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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TLX1_NFIC

Z-value: 2.07

Motif logo

Transcription factors associated with TLX1_NFIC

Gene Symbol Gene ID Gene Info
ENSG00000107807.8 T cell leukemia homeobox 1
ENSG00000141905.13 nuclear factor I C

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFIChg19_v2_chr19_+_3366547_33666190.452.9e-12Click!
TLX1hg19_v2_chr10_+_102891048_1028910780.351.3e-07Click!

Activity profile of TLX1_NFIC motif

Sorted Z-values of TLX1_NFIC motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_-_74728998 76.22 ENST00000359645.3
ENST00000397875.3
ENST00000397869.3
ENST00000578193.1
ENST00000578873.1
ENST00000397866.4
ENST00000528160.1
ENST00000527041.1
ENST00000526111.1
ENST00000397865.5
ENST00000382582.3
myelin basic protein
chr16_+_226658 70.91 ENST00000320868.5
ENST00000397797.1
hemoglobin, alpha 1
chr8_-_27468842 66.99 ENST00000523500.1
clusterin
chr11_-_111783919 62.47 ENST00000531198.1
ENST00000533879.1
crystallin, alpha B
chr11_-_111784005 53.52 ENST00000527899.1
crystallin, alpha B
chr3_-_58613323 52.84 ENST00000474531.1
ENST00000465970.1
family with sequence similarity 107, member A
chr9_+_139871948 52.40 ENST00000224167.2
ENST00000457950.1
ENST00000371625.3
ENST00000371623.3
prostaglandin D2 synthase 21kDa (brain)
chr8_-_27468945 52.25 ENST00000405140.3
clusterin
chr16_+_222846 49.53 ENST00000251595.6
ENST00000397806.1
hemoglobin, alpha 2
chr11_-_111781454 49.17 ENST00000533280.1
crystallin, alpha B
chrX_-_102319092 47.12 ENST00000372728.3
brain expressed, X-linked 1
chr8_-_27469196 46.57 ENST00000546343.1
ENST00000560566.1
clusterin
chrX_+_102631844 44.87 ENST00000372634.1
ENST00000299872.7
nerve growth factor receptor (TNFRSF16) associated protein 1
chrX_+_102631248 41.29 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr14_+_73704201 37.80 ENST00000340738.5
ENST00000427855.1
ENST00000381166.3
papilin, proteoglycan-like sulfated glycoprotein
chr12_+_66218212 33.56 ENST00000393578.3
ENST00000425208.2
ENST00000536545.1
ENST00000354636.3
high mobility group AT-hook 2
chr22_-_37213045 29.77 ENST00000406910.2
ENST00000417718.2
parvalbumin
chr8_+_24772455 29.56 ENST00000433454.2
neurofilament, medium polypeptide
chr8_-_42065187 29.28 ENST00000270189.6
ENST00000352041.3
ENST00000220809.4
plasminogen activator, tissue
chr17_-_42992856 27.11 ENST00000588316.1
ENST00000435360.2
ENST00000586793.1
ENST00000588735.1
ENST00000588037.1
ENST00000592320.1
ENST00000253408.5
glial fibrillary acidic protein
chr1_+_65775204 27.05 ENST00000371069.4
DnaJ (Hsp40) homolog, subfamily C, member 6
chr22_-_37213554 26.42 ENST00000443735.1
parvalbumin
chr14_+_85996471 26.37 ENST00000330753.4
fibronectin leucine rich transmembrane protein 2
chr22_+_40390930 26.21 ENST00000333407.6
family with sequence similarity 83, member F
chr16_-_19896220 25.82 ENST00000562469.1
ENST00000300571.2
G protein-coupled receptor, family C, group 5, member B
chr10_+_106034884 24.93 ENST00000369707.2
ENST00000429569.2
glutathione S-transferase omega 2
chr8_-_42065075 24.43 ENST00000429089.2
ENST00000519510.1
ENST00000429710.2
ENST00000524009.1
plasminogen activator, tissue
chrX_-_13956737 24.42 ENST00000454189.2
glycoprotein M6B
chr13_+_113622757 23.82 ENST00000375604.2
MCF.2 cell line derived transforming sequence-like
chr8_-_80680078 23.74 ENST00000337919.5
ENST00000354724.3
hes-related family bHLH transcription factor with YRPW motif 1
chr5_-_73937244 22.32 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ectodermal-neural cortex 1 (with BTB domain)
chr12_-_56106060 22.12 ENST00000452168.2
integrin, alpha 7
chr13_+_113622810 21.07 ENST00000397030.1
MCF.2 cell line derived transforming sequence-like
chr6_+_31949801 20.76 ENST00000428956.2
ENST00000498271.1
complement component 4A (Rodgers blood group)
chr21_-_28217721 19.27 ENST00000284984.3
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr22_+_41763274 18.95 ENST00000406644.3
thyrotrophic embryonic factor
chr7_+_116165038 18.84 ENST00000393470.1
caveolin 1, caveolae protein, 22kDa
chr6_+_31982539 18.39 ENST00000435363.2
ENST00000425700.2
complement component 4B (Chido blood group)
chr14_+_105939276 18.33 ENST00000483017.3
cysteine-rich protein 2
chr3_+_14989186 17.94 ENST00000435454.1
ENST00000323373.6
nuclear receptor subfamily 2, group C, member 2
chr2_-_217560248 17.26 ENST00000233813.4
insulin-like growth factor binding protein 5
chr9_+_124030338 16.60 ENST00000449773.1
ENST00000432226.1
ENST00000436847.1
ENST00000394353.2
ENST00000449733.1
ENST00000412819.1
ENST00000341272.2
ENST00000373808.2
gelsolin
chr2_+_102721023 15.21 ENST00000409589.1
ENST00000409329.1
interleukin 1 receptor, type I
chr6_+_29555683 14.82 ENST00000383640.2
olfactory receptor, family 2, subfamily H, member 2
chr17_-_26903900 14.52 ENST00000395319.3
ENST00000581807.1
ENST00000584086.1
ENST00000395321.2
aldolase C, fructose-bisphosphate
chr6_-_46922659 14.13 ENST00000265417.7
G protein-coupled receptor 116
chr14_+_24867992 14.13 ENST00000382554.3
NYN domain and retroviral integrase containing
chr1_+_110453109 13.83 ENST00000525659.1
colony stimulating factor 1 (macrophage)
chrX_+_46937745 13.14 ENST00000397180.1
ENST00000457380.1
ENST00000352078.4
regucalcin
chr20_+_44034804 13.09 ENST00000357275.2
ENST00000372720.3
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr3_-_12200851 12.95 ENST00000287814.4
TIMP metallopeptidase inhibitor 4
chr7_-_37024665 12.85 ENST00000396040.2
engulfment and cell motility 1
chr2_-_238322770 12.78 ENST00000472056.1
collagen, type VI, alpha 3
chr6_+_123100620 12.76 ENST00000368444.3
fatty acid binding protein 7, brain
chr2_-_238323007 12.60 ENST00000295550.4
collagen, type VI, alpha 3
chr17_+_38599693 12.37 ENST00000542955.1
ENST00000269593.4
insulin-like growth factor binding protein 4
chr14_-_50999190 12.32 ENST00000557390.1
mitogen-activated protein kinase kinase kinase kinase 5
chr2_-_238322800 12.29 ENST00000392004.3
ENST00000433762.1
ENST00000347401.3
ENST00000353578.4
ENST00000346358.4
ENST00000392003.2
collagen, type VI, alpha 3
chr11_-_117186946 12.18 ENST00000313005.6
ENST00000528053.1
beta-site APP-cleaving enzyme 1
chr11_+_1244288 11.78 ENST00000529681.1
ENST00000447027.1
mucin 5B, oligomeric mucus/gel-forming
chr1_+_156096336 11.77 ENST00000504687.1
ENST00000473598.2
lamin A/C
chr1_+_10271674 11.77 ENST00000377086.1
kinesin family member 1B
chr12_+_119616447 11.52 ENST00000281938.2
heat shock 22kDa protein 8
chr14_+_85996507 11.31 ENST00000554746.1
fibronectin leucine rich transmembrane protein 2
chr9_-_79520989 11.17 ENST00000376713.3
ENST00000376718.3
ENST00000428286.1
prune homolog 2 (Drosophila)
chr9_-_130616915 11.06 ENST00000344849.3
endoglin
chr12_+_13349650 11.01 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
epithelial membrane protein 1
chr16_+_23765948 10.96 ENST00000300113.2
calcineurin-like EF-hand protein 2
chr8_-_145701718 10.78 ENST00000377317.4
forkhead box H1
chr19_+_45312347 10.78 ENST00000270233.6
ENST00000591520.1
basal cell adhesion molecule (Lutheran blood group)
chr12_+_57522258 10.76 ENST00000553277.1
ENST00000243077.3
low density lipoprotein receptor-related protein 1
chr20_+_34742650 10.73 ENST00000373945.1
ENST00000338074.2
erythrocyte membrane protein band 4.1-like 1
chr6_+_150920999 10.69 ENST00000367328.1
ENST00000367326.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr6_+_39760783 10.69 ENST00000398904.2
ENST00000538976.1
dishevelled associated activator of morphogenesis 2
chr5_-_115872142 10.33 ENST00000510263.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr5_+_150020214 10.30 ENST00000307662.4
synaptopodin
chr9_-_130617029 10.27 ENST00000373203.4
endoglin
chr1_-_95392635 9.93 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
calponin 3, acidic
chr3_+_53880588 9.89 ENST00000288167.3
ENST00000494338.1
interleukin 17 receptor B
chr6_-_53013620 9.87 ENST00000259803.7
glial cells missing homolog 1 (Drosophila)
chr1_+_110453462 9.63 ENST00000488198.1
colony stimulating factor 1 (macrophage)
chr1_+_220960033 9.54 ENST00000366910.5
mitochondrial amidoxime reducing component 1
chr9_-_23821842 9.51 ENST00000544538.1
ELAV like neuron-specific RNA binding protein 2
chrX_-_133119476 9.42 ENST00000543339.1
glypican 3
chr20_+_44034676 9.41 ENST00000372723.3
ENST00000372722.3
dysbindin (dystrobrevin binding protein 1) domain containing 2
chrX_-_133119670 9.38 ENST00000394299.2
glypican 3
chr1_-_16344500 9.33 ENST00000406363.2
ENST00000411503.1
ENST00000545268.1
ENST00000487046.1
heat shock 27kDa protein family, member 7 (cardiovascular)
chr16_-_2264779 9.33 ENST00000333503.7
phosphoglycolate phosphatase
chr11_+_74862140 9.31 ENST00000525650.1
ENST00000454962.2
solute carrier organic anion transporter family, member 2B1
chr1_-_2323140 9.25 ENST00000378531.3
ENST00000378529.3
MORN repeat containing 1
chr8_+_85097110 9.13 ENST00000517638.1
ENST00000522647.1
RALY RNA binding protein-like
chr12_+_53491220 8.95 ENST00000548547.1
ENST00000301464.3
insulin-like growth factor binding protein 6
chr1_+_110453608 8.86 ENST00000369801.1
colony stimulating factor 1 (macrophage)
chr7_+_86273700 8.83 ENST00000546348.1
glutamate receptor, metabotropic 3
chr9_-_14180778 8.43 ENST00000380924.1
ENST00000543693.1
nuclear factor I/B
chr19_-_36247910 8.41 ENST00000587965.1
ENST00000004982.3
heat shock protein, alpha-crystallin-related, B6
chr5_+_92919043 8.41 ENST00000327111.3
nuclear receptor subfamily 2, group F, member 1
chr9_-_13279589 8.40 ENST00000319217.7
multiple PDZ domain protein
chr8_-_13134045 8.40 ENST00000512044.2
deleted in liver cancer 1
chr22_-_46450024 8.27 ENST00000396008.2
ENST00000333761.1
chromosome 22 open reading frame 26
chr7_+_86273952 8.27 ENST00000536043.1
glutamate receptor, metabotropic 3
chr9_-_13279563 8.25 ENST00000541718.1
multiple PDZ domain protein
chr8_-_18541603 8.23 ENST00000428502.2
pleckstrin and Sec7 domain containing 3
chr1_+_179262905 8.22 ENST00000539888.1
ENST00000540564.1
ENST00000535686.1
ENST00000367619.3
sterol O-acyltransferase 1
chr1_+_110453203 8.18 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
colony stimulating factor 1 (macrophage)
chr10_+_17271266 8.04 ENST00000224237.5
vimentin
chr15_-_40213080 8.01 ENST00000561100.1
G protein-coupled receptor 176
chr19_+_58111241 7.88 ENST00000597700.1
ENST00000332854.6
ENST00000597864.1
zinc finger protein 530
chr12_+_6644443 7.74 ENST00000396858.1
glyceraldehyde-3-phosphate dehydrogenase
chrX_-_133119895 7.73 ENST00000370818.3
glypican 3
chr5_-_111093406 7.73 ENST00000379671.3
neuronal regeneration related protein
chr19_+_10397621 7.71 ENST00000380770.3
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr20_+_19867150 7.57 ENST00000255006.6
Ras and Rab interactor 2
chr1_-_243418621 7.56 ENST00000366544.1
ENST00000366543.1
centrosomal protein 170kDa
chr19_+_10397648 7.49 ENST00000340992.4
ENST00000393717.2
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr20_-_60942361 7.46 ENST00000252999.3
laminin, alpha 5
chr21_+_46875424 7.46 ENST00000359759.4
collagen, type XVIII, alpha 1
chr12_-_124457371 7.44 ENST00000238156.3
ENST00000545037.1
coiled-coil domain containing 92
chr21_+_46875395 7.25 ENST00000355480.5
collagen, type XVIII, alpha 1
chr7_+_22766766 7.21 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
interleukin 6 (interferon, beta 2)
chr18_-_52989217 7.12 ENST00000570287.2
transcription factor 4
chr6_-_30043539 7.07 ENST00000376751.3
ENST00000244360.6
ring finger protein 39
chr3_-_114866084 7.07 ENST00000357258.3
zinc finger and BTB domain containing 20
chr5_-_111092930 6.99 ENST00000257435.7
neuronal regeneration related protein
chr7_+_86274145 6.96 ENST00000439827.1
ENST00000394720.2
ENST00000421579.1
glutamate receptor, metabotropic 3
chr17_+_26684604 6.94 ENST00000292114.3
ENST00000509083.1
transmembrane protein 199
chr8_-_82395461 6.87 ENST00000256104.4
fatty acid binding protein 4, adipocyte
chr1_-_161168834 6.82 ENST00000367995.3
ENST00000367996.5
ADAM metallopeptidase with thrombospondin type 1 motif, 4
chr11_+_61717336 6.81 ENST00000378042.3
bestrophin 1
chr4_+_158142750 6.79 ENST00000505888.1
ENST00000449365.1
glutamate receptor, ionotropic, AMPA 2
chr11_+_61717279 6.79 ENST00000378043.4
bestrophin 1
chr8_+_133931648 6.77 ENST00000519178.1
ENST00000542445.1
thyroglobulin
chr9_-_130487143 6.76 ENST00000419060.1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chrX_+_2746818 6.71 ENST00000398806.3
glycogenin 2
chr11_+_27062502 6.68 ENST00000263182.3
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr12_+_50355647 6.66 ENST00000293599.6
aquaporin 5
chr19_+_11651942 6.60 ENST00000587087.1
calponin 1, basic, smooth muscle
chr3_-_50340996 6.58 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
hyaluronoglucosaminidase 1
chr14_-_76447494 6.44 ENST00000238682.3
transforming growth factor, beta 3
chr19_+_4304632 6.41 ENST00000597590.1
fibronectin type III and SPRY domain containing 1
chr19_-_15087839 6.29 ENST00000600144.1
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr15_-_65503801 6.21 ENST00000261883.4
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr8_-_21988558 6.20 ENST00000312841.8
hair growth associated
chr9_+_470288 5.92 ENST00000382303.1
KN motif and ankyrin repeat domains 1
chr7_+_143078652 5.88 ENST00000354434.4
ENST00000449423.2
zyxin
chr19_+_4007644 5.85 ENST00000262971.2
protein inhibitor of activated STAT, 4
chr19_+_50380682 5.85 ENST00000221543.5
TBC1 domain family, member 17
chr17_-_34329084 5.82 ENST00000354059.4
ENST00000536149.1
chemokine (C-C motif) ligand 15
chemokine (C-C motif) ligand 14
chr2_+_66662690 5.80 ENST00000488550.1
Meis homeobox 1
chr3_+_9791731 5.75 ENST00000449570.2
ENST00000302008.8
ENST00000383826.5
8-oxoguanine DNA glycosylase
chr16_-_20367584 5.69 ENST00000570689.1
uromodulin
chr12_+_109273806 5.63 ENST00000228476.3
ENST00000547768.1
D-amino-acid oxidase
chr1_-_32169761 5.60 ENST00000271069.6
collagen, type XVI, alpha 1
chr1_-_151345159 5.59 ENST00000458566.1
ENST00000447402.3
ENST00000426705.2
ENST00000435071.1
ENST00000368868.5
selenium binding protein 1
chr5_-_114880533 5.50 ENST00000274457.3
fem-1 homolog c (C. elegans)
chr3_-_10547333 5.49 ENST00000383800.4
ATPase, Ca++ transporting, plasma membrane 2
chr11_-_62457371 5.48 ENST00000317449.4
LRRN4 C-terminal like
chr1_-_32169920 5.47 ENST00000373672.3
ENST00000373668.3
collagen, type XVI, alpha 1
chr17_+_48503603 5.43 ENST00000502667.1
acyl-CoA synthetase family member 2
chrX_+_2746850 5.42 ENST00000381163.3
ENST00000338623.5
ENST00000542787.1
glycogenin 2
chr8_+_98881268 5.36 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
matrilin 2
chr15_-_93199069 5.35 ENST00000327355.5
family with sequence similarity 174, member B
chr17_+_27369918 5.34 ENST00000323372.4
pipecolic acid oxidase
chr19_+_496454 5.32 ENST00000346144.4
ENST00000215637.3
ENST00000382683.4
mucosal vascular addressin cell adhesion molecule 1
chr8_+_120428546 5.30 ENST00000259526.3
nephroblastoma overexpressed
chr15_-_77363375 5.26 ENST00000559494.1
tetraspanin 3
chr2_+_66662510 5.25 ENST00000272369.9
ENST00000407092.2
Meis homeobox 1
chr4_+_144303093 5.21 ENST00000505913.1
GRB2-associated binding protein 1
chr22_+_26565440 5.14 ENST00000404234.3
ENST00000529632.2
ENST00000360929.3
ENST00000248933.6
ENST00000343706.4
seizure related 6 homolog (mouse)-like
chr10_+_88718314 5.14 ENST00000348795.4
synuclein, gamma (breast cancer-specific protein 1)
chr7_+_75931861 5.07 ENST00000248553.6
heat shock 27kDa protein 1
chr19_+_17326521 5.07 ENST00000593597.1
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr19_+_42788172 5.03 ENST00000160740.3
capicua transcriptional repressor
chr8_+_22022653 5.03 ENST00000354870.5
ENST00000397816.3
ENST00000306349.8
bone morphogenetic protein 1
chr7_-_45128472 4.85 ENST00000490531.2
NAC alpha domain containing
chr10_+_124320156 4.82 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
deleted in malignant brain tumors 1
chr7_+_128470431 4.81 ENST00000325888.8
ENST00000346177.6
filamin C, gamma
chr19_-_33716750 4.81 ENST00000253188.4
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10
chr11_+_61717535 4.76 ENST00000534553.1
ENST00000301774.9
bestrophin 1
chr17_+_48503519 4.74 ENST00000300441.4
ENST00000541920.1
ENST00000506582.1
ENST00000504392.1
ENST00000427954.2
acyl-CoA synthetase family member 2
chr1_+_202995611 4.74 ENST00000367240.2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr9_-_77567743 4.67 ENST00000376854.5
chromosome 9 open reading frame 40
chr5_+_113697983 4.64 ENST00000264773.3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr22_+_17082732 4.59 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
transmembrane phosphatase with tensin homology pseudogene 1
chr8_+_38243821 4.56 ENST00000519476.2
leucine zipper-EF-hand containing transmembrane protein 2
chr11_+_74862032 4.53 ENST00000289575.5
ENST00000341411.4
solute carrier organic anion transporter family, member 2B1
chr1_-_160040038 4.50 ENST00000368089.3
potassium inwardly-rectifying channel, subfamily J, member 10
chr6_-_39197226 4.45 ENST00000359534.3
potassium channel, subfamily K, member 5
chr18_+_33877654 4.45 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
formin homology 2 domain containing 3
chr15_+_75105057 4.44 ENST00000309664.5
ENST00000562810.1
lectin, mannose-binding, 1 like
chr9_+_27109133 4.31 ENST00000519097.1
ENST00000380036.4
TEK tyrosine kinase, endothelial
chr4_-_110723134 4.31 ENST00000510800.1
ENST00000512148.1
complement factor I
chr18_-_52989525 4.25 ENST00000457482.3
transcription factor 4
chr13_-_96705624 4.23 ENST00000376747.3
ENST00000376712.4
ENST00000397618.3
ENST00000376714.3
UDP-glucose glycoprotein glucosyltransferase 2
chr6_+_28317685 4.22 ENST00000252211.2
ENST00000341464.5
ENST00000377255.3
zinc finger with KRAB and SCAN domains 3
chr10_+_124320195 4.22 ENST00000359586.6
deleted in malignant brain tumors 1
chr15_-_77363441 4.17 ENST00000346495.2
ENST00000424443.3
ENST00000561277.1
tetraspanin 3
chr5_+_140855495 4.11 ENST00000308177.3
protocadherin gamma subfamily C, 3
chr1_+_203595689 4.09 ENST00000357681.5
ATPase, Ca++ transporting, plasma membrane 4
chr19_-_42927251 4.02 ENST00000597001.1
lipase, hormone-sensitive

Network of associatons between targets according to the STRING database.

First level regulatory network of TLX1_NFIC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
27.6 165.8 GO:0061518 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
15.2 76.2 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
9.9 29.6 GO:0033693 neurofilament bundle assembly(GO:0033693)
9.2 165.2 GO:0007021 tubulin complex assembly(GO:0007021)
8.9 44.4 GO:1903974 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
7.9 23.8 GO:0031049 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
7.1 21.3 GO:0001300 chronological cell aging(GO:0001300)
6.6 26.5 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
6.3 37.7 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
6.3 18.8 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
5.9 23.7 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
5.8 17.3 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
5.1 15.2 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
4.7 70.9 GO:0015671 oxygen transport(GO:0015671)
4.5 22.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
4.4 13.1 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
3.9 11.8 GO:1904647 response to rotenone(GO:1904647)
3.6 7.2 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
3.6 10.8 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
3.6 10.8 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
3.6 24.9 GO:0009407 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
3.3 16.6 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
3.3 9.9 GO:0060018 astrocyte fate commitment(GO:0060018)
3.1 12.4 GO:0006114 glycerol biosynthetic process(GO:0006114)
3.0 39.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
3.0 27.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
3.0 53.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
2.9 5.8 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
2.7 5.3 GO:1990523 bone regeneration(GO:1990523)
2.6 7.7 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
2.4 24.4 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
2.4 4.8 GO:0042940 D-amino acid transport(GO:0042940)
2.3 6.9 GO:1903248 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
2.2 6.6 GO:1900104 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
2.2 6.5 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
2.1 8.2 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
2.0 53.7 GO:0031639 plasminogen activation(GO:0031639)
2.0 5.9 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
1.9 27.1 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
1.9 11.5 GO:1900034 regulation of cellular response to heat(GO:1900034)
1.9 5.6 GO:0009080 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080)
1.8 9.0 GO:0043152 induction of bacterial agglutination(GO:0043152)
1.8 5.3 GO:0046440 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
1.7 8.5 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
1.6 6.4 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936) frontal suture morphogenesis(GO:0060364) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
1.6 24.1 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
1.5 25.8 GO:0010935 regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907)
1.5 17.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
1.4 9.9 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
1.4 18.4 GO:0030321 transepithelial chloride transport(GO:0030321)
1.4 4.2 GO:0097359 UDP-glucosylation(GO:0097359)
1.4 12.6 GO:0098712 L-glutamate import across plasma membrane(GO:0098712)
1.4 19.3 GO:0001542 ovulation from ovarian follicle(GO:0001542)
1.4 9.5 GO:0042126 nitrate metabolic process(GO:0042126)
1.3 6.7 GO:0015669 gas transport(GO:0015669)
1.3 3.9 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
1.3 5.1 GO:0099640 axo-dendritic protein transport(GO:0099640)
1.3 8.8 GO:0045007 depurination(GO:0045007)
1.2 8.4 GO:2000795 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.2 3.5 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
1.2 14.1 GO:0015074 DNA integration(GO:0015074)
1.1 5.7 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
1.1 3.3 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
1.1 10.6 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
1.0 4.0 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
1.0 6.9 GO:1905146 lysosomal protein catabolic process(GO:1905146)
1.0 5.9 GO:0090131 mesenchyme migration(GO:0090131)
0.9 10.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.9 10.3 GO:0099563 modification of synaptic structure(GO:0099563)
0.8 6.8 GO:0015705 iodide transport(GO:0015705)
0.8 14.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.8 9.5 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.8 2.3 GO:1904640 response to methionine(GO:1904640)
0.8 3.8 GO:0048539 bone marrow development(GO:0048539)
0.7 4.5 GO:1990123 L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
0.7 12.4 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.7 2.1 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.7 2.1 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.7 11.1 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.7 3.4 GO:0001661 conditioned taste aversion(GO:0001661)
0.7 2.0 GO:0046521 sphingoid catabolic process(GO:0046521)
0.6 1.9 GO:0055073 cadmium ion homeostasis(GO:0055073)
0.6 4.3 GO:0048014 Tie signaling pathway(GO:0048014)
0.6 8.4 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.6 4.6 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.6 11.0 GO:0032060 bleb assembly(GO:0032060)
0.5 4.4 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.5 5.3 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.5 4.2 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.5 12.1 GO:0060134 prepulse inhibition(GO:0060134)
0.5 9.3 GO:0035966 response to topologically incorrect protein(GO:0035966)
0.5 10.2 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.5 5.5 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.5 2.0 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.5 37.7 GO:0030574 collagen catabolic process(GO:0030574)
0.5 9.9 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.5 2.3 GO:0099612 protein localization to axon(GO:0099612)
0.4 0.9 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.4 1.3 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.4 10.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.4 1.7 GO:0035995 detection of muscle stretch(GO:0035995)
0.4 6.9 GO:0071285 cellular response to lithium ion(GO:0071285)
0.4 15.2 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.4 11.0 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.4 8.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.4 1.6 GO:0090678 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.4 2.8 GO:0048241 epinephrine transport(GO:0048241)
0.4 28.4 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.4 11.1 GO:0033622 integrin activation(GO:0033622)
0.4 6.6 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.4 12.2 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.4 10.4 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.4 1.8 GO:0051182 coenzyme transport(GO:0051182)
0.3 10.8 GO:0007160 cell-matrix adhesion(GO:0007160)
0.3 1.7 GO:0022614 membrane to membrane docking(GO:0022614)
0.3 14.8 GO:0007618 mating(GO:0007618)
0.3 2.7 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.3 2.7 GO:0006013 mannose metabolic process(GO:0006013)
0.3 3.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.3 13.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.3 2.2 GO:0010454 negative regulation of cell fate commitment(GO:0010454)
0.3 2.4 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.3 3.3 GO:0051873 killing by host of symbiont cells(GO:0051873)
0.3 5.1 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.3 8.4 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.3 4.4 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.3 6.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.3 1.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.3 4.4 GO:0071850 mitotic spindle midzone assembly(GO:0051256) mitotic cell cycle arrest(GO:0071850)
0.3 0.8 GO:0072092 olfactory bulb mitral cell layer development(GO:0061034) ureteric bud invasion(GO:0072092)
0.3 1.7 GO:0060523 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.3 10.7 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.3 12.9 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.3 5.2 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.3 1.0 GO:0061107 seminal vesicle development(GO:0061107)
0.3 8.3 GO:0043030 regulation of macrophage activation(GO:0043030)
0.2 0.7 GO:0019605 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.2 2.7 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.2 0.9 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.2 8.5 GO:0005980 glycogen catabolic process(GO:0005980)
0.2 5.1 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.2 8.0 GO:0048512 circadian behavior(GO:0048512)
0.2 0.6 GO:1902617 response to fluoride(GO:1902617)
0.2 3.5 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.2 1.6 GO:0007288 sperm axoneme assembly(GO:0007288)
0.2 0.4 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.2 2.0 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 2.4 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.2 4.2 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.2 6.8 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 3.5 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.2 7.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 5.8 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.2 0.5 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.2 54.5 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.2 1.5 GO:0046185 aldehyde catabolic process(GO:0046185)
0.2 4.8 GO:0048747 muscle fiber development(GO:0048747)
0.1 1.6 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1 38.2 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 0.4 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.1 3.6 GO:0035272 exocrine system development(GO:0035272)
0.1 5.4 GO:0031102 neuron projection regeneration(GO:0031102)
0.1 4.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 3.3 GO:0016578 histone deubiquitination(GO:0016578)
0.1 0.8 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.1 10.7 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 2.5 GO:0001502 cartilage condensation(GO:0001502)
0.1 1.1 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 2.8 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 4.7 GO:0014047 glutamate secretion(GO:0014047)
0.1 23.5 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.1 2.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 3.1 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 2.9 GO:0050727 regulation of inflammatory response(GO:0050727)
0.1 5.8 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 8.7 GO:0030449 regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.1 30.2 GO:0001558 regulation of cell growth(GO:0001558)
0.1 1.3 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 0.1 GO:0034163 regulation of toll-like receptor 9 signaling pathway(GO:0034163) positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.1 3.7 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.1 3.4 GO:0030282 bone mineralization(GO:0030282)
0.1 13.4 GO:0048511 rhythmic process(GO:0048511)
0.1 1.1 GO:0007520 myoblast fusion(GO:0007520)
0.1 4.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 0.3 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.5 GO:0019321 pentose metabolic process(GO:0019321)
0.0 1.9 GO:0006875 cellular metal ion homeostasis(GO:0006875)
0.0 0.4 GO:0006702 androgen biosynthetic process(GO:0006702)
0.0 6.7 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 2.5 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.0 1.1 GO:0001764 neuron migration(GO:0001764)
0.0 2.3 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 2.0 GO:0070268 cornification(GO:0070268)
0.0 0.7 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.2 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 2.4 GO:0015031 protein transport(GO:0015031)
0.0 0.1 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
17.7 70.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
12.2 195.4 GO:0097418 neurofibrillary tangle(GO:0097418)
10.9 76.2 GO:0033269 internode region of axon(GO:0033269)
10.3 165.2 GO:0097512 cardiac myofibril(GO:0097512)
7.4 44.4 GO:1990682 CSF1-CSF1R complex(GO:1990682)
7.1 21.3 GO:0072563 endothelial microparticle(GO:0072563)
2.7 37.7 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
2.6 26.2 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
1.9 7.5 GO:0043260 laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
1.8 10.8 GO:0032444 activin responsive factor complex(GO:0032444)
1.4 5.8 GO:0005896 interleukin-6 receptor complex(GO:0005896)
1.4 11.1 GO:0005593 FACIT collagen trimer(GO:0005593)
1.4 6.8 GO:0098843 postsynaptic endocytic zone(GO:0098843)
1.3 18.8 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
1.3 23.8 GO:0071141 SMAD protein complex(GO:0071141)
1.3 6.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
1.2 22.3 GO:0031012 extracellular matrix(GO:0031012)
1.1 16.6 GO:0030478 actin cap(GO:0030478)
1.1 7.7 GO:0097452 GAIT complex(GO:0097452)
1.1 12.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.9 8.5 GO:0005638 lamin filament(GO:0005638)
0.8 16.7 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.8 26.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.7 8.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.7 9.0 GO:0042589 zymogen granule membrane(GO:0042589)
0.7 4.9 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.6 4.4 GO:0060091 kinocilium(GO:0060091)
0.6 1.7 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.6 56.2 GO:0043195 terminal bouton(GO:0043195)
0.5 6.9 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.5 2.6 GO:0042643 actomyosin, actin portion(GO:0042643)
0.5 41.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.4 19.2 GO:1904115 axon cytoplasm(GO:1904115)
0.4 3.4 GO:0035976 AP1 complex(GO:0035976)
0.4 3.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.3 1.0 GO:0097183 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.3 15.5 GO:0008305 integrin complex(GO:0008305)
0.3 22.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.3 34.8 GO:0005604 basement membrane(GO:0005604)
0.3 34.4 GO:0005882 intermediate filament(GO:0005882)
0.3 24.1 GO:0042734 presynaptic membrane(GO:0042734)
0.3 22.5 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.3 6.9 GO:0097228 sperm principal piece(GO:0097228)
0.3 4.7 GO:0048786 presynaptic active zone(GO:0048786)
0.3 19.4 GO:0034707 chloride channel complex(GO:0034707)
0.2 6.3 GO:0030673 axolemma(GO:0030673)
0.2 14.7 GO:0005771 multivesicular body(GO:0005771)
0.2 12.1 GO:0043202 lysosomal lumen(GO:0043202)
0.2 3.3 GO:0000124 SAGA complex(GO:0000124)
0.2 4.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.2 6.6 GO:0098793 presynapse(GO:0098793)
0.2 14.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.2 11.0 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2 5.3 GO:0005921 gap junction(GO:0005921)
0.2 18.4 GO:0044216 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.2 19.1 GO:0005796 Golgi lumen(GO:0005796)
0.2 8.6 GO:0016235 aggresome(GO:0016235)
0.2 3.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 43.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2 2.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.2 6.3 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.2 16.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.2 22.5 GO:0032587 ruffle membrane(GO:0032587)
0.2 2.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 1.7 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 11.0 GO:0005811 lipid particle(GO:0005811)
0.1 29.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 10.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 51.7 GO:0045177 apical part of cell(GO:0045177)
0.1 19.8 GO:0030018 Z disc(GO:0030018)
0.1 11.6 GO:0005814 centriole(GO:0005814)
0.1 47.0 GO:0016607 nuclear speck(GO:0016607)
0.1 2.6 GO:0030315 T-tubule(GO:0030315)
0.1 18.4 GO:0060076 excitatory synapse(GO:0060076)
0.1 0.9 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 2.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 3.6 GO:0008021 synaptic vesicle(GO:0008021)
0.1 5.8 GO:0055037 recycling endosome(GO:0055037)
0.1 9.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 1.9 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 1.9 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 2.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.8 GO:0010369 chromocenter(GO:0010369)
0.0 5.6 GO:0001650 fibrillar center(GO:0001650)
0.0 1.3 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 7.1 GO:0045202 synapse(GO:0045202)
0.0 5.8 GO:0030424 axon(GO:0030424)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.8 GO:0042383 sarcolemma(GO:0042383)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
13.1 52.4 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
8.3 166.7 GO:0051787 misfolded protein binding(GO:0051787)
8.3 24.9 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
7.9 23.8 GO:0035501 MH1 domain binding(GO:0035501)
7.4 44.4 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
6.6 26.5 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
6.4 76.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
6.3 18.8 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
5.9 23.7 GO:0035939 microsatellite binding(GO:0035939)
5.8 178.9 GO:0005212 structural constituent of eye lens(GO:0005212)
5.5 70.9 GO:0005344 oxygen transporter activity(GO:0005344)
4.8 24.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
4.1 12.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
3.8 15.2 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
3.5 38.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
3.1 9.3 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
3.0 12.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
2.8 27.8 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
2.7 10.8 GO:0042954 apolipoprotein receptor activity(GO:0030226) lipoprotein transporter activity(GO:0042954)
2.6 20.8 GO:0001849 complement component C1q binding(GO:0001849)
2.4 9.5 GO:0008940 nitrate reductase activity(GO:0008940)
2.4 37.7 GO:0045499 chemorepellent activity(GO:0045499)
2.3 6.9 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
2.3 6.8 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
2.2 6.6 GO:0050501 hyaluronan synthase activity(GO:0050501)
1.9 7.7 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
1.8 5.3 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
1.7 5.2 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
1.7 5.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
1.7 6.7 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
1.4 9.9 GO:0030368 interleukin-17 receptor activity(GO:0030368)
1.4 4.2 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
1.4 16.6 GO:0045159 myosin II binding(GO:0045159)
1.3 4.0 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
1.3 14.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.3 6.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
1.2 18.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
1.2 5.8 GO:0061665 SUMO ligase activity(GO:0061665)
1.1 6.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
1.1 8.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
1.0 3.0 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
1.0 10.9 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.9 4.6 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.9 6.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.9 5.3 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.9 6.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.9 11.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.8 18.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.7 4.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.7 5.8 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.7 76.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.7 2.8 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.7 41.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.7 18.4 GO:0001848 complement binding(GO:0001848)
0.6 1.9 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.6 1.8 GO:0051185 coenzyme transporter activity(GO:0051185)
0.6 6.8 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.6 10.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.5 2.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.5 5.6 GO:0008430 selenium binding(GO:0008430)
0.5 1.5 GO:0097259 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.5 3.4 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.5 9.3 GO:0031005 filamin binding(GO:0031005)
0.5 10.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.5 7.3 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.5 6.9 GO:0005504 fatty acid binding(GO:0005504)
0.4 10.8 GO:0070410 co-SMAD binding(GO:0070410)
0.4 4.8 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.4 2.1 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.4 52.7 GO:0051219 phosphoprotein binding(GO:0051219)
0.4 2.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.4 3.5 GO:1901612 cardiolipin binding(GO:1901612)
0.4 9.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.4 9.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.3 3.5 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.3 1.7 GO:0071253 connexin binding(GO:0071253)
0.3 2.0 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.3 20.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.3 8.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.3 10.8 GO:0043236 laminin binding(GO:0043236)
0.3 6.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.3 3.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.3 53.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.3 8.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.3 5.7 GO:0019864 IgG binding(GO:0019864)
0.3 5.5 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.3 28.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.3 26.2 GO:0030295 protein kinase activator activity(GO:0030295)
0.3 10.4 GO:0042056 chemoattractant activity(GO:0042056)
0.3 5.3 GO:0005112 Notch binding(GO:0005112)
0.3 11.8 GO:0019894 kinesin binding(GO:0019894)
0.2 1.7 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.2 0.4 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.2 2.7 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.2 0.9 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.2 10.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.2 3.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 21.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 5.2 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.2 4.0 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 4.2 GO:0030506 ankyrin binding(GO:0030506)
0.2 0.5 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 2.0 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.2 7.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 1.6 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 3.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 1.5 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 3.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.8 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 14.8 GO:0005178 integrin binding(GO:0005178)
0.1 14.7 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 2.6 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 14.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 1.1 GO:0008432 JUN kinase binding(GO:0008432)
0.1 7.4 GO:0008013 beta-catenin binding(GO:0008013)
0.1 50.6 GO:0046982 protein heterodimerization activity(GO:0046982)
0.1 13.1 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.1 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 1.6 GO:0005372 water transmembrane transporter activity(GO:0005372)
0.1 6.7 GO:0019838 growth factor binding(GO:0019838)
0.1 1.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 10.7 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 5.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.2 GO:0030553 cGMP binding(GO:0030553) 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.4 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 1.7 GO:0017022 myosin binding(GO:0017022)
0.0 3.7 GO:0005179 hormone activity(GO:0005179)
0.0 4.9 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 5.4 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.6 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 1.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.2 ST STAT3 PATHWAY STAT3 Pathway
1.8 93.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
1.4 70.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
1.3 43.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
1.1 46.6 PID ALK1 PATHWAY ALK1 signaling events
1.1 156.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.9 107.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.8 62.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.8 38.2 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.7 20.0 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.7 8.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.7 15.5 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.7 5.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.6 5.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.5 13.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.5 12.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.4 11.1 NABA COLLAGENS Genes encoding collagen proteins
0.4 60.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3 17.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.3 56.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.3 5.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.3 3.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.3 10.7 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.3 8.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.2 2.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 10.1 PID TNF PATHWAY TNF receptor signaling pathway
0.2 5.8 ST ADRENERGIC Adrenergic Pathway
0.2 1.7 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.2 3.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.2 7.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.2 6.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 5.0 ST GA12 PATHWAY G alpha 12 Pathway
0.2 10.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 4.3 PID SHP2 PATHWAY SHP2 signaling
0.1 31.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 11.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 5.3 PID AURORA B PATHWAY Aurora B signaling
0.1 3.2 PID RHOA PATHWAY RhoA signaling pathway
0.1 1.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 2.8 PID NOTCH PATHWAY Notch signaling pathway
0.1 3.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.1 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.3 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 38.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.3 24.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
1.2 31.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
1.2 179.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
1.0 29.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
1.0 5.1 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
1.0 81.4 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.8 50.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.8 26.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.7 2.8 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.7 21.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.6 11.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.6 11.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.5 6.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.5 25.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.5 10.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.5 28.8 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.5 5.2 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.4 8.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.4 23.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.4 10.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.4 8.4 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.4 5.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.4 17.5 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.3 6.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.3 9.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.3 12.9 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.3 5.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.3 4.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.3 17.4 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.3 2.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.2 4.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.2 3.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 26.3 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.2 11.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 3.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 8.5 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.2 18.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 7.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.2 5.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 12.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 4.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 8.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.9 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 1.6 REACTOM