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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TEAD3_TEAD1

Z-value: 2.74

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Transcription factors associated with TEAD3_TEAD1

Gene Symbol Gene ID Gene Info
TEAD3
ENSG00000007866.14 TEA domain transcription factor 3
TEAD1
ENSG00000187079.10 TEA domain transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TEAD3hg19_v2_chr6_-_35464727_35464738,
hg19_v2_chr6_-_35464817_35464894		0.583.8e-21Click!
TEAD1hg19_v2_chr11_+_12766583_12766592,
hg19_v2_chr11_+_12696102_12696164,
hg19_v2_chr11_+_12695944_12695989		0.532.3e-17Click!

Activity profile of TEAD3_TEAD1 motif

Sorted Z-values of TEAD3_TEAD1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_132272504 208.59 ENST00000367976.3
CTGF
connective tissue growth factor
chr10_-_90712520 124.85 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr1_+_86046433 81.33 ENST00000451137.2
CYR61
cysteine-rich, angiogenic inducer, 61
chr11_-_111781454 64.46 ENST00000533280.1
CRYAB
crystallin, alpha B
chr7_+_134464414 60.30 ENST00000361901.2
CALD1
caldesmon 1
chr5_-_39425068 55.00 ENST00000515700.1
ENST00000339788.6
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr17_-_40575535 54.30 ENST00000357037.5
PTRF
polymerase I and transcript release factor
chr1_-_95391315 54.17 ENST00000545882.1
ENST00000415017.1
CNN3
calponin 3, acidic
chr15_+_63334831 53.57 ENST00000288398.6
ENST00000358278.3
ENST00000560445.1
ENST00000403994.3
ENST00000357980.4
ENST00000559556.1
ENST00000559397.1
ENST00000267996.7
ENST00000560970.1
TPM1
tropomyosin 1 (alpha)
chr2_-_216257849 50.57 ENST00000456923.1
FN1
fibronectin 1
chr4_+_184020398 49.41 ENST00000403733.3
ENST00000378925.3
WWC2
WW and C2 domain containing 2
chr7_+_116165754 48.02 ENST00000405348.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr12_-_7245125 47.99 ENST00000542285.1
ENST00000540610.1
C1R
complement component 1, r subcomponent
chr20_+_35169885 41.58 ENST00000279022.2
ENST00000346786.2
MYL9
myosin, light chain 9, regulatory
chr15_+_39873268 40.99 ENST00000397591.2
ENST00000260356.5
THBS1
thrombospondin 1
chr7_+_134464376 40.78 ENST00000454108.1
ENST00000361675.2
CALD1
caldesmon 1
chr7_+_128470431 40.78 ENST00000325888.8
ENST00000346177.6
FLNC
filamin C, gamma
chr15_+_96869165 38.36 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr6_+_30850697 38.17 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
DDR1
discoidin domain receptor tyrosine kinase 1
chr8_+_144816303 37.45 ENST00000533004.1
FAM83H-AS1
FAM83H antisense RNA 1 (head to head)
chr1_-_1293904 36.48 ENST00000309212.6
ENST00000342753.4
ENST00000445648.2
MXRA8
matrix-remodelling associated 8
chr11_-_111782696 36.03 ENST00000227251.3
ENST00000526180.1
CRYAB
crystallin, alpha B
chr6_+_83073334 35.20 ENST00000369750.3
TPBG
trophoblast glycoprotein
chr5_-_39425222 35.05 ENST00000320816.6
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr7_+_116165038 34.97 ENST00000393470.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr6_+_83072923 34.90 ENST00000535040.1
TPBG
trophoblast glycoprotein
chr11_-_111781610 34.60 ENST00000525823.1
CRYAB
crystallin, alpha B
chr5_-_39425290 34.50 ENST00000545653.1
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr17_+_20059302 32.70 ENST00000395530.2
SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr11_-_111782484 32.43 ENST00000533971.1
CRYAB
crystallin, alpha B
chr3_-_134093275 31.78 ENST00000513145.1
ENST00000422605.2
AMOTL2
angiomotin like 2
chr7_+_100464760 31.46 ENST00000200457.4
TRIP6
thyroid hormone receptor interactor 6
chr4_-_187644930 31.32 ENST00000441802.2
FAT1
FAT atypical cadherin 1
chr11_+_114166536 31.30 ENST00000299964.3
NNMT
nicotinamide N-methyltransferase
chr10_-_33247124 31.28 ENST00000414670.1
ENST00000302278.3
ENST00000374956.4
ENST00000488494.1
ENST00000417122.2
ENST00000474568.1
ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr11_-_111781554 31.17 ENST00000526167.1
ENST00000528961.1
CRYAB
crystallin, alpha B
chr15_-_60690163 31.03 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
ANXA2
annexin A2
chr3_-_134093395 30.15 ENST00000249883.5
AMOTL2
angiomotin like 2
chr3_-_114343039 29.72 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr10_-_99447024 27.32 ENST00000370626.3
AVPI1
arginine vasopressin-induced 1
chr5_-_55290773 26.96 ENST00000502326.3
ENST00000381298.2
IL6ST
interleukin 6 signal transducer (gp130, oncostatin M receptor)
chr1_-_201438282 26.86 ENST00000367311.3
ENST00000367309.1
PHLDA3
pleckstrin homology-like domain, family A, member 3
chrX_-_10588459 26.71 ENST00000380782.2
MID1
midline 1 (Opitz/BBB syndrome)
chr1_-_94050668 24.97 ENST00000539242.1
BCAR3
breast cancer anti-estrogen resistance 3
chr10_+_123872483 23.65 ENST00000369001.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr1_-_16344500 23.49 ENST00000406363.2
ENST00000411503.1
ENST00000545268.1
ENST00000487046.1
HSPB7
heat shock 27kDa protein family, member 7 (cardiovascular)
chr11_-_14379997 23.47 ENST00000526063.1
ENST00000532814.1
RRAS2
related RAS viral (r-ras) oncogene homolog 2
chr3_-_127541194 23.42 ENST00000453507.2
MGLL
monoglyceride lipase
chr7_+_134430212 22.51 ENST00000436461.2
CALD1
caldesmon 1
chr1_-_161279749 22.46 ENST00000533357.1
ENST00000360451.6
ENST00000336559.4
MPZ
myelin protein zero
chr4_-_186733363 22.13 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2
sorbin and SH3 domain containing 2
chr16_-_122619 21.77 ENST00000262316.6
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr11_+_92085707 21.27 ENST00000525166.1
FAT3
FAT atypical cadherin 3
chr6_-_128841503 21.18 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
PTPRK
protein tyrosine phosphatase, receptor type, K
chr19_-_14606900 20.18 ENST00000393029.3
ENST00000393028.1
ENST00000393033.4
ENST00000345425.2
ENST00000586027.1
ENST00000591349.1
ENST00000587210.1
GIPC1
GIPC PDZ domain containing family, member 1
chr11_+_92577506 19.65 ENST00000533797.1
FAT3
FAT atypical cadherin 3
chr19_+_33182823 18.65 ENST00000397061.3
NUDT19
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr12_-_8815299 18.42 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr11_+_66824276 18.36 ENST00000308831.2
RHOD
ras homolog family member D
chr19_+_45409011 18.18 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
APOE
apolipoprotein E
chr1_-_16482554 18.00 ENST00000358432.5
EPHA2
EPH receptor A2
chr12_-_8815215 17.77 ENST00000544889.1
ENST00000543369.1
MFAP5
microfibrillar associated protein 5
chr11_+_92085262 17.51 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT3
FAT atypical cadherin 3
chr3_-_128712955 17.48 ENST00000265068.5
KIAA1257
KIAA1257
chr15_-_48937982 17.29 ENST00000316623.5
FBN1
fibrillin 1
chr4_+_41614909 17.09 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr19_-_17185848 16.59 ENST00000593360.1
HAUS8
HAUS augmin-like complex, subunit 8
chr2_-_190044480 16.53 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr14_-_23904861 16.49 ENST00000355349.3
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chr6_-_35464817 16.21 ENST00000338863.7
TEAD3
TEA domain family member 3
chr6_-_35464727 15.81 ENST00000402886.3
TEAD3
TEA domain family member 3
chr4_+_41614720 15.43 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr17_+_4901199 15.08 ENST00000320785.5
ENST00000574165.1
KIF1C
kinesin family member 1C
chr2_-_217560248 14.83 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr6_-_30712313 14.58 ENST00000376377.2
ENST00000259874.5
IER3
immediate early response 3
chr4_+_169552748 14.45 ENST00000504519.1
ENST00000512127.1
PALLD
palladin, cytoskeletal associated protein
chr1_-_59043166 14.40 ENST00000371225.2
TACSTD2
tumor-associated calcium signal transducer 2
chr20_-_44540686 14.30 ENST00000477313.1
ENST00000542937.1
ENST00000372431.3
ENST00000354050.4
ENST00000420868.2
PLTP
phospholipid transfer protein
chr7_-_137686791 14.01 ENST00000452463.1
ENST00000330387.6
ENST00000456390.1
CREB3L2
cAMP responsive element binding protein 3-like 2
chr3_+_147127142 13.99 ENST00000282928.4
ZIC1
Zic family member 1
chrX_-_10851762 13.94 ENST00000380785.1
ENST00000380787.1
MID1
midline 1 (Opitz/BBB syndrome)
chr11_-_8832182 13.90 ENST00000527510.1
ENST00000528527.1
ENST00000528523.1
ENST00000313726.6
ST5
suppression of tumorigenicity 5
chr19_+_15218180 13.81 ENST00000342784.2
ENST00000597977.1
ENST00000600440.1
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr18_+_21693306 13.40 ENST00000540918.2
TTC39C
tetratricopeptide repeat domain 39C
chr7_+_102715315 13.22 ENST00000428183.2
ENST00000323716.3
ENST00000441711.2
ENST00000454559.1
ENST00000425331.1
ENST00000541300.1
ARMC10
armadillo repeat containing 10
chr1_+_196621002 13.14 ENST00000367429.4
ENST00000439155.2
CFH
complement factor H
chr8_+_70378852 12.98 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
SULF1
sulfatase 1
chr11_-_76381029 12.68 ENST00000407242.2
ENST00000421973.1
LRRC32
leucine rich repeat containing 32
chr8_-_82395461 12.58 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chr17_+_37856299 12.53 ENST00000269571.5
ERBB2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr3_-_185538849 12.49 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr9_-_14314518 12.40 ENST00000397581.2
NFIB
nuclear factor I/B
chr9_-_14314566 12.24 ENST00000397579.2
NFIB
nuclear factor I/B
chr17_-_39677971 12.23 ENST00000393976.2
KRT15
keratin 15
chr19_-_50143452 12.22 ENST00000246792.3
RRAS
related RAS viral (r-ras) oncogene homolog
chr9_+_118916082 12.06 ENST00000328252.3
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr12_-_8815404 11.77 ENST00000359478.2
ENST00000396549.2
MFAP5
microfibrillar associated protein 5
chr7_+_26438187 11.63 ENST00000439120.1
ENST00000430548.1
ENST00000421862.1
ENST00000449537.1
ENST00000420774.1
ENST00000418758.2
AC004540.5
AC004540.5
chr2_+_189157536 11.53 ENST00000409580.1
ENST00000409637.3
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr6_+_134210243 11.51 ENST00000367882.4
TCF21
transcription factor 21
chr2_+_102759199 11.43 ENST00000409288.1
ENST00000410023.1
IL1R1
interleukin 1 receptor, type I
chr2_+_189157498 11.36 ENST00000359135.3
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr3_-_48057890 11.33 ENST00000434267.1
MAP4
microtubule-associated protein 4
chr5_-_43412418 11.15 ENST00000537013.1
ENST00000361115.4
CCL28
chemokine (C-C motif) ligand 28
chr1_+_150229554 10.93 ENST00000369111.4
CA14
carbonic anhydrase XIV
chr12_-_54813229 10.74 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr1_-_229569834 10.73 ENST00000366684.3
ENST00000366683.2
ACTA1
actin, alpha 1, skeletal muscle
chr12_+_27677085 10.71 ENST00000545334.1
ENST00000540114.1
ENST00000537927.1
ENST00000318304.8
ENST00000535047.1
ENST00000542629.1
ENST00000228425.6
PPFIBP1
PTPRF interacting protein, binding protein 1 (liprin beta 1)
chr1_+_196621156 10.66 ENST00000359637.2
CFH
complement factor H
chr15_+_63354769 10.61 ENST00000558910.1
TPM1
tropomyosin 1 (alpha)
chr16_+_30387141 10.42 ENST00000566955.1
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr4_-_186877806 10.32 ENST00000355634.5
SORBS2
sorbin and SH3 domain containing 2
chr3_-_149375783 10.18 ENST00000467467.1
ENST00000460517.1
ENST00000360632.3
WWTR1
WW domain containing transcription regulator 1
chr17_+_37856253 10.06 ENST00000540147.1
ENST00000584450.1
ERBB2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr5_+_140868717 9.98 ENST00000252087.1
PCDHGC5
protocadherin gamma subfamily C, 5
chr10_-_33625154 9.93 ENST00000265371.4
NRP1
neuropilin 1
chr13_-_33760216 9.86 ENST00000255486.4
STARD13
StAR-related lipid transfer (START) domain containing 13
chr17_-_73505961 9.81 ENST00000433559.2
CASKIN2
CASK interacting protein 2
chr12_-_111358372 9.71 ENST00000548438.1
ENST00000228841.8
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr11_+_46299199 9.68 ENST00000529193.1
ENST00000288400.3
CREB3L1
cAMP responsive element binding protein 3-like 1
chr4_+_176986978 9.67 ENST00000508596.1
ENST00000393643.2
WDR17
WD repeat domain 17
chr8_+_97597148 9.60 ENST00000521590.1
SDC2
syndecan 2
chr4_-_186877502 9.46 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
SORBS2
sorbin and SH3 domain containing 2
chr1_-_94079648 9.29 ENST00000370247.3
BCAR3
breast cancer anti-estrogen resistance 3
chr1_+_114522049 9.24 ENST00000369551.1
ENST00000320334.4
OLFML3
olfactomedin-like 3
chr9_-_16727978 9.14 ENST00000418777.1
ENST00000468187.2
BNC2
basonuclin 2
chr17_-_73511584 9.10 ENST00000321617.3
CASKIN2
CASK interacting protein 2
chr11_-_111170526 9.10 ENST00000355430.4
COLCA1
colorectal cancer associated 1
chr18_+_3247779 8.89 ENST00000578611.1
ENST00000583449.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr10_-_17659234 8.83 ENST00000466335.1
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr18_-_25616519 8.76 ENST00000399380.3
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr17_-_39093672 8.58 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr1_+_62417957 8.57 ENST00000307297.7
ENST00000543708.1
INADL
InaD-like (Drosophila)
chr1_-_11918988 8.50 ENST00000376468.3
NPPB
natriuretic peptide B
chr1_-_201915590 8.48 ENST00000367288.4
LMOD1
leiomodin 1 (smooth muscle)
chr8_-_38325219 8.35 ENST00000533668.1
ENST00000413133.2
ENST00000397108.4
ENST00000526742.1
ENST00000525001.1
ENST00000425967.3
ENST00000529552.1
ENST00000397113.2
FGFR1
fibroblast growth factor receptor 1
chr17_+_57232690 8.04 ENST00000262293.4
PRR11
proline rich 11
chr18_+_3247413 7.96 ENST00000579226.1
ENST00000217652.3
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr17_+_70117153 7.89 ENST00000245479.2
SOX9
SRY (sex determining region Y)-box 9
chr6_+_118869452 7.85 ENST00000357525.5
PLN
phospholamban
chr16_+_30386098 7.79 ENST00000322861.7
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr5_-_150138551 7.70 ENST00000446090.2
ENST00000447998.2
DCTN4
dynactin 4 (p62)
chr15_+_33010175 7.65 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
GREM1
gremlin 1, DAN family BMP antagonist
chr6_+_148663729 7.64 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1
chr2_+_30569506 7.57 ENST00000421976.2
AC109642.1
AC109642.1
chr6_-_3157760 7.54 ENST00000333628.3
TUBB2A
tubulin, beta 2A class IIa
chr19_+_39138320 7.53 ENST00000424234.2
ENST00000390009.3
ENST00000589528.1
ACTN4
actinin, alpha 4
chr8_-_119124045 7.52 ENST00000378204.2
EXT1
exostosin glycosyltransferase 1
chr17_+_73717551 7.44 ENST00000450894.3
ITGB4
integrin, beta 4
chr9_-_113341985 7.31 ENST00000374469.1
SVEP1
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr9_-_14308004 7.28 ENST00000493697.1
NFIB
nuclear factor I/B
chr17_+_73717407 7.28 ENST00000579662.1
ITGB4
integrin, beta 4
chr15_+_74466744 7.27 ENST00000560862.1
ENST00000395118.1
ISLR
immunoglobulin superfamily containing leucine-rich repeat
chr4_-_186732048 7.16 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chr12_+_52445191 7.06 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr11_-_47470703 7.00 ENST00000298854.2
RAPSN
receptor-associated protein of the synapse
chr11_+_111782934 7.00 ENST00000304298.3
HSPB2
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr11_+_46316677 6.98 ENST00000534787.1
CREB3L1
cAMP responsive element binding protein 3-like 1
chr19_+_39138271 6.96 ENST00000252699.2
ACTN4
actinin, alpha 4
chr19_+_676385 6.95 ENST00000166139.4
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr7_+_30960915 6.85 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
AQP1
aquaporin 1 (Colton blood group)
chr2_-_211179883 6.82 ENST00000352451.3
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr11_-_47470682 6.80 ENST00000529341.1
ENST00000352508.3
RAPSN
receptor-associated protein of the synapse
chr18_+_7754957 6.76 ENST00000400053.4
PTPRM
protein tyrosine phosphatase, receptor type, M
chr9_+_139873264 6.66 ENST00000446677.1
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr4_+_166300084 6.62 ENST00000402744.4
CPE
carboxypeptidase E
chr15_+_41136216 6.49 ENST00000562057.1
ENST00000344051.4
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr9_-_13175823 6.48 ENST00000545857.1
MPDZ
multiple PDZ domain protein
chr15_+_41136586 6.38 ENST00000431806.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr4_+_165675269 6.35 ENST00000507311.1
RP11-294O2.2
RP11-294O2.2
chrX_-_41449204 6.18 ENST00000378179.3
CASK
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr12_+_32655048 6.09 ENST00000427716.2
ENST00000266482.3
FGD4
FYVE, RhoGEF and PH domain containing 4
chr7_-_135412925 6.08 ENST00000354042.4
SLC13A4
solute carrier family 13 (sodium/sulfate symporter), member 4
chr9_+_112542572 6.04 ENST00000374530.3
PALM2-AKAP2
PALM2-AKAP2 readthrough
chr8_-_141728760 6.03 ENST00000430260.2
PTK2
protein tyrosine kinase 2
chr12_-_104443890 6.01 ENST00000547583.1
ENST00000360814.4
ENST00000546851.1
GLT8D2
glycosyltransferase 8 domain containing 2
chr3_+_38347427 5.96 ENST00000273173.4
SLC22A14
solute carrier family 22, member 14
chr11_+_101981169 5.95 ENST00000526343.1
ENST00000282441.5
ENST00000537274.1
ENST00000345877.2
YAP1
Yes-associated protein 1
chr11_-_47470591 5.91 ENST00000524487.1
RAPSN
receptor-associated protein of the synapse
chr10_+_123923205 5.87 ENST00000369004.3
ENST00000260733.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr19_+_782755 5.86 ENST00000606242.1
ENST00000586061.1
AC006273.5
AC006273.5
chr14_+_32546485 5.78 ENST00000345122.3
ENST00000432921.1
ENST00000433497.1
ARHGAP5
Rho GTPase activating protein 5
chr4_-_175443943 5.77 ENST00000296522.6
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr9_+_131314859 5.76 ENST00000358161.5
ENST00000372731.4
ENST00000372739.3
SPTAN1
spectrin, alpha, non-erythrocytic 1
chr4_+_25657444 5.75 ENST00000504570.1
ENST00000382051.3
SLC34A2
solute carrier family 34 (type II sodium/phosphate contransporter), member 2
chr1_+_119957554 5.68 ENST00000543831.1
ENST00000433745.1
ENST00000369416.3
HSD3B2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chrX_-_135333514 5.66 ENST00000370661.1
ENST00000370660.3
MAP7D3
MAP7 domain containing 3
chr14_-_89021077 5.58 ENST00000556564.1
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr14_+_74035763 5.57 ENST00000238651.5
ACOT2
acyl-CoA thioesterase 2
chr1_+_26503894 5.57 ENST00000361530.6
ENST00000374253.5
CNKSR1
connector enhancer of kinase suppressor of Ras 1
chr19_-_49371711 5.53 ENST00000355496.5
ENST00000263265.6
PLEKHA4
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr12_+_3068466 5.51 ENST00000358409.2
TEAD4
TEA domain family member 4
chr7_-_83278322 5.51 ENST00000307792.3
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr8_+_120079478 5.48 ENST00000332843.2
COLEC10
collectin sub-family member 10 (C-type lectin)
chr2_+_32502952 5.43 ENST00000238831.4
YIPF4
Yip1 domain family, member 4
chr1_+_100818484 5.42 ENST00000544534.1
CDC14A
cell division cycle 14A
chr14_-_23877474 5.38 ENST00000405093.3
MYH6
myosin, heavy chain 6, cardiac muscle, alpha
chr1_+_152974218 5.37 ENST00000331860.3
ENST00000443178.1
ENST00000295367.4
SPRR3
small proline-rich protein 3
chr5_+_54455946 5.34 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
GPX8
glutathione peroxidase 8 (putative)
chr10_+_104005272 5.30 ENST00000369983.3
GBF1
golgi brefeldin A resistant guanine nucleotide exchange factor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TEAD3_TEAD1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
69.5 208.6 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
31.1 124.5 GO:0035026 leading edge cell differentiation(GO:0035026)
27.7 83.0 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
22.6 135.6 GO:0090131 mesenchyme migration(GO:0090131)
16.9 50.6 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
13.7 41.0 GO:0002605 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
11.0 198.7 GO:0007021 tubulin complex assembly(GO:0007021)
10.4 31.3 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
10.3 31.0 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
9.6 38.4 GO:0009956 radial pattern formation(GO:0009956)
9.1 18.2 GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803)
9.0 81.3 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278) chondroblast differentiation(GO:0060591)
9.0 18.0 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
8.4 33.7 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
8.0 64.2 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
7.9 7.9 GO:0072197 ureter urothelium development(GO:0072190) ureter morphogenesis(GO:0072197)
6.6 19.7 GO:1900073 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
6.4 25.6 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
6.3 31.5 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
5.4 27.1 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
5.3 32.0 GO:0055059 asymmetric neuroblast division(GO:0055059)
4.9 14.8 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
4.8 14.5 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
4.6 31.9 GO:0021740 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
4.4 22.0 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
4.2 38.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
4.1 16.5 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
3.8 11.5 GO:0072276 branchiomeric skeletal muscle development(GO:0014707) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
3.8 11.4 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
3.6 14.3 GO:0042360 vitamin E metabolic process(GO:0042360)
3.5 17.3 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
3.5 13.8 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
3.3 23.4 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
3.1 40.6 GO:0035372 protein localization to microtubule(GO:0035372)
2.9 66.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
2.8 8.4 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
2.8 8.4 GO:1903465 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
2.8 16.7 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
2.6 31.3 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
2.5 15.2 GO:0051012 microtubule sliding(GO:0051012)
2.3 4.6 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
2.3 6.9 GO:0072019 carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229) metanephric proximal tubule development(GO:0072237)
2.2 15.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
2.2 11.2 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
2.2 6.6 GO:0032971 regulation of muscle filament sliding(GO:0032971)
2.2 11.1 GO:0010587 miRNA catabolic process(GO:0010587)
2.2 13.0 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
2.1 36.5 GO:0060856 establishment of blood-brain barrier(GO:0060856)
2.1 87.7 GO:0035329 hippo signaling(GO:0035329)
2.1 12.7 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
2.0 4.0 GO:0021943 formation of radial glial scaffolds(GO:0021943)
2.0 2.0 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
2.0 9.9 GO:0060301 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
2.0 9.9 GO:0097498 endothelial tube lumen extension(GO:0097498)
2.0 11.8 GO:1901631 positive regulation of presynaptic membrane organization(GO:1901631)
2.0 27.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
1.9 7.6 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
1.8 3.6 GO:0061386 closure of optic fissure(GO:0061386)
1.8 3.6 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
1.8 60.7 GO:0060216 definitive hemopoiesis(GO:0060216)
1.6 34.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
1.6 4.8 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
1.6 3.2 GO:1901228 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
1.5 49.1 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
1.4 8.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
1.4 6.9 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
1.4 9.6 GO:0008218 bioluminescence(GO:0008218)
1.4 4.1 GO:0007538 primary sex determination(GO:0007538)
1.3 4.0 GO:0046533 negative regulation of photoreceptor cell differentiation(GO:0046533)
1.3 5.3 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
1.3 6.6 GO:0030070 insulin processing(GO:0030070)
1.3 8.9 GO:0060480 lung goblet cell differentiation(GO:0060480)
1.3 3.8 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
1.3 2.5 GO:0031133 regulation of axon diameter(GO:0031133)
1.2 9.7 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
1.2 4.6 GO:0035720 intraciliary anterograde transport(GO:0035720)
1.1 4.6 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
1.1 3.3 GO:0036071 N-glycan fucosylation(GO:0036071)
1.1 3.2 GO:0060214 endocardium formation(GO:0060214)
1.1 14.8 GO:0035878 nail development(GO:0035878)
1.0 5.2 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
1.0 23.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
1.0 3.0 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
1.0 10.7 GO:1903672 positive regulation of sprouting angiogenesis(GO:1903672)
1.0 2.9 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
1.0 1.9 GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332)
1.0 1.9 GO:0048263 determination of dorsal identity(GO:0048263)
1.0 3.8 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.9 7.5 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.9 9.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.9 8.4 GO:0006477 protein sulfation(GO:0006477)
0.9 70.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.9 3.7 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.9 3.6 GO:0072660 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.9 8.2 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.9 5.4 GO:0003228 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.9 3.5 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.8 8.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.8 3.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.8 3.4 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.8 3.3 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.8 46.3 GO:0048747 muscle fiber development(GO:0048747)
0.8 2.5 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.8 18.5 GO:0098743 cell aggregation(GO:0098743)
0.8 12.3 GO:0007097 nuclear migration(GO:0007097)
0.7 20.2 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.7 14.5 GO:0003334 keratinocyte development(GO:0003334)
0.7 5.8 GO:2001300 lipoxin metabolic process(GO:2001300)
0.7 12.9 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.7 4.3 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.7 2.8 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.7 5.6 GO:0007266 Rho protein signal transduction(GO:0007266)
0.7 4.8 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.7 2.0 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.7 103.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.7 6.0 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.7 9.9 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.6 56.8 GO:0070527 platelet aggregation(GO:0070527)
0.6 10.0 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.6 1.9 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.6 1.8 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.6 1.2 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.6 1.7 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.5 2.7 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.5 2.1 GO:0023021 glucosylceramide catabolic process(GO:0006680) termination of signal transduction(GO:0023021) beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.5 2.1 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.5 3.6 GO:0031642 negative regulation of myelination(GO:0031642)
0.5 10.3 GO:0003416 endochondral bone growth(GO:0003416)
0.5 3.0 GO:0060346 bone trabecula formation(GO:0060346)
0.5 9.8 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.5 12.2 GO:0060325 face morphogenesis(GO:0060325)
0.5 4.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.5 20.7 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.5 1.4 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.5 1.8 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.5 2.7 GO:0015811 L-cystine transport(GO:0015811)
0.5 5.0 GO:0008272 sulfate transport(GO:0008272)
0.5 2.3 GO:0030035 microspike assembly(GO:0030035)
0.4 4.0 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.4 6.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.4 3.5 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.4 5.7 GO:0006702 androgen biosynthetic process(GO:0006702)
0.4 9.1 GO:0050872 white fat cell differentiation(GO:0050872)
0.4 48.0 GO:0030449 regulation of complement activation(GO:0030449)
0.4 5.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.4 2.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.4 3.5 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.4 3.5 GO:0051451 myoblast migration(GO:0051451)
0.4 8.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.4 2.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.4 26.2 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.4 3.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.3 1.7 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.3 27.4 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.3 3.0 GO:0060242 contact inhibition(GO:0060242)
0.3 2.0 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.3 1.0 GO:0006434 seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.3 1.9 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.3 3.7 GO:0015671 oxygen transport(GO:0015671)
0.3 2.6 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.3 25.9 GO:0070268 cornification(GO:0070268)
0.3 117.9 GO:0006936 muscle contraction(GO:0006936)
0.3 12.4 GO:0015701 bicarbonate transport(GO:0015701)
0.3 2.1 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.3 3.1 GO:0045475 locomotor rhythm(GO:0045475)
0.3 1.5 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.2 1.7 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 1.5 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.2 0.7 GO:0006711 estrogen catabolic process(GO:0006711)
0.2 0.7 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.2 3.1 GO:0051764 actin crosslink formation(GO:0051764)
0.2 2.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.2 21.8 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.2 26.0 GO:0021987 cerebral cortex development(GO:0021987)
0.2 1.1 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.2 0.9 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.2 5.6 GO:0006825 copper ion transport(GO:0006825)
0.2 4.5 GO:1901798 positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.2 4.2 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.2 13.5 GO:0042472 inner ear morphogenesis(GO:0042472)
0.2 2.6 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.2 2.6 GO:2000394 phosphatidylcholine catabolic process(GO:0034638) positive regulation of lamellipodium morphogenesis(GO:2000394)
0.2 21.7 GO:0051225 spindle assembly(GO:0051225)
0.2 23.5 GO:0000187 activation of MAPK activity(GO:0000187)
0.2 1.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.2 0.5 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.2 27.2 GO:0031032 actomyosin structure organization(GO:0031032)
0.2 15.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.2 16.8 GO:0009062 fatty acid catabolic process(GO:0009062)
0.2 0.5 GO:0045112 integrin biosynthetic process(GO:0045112) regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.2 1.0 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.2 2.2 GO:0030220 platelet formation(GO:0030220)
0.2 2.5 GO:0006751 glutathione catabolic process(GO:0006751)
0.2 12.3 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.2 4.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.2 1.9 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.2 5.7 GO:0046785 microtubule polymerization(GO:0046785)
0.2 5.6 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.2 31.4 GO:0006986 response to unfolded protein(GO:0006986)
0.2 6.2 GO:0008542 visual learning(GO:0008542)
0.1 0.7 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 1.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 2.4 GO:0006590 thyroid hormone generation(GO:0006590)
0.1 0.5 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 5.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 2.5 GO:0031638 zymogen activation(GO:0031638)
0.1 4.0 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.1 0.8 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 11.5 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.1 1.3 GO:0042346 positive regulation of NF-kappaB import into nucleus(GO:0042346)
0.1 5.1 GO:0021549 cerebellum development(GO:0021549)
0.1 1.6 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.1 1.2 GO:0005980 glycogen catabolic process(GO:0005980)
0.1 1.8 GO:0016540 protein autoprocessing(GO:0016540)
0.1 10.7 GO:0002576 platelet degranulation(GO:0002576)
0.1 0.8 GO:0098719 gastric acid secretion(GO:0001696) sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.4 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 1.2 GO:0007605 sensory perception of sound(GO:0007605)
0.1 4.0 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 0.8 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.9 GO:0061037 negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037)
0.1 2.0 GO:0015695 organic cation transport(GO:0015695)
0.1 1.2 GO:0010761 fibroblast migration(GO:0010761)
0.1 3.3 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.1 0.1 GO:0070638 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.1 8.8 GO:0001649 osteoblast differentiation(GO:0001649)
0.1 0.5 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 5.3 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.1 5.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.7 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.1 0.3 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 1.0 GO:0030252 growth hormone secretion(GO:0030252)
0.1 0.7 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.7 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1 1.6 GO:0007052 mitotic spindle organization(GO:0007052)
0.1 1.1 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 1.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.8 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 1.9 GO:0046847 filopodium assembly(GO:0046847)
0.0 1.5 GO:0051693 actin filament capping(GO:0051693)
0.0 2.7 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 3.5 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.1 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 2.8 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 2.6 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 0.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.9 GO:0051646 mitochondrion localization(GO:0051646)
0.0 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.0 1.6 GO:0030879 mammary gland development(GO:0030879)
0.0 0.1 GO:0044254 angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266)
0.0 0.1 GO:2000510 positive regulation of sperm motility involved in capacitation(GO:0060474) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0 0.7 GO:0006479 protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.0 0.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 2.9 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
31.2 124.9 GO:0030485 smooth muscle contractile fiber(GO:0030485)
13.8 124.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
13.5 215.8 GO:0097512 cardiac myofibril(GO:0097512)
10.4 31.3 GO:0034680 integrin alpha3-beta1 complex(GO:0034667) integrin alpha8-beta1 complex(GO:0034678) integrin alpha10-beta1 complex(GO:0034680)
6.9 90.0 GO:0005577 fibrinogen complex(GO:0005577)
6.5 97.9 GO:0030478 actin cap(GO:0030478)
6.3 31.5 GO:0045323 interleukin-1 receptor complex(GO:0045323)
6.2 31.0 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
6.2 24.6 GO:0005896 interleukin-6 receptor complex(GO:0005896)
6.1 18.2 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
5.7 80.0 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
5.5 16.5 GO:0005588 collagen type V trimer(GO:0005588)
3.8 64.2 GO:0032059 bleb(GO:0032059)
3.6 213.6 GO:0005801 cis-Golgi network(GO:0005801)
3.3 72.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
2.7 10.7 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
2.7 31.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
2.5 89.0 GO:0005859 muscle myosin complex(GO:0005859)
2.3 6.9 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
2.2 19.7 GO:0099634 postsynaptic specialization membrane(GO:0099634)
2.0 9.9 GO:0060091 kinocilium(GO:0060091)
1.8 16.6 GO:0070652 HAUS complex(GO:0070652)
1.7 3.4 GO:1990584 cardiac Troponin complex(GO:1990584)
1.6 14.8 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
1.6 4.7 GO:0005607 laminin-2 complex(GO:0005607)
1.5 4.6 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
1.4 4.3 GO:0000806 Y chromosome(GO:0000806) cyclin A2-CDK2 complex(GO:0097124)
1.3 4.0 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
1.3 4.0 GO:0031523 Myb complex(GO:0031523)
1.2 5.9 GO:0071148 TEAD-1-YAP complex(GO:0071148)
1.1 12.0 GO:0002116 semaphorin receptor complex(GO:0002116)
1.0 14.8 GO:0030056 hemidesmosome(GO:0030056)
0.9 45.5 GO:0043034 costamere(GO:0043034)
0.8 12.3 GO:0005869 dynactin complex(GO:0005869)
0.8 8.8 GO:0005916 fascia adherens(GO:0005916)
0.8 3.1 GO:0016600 flotillin complex(GO:0016600)
0.7 22.7 GO:0009925 basal plasma membrane(GO:0009925)
0.7 4.8 GO:0001520 outer dense fiber(GO:0001520)
0.7 16.5 GO:0031143 pseudopodium(GO:0031143)
0.6 41.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.6 5.4 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.6 61.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.5 9.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.5 19.2 GO:0005865 striated muscle thin filament(GO:0005865)
0.5 1.6 GO:0031262 Ndc80 complex(GO:0031262)
0.5 7.6 GO:0043234 protein complex(GO:0043234)
0.5 4.0 GO:0042788 polysomal ribosome(GO:0042788)
0.5 7.8 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.4 3.6 GO:0005610 laminin-5 complex(GO:0005610)
0.4 179.0 GO:0016324 apical plasma membrane(GO:0016324)
0.4 2.6 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.4 3.8 GO:0005579 membrane attack complex(GO:0005579)
0.4 2.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.4 36.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.4 75.5 GO:0072562 blood microparticle(GO:0072562)
0.4 20.0 GO:0016235 aggresome(GO:0016235)
0.4 6.2 GO:0005652 nuclear lamina(GO:0005652)
0.4 126.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.4 27.3 GO:0005811 lipid particle(GO:0005811)
0.3 14.5 GO:0002102 podosome(GO:0002102)
0.3 13.3 GO:0043198 dendritic shaft(GO:0043198)
0.3 29.1 GO:0030175 filopodium(GO:0030175)
0.3 15.1 GO:0005871 kinesin complex(GO:0005871)
0.3 2.1 GO:0033269 internode region of axon(GO:0033269)
0.3 2.0 GO:0097209 epidermal lamellar body(GO:0097209)
0.3 2.5 GO:0043083 synaptic cleft(GO:0043083)
0.3 15.0 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3 11.2 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.3 0.5 GO:0071437 invadopodium(GO:0071437) invadopodium membrane(GO:0071438)
0.2 20.5 GO:0005882 intermediate filament(GO:0005882)
0.2 21.0 GO:0032587 ruffle membrane(GO:0032587)
0.2 17.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.2 3.1 GO:0031941 filamentous actin(GO:0031941)
0.2 2.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 1.8 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 1.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 12.4 GO:0072686 mitotic spindle(GO:0072686)
0.2 6.7 GO:0016459 myosin complex(GO:0016459)
0.2 6.6 GO:0001533 cornified envelope(GO:0001533)
0.2 1.4 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 5.0 GO:0097542 ciliary tip(GO:0097542)
0.2 3.5 GO:0033268 node of Ranvier(GO:0033268)
0.2 10.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 0.9 GO:0097427 microtubule bundle(GO:0097427)
0.1 3.3 GO:0035869 ciliary transition zone(GO:0035869)
0.1 1.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 5.5 GO:0005581 collagen trimer(GO:0005581)
0.1 1.5 GO:0008091 spectrin(GO:0008091)
0.1 0.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 6.2 GO:0042641 actomyosin(GO:0042641)
0.1 1.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 4.5 GO:0030863 cortical cytoskeleton(GO:0030863)
0.1 3.7 GO:0036064 ciliary basal body(GO:0036064)
0.1 6.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 11.9 GO:0001650 fibrillar center(GO:0001650)
0.1 92.8 GO:0005783 endoplasmic reticulum(GO:0005783)
0.1 76.9 GO:0005615 extracellular space(GO:0005615)
0.1 1.1 GO:0042629 mast cell granule(GO:0042629)
0.1 0.9 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 11.2 GO:0005769 early endosome(GO:0005769)
0.0 1.3 GO:0045177 apical part of cell(GO:0045177)
0.0 2.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 6.9 GO:0005874 microtubule(GO:0005874)
0.0 10.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.3 GO:0044215 host(GO:0018995) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.4 GO:0005771 multivesicular body(GO:0005771)
0.0 1.5 GO:0005770 late endosome(GO:0005770)
0.0 0.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.4 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0071004 U2-type prespliceosome(GO:0071004)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
27.7 83.0 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
13.7 41.0 GO:0070052 collagen V binding(GO:0070052)
11.2 33.7 GO:0004924 oncostatin-M receptor activity(GO:0004924)
10.9 261.6 GO:0001968 fibronectin binding(GO:0001968)
7.8 31.3 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
7.6 38.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
6.4 196.9 GO:0005212 structural constituent of eye lens(GO:0005212)
6.1 18.2 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
5.8 127.1 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
5.2 31.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
4.9 136.3 GO:0005523 tropomyosin binding(GO:0005523)
3.2 13.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
3.1 96.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
2.9 46.4 GO:0032036 myosin heavy chain binding(GO:0032036)
2.9 11.4 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
2.7 26.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
2.6 18.4 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
2.5 20.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
2.5 10.0 GO:0038132 neuregulin binding(GO:0038132)
2.5 27.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
2.5 54.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
2.3 6.9 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
2.0 7.8 GO:0042030 ATPase inhibitor activity(GO:0042030)
1.9 5.7 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) steroid delta-isomerase activity(GO:0004769)
1.9 7.5 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
1.9 1.9 GO:0031432 titin binding(GO:0031432) RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
1.8 23.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
1.8 46.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.8 3.5 GO:0010465 nerve growth factor receptor activity(GO:0010465)
1.7 6.7 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
1.6 31.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
1.5 24.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
1.5 29.6 GO:0045295 gamma-catenin binding(GO:0045295)
1.5 30.7 GO:0035497 cAMP response element binding(GO:0035497)
1.4 5.8 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
1.4 36.5 GO:0030506 ankyrin binding(GO:0030506)
1.4 8.4 GO:0009378 four-way junction helicase activity(GO:0009378)
1.3 4.0 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
1.3 26.6 GO:0031005 filamin binding(GO:0031005)
1.3 14.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
1.2 96.1 GO:0008307 structural constituent of muscle(GO:0008307)
1.2 8.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
1.2 3.5 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
1.2 16.3 GO:0042043 neurexin family protein binding(GO:0042043)
1.1 9.9 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
1.1 3.3 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
1.1 3.3 GO:0042015 interleukin-20 binding(GO:0042015)
1.1 5.4 GO:0017018 myosin phosphatase activity(GO:0017018)
1.0 19.7 GO:0033130 acetylcholine receptor binding(GO:0033130) protein anchor(GO:0043495)
1.0 4.0 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
1.0 3.0 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
1.0 50.6 GO:0016504 peptidase activator activity(GO:0016504)
1.0 38.1 GO:0001972 retinoic acid binding(GO:0001972)
1.0 23.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.9 9.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.9 7.1 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.9 20.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.9 3.5 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.8 3.4 GO:0047708 biotinidase activity(GO:0047708)
0.8 15.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.8 2.5 GO:0015403 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.8 4.0 GO:0034046 poly(G) binding(GO:0034046)
0.8 72.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.7 5.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.7 5.7 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.7 7.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.7 4.6 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.6 2.6 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.6 10.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.6 5.0 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.6 5.6 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.6 3.6 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.6 7.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.5 6.0 GO:0008432 JUN kinase binding(GO:0008432)
0.5 5.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.5 2.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.5 32.4 GO:0017022 myosin binding(GO:0017022)
0.5 6.3 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.5 2.7 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.4 1.7 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.4 3.4 GO:0031014 troponin T binding(GO:0031014)
0.4 1.7 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.4 12.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.4 2.4 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.4 34.7 GO:0032947 protein complex scaffold(GO:0032947)
0.3 1.0 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.3 8.7 GO:0042169 SH2 domain binding(GO:0042169)
0.3 2.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.3 2.2 GO:0030332 cyclin binding(GO:0030332)
0.3 5.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.3 32.9 GO:0019838 growth factor binding(GO:0019838)
0.3 6.8 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.3 1.8 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3 3.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.3 34.4 GO:0051219 phosphoprotein binding(GO:0051219)
0.3 5.5 GO:0005537 mannose binding(GO:0005537)
0.3 3.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.3 5.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 3.0 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.3 4.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.3 0.5 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.3 2.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 2.0 GO:0031433 telethonin binding(GO:0031433)
0.2 36.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.2 10.7 GO:0005504 fatty acid binding(GO:0005504)
0.2 11.2 GO:0008009 chemokine activity(GO:0008009)
0.2 7.5 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.2 22.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 9.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 175.8 GO:0005509 calcium ion binding(GO:0005509)
0.2 12.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 0.9 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 5.0 GO:0070064 proline-rich region binding(GO:0070064)
0.2 4.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.2 5.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 11.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 2.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 12.4 GO:0019003 GDP binding(GO:0019003)
0.2 0.8 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 5.2 GO:0019894 kinesin binding(GO:0019894)
0.2 5.6 GO:0008013 beta-catenin binding(GO:0008013)
0.2 13.7 GO:0003777 microtubule motor activity(GO:0003777)
0.2 0.5 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.2 1.9 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 2.0 GO:0017166 vinculin binding(GO:0017166)
0.2 4.3 GO:0035173 histone kinase activity(GO:0035173)
0.2 2.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 1.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 12.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.7 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 2.8 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 41.8 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 6.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 31.0 GO:0003924 GTPase activity(GO:0003924)
0.1 3.6 GO:0030507 spectrin binding(GO:0030507)
0.1 17.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 13.7 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.1 3.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 11.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 3.3 GO:0030165 PDZ domain binding(GO:0030165)
0.1 4.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 1.2 GO:0005112 Notch binding(GO:0005112)
0.1 5.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 0.7 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.1 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.8 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.1 0.8 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 3.9 GO:0097110 scaffold protein binding(GO:0097110)
0.1 2.1 GO:0030515 snoRNA binding(GO:0030515)
0.1 13.7 GO:0008017 microtubule binding(GO:0008017)
0.1 4.8 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 2.5 GO:0043621 protein self-association(GO:0043621)
0.1 7.9 GO:0005179 hormone activity(GO:0005179)
0.1 1.1 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 1.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.2 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 2.1 GO:0005507 copper ion binding(GO:0005507)
0.1 2.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.3 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 2.8 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 10.4 GO:0005198 structural molecule activity(GO:0005198)
0.0 1.1 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 1.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.6 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.9 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 6.6 GO:0000287 magnesium ion binding(GO:0000287)
0.0 2.4 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.2 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 4.8 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.7 GO:0051087 chaperone binding(GO:0051087)
0.0 0.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 2.8 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 2.1 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 1.2 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.6 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 1.4 GO:0047485 protein N-terminus binding(GO:0047485)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 149.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
4.1 397.9 PID TGFBR PATHWAY TGF-beta receptor signaling
2.0 116.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
1.4 23.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
1.1 39.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
1.1 4.6 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.9 21.7 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.9 12.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.9 42.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.8 30.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.8 63.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.7 25.5 PID IL27 PATHWAY IL27-mediated signaling events
0.7 40.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.7 56.8 PID NOTCH PATHWAY Notch signaling pathway
0.6 9.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.6 115.6 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.6 26.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.6 6.8 PID NECTIN PATHWAY Nectin adhesion pathway
0.5 9.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.5 17.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.5 43.3 PID AP1 PATHWAY AP-1 transcription factor network
0.4 8.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.4 16.0 NABA COLLAGENS Genes encoding collagen proteins
0.4 11.4 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.4 18.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.3 8.0 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.3 4.3 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.3 49.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3 4.6 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.3 5.6 PID IL3 PATHWAY IL3-mediated signaling events
0.2 9.1 PID ARF6 PATHWAY Arf6 signaling events
0.2 7.8 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 5.1 PID ARF 3PATHWAY Arf1 pathway
0.2 13.3 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.2 4.0 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 7.5 PID FGF PATHWAY FGF signaling pathway
0.2 6.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.2 5.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.2 4.2 PID CDC42 PATHWAY CDC42 signaling events
0.2 4.0 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.2 5.5 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.2 31.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 1.1 ST GA12 PATHWAY G alpha 12 Pathway
0.2 7.1 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 1.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 0.6 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 0.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 17.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 1.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 2.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 15.0 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 2.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.7 PID P75 NTR PATHWAY p75(NTR)-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
7.0 265.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
6.9 124.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
5.7 362.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
4.1 119.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
3.5 38.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
2.5 61.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
2.3 64.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
2.3 55.0 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
1.5 31.9 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
1.3 32.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
1.3 23.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
1.3 37.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
1.2 22.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
1.0 26.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.9 23.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.8 20.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.7 10.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.7 25.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.7 17.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.5 26.6 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.5 5.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.5 11.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.5 7.4 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.5 6.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.4 15.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.4 5.7 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.4 44.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.4 9.9 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.3 8.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.3 4.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.3 8.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.3 7.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.3 32.6 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.3 8.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 6.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.3 16.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 10.7 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.2 13.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 6.1 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.2 11.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.2 2.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 3.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 15.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 9.7 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 4.9 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 0.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 5.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 2.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 1.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 4.3 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 6.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 2.9 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.1 1.2 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.1 9.1 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 5.2 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 2.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.4 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.1 0.9 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 2.1 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.0 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.5 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 1.7 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 3.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.3 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.8 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor