity(GO:0004385) ionotropic glutamate receptor binding(GO:0035255)
0.0 10.9 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 11.4 GO:0008289 lipid binding(GO:0008289)
0.0 5.3 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 1.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 9.2 GO:0019901 protein kinase binding(GO:0019901)
0.0 4.6 GO:0030246 carbohydrate binding(GO:0030246)
0.0 2.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.2 GO:0008083 growth factor activity(GO:0008083)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 82.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
2.2 50.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
1.8 28.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
1.6 114.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
1.4 12.5 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
1.2 30.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.8 14.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.7 20.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.7 50.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.7 27.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.7 29.4 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.7 19.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.6 32.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.6 49.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.6 18.5 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.6 19.1 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.6 16.4 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.6 11.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.6 30.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.5 38.2 PID IL4 2PATHWAY IL4-mediated signaling events
0.5 7.0 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.5 15.0 PID IL23 PATHWAY IL23-mediated signaling events
0.5 127.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.5 28.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.5 16.9 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.4 16.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.4 18.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.4 123.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.3 9.4 PID RAS PATHWAY Regulation of Ras family activation
0.3 4.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 5.3 PID IL1 PATHWAY IL1-mediated signaling events
0.2 6.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 11.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2 8.3 PID TRAIL PATHWAY TRAIL signaling pathway
0.2 8.1 PID AP1 PATHWAY AP-1 transcription factor network
0.2 3.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 7.4 PID RHOA PATHWAY RhoA signaling pathway
0.2 5.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.2 10.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.2 6.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.2 7.6 NABA COLLAGENS Genes encoding collagen proteins
0.2 5.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.2 26.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 3.8 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 4.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 4.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 9.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 4.2 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 3.8 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.1 3.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 17.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 4.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 4.3 PID ATR PATHWAY ATR signaling pathway
0.1 3.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0