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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TFAP2B

Z-value: 1.16

Motif logo

Transcription factors associated with TFAP2B

Gene Symbol Gene ID Gene Info
ENSG00000008196.8 transcription factor AP-2 beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFAP2Bhg19_v2_chr6_+_50786414_507864390.336.3e-07Click!

Activity profile of TFAP2B motif

Sorted Z-values of TFAP2B motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_15114603 17.37 ENST00000228945.4
Rho GDP dissociation inhibitor (GDI) beta
chr11_+_1889880 16.72 ENST00000405957.2
lymphocyte-specific protein 1
chr12_-_15114492 14.49 ENST00000541546.1
Rho GDP dissociation inhibitor (GDI) beta
chr11_-_64512803 13.85 ENST00000377489.1
ENST00000354024.3
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr17_-_61777459 13.80 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIM domain containing 2
chr16_+_1583567 13.76 ENST00000566264.1
transmembrane protein 204
chr2_-_43453734 13.50 ENST00000282388.3
ZFP36 ring finger protein-like 2
chr11_-_64512273 13.23 ENST00000377497.3
ENST00000377487.1
ENST00000430645.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr4_-_84030996 11.91 ENST00000411416.2
placenta-specific 8
chr19_+_42724423 11.82 ENST00000301215.3
ENST00000597945.1
zinc finger protein 526
chr19_+_45971246 11.18 ENST00000585836.1
ENST00000417353.2
ENST00000353609.3
ENST00000591858.1
ENST00000443841.2
ENST00000590335.1
FBJ murine osteosarcoma viral oncogene homolog B
chr3_-_49459865 10.98 ENST00000427987.1
aminomethyltransferase
chr1_+_209929377 10.87 ENST00000400959.3
ENST00000367025.3
TRAF3 interacting protein 3
chr7_+_44143925 10.70 ENST00000223357.3
AE binding protein 1
chr7_+_94023873 10.68 ENST00000297268.6
collagen, type I, alpha 2
chr19_+_1067492 10.66 ENST00000586866.1
histocompatibility (minor) HA-1
chr7_-_150498426 10.63 ENST00000447204.2
transmembrane protein 176B
chr19_+_1067144 10.63 ENST00000313093.2
histocompatibility (minor) HA-1
chr3_-_49459878 10.39 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
aminomethyltransferase
chr19_+_1067271 10.30 ENST00000536472.1
ENST00000590214.1
histocompatibility (minor) HA-1
chr14_+_92980111 10.02 ENST00000216487.7
ENST00000557762.1
Ras and Rab interactor 3
chr8_+_22462532 10.01 ENST00000389279.3
cell cycle and apoptosis regulator 2
chr19_-_19739007 9.76 ENST00000586703.1
ENST00000591042.1
ENST00000407877.3
lysophosphatidic acid receptor 2
chr12_+_7060432 9.58 ENST00000318974.9
ENST00000456013.1
protein tyrosine phosphatase, non-receptor type 6
chr11_-_64512469 9.46 ENST00000377485.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr19_-_18717627 9.42 ENST00000392386.3
cytokine receptor-like factor 1
chr1_+_209929494 9.29 ENST00000367026.3
TRAF3 interacting protein 3
chr11_-_417388 9.25 ENST00000332725.3
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr7_+_150498783 9.19 ENST00000475536.1
ENST00000468689.1
transmembrane protein 176A
chr7_+_150498610 9.08 ENST00000461345.1
transmembrane protein 176A
chr11_+_809961 8.97 ENST00000530797.1
ribosomal protein, large, P2
chr5_-_150603679 8.96 ENST00000355417.2
coiled-coil domain containing 69
chr1_-_25291475 8.92 ENST00000338888.3
ENST00000399916.1
runt-related transcription factor 3
chr8_+_22462145 8.82 ENST00000308511.4
ENST00000523801.1
ENST00000521301.1
cell cycle and apoptosis regulator 2
chr1_+_32716840 8.81 ENST00000336890.5
lymphocyte-specific protein tyrosine kinase
chr11_-_66084508 8.80 ENST00000311330.3
CD248 molecule, endosialin
chr11_+_809647 8.43 ENST00000321153.4
ribosomal protein, large, P2
chr17_+_42429493 8.40 ENST00000586242.1
granulin
chr2_+_45878790 8.14 ENST00000306156.3
protein kinase C, epsilon
chr3_+_42544084 8.00 ENST00000543411.1
ENST00000438259.2
ENST00000439731.1
ENST00000325123.4
vasoactive intestinal peptide receptor 1
chr11_-_6677018 7.98 ENST00000299441.3
dachsous cadherin-related 1
chr11_-_64511789 7.82 ENST00000419843.1
ENST00000394430.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr2_+_85922491 7.02 ENST00000526018.1
granulysin
chr19_+_41107249 6.98 ENST00000396819.3
latent transforming growth factor beta binding protein 4
chr16_+_30960375 6.95 ENST00000318663.4
ENST00000566237.1
ENST00000562699.1
ORAI calcium release-activated calcium modulator 3
chr1_+_32716857 6.89 ENST00000482949.1
ENST00000495610.2
lymphocyte-specific protein tyrosine kinase
chr8_+_142402089 6.89 ENST00000521578.1
ENST00000520105.1
ENST00000523147.1
protein tyrosine phosphatase type IVA, member 3
chr11_+_810221 6.68 ENST00000530398.1
ribosomal protein, large, P2
chr22_-_51017084 6.66 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
carnitine palmitoyltransferase 1B (muscle)
chr10_-_99393208 6.39 ENST00000307450.6
MORN repeat containing 4
chr19_-_11689752 6.36 ENST00000592659.1
ENST00000592828.1
ENST00000218758.5
ENST00000412435.2
acid phosphatase 5, tartrate resistant
chr19_+_55897297 6.36 ENST00000431533.2
ENST00000428193.2
ENST00000558815.1
ENST00000560583.1
ENST00000560055.1
ENST00000559463.1
ribosomal protein L28
chr19_-_10450287 6.32 ENST00000589261.1
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
intercellular adhesion molecule 3
chr1_+_27719148 6.20 ENST00000374024.3
G protein-coupled receptor 3
chr11_+_2466218 6.19 ENST00000155840.5
potassium voltage-gated channel, KQT-like subfamily, member 1
chrX_-_1572629 6.19 ENST00000534940.1
acetylserotonin O-methyltransferase-like
chr19_+_7701985 6.11 ENST00000595950.1
ENST00000441779.2
ENST00000221283.5
ENST00000414284.2
syntaxin binding protein 2
chr22_+_31892373 6.04 ENST00000443011.1
ENST00000400289.1
ENST00000444859.1
ENST00000400288.2
Sfi1 homolog, spindle assembly associated (yeast)
chr12_-_89746173 6.03 ENST00000308385.6
dual specificity phosphatase 6
chr19_-_10450328 5.90 ENST00000160262.5
intercellular adhesion molecule 3
chr19_+_7710774 5.90 ENST00000602355.1
syntaxin binding protein 2
chr19_+_10828795 5.83 ENST00000389253.4
ENST00000355667.6
ENST00000408974.4
dynamin 2
chr5_+_177540444 5.75 ENST00000274605.5
NEDD4 binding protein 3
chr22_-_31742218 5.73 ENST00000266269.5
ENST00000405309.3
ENST00000351933.4
POZ (BTB) and AT hook containing zinc finger 1
chr22_-_39639021 5.64 ENST00000455790.1
platelet-derived growth factor beta polypeptide
chr10_-_99393242 5.63 ENST00000370635.3
ENST00000478953.1
ENST00000335628.3
MORN repeat containing 4
chr19_+_5623186 5.51 ENST00000538656.1
scaffold attachment factor B
chr19_-_19774473 5.49 ENST00000357324.6
ATPase type 13A1
chr10_+_99079008 5.32 ENST00000371021.3
frequently rearranged in advanced T-cell lymphomas
chr19_+_50706866 5.28 ENST00000440075.2
ENST00000376970.2
ENST00000425460.1
ENST00000599920.1
ENST00000601313.1
myosin, heavy chain 14, non-muscle
chr2_-_87018784 5.25 ENST00000283635.3
ENST00000538832.1
CD8a molecule
chr8_+_142138799 5.24 ENST00000518668.1
DENN/MADD domain containing 3
chr13_-_111567353 5.20 ENST00000310847.4
ENST00000267339.2
ENST00000375758.5
ankyrin repeat domain 10
chr19_+_10828724 5.00 ENST00000585892.1
ENST00000314646.5
ENST00000359692.6
dynamin 2
chr17_+_4613918 5.00 ENST00000574954.1
ENST00000346341.2
ENST00000572457.1
ENST00000381488.6
ENST00000412477.3
ENST00000571428.1
ENST00000575877.1
arrestin, beta 2
chr17_-_5138099 4.98 ENST00000571800.1
ENST00000574081.1
ENST00000399600.4
ENST00000574297.1
SLP adaptor and CSK interacting membrane protein
chr14_+_23340822 4.88 ENST00000359591.4
low density lipoprotein receptor-related protein 10
chr8_+_142138711 4.86 ENST00000518347.1
ENST00000262585.2
ENST00000424248.1
ENST00000519811.1
ENST00000520986.1
ENST00000523058.1
DENN/MADD domain containing 3
chr19_-_55866061 4.85 ENST00000588572.2
ENST00000593184.1
ENST00000589467.1
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr5_-_79287060 4.85 ENST00000512560.1
ENST00000509852.1
ENST00000512528.1
metaxin 3
chr17_+_18163848 4.84 ENST00000323019.4
ENST00000578174.1
ENST00000395704.4
ENST00000395703.4
ENST00000578621.1
ENST00000579341.1
mitochondrial elongation factor 2
chr17_-_8093471 4.82 ENST00000389017.4
chromosome 17 open reading frame 59
chr15_-_35047166 4.79 ENST00000290374.4
gap junction protein, delta 2, 36kDa
chr10_+_11047259 4.76 ENST00000379261.4
ENST00000416382.2
CUGBP, Elav-like family member 2
chr19_+_42746927 4.67 ENST00000378108.1
AC006486.1
chr10_+_76585303 4.63 ENST00000372725.1
K(lysine) acetyltransferase 6B
chr9_+_124030338 4.55 ENST00000449773.1
ENST00000432226.1
ENST00000436847.1
ENST00000394353.2
ENST00000449733.1
ENST00000412819.1
ENST00000341272.2
ENST00000373808.2
gelsolin
chr19_+_5623083 4.51 ENST00000292123.5
ENST00000592224.1
ENST00000454510.1
ENST00000433404.1
ENST00000588852.1
scaffold attachment factor B
chr4_+_78078304 4.46 ENST00000316355.5
ENST00000354403.5
ENST00000502280.1
cyclin G2
chr19_+_42387228 4.44 ENST00000354532.3
ENST00000599846.1
ENST00000347545.4
Rho guanine nucleotide exchange factor (GEF) 1
chr21_+_45719921 4.43 ENST00000349048.4
phosphofructokinase, liver
chr8_-_21988558 4.36 ENST00000312841.8
hair growth associated
chr16_-_75498308 4.35 ENST00000569540.1
transmembrane protein 170A
chr16_+_67465016 4.29 ENST00000326152.5
hydroxysteroid (11-beta) dehydrogenase 2
chr16_-_67970990 4.26 ENST00000358514.4
proteasome (prosome, macropain) subunit, beta type, 10
chr5_-_176981417 4.23 ENST00000514747.1
ENST00000443375.2
ENST00000329540.5
family with sequence similarity 193, member B
chr8_-_70983506 4.21 ENST00000276594.2
PR domain containing 14
chr11_+_8704298 4.19 ENST00000531978.1
ENST00000524496.1
ENST00000532359.1
ENST00000530022.1
ribosomal protein L27a
chr12_-_89919965 4.17 ENST00000548729.1
POC1B-GALNT4 readthrough
chr14_+_65171099 4.16 ENST00000247226.7
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr19_+_55897699 4.13 ENST00000558131.1
ENST00000558752.1
ENST00000458349.2
ribosomal protein L28
chr10_-_35930219 4.09 ENST00000374694.1
frizzled family receptor 8
chr5_-_157002749 4.09 ENST00000517905.1
ENST00000430702.2
ENST00000394020.1
ADAM metallopeptidase domain 19
chr15_+_78730531 4.02 ENST00000258886.8
iron-responsive element binding protein 2
chr19_+_36195429 4.01 ENST00000392197.2
zinc finger and BTB domain containing 32
chr19_+_7459998 4.00 ENST00000319670.9
ENST00000599752.1
Rho/Rac guanine nucleotide exchange factor (GEF) 18
chr3_-_169899504 3.99 ENST00000474275.1
ENST00000484931.1
ENST00000494943.1
ENST00000497658.1
ENST00000465896.1
ENST00000475729.1
ENST00000495893.2
ENST00000481639.1
ENST00000467570.1
ENST00000466189.1
polyhomeotic homolog 3 (Drosophila)
chr14_-_92413353 3.94 ENST00000556154.1
fibulin 5
chr19_+_35645618 3.93 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD domain containing ion transport regulator 5
chr16_+_89627061 3.90 ENST00000311528.5
ENST00000563270.1
ENST00000567815.1
ENST00000452368.3
ENST00000467736.1
ENST00000393099.3
ribosomal protein L13
chr8_+_123793633 3.89 ENST00000314393.4
zinc fingers and homeoboxes 2
chr13_+_28712614 3.89 ENST00000380958.3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr21_+_44394620 3.88 ENST00000291547.5
PBX/knotted 1 homeobox 1
chr16_+_22825475 3.85 ENST00000261374.3
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr5_-_174871136 3.78 ENST00000393752.2
dopamine receptor D1
chr19_+_14544099 3.77 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
protein kinase N1
chr1_+_153746683 3.76 ENST00000271857.2
solute carrier family 27 (fatty acid transporter), member 3
chrX_-_78622805 3.68 ENST00000373298.2
integral membrane protein 2A
chr15_-_44955842 3.68 ENST00000427534.2
ENST00000559193.1
ENST00000261866.7
ENST00000535302.2
ENST00000558319.1
spastic paraplegia 11 (autosomal recessive)
chr19_+_19144384 3.67 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
armadillo repeat containing 6
chr16_+_28835437 3.64 ENST00000568266.1
ataxin 2-like
chr3_+_10857885 3.61 ENST00000254488.2
ENST00000454147.1
solute carrier family 6 (neurotransmitter transporter), member 11
chr10_-_99094458 3.60 ENST00000371019.2
frequently rearranged in advanced T-cell lymphomas 2
chrX_+_9983602 3.59 ENST00000380861.4
WWC family member 3
chr5_+_149737202 3.53 ENST00000451292.1
ENST00000377797.3
ENST00000445265.2
ENST00000323668.7
ENST00000439160.2
ENST00000394269.3
ENST00000427724.2
ENST00000504761.2
ENST00000513346.1
ENST00000515516.1
Treacher Collins-Franceschetti syndrome 1
chr10_+_104178946 3.51 ENST00000432590.1
F-box and leucine-rich repeat protein 15
chr16_-_20556492 3.50 ENST00000568098.1
acyl-CoA synthetase medium-chain family member 2B
chr2_+_120770581 3.50 ENST00000263713.5
erythrocyte membrane protein band 4.1 like 5
chr3_-_48470838 3.50 ENST00000358459.4
ENST00000358536.4
plexin B1
chr19_-_55866104 3.49 ENST00000326529.4
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr11_-_62379994 3.47 ENST00000278845.4
ENST00000529309.1
echinoderm microtubule associated protein like 3
chr19_+_17858547 3.47 ENST00000600676.1
ENST00000600209.1
ENST00000596309.1
ENST00000598539.1
ENST00000597474.1
ENST00000593385.1
ENST00000598067.1
ENST00000593833.1
FCH domain only 1
chr6_+_35227449 3.45 ENST00000373953.3
ENST00000440666.2
ENST00000339411.5
zinc finger protein 76
chr21_+_44394742 3.41 ENST00000432907.2
PBX/knotted 1 homeobox 1
chrX_+_131157290 3.40 ENST00000394334.2
Serine/threonine-protein kinase MST4
chr22_-_27620603 3.39 ENST00000418271.1
ENST00000444114.1
RP5-1172A22.1
chr8_+_56792355 3.39 ENST00000519728.1
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr19_-_42746714 3.37 ENST00000222330.3
glycogen synthase kinase 3 alpha
chr8_+_38758737 3.35 ENST00000521746.1
ENST00000420274.1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr17_-_39942940 3.34 ENST00000310706.5
ENST00000393931.3
ENST00000424457.1
ENST00000591690.1
junction plakoglobin
chr6_-_34664612 3.32 ENST00000374023.3
ENST00000374026.3
chromosome 6 open reading frame 106
chr19_+_39833036 3.32 ENST00000602243.1
ENST00000598913.1
ENST00000314471.6
sterile alpha motif domain containing 4B
chr11_+_120382417 3.31 ENST00000527524.2
ENST00000375081.2
glutamate receptor, ionotropic, kainate 4
Uncharacterized protein
chr3_+_23958632 3.29 ENST00000412097.1
ENST00000415719.1
ENST00000435882.1
ribosomal protein L15
chr17_-_61777090 3.27 ENST00000578061.1
LIM domain containing 2
chr1_-_15911510 3.26 ENST00000375826.3
agmatine ureohydrolase (agmatinase)
chr17_-_73257667 3.26 ENST00000538886.1
ENST00000580799.1
ENST00000351904.7
ENST00000537686.1
golgi-associated, gamma adaptin ear containing, ARF binding protein 3
chr10_+_124134201 3.26 ENST00000368990.3
ENST00000368988.1
ENST00000368989.2
ENST00000463663.2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr1_+_100818156 3.25 ENST00000336454.3
cell division cycle 14A
chr12_+_93772402 3.24 ENST00000546925.1
nudix (nucleoside diphosphate linked moiety X)-type motif 4
chr1_-_49242553 3.23 ENST00000371833.3
BEN domain containing 5
chr1_+_158969752 3.22 ENST00000566111.1
interferon, gamma-inducible protein 16
chr13_+_20532807 3.20 ENST00000382869.3
ENST00000382881.3
zinc finger, MYM-type 2
chr19_-_10679644 3.17 ENST00000393599.2
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr11_-_47399942 3.16 ENST00000227163.4
spleen focus forming virus (SFFV) proviral integration oncogene
chr11_-_62380199 3.14 ENST00000419857.1
ENST00000394773.2
echinoderm microtubule associated protein like 3
chr17_-_79869004 3.13 ENST00000573927.1
ENST00000331285.3
ENST00000572157.1
phosphate cytidylyltransferase 2, ethanolamine
chr7_+_150549565 3.13 ENST00000360937.4
ENST00000416793.2
ENST00000483043.1
amine oxidase, copper containing 1
chrX_+_131157322 3.11 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
Serine/threonine-protein kinase MST4
chr19_+_37341260 3.10 ENST00000589046.1
zinc finger protein 345
chr16_+_23847339 3.08 ENST00000303531.7
protein kinase C, beta
chr11_-_47400078 3.08 ENST00000378538.3
spleen focus forming virus (SFFV) proviral integration oncogene
chr7_-_143105941 3.08 ENST00000275815.3
EPH receptor A1
chr3_-_158450475 3.07 ENST00000237696.5
retinoic acid receptor responder (tazarotene induced) 1
chr5_+_156693159 3.06 ENST00000347377.6
cytoplasmic FMR1 interacting protein 2
chr15_+_78730622 3.02 ENST00000560440.1
iron-responsive element binding protein 2
chr11_+_24518723 3.02 ENST00000336930.6
ENST00000529015.1
ENST00000533227.1
leucine zipper protein 2
chr11_+_8040739 3.02 ENST00000534099.1
tubby bipartite transcription factor
chr7_-_86849883 3.01 ENST00000433078.1
transmembrane protein 243, mitochondrial
chr17_-_5487768 2.98 ENST00000269280.4
ENST00000345221.3
ENST00000262467.5
NLR family, pyrin domain containing 1
chr5_+_149569520 2.95 ENST00000230671.2
ENST00000524041.1
solute carrier family 6 (neurotransmitter transporter), member 7
chr17_-_6554877 2.95 ENST00000225728.3
ENST00000575197.1
mediator complex subunit 31
chr16_+_19179549 2.92 ENST00000355377.2
ENST00000568115.1
synaptotagmin XVII
chr22_-_36018569 2.90 ENST00000419229.1
ENST00000406324.1
myoglobin
chr8_+_56792377 2.88 ENST00000520220.2
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr1_+_29213678 2.88 ENST00000347529.3
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr1_+_100818009 2.82 ENST00000370125.2
ENST00000361544.6
ENST00000370124.3
cell division cycle 14A
chr15_+_85144217 2.82 ENST00000540936.1
ENST00000448803.2
ENST00000546275.1
ENST00000546148.1
ENST00000442073.3
ENST00000334141.3
ENST00000358472.3
ENST00000502939.2
ENST00000379358.3
ENST00000327179.6
zinc finger and SCAN domain containing 2
chr21_-_45078019 2.79 ENST00000542962.1
heat shock transcription factor 2 binding protein
chr19_-_41859814 2.79 ENST00000221930.5
transforming growth factor, beta 1
chrX_-_17879356 2.78 ENST00000331511.1
ENST00000415486.3
ENST00000545871.1
ENST00000451717.1
retinoic acid induced 2
chr16_-_2827128 2.77 ENST00000494946.2
ENST00000409477.1
ENST00000572954.1
ENST00000262306.7
ENST00000409906.4
transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
chr4_-_2010562 2.74 ENST00000411649.1
ENST00000542778.1
ENST00000411638.2
ENST00000431323.1
negative elongation factor complex member A
chr20_-_35724388 2.73 ENST00000344359.3
ENST00000373664.3
retinoblastoma-like 1 (p107)
chr12_+_31477250 2.73 ENST00000313737.4
AC024940.1
chr13_+_60971427 2.71 ENST00000535286.1
ENST00000377881.2
tudor domain containing 3
chr11_+_63606558 2.68 ENST00000350490.7
ENST00000502399.3
MAP/microtubule affinity-regulating kinase 2
chr13_-_20437772 2.67 ENST00000337963.4
zinc finger, MYM-type 5
chr5_-_157002775 2.66 ENST00000257527.4
ADAM metallopeptidase domain 19
chr14_-_24551137 2.65 ENST00000396995.1
neural retina leucine zipper
chr6_-_35464817 2.65 ENST00000338863.7
TEA domain family member 3
chr20_-_50808236 2.64 ENST00000361387.2
ZFP64 zinc finger protein
chr19_+_36195467 2.62 ENST00000426659.2
zinc finger and BTB domain containing 32
chr4_+_71570430 2.62 ENST00000417478.2
RUN and FYVE domain containing 3
chrX_-_83442915 2.61 ENST00000262752.2
ENST00000543399.1
ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr1_+_221054584 2.61 ENST00000549319.1
H2.0-like homeobox
chr8_-_59572093 2.60 ENST00000427130.2
neutral sphingomyelinase (N-SMase) activation associated factor
chr6_-_35464727 2.59 ENST00000402886.3
TEA domain family member 3
chr2_-_208030647 2.57 ENST00000309446.6
Kruppel-like factor 7 (ubiquitous)
chr7_-_92157760 2.57 ENST00000248633.4
peroxisomal biogenesis factor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP2B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
8.0 31.9 GO:0071461 cellular response to redox state(GO:0071461)
4.3 21.4 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
3.6 10.8 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
2.9 11.8 GO:0044027 hypermethylation of CpG island(GO:0044027)
2.7 8.0 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
2.4 9.6 GO:0033277 abortive mitotic cell cycle(GO:0033277)
2.4 9.4 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
2.3 7.0 GO:0002818 intracellular defense response(GO:0002818)
2.1 6.3 GO:0070666 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
2.1 6.2 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
2.1 28.9 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
2.0 6.0 GO:0003383 apical constriction(GO:0003383) mesoderm migration involved in gastrulation(GO:0007509)
1.9 13.5 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
1.7 5.1 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
1.5 6.0 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
1.4 5.6 GO:1905174 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
1.4 4.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
1.4 4.1 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
1.3 18.8 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
1.3 5.3 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
1.3 9.2 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
1.3 5.3 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
1.3 6.4 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
1.2 3.7 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
1.1 6.9 GO:0043117 positive regulation of vascular permeability(GO:0043117)
1.1 4.5 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
1.0 5.0 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
1.0 15.7 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
1.0 2.9 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.9 2.8 GO:0046732 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.9 3.7 GO:0002317 plasma cell differentiation(GO:0002317)
0.9 3.7 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.9 4.6 GO:0032455 nerve growth factor processing(GO:0032455)
0.9 6.4 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.9 4.5 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.9 5.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.9 2.6 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.8 3.3 GO:0002159 desmosome assembly(GO:0002159)
0.8 3.3 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.8 8.1 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.8 2.4 GO:0003335 corneocyte development(GO:0003335)
0.8 13.3 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.8 14.8 GO:0051255 spindle midzone assembly(GO:0051255)
0.8 2.3 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.8 6.2 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.8 2.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.8 3.8 GO:0035106 operant conditioning(GO:0035106)
0.7 11.9 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.7 2.2 GO:0006014 D-ribose metabolic process(GO:0006014)
0.7 3.5 GO:0072313 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.7 1.4 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.7 7.0 GO:0002115 store-operated calcium entry(GO:0002115)
0.7 10.3 GO:0043589 skin morphogenesis(GO:0043589)
0.6 6.5 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.6 2.5 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.6 1.3 GO:0002384 hepatic immune response(GO:0002384)
0.6 3.8 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.6 1.8 GO:0003072 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.6 1.8 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.6 1.8 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.6 2.9 GO:0035524 proline transmembrane transport(GO:0035524)
0.6 2.3 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.6 11.7 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.6 1.7 GO:0010193 response to ozone(GO:0010193)
0.6 1.7 GO:0035283 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.6 5.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.6 1.7 GO:0045659 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.6 3.9 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.6 1.7 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.5 1.6 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.5 48.4 GO:0071277 cellular response to calcium ion(GO:0071277)
0.5 3.1 GO:0071504 response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
0.5 2.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.5 3.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.5 1.8 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.5 1.8 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.5 13.8 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.4 4.0 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.4 2.6 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.4 1.7 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.4 2.6 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.4 1.3 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.4 0.4 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.4 0.8 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.4 3.7 GO:0042278 purine nucleoside metabolic process(GO:0042278)
0.4 2.4 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.4 1.2 GO:0006524 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080)
0.4 3.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.4 5.2 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.4 7.3 GO:0006853 carnitine shuttle(GO:0006853)
0.4 2.9 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.4 2.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.4 1.8 GO:0090625 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.3 4.5 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.3 1.4 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.3 1.0 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.3 36.4 GO:0002181 cytoplasmic translation(GO:0002181)
0.3 1.7 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.3 1.3 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.3 8.9 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.3 3.9 GO:0048251 elastic fiber assembly(GO:0048251)
0.3 9.8 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.3 2.6 GO:0060751 branch elongation involved in mammary gland duct branching(GO:0060751)
0.3 3.2 GO:0048102 autophagic cell death(GO:0048102)
0.3 1.3 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.3 4.4 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.3 1.9 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.3 3.0 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to photoreceptor outer segment(GO:1903546)
0.3 12.0 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.3 2.1 GO:0015816 glycine transport(GO:0015816)
0.3 3.5 GO:0014029 neural crest formation(GO:0014029)
0.3 1.2 GO:0060996 dendritic spine development(GO:0060996)
0.3 4.8 GO:0008053 mitochondrial fusion(GO:0008053)
0.3 0.8 GO:0006145 purine nucleobase catabolic process(GO:0006145) beta-alanine metabolic process(GO:0019482)
0.3 1.4 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.3 0.8 GO:0035634 response to stilbenoid(GO:0035634)
0.3 0.8 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) primary lung bud formation(GO:0060431) lung induction(GO:0060492)
0.3 1.1 GO:0002266 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.3 1.3 GO:1904693 midbrain morphogenesis(GO:1904693)
0.3 1.0 GO:0042414 epinephrine metabolic process(GO:0042414) epinephrine biosynthetic process(GO:0042418)
0.3 2.6 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.3 5.6 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.3 1.8 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.3 0.8 GO:0061760 antifungal innate immune response(GO:0061760)
0.2 7.0 GO:0030252 growth hormone secretion(GO:0030252)
0.2 2.5 GO:0051552 flavone metabolic process(GO:0051552)
0.2 5.9 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.2 1.2 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.2 0.9 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.2 1.6 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 7.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.2 0.9 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.2 3.0 GO:0001553 luteinization(GO:0001553)
0.2 16.7 GO:0006968 cellular defense response(GO:0006968)
0.2 4.2 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 0.9 GO:0000189 MAPK import into nucleus(GO:0000189)
0.2 4.4 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.2 1.7 GO:0048484 enteric nervous system development(GO:0048484)
0.2 10.1 GO:0008333 endosome to lysosome transport(GO:0008333)
0.2 4.4 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.2 2.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.2 3.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.2 2.2 GO:0038203 TORC2 signaling(GO:0038203)
0.2 1.0 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.2 1.0 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.2 0.8 GO:0072299 visceral serous pericardium development(GO:0061032) posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) regulation of metanephric glomerular mesangial cell proliferation(GO:0072301) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.2 10.5 GO:1903146 regulation of mitophagy(GO:1903146)
0.2 1.0 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.2 1.1 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.2 3.6 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.2 0.6 GO:1905244 fasciculation of motor neuron axon(GO:0097156) regulation of modification of synaptic structure(GO:1905244)
0.2 0.7 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2 1.1 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) positive regulation of t-circle formation(GO:1904431)
0.2 2.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.2 1.3 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.2 3.6 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.2 3.5 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.2 2.1 GO:0015671 oxygen transport(GO:0015671)
0.1 7.4 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 0.6 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.1 1.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 2.0 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.1 0.8 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 4.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 2.5 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.1 9.2 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.1 0.4 GO:0072423 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.1 1.3 GO:0042416 dopamine biosynthetic process(GO:0042416)
0.1 3.5 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.1 3.3 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.3 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 2.6 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 1.7 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 2.9 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 2.2 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.1 5.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 7.0 GO:0006826 iron ion transport(GO:0006826)
0.1 6.2 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.1 1.5 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 3.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 1.4 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 1.4 GO:0032196 transposition(GO:0032196)
0.1 7.3 GO:0030218 erythrocyte differentiation(GO:0030218)
0.1 2.7 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.1 0.4 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703) multi-organism behavior(GO:0051705)
0.1 1.3 GO:0006449 regulation of translational termination(GO:0006449)
0.1 3.2 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 3.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 2.1 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.1 0.4 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 0.7 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 1.6 GO:0060070 canonical Wnt signaling pathway(GO:0060070)
0.1 7.8 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 1.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 1.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 1.5 GO:0071624 positive regulation of granulocyte chemotaxis(GO:0071624)
0.1 4.1 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)
0.1 6.0 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.1 1.6 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 4.6 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 2.7 GO:0051646 mitochondrion localization(GO:0051646)
0.1 0.6 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.1 0.7 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 4.4 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.1 1.7 GO:0038202 TORC1 signaling(GO:0038202)
0.1 2.7 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.1 7.6 GO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger(GO:0007187)
0.1 4.1 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.1 5.0 GO:0007127 meiosis I(GO:0007127)
0.1 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 3.9 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.1 3.3 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.1 1.1 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.1 1.8 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 0.5 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.9 GO:0008228 opsonization(GO:0008228)
0.0 0.9 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0 3.4 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 6.5 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.0 1.4 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.5 GO:0030239 myofibril assembly(GO:0030239)
0.0 1.2 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 1.6 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.4 GO:2000505 regulation of energy homeostasis(GO:2000505)
0.0 3.8 GO:0006023 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.0 1.5 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.5 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 1.3 GO:0042572 retinol metabolic process(GO:0042572)
0.0 1.1 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.9 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.6 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.0 0.1 GO:0043385 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.0 0.1 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.0 3.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 1.1 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 4.1 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.0 3.8 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 2.8 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 1.0 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.6 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 2.6 GO:0048839 inner ear development(GO:0048839)
0.0 3.4 GO:0016236 macroautophagy(GO:0016236)
0.0 1.6 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.2 GO:0030033 microvillus assembly(GO:0030033)
0.0 1.1 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 1.1 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.1 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 4.3 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)
0.0 0.1 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 4.1 GO:0007517 muscle organ development(GO:0007517)
0.0 0.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 1.1 GO:0046546 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 1.0 GO:0007586 digestion(GO:0007586)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
6.3 18.8 GO:0044609 DBIRD complex(GO:0044609)
3.1 9.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
2.1 19.0 GO:0044194 cytolytic granule(GO:0044194)
2.1 14.6 GO:0030061 mitochondrial crista(GO:0030061)
1.7 1.7 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
1.4 4.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
1.3 3.9 GO:0031251 PAN complex(GO:0031251)
1.2 3.5 GO:0005608 laminin-3 complex(GO:0005608)
1.1 5.3 GO:0097513 myosin II filament(GO:0097513)
0.9 10.7 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.9 4.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.9 9.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.8 5.8 GO:0060091 kinocilium(GO:0060091)
0.6 14.9 GO:0000242 pericentriolar material(GO:0000242)
0.6 2.9 GO:0070847 core mediator complex(GO:0070847)
0.6 4.0 GO:0035102 PRC1 complex(GO:0035102)
0.5 2.7 GO:0032021 NELF complex(GO:0032021)
0.5 10.8 GO:0001891 phagocytic cup(GO:0001891)
0.5 4.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.5 3.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.5 5.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.5 3.0 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.5 4.6 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.5 50.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.5 3.6 GO:0043196 varicosity(GO:0043196)
0.4 3.9 GO:0071953 elastic fiber(GO:0071953)
0.4 1.2 GO:1990909 Wnt signalosome(GO:1990909)
0.4 55.6 GO:0032587 ruffle membrane(GO:0032587)
0.3 1.3 GO:0016600 flotillin complex(GO:0016600)
0.3 1.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.3 4.5 GO:0030478 actin cap(GO:0030478)
0.3 4.5 GO:0031932 TORC2 complex(GO:0031932)
0.3 9.0 GO:0051233 spindle midzone(GO:0051233)
0.3 3.3 GO:0005915 zonula adherens(GO:0005915)
0.3 1.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.3 2.7 GO:0097427 microtubule bundle(GO:0097427)
0.3 2.9 GO:0002116 semaphorin receptor complex(GO:0002116)
0.3 3.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.3 2.3 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.3 5.3 GO:0042101 T cell receptor complex(GO:0042101)
0.2 5.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 2.6 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 0.9 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 4.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 1.8 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.2 1.0 GO:0070826 paraferritin complex(GO:0070826)
0.2 4.1 GO:0030131 clathrin adaptor complex(GO:0030131)
0.2 2.6 GO:0071437 invadopodium(GO:0071437)
0.2 1.8 GO:0005577 fibrinogen complex(GO:0005577)
0.2 1.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.1 0.9 GO:0061689 tricellular tight junction(GO:0061689)
0.1 5.1 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 20.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 1.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 2.6 GO:0031143 pseudopodium(GO:0031143)
0.1 13.5 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.0 GO:0097486 multivesicular body lumen(GO:0097486)
0.1 10.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 4.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 2.3 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 1.0 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 9.3 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 5.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 10.2 GO:0016605 PML body(GO:0016605)
0.1 6.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 1.9 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 6.7 GO:0005814 centriole(GO:0005814)
0.1 3.8 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.4 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 1.8 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.1 6.1 GO:0001650 fibrillar center(GO:0001650)
0.1 1.0 GO:0070069 endoplasmic reticulum chaperone complex(GO:0034663) cytochrome complex(GO:0070069)
0.1 1.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 1.1 GO:0031082 BLOC complex(GO:0031082)
0.0 0.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.6 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 1.4 GO:0002102 podosome(GO:0002102)
0.0 0.5 GO:0055037 recycling endosome(GO:0055037)
0.0 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 2.0 GO:0030018 Z disc(GO:0030018)
0.0 1.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 3.6 GO:0097708 cytoplasmic vesicle(GO:0031410) intracellular vesicle(GO:0097708)
0.0 3.2 GO:0016324 apical plasma membrane(GO:0016324)
0.0 3.7 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 3.0 GO:0060170 ciliary membrane(GO:0060170)
0.0 13.0 GO:0000790 nuclear chromatin(GO:0000790)
0.0 10.9 GO:0005769 early endosome(GO:0005769)
0.0 17.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 2.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.3 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.2 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.6 GO:0032420 stereocilium(GO:0032420)
0.0 1.6 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 3.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.3 GO:0001533 cornified envelope(GO:0001533)
0.0 1.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 3.4 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 3.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.6 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 5.3 GO:0043235 receptor complex(GO:0043235)
0.0 0.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.7 GO:0030426 growth cone(GO:0030426)
0.0 1.9 GO:0030496 midbody(GO:0030496)
0.0 69.7 GO:0016021 integral component of membrane(GO:0016021)
0.0 4.1 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 21.4 GO:0004047 aminomethyltransferase activity(GO:0004047)
3.2 31.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
2.6 15.7 GO:0042610 CD8 receptor binding(GO:0042610)
2.5 44.4 GO:0019992 diacylglycerol binding(GO:0019992)
2.4 12.0 GO:0030348 syntaxin-3 binding(GO:0030348)
2.3 7.0 GO:0030350 iron-responsive element binding(GO:0030350)
2.3 11.7 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
2.0 8.1 GO:0035276 ethanol binding(GO:0035276)
1.9 9.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
1.7 5.0 GO:0031859 platelet activating factor receptor binding(GO:0031859)
1.6 8.0 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
1.4 4.3 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
1.4 4.2 GO:0015039 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
1.4 4.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
1.3 6.7 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
1.3 6.6 GO:0070095 fructose-6-phosphate binding(GO:0070095)
1.2 16.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
1.1 9.8 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
1.1 10.8 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
1.0 6.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.9 3.8 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.9 2.8 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.9 6.3 GO:0043208 glycosphingolipid binding(GO:0043208)
0.8 13.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.8 3.2 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.8 8.4 GO:0051525 NFAT protein binding(GO:0051525)
0.7 2.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.7 10.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.7 1.3 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.6 2.6 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.6 6.5 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.6 3.8 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.6 1.3 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.6 3.8 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.6 4.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.6 3.6 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.6 1.8 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.6 2.9 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.6 2.3 GO:0016841 ammonia-lyase activity(GO:0016841)
0.6 5.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.6 1.7 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.5 7.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.5 1.6 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.5 6.9 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.5 6.4 GO:0008199 ferric iron binding(GO:0008199)
0.5 6.0 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.5 13.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.4 5.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.4 1.3 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
0.4 1.3 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.4 2.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.4 2.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.4 1.6 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.4 1.6 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.4 3.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.4 3.5 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.4 5.0 GO:0005344 oxygen transporter activity(GO:0005344)
0.4 4.5 GO:0045159 myosin II binding(GO:0045159)
0.4 20.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.4 3.3 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.4 3.7 GO:0045545 syndecan binding(GO:0045545)
0.4 3.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.4 1.8 GO:0051373 FATZ binding(GO:0051373)
0.3 1.0 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.3 5.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.3 1.4 GO:0004803 transposase activity(GO:0004803)
0.3 9.1 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.3 2.6 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.3 3.5 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.3 10.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.3 4.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.3 0.8 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.3 6.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.3 6.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.3 3.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.3 9.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.3 1.9 GO:0001515 opioid peptide activity(GO:0001515)
0.3 5.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.3 3.9 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.3 6.0 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.2 4.9 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.2 4.0 GO:0008494 translation activator activity(GO:0008494)
0.2 5.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 4.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 1.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2 2.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 1.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 0.9 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.2 2.4 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.2 3.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 20.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 0.6 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.2 0.8 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.2 2.5 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 3.5 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.2 0.7 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.2 3.6 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 1.8 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.2 36.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 3.3 GO:0030371 translation repressor activity(GO:0030371)
0.2 3.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 5.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.2 1.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 1.5 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 1.8 GO:0035198 miRNA binding(GO:0035198)
0.1 0.6 GO:0080084 RNA polymerase III transcription factor binding(GO:0001025) RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) 5S rDNA binding(GO:0080084)
0.1 0.9 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 4.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.8 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.7 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.6 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 4.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 1.0 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 7.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.9 GO:0004969 histamine receptor activity(GO:0004969)
0.1 1.7 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 1.8 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.8 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 2.2 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 1.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.4 GO:0036033 mediator complex binding(GO:0036033)
0.1 2.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 2.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 1.8 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 3.8 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1 6.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 2.7 GO:0001972 retinoic acid binding(GO:0001972)
0.1 4.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 1.3 GO:0004707 MAP kinase activity(GO:0004707)
0.1 8.8 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 0.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 2.0 GO:0005109 frizzled binding(GO:0005109)
0.1 0.9 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 1.0 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 1.4 GO:0002162 dystroglycan binding(GO:0002162)
0.1 1.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 2.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 6.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.2 GO:0008483 transaminase activity(GO:0008483)
0.1 1.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 1.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 1.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 1.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 1.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0017057 glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057)
0.0 7.3 GO:0001047 core promoter binding(GO:0001047)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 2.5 GO:0019213 deacetylase activity(GO:0019213)
0.0 5.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 4.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 2.5 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 1.6 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.9 GO:0005123 death receptor binding(GO:0005123)
0.0 0.4 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 1.4 GO:0008083 growth factor activity(GO:0008083)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.8 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 4.5 GO:0005125 cytokine activity(GO:0005125)
0.0 1.5 GO:0042379 chemokine receptor binding(GO:0042379)
0.0 9.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 2.6 GO:0005254 chloride channel activity(GO:0005254)
0.0 3.6 GO:0003823 antigen binding(GO:0003823)
0.0 1.7 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 8.4 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.6 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 4.5 GO:0003682 chromatin binding(GO:0003682)
0.0 1.8 GO:0002020 protease binding(GO:0002020)
0.0 0.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 2.6 GO:0001012 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.5 GO:0042623 ATPase activity, coupled(GO:0042623)
0.0 1.4 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 16.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
1.0 49.4 PID RAS PATHWAY Regulation of Ras family activation
0.5 21.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.5 40.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.4 6.3 PID IL5 PATHWAY IL5-mediated signaling events
0.4 3.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.3 29.6 PID IL4 2PATHWAY IL4-mediated signaling events
0.3 6.5 PID S1P S1P1 PATHWAY S1P1 pathway
0.3 14.6 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.3 8.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.2 12.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 4.5 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.2 3.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.2 6.5 PID LKB1 PATHWAY LKB1 signaling events
0.2 4.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 10.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 9.8 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.2 3.0 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 8.9 PID PI3KCI PATHWAY Class I PI3K signaling events
0.2 4.1 PID CD40 PATHWAY CD40/CD40L signaling
0.1 4.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 5.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 5.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 1.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 9.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 2.6 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 3.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 1.8 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 3.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 5.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 4.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 3.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 6.5 PID AP1 PATHWAY AP-1 transcription factor network
0.1 7.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 0.9 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 0.7 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.0 PID FOXO PATHWAY FoxO family signaling
0.1 2.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 1.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.4 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 2.6 PID TNF PATHWAY TNF receptor signaling pathway
0.1 1.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 1.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 4.8 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 3.7 PID BMP PATHWAY BMP receptor signaling
0.1 13.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 1.6 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 1.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 2.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 2.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 3.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 6.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID ATM PATHWAY ATM pathway
0.0 0.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.6 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.8 PID P73PATHWAY p73 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 31.6 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
1.2 51.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.9 10.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.8 5.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.6 11.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.6 10.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.6 7.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.4 71.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.4 8.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.4 4.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.4 6.0 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.3 4.4 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.3 8.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.3 50.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.3 9.7 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.3 5.9 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.3 1.8 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 8.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 10.1 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.2 21.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 5.8 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.2 9.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.2 3.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 3.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.2 3.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 6.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 2.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.2 4.1 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2 7.0 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 5.3 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.1 3.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 4.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 4.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 3.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 3.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 1.3 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 2.6 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 11.4 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.1 1.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 2.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 2.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 4.6 REACTOME SIGNALLING BY NGF Genes involved in Signalling by NGF
0.1 7.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.1 2.1 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.1 2.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.1 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 1.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.0 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 0.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.4 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 4.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 0.9 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 2.1 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 1.3 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 1.0 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 3.5 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.5 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 2.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 2.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.6 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.7 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.9 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.6 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.1 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 3.5 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.3 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 1.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.8 REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane