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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TFAP4_MSC

Z-value: 1.08

Motif logo

Transcription factors associated with TFAP4_MSC

Gene Symbol Gene ID Gene Info
ENSG00000090447.7 transcription factor AP-4
ENSG00000178860.8 musculin

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFAP4hg19_v2_chr16_-_4323015_43230760.161.5e-02Click!
MSChg19_v2_chr8_-_72756667_727567360.054.7e-01Click!

Activity profile of TFAP4_MSC motif

Sorted Z-values of TFAP4_MSC motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_123752624 24.95 ENST00000542174.1
ENST00000535796.1
cyclin-dependent kinase 2 associated protein 1
chr11_-_111783595 24.16 ENST00000528628.1
crystallin, alpha B
chr1_+_10271674 20.91 ENST00000377086.1
kinesin family member 1B
chr7_-_30029574 19.45 ENST00000426154.1
ENST00000421434.1
ENST00000434476.2
secernin 1
chr7_-_30029367 18.87 ENST00000242059.5
secernin 1
chr5_+_102201722 18.74 ENST00000274392.9
ENST00000455264.2
peptidylglycine alpha-amidating monooxygenase
chr16_-_21289627 17.74 ENST00000396023.2
ENST00000415987.2
crystallin, mu
chr5_+_102201509 17.29 ENST00000348126.2
ENST00000379787.4
peptidylglycine alpha-amidating monooxygenase
chr19_+_18208603 14.64 ENST00000262811.6
microtubule associated serine/threonine kinase 3
chr18_-_74728998 14.05 ENST00000359645.3
ENST00000397875.3
ENST00000397869.3
ENST00000578193.1
ENST00000578873.1
ENST00000397866.4
ENST00000528160.1
ENST00000527041.1
ENST00000526111.1
ENST00000397865.5
ENST00000382582.3
myelin basic protein
chr15_-_42749711 13.82 ENST00000565611.1
ENST00000263805.4
ENST00000565948.1
zinc finger protein 106
chr5_-_16936340 13.58 ENST00000507288.1
ENST00000513610.1
myosin X
chr2_+_54198210 12.90 ENST00000607452.1
ENST00000422521.2
acylphosphatase 2, muscle type
chr14_+_90863327 12.45 ENST00000356978.4
calmodulin 1 (phosphorylase kinase, delta)
chr5_+_102201430 12.15 ENST00000438793.3
ENST00000346918.2
peptidylglycine alpha-amidating monooxygenase
chr5_+_102201687 11.54 ENST00000304400.7
peptidylglycine alpha-amidating monooxygenase
chr3_+_159570722 11.38 ENST00000482804.1
schwannomin interacting protein 1
chr12_+_56473628 11.03 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr11_-_117748138 10.81 ENST00000527717.1
FXYD domain containing ion transport regulator 6
chr11_-_117747607 10.79 ENST00000540359.1
ENST00000539526.1
FXYD domain containing ion transport regulator 6
chr6_+_30851840 10.67 ENST00000511510.1
ENST00000376569.3
ENST00000376575.3
ENST00000376570.4
ENST00000446312.1
ENST00000504927.1
discoidin domain receptor tyrosine kinase 1
chr11_-_117747434 10.64 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD domain containing ion transport regulator 6
chr1_+_153600869 10.50 ENST00000292169.1
ENST00000368696.3
ENST00000436839.1
S100 calcium binding protein A1
chr3_-_178790057 10.43 ENST00000311417.2
zinc finger, matrin-type 3
chr3_-_33700933 10.02 ENST00000480013.1
cytoplasmic linker associated protein 2
chr1_-_86043921 9.93 ENST00000535924.2
dimethylarginine dimethylaminohydrolase 1
chr6_+_30852130 9.57 ENST00000428153.2
ENST00000376568.3
ENST00000452441.1
ENST00000515219.1
discoidin domain receptor tyrosine kinase 1
chr21_-_27542972 9.37 ENST00000346798.3
ENST00000439274.2
ENST00000354192.3
ENST00000348990.5
ENST00000357903.3
ENST00000358918.3
ENST00000359726.3
amyloid beta (A4) precursor protein
chr3_-_33700589 9.30 ENST00000461133.3
ENST00000496954.2
cytoplasmic linker associated protein 2
chr8_-_110660999 9.24 ENST00000424158.2
ENST00000533895.1
ENST00000446070.2
ENST00000528331.1
ENST00000526302.1
ENST00000433638.1
ENST00000408908.2
ENST00000524720.1
syntabulin (syntaxin-interacting)
chr10_-_97321165 9.10 ENST00000306402.6
sorbin and SH3 domain containing 1
chr2_-_225811747 8.17 ENST00000409592.3
dedicator of cytokinesis 10
chr3_+_167453493 8.15 ENST00000295777.5
ENST00000472747.2
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr11_-_66725837 8.10 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
pyruvate carboxylase
chr14_-_67826486 8.00 ENST00000555431.1
ENST00000554236.1
ENST00000555474.1
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr15_+_42696954 7.63 ENST00000337571.4
ENST00000569136.1
calpain 3, (p94)
chr15_+_42696992 7.48 ENST00000561817.1
calpain 3, (p94)
chr15_+_42697018 7.38 ENST00000397204.4
calpain 3, (p94)
chr12_-_50297638 7.20 ENST00000320634.3
Fas apoptotic inhibitory molecule 2
chr12_-_50298000 7.19 ENST00000550635.2
Fas apoptotic inhibitory molecule 2
chr1_-_150669604 6.95 ENST00000427665.1
ENST00000540514.1
golgi phosphoprotein 3-like
chr4_-_90759440 6.82 ENST00000336904.3
synuclein, alpha (non A4 component of amyloid precursor)
chr4_-_153303658 6.55 ENST00000296555.5
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr8_+_9413410 6.37 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr21_-_27543425 6.31 ENST00000448388.2
amyloid beta (A4) precursor protein
chr15_+_42697065 6.28 ENST00000565559.1
calpain 3, (p94)
chr10_-_73611046 6.10 ENST00000394934.1
ENST00000394936.3
prosaposin
chr5_-_11589131 6.07 ENST00000511377.1
catenin (cadherin-associated protein), delta 2
chr19_-_34012674 5.80 ENST00000436370.3
ENST00000397032.4
ENST00000244137.7
peptidase D
chr2_+_11752379 5.76 ENST00000396123.1
growth regulation by estrogen in breast cancer 1
chr2_-_183903133 5.69 ENST00000361354.4
NCK-associated protein 1
chr12_-_120315074 5.62 ENST00000261833.7
ENST00000392521.2
citron (rho-interacting, serine/threonine kinase 21)
chr22_+_38071615 5.44 ENST00000215909.5
lectin, galactoside-binding, soluble, 1
chr8_-_49834299 5.43 ENST00000396822.1
snail family zinc finger 2
chr11_+_62475130 5.39 ENST00000294117.5
guanine nucleotide binding protein (G protein), gamma 3
chr10_+_13142225 5.39 ENST00000378747.3
optineurin
chr3_+_69134124 5.32 ENST00000478935.1
ADP-ribosylation-like factor 6 interacting protein 5
chr2_-_176866978 5.31 ENST00000392540.2
ENST00000409660.1
ENST00000544803.1
ENST00000272748.4
KIAA1715
chr3_+_69134080 5.26 ENST00000273258.3
ADP-ribosylation-like factor 6 interacting protein 5
chr1_-_175712829 5.22 ENST00000367674.2
tenascin R
chr11_-_62474803 5.19 ENST00000533982.1
ENST00000360796.5
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr10_-_62149433 5.17 ENST00000280772.2
ankyrin 3, node of Ranvier (ankyrin G)
chr6_+_69942298 5.15 ENST00000238918.8
brain-specific angiogenesis inhibitor 3
chr10_+_13142075 5.14 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
optineurin
chr8_-_13134045 5.10 ENST00000512044.2
deleted in liver cancer 1
chr1_+_51701924 5.05 ENST00000242719.3
ring finger protein 11
chr8_-_30670053 4.97 ENST00000518564.1
protein phosphatase 2, catalytic subunit, beta isozyme
chr12_+_12938541 4.97 ENST00000356591.4
apolipoprotein L domain containing 1
chr2_-_74607390 4.93 ENST00000413111.1
ENST00000409567.3
ENST00000454119.1
ENST00000361874.3
ENST00000394003.3
dynactin 1
chr19_+_35521572 4.91 ENST00000262631.5
sodium channel, voltage-gated, type I, beta subunit
chr3_+_32147997 4.90 ENST00000282541.5
glycerol-3-phosphate dehydrogenase 1-like
chr1_+_15272271 4.88 ENST00000400797.3
kazrin, periplakin interacting protein
chr17_-_73851285 4.86 ENST00000589642.1
ENST00000593002.1
ENST00000590221.1
ENST00000344296.4
ENST00000587374.1
ENST00000585462.1
ENST00000433525.2
ENST00000254806.3
WW domain binding protein 2
chr10_+_1102721 4.76 ENST00000263150.4
WD repeat domain 37
chr10_-_97321112 4.74 ENST00000607232.1
ENST00000371227.4
ENST00000371249.2
ENST00000371247.2
ENST00000371246.2
ENST00000393949.1
ENST00000353505.5
ENST00000347291.4
sorbin and SH3 domain containing 1
chr8_-_49833978 4.53 ENST00000020945.1
snail family zinc finger 2
chr15_-_83240507 4.47 ENST00000564522.1
ENST00000398592.2
cytoplasmic polyadenylation element binding protein 1
chr4_-_46391805 4.43 ENST00000540012.1
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr6_-_128841503 4.43 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
protein tyrosine phosphatase, receptor type, K
chr6_+_150070831 4.39 ENST00000367380.5
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr10_-_73848764 4.31 ENST00000317376.4
ENST00000412663.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr16_-_31106211 4.29 ENST00000532364.1
ENST00000529564.1
ENST00000319788.7
ENST00000354895.4
ENST00000394975.2
Uncharacterized protein
vitamin K epoxide reductase complex, subunit 1
chr16_-_67514982 4.23 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr2_+_136343820 4.21 ENST00000410054.1
R3H domain containing 1
chr18_+_54318616 4.07 ENST00000254442.3
WD repeat domain 7
chr19_+_35521616 4.06 ENST00000595652.1
sodium channel, voltage-gated, type I, beta subunit
chr10_+_88428206 4.06 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LIM domain binding 3
chrX_-_10851762 4.05 ENST00000380785.1
ENST00000380787.1
midline 1 (Opitz/BBB syndrome)
chr18_-_5419797 4.03 ENST00000542146.1
ENST00000427684.2
erythrocyte membrane protein band 4.1-like 3
chr11_-_1330834 3.98 ENST00000525159.1
ENST00000317204.6
ENST00000542915.1
ENST00000527938.1
ENST00000530541.1
ENST00000263646.7
toll interacting protein
chrX_-_137793826 3.96 ENST00000315930.6
fibroblast growth factor 13
chr4_+_114214125 3.95 ENST00000509550.1
ankyrin 2, neuronal
chr7_+_48128816 3.91 ENST00000395564.4
uridine phosphorylase 1
chr4_-_46391367 3.84 ENST00000503806.1
ENST00000356504.1
ENST00000514090.1
ENST00000506961.1
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr15_+_63354769 3.80 ENST00000558910.1
tropomyosin 1 (alpha)
chr10_+_102790980 3.73 ENST00000393459.1
ENST00000224807.5
sideroflexin 3
chr7_+_48128194 3.69 ENST00000416681.1
ENST00000331803.4
ENST00000432131.1
uridine phosphorylase 1
chr4_-_52904425 3.67 ENST00000535450.1
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
chr17_-_1090599 3.67 ENST00000544583.2
active BCR-related
chr8_+_98788003 3.65 ENST00000521545.2
lysosomal protein transmembrane 4 beta
chr7_+_48128854 3.64 ENST00000436673.1
ENST00000429491.2
uridine phosphorylase 1
chr7_-_100065686 3.56 ENST00000423266.1
ENST00000456330.1
TSC22 domain family, member 4
chr7_+_48128316 3.54 ENST00000341253.4
uridine phosphorylase 1
chr8_-_72274467 3.42 ENST00000340726.3
eyes absent homolog 1 (Drosophila)
chr4_+_154178520 3.41 ENST00000433687.1
tripartite motif containing 2
chr3_-_52001448 3.39 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
poly(rC) binding protein 4
chr6_-_132834184 3.39 ENST00000367941.2
ENST00000367937.4
syntaxin 7
chr20_+_62697564 3.38 ENST00000458442.1
transcription elongation factor A (SII), 2
chrX_+_135278908 3.37 ENST00000539015.1
ENST00000370683.1
four and a half LIM domains 1
chr12_-_54121212 3.30 ENST00000548263.1
ENST00000430117.2
ENST00000550804.1
ENST00000549173.1
ENST00000551900.1
ENST00000546619.1
ENST00000548177.1
ENST00000549349.1
calcium binding and coiled-coil domain 1
chr11_+_45918092 3.24 ENST00000395629.2
mitogen-activated protein kinase 8 interacting protein 1
chr17_+_3379284 3.19 ENST00000263080.2
aspartoacylase
chr16_-_31106048 3.17 ENST00000300851.6
vitamin K epoxide reductase complex, subunit 1
chr3_+_35721106 3.16 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
cAMP-regulated phosphoprotein, 21kDa
chr1_+_200708671 3.14 ENST00000358823.2
calmodulin regulated spectrin-associated protein family, member 2
chr16_-_5147743 3.14 ENST00000587133.1
ENST00000458008.4
ENST00000427587.4
family with sequence similarity 86, member A
chr19_+_36249057 3.10 ENST00000301165.5
ENST00000536950.1
ENST00000537459.1
ENST00000421853.2
chromosome 19 open reading frame 55
chr4_+_7045042 3.08 ENST00000310074.7
ENST00000512388.1
transcriptional adaptor 2B
chr15_-_72523924 3.05 ENST00000566809.1
ENST00000567087.1
ENST00000569050.1
ENST00000568883.1
pyruvate kinase, muscle
chrX_-_9734004 3.05 ENST00000467482.1
ENST00000380929.2
G protein-coupled receptor 143
chr12_-_54121261 3.04 ENST00000549784.1
ENST00000262059.4
calcium binding and coiled-coil domain 1
chr16_+_23652773 2.88 ENST00000563998.1
ENST00000568589.1
ENST00000568272.1
dynactin 5 (p25)
chr7_-_104909435 2.85 ENST00000357311.3
SRSF protein kinase 2
chr11_+_61722629 2.81 ENST00000526988.1
bestrophin 1
chr11_+_71498552 2.77 ENST00000346333.6
ENST00000359244.4
ENST00000426628.2
family with sequence similarity 86, member C1
chr19_-_48018203 2.76 ENST00000595227.1
ENST00000593761.1
ENST00000263354.3
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr8_+_104033296 2.75 ENST00000521514.1
ENST00000518738.1
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
chr8_-_30670384 2.75 ENST00000221138.4
ENST00000518243.1
protein phosphatase 2, catalytic subunit, beta isozyme
chr22_+_19705928 2.74 ENST00000383045.3
ENST00000438754.2
septin 5
chr11_-_796197 2.73 ENST00000530360.1
ENST00000528606.1
ENST00000320230.5
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr7_+_99699280 2.64 ENST00000421755.1
adaptor-related protein complex 4, mu 1 subunit
chr9_+_99212403 2.62 ENST00000375251.3
ENST00000375249.4
hyaluronan binding protein 4
chr1_-_182360498 2.56 ENST00000417584.2
glutamate-ammonia ligase
chr6_+_150070857 2.52 ENST00000544496.1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr7_+_99699179 2.49 ENST00000438383.1
ENST00000429084.1
ENST00000359593.4
ENST00000439416.1
adaptor-related protein complex 4, mu 1 subunit
chr17_-_41174424 2.43 ENST00000355653.3
vesicle amine transport 1
chr17_-_7145106 2.40 ENST00000577035.1
GABA(A) receptor-associated protein
chr12_-_49525175 2.39 ENST00000336023.5
ENST00000550367.1
ENST00000552984.1
ENST00000547476.1
tubulin, alpha 1b
chr20_+_53092123 2.39 ENST00000262593.5
docking protein 5
chr12_-_56122426 2.37 ENST00000551173.1
CD63 molecule
chr11_-_1587166 2.36 ENST00000331588.4
dual specificity phosphatase 8
chr7_-_82792215 2.36 ENST00000333891.9
ENST00000423517.2
piccolo presynaptic cytomatrix protein
chr17_+_57232690 2.35 ENST00000262293.4
proline rich 11
chr3_-_183273477 2.33 ENST00000341319.3
kelch-like family member 6
chr8_-_57358432 2.28 ENST00000517415.1
ENST00000314922.3
proenkephalin
chr6_+_110012462 2.27 ENST00000441478.2
ENST00000230124.3
FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)
chr3_-_15106747 2.26 ENST00000449354.2
ENST00000444840.2
ENST00000253686.2
mitochondrial ribosomal protein S25
chr12_-_30887948 2.26 ENST00000433722.2
caprin family member 2
chr20_-_44485835 2.25 ENST00000457981.1
ENST00000426915.1
ENST00000217455.4
acyl-CoA thioesterase 8
chr3_-_50360192 2.22 ENST00000442581.1
ENST00000447092.1
ENST00000357750.4
hyaluronoglucosaminidase 2
chr7_-_108166505 2.21 ENST00000426128.2
ENST00000427008.1
ENST00000388728.5
ENST00000257694.8
ENST00000422087.1
ENST00000453144.1
ENST00000436062.1
patatin-like phospholipase domain containing 8
chr14_+_45431379 2.20 ENST00000361577.3
ENST00000361462.2
ENST00000382233.2
family with sequence similarity 179, member B
chr5_+_113697983 2.20 ENST00000264773.3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr16_+_66914264 2.19 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr12_+_69201923 2.16 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2 oncogene, E3 ubiquitin protein ligase
chrX_+_128872998 2.15 ENST00000371106.3
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr9_-_35111420 2.14 ENST00000378557.1
family with sequence similarity 214, member B
chr19_+_10527449 2.12 ENST00000592685.1
ENST00000380702.2
phosphodiesterase 4A, cAMP-specific
chr19_+_16830774 2.11 ENST00000524140.2
NACHT and WD repeat domain containing 1
chr1_+_155051305 2.10 ENST00000368408.3
ephrin-A3
chr11_+_32112431 2.10 ENST00000054950.3
reticulocalbin 1, EF-hand calcium binding domain
chr12_-_50677255 2.09 ENST00000551691.1
ENST00000394943.3
ENST00000341247.4
LIM domain and actin binding 1
chr1_-_165414414 2.08 ENST00000359842.5
retinoid X receptor, gamma
chr16_+_83932684 2.07 ENST00000262430.4
malonyl-CoA decarboxylase
chr15_-_83680325 2.07 ENST00000508990.2
ENST00000510873.2
ENST00000538348.2
ENST00000451195.3
ENST00000513601.2
ENST00000304177.5
ENST00000565712.1
chromosome 15 open reading frame 40
chr1_-_85462623 2.06 ENST00000370608.3
mucolipin 2
chr2_+_192110199 2.01 ENST00000304164.4
myosin IB
chr9_+_17134980 2.01 ENST00000380647.3
centlein, centrosomal protein
chr4_-_186125077 1.98 ENST00000458385.2
ENST00000514798.1
ENST00000296775.6
KIAA1430
chr17_-_47755338 1.98 ENST00000508805.1
ENST00000515508.2
ENST00000451526.2
ENST00000507970.1
speckle-type POZ protein
chrX_+_21857764 1.97 ENST00000365779.2
membrane-bound transcription factor peptidase, site 2
chr17_+_68071458 1.94 ENST00000589377.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr2_-_136288113 1.94 ENST00000401392.1
zinc finger, RAN-binding domain containing 3
chr6_-_34524049 1.92 ENST00000374037.3
SAM pointed domain containing ETS transcription factor
chr8_-_72274095 1.89 ENST00000303824.7
eyes absent homolog 1 (Drosophila)
chr17_+_7461849 1.89 ENST00000338784.4
tumor necrosis factor (ligand) superfamily, member 13
chr3_+_49058444 1.88 ENST00000326925.6
ENST00000395458.2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr10_-_73848531 1.87 ENST00000373109.2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr2_-_69870747 1.86 ENST00000409068.1
AP2 associated kinase 1
chr15_+_43809797 1.86 ENST00000399453.1
ENST00000300231.5
microtubule-associated protein 1A
chr5_+_54455946 1.86 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
glutathione peroxidase 8 (putative)
chr19_-_2151523 1.85 ENST00000350812.6
ENST00000355272.6
ENST00000356926.4
ENST00000345016.5
adaptor-related protein complex 3, delta 1 subunit
chr8_+_104033277 1.85 ENST00000518857.1
ENST00000395862.3
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
chr3_-_69435224 1.81 ENST00000398540.3
FERM domain containing 4B
chr12_+_122150646 1.80 ENST00000449592.2
transmembrane protein 120B
chr6_+_96463840 1.79 ENST00000302103.5
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr5_+_95066823 1.78 ENST00000506817.1
ENST00000379982.3
Rho-related BTB domain containing 3
chr3_+_49507559 1.77 ENST00000421560.1
ENST00000308775.2
ENST00000545947.1
ENST00000541308.1
ENST00000539901.1
ENST00000538711.1
ENST00000418588.1
dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr8_+_107738240 1.77 ENST00000449762.2
ENST00000297447.6
oxidation resistance 1
chrX_-_30326445 1.75 ENST00000378963.1
nuclear receptor subfamily 0, group B, member 1
chr19_-_59070239 1.75 ENST00000595957.1
ENST00000253023.3
ubiquitin-conjugating enzyme E2M
chr18_+_55816546 1.71 ENST00000435432.2
ENST00000357895.5
ENST00000586263.1
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr11_-_1785139 1.71 ENST00000236671.2
cathepsin D
chr17_+_7482785 1.69 ENST00000250092.6
ENST00000380498.6
ENST00000584502.1
CD68 molecule
chr11_-_47270341 1.68 ENST00000529444.1
ENST00000530453.1
ENST00000537863.1
ENST00000529788.1
ENST00000444355.2
ENST00000527256.1
ENST00000529663.1
ENST00000256997.3
acid phosphatase 2, lysosomal
chr21_+_34398153 1.67 ENST00000382357.3
ENST00000430860.1
ENST00000333337.3
oligodendrocyte lineage transcription factor 2
chr6_-_34524093 1.65 ENST00000544425.1
SAM pointed domain containing ETS transcription factor
chr8_+_124428959 1.62 ENST00000287387.2
ENST00000523984.1
WDYHV motif containing 1
chr3_+_132136331 1.60 ENST00000260818.6
DnaJ (Hsp40) homolog, subfamily C, member 13
chr1_+_19638788 1.59 ENST00000375155.3
ENST00000375153.3
ENST00000400548.2
PQ loop repeat containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP4_MSC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
14.9 59.7 GO:0018032 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
7.0 20.9 GO:1904647 response to rotenone(GO:1904647)
4.8 28.8 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
3.7 14.8 GO:0006218 uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
3.3 10.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
3.1 15.7 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
3.0 9.0 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
2.8 14.1 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
2.7 8.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
2.4 19.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
2.2 20.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
2.1 6.4 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
1.6 17.7 GO:0006554 lysine catabolic process(GO:0006554)
1.5 1.5 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
1.4 6.8 GO:0051620 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
1.4 5.4 GO:0002317 plasma cell differentiation(GO:0002317)
1.3 24.2 GO:0007021 tubulin complex assembly(GO:0007021)
1.3 10.6 GO:0002036 regulation of L-glutamate transport(GO:0002036)
1.3 4.0 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.3 10.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
1.3 6.5 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
1.3 5.2 GO:0072658 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
1.2 4.9 GO:0042441 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
1.2 4.9 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
1.2 3.7 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
1.1 3.2 GO:0006533 aspartate catabolic process(GO:0006533)
1.0 14.4 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
1.0 11.4 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.9 8.7 GO:0042373 vitamin K metabolic process(GO:0042373)
0.8 4.0 GO:1990834 response to odorant(GO:1990834)
0.8 0.8 GO:0014901 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.8 6.9 GO:0030091 protein repair(GO:0030091)
0.8 9.9 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.7 2.2 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.7 4.9 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.6 2.6 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.6 4.9 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.6 3.1 GO:0048690 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.6 5.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.6 4.0 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.6 2.3 GO:0051866 general adaptation syndrome(GO:0051866)
0.6 5.7 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.6 4.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.6 1.7 GO:0021778 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.6 2.2 GO:0019087 transformation of host cell by virus(GO:0019087)
0.6 11.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.5 1.6 GO:1903401 L-lysine transmembrane transport(GO:1903401)
0.5 3.6 GO:0010454 negative regulation of cell fate commitment(GO:0010454) lung goblet cell differentiation(GO:0060480)
0.5 2.0 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.5 3.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.5 2.4 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.5 3.8 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.5 12.7 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.5 15.8 GO:0090383 phagosome acidification(GO:0090383)
0.5 2.8 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.5 1.4 GO:0097056 seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.4 2.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.4 1.3 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.4 26.7 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.4 2.1 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115) malonyl-CoA metabolic process(GO:2001293)
0.4 5.0 GO:0042118 endothelial cell activation(GO:0042118)
0.4 3.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.4 1.6 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.4 2.7 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.4 1.9 GO:0048478 replication fork protection(GO:0048478)
0.4 1.2 GO:0030575 nuclear body organization(GO:0030575)
0.4 3.4 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.4 4.7 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.3 1.7 GO:0035063 nuclear speck organization(GO:0035063)
0.3 5.1 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.3 3.7 GO:0055072 iron ion homeostasis(GO:0055072)
0.3 2.3 GO:0031642 negative regulation of myelination(GO:0031642)
0.3 1.0 GO:0072709 cellular response to sorbitol(GO:0072709)
0.3 3.7 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.3 6.1 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.3 1.2 GO:0007525 somatic muscle development(GO:0007525)
0.3 3.6 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.3 2.4 GO:0030578 PML body organization(GO:0030578)
0.3 6.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 3.5 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.3 1.2 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.3 1.1 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.3 0.6 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.3 3.2 GO:0048194 Golgi vesicle budding(GO:0048194)
0.3 0.8 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.3 2.6 GO:0033327 Leydig cell differentiation(GO:0033327)
0.2 1.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.2 5.1 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 1.0 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.2 0.7 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.2 4.0 GO:0036010 protein localization to endosome(GO:0036010)
0.2 1.4 GO:0023021 termination of signal transduction(GO:0023021)
0.2 1.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.2 14.4 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.2 2.9 GO:0035372 protein localization to microtubule(GO:0035372)
0.2 1.8 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.2 2.2 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.2 5.2 GO:0034389 lipid particle organization(GO:0034389)
0.2 2.8 GO:0030321 transepithelial chloride transport(GO:0030321)
0.2 2.4 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.2 2.2 GO:0016559 peroxisome fission(GO:0016559)
0.2 1.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 2.1 GO:1902959 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.2 2.5 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.2 1.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.2 1.8 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 2.1 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.2 0.7 GO:0019086 late viral transcription(GO:0019086)
0.2 2.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.2 2.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.2 4.8 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.2 0.3 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.2 1.3 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 1.1 GO:1905146 lysosomal lumen acidification(GO:0007042) lysosomal protein catabolic process(GO:1905146)
0.2 0.9 GO:0015811 L-cystine transport(GO:0015811)
0.2 1.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.2 0.6 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.4 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.1 1.0 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.1 1.8 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 3.1 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.1 6.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 2.3 GO:0002467 germinal center formation(GO:0002467)
0.1 2.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.6 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1 8.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 0.7 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 2.7 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.4 GO:0006788 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806)
0.1 1.6 GO:0034605 cellular response to heat(GO:0034605)
0.1 1.3 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.7 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1 2.2 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1 0.5 GO:0070253 somatostatin secretion(GO:0070253) oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 3.0 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 3.2 GO:0010107 potassium ion import(GO:0010107)
0.1 4.4 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.1 0.6 GO:0070980 biphenyl catabolic process(GO:0070980)
0.1 1.4 GO:0097062 dendritic spine maintenance(GO:0097062)
0.1 1.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 1.6 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.1 1.7 GO:0045116 protein neddylation(GO:0045116)
0.1 6.0 GO:0046677 response to antibiotic(GO:0046677)
0.1 1.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 1.5 GO:0033572 transferrin transport(GO:0033572)
0.1 1.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 10.0 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 7.8 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1 0.8 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 10.7 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.1 0.7 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1 0.4 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.3 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.1 2.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 3.4 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.1 0.8 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 3.7 GO:0045214 sarcomere organization(GO:0045214)
0.1 3.6 GO:0060976 coronary vasculature development(GO:0060976)
0.1 12.9 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.1 1.5 GO:0016540 protein autoprocessing(GO:0016540)
0.1 5.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 2.1 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.1 1.3 GO:0071625 vocalization behavior(GO:0071625)
0.1 3.3 GO:0035418 protein localization to synapse(GO:0035418)
0.1 0.8 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.1 0.2 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 3.5 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.1 5.4 GO:0030574 collagen catabolic process(GO:0030574)
0.1 0.7 GO:0010815 bradykinin catabolic process(GO:0010815)
0.1 0.4 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.4 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.4 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1 0.5 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.2 GO:0061743 motor learning(GO:0061743)
0.1 0.8 GO:0051775 response to redox state(GO:0051775)
0.1 1.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 1.5 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.5 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.1 1.8 GO:0007050 cell cycle arrest(GO:0007050)
0.1 1.0 GO:0006986 response to unfolded protein(GO:0006986)
0.1 0.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 4.6 GO:0007422 peripheral nervous system development(GO:0007422)
0.0 5.4 GO:0070268 cornification(GO:0070268)
0.0 1.7 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 2.1 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.7 GO:0060177 regulation of angiotensin levels in blood(GO:0002002) angiotensin maturation(GO:0002003) regulation of angiotensin metabolic process(GO:0060177)
0.0 0.9 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 1.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 4.4 GO:0007030 Golgi organization(GO:0007030)
0.0 1.2 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 6.3 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.0 0.7 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 1.0 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.0 0.1 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.4 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.0 1.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.9 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.2 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 2.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 1.0 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.5 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.2 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.2 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.3 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 3.0 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.0 1.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.0 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.9 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 1.5 GO:0017156 calcium ion regulated exocytosis(GO:0017156)
0.0 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.7 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.5 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.3 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.8 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.3 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 13.8 GO:0005899 insulin receptor complex(GO:0005899)
2.0 14.1 GO:0033269 internode region of axon(GO:0033269)
1.9 19.3 GO:0045180 basal cortex(GO:0045180)
1.7 15.7 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
1.5 24.2 GO:0097512 cardiac myofibril(GO:0097512)
1.0 3.1 GO:0072534 perineuronal net(GO:0072534)
0.9 6.5 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.9 4.6 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.9 5.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.8 4.9 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.8 4.0 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.8 4.8 GO:0070545 PeBoW complex(GO:0070545)
0.8 13.6 GO:0032433 filopodium tip(GO:0032433)
0.7 9.2 GO:0097433 dense body(GO:0097433)
0.7 2.8 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.6 3.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.6 47.5 GO:0030315 T-tubule(GO:0030315)
0.5 8.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.5 4.8 GO:0016011 dystroglycan complex(GO:0016011)
0.5 3.2 GO:0044294 dendritic growth cone(GO:0044294)
0.5 1.4 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.5 12.3 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.4 5.7 GO:0031209 SCAR complex(GO:0031209)
0.4 64.4 GO:0043204 perikaryon(GO:0043204)
0.4 2.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.4 22.0 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.4 18.1 GO:1904115 axon cytoplasm(GO:1904115)
0.4 4.0 GO:0033270 paranode region of axon(GO:0033270)
0.4 5.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.3 4.9 GO:0005869 dynactin complex(GO:0005869)
0.3 2.0 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.3 6.9 GO:0031143 pseudopodium(GO:0031143)
0.3 4.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 1.9 GO:0043596 nuclear replication fork(GO:0043596)
0.2 0.7 GO:0097427 microtubule bundle(GO:0097427)
0.2 1.6 GO:0071203 WASH complex(GO:0071203)
0.2 7.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 3.8 GO:0032059 bleb(GO:0032059)
0.2 7.9 GO:0031430 M band(GO:0031430)
0.2 1.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.2 7.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 4.9 GO:0030057 desmosome(GO:0030057)
0.2 1.8 GO:0042788 polysomal ribosome(GO:0042788)
0.2 1.0 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.2 3.1 GO:0030914 STAGA complex(GO:0030914)
0.2 13.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 1.7 GO:1990752 microtubule end(GO:1990752)
0.1 1.3 GO:0032009 early phagosome(GO:0032009)
0.1 2.4 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 2.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 14.5 GO:0005776 autophagosome(GO:0005776)
0.1 7.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.6 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 5.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 1.4 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 1.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.4 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 3.4 GO:0031201 SNARE complex(GO:0031201)
0.1 2.4 GO:0099738 cell cortex region(GO:0099738)
0.1 11.2 GO:0031985 Golgi cisterna(GO:0031985)
0.1 0.4 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 0.9 GO:0005883 neurofilament(GO:0005883)
0.1 6.3 GO:0043195 terminal bouton(GO:0043195)
0.1 1.4 GO:0042599 lamellar body(GO:0042599)
0.1 28.0 GO:0031965 nuclear membrane(GO:0031965)
0.1 2.1 GO:0071011 U5 snRNP(GO:0005682) precatalytic spliceosome(GO:0071011)
0.1 11.7 GO:0043197 dendritic spine(GO:0043197)
0.1 3.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 5.5 GO:0005901 caveola(GO:0005901)
0.1 4.4 GO:0005811 lipid particle(GO:0005811)
0.1 4.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 2.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 3.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 4.1 GO:0008021 synaptic vesicle(GO:0008021)
0.0 27.6 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 4.8 GO:0055037 recycling endosome(GO:0055037)
0.0 1.1 GO:0045178 basal part of cell(GO:0045178)
0.0 5.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 9.6 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 2.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 14.6 GO:0000790 nuclear chromatin(GO:0000790)
0.0 2.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 2.5 GO:0005814 centriole(GO:0005814)
0.0 0.5 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 3.1 GO:0043209 myelin sheath(GO:0043209)
0.0 2.2 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 3.4 GO:0030424 axon(GO:0030424)
0.0 0.6 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.9 GO:0030133 transport vesicle(GO:0030133)
0.0 0.5 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.9 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 1.9 GO:0031968 organelle outer membrane(GO:0031968)
0.0 5.9 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 1.4 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.5 GO:0032993 protein-DNA complex(GO:0032993)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
14.9 59.7 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
4.4 17.7 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
4.0 20.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
3.7 14.8 GO:0004850 uridine phosphorylase activity(GO:0004850)
3.0 9.0 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
2.2 8.7 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
2.1 12.9 GO:0003998 acylphosphatase activity(GO:0003998)
2.0 28.2 GO:0031432 titin binding(GO:0031432)
2.0 6.0 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
1.8 5.4 GO:0048030 disaccharide binding(GO:0048030)
1.7 43.9 GO:0016805 dipeptidase activity(GO:0016805)
1.5 13.6 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
1.4 6.8 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
1.3 4.0 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
1.3 7.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
1.2 12.5 GO:0051425 PTB domain binding(GO:0051425)
1.2 14.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.9 20.5 GO:0002162 dystroglycan binding(GO:0002162)
0.8 11.0 GO:0038132 neuregulin binding(GO:0038132)
0.8 6.5 GO:0050816 phosphothreonine binding(GO:0050816)
0.8 41.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.8 8.1 GO:0009374 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.8 23.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.8 3.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.8 6.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.7 2.2 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.7 25.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.7 33.4 GO:0019894 kinesin binding(GO:0019894)
0.6 2.6 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.6 8.3 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.6 12.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.6 1.2 GO:0070097 delta-catenin binding(GO:0070097)
0.6 2.3 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.6 2.2 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.5 1.6 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.5 2.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.5 3.2 GO:0004046 aminoacylase activity(GO:0004046)
0.5 1.4 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.5 9.5 GO:0044548 S100 protein binding(GO:0044548)
0.4 1.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.4 4.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.4 2.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.4 1.1 GO:0034046 poly(G) binding(GO:0034046)
0.3 1.7 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.3 2.0 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.3 2.3 GO:0001515 opioid peptide activity(GO:0001515)
0.3 6.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.3 3.4 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.3 5.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.3 5.9 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.3 4.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.3 14.6 GO:0005158 insulin receptor binding(GO:0005158)
0.2 2.7 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2 6.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 2.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.2 3.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 0.7 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.2 1.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2 4.9 GO:0070840 dynein complex binding(GO:0070840)
0.2 1.8 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.2 2.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 1.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.2 2.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.2 0.8 GO:0017040 ceramidase activity(GO:0017040)
0.2 1.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 0.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 3.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 2.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.2 1.6 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2 0.8 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2 26.3 GO:0044325 ion channel binding(GO:0044325)
0.2 1.9 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 2.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2 0.9 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.4 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 1.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 2.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 1.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.6 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 2.4 GO:0005522 profilin binding(GO:0005522)
0.1 10.8 GO:0002039 p53 binding(GO:0002039)
0.1 0.4 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 2.4 GO:0050811 GABA receptor binding(GO:0050811)
0.1 6.2 GO:0005080 protein kinase C binding(GO:0005080)
0.1 2.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 2.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.4 GO:0070984 SET domain binding(GO:0070984)
0.1 0.6 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.9 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 11.3 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 3.6 GO:0030552 cAMP binding(GO:0030552)
0.1 1.2 GO:0035240 dopamine binding(GO:0035240)
0.1 1.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 7.3 GO:0008013 beta-catenin binding(GO:0008013)
0.1 1.5 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 1.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 1.5 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 1.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.8 GO:0000217 DNA secondary structure binding(GO:0000217)
0.1 2.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.0 GO:0032183 SUMO binding(GO:0032183)
0.1 1.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 8.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 7.8 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.1 1.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 1.3 GO:0005272 sodium channel activity(GO:0005272)
0.1 2.1 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0 2.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842) ubiquitin-like protein transferase activity(GO:0019787)
0.0 4.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 1.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 2.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:1901612 cardiolipin binding(GO:1901612)
0.0 1.0 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.7 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 2.1 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.3 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 1.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 2.2 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 1.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 3.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 2.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 2.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0003774 motor activity(GO:0003774)
0.0 1.1 GO:0042287 MHC protein binding(GO:0042287)
0.0 2.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.8 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 2.6 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 2.1 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.5 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.3 GO:0002020 protease binding(GO:0002020)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.9 GO:0019905 syntaxin binding(GO:0019905)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 38.9 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.4 11.0 PID ERBB NETWORK PATHWAY