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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for UCACAGU

Z-value: 0.62

Motif logo

miRNA associated with seed UCACAGU

NamemiRBASE accession
MIMAT0000084
MIMAT0000419

Activity profile of UCACAGU motif

Sorted Z-values of UCACAGU motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_64708615 15.23 ENST00000338957.4
ENST00000423889.3
zinc finger CCCH-type containing 12B
chr20_+_10199468 11.04 ENST00000254976.2
ENST00000304886.2
synaptosomal-associated protein, 25kDa
chr10_-_21786179 9.38 ENST00000377113.5
cancer susceptibility candidate 10
chr16_-_4292071 7.37 ENST00000399609.3
sarcalumenin
chr8_+_80523321 7.34 ENST00000518111.1
stathmin-like 2
chr16_-_70719925 6.73 ENST00000338779.6
metastasis suppressor 1-like
chr12_-_105478339 6.61 ENST00000424857.2
ENST00000258494.9
aldehyde dehydrogenase 1 family, member L2
chr12_+_79258547 6.13 ENST00000457153.2
synaptotagmin I
chr2_-_100939195 6.07 ENST00000393437.3
LON peptidase N-terminal domain and ring finger 2
chr10_+_104474207 6.02 ENST00000602831.1
ENST00000369893.5
sideroflexin 2
chrX_-_54384425 5.32 ENST00000375169.3
ENST00000354646.2
WNK lysine deficient protein kinase 3
chr5_+_71403061 5.06 ENST00000512974.1
ENST00000296755.7
microtubule-associated protein 1B
chr6_-_46293378 5.05 ENST00000330430.6
regulator of calcineurin 2
chr17_+_43971643 5.05 ENST00000344290.5
ENST00000262410.5
ENST00000351559.5
ENST00000340799.5
ENST00000535772.1
ENST00000347967.5
microtubule-associated protein tau
chr5_-_115910630 4.67 ENST00000343348.6
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr2_-_71454185 4.57 ENST00000244221.8
poly(A) binding protein interacting protein 2B
chr4_-_153457197 4.34 ENST00000281708.4
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr2_+_242641442 4.29 ENST00000313552.6
ENST00000406941.1
inhibitor of growth family, member 5
chr14_-_81687197 4.25 ENST00000553612.1
general transcription factor IIA, 1, 19/37kDa
chr6_-_119399895 4.24 ENST00000338891.7
family with sequence similarity 184, member A
chr17_+_30813576 4.11 ENST00000313401.3
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr3_+_11034403 4.11 ENST00000287766.4
ENST00000425938.1
solute carrier family 6 (neurotransmitter transporter), member 1
chr7_-_103629963 4.09 ENST00000428762.1
ENST00000343529.5
ENST00000424685.2
reelin
chr3_-_179169330 4.05 ENST00000232564.3
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr15_+_29131103 4.05 ENST00000558402.1
ENST00000558330.1
amyloid beta (A4) precursor protein-binding, family A, member 2
chr22_-_39239987 3.91 ENST00000333039.2
neuronal pentraxin receptor
chr10_-_124768300 3.88 ENST00000368886.5
IKAROS family zinc finger 5 (Pegasus)
chr6_+_126112001 3.86 ENST00000392477.2
nuclear receptor coactivator 7
chr19_+_7968728 3.84 ENST00000397981.3
ENST00000545011.1
ENST00000397983.3
ENST00000397979.3
mitogen-activated protein kinase kinase 7
chrX_-_67653614 3.79 ENST00000355520.5
oligophrenin 1
chr16_-_75498553 3.76 ENST00000569276.1
ENST00000357613.4
ENST00000561878.1
ENST00000566980.1
ENST00000567194.1
transmembrane protein 170A
Uncharacterized protein
chr11_-_123525289 3.75 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
sodium channel, voltage-gated, type III, beta subunit
chr20_+_34700333 3.61 ENST00000441639.1
erythrocyte membrane protein band 4.1-like 1
chr5_-_111754948 3.56 ENST00000261486.5
erythrocyte membrane protein band 4.1 like 4A
chr12_-_42538657 3.50 ENST00000398675.3
glucoside xylosyltransferase 1
chr11_-_18656028 3.48 ENST00000336349.5
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr8_+_1922024 3.47 ENST00000320248.3
kelch repeat and BTB (POZ) domain containing 11
chr2_-_206950781 3.45 ENST00000403263.1
INO80 complex subunit D
chr5_-_93447333 3.45 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
family with sequence similarity 172, member A
chr4_+_113970772 3.35 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ankyrin 2, neuronal
chrX_-_40594755 3.31 ENST00000324817.1
mediator complex subunit 14
chr2_-_37193606 3.31 ENST00000379213.2
ENST00000263918.4
striatin, calmodulin binding protein
chr22_-_44258360 3.25 ENST00000330884.4
ENST00000249130.5
sulfotransferase family 4A, member 1
chr5_-_179780312 3.25 ENST00000253778.8
glutamine-fructose-6-phosphate transaminase 2
chr16_+_1756162 3.23 ENST00000250894.4
ENST00000356010.5
mitogen-activated protein kinase 8 interacting protein 3
chr7_+_77325738 3.18 ENST00000334955.8
round spermatid basic protein 1-like
chr19_-_49576198 3.17 ENST00000221444.1
potassium voltage-gated channel, shaker-related subfamily, member 7
chr22_-_28197486 3.12 ENST00000302326.4
meningioma (disrupted in balanced translocation) 1
chrX_+_23352133 3.12 ENST00000379361.4
patched domain containing 1
chr1_-_200992827 3.10 ENST00000332129.2
ENST00000422435.2
kinesin family member 21B
chr19_+_18794470 3.05 ENST00000321949.8
ENST00000338797.6
CREB regulated transcription coactivator 1
chr10_-_62149433 2.96 ENST00000280772.2
ankyrin 3, node of Ranvier (ankyrin G)
chr3_-_56502375 2.95 ENST00000288221.6
ELKS/RAB6-interacting/CAST family member 2
chr2_+_24163281 2.94 ENST00000309033.4
UBX domain protein 2A
chr11_-_108369101 2.94 ENST00000323468.5
KDEL (Lys-Asp-Glu-Leu) containing 2
chrX_+_56259316 2.89 ENST00000468660.1
Kruppel-like factor 8
chr11_+_14665263 2.89 ENST00000282096.4
phosphodiesterase 3B, cGMP-inhibited
chr11_+_118401706 2.86 ENST00000411589.2
ENST00000442938.2
ENST00000359862.4
transmembrane protein 25
chr4_+_85504075 2.86 ENST00000295887.5
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr14_-_100070363 2.85 ENST00000380243.4
coiled-coil domain containing 85C
chr12_-_124457371 2.83 ENST00000238156.3
ENST00000545037.1
coiled-coil domain containing 92
chr12_+_4918342 2.82 ENST00000280684.3
ENST00000433855.1
potassium voltage-gated channel, shaker-related subfamily, member 6
chr4_-_53525406 2.82 ENST00000451218.2
ENST00000441222.3
ubiquitin specific peptidase 46
chr7_-_31380502 2.78 ENST00000297142.3
neuronal differentiation 6
chr2_-_50574856 2.75 ENST00000342183.5
neurexin 1
chr2_-_201936302 2.74 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
family with sequence similarity 126, member B
chr5_+_112043186 2.74 ENST00000509732.1
ENST00000457016.1
ENST00000507379.1
adenomatous polyposis coli
chr9_-_91793675 2.71 ENST00000375835.4
ENST00000375830.1
SHC (Src homology 2 domain containing) transforming protein 3
chr5_+_65018017 2.68 ENST00000380985.5
ENST00000502464.1
neurolysin (metallopeptidase M3 family)
chr12_-_49110613 2.61 ENST00000261900.3
cyclin T1
chr3_-_178790057 2.60 ENST00000311417.2
zinc finger, matrin-type 3
chr13_-_67804445 2.60 ENST00000456367.1
ENST00000377861.3
ENST00000544246.1
protocadherin 9
chr8_-_98290087 2.45 ENST00000322128.3
TSPY-like 5
chr11_-_117186946 2.44 ENST00000313005.6
ENST00000528053.1
beta-site APP-cleaving enzyme 1
chr1_-_149889382 2.44 ENST00000369145.1
ENST00000369146.3
synaptic vesicle glycoprotein 2A
chr11_-_45687128 2.44 ENST00000308064.2
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr3_+_36421826 2.41 ENST00000273183.3
SH3 and cysteine rich domain
chr12_+_8234807 2.40 ENST00000339754.5
NECAP endocytosis associated 1
chr10_+_60272814 2.39 ENST00000373886.3
bicaudal C homolog 1 (Drosophila)
chr8_-_10588010 2.39 ENST00000304501.1
SRY (sex determining region Y)-box 7
chr20_+_49348081 2.38 ENST00000371610.2
par-6 family cell polarity regulator beta
chrX_+_122993827 2.33 ENST00000371199.3
X-linked inhibitor of apoptosis
chr11_-_74109422 2.33 ENST00000298198.4
phosphoglucomutase 2-like 1
chr5_-_132073210 2.31 ENST00000378735.1
ENST00000378746.4
kinesin family member 3A
chr18_+_54318616 2.30 ENST00000254442.3
WD repeat domain 7
chr6_+_30524663 2.29 ENST00000376560.3
proline rich 3
chr9_-_136857403 2.28 ENST00000406606.3
ENST00000371850.3
vav 2 guanine nucleotide exchange factor
chr6_-_99873145 2.27 ENST00000369239.5
ENST00000438806.1
PNN-interacting serine/arginine-rich protein
chr9_-_23821273 2.24 ENST00000380110.4
ELAV like neuron-specific RNA binding protein 2
chr2_+_203879568 2.21 ENST00000449802.1
neurobeachin-like 1
chr11_+_121322832 2.20 ENST00000260197.7
sortilin-related receptor, L(DLR class) A repeats containing
chr5_+_172483347 2.19 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
CREB3 regulatory factor
chr17_+_25799008 2.16 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
kinase suppressor of ras 1
chr20_-_41818373 2.14 ENST00000373187.1
ENST00000356100.2
ENST00000373184.1
ENST00000373190.1
protein tyrosine phosphatase, receptor type, T
chr17_-_58603568 2.14 ENST00000083182.3
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr16_-_68482440 2.13 ENST00000219334.5
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr5_-_57756087 2.12 ENST00000274289.3
polo-like kinase 2
chr1_-_160001737 2.11 ENST00000368090.2
phosphatidylinositol glycan anchor biosynthesis, class M
chr3_+_139654018 2.11 ENST00000458420.3
calsyntenin 2
chr21_+_33245548 2.08 ENST00000270112.2
hormonally up-regulated Neu-associated kinase
chr14_+_99947715 2.06 ENST00000389879.5
ENST00000557441.1
ENST00000555049.1
ENST00000555842.1
cyclin K
chr16_-_65155833 2.05 ENST00000566827.1
ENST00000394156.3
ENST00000562998.1
cadherin 11, type 2, OB-cadherin (osteoblast)
chr5_-_43313574 2.05 ENST00000325110.6
ENST00000433297.2
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr8_-_94753229 2.05 ENST00000518597.1
ENST00000399300.2
ENST00000517700.1
RNA binding motif protein 12B
chr16_+_23847339 2.05 ENST00000303531.7
protein kinase C, beta
chr4_+_47033345 2.04 ENST00000295454.3
gamma-aminobutyric acid (GABA) A receptor, beta 1
chr1_-_19229248 2.04 ENST00000375341.3
aldehyde dehydrogenase 4 family, member A1
chr1_-_154474589 2.03 ENST00000304760.2
Src homology 2 domain containing E
chr14_+_85996471 2.02 ENST00000330753.4
fibronectin leucine rich transmembrane protein 2
chr20_-_48532019 2.02 ENST00000289431.5
spermatogenesis associated 2
chr7_-_108096822 2.02 ENST00000379028.3
ENST00000413765.2
ENST00000379022.4
neuronal cell adhesion molecule
chr5_-_95297678 2.01 ENST00000237853.4
elongation factor, RNA polymerase II, 2
chr1_+_70876891 2.01 ENST00000411986.2
cystathionase (cystathionine gamma-lyase)
chr10_-_81205373 2.00 ENST00000372336.3
zinc finger, CCHC domain containing 24
chr4_+_140374961 1.99 ENST00000305626.5
RAB33B, member RAS oncogene family
chr3_+_14989076 1.98 ENST00000413118.1
ENST00000425241.1
nuclear receptor subfamily 2, group C, member 2
chr17_+_47572647 1.97 ENST00000172229.3
nerve growth factor receptor
chr7_-_105029329 1.96 ENST00000393651.3
ENST00000460391.1
SRSF protein kinase 2
chr6_-_39197226 1.96 ENST00000359534.3
potassium channel, subfamily K, member 5
chrX_+_16804544 1.95 ENST00000380122.5
ENST00000398155.4
taxilin gamma
chr8_-_127570603 1.95 ENST00000304916.3
family with sequence similarity 84, member B
chr12_-_54673871 1.95 ENST00000209875.4
chromobox homolog 5
chr6_+_41606176 1.94 ENST00000441667.1
ENST00000230321.6
ENST00000373050.4
ENST00000446650.1
ENST00000435476.1
MyoD family inhibitor
chr4_-_90229142 1.92 ENST00000609438.1
GPRIN family member 3
chr10_-_102279586 1.92 ENST00000370345.3
ENST00000451524.1
ENST00000370329.5
SEC31 homolog B (S. cerevisiae)
chr13_+_24734844 1.91 ENST00000382108.3
spermatogenesis associated 13
chr17_+_54911444 1.91 ENST00000284061.3
ENST00000572810.1
diacylglycerol kinase, epsilon 64kDa
chr6_+_391739 1.91 ENST00000380956.4
interferon regulatory factor 4
chr19_+_41222998 1.89 ENST00000263370.2
inositol-trisphosphate 3-kinase C
chr10_+_111767720 1.87 ENST00000356080.4
ENST00000277900.8
adducin 3 (gamma)
chr19_-_16653325 1.86 ENST00000546361.2
calcium homeostasis endoplasmic reticulum protein
chr1_+_184356188 1.82 ENST00000235307.6
chromosome 1 open reading frame 21
chr16_+_11762270 1.82 ENST00000329565.5
stannin
chr20_+_48599506 1.81 ENST00000244050.2
snail family zinc finger 1
chr19_-_13617247 1.81 ENST00000573710.2
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr5_-_132948216 1.79 ENST00000265342.7
follistatin-like 4
chr5_-_132299313 1.79 ENST00000265343.5
AF4/FMR2 family, member 4
chr7_+_90225796 1.79 ENST00000380050.3
cyclin-dependent kinase 14
chr11_-_73309228 1.76 ENST00000356467.4
ENST00000064778.4
family with sequence similarity 168, member A
chr6_+_136172820 1.75 ENST00000308191.6
phosphodiesterase 7B
chr2_+_5832799 1.74 ENST00000322002.3
SRY (sex determining region Y)-box 11
chr11_+_58939965 1.71 ENST00000227451.3
deltex homolog 4 (Drosophila)
chr7_-_79082867 1.70 ENST00000419488.1
ENST00000354212.4
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_-_38303218 1.68 ENST00000407341.1
ENST00000260630.3
cytochrome P450, family 1, subfamily B, polypeptide 1
chr10_-_15762124 1.66 ENST00000378076.3
integrin, alpha 8
chr10_+_63661053 1.66 ENST00000279873.7
AT rich interactive domain 5B (MRF1-like)
chr10_+_104678032 1.66 ENST00000369878.4
ENST00000369875.3
cyclin M2
chr1_+_220701456 1.66 ENST00000366918.4
ENST00000402574.1
MAP/microtubule affinity-regulating kinase 1
chr2_-_9143786 1.64 ENST00000462696.1
ENST00000305997.3
membrane bound O-acyltransferase domain containing 2
chr4_+_20255123 1.62 ENST00000504154.1
ENST00000273739.5
slit homolog 2 (Drosophila)
chr12_+_70760056 1.60 ENST00000258111.4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr9_+_103790991 1.60 ENST00000374874.3
Lipid phosphate phosphatase-related protein type 1
chr12_+_103981044 1.60 ENST00000388887.2
stabilin 2
chr9_-_135819987 1.57 ENST00000298552.3
ENST00000403810.1
tuberous sclerosis 1
chr9_+_34958254 1.57 ENST00000242315.3
KIAA1045
chr6_-_8064567 1.56 ENST00000543936.1
ENST00000397457.2
biogenesis of lysosomal organelles complex-1, subunit 5, muted
chr10_-_119806085 1.55 ENST00000355624.3
RAB11 family interacting protein 2 (class I)
chr10_-_90712520 1.54 ENST00000224784.6
actin, alpha 2, smooth muscle, aorta
chr19_+_1286097 1.52 ENST00000215368.2
ephrin-A2
chr10_-_70287231 1.52 ENST00000609923.1
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr1_+_65613217 1.52 ENST00000545314.1
adenylate kinase 4
chr11_-_31839488 1.51 ENST00000419022.1
ENST00000379132.3
ENST00000379129.2
paired box 6
chr2_+_46524537 1.51 ENST00000263734.3
endothelial PAS domain protein 1
chr12_+_132195617 1.49 ENST00000261674.4
ENST00000535236.1
ENST00000541286.1
splicing factor, suppressor of white-apricot homolog (Drosophila)
chr2_-_27718052 1.48 ENST00000264703.3
fibronectin type III domain containing 4
chr5_+_52285144 1.44 ENST00000296585.5
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr1_-_41131326 1.43 ENST00000372684.3
regulating synaptic membrane exocytosis 3
chr5_-_121413974 1.42 ENST00000231004.4
lysyl oxidase
chr11_-_86666427 1.41 ENST00000531380.1
frizzled family receptor 4
chr2_-_25142708 1.39 ENST00000260600.5
ENST00000435135.1
adenylate cyclase 3
chr17_-_53499310 1.39 ENST00000262065.3
monocyte to macrophage differentiation-associated
chr5_-_160279207 1.38 ENST00000327245.5
ATPase, class V, type 10B
chr7_-_27183263 1.38 ENST00000222726.3
homeobox A5
chr17_-_3461092 1.36 ENST00000301365.4
ENST00000572519.1
transient receptor potential cation channel, subfamily V, member 3
chr1_-_36022979 1.34 ENST00000469892.1
ENST00000325722.3
KIAA0319-like
chr15_+_33010175 1.34 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
gremlin 1, DAN family BMP antagonist
chr5_-_111093406 1.33 ENST00000379671.3
neuronal regeneration related protein
chr14_+_56585048 1.32 ENST00000267460.4
pellino E3 ubiquitin protein ligase family member 2
chr1_+_35734562 1.31 ENST00000314607.6
ENST00000373297.2
zinc finger, MYM-type 4
chr4_+_71587669 1.30 ENST00000381006.3
ENST00000226328.4
RUN and FYVE domain containing 3
chr11_+_33278811 1.30 ENST00000303296.4
ENST00000379016.3
homeodomain interacting protein kinase 3
chr8_-_42698433 1.30 ENST00000345117.2
ENST00000254250.3
THAP domain containing, apoptosis associated protein 1
chr1_-_21671968 1.30 ENST00000415912.2
endothelin converting enzyme 1
chr8_-_93115445 1.29 ENST00000523629.1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_+_85097110 1.29 ENST00000517638.1
ENST00000522647.1
RALY RNA binding protein-like
chr10_+_127408263 1.28 ENST00000337623.3
erythroid differentiation regulatory factor 1
chr1_-_184723942 1.28 ENST00000318130.8
ER degradation enhancer, mannosidase alpha-like 3
chr16_+_2587998 1.27 ENST00000441549.3
ENST00000268673.7
3-phosphoinositide dependent protein kinase-1
chr5_+_135468516 1.27 ENST00000507118.1
ENST00000511116.1
ENST00000545279.1
ENST00000545620.1
SMAD family member 5
chrX_+_102631248 1.26 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr1_-_57045228 1.26 ENST00000371250.3
phosphatidic acid phosphatase type 2B
chr6_-_41747595 1.25 ENST00000373018.3
fibroblast growth factor receptor substrate 3
chr17_+_29421900 1.25 ENST00000358273.4
ENST00000356175.3
neurofibromin 1
chr9_+_112403088 1.25 ENST00000448454.2
paralemmin 2
chr16_+_66878814 1.25 ENST00000394069.3
carbonic anhydrase VII
chr15_-_73661605 1.24 ENST00000261917.3
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr3_+_119187785 1.23 ENST00000295588.4
ENST00000476573.1
protein O-glucosyltransferase 1
chr10_-_97321112 1.23 ENST00000607232.1
ENST00000371227.4
ENST00000371249.2
ENST00000371247.2
ENST00000371246.2
ENST00000393949.1
ENST00000353505.5
ENST00000347291.4
sorbin and SH3 domain containing 1
chr4_+_55095264 1.21 ENST00000257290.5
platelet-derived growth factor receptor, alpha polypeptide
chr2_-_235405679 1.21 ENST00000390645.2
ADP-ribosylation factor-like 4C

Network of associatons between targets according to the STRING database.

First level regulatory network of UCACAGU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.6 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
2.0 6.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
1.9 9.7 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
1.8 7.3 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
1.4 4.1 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
1.1 3.4 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.0 4.1 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
1.0 4.1 GO:0097477 NMDA glutamate receptor clustering(GO:0097114) spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
1.0 3.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
1.0 5.0 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
1.0 3.9 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.9 2.7 GO:0098528 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.9 4.3 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.9 2.6 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.8 1.7 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.8 2.3 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.8 3.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.7 3.0 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.7 2.2 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.7 2.2 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.7 2.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.7 2.0 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.6 1.9 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.6 3.1 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.6 1.9 GO:0060023 soft palate development(GO:0060023)
0.6 4.9 GO:0035897 proteolysis in other organism(GO:0035897)
0.6 1.8 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.6 0.6 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.5 1.6 GO:0021966 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) corticospinal neuron axon guidance(GO:0021966) regulation of negative chemotaxis(GO:0050923) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.5 2.6 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.5 2.0 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.5 2.0 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.5 5.0 GO:0086015 SA node cell action potential(GO:0086015) SA node cell to atrial cardiac muscle cell signalling(GO:0086018)
0.5 2.4 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.5 1.4 GO:0008355 olfactory learning(GO:0008355)
0.4 1.3 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.4 0.9 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.4 2.9 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.4 1.2 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.4 0.8 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.4 1.2 GO:0072276 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.4 2.0 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.4 2.0 GO:0035063 nuclear speck organization(GO:0035063)
0.4 1.1 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.4 1.8 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.3 1.0 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.3 2.7 GO:0097118 gephyrin clustering involved in postsynaptic density assembly(GO:0097116) neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.3 2.0 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.3 1.0 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.3 1.3 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.3 2.9 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.3 1.6 GO:0051029 rRNA transport(GO:0051029)
0.3 2.8 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.3 2.8 GO:0008343 adult feeding behavior(GO:0008343)
0.3 2.7 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.3 1.5 GO:0003322 pancreatic A cell development(GO:0003322)
0.3 2.0 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.3 2.6 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.3 1.1 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.3 2.0 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
0.3 1.1 GO:1990535 transformation of host cell by virus(GO:0019087) neuron projection maintenance(GO:1990535)
0.3 0.5 GO:0014042 positive regulation of neuron maturation(GO:0014042)
0.3 1.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.3 1.5 GO:0090131 mesenchyme migration(GO:0090131)
0.3 1.3 GO:0097466 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.3 0.8 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.3 1.5 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.3 4.8 GO:0006012 galactose metabolic process(GO:0006012)
0.2 1.2 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.2 3.9 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 3.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.2 1.0 GO:1902617 response to fluoride(GO:1902617)
0.2 1.4 GO:0001880 Mullerian duct regression(GO:0001880)
0.2 2.1 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.2 5.2 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.2 1.8 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.2 0.4 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.2 2.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 0.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 0.8 GO:0008063 Toll signaling pathway(GO:0008063)
0.2 2.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 0.4 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.2 0.6 GO:0021764 amygdala development(GO:0021764)
0.2 2.0 GO:0050942 positive regulation of pigment cell differentiation(GO:0050942)
0.2 0.4 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) negative regulation of interferon-alpha production(GO:0032687)
0.2 1.4 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.2 1.4 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.2 1.0 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
0.2 2.0 GO:0009642 response to light intensity(GO:0009642)
0.2 2.9 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.2 4.9 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.2 1.6 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.2 1.2 GO:0048318 axial mesoderm development(GO:0048318)
0.2 0.7 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.2 0.8 GO:0042713 sperm ejaculation(GO:0042713)
0.2 1.0 GO:0055064 chloride ion homeostasis(GO:0055064)
0.2 2.0 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.2 1.8 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.2 0.3 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.2 1.8 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.2 0.6 GO:0071321 cellular response to cGMP(GO:0071321)
0.2 0.9 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.2 0.8 GO:0043988 histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
0.2 0.5 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.2 1.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.2 6.7 GO:0097178 ruffle assembly(GO:0097178)
0.2 0.9 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.1 1.0 GO:0046836 glycolipid transport(GO:0046836)
0.1 0.7 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 1.2 GO:0019563 glycerol catabolic process(GO:0019563)
0.1 2.2 GO:0021794 thalamus development(GO:0021794)
0.1 0.9 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 0.4 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.4 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.9 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 1.3 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.9 GO:0044254 angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266)
0.1 0.4 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.1 0.4 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.9 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.1 1.0 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.1 0.6 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.1 0.6 GO:1904141 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) positive regulation of microglial cell migration(GO:1904141)
0.1 4.3 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 2.2 GO:0071420 cellular response to histamine(GO:0071420)
0.1 2.1 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.1 0.2 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.4 GO:0090107 aminophospholipid transport(GO:0015917) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1 0.8 GO:1902915 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.1 3.3 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 2.9 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 2.1 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 1.7 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.9 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 3.6 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1 0.2 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 0.3 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.1 1.6 GO:0005513 detection of calcium ion(GO:0005513)
0.1 2.7 GO:0021542 dentate gyrus development(GO:0021542)
0.1 3.8 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 1.0 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.1 0.3 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 3.8 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.1 2.1 GO:0021772 olfactory bulb development(GO:0021772)
0.1 0.7 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.1 8.0 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 3.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.9 GO:0034770 histone H4-K20 methylation(GO:0034770)
0.1 0.3 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.1 1.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 3.2 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.1 1.6 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 0.7 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.4 GO:1901660 calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
0.1 0.5 GO:0035624 receptor transactivation(GO:0035624)
0.1 0.4 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 2.2 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.1 0.3 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.1 0.1 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 1.0 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 0.6 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.1 0.6 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.1 0.9 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.9 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.4 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.4 GO:0070459 prolactin secretion(GO:0070459)
0.1 2.8 GO:1903078 positive regulation of protein localization to plasma membrane(GO:1903078)
0.1 0.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 1.6 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.3 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 1.5 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 0.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.5 GO:1902947 regulation of tau-protein kinase activity(GO:1902947)
0.1 0.6 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.1 0.6 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 1.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 0.4 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 1.6 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.1 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.5 GO:0016584 nucleosome positioning(GO:0016584)
0.1 2.2 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.1 4.1 GO:0021762 substantia nigra development(GO:0021762)
0.1 0.4 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.9 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 0.6 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.5 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 0.8 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 2.0 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 0.9 GO:0045116 protein neddylation(GO:0045116)
0.1 0.5 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.1 5.3 GO:0055072 iron ion homeostasis(GO:0055072)
0.1 0.9 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.1 1.8 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 0.4 GO:0097490 sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.1 1.3 GO:0009299 mRNA transcription(GO:0009299)
0.0 1.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.7 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.3 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.6 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.3 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 1.6 GO:0060612 adipose tissue development(GO:0060612)
0.0 2.1 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 1.2 GO:0097503 sialylation(GO:0097503)
0.0 2.5 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.0 GO:2001038 regulation of cellular response to drug(GO:2001038)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.9 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 2.5 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 6.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.8 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.4 GO:0015791 polyol transport(GO:0015791)
0.0 0.4 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 1.3 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.8 GO:0044070 regulation of anion transport(GO:0044070)
0.0 0.3 GO:0099624 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914) atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.0 0.3 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 1.2 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.3 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.4 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.6 GO:0001764 neuron migration(GO:0001764)
0.0 2.9 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.3 GO:0051963 regulation of synapse assembly(GO:0051963) positive regulation of synapse assembly(GO:0051965)
0.0 0.2 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 1.8 GO:0006284 base-excision repair(GO:0006284)
0.0 0.6 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 1.9 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.1 GO:1900122 B-1 B cell differentiation(GO:0001923) positive regulation of receptor binding(GO:1900122)
0.0 0.3 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.5 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.4 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 1.5 GO:0051058 negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 4.5 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.7 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 1.8 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.3 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.0 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0 2.9 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.3 GO:0001935 endothelial cell proliferation(GO:0001935)
0.0 0.3 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.7 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.3 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.7 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.9 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.1 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.0 0.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.8 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 3.0 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.7 GO:0001706 endoderm formation(GO:0001706)
0.0 4.3 GO:0090305 nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.0 3.7 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.2 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 1.4 GO:0045666 positive regulation of neuron differentiation(GO:0045666)
0.0 0.3 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.7 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.1 GO:0071799 adenosine metabolic process(GO:0046085) response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.2 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.2 GO:0050673 epithelial cell proliferation(GO:0050673)
0.0 0.2 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.3 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.2 GO:0061025 membrane fusion(GO:0061025)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0060674 placenta blood vessel development(GO:0060674)
0.0 0.5 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 11.0 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
1.2 6.1 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
1.0 4.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
1.0 5.0 GO:0045298 tubulin complex(GO:0045298)
0.7 2.1 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.7 5.4 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.7 7.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.7 3.3 GO:0070847 core mediator complex(GO:0070847)
0.6 4.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.6 1.8 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.6 2.3 GO:0016939 kinesin II complex(GO:0016939)
0.6 1.7 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.5 1.4 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.4 4.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.4 1.6 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.4 1.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 5.8 GO:0043194 axon initial segment(GO:0043194)
0.3 0.3 GO:0044305 calyx of Held(GO:0044305)
0.3 2.6 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.3 1.3 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.3 2.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.3 1.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.3 3.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 2.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 0.9 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 1.2 GO:0005899 insulin receptor complex(GO:0005899)
0.2 2.7 GO:0016342 catenin complex(GO:0016342)
0.2 0.7 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.2 1.7 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 0.6 GO:0005879 axonemal microtubule(GO:0005879)
0.2 2.9 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.2 0.8 GO:0070876 SOSS complex(GO:0070876)
0.2 0.6 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.2 0.9 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.2 0.5 GO:0031213 RSF complex(GO:0031213)
0.2 0.9 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.2 8.2 GO:0048786 presynaptic active zone(GO:0048786)
0.2 0.7 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.2 1.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 0.8 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 2.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 2.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 1.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.4 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 2.7 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 0.7 GO:0061689 tricellular tight junction(GO:0061689)
0.1 1.1 GO:0071953 elastic fiber(GO:0071953)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 6.9 GO:0030315 T-tubule(GO:0030315)
0.1 0.6 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.6 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 3.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.6 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.3 GO:0043293 apoptosome(GO:0043293)
0.1 9.1 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 3.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 2.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.7 GO:0033391 chromatoid body(GO:0033391)
0.1 3.5 GO:0042734 presynaptic membrane(GO:0042734)
0.1 2.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 11.7 GO:0030426 growth cone(GO:0030426)
0.1 1.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.1 3.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 6.0 GO:0005814 centriole(GO:0005814)
0.1 3.5 GO:0043195 terminal bouton(GO:0043195)
0.1 1.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 2.4 GO:0005771 multivesicular body(GO:0005771)
0.0 2.6 GO:0030120 vesicle coat(GO:0030120)
0.0 4.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 6.6 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.7 GO:0031045 dense core granule(GO:0031045)
0.0 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 2.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.0 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 4.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.4 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 4.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.8 GO:0043209 myelin sheath(GO:0043209)
0.0 0.6 GO:0042627 chylomicron(GO:0042627)
0.0 7.5 GO:0030424 axon(GO:0030424)
0.0 3.8 GO:0070160 occluding junction(GO:0070160)
0.0 0.4 GO:0031985 Golgi cisterna(GO:0031985) Golgi cisterna membrane(GO:0032580)
0.0 0.4 GO:0042588 zymogen granule(GO:0042588)
0.0 0.3 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 2.9 GO:0043204 perikaryon(GO:0043204)
0.0 2.4 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 1.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 2.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.7 GO:0005902 microvillus(GO:0005902)
0.0 2.7 GO:0005903 brush border(GO:0005903)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.9 GO:0016235 aggresome(GO:0016235)
0.0 7.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.2 GO:0034702 ion channel complex(GO:0034702)
0.0 2.0 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.6 GO:0005844 polysome(GO:0005844)
0.0 2.0 GO:0005783 endoplasmic reticulum(GO:0005783)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.6 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
1.4 4.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
1.4 4.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
1.3 5.0 GO:0099609 microtubule lateral binding(GO:0099609)
1.2 6.1 GO:0030348 syntaxin-3 binding(GO:0030348)
1.2 3.5 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
1.0 2.9 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.9 4.7 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.8 5.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.8 2.4 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.8 3.8 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.7 4.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.7 2.0 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.6 1.7 GO:0070699 type II activin receptor binding(GO:0070699)
0.5 2.7 GO:0070097 delta-catenin binding(GO:0070097)
0.5 5.0 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.4 5.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.4 11.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.4 1.3 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.4 1.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.4 1.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.4 2.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.4 1.1 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.4 1.5 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.4 3.0 GO:0050816 phosphothreonine binding(GO:0050816)
0.4 1.1 GO:0015616 DNA translocase activity(GO:0015616)
0.3 2.7 GO:0045295 gamma-catenin binding(GO:0045295)
0.3 2.6 GO:0097322 7SK snRNA binding(GO:0097322)
0.3 3.5 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.3 1.9 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.3 1.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.3 0.9 GO:0032184 SUMO polymer binding(GO:0032184)
0.3 0.9 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.3 5.7 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.3 2.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.3 0.9 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.3 1.0 GO:0017089 glycolipid transporter activity(GO:0017089)
0.3 1.8 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.3 2.0 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 1.4 GO:0038064 collagen receptor activity(GO:0038064)
0.2 2.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 4.6 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.2 2.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 1.5 GO:0017002 activin-activated receptor activity(GO:0017002)
0.2 0.6 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.2 0.8 GO:1904929 coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.2 3.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 2.0 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 0.6 GO:0050405 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.2 2.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.2 0.6 GO:0017129 triglyceride binding(GO:0017129)
0.2 3.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 4.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.2 1.6 GO:0048495 Roundabout binding(GO:0048495)
0.2 0.7 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.2 8.1 GO:0003785 actin monomer binding(GO:0003785)
0.2 2.2 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.2 1.0 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.2 8.5 GO:0030507 spectrin binding(GO:0030507)
0.2 2.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2 0.9 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.6 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 3.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.4 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 3.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 1.1 GO:0043559 insulin binding(GO:0043559)
0.1 4.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 2.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 3.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 2.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.4 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 1.3 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 1.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.9 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 7.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.8 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 2.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 2.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 7.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.6 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 2.0 GO:0016646 aldehyde dehydrogenase (NAD) activity(GO:0004029) oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 0.3 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 1.7 GO:0070330 aromatase activity(GO:0070330)
0.1 1.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 1.4 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.1 1.6 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.1 0.4 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 2.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.6 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 10.1 GO:0004519 endonuclease activity(GO:0004519)
0.1 2.0 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.3 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1 1.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 4.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.5 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 5.2 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.6 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 1.0 GO:0016004 phospholipase activator activity(GO:0016004)
0.1 2.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.2 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 1.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.7 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.2 GO:0046934 phosphatidylinositol 3-kinase activity(GO:0035004) phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.1 0.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 1.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 2.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.7 GO:0070700 BMP receptor binding(GO:0070700)
0.1 1.1 GO:0005112 Notch binding(GO:0005112)
0.1 1.0 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.1 0.8 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 3.5 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.0 2.4 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.3 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.3 GO:0031705 bombesin receptor binding(GO:0031705)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 1.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 5.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.8 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.4 GO:0043236 laminin binding(GO:0043236)
0.0 3.3 GO:0002039 p53 binding(GO:0002039)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.3 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.6 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.8 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.4 GO:0048185 activin binding(GO:0048185)
0.0 1.0 GO:0030332 cyclin binding(GO:0030332)
0.0 2.2 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.6 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 2.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 4.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.9 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.7 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.5 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.0 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 4.5 GO:0008017 microtubule binding(GO:0008017)
0.0 1.6 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 3.6 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.6 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 1.5 GO:0043130 ubiquitin binding(GO:0043130)
0.0 1.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.8 GO:0008374 O-acyltransferase activity(GO:0008374)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 0.8 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.3 GO:0019894 kinesin binding(GO:0019894)
0.0 0.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.9 GO:0051117 ATPase binding(GO:0051117)
0.0 0.3 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.3 GO:0042056 chemoattractant activity(GO:0042056)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.4 21.8 PID REELIN PATHWAY Reelin signaling pathway
0.4 1.7 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.3 2.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3 0.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.2 7.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 3.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 1.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 2.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 4.3 PID MYC PATHWAY C-MYC pathway
0.1 2.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 1.3 PID ALK2 PATHWAY ALK2 signaling events
0.1 4.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 3.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 3.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 0.9 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 2.1 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 4.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 0.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 1.2 PID RAS PATHWAY Regulation of Ras family activation
0.1 1.3 PID SHP2 PATHWAY SHP2 signaling
0.1 1.9 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 1.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.7 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.3 ST GAQ PATHWAY G alpha q Pathway
0.0 1.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 4.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 3.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 2.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 2.4 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.7 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 5.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.3 ST ADRENERGIC Adrenergic Pathway
0.0 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.3 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.1 PID GLYPICAN 1PATHWAY Glypican 1 network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 17.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.4 0.9 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.3 8.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 5.2 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.2 4.1 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 3.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 2.0 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.2 3.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 4.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 2.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 5.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 1.2 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 2.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 5.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 6.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 4.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 3.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.7 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 1.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 2.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 1.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 2.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 2.1 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 8.0 REACTOME RNA POL II PRE TRANSCRIPTION EVENTS Genes involved in RNA Polymerase II Pre-transcription Events
0.1 0.5 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 1.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 4.3 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 1.7 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 2.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 2.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.9 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 1.6 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 0.9 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 2.5 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 1.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.4 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.1 2.0 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 1.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 2.0 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.5 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 2.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.7 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.6 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.4 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.8 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.2 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 1.0 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.9 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.3 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.8 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 0.8 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.0 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 1.0 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes