Project

GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

Navigation
Downloads

Results for UGUGCUU

Z-value: 1.48

Motif logo

logo of

miRNA associated with seed UGUGCUU

NamemiRBASE accession
hsa-miR-218-5p
MIMAT0000275

Activity profile of UGUGCUU motif

Sorted Z-values of UGUGCUU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_93405352 33.52 ENST00000375765.3
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr4_+_158141843 31.16 ENST00000509417.1
ENST00000296526.7
GRIA2
glutamate receptor, ionotropic, AMPA 2
chr16_+_58497567 30.19 ENST00000258187.5
NDRG4
NDRG family member 4
chr12_-_16761007 30.08 ENST00000354662.1
ENST00000441439.2
LMO3
LIM domain only 3 (rhombotin-like 2)
chr5_-_176057365 30.03 ENST00000310112.3
SNCB
synuclein, beta
chr12_+_79258547 29.89 ENST00000457153.2
SYT1
synaptotagmin I
chr11_-_134281812 29.36 ENST00000392580.1
ENST00000312527.4
B3GAT1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr11_+_62475130 28.24 ENST00000294117.5
GNG3
guanine nucleotide binding protein (G protein), gamma 3
chr3_+_11034403 27.43 ENST00000287766.4
ENST00000425938.1
SLC6A1
solute carrier family 6 (neurotransmitter transporter), member 1
chr16_-_19896220 27.10 ENST00000562469.1
ENST00000300571.2
GPRC5B
G protein-coupled receptor, family C, group 5, member B
chr19_+_19322758 26.79 ENST00000252575.6
NCAN
neurocan
chr15_+_91643442 26.76 ENST00000394232.1
SV2B
synaptic vesicle glycoprotein 2B
chr13_+_27131887 26.11 ENST00000335327.5
WASF3
WAS protein family, member 3
chr2_+_231729615 24.78 ENST00000326427.6
ENST00000335005.6
ENST00000326407.6
ITM2C
integral membrane protein 2C
chr9_+_130374537 24.40 ENST00000373302.3
ENST00000373299.1
STXBP1
syntaxin binding protein 1
chr1_-_41131326 23.92 ENST00000372684.3
RIMS3
regulating synaptic membrane exocytosis 3
chr5_-_11904152 23.15 ENST00000304623.8
ENST00000458100.2
CTNND2
catenin (cadherin-associated protein), delta 2
chrX_+_110339439 22.32 ENST00000372010.1
ENST00000519681.1
ENST00000372007.5
PAK3
p21 protein (Cdc42/Rac)-activated kinase 3
chr3_+_238273 21.51 ENST00000256509.2
CHL1
cell adhesion molecule L1-like
chr2_-_26205340 21.44 ENST00000264712.3
KIF3C
kinesin family member 3C
chr2_-_2334888 21.41 ENST00000428368.2
ENST00000399161.2
MYT1L
myelin transcription factor 1-like
chr20_+_34700333 21.20 ENST00000441639.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr3_+_49591881 20.46 ENST00000296452.4
BSN
bassoon presynaptic cytomatrix protein
chr9_-_91793675 20.43 ENST00000375835.4
ENST00000375830.1
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr22_-_39548627 20.43 ENST00000216133.5
CBX7
chromobox homolog 7
chr7_+_153584166 19.43 ENST00000404039.1
DPP6
dipeptidyl-peptidase 6
chr2_+_79740118 19.37 ENST00000496558.1
ENST00000451966.1
CTNNA2
catenin (cadherin-associated protein), alpha 2
chr1_-_21978312 18.32 ENST00000359708.4
ENST00000290101.4
RAP1GAP
RAP1 GTPase activating protein
chr16_+_56225248 17.74 ENST00000262493.6
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr1_-_149889382 16.29 ENST00000369145.1
ENST00000369146.3
SV2A
synaptic vesicle glycoprotein 2A
chr7_+_86273218 16.28 ENST00000361669.2
GRM3
glutamate receptor, metabotropic 3
chr8_-_18871159 15.35 ENST00000327040.8
ENST00000440756.2
PSD3
pleckstrin and Sec7 domain containing 3
chr16_+_22825475 15.26 ENST00000261374.3
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr11_-_12030629 14.97 ENST00000396505.2
DKK3
dickkopf WNT signaling pathway inhibitor 3
chr6_+_69345166 14.81 ENST00000370598.1
BAI3
brain-specific angiogenesis inhibitor 3
chr2_-_50574856 14.54 ENST00000342183.5
NRXN1
neurexin 1
chr3_-_56502375 14.40 ENST00000288221.6
ERC2
ELKS/RAB6-interacting/CAST family member 2
chr6_+_121756809 14.35 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr14_+_90863327 14.31 ENST00000356978.4
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chrX_+_153665248 13.50 ENST00000447750.2
GDI1
GDP dissociation inhibitor 1
chr20_-_4804244 13.31 ENST00000379400.3
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr7_+_97361218 13.25 ENST00000319273.5
TAC1
tachykinin, precursor 1
chr15_+_75287861 13.18 ENST00000425597.3
ENST00000562327.1
ENST00000568018.1
ENST00000562212.1
ENST00000567920.1
ENST00000566872.1
ENST00000361900.6
ENST00000545456.1
SCAMP5
secretory carrier membrane protein 5
chr16_+_1756162 13.03 ENST00000250894.4
ENST00000356010.5
MAPK8IP3
mitogen-activated protein kinase 8 interacting protein 3
chr3_-_66551351 12.79 ENST00000273261.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr5_+_76506706 12.43 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
PDE8B
phosphodiesterase 8B
chr3_+_33318914 12.05 ENST00000484457.1
ENST00000538892.1
ENST00000538181.1
ENST00000446237.3
ENST00000507198.1
FBXL2
F-box and leucine-rich repeat protein 2
chr1_-_57045228 12.01 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr1_-_109584608 11.92 ENST00000400794.3
ENST00000528747.1
ENST00000369962.3
ENST00000361054.3
WDR47
WD repeat domain 47
chr7_-_79082867 11.89 ENST00000419488.1
ENST00000354212.4
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_+_173600671 11.72 ENST00000409036.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr2_+_159313452 11.51 ENST00000389757.3
ENST00000389759.3
PKP4
plakophilin 4
chr19_-_17799008 11.25 ENST00000519716.2
UNC13A
unc-13 homolog A (C. elegans)
chr10_-_97321112 11.22 ENST00000607232.1
ENST00000371227.4
ENST00000371249.2
ENST00000371247.2
ENST00000371246.2
ENST00000393949.1
ENST00000353505.5
ENST00000347291.4
SORBS1
sorbin and SH3 domain containing 1
chr4_-_99579733 11.21 ENST00000305798.3
TSPAN5
tetraspanin 5
chr20_+_2854066 11.15 ENST00000455631.1
ENST00000216877.6
ENST00000399903.2
ENST00000358719.4
ENST00000431048.1
ENST00000425918.2
ENST00000430705.1
ENST00000318266.5
PTPRA
protein tyrosine phosphatase, receptor type, A
chr7_-_103629963 10.80 ENST00000428762.1
ENST00000343529.5
ENST00000424685.2
RELN
reelin
chr17_-_40021656 10.70 ENST00000319121.3
KLHL11
kelch-like family member 11
chr20_-_48099182 10.42 ENST00000371741.4
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr15_-_52861394 10.38 ENST00000563277.1
ENST00000566423.1
ARPP19
cAMP-regulated phosphoprotein, 19kDa
chr14_+_85996471 10.33 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr6_+_148663729 10.25 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1
chr18_-_53255766 10.15 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr18_+_21693306 10.13 ENST00000540918.2
TTC39C
tetratricopeptide repeat domain 39C
chr16_-_68482440 9.75 ENST00000219334.5
SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr17_+_53342311 9.53 ENST00000226067.5
HLF
hepatic leukemia factor
chr7_-_44924939 9.52 ENST00000395699.2
PURB
purine-rich element binding protein B
chr14_-_77843390 9.46 ENST00000216468.7
TMED8
transmembrane emp24 protein transport domain containing 8
chr4_+_62066941 9.45 ENST00000512091.2
LPHN3
latrophilin 3
chr12_+_41086297 9.44 ENST00000551295.2
CNTN1
contactin 1
chr11_+_113930291 9.38 ENST00000335953.4
ZBTB16
zinc finger and BTB domain containing 16
chr7_+_106685079 9.18 ENST00000265717.4
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr13_-_53422640 9.16 ENST00000338862.4
ENST00000377942.3
PCDH8
protocadherin 8
chr2_-_86850949 9.10 ENST00000237455.4
RNF103
ring finger protein 103
chr1_-_6321035 8.77 ENST00000377893.2
GPR153
G protein-coupled receptor 153
chr9_+_34958254 8.75 ENST00000242315.3
KIAA1045
KIAA1045
chr5_-_115910630 8.71 ENST00000343348.6
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr14_+_69658194 8.57 ENST00000409018.3
ENST00000409014.1
ENST00000409675.1
EXD2
exonuclease 3'-5' domain containing 2
chr14_+_79745746 8.57 ENST00000281127.7
NRXN3
neurexin 3
chr2_-_47798044 8.56 ENST00000327876.4
KCNK12
potassium channel, subfamily K, member 12
chr8_-_53322303 8.48 ENST00000276480.7
ST18
suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)
chr20_-_41818373 8.28 ENST00000373187.1
ENST00000356100.2
ENST00000373184.1
ENST00000373190.1
PTPRT
protein tyrosine phosphatase, receptor type, T
chr11_-_118047376 8.23 ENST00000278947.5
SCN2B
sodium channel, voltage-gated, type II, beta subunit
chr10_+_96162242 8.19 ENST00000225235.4
TBC1D12
TBC1 domain family, member 12
chr6_+_96463840 8.04 ENST00000302103.5
FUT9
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr14_-_51562745 7.98 ENST00000298355.3
TRIM9
tripartite motif containing 9
chr4_+_85504075 7.94 ENST00000295887.5
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr18_-_11148587 7.91 ENST00000302079.6
ENST00000580640.1
ENST00000503781.3
PIEZO2
piezo-type mechanosensitive ion channel component 2
chr15_+_59063478 7.74 ENST00000559228.1
ENST00000450403.2
FAM63B
family with sequence similarity 63, member B
chr5_+_67511524 7.71 ENST00000521381.1
ENST00000521657.1
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr11_-_45307817 7.67 ENST00000020926.3
SYT13
synaptotagmin XIII
chr1_-_200992827 7.66 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr11_+_111473108 7.64 ENST00000304987.3
SIK2
salt-inducible kinase 2
chrX_-_153237258 7.60 ENST00000310441.7
HCFC1
host cell factor C1 (VP16-accessory protein)
chr19_-_14316980 7.59 ENST00000361434.3
ENST00000340736.6
LPHN1
latrophilin 1
chr20_-_47894569 7.54 ENST00000371744.1
ENST00000371752.1
ENST00000396105.1
ZNFX1
zinc finger, NFX1-type containing 1
chr11_+_118401706 7.42 ENST00000411589.2
ENST00000442938.2
ENST00000359862.4
TMEM25
transmembrane protein 25
chr3_-_192445289 7.40 ENST00000430714.1
ENST00000418610.1
ENST00000448795.1
ENST00000445105.2
FGF12
fibroblast growth factor 12
chr7_-_121036337 7.36 ENST00000426156.1
ENST00000359943.3
ENST00000412653.1
FAM3C
family with sequence similarity 3, member C
chr2_-_166930131 7.33 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr11_-_118661828 7.13 ENST00000264018.4
DDX6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr14_+_74111578 7.05 ENST00000554113.1
ENST00000555631.2
ENST00000553645.2
ENST00000311089.3
ENST00000555919.3
ENST00000554339.1
ENST00000554871.1
DNAL1
dynein, axonemal, light chain 1
chr5_+_140306478 7.02 ENST00000253807.2
PCDHAC1
protocadherin alpha subfamily C, 1
chr13_-_67804445 6.92 ENST00000456367.1
ENST00000377861.3
ENST00000544246.1
PCDH9
protocadherin 9
chrX_+_56259316 6.90 ENST00000468660.1
KLF8
Kruppel-like factor 8
chr5_+_140220769 6.76 ENST00000531613.1
ENST00000378123.3
PCDHA8
protocadherin alpha 8
chr22_+_25202232 6.73 ENST00000400358.4
ENST00000400359.4
SGSM1
small G protein signaling modulator 1
chr12_-_54673871 6.69 ENST00000209875.4
CBX5
chromobox homolog 5
chr17_-_33416231 6.47 ENST00000584655.1
ENST00000447669.2
ENST00000315249.7
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr10_+_99344104 6.46 ENST00000555577.1
ENST00000370649.3
PI4K2A
PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
Phosphatidylinositol 4-kinase type 2-alpha; Uncharacterized protein
chr10_-_104474128 6.45 ENST00000260746.5
ARL3
ADP-ribosylation factor-like 3
chr18_+_42260861 6.40 ENST00000282030.5
SETBP1
SET binding protein 1
chr14_+_32546485 6.37 ENST00000345122.3
ENST00000432921.1
ENST00000433497.1
ARHGAP5
Rho GTPase activating protein 5
chr5_+_140254884 6.28 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr10_+_76871454 6.25 ENST00000372687.4
SAMD8
sterile alpha motif domain containing 8
chr10_+_104678032 6.24 ENST00000369878.4
ENST00000369875.3
CNNM2
cyclin M2
chr2_-_152955537 6.21 ENST00000201943.5
ENST00000539935.1
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr20_+_58508817 6.20 ENST00000358293.3
FAM217B
family with sequence similarity 217, member B
chr19_+_1752372 6.15 ENST00000382349.4
ONECUT3
one cut homeobox 3
chr5_+_140227048 6.15 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr5_+_140213815 6.13 ENST00000525929.1
ENST00000378125.3
PCDHA7
protocadherin alpha 7
chr1_-_118472216 6.12 ENST00000369443.5
GDAP2
ganglioside induced differentiation associated protein 2
chr11_-_70507901 6.08 ENST00000449833.2
ENST00000357171.3
ENST00000449116.2
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr5_+_140248518 6.04 ENST00000398640.2
PCDHA11
protocadherin alpha 11
chr17_+_14204389 5.99 ENST00000360954.2
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr15_-_77363513 5.95 ENST00000267970.4
TSPAN3
tetraspanin 3
chr6_+_43543942 5.91 ENST00000372226.1
ENST00000443535.1
POLH
polymerase (DNA directed), eta
chr8_+_86376081 5.85 ENST00000285379.5
CA2
carbonic anhydrase II
chr4_-_10686475 5.66 ENST00000226951.6
CLNK
cytokine-dependent hematopoietic cell linker
chr3_+_32147997 5.62 ENST00000282541.5
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr18_+_13218769 5.58 ENST00000399848.3
ENST00000361205.4
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr5_+_139493665 5.56 ENST00000331327.3
PURA
purine-rich element binding protein A
chr12_+_72666407 5.51 ENST00000261180.4
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr3_+_57541975 5.48 ENST00000487257.1
ENST00000311180.8
PDE12
phosphodiesterase 12
chr1_+_220701456 5.44 ENST00000366918.4
ENST00000402574.1
MARK1
MAP/microtubule affinity-regulating kinase 1
chr5_+_140345820 5.44 ENST00000289269.5
PCDHAC2
protocadherin alpha subfamily C, 2
chr9_-_123476719 5.35 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr12_-_89918522 5.33 ENST00000529983.2
GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr2_+_172544182 5.32 ENST00000409197.1
ENST00000456808.1
ENST00000409317.1
ENST00000409773.1
ENST00000411953.1
ENST00000409453.1
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr17_+_5031687 5.32 ENST00000250066.6
ENST00000304328.5
USP6
ubiquitin specific peptidase 6 (Tre-2 oncogene)
chr9_+_131843377 5.29 ENST00000372546.4
ENST00000406974.3
ENST00000540102.1
DOLPP1
dolichyldiphosphatase 1
chr13_+_97874574 5.25 ENST00000343600.4
ENST00000345429.6
ENST00000376673.3
MBNL2
muscleblind-like splicing regulator 2
chr1_+_184356188 5.25 ENST00000235307.6
C1orf21
chromosome 1 open reading frame 21
chr12_+_31812602 5.16 ENST00000538463.1
ENST00000357721.3
ENST00000539633.1
METTL20
methyltransferase like 20
chr1_-_208417620 5.16 ENST00000367033.3
PLXNA2
plexin A2
chr4_+_115519577 5.15 ENST00000310836.6
UGT8
UDP glycosyltransferase 8
chr11_-_78052923 5.12 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr6_-_128841503 5.10 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
PTPRK
protein tyrosine phosphatase, receptor type, K
chr2_-_213403565 5.08 ENST00000342788.4
ENST00000436443.1
ERBB4
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
chr17_+_48638371 5.02 ENST00000360761.4
ENST00000352832.5
ENST00000354983.4
CACNA1G
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr11_-_73472096 5.02 ENST00000541588.1
ENST00000336083.3
ENST00000540771.1
ENST00000310653.6
RAB6A
RAB6A, member RAS oncogene family
chr15_+_78441663 4.89 ENST00000299518.2
ENST00000558554.1
ENST00000557826.1
ENST00000561279.1
ENST00000559186.1
ENST00000560770.1
ENST00000559881.1
ENST00000559205.1
ENST00000441490.2
IDH3A
isocitrate dehydrogenase 3 (NAD+) alpha
chr11_+_73882144 4.87 ENST00000328257.8
PPME1
protein phosphatase methylesterase 1
chrX_+_133507327 4.83 ENST00000332070.3
ENST00000394292.1
ENST00000370799.1
ENST00000416404.2
PHF6
PHD finger protein 6
chr19_-_38714847 4.76 ENST00000420980.2
ENST00000355526.4
DPF1
D4, zinc and double PHD fingers family 1
chr12_+_120875910 4.70 ENST00000551806.1
AL021546.6
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial
chr13_+_58206655 4.65 ENST00000377918.3
PCDH17
protocadherin 17
chr4_+_55524085 4.40 ENST00000412167.2
ENST00000288135.5
KIT
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr8_-_93115445 4.39 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_-_99224915 4.38 ENST00000328709.3
ENST00000409997.1
COA5
cytochrome c oxidase assembly factor 5
chr2_+_5832799 4.34 ENST00000322002.3
SOX11
SRY (sex determining region Y)-box 11
chr9_-_73029540 4.31 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr8_-_82024290 4.25 ENST00000220597.4
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr4_+_99182593 4.25 ENST00000508213.1
ENST00000408927.3
ENST00000514122.1
ENST00000453712.2
ENST00000511212.1
ENST00000408900.3
ENST00000339360.5
RAP1GDS1
RAP1, GTP-GDP dissociation stimulator 1
chr10_+_126490354 4.23 ENST00000298492.5
FAM175B
family with sequence similarity 175, member B
chr17_-_62207485 4.20 ENST00000433197.3
ERN1
endoplasmic reticulum to nucleus signaling 1
chr9_+_129089088 4.17 ENST00000361171.3
ENST00000545391.1
MVB12B
multivesicular body subunit 12B
chr1_-_52831796 4.13 ENST00000284376.3
ENST00000438831.1
ENST00000371586.2
CC2D1B
coiled-coil and C2 domain containing 1B
chr15_-_86338134 4.08 ENST00000337975.5
KLHL25
kelch-like family member 25
chr5_-_132299313 4.07 ENST00000265343.5
AFF4
AF4/FMR2 family, member 4
chr20_+_3451650 4.06 ENST00000262919.5
ATRN
attractin
chrX_+_24167746 4.03 ENST00000428571.1
ENST00000539115.1
ZFX
zinc finger protein, X-linked
chr7_+_99613195 4.02 ENST00000324306.6
ZKSCAN1
zinc finger with KRAB and SCAN domains 1
chr16_+_19535133 4.01 ENST00000396212.2
ENST00000381396.5
CCP110
centriolar coiled coil protein 110kDa
chr1_+_41249539 3.99 ENST00000347132.5
ENST00000509682.2
KCNQ4
potassium voltage-gated channel, KQT-like subfamily, member 4
chr12_+_5019061 3.92 ENST00000382545.3
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr8_+_12803176 3.91 ENST00000524591.2
KIAA1456
KIAA1456
chr9_+_112403088 3.91 ENST00000448454.2
PALM2
paralemmin 2
chr17_+_46125707 3.89 ENST00000584137.1
ENST00000362042.3
ENST00000585291.1
ENST00000357480.5
NFE2L1
nuclear factor, erythroid 2-like 1
chr12_-_89919965 3.88 ENST00000548729.1
POC1B-GALNT4
POC1B-GALNT4 readthrough
chr9_-_3525968 3.85 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
RFX3
regulatory factor X, 3 (influences HLA class II expression)
chr5_-_9546180 3.78 ENST00000382496.5
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr1_+_174769006 3.73 ENST00000489615.1
RABGAP1L
RAB GTPase activating protein 1-like
chr15_-_25684110 3.69 ENST00000232165.3
UBE3A
ubiquitin protein ligase E3A
chr9_+_131873591 3.66 ENST00000393370.2
ENST00000337738.1
ENST00000348141.5
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr5_-_112630598 3.66 ENST00000302475.4
MCC
mutated in colorectal cancers
chr5_+_140165876 3.65 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
PCDHA1
protocadherin alpha 1
chr7_+_49813255 3.64 ENST00000340652.4
VWC2
von Willebrand factor C domain containing 2
chr19_+_34112850 3.64 ENST00000591231.1
ENST00000434302.1
ENST00000438847.3
CHST8
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
chr12_-_100536608 3.51 ENST00000356828.3
ENST00000279907.7
UHRF1BP1L
UHRF1 binding protein 1-like
chr12_-_71148413 3.49 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr7_+_138916231 3.45 ENST00000473989.3
ENST00000288561.8
UBN2
ubinuclein 2
chr11_+_119076745 3.45 ENST00000264033.4
CBL
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr12_+_120884222 3.37 ENST00000551765.1
ENST00000229384.5
GATC
glutamyl-tRNA(Gln) amidotransferase, subunit C
chrX_-_153363188 3.33 ENST00000303391.6
MECP2
methyl CpG binding protein 2 (Rett syndrome)
chr18_-_44336998 3.31 ENST00000315087.7
ST8SIA5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr18_+_33877654 3.29 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
FHOD3
formin homology 2 domain containing 3
chr7_-_71801980 3.27 ENST00000329008.5
CALN1
calneuron 1
chr3_+_39093481 3.24 ENST00000302313.5
ENST00000544962.1
ENST00000396258.3
ENST00000418020.1
WDR48
WD repeat domain 48
chr13_-_40177261 3.24 ENST00000379589.3
LHFP
lipoma HMGIC fusion partner

Network of associatons between targets according to the STRING database.

First level regulatory network of UGUGCUU

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
10.0 29.9 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
8.9 35.6 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
6.9 27.4 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
6.1 18.3 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
5.9 11.9 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
5.0 30.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
4.4 13.2 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
4.3 12.8 GO:0032474 otolith morphogenesis(GO:0032474)
3.7 15.0 GO:1990262 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
3.6 14.4 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
3.3 16.3 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
3.1 3.1 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
3.1 24.8 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
2.9 8.7 GO:0002276 basophil activation involved in immune response(GO:0002276)
2.8 5.6 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
2.7 10.8 GO:0097114 NMDA glutamate receptor clustering(GO:0097114) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
2.6 10.4 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
2.6 10.3 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
2.6 10.3 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
2.4 7.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
2.3 4.6 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
2.3 30.2 GO:2001135 regulation of endocytic recycling(GO:2001135)
1.9 5.8 GO:0042938 dipeptide transport(GO:0042938)
1.9 7.6 GO:0019046 release from viral latency(GO:0019046)
1.9 13.3 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
1.9 3.8 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
1.9 9.4 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) positive regulation of NK T cell differentiation(GO:0051138) germline stem cell asymmetric division(GO:0098728)
1.8 9.2 GO:0097338 response to clozapine(GO:0097338)
1.8 14.5 GO:0097106 postsynaptic density organization(GO:0097106) postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116) neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
1.7 22.3 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
1.7 5.1 GO:2000366 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
1.7 13.5 GO:0032482 Rab protein signal transduction(GO:0032482)
1.6 6.5 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
1.6 27.1 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
1.5 4.4 GO:0048170 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) erythropoietin-mediated signaling pathway(GO:0038162) positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
1.4 4.3 GO:0061386 closure of optic fissure(GO:0061386)
1.4 56.2 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
1.3 3.8 GO:0072560 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
1.2 2.4 GO:0010643 cell communication by chemical coupling(GO:0010643)
1.2 2.4 GO:0051462 cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462)
1.2 17.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
1.1 16.0 GO:1905038 regulation of sphingolipid biosynthetic process(GO:0090153) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
1.1 5.7 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
1.1 7.9 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
1.1 3.3 GO:1900114 positive regulation of histone H3-K9 trimethylation(GO:1900114)
1.1 13.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
1.0 4.0 GO:0032053 ciliary basal body organization(GO:0032053)
1.0 3.0 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
1.0 2.9 GO:1900158 negative regulation of osteoclast proliferation(GO:0090291) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.9 3.7 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.9 14.6 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.9 21.9 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.9 3.6 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.9 26.1 GO:0031643 positive regulation of myelination(GO:0031643)
0.9 11.3 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.9 8.6 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.8 5.9 GO:0071494 cellular response to UV-C(GO:0071494)
0.8 20.1 GO:0035640 exploration behavior(GO:0035640)
0.8 21.6 GO:0048665 neuron fate specification(GO:0048665)
0.8 9.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.8 15.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.8 5.3 GO:0006489 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.8 28.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.7 3.0 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.7 7.4 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.7 5.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.7 7.9 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.7 4.3 GO:0051414 response to cortisol(GO:0051414)
0.7 2.8 GO:0050915 sensory perception of sour taste(GO:0050915)
0.7 3.4 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.7 7.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.7 7.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.7 8.0 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.7 2.7 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.7 5.3 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.7 8.5 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.6 1.9 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.6 30.0 GO:0042417 dopamine metabolic process(GO:0042417)
0.6 1.9 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.6 6.8 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.6 1.9 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.6 10.4 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.6 2.4 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.6 27.1 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.6 7.0 GO:0036158 outer dynein arm assembly(GO:0036158)
0.6 27.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.6 27.9 GO:0042073 intraciliary transport(GO:0042073)
0.6 5.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.5 1.6 GO:0007497 posterior midgut development(GO:0007497)
0.5 3.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.5 6.2 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.5 2.6 GO:0071321 cellular response to cGMP(GO:0071321)
0.5 5.2 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.5 3.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.5 3.0 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.5 23.2 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.5 4.8 GO:0072520 seminiferous tubule development(GO:0072520)
0.5 75.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.5 5.6 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.5 20.4 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.4 11.2 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.4 3.9 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.4 13.0 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.4 2.8 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.4 2.7 GO:0007256 activation of JNKK activity(GO:0007256)
0.4 11.8 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.4 2.7 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
0.4 2.9 GO:0060017 parathyroid gland development(GO:0060017)
0.4 10.7 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.3 1.4 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.3 4.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.3 1.0 GO:0072276 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.3 4.2 GO:0014829 vascular smooth muscle contraction(GO:0014829)
0.3 2.6 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.3 1.0 GO:0021794 thalamus development(GO:0021794)
0.3 6.1 GO:0060292 long term synaptic depression(GO:0060292)
0.3 1.9 GO:0007296 vitellogenesis(GO:0007296)
0.3 22.4 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.3 6.0 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.3 4.2 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.3 9.4 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.3 2.1 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.3 8.9 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.3 7.1 GO:0000729 DNA double-strand break processing(GO:0000729)
0.3 3.6 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.3 1.5 GO:0035881 amacrine cell differentiation(GO:0035881)
0.2 2.0 GO:0002051 osteoblast fate commitment(GO:0002051)
0.2 0.7 GO:0060029 convergent extension involved in organogenesis(GO:0060029)
0.2 1.9 GO:0016926 protein desumoylation(GO:0016926)
0.2 3.0 GO:0045008 depyrimidination(GO:0045008)
0.2 0.9 GO:0006382 adenosine to inosine editing(GO:0006382) facial nerve development(GO:0021561) facial nerve morphogenesis(GO:0021610) motor behavior(GO:0061744)
0.2 2.6 GO:0045475 locomotor rhythm(GO:0045475)
0.2 16.5 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.2 1.3 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.2 6.2 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.2 1.9 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.2 3.1 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.2 15.3 GO:0006024 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.2 6.9 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.2 3.3 GO:0060384 innervation(GO:0060384)
0.2 13.5 GO:0007416 synapse assembly(GO:0007416)
0.2 1.0 GO:0035754 B cell chemotaxis(GO:0035754)
0.2 3.4 GO:0006450 regulation of translational fidelity(GO:0006450)
0.2 2.2 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.2 2.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 4.1 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.1 8.4 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.1 3.9 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 2.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 14.6 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.1 5.5 GO:0043171 peptide catabolic process(GO:0043171)
0.1 0.8 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 1.7 GO:2000505 regulation of energy homeostasis(GO:2000505)
0.1 1.9 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.6 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.6 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.1 0.7 GO:0021549 cerebellum development(GO:0021549)
0.1 0.3 GO:0060424 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.1 1.1 GO:0060081 membrane hyperpolarization(GO:0060081)
0.1 1.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.4 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 8.9 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 0.5 GO:1901538 DNA methylation involved in embryo development(GO:0043045) C-5 methylation of cytosine(GO:0090116) changes to DNA methylation involved in embryo development(GO:1901538)
0.1 1.1 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.6 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.7 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.1 2.7 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 2.1 GO:0010107 potassium ion import(GO:0010107)
0.1 14.0 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.1 6.3 GO:0030010 establishment of cell polarity(GO:0030010)
0.1 1.7 GO:0002076 osteoblast development(GO:0002076)
0.1 0.5 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.3 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.6 GO:0097503 sialylation(GO:0097503)
0.0 7.4 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 7.5 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.6 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 4.4 GO:0007286 spermatid development(GO:0007286)
0.0 1.2 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 1.9 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.4 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 1.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 3.0 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 1.3 GO:1901998 toxin transport(GO:1901998)
0.0 1.9 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.8 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 1.8 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 3.2 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 2.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 1.5 GO:0007004 telomere maintenance via telomerase(GO:0007004)
0.0 1.9 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 1.0 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.4 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.6 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.0 1.6 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.5 GO:0033344 cholesterol efflux(GO:0033344)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
6.2 31.2 GO:0098843 postsynaptic endocytic zone(GO:0098843)
6.0 29.9 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
4.1 20.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
3.1 9.4 GO:0044305 calyx of Held(GO:0044305)
2.2 11.2 GO:0005899 insulin receptor complex(GO:0005899)
2.2 8.7 GO:0035838 growing cell tip(GO:0035838)
1.9 7.7 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
1.8 75.9 GO:0048786 presynaptic active zone(GO:0048786)
1.5 11.9 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
1.4 9.7 GO:0000137 Golgi cis cisterna(GO:0000137)
1.0 4.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
1.0 7.1 GO:0001520 outer dense fiber(GO:0001520)
1.0 15.1 GO:0005662 DNA replication factor A complex(GO:0005662)
1.0 3.0 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.9 5.6 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.9 15.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.9 7.0 GO:0036157 outer dynein arm(GO:0036157)
0.8 5.0 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.8 11.3 GO:0035102 PRC1 complex(GO:0035102)
0.8 14.4 GO:0005922 connexon complex(GO:0005922)
0.7 2.9 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.6 44.6 GO:0042734 presynaptic membrane(GO:0042734)
0.6 6.1 GO:0005883 neurofilament(GO:0005883)
0.6 4.2 GO:0000813 ESCRT I complex(GO:0000813)
0.6 7.6 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.5 24.4 GO:0097542 ciliary tip(GO:0097542)
0.5 13.0 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.5 26.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.5 37.4 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.5 5.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.5 9.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.4 7.4 GO:0031089 platelet dense granule lumen(GO:0031089)
0.4 22.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.4 1.9 GO:0031905 early endosome lumen(GO:0031905)
0.4 11.5 GO:0051233 spindle midzone(GO:0051233)
0.4 6.7 GO:0010369 chromocenter(GO:0010369)
0.3 0.7 GO:0045298 tubulin complex(GO:0045298)
0.3 36.8 GO:0016234 inclusion body(GO:0016234)
0.3 2.4 GO:0044194 cytolytic granule(GO:0044194)
0.3 3.4 GO:0016600 flotillin complex(GO:0016600)
0.2 25.5 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.2 12.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 10.5 GO:0030496 midbody(GO:0030496)
0.2 6.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.2 66.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.2 27.7 GO:0005796 Golgi lumen(GO:0005796)
0.2 24.0 GO:0043204 perikaryon(GO:0043204)
0.2 4.8 GO:0071565 nBAF complex(GO:0071565)
0.2 2.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 6.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.2 3.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 4.4 GO:0042629 mast cell granule(GO:0042629)
0.1 5.3 GO:0005604 basement membrane(GO:0005604)
0.1 4.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.6 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 53.3 GO:0030424 axon(GO:0030424)
0.1 13.9 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 15.3 GO:0030027 lamellipodium(GO:0030027)
0.1 1.9 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 1.9 GO:0030478 actin cap(GO:0030478)
0.1 1.1 GO:0016013 syntrophin complex(GO:0016013)
0.1 33.3 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 5.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.6 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 2.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 3.1 GO:0031904 endosome lumen(GO:0031904)
0.1 2.3 GO:0001726 ruffle(GO:0001726)
0.1 5.1 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 11.5 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.4 GO:0070695 FHF complex(GO:0070695)
0.1 66.8 GO:0000139 Golgi membrane(GO:0000139)
0.1 9.0 GO:0000922 spindle pole(GO:0000922)
0.1 22.5 GO:0045177 apical part of cell(GO:0045177)
0.1 2.0 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 2.9 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 7.5 GO:0098793 presynapse(GO:0098793)
0.1 5.6 GO:0030426 growth cone(GO:0030426)
0.1 1.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 2.7 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.1 6.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 4.0 GO:0005814 centriole(GO:0005814)
0.1 3.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.5 GO:0001741 XY body(GO:0001741)
0.0 1.0 GO:0005902 microvillus(GO:0005902)
0.0 2.9 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)
0.0 55.3 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 2.1 GO:0016459 myosin complex(GO:0016459)
0.0 0.7 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 7.8 GO:0005874 microtubule(GO:0005874)
0.0 2.4 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 7.5 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 0.9 GO:0005770 late endosome(GO:0005770)
0.0 11.0 GO:0005615 extracellular space(GO:0005615)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.5 GO:0005776 autophagosome(GO:0005776)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
9.8 29.4 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
6.0 29.9 GO:0030348 syntaxin-3 binding(GO:0030348)
4.6 27.4 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
4.0 11.9 GO:0070699 type II activin receptor binding(GO:0070699)
3.6 10.8 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
3.5 21.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
3.3 16.3 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
2.6 7.9 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
2.6 31.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
2.4 14.4 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
2.3 23.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
2.2 8.7 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
2.2 6.5 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
2.1 30.0 GO:1903136 cuprous ion binding(GO:1903136)
2.1 6.2 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
1.9 5.6 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
1.8 9.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
1.7 8.3 GO:0070097 delta-catenin binding(GO:0070097)
1.6 8.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.6 17.7 GO:0051430 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
1.4 23.1 GO:0097109 neuroligin family protein binding(GO:0097109)
1.4 8.6 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
1.4 35.6 GO:0017075 syntaxin-1 binding(GO:0017075)
1.4 16.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
1.3 24.0 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
1.3 7.9 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
1.2 4.9 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
1.0 8.0 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
1.0 9.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.9 3.8 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.9 19.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.9 6.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.9 10.4 GO:0030552 cAMP binding(GO:0030552)
0.8 23.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.8 3.9 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.8 10.1 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.8 22.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.7 3.0 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.7 7.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.7 5.8 GO:0004064 arylesterase activity(GO:0004064)
0.7 18.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.7 8.0 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.6 16.7 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.6 12.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.6 3.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.6 15.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.6 2.9 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.6 2.9 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.6 9.1 GO:0045499 chemorepellent activity(GO:0045499)
0.6 9.0 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.6 2.8 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.6 9.5 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.6 13.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.5 5.3 GO:0016462 pyrophosphatase activity(GO:0016462)
0.5 3.1 GO:0043237 laminin-1 binding(GO:0043237)
0.5 1.5 GO:0015616 DNA translocase activity(GO:0015616)
0.5 1.9 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.5 2.4 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.5 9.2 GO:0008603 cAMP-dependent protein kinase inhibitor activity(GO:0004862) cAMP-dependent protein kinase regulator activity(GO:0008603)
0.4 6.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.4 4.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.4 26.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.4 26.5 GO:0003777 microtubule motor activity(GO:0003777)
0.3 12.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.3 15.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.3 1.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.3 7.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.3 6.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 3.3 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.3 5.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.3 13.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 5.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 3.4 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.2 4.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.2 3.0 GO:0015279 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2 40.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 5.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 0.9 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2 9.5 GO:0042169 SH2 domain binding(GO:0042169)
0.2 8.5 GO:0005158 insulin receptor binding(GO:0005158)
0.2 0.8 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.2 7.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.2 25.8 GO:0044325 ion channel binding(GO:0044325)
0.2 1.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 2.1 GO:0031386 protein tag(GO:0031386)
0.2 0.5 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.2 5.1 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.2 13.3 GO:0030295 protein kinase activator activity(GO:0030295)
0.2 7.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 2.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.6 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 12.3 GO:0002020 protease binding(GO:0002020)
0.1 1.0 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1 3.0 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 1.9 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.1 4.8 GO:0097110 scaffold protein binding(GO:0097110)
0.1 1.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 2.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 2.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 4.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 3.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.5 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 6.4 GO:0032947 protein complex scaffold(GO:0032947)
0.1 2.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.6 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1 2.2 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.9 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 5.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 6.7 GO:0002039 p53 binding(GO:0002039)
0.1 3.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 1.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 1.5 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.1 8.8 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 0.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 57.2 GO:0005509 calcium ion binding(GO:0005509)
0.1 24.6 GO:0005096 GTPase activator activity(GO:0005096)
0.1 3.6 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 5.2 GO:0008013 beta-catenin binding(GO:0008013)
0.1 0.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 1.9 GO:0030695 GTPase regulator activity(GO:0030695)
0.1 15.1 GO:0030246 carbohydrate binding(GO:0030246)
0.1 1.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.9 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.5 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 1.0 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.4 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 1.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 5.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.6 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 1.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 2.1 GO:0003774 motor activity(GO:0003774)
0.0 3.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 3.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.0 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 1.1 GO:0019787 ubiquitin-like protein transferase activity(GO:0019787)
0.0 5.6 GO:0005125 cytokine activity(GO:0005125)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 4.0 GO:0008017 microtubule binding(GO:0008017)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0039706 co-receptor binding(GO:0039706)
0.0 1.4 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.7 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.4 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 55.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.8 42.9 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.7 25.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.7 36.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.6 21.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.5 15.8 PID ERBB4 PATHWAY ErbB4 signaling events
0.4 17.7 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.3 3.8 PID S1P S1P4 PATHWAY S1P4 pathway
0.3 10.3 PID REELIN PATHWAY Reelin signaling pathway
0.2 9.2 PID TNF PATHWAY TNF receptor signaling pathway
0.2 4.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2 3.2 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.2 4.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.2 1.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 5.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 2.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 9.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 7.6 PID LKB1 PATHWAY LKB1 signaling events
0.1 4.2 PID SHP2 PATHWAY SHP2 signaling
0.1 2.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 3.5 PID INSULIN PATHWAY Insulin Pathway
0.1 6.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 2.5 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 13.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 3.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 6.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 1.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 23.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 1.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 2.0 PID FGF PATHWAY FGF signaling pathway
0.1 2.9 PID AURORA B PATHWAY Aurora B signaling
0.0 3.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.4 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 3.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 54.9 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
1.5 56.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
1.4 27.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
1.3 44.0 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
1.1 31.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
1.1 19.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
1.1 21.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.9 21.2 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.9 14.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.8 15.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.7 18.8 REACTOME KINESINS Genes involved in Kinesins
0.7 31.3 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.6 8.7 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.5 12.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.4 13.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.4 11.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.4 5.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.4 5.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.4 11.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.4 12.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.3 5.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.3 6.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.3 3.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.3 5.9 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.2 13.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 10.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.2 5.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 3.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 9.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 1.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.2 2.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 1.9 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 5.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.2 4.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2 2.0 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.2 6.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 0.9 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.1 3.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 2.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 2.9 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 1.7 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 2.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 2.6 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 2.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 3.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.9 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.1 5.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 13.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 1.0 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.0 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 1.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.6 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 1.0 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 2.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.6 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects