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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for UAGUGUU

Z-value: 1.22

Activity profile of UAGUGUU motif

Sorted Z-values of UAGUGUU motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_182992545 23.94 ENST00000258341.4
laminin, gamma 1 (formerly LAMB2)
chr1_-_225840747 23.78 ENST00000366843.2
ENST00000366844.3
enabled homolog (Drosophila)
chr20_+_17550489 21.08 ENST00000246069.7
destrin (actin depolymerizing factor)
chr22_-_36236265 20.50 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RNA binding protein, fox-1 homolog (C. elegans) 2
chr3_+_171758344 20.32 ENST00000336824.4
ENST00000423424.1
fibronectin type III domain containing 3B
chr19_-_48894762 18.53 ENST00000600980.1
ENST00000330720.2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr4_+_38869410 17.81 ENST00000358869.2
family with sequence similarity 114, member A1
chr6_+_114178512 17.47 ENST00000368635.4
myristoylated alanine-rich protein kinase C substrate
chr1_-_95392635 17.03 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
calponin 3, acidic
chr2_-_209119831 17.00 ENST00000345146.2
isocitrate dehydrogenase 1 (NADP+), soluble
chr3_+_172468472 16.12 ENST00000232458.5
ENST00000392692.3
epithelial cell transforming sequence 2 oncogene
chr5_+_82767284 15.58 ENST00000265077.3
versican
chr2_-_183903133 14.75 ENST00000361354.4
NCK-associated protein 1
chr13_+_76123883 14.21 ENST00000377595.3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr17_-_62658186 14.13 ENST00000262435.9
SMAD specific E3 ubiquitin protein ligase 2
chr2_-_86790593 13.12 ENST00000263856.4
ENST00000409225.2
charged multivesicular body protein 3
chr9_+_114423615 12.91 ENST00000374293.4
guanine nucleotide binding protein (G protein), gamma 10
chr12_+_102271129 12.77 ENST00000258534.8
DNA-damage regulated autophagy modulator 1
chr6_-_30712313 12.77 ENST00000376377.2
ENST00000259874.5
immediate early response 3
chr5_+_102201430 12.64 ENST00000438793.3
ENST00000346918.2
peptidylglycine alpha-amidating monooxygenase
chr1_-_68299130 12.37 ENST00000370982.3
guanine nucleotide binding protein (G protein), gamma 12
chr3_-_123603137 12.33 ENST00000360304.3
ENST00000359169.1
ENST00000346322.5
ENST00000360772.3
myosin light chain kinase
chr16_+_3070313 12.10 ENST00000326577.4
tumor necrosis factor receptor superfamily, member 12A
chr9_+_110045537 11.86 ENST00000358015.3
RAD23 homolog B (S. cerevisiae)
chr7_-_6523755 11.67 ENST00000436575.1
ENST00000258739.4
diacylglycerol lipase, beta
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr3_+_100428268 11.47 ENST00000240851.4
TRK-fused gene
chr21_-_27542972 11.18 ENST00000346798.3
ENST00000439274.2
ENST00000354192.3
ENST00000348990.5
ENST00000357903.3
ENST00000358918.3
ENST00000359726.3
amyloid beta (A4) precursor protein
chr2_+_46769798 11.08 ENST00000238738.4
ras homolog family member Q
chr12_-_6451235 10.66 ENST00000440083.2
ENST00000162749.2
tumor necrosis factor receptor superfamily, member 1A
chr1_+_7831323 10.57 ENST00000054666.6
vesicle-associated membrane protein 3
chr3_-_57583130 10.54 ENST00000303436.6
ADP-ribosylation factor 4
chr16_-_66785699 10.08 ENST00000258198.2
dynein, cytoplasmic 1, light intermediate chain 2
chr2_-_39664405 9.39 ENST00000341681.5
ENST00000263881.3
mitogen-activated protein kinase kinase kinase kinase 3
chr22_+_33197683 9.11 ENST00000266085.6
TIMP metallopeptidase inhibitor 3
chr11_+_69455855 8.97 ENST00000227507.2
ENST00000536559.1
cyclin D1
chr9_+_114393634 8.55 ENST00000556107.1
ENST00000374294.3
DnaJ (Hsp40) homolog, subfamily C , member 25
DNAJC25-GNG10 readthrough
chr8_+_126442563 8.54 ENST00000311922.3
tribbles pseudokinase 1
chr11_-_65667884 8.27 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOS-like antigen 1
chr8_+_64081118 8.18 ENST00000539294.1
YTH domain family, member 3
chr9_-_14314066 8.18 ENST00000397575.3
nuclear factor I/B
chr5_+_179125907 8.17 ENST00000247461.4
ENST00000452673.2
ENST00000502498.1
ENST00000507307.1
ENST00000513246.1
ENST00000502673.1
ENST00000506654.1
ENST00000512607.2
ENST00000510810.1
calnexin
chr21_-_43346790 8.12 ENST00000329623.7
C2 calcium-dependent domain containing 2
chr16_+_83841448 8.12 ENST00000433866.2
heat shock factor binding protein 1
chr3_+_180630090 8.11 ENST00000357559.4
ENST00000305586.7
fragile X mental retardation, autosomal homolog 1
chr10_+_63661053 7.89 ENST00000279873.7
AT rich interactive domain 5B (MRF1-like)
chr1_-_211752073 7.87 ENST00000367001.4
solute carrier family 30 (zinc transporter), member 1
chr2_-_174830430 7.70 ENST00000310015.6
ENST00000455789.2
Sp3 transcription factor
chr17_-_1303462 7.58 ENST00000573026.1
ENST00000575977.1
ENST00000571732.1
ENST00000264335.8
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
chr3_-_176914238 7.52 ENST00000430069.1
ENST00000428970.1
transducin (beta)-like 1 X-linked receptor 1
chr21_+_34775181 7.39 ENST00000290219.6
interferon gamma receptor 2 (interferon gamma transducer 1)
chr6_-_82462425 7.39 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
family with sequence similarity 46, member A
chr11_+_57520715 7.21 ENST00000524630.1
ENST00000529919.1
ENST00000399039.4
ENST00000533189.1
catenin (cadherin-associated protein), delta 1
chr3_+_187930719 7.11 ENST00000312675.4
LIM domain containing preferred translocation partner in lipoma
chr1_+_93913713 7.01 ENST00000604705.1
ENST00000370253.2
formin binding protein 1-like
chr2_-_242212227 6.74 ENST00000427007.1
ENST00000458564.1
ENST00000452065.1
ENST00000427183.2
ENST00000426343.1
ENST00000422080.1
ENST00000449504.1
ENST00000449864.1
ENST00000391975.1
high density lipoprotein binding protein
chr10_+_88516396 6.72 ENST00000372037.3
bone morphogenetic protein receptor, type IA
chr10_+_75757863 6.54 ENST00000372755.3
ENST00000211998.4
ENST00000417648.2
vinculin
chr5_+_122110691 6.42 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
sorting nexin 2
chr13_+_100153665 6.42 ENST00000376387.4
transmembrane 9 superfamily member 2
chr11_+_34642656 6.17 ENST00000257831.3
ENST00000450654.2
ets homologous factor
chr3_-_160283348 6.16 ENST00000334256.4
karyopherin alpha 4 (importin alpha 3)
chr2_-_61765315 6.11 ENST00000406957.1
ENST00000401558.2
exportin 1 (CRM1 homolog, yeast)
chr8_-_145013711 6.11 ENST00000345136.3
plectin
chrX_-_20284958 6.01 ENST00000379565.3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr1_-_244013384 6.00 ENST00000366539.1
v-akt murine thymoma viral oncogene homolog 3
chr10_-_32345305 5.98 ENST00000302418.4
kinesin family member 5B
chr1_+_25071848 5.78 ENST00000374379.4
chloride intracellular channel 4
chr3_-_195808952 5.73 ENST00000540528.1
ENST00000392396.3
ENST00000535031.1
ENST00000420415.1
transferrin receptor
chr6_+_25279651 5.61 ENST00000329474.6
leucine rich repeat containing 16A
chr5_+_79703823 5.57 ENST00000338008.5
ENST00000510158.1
ENST00000505560.1
zinc finger, FYVE domain containing 16
chr15_+_66161871 5.40 ENST00000569896.1
RAB11A, member RAS oncogene family
chr1_-_231560790 5.38 ENST00000366641.3
egl-9 family hypoxia-inducible factor 1
chr17_+_1733276 5.31 ENST00000254719.5
replication protein A1, 70kDa
chr19_+_54694119 5.24 ENST00000456872.1
ENST00000302937.4
ENST00000429671.2
TSEN34 tRNA splicing endonuclease subunit
chr1_-_57045228 5.18 ENST00000371250.3
phosphatidic acid phosphatase type 2B
chr17_+_26662730 5.11 ENST00000226225.2
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr3_+_41240925 5.08 ENST00000396183.3
ENST00000349496.5
ENST00000453024.1
catenin (cadherin-associated protein), beta 1, 88kDa
chr17_-_1359443 5.02 ENST00000574295.1
ENST00000398970.5
ENST00000300574.2
v-crk avian sarcoma virus CT10 oncogene homolog
chr1_+_78470530 4.98 ENST00000370763.5
DnaJ (Hsp40) homolog, subfamily B, member 4
chr9_+_36190853 4.92 ENST00000433436.2
ENST00000538225.1
ENST00000540080.1
clathrin, light chain A
chr12_+_110719032 4.91 ENST00000395494.2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr6_-_24721054 4.86 ENST00000378119.4
chromosome 6 open reading frame 62
chr16_-_87525651 4.85 ENST00000268616.4
zinc finger, CCHC domain containing 14
chr1_+_215740709 4.73 ENST00000259154.4
potassium channel tetramerization domain containing 3
chr4_+_99916765 4.61 ENST00000296411.6
methionyl aminopeptidase 1
chr2_-_20251744 4.57 ENST00000175091.4
lysosomal protein transmembrane 4 alpha
chr17_-_21117902 4.54 ENST00000317635.5
transmembrane protein 11
chrX_+_146993449 4.52 ENST00000218200.8
ENST00000370471.3
ENST00000370477.1
fragile X mental retardation 1
chr3_-_98620500 4.48 ENST00000326840.6
discoidin, CUB and LCCL domain containing 2
chr12_-_46766577 4.48 ENST00000256689.5
solute carrier family 38, member 2
chr17_-_80606304 4.41 ENST00000392325.4
WD repeat domain 45B
chr16_-_85722530 4.32 ENST00000253462.3
GINS complex subunit 2 (Psf2 homolog)
chr9_-_123964114 4.30 ENST00000373840.4
RAB14, member RAS oncogene family
chr1_+_200708671 4.22 ENST00000358823.2
calmodulin regulated spectrin-associated protein family, member 2
chr9_-_16870704 3.95 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
basonuclin 2
chr17_+_57697216 3.94 ENST00000393043.1
ENST00000269122.3
clathrin, heavy chain (Hc)
chr7_+_129710350 3.91 ENST00000335420.5
ENST00000463413.1
kelch domain containing 10
chr10_+_5726764 3.83 ENST00000328090.5
ENST00000496681.1
family with sequence similarity 208, member B
chr8_-_62627057 3.82 ENST00000519234.1
ENST00000379449.6
ENST00000379454.4
ENST00000518068.1
ENST00000517856.1
ENST00000356457.5
aspartate beta-hydroxylase
chr2_+_46926048 3.76 ENST00000306503.5
suppressor of cytokine signaling 5
chr3_-_33481835 3.74 ENST00000283629.3
upstream binding protein 1 (LBP-1a)
chr5_-_142783175 3.72 ENST00000231509.3
ENST00000394464.2
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr2_+_182756615 3.68 ENST00000431877.2
ENST00000320370.7
sperm specific antigen 2
chr3_+_150126101 3.67 ENST00000361875.3
ENST00000361136.2
TSC22 domain family, member 2
chrX_-_20159934 3.66 ENST00000379593.1
ENST00000379607.5
eukaryotic translation initiation factor 1A, X-linked
chr10_-_61666267 3.65 ENST00000263102.6
coiled-coil domain containing 6
chr19_-_4400415 3.59 ENST00000598564.1
ENST00000417295.2
ENST00000269886.3
SH3-domain GRB2-like 1
chr6_-_16761678 3.53 ENST00000244769.4
ENST00000436367.1
ataxin 1
chr11_-_110167352 3.47 ENST00000533991.1
ENST00000528498.1
ENST00000405097.1
ENST00000528900.1
ENST00000530301.1
ENST00000343115.4
radixin
chr9_+_133454943 3.44 ENST00000319725.9
far upstream element (FUSE) binding protein 3
chr15_+_90931450 3.38 ENST00000268182.5
ENST00000560738.1
ENST00000560418.1
IQ motif containing GTPase activating protein 1
chrX_-_41782249 3.35 ENST00000442742.2
ENST00000421587.2
ENST00000378166.4
ENST00000318588.9
ENST00000361962.4
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr13_-_110959478 3.31 ENST00000543140.1
ENST00000375820.4
collagen, type IV, alpha 1
chr16_-_73082274 3.24 ENST00000268489.5
zinc finger homeobox 3
chr1_+_35734562 3.19 ENST00000314607.6
ENST00000373297.2
zinc finger, MYM-type 4
chr11_+_118477144 3.12 ENST00000361417.2
pleckstrin homology-like domain, family B, member 1
chr3_+_105085734 3.09 ENST00000306107.5
activated leukocyte cell adhesion molecule
chr15_+_90808919 3.08 ENST00000379095.3
neugrin, neurite outgrowth associated
chr3_-_72496035 3.03 ENST00000477973.2
RING1 and YY1 binding protein
chr1_-_243418344 3.02 ENST00000366542.1
centrosomal protein 170kDa
chr10_+_134351319 3.01 ENST00000368594.3
ENST00000368593.3
inositol polyphosphate-5-phosphatase, 40kDa
chr1_-_38325256 2.97 ENST00000373036.4
metal-regulatory transcription factor 1
chr1_+_87170247 2.93 ENST00000370558.4
SH3-domain GRB2-like endophilin B1
chr14_+_55034599 2.91 ENST00000392067.3
ENST00000357634.3
sterile alpha motif domain containing 4A
chr3_+_128968437 2.87 ENST00000314797.6
coatomer protein complex, subunit gamma 1
chr5_+_179159813 2.86 ENST00000292599.3
mastermind-like 1 (Drosophila)
chr17_-_1395954 2.84 ENST00000359786.5
myosin IC
chr7_-_23510086 2.71 ENST00000258729.3
insulin-like growth factor 2 mRNA binding protein 3
chr10_-_99447024 2.71 ENST00000370626.3
arginine vasopressin-induced 1
chr3_-_50396978 2.62 ENST00000266025.3
transmembrane protein 115
chr13_-_77460525 2.60 ENST00000377474.2
ENST00000317765.2
potassium channel tetramerization domain containing 12
chr1_+_65613217 2.57 ENST00000545314.1
adenylate kinase 4
chr12_+_120884222 2.55 ENST00000551765.1
ENST00000229384.5
glutamyl-tRNA(Gln) amidotransferase, subunit C
chr12_-_90049828 2.54 ENST00000261173.2
ENST00000348959.3
ATPase, Ca++ transporting, plasma membrane 1
chr1_+_186798073 2.53 ENST00000367466.3
ENST00000442353.2
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr15_+_85523671 2.53 ENST00000310298.4
ENST00000557957.1
phosphodiesterase 8A
chr4_+_41937131 2.52 ENST00000504986.1
ENST00000508448.1
ENST00000513702.1
ENST00000325094.5
transmembrane protein 33
chr8_+_61429416 2.49 ENST00000262646.7
ENST00000531289.1
RAB2A, member RAS oncogene family
chr1_+_89149905 2.34 ENST00000316005.7
ENST00000370521.3
ENST00000370505.3
protein kinase N2
chr20_+_3451650 2.34 ENST00000262919.5
attractin
chr2_+_191513959 2.27 ENST00000337386.5
ENST00000357215.5
NGFI-A binding protein 1 (EGR1 binding protein 1)
chr1_+_201798269 2.25 ENST00000361565.4
importin 9
chr11_+_64073699 2.24 ENST00000405666.1
ENST00000468670.1
estrogen-related receptor alpha
chr6_-_114292449 2.24 ENST00000519065.1
histone deacetylase 2
chr17_-_60142609 2.23 ENST00000397786.2
mediator complex subunit 13
chr6_-_52441713 2.21 ENST00000182527.3
translocation associated membrane protein 2
chr12_+_67663056 2.21 ENST00000545606.1
cullin-associated and neddylation-dissociated 1
chr7_-_87849340 2.19 ENST00000419179.1
ENST00000265729.2
sorcin
chr14_-_64010046 2.19 ENST00000337537.3
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr12_-_54813229 2.14 ENST00000293379.4
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr5_-_114961858 2.14 ENST00000282382.4
ENST00000456936.3
ENST00000408996.4
TMED7-TICAM2 readthrough
transmembrane emp24 protein transport domain containing 7
toll-like receptor adaptor molecule 2
chr12_+_48516357 2.10 ENST00000549022.1
ENST00000547587.1
ENST00000312352.7
phosphofructokinase, muscle
chr5_-_16936340 2.09 ENST00000507288.1
ENST00000513610.1
myosin X
chr5_-_179780312 2.08 ENST00000253778.8
glutamine-fructose-6-phosphate transaminase 2
chr4_-_139163491 1.92 ENST00000280612.5
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr12_+_120875910 1.89 ENST00000551806.1
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial
chr12_+_111843749 1.88 ENST00000341259.2
SH2B adaptor protein 3
chr6_-_116381918 1.84 ENST00000606080.1
fyn-related kinase
chr17_+_7476136 1.84 ENST00000582169.1
ENST00000578754.1
ENST00000578495.1
ENST00000293831.8
ENST00000380512.5
ENST00000585024.1
ENST00000583802.1
ENST00000577269.1
ENST00000584784.1
ENST00000582746.1
eukaryotic translation initiation factor 4A1
chr3_-_46037299 1.83 ENST00000296137.2
FYVE and coiled-coil domain containing 1
chr17_+_38375574 1.81 ENST00000323571.4
ENST00000585043.1
ENST00000394103.3
ENST00000536600.1
WAS/WASL interacting protein family, member 2
chr21_+_40752170 1.80 ENST00000333781.5
ENST00000541890.1
tryptophan rich basic protein
chr14_+_57735614 1.79 ENST00000261558.3
adaptor-related protein complex 5, mu 1 subunit
chr1_+_32479430 1.77 ENST00000327300.7
ENST00000492989.1
KH domain containing, RNA binding, signal transduction associated 1
chr5_-_156486120 1.76 ENST00000522693.1
hepatitis A virus cellular receptor 1
chr1_-_31538517 1.74 ENST00000440538.2
ENST00000423018.2
ENST00000424085.2
ENST00000426105.2
ENST00000257075.5
ENST00000373747.3
ENST00000525843.1
ENST00000373742.2
pumilio RNA-binding family member 1
chr12_+_49761224 1.73 ENST00000553127.1
ENST00000321898.6
spermatogenesis associated, serine-rich 2
chr15_+_59279851 1.71 ENST00000348370.4
ENST00000434298.1
ENST00000559160.1
ring finger protein 111
chr16_-_4166186 1.66 ENST00000294016.3
adenylate cyclase 9
chr17_+_79650962 1.64 ENST00000329138.4
hepatocyte growth factor-regulated tyrosine kinase substrate
chr2_+_106361333 1.63 ENST00000233154.4
ENST00000451463.2
NCK adaptor protein 2
chr12_-_105630016 1.61 ENST00000258530.3
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr12_-_25102252 1.57 ENST00000261192.7
branched chain amino-acid transaminase 1, cytosolic
chr11_-_65381643 1.51 ENST00000309100.3
ENST00000529839.1
ENST00000526293.1
mitogen-activated protein kinase kinase kinase 11
chr4_-_185747188 1.34 ENST00000507295.1
ENST00000504900.1
ENST00000281455.2
ENST00000454703.2
acyl-CoA synthetase long-chain family member 1
chr14_+_102430855 1.32 ENST00000360184.4
dynein, cytoplasmic 1, heavy chain 1
chr3_-_15901278 1.32 ENST00000399451.2
ankyrin repeat domain 28
chr3_+_101292939 1.26 ENST00000265260.3
ENST00000469941.1
ENST00000296024.5
PEST proteolytic signal containing nuclear protein
chr15_+_91073111 1.18 ENST00000420329.2
CREB regulated transcription coactivator 3
chr16_+_22308717 1.06 ENST00000299853.5
ENST00000564209.1
ENST00000565358.1
ENST00000418581.2
ENST00000564883.1
ENST00000359210.4
ENST00000563024.1
polymerase (RNA) III (DNA directed) polypeptide E (80kD)
chr1_-_93257951 1.06 ENST00000543509.1
ENST00000370331.1
ENST00000540033.1
ecotropic viral integration site 5
chr2_-_165697920 0.98 ENST00000342193.4
ENST00000375458.2
cordon-bleu WH2 repeat protein-like 1
chr14_+_103058948 0.97 ENST00000262241.6
REST corepressor 1
chr9_-_86595503 0.91 ENST00000376281.4
ENST00000376264.2
heterogeneous nuclear ribonucleoprotein K
chr1_-_109506036 0.90 ENST00000369976.1
ENST00000356970.2
ENST00000369971.2
ENST00000415331.1
ENST00000357393.4
chloride channel CLIC-like 1
AKNA domain containing 1
chr4_-_41216619 0.85 ENST00000508676.1
ENST00000506352.1
ENST00000295974.8
amyloid beta (A4) precursor protein-binding, family B, member 2
chr10_-_104474128 0.75 ENST00000260746.5
ADP-ribosylation factor-like 3
chr20_-_17662878 0.73 ENST00000377813.1
ENST00000377807.2
ENST00000360807.4
ENST00000398782.2
ribosome binding protein 1
chr9_-_125590818 0.68 ENST00000259467.4
phosducin-like
chr12_+_56915713 0.67 ENST00000262031.5
ENST00000552247.2
RNA binding motif, single stranded interacting protein 2
chr2_-_145275228 0.67 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
zinc finger E-box binding homeobox 2
chr6_+_163835669 0.65 ENST00000453779.2
ENST00000275262.7
ENST00000392127.2
ENST00000361752.3
QKI, KH domain containing, RNA binding
chrX_-_11445856 0.55 ENST00000380736.1
Rho GTPase activating protein 6
chr9_+_100395891 0.49 ENST00000375147.3
nuclear cap binding protein subunit 1, 80kDa
chr17_-_49198216 0.46 ENST00000262013.7
ENST00000357122.4
sperm associated antigen 9
chr7_-_98741642 0.44 ENST00000361368.2
SMAD specific E3 ubiquitin protein ligase 1
chr16_+_56965960 0.43 ENST00000439977.2
ENST00000344114.4
ENST00000300302.5
ENST00000379792.2
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr12_-_25403737 0.39 ENST00000256078.4
ENST00000556131.1
ENST00000311936.3
ENST00000557334.1
Kirsten rat sarcoma viral oncogene homolog
chr7_-_25019760 0.32 ENST00000352860.1
ENST00000353930.1
ENST00000431825.2
ENST00000313367.2
oxysterol binding protein-like 3
chr21_-_40685477 0.24 ENST00000342449.3
bromodomain and WD repeat domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of UAGUGUU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 17.0 GO:0006097 glyoxylate cycle(GO:0006097)
3.5 14.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
3.4 20.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
3.2 12.6 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
2.8 8.5 GO:0045659 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
2.7 30.2 GO:0006621 protein retention in ER lumen(GO:0006621)
2.5 7.6 GO:1902309 regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
2.3 9.1 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
2.2 6.7 GO:0048382 mesendoderm development(GO:0048382)
2.2 11.2 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
1.9 21.1 GO:0030043 actin filament fragmentation(GO:0030043)
1.7 5.2 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
1.7 5.1 GO:0070602 negative regulation of mitotic cell cycle, embryonic(GO:0045976) regulation of centromeric sister chromatid cohesion(GO:0070602) renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054) positive regulation of determination of dorsal identity(GO:2000017)
1.6 13.1 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
1.6 4.9 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
1.6 27.1 GO:0070831 basement membrane assembly(GO:0070831)
1.6 7.9 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
1.5 12.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
1.5 10.6 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
1.4 14.5 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
1.3 5.4 GO:0010796 regulation of multivesicular body size(GO:0010796)
1.3 7.7 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
1.3 3.8 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
1.3 14.0 GO:0045176 apical protein localization(GO:0045176)
1.3 2.5 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
1.3 7.5 GO:0060613 fat pad development(GO:0060613)
1.2 9.7 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
1.2 6.0 GO:0035617 stress granule disassembly(GO:0035617)
1.2 8.2 GO:2000795 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.0 2.9 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
1.0 10.7 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
1.0 2.9 GO:0060926 atrioventricular node development(GO:0003162) cardiac pacemaker cell differentiation(GO:0060920) cardiac pacemaker cell development(GO:0060926)
0.9 4.5 GO:2000301 regulation of intracellular transport of viral material(GO:1901252) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.9 9.0 GO:0070141 response to UV-A(GO:0070141)
0.9 17.0 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.9 5.4 GO:0033121 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.9 13.3 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.9 6.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.8 17.5 GO:0051764 actin crosslink formation(GO:0051764)
0.8 3.3 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.8 3.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.7 2.2 GO:0061198 fungiform papilla formation(GO:0061198)
0.7 4.3 GO:0032328 alanine transport(GO:0032328)
0.7 5.8 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.7 2.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.6 2.5 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.6 8.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.6 3.8 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.6 15.6 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.6 11.1 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.6 4.0 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.6 5.0 GO:0001878 response to yeast(GO:0001878)
0.6 8.3 GO:0009629 response to gravity(GO:0009629)
0.5 26.9 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.5 2.5 GO:1990034 calcium ion export from cell(GO:1990034)
0.5 7.0 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.5 2.8 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.5 8.9 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.5 3.7 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.5 4.6 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.5 6.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.4 9.8 GO:2000637 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.4 1.8 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.4 1.3 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.4 6.5 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.4 17.2 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
0.4 2.6 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.4 9.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.4 3.3 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.4 3.6 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.4 6.7 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.4 8.8 GO:0061157 mRNA destabilization(GO:0061157)
0.4 1.9 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.4 6.0 GO:0045793 positive regulation of cell size(GO:0045793)
0.4 5.7 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.4 2.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.3 3.4 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.3 3.0 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.3 1.3 GO:0034201 response to oleic acid(GO:0034201)
0.3 7.2 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.3 2.2 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.3 2.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.3 1.8 GO:1901096 regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.3 1.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.3 10.1 GO:0051642 centrosome localization(GO:0051642)
0.3 3.0 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.3 1.6 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.3 6.2 GO:0019054 modulation by virus of host process(GO:0019054)
0.3 1.6 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.3 6.0 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.2 2.2 GO:0010265 SCF complex assembly(GO:0010265)
0.2 0.9 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.2 6.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 2.9 GO:0051683 establishment of Golgi localization(GO:0051683)
0.2 7.4 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.2 4.4 GO:0044804 nucleophagy(GO:0044804)
0.2 4.0 GO:0043586 tongue development(GO:0043586)
0.2 7.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 2.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.2 2.1 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.2 4.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 0.7 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.2 0.7 GO:1902748 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.2 1.0 GO:0070933 histone H4 deacetylation(GO:0070933)
0.2 3.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 3.1 GO:0048846 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.1 1.0 GO:0051639 actin filament network formation(GO:0051639)
0.1 2.6 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 1.7 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 1.9 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 1.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.4 GO:0021896 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
0.1 0.5 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 2.5 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.1 3.7 GO:0035987 endodermal cell differentiation(GO:0035987)
0.1 0.5 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 6.0 GO:0048207 vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 3.6 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 0.4 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1 12.3 GO:2001020 regulation of response to DNA damage stimulus(GO:2001020)
0.1 0.2 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.1 6.9 GO:1900046 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.1 2.3 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 2.2 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1 3.0 GO:0046686 response to cadmium ion(GO:0046686)
0.1 7.9 GO:0001889 liver development(GO:0001889)
0.1 0.2 GO:2000391 positive regulation of neutrophil extravasation(GO:2000391)
0.1 1.7 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.5 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.0 2.3 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 11.8 GO:0007411 axon guidance(GO:0007411)
0.0 2.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 2.3 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.0 9.2 GO:0010506 regulation of autophagy(GO:0010506)
0.0 5.0 GO:0009408 response to heat(GO:0009408)
0.0 4.0 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 1.1 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 2.7 GO:0017148 negative regulation of translation(GO:0017148)
0.0 8.7 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.8 GO:0042461 photoreceptor cell development(GO:0042461)
0.0 3.7 GO:0006413 translational initiation(GO:0006413)
0.0 1.8 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.2 GO:0003091 renal water homeostasis(GO:0003091)
0.0 0.7 GO:0019079 viral genome replication(GO:0019079)
0.0 3.7 GO:0000226 microtubule cytoskeleton organization(GO:0000226)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
6.0 23.9 GO:0043260 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
3.2 16.1 GO:0097149 centralspindlin complex(GO:0097149)
1.7 15.7 GO:1990812 growth cone filopodium(GO:1990812)
1.7 23.5 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
1.3 5.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
1.1 17.5 GO:0043073 germ cell nucleus(GO:0043073)
1.1 5.4 GO:0098837 postsynaptic recycling endosome(GO:0098837)
1.1 4.3 GO:0000811 GINS complex(GO:0000811)
1.1 6.4 GO:0030905 retromer, tubulation complex(GO:0030905)
1.1 14.7 GO:0031209 SCAR complex(GO:0031209)
1.0 5.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
1.0 13.1 GO:0000815 ESCRT III complex(GO:0000815)
1.0 8.9 GO:0071439 clathrin complex(GO:0071439)
1.0 12.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.7 8.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.7 2.8 GO:0045160 myosin I complex(GO:0045160)
0.7 3.5 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.7 11.9 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.7 8.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.7 6.0 GO:0035253 ciliary rootlet(GO:0035253)
0.6 3.8 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.6 33.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.6 7.2 GO:0005915 zonula adherens(GO:0005915)
0.6 6.5 GO:0005916 fascia adherens(GO:0005916)
0.6 2.9 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.5 1.6 GO:0033565 ESCRT-0 complex(GO:0033565)
0.5 2.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.5 6.1 GO:0005642 annulate lamellae(GO:0005642)
0.5 9.1 GO:0031089 platelet dense granule lumen(GO:0031089)
0.4 3.5 GO:0051286 cell tip(GO:0051286)
0.4 3.4 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.4 2.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.4 3.3 GO:0005587 collagen type IV trimer(GO:0005587)
0.4 11.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.4 11.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.4 4.9 GO:0097470 ribbon synapse(GO:0097470)
0.3 2.2 GO:0044326 dendritic spine neck(GO:0044326)
0.3 3.1 GO:0045180 basal cortex(GO:0045180)
0.3 17.0 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3 6.1 GO:0030056 hemidesmosome(GO:0030056)
0.3 4.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.3 8.0 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.2 4.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 26.2 GO:0030175 filopodium(GO:0030175)
0.2 14.7 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 2.6 GO:0017119 Golgi transport complex(GO:0017119)
0.2 20.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.2 8.1 GO:0005856 cytoskeleton(GO:0005856)
0.2 3.4 GO:0005652 nuclear lamina(GO:0005652)
0.2 21.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 10.3 GO:0005801 cis-Golgi network(GO:0005801)
0.2 7.6 GO:0005871 kinesin complex(GO:0005871)
0.2 29.2 GO:0043197 dendritic spine(GO:0043197)
0.2 10.6 GO:0031201 SNARE complex(GO:0031201)
0.2 4.2 GO:1990752 microtubule end(GO:1990752)
0.2 6.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 4.5 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 10.9 GO:0042734 presynaptic membrane(GO:0042734)
0.1 15.6 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.8 GO:0098797 plasma membrane protein complex(GO:0098797)
0.1 0.5 GO:0005846 nuclear cap binding complex(GO:0005846)
0.1 2.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 5.8 GO:0005902 microvillus(GO:0005902)
0.1 3.1 GO:0042101 T cell receptor complex(GO:0042101)
0.1 2.9 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.8 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 4.0 GO:0030315 T-tubule(GO:0030315)
0.1 1.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 10.1 GO:0043204 perikaryon(GO:0043204)
0.1 6.2 GO:0018995 host(GO:0018995) host cell(GO:0043657)
0.1 0.4 GO:1990037 Lewy body core(GO:1990037)
0.1 2.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 9.3 GO:0001726 ruffle(GO:0001726)
0.1 21.4 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 1.9 GO:0002102 podosome(GO:0002102)
0.1 4.5 GO:0042383 sarcolemma(GO:0042383)
0.0 2.8 GO:0031519 PcG protein complex(GO:0031519)
0.0 16.7 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 5.3 GO:0016605 PML body(GO:0016605)
0.0 0.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 2.5 GO:0005811 lipid particle(GO:0005811)
0.0 1.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 5.4 GO:0005938 cell cortex(GO:0005938)
0.0 3.0 GO:0005814 centriole(GO:0005814)
0.0 2.5 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.3 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.8 GO:0035580 specific granule lumen(GO:0035580)
0.0 5.1 GO:0010008 endosome membrane(GO:0010008)
0.0 1.3 GO:0044439 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 0.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 2.2 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.5 GO:0005884 actin filament(GO:0005884)
0.0 2.5 GO:0005819 spindle(GO:0005819)
0.0 0.9 GO:0030027 lamellipodium(GO:0030027)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.6 30.2 GO:0005046 KDEL sequence binding(GO:0005046)
5.7 17.0 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
3.7 11.1 GO:0032427 GBD domain binding(GO:0032427)
3.2 12.6 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
2.5 12.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
2.1 10.7 GO:0043120 tumor necrosis factor binding(GO:0043120)
1.9 5.7 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
1.7 5.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
1.6 8.0 GO:0034046 poly(G) binding(GO:0034046)
1.5 6.0 GO:0099609 microtubule lateral binding(GO:0099609)
1.5 7.4 GO:0004906 interferon-gamma receptor activity(GO:0004906)
1.4 14.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
1.3 6.4 GO:1990460 leptin receptor binding(GO:1990460)
1.1 11.2 GO:0051425 PTB domain binding(GO:0051425)
1.1 7.6 GO:0050815 phosphoserine binding(GO:0050815)
1.0 12.4 GO:0042301 phosphate ion binding(GO:0042301)
1.0 8.1 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.9 11.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.7 3.7 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.7 3.7 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.7 13.1 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.7 17.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.6 2.6 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.6 8.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.6 1.7 GO:0032184 SUMO polymer binding(GO:0032184)
0.6 6.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.5 5.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.5 23.8 GO:0050699 WW domain binding(GO:0050699)
0.5 7.9 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.5 9.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.5 15.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.5 10.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.5 8.5 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.5 2.9 GO:0098821 BMP receptor activity(GO:0098821)
0.5 8.3 GO:0044548 S100 protein binding(GO:0044548)
0.5 8.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.4 5.4 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.4 4.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.4 3.9 GO:0032051 clathrin light chain binding(GO:0032051)
0.4 3.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.4 10.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.4 1.9 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.4 1.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.4 3.0 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.4 9.7 GO:0031489 myosin V binding(GO:0031489)
0.4 5.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.4 9.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 2.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.3 10.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 4.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.3 17.5 GO:0005080 protein kinase C binding(GO:0005080)
0.3 9.0 GO:0070064 proline-rich region binding(GO:0070064)
0.3 2.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.3 11.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.3 28.3 GO:0017048 Rho GTPase binding(GO:0017048)
0.3 23.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.3 4.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.3 1.6 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.3 2.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 2.8 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 2.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.2 6.1 GO:0030506 ankyrin binding(GO:0030506)
0.2 2.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.2 4.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.2 2.6 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.2 6.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 11.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.2 0.7 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2 2.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 2.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 2.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 5.0 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 6.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 2.3 GO:0004697 protein kinase C activity(GO:0004697)
0.1 2.1 GO:0008483 transaminase activity(GO:0008483)
0.1 5.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 34.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 2.3 GO:0000339 RNA cap binding(GO:0000339)
0.1 3.8 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.1 21.7 GO:0051015 actin filament binding(GO:0051015)
0.1 2.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.3 GO:0045503 dynein light chain binding(GO:0045503)
0.1 9.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 2.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 3.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 3.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 1.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 2.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 2.9 GO:0042605 peptide antigen binding(GO:0042605)
0.1 1.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 4.6 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 3.5 GO:0051018 protein kinase A binding(GO:0051018)
0.1 1.7 GO:0030371 translation repressor activity(GO:0030371)
0.1 2.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.1 3.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 2.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 1.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 2.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 5.0 GO:0051087 chaperone binding(GO:0051087)
0.0 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 1.1 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 14.9 GO:0045296 cadherin binding(GO:0045296)
0.0 3.1 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 11.1 GO:0003924 GTPase activity(GO:0003924)
0.0 0.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.7 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.4 GO:0032452 histone demethylase activity(GO:0032452)
0.0 1.8 GO:0001618 virus receptor activity(GO:0001618)
0.0 1.8 GO:0005496 steroid binding(GO:0005496)
0.0 0.2 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 1.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 19.0 GO:0003723 RNA binding(GO:0003723)
0.0 2.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 23.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
1.0 68.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.7 17.4 PID ARF 3PATHWAY Arf1 pathway
0.5 15.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.5 18.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.5 17.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.4 16.8 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.4 25.7 PID BMP PATHWAY BMP receptor signaling
0.3 5.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.3 13.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.3 17.6 SIG CHEMOTAXIS Genes related to chemotaxis
0.3 16.1 PID PLK1 PATHWAY PLK1 signaling events
0.2 6.0 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.2 10.1 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.2 12.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.2 8.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.2 9.4 PID TNF PATHWAY TNF receptor signaling pathway
0.1 4.6 PID RHOA PATHWAY RhoA signaling pathway
0.1 7.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 5.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 6.4 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 5.2 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 3.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 9.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 5.3 PID ATR PATHWAY ATR signaling pathway
0.1 2.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 4.2 PID ENDOTHELIN PATHWAY Endothelins
0.1 3.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 7.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 1.9 PID EPO PATHWAY EPO signaling pathway
0.1 2.3 PID IL1 PATHWAY IL1-mediated signaling events
0.1 1.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 6.7 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.1 5.8 PID CMYB PATHWAY C-MYB transcription factor network
0.1 2.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 2.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 5.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 2.8 PID E2F PATHWAY E2F transcription factor network
0.0 9.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 17.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
1.3 25.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.7 6.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.6 17.2 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.6 14.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.6 11.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.6 15.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.5 21.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.5 11.8 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.5 17.0 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.5 8.9 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.5 7.9 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.4 6.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.4 19.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.4 12.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.4 10.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.3 7.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.3 18.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 9.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.3 21.1 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.3 2.5 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.3 25.3 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.3 9.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.3 6.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.3 4.9 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.3 11.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.3 5.4 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.3 4.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.3 5.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.3 6.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 6.0 REACTOME KINESINS Genes involved in Kinesins
0.2 1.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 3.4 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.2 6.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 2.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.2 5.7 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.2 4.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.2 3.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2 7.3 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.2 5.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 2.1 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 11.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 2.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 11.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 5.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 8.0 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 2.2 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 1.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 3.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 3.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 2.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 3.1 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 2.5 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse