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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for VSX1

Z-value: 1.23

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Transcription factors associated with VSX1

Gene Symbol Gene ID Gene Info
VSX1
ENSG00000100987.10 visual system homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
VSX1hg19_v2_chr20_-_25062767_25062779-0.371.5e-08Click!

Activity profile of VSX1 motif

Sorted Z-values of VSX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_64673630 32.29 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
KIAA0101
chr19_+_50180317 30.16 ENST00000534465.1
PRMT1
protein arginine methyltransferase 1
chr1_+_154947148 28.36 ENST00000368436.1
ENST00000308987.5
CKS1B
CDC28 protein kinase regulatory subunit 1B
chr1_+_154947126 26.83 ENST00000368439.1
CKS1B
CDC28 protein kinase regulatory subunit 1B
chr1_-_197115818 26.59 ENST00000367409.4
ENST00000294732.7
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr14_+_58711539 24.98 ENST00000216455.4
ENST00000412908.2
ENST00000557508.1
PSMA3
proteasome (prosome, macropain) subunit, alpha type, 3
chr17_+_1733276 24.60 ENST00000254719.5
RPA1
replication protein A1, 70kDa
chr7_-_99699538 23.13 ENST00000343023.6
ENST00000303887.5
MCM7
minichromosome maintenance complex component 7
chr5_+_33440802 22.91 ENST00000502553.1
ENST00000514259.1
ENST00000265112.3
TARS
threonyl-tRNA synthetase
chr15_-_91537723 22.90 ENST00000394249.3
ENST00000559811.1
ENST00000442656.2
ENST00000557905.1
ENST00000361919.3
PRC1
protein regulator of cytokinesis 1
chrX_+_19373700 22.72 ENST00000379804.1
PDHA1
pyruvate dehydrogenase (lipoamide) alpha 1
chr5_+_177631523 22.45 ENST00000506339.1
ENST00000355836.5
ENST00000514633.1
ENST00000515193.1
ENST00000506259.1
ENST00000504898.1
HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr5_+_33441053 22.35 ENST00000541634.1
ENST00000455217.2
ENST00000414361.2
TARS
threonyl-tRNA synthetase
chr20_+_44441304 21.45 ENST00000352551.5
UBE2C
ubiquitin-conjugating enzyme E2C
chr5_+_177631497 21.02 ENST00000358344.3
HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr20_+_44441215 20.59 ENST00000356455.4
ENST00000405520.1
UBE2C
ubiquitin-conjugating enzyme E2C
chr5_+_44809027 19.89 ENST00000507110.1
MRPS30
mitochondrial ribosomal protein S30
chr18_-_33702078 19.40 ENST00000586829.1
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr18_-_33709268 18.83 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr2_-_153574480 18.12 ENST00000410080.1
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr19_+_50180409 18.01 ENST00000391851.4
PRMT1
protein arginine methyltransferase 1
chr19_+_50180507 17.25 ENST00000454376.2
ENST00000524771.1
PRMT1
protein arginine methyltransferase 1
chrX_-_151999269 17.18 ENST00000370277.3
CETN2
centrin, EF-hand protein, 2
chr1_-_149900122 17.06 ENST00000271628.8
SF3B4
splicing factor 3b, subunit 4, 49kDa
chr2_-_70520539 16.86 ENST00000482975.2
ENST00000438261.1
SNRPG
small nuclear ribonucleoprotein polypeptide G
chr2_-_70520832 16.81 ENST00000454893.1
ENST00000272348.2
SNRPG
small nuclear ribonucleoprotein polypeptide G
chr15_+_80351910 16.72 ENST00000261749.6
ENST00000561060.1
ZFAND6
zinc finger, AN1-type domain 6
chr2_-_10952832 16.27 ENST00000540494.1
PDIA6
protein disulfide isomerase family A, member 6
chr12_-_49075941 16.19 ENST00000553086.1
ENST00000548304.1
KANSL2
KAT8 regulatory NSL complex subunit 2
chr7_-_86849883 16.19 ENST00000433078.1
TMEM243
transmembrane protein 243, mitochondrial
chr14_-_74960030 16.11 ENST00000553490.1
ENST00000557510.1
NPC2
Niemann-Pick disease, type C2
chr14_-_74959978 16.05 ENST00000541064.1
NPC2
Niemann-Pick disease, type C2
chr19_-_46195029 15.76 ENST00000588599.1
ENST00000585392.1
ENST00000590212.1
ENST00000587367.1
ENST00000391932.3
SNRPD2
small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
chr7_+_77428149 15.67 ENST00000415251.2
ENST00000275575.7
PHTF2
putative homeodomain transcription factor 2
chr14_-_74959994 15.51 ENST00000238633.2
ENST00000434013.2
NPC2
Niemann-Pick disease, type C2
chr7_+_12727250 15.44 ENST00000404894.1
ARL4A
ADP-ribosylation factor-like 4A
chr17_-_47785504 15.43 ENST00000514907.1
ENST00000503334.1
ENST00000508520.1
SLC35B1
solute carrier family 35, member B1
chrX_+_70503037 15.18 ENST00000535149.1
NONO
non-POU domain containing, octamer-binding
chr17_-_5322786 15.00 ENST00000225696.4
NUP88
nucleoporin 88kDa
chr22_+_24309089 14.94 ENST00000215770.5
DDTL
D-dopachrome tautomerase-like
chr2_-_10952922 14.90 ENST00000272227.3
PDIA6
protein disulfide isomerase family A, member 6
chr17_-_5323480 14.72 ENST00000573584.1
NUP88
nucleoporin 88kDa
chr7_-_137686791 14.41 ENST00000452463.1
ENST00000330387.6
ENST00000456390.1
CREB3L2
cAMP responsive element binding protein 3-like 2
chr7_-_44613494 14.35 ENST00000431640.1
ENST00000258772.5
DDX56
DEAD (Asp-Glu-Ala-Asp) box helicase 56
chr5_+_151151504 14.28 ENST00000356245.3
ENST00000507878.2
G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr5_+_151151471 13.88 ENST00000394123.3
ENST00000543466.1
G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr13_-_50367057 13.51 ENST00000261667.3
KPNA3
karyopherin alpha 3 (importin alpha 4)
chr2_+_65454926 13.51 ENST00000542850.1
ENST00000377982.4
ACTR2
ARP2 actin-related protein 2 homolog (yeast)
chr7_-_148725733 12.70 ENST00000286091.4
PDIA4
protein disulfide isomerase family A, member 4
chr1_-_167905225 12.61 ENST00000367846.4
MPC2
mitochondrial pyruvate carrier 2
chr15_-_64673665 12.51 ENST00000300035.4
KIAA0101
KIAA0101
chr2_-_175113088 12.47 ENST00000409546.1
ENST00000428402.2
OLA1
Obg-like ATPase 1
chr2_-_175113301 12.18 ENST00000344357.5
ENST00000284719.3
OLA1
Obg-like ATPase 1
chr22_-_24316648 11.89 ENST00000403754.3
ENST00000430101.2
ENST00000398344.4
DDT
D-dopachrome tautomerase
chr15_+_80351977 11.89 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
ZFAND6
zinc finger, AN1-type domain 6
chr11_-_66056596 11.86 ENST00000471387.2
ENST00000359461.6
ENST00000376901.4
YIF1A
Yip1 interacting factor homolog A (S. cerevisiae)
chr1_-_150669500 11.74 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr4_-_143227088 11.70 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chrX_-_16887963 11.66 ENST00000380084.4
RBBP7
retinoblastoma binding protein 7
chr12_+_28410128 11.53 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr15_-_66816853 11.48 ENST00000568588.1
RPL4
ribosomal protein L4
chr12_-_56694142 11.30 ENST00000550655.1
ENST00000548567.1
ENST00000551430.2
ENST00000351328.3
CS
citrate synthase
chr17_-_47785265 11.29 ENST00000511763.1
ENST00000515850.1
ENST00000415270.2
ENST00000240333.6
SLC35B1
solute carrier family 35, member B1
chr3_+_179280668 11.22 ENST00000429709.2
ENST00000450518.2
ENST00000392662.1
ENST00000490364.1
ACTL6A
actin-like 6A
chr2_-_61697862 10.97 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr12_-_49076002 10.95 ENST00000357861.3
ENST00000550347.1
ENST00000420613.2
ENST00000550931.1
ENST00000550870.1
KANSL2
KAT8 regulatory NSL complex subunit 2
chr1_-_85742773 10.89 ENST00000370580.1
BCL10
B-cell CLL/lymphoma 10
chr16_+_69458537 10.89 ENST00000515314.1
ENST00000561792.1
ENST00000568237.1
CYB5B
cytochrome b5 type B (outer mitochondrial membrane)
chr4_+_147096837 10.89 ENST00000296581.5
ENST00000502781.1
LSM6
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr7_+_6048856 10.55 ENST00000223029.3
ENST00000400479.2
ENST00000395236.2
AIMP2
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chrX_+_154444643 10.53 ENST00000286428.5
VBP1
von Hippel-Lindau binding protein 1
chr18_-_71959159 10.52 ENST00000494131.2
ENST00000397914.4
ENST00000340533.4
CYB5A
cytochrome b5 type A (microsomal)
chr7_+_77428066 10.13 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
PHTF2
putative homeodomain transcription factor 2
chrX_+_70503433 10.08 ENST00000276079.8
ENST00000373856.3
ENST00000373841.1
ENST00000420903.1
NONO
non-POU domain containing, octamer-binding
chr12_-_6960407 10.02 ENST00000540683.1
ENST00000229265.6
ENST00000535406.1
ENST00000422785.3
CDCA3
cell division cycle associated 3
chrX_+_151999511 9.96 ENST00000370274.3
ENST00000440023.1
ENST00000432467.1
NSDHL
NAD(P) dependent steroid dehydrogenase-like
chr15_-_37393406 9.76 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr19_+_54619125 9.33 ENST00000445811.1
ENST00000419967.1
ENST00000445124.1
ENST00000447810.1
PRPF31
pre-mRNA processing factor 31
chr3_+_138340049 9.27 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr11_+_63754294 8.79 ENST00000543988.1
OTUB1
OTU domain, ubiquitin aldehyde binding 1
chr5_+_145826867 8.62 ENST00000296702.5
ENST00000394421.2
TCERG1
transcription elongation regulator 1
chr4_+_166248775 8.59 ENST00000261507.6
ENST00000507013.1
ENST00000393766.2
ENST00000504317.1
MSMO1
methylsterol monooxygenase 1
chr1_+_43148059 8.56 ENST00000321358.7
ENST00000332220.6
YBX1
Y box binding protein 1
chr6_+_160211481 8.54 ENST00000367034.4
MRPL18
mitochondrial ribosomal protein L18
chr2_+_131100423 8.44 ENST00000409935.1
ENST00000409649.1
ENST00000428740.1
IMP4
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr2_-_86422523 8.39 ENST00000442664.2
ENST00000409051.2
ENST00000449247.2
IMMT
inner membrane protein, mitochondrial
chr10_-_1095050 8.37 ENST00000381344.3
IDI1
isopentenyl-diphosphate delta isomerase 1
chr14_+_23790690 8.30 ENST00000556821.1
PABPN1
poly(A) binding protein, nuclear 1
chr19_+_13049413 8.27 ENST00000316448.5
ENST00000588454.1
CALR
calreticulin
chr19_+_45394477 8.27 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr3_-_52567792 8.19 ENST00000307092.4
ENST00000422318.2
ENST00000459839.1
NT5DC2
5'-nucleotidase domain containing 2
chr11_+_57480046 8.09 ENST00000378312.4
ENST00000278422.4
TMX2
thioredoxin-related transmembrane protein 2
chr20_+_36322408 8.02 ENST00000361383.6
ENST00000447935.1
ENST00000405275.2
CTNNBL1
catenin, beta like 1
chr19_+_19303720 8.01 ENST00000392324.4
RFXANK
regulatory factor X-associated ankyrin-containing protein
chr11_+_67798363 7.97 ENST00000525628.1
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr5_+_159436120 7.93 ENST00000522793.1
ENST00000231238.5
TTC1
tetratricopeptide repeat domain 1
chr19_+_17420340 7.91 ENST00000359866.4
DDA1
DET1 and DDB1 associated 1
chr11_-_3818932 7.75 ENST00000324932.7
ENST00000359171.4
NUP98
nucleoporin 98kDa
chr2_-_69664586 7.70 ENST00000303698.3
ENST00000394305.1
ENST00000410022.2
NFU1
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr4_-_143226979 7.53 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr7_+_55433131 7.53 ENST00000254770.2
LANCL2
LanC lantibiotic synthetase component C-like 2 (bacterial)
chr1_-_35658736 7.43 ENST00000357214.5
SFPQ
splicing factor proline/glutamine-rich
chr15_-_77363441 7.42 ENST00000346495.2
ENST00000424443.3
ENST00000561277.1
TSPAN3
tetraspanin 3
chr2_-_96874553 7.42 ENST00000337288.5
ENST00000443962.1
STARD7
StAR-related lipid transfer (START) domain containing 7
chr10_+_85899196 7.41 ENST00000372134.3
GHITM
growth hormone inducible transmembrane protein
chr17_-_7307358 7.37 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
TMEM256
TMEM256-PLSCR3
transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chr6_+_30687978 7.36 ENST00000327892.8
ENST00000435534.1
TUBB
tubulin, beta class I
chr13_-_41593425 7.36 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr1_-_23670813 7.26 ENST00000374612.1
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chr17_+_79650962 7.20 ENST00000329138.4
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr10_+_70661014 7.19 ENST00000373585.3
DDX50
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr1_-_23670817 7.19 ENST00000478691.1
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chr1_+_24286287 7.14 ENST00000334351.7
ENST00000374468.1
PNRC2
proline-rich nuclear receptor coactivator 2
chr17_+_8191815 7.13 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RANGRF
RAN guanine nucleotide release factor
chr14_-_34931458 7.11 ENST00000298130.4
SPTSSA
serine palmitoyltransferase, small subunit A
chr12_+_98909351 7.09 ENST00000343315.5
ENST00000266732.4
ENST00000393053.2
TMPO
thymopoietin
chr9_+_140135665 7.01 ENST00000340384.4
TUBB4B
tubulin, beta 4B class IVb
chr11_-_3818688 6.96 ENST00000355260.3
ENST00000397004.4
ENST00000397007.4
ENST00000532475.1
NUP98
nucleoporin 98kDa
chr5_+_179125907 6.95 ENST00000247461.4
ENST00000452673.2
ENST00000502498.1
ENST00000507307.1
ENST00000513246.1
ENST00000502673.1
ENST00000506654.1
ENST00000512607.2
ENST00000510810.1
CANX
calnexin
chr4_+_1283639 6.93 ENST00000303400.4
ENST00000505177.2
ENST00000503653.1
ENST00000264750.6
ENST00000502558.1
ENST00000452175.2
ENST00000514708.1
MAEA
macrophage erythroblast attacher
chr19_+_19303572 6.82 ENST00000407360.3
ENST00000540981.1
RFXANK
regulatory factor X-associated ankyrin-containing protein
chr1_-_20987851 6.78 ENST00000464364.1
ENST00000602624.2
DDOST
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr1_-_154946825 6.71 ENST00000368453.4
ENST00000368450.1
ENST00000366442.2
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr14_-_78083112 6.55 ENST00000216484.2
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr1_-_20987889 6.52 ENST00000415136.2
DDOST
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr9_+_12693336 6.51 ENST00000381137.2
ENST00000388918.5
TYRP1
tyrosinase-related protein 1
chr16_-_11036300 6.44 ENST00000331808.4
DEXI
Dexi homolog (mouse)
chr6_-_111927062 6.43 ENST00000359831.4
TRAF3IP2
TRAF3 interacting protein 2
chr19_+_19496624 6.36 ENST00000494516.2
ENST00000360315.3
ENST00000252577.5
GATAD2A
GATA zinc finger domain containing 2A
chr16_+_69458428 6.33 ENST00000512062.1
ENST00000307892.8
CYB5B
cytochrome b5 type B (outer mitochondrial membrane)
chr3_-_33481835 6.33 ENST00000283629.3
UBP1
upstream binding protein 1 (LBP-1a)
chr12_+_21654714 6.22 ENST00000542038.1
ENST00000540141.1
ENST00000229314.5
GOLT1B
golgi transport 1B
chr11_+_95523621 6.21 ENST00000325542.5
ENST00000325486.5
ENST00000544522.1
ENST00000541365.1
CEP57
centrosomal protein 57kDa
chr12_-_6961050 6.14 ENST00000538862.2
CDCA3
cell division cycle associated 3
chr7_-_25019760 6.10 ENST00000352860.1
ENST00000353930.1
ENST00000431825.2
ENST00000313367.2
OSBPL3
oxysterol binding protein-like 3
chr13_+_103249322 6.07 ENST00000376065.4
ENST00000376052.3
TPP2
tripeptidyl peptidase II
chr15_-_77363513 6.03 ENST00000267970.4
TSPAN3
tetraspanin 3
chr19_-_13227463 6.03 ENST00000437766.1
ENST00000221504.8
TRMT1
tRNA methyltransferase 1 homolog (S. cerevisiae)
chr16_+_68119247 5.99 ENST00000575270.1
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr2_-_201828356 5.96 ENST00000234296.2
ORC2
origin recognition complex, subunit 2
chr19_+_16222439 5.94 ENST00000300935.3
RAB8A
RAB8A, member RAS oncogene family
chr6_+_32146131 5.92 ENST00000375094.3
RNF5
ring finger protein 5, E3 ubiquitin protein ligase
chr11_+_67798114 5.84 ENST00000453471.2
ENST00000528492.1
ENST00000526339.1
ENST00000525419.1
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr10_-_126107482 5.83 ENST00000368845.5
ENST00000539214.1
OAT
ornithine aminotransferase
chr22_-_42486747 5.71 ENST00000602404.1
NDUFA6
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa
chr15_-_77363375 5.67 ENST00000559494.1
TSPAN3
tetraspanin 3
chr19_-_13227534 5.62 ENST00000588229.1
ENST00000357720.4
TRMT1
tRNA methyltransferase 1 homolog (S. cerevisiae)
chr4_-_105416039 5.61 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr15_+_89631381 5.58 ENST00000352732.5
ABHD2
abhydrolase domain containing 2
chr11_+_67798090 5.51 ENST00000313468.5
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chrX_-_77150985 5.51 ENST00000358075.6
MAGT1
magnesium transporter 1
chr17_-_74733404 5.45 ENST00000508921.3
ENST00000583836.1
ENST00000358156.6
ENST00000392485.2
ENST00000359995.5
SRSF2
serine/arginine-rich splicing factor 2
chr19_+_39421556 5.40 ENST00000407800.2
ENST00000402029.3
MRPS12
mitochondrial ribosomal protein S12
chr2_-_191878874 5.33 ENST00000392322.3
ENST00000392323.2
ENST00000424722.1
ENST00000361099.3
STAT1
signal transducer and activator of transcription 1, 91kDa
chr3_-_165555200 5.32 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr9_-_99801592 5.21 ENST00000259470.5
CTSV
cathepsin V
chr6_+_26199737 5.09 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr14_+_23790655 5.05 ENST00000397276.2
PABPN1
poly(A) binding protein, nuclear 1
chr3_+_120461484 5.00 ENST00000484715.1
ENST00000469772.1
ENST00000283875.5
ENST00000492959.1
GTF2E1
general transcription factor IIE, polypeptide 1, alpha 56kDa
chr19_-_47616992 4.98 ENST00000253048.5
ZC3H4
zinc finger CCCH-type containing 4
chr4_+_169013666 4.91 ENST00000359299.3
ANXA10
annexin A10
chr16_+_69345243 4.87 ENST00000254950.11
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr22_-_32651326 4.80 ENST00000266086.4
SLC5A4
solute carrier family 5 (glucose activated ion channel), member 4
chr15_-_43802769 4.51 ENST00000263801.3
TP53BP1
tumor protein p53 binding protein 1
chr1_-_20987982 4.50 ENST00000375048.3
DDOST
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr15_+_41523335 4.47 ENST00000334660.5
CHP1
calcineurin-like EF-hand protein 1
chr3_-_119813264 4.41 ENST00000264235.8
GSK3B
glycogen synthase kinase 3 beta
chr22_-_30960876 4.32 ENST00000401975.1
ENST00000428682.1
ENST00000423299.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr6_+_33172407 4.25 ENST00000374662.3
HSD17B8
hydroxysteroid (17-beta) dehydrogenase 8
chr1_-_23670752 4.25 ENST00000302271.6
ENST00000426846.2
ENST00000427764.2
ENST00000606561.1
ENST00000374616.3
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chr3_-_195538760 4.21 ENST00000475231.1
MUC4
mucin 4, cell surface associated
chr8_+_120428546 4.21 ENST00000259526.3
NOV
nephroblastoma overexpressed
chr7_+_138145145 4.11 ENST00000415680.2
TRIM24
tripartite motif containing 24
chr1_-_47655686 4.08 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr4_-_39979576 4.05 ENST00000303538.8
ENST00000503396.1
PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr10_+_1095416 4.03 ENST00000358220.1
WDR37
WD repeat domain 37
chr2_+_162087577 3.97 ENST00000439442.1
TANK
TRAF family member-associated NFKB activator
chr12_-_21654479 3.94 ENST00000421138.2
ENST00000444129.2
ENST00000539672.1
ENST00000542432.1
ENST00000536964.1
ENST00000536240.1
ENST00000396093.3
ENST00000314748.6
RECQL
RecQ protein-like (DNA helicase Q1-like)
chr5_+_179125368 3.85 ENST00000502296.1
ENST00000504734.1
ENST00000415618.2
CANX
calnexin
chrX_-_15872914 3.84 ENST00000380291.1
ENST00000545766.1
ENST00000421527.2
ENST00000329235.2
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr16_+_68279207 3.83 ENST00000413021.2
ENST00000565744.1
ENST00000219345.5
PLA2G15
phospholipase A2, group XV
chr9_+_34646624 3.80 ENST00000450095.2
ENST00000556278.1
GALT
GALT
galactose-1-phosphate uridylyltransferase
Uncharacterized protein
chr2_-_192711968 3.78 ENST00000304141.4
SDPR
serum deprivation response
chr10_-_127505167 3.78 ENST00000368786.1
UROS
uroporphyrinogen III synthase
chr17_+_46970134 3.75 ENST00000503641.1
ENST00000514808.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr3_-_105588231 3.72 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr17_+_45727204 3.70 ENST00000290158.4
KPNB1
karyopherin (importin) beta 1
chr11_+_64018955 3.69 ENST00000279230.6
ENST00000540288.1
ENST00000325234.5
PLCB3
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr16_+_46723552 3.66 ENST00000219097.2
ENST00000568364.2
ORC6
origin recognition complex, subunit 6
chr17_-_47841485 3.64 ENST00000506156.1
ENST00000240364.2
FAM117A
family with sequence similarity 117, member A
chr19_+_41770236 3.64 ENST00000392006.3
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr11_-_122932730 3.63 ENST00000532182.1
ENST00000524590.1
ENST00000528292.1
ENST00000533540.1
ENST00000525463.1
HSPA8
heat shock 70kDa protein 8
chr17_-_79980734 3.63 ENST00000584600.1
ENST00000584347.1
ENST00000580435.1
ENST00000306704.6
ENST00000392359.3
STRA13
stimulated by retinoic acid 13
chr12_+_3000037 3.57 ENST00000544943.1
ENST00000448120.2
TULP3
tubby like protein 3
chr15_-_43785303 3.52 ENST00000382039.3
ENST00000450115.2
ENST00000382044.4
TP53BP1
tumor protein p53 binding protein 1
chr2_+_234637754 3.50 ENST00000482026.1
ENST00000609767.1
UGT1A3
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A3
UDP glucuronosyltransferase 1 family, polypeptide A8
chr1_+_167905894 3.46 ENST00000367843.3
ENST00000432587.2
ENST00000312263.6
DCAF6
DDB1 and CUL4 associated factor 6
chr15_+_89631647 3.43 ENST00000569550.1
ENST00000565066.1
ENST00000565973.1
ABHD2
abhydrolase domain containing 2
chr3_+_179322481 3.38 ENST00000259037.3
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr11_+_3819049 3.37 ENST00000396986.2
ENST00000300730.6
ENST00000532535.1
ENST00000396993.4
ENST00000396991.2
ENST00000532523.1
ENST00000459679.1
ENST00000464261.1
ENST00000464906.2
ENST00000464441.1
PGAP2
post-GPI attachment to proteins 2

Network of associatons between targets according to the STRING database.

First level regulatory network of VSX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
15.1 45.3 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
11.9 47.7 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
10.9 65.4 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
8.9 26.7 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
5.3 42.0 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) positive regulation of exit from mitosis(GO:0031536)
5.1 25.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
4.5 13.5 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
4.4 13.3 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
4.2 29.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
3.9 35.3 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
3.8 38.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
3.6 10.9 GO:0032765 lymphotoxin A production(GO:0032641) positive regulation of mast cell cytokine production(GO:0032765) lymphotoxin A biosynthetic process(GO:0042109)
3.5 10.6 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
3.3 26.6 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
2.9 14.7 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
2.8 8.5 GO:0035928 rRNA import into mitochondrion(GO:0035928)
2.3 23.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.9 5.7 GO:0006258 UDP-glucose catabolic process(GO:0006258) galactose catabolic process via UDP-galactose(GO:0033499)
1.8 27.1 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
1.8 7.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
1.8 5.3 GO:0014016 neuroblast differentiation(GO:0014016)
1.6 6.5 GO:1904502 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
1.6 4.9 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878) ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
1.6 9.3 GO:0048254 snoRNA localization(GO:0048254)
1.5 10.6 GO:1900045 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
1.5 13.3 GO:1901419 regulation of response to alcohol(GO:1901419)
1.5 4.4 GO:0071109 superior temporal gyrus development(GO:0071109)
1.4 5.7 GO:0031291 Ran protein signal transduction(GO:0031291)
1.4 4.2 GO:1990523 bone regeneration(GO:1990523)
1.4 8.3 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
1.3 22.9 GO:0000022 mitotic spindle elongation(GO:0000022)
1.3 5.3 GO:2000697 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
1.3 6.3 GO:0061738 late endosomal microautophagy(GO:0061738) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
1.2 7.4 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
1.2 8.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
1.2 17.1 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
1.2 3.7 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
1.1 55.2 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
1.1 28.6 GO:0006625 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
1.1 3.2 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
1.1 2.1 GO:0060434 bronchus morphogenesis(GO:0060434)
1.1 49.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
1.0 41.8 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
1.0 5.2 GO:1990834 response to odorant(GO:1990834)
1.0 8.0 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
1.0 6.9 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
1.0 5.8 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
1.0 11.5 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.9 3.8 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.9 2.8 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.9 7.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.9 0.9 GO:1903179 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
0.8 10.5 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.8 10.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.8 2.3 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.8 19.1 GO:0061157 mRNA destabilization(GO:0061157)
0.7 6.5 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.7 1.4 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.7 3.5 GO:0070980 biphenyl catabolic process(GO:0070980)
0.7 5.5 GO:0015693 magnesium ion transport(GO:0015693)
0.7 4.0 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.7 5.3 GO:0070885 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.6 32.1 GO:0032508 DNA duplex unwinding(GO:0032508)
0.6 2.5 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.6 3.7 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.6 13.5 GO:0019054 modulation by virus of host process(GO:0019054)
0.6 10.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.6 7.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.6 8.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.5 21.5 GO:0042407 cristae formation(GO:0042407)
0.5 44.0 GO:0045454 cell redox homeostasis(GO:0045454)
0.5 11.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.5 4.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.5 11.0 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.5 10.0 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.5 5.2 GO:0048194 Golgi vesicle budding(GO:0048194)
0.5 11.9 GO:0042438 melanin biosynthetic process(GO:0042438)
0.5 2.3 GO:0048733 sebaceous gland development(GO:0048733)
0.5 1.4 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.4 7.2 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.4 11.6 GO:0030488 tRNA methylation(GO:0030488)
0.4 11.7 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.4 8.5 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.4 7.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.4 5.9 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.4 7.7 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.3 25.3 GO:0070125 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.3 6.2 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.3 10.9 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.3 1.7 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.3 17.8 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.3 21.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.3 5.9 GO:0098969 neurotransmitter receptor transport to plasma membrane(GO:0098877) neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540)
0.3 4.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.3 7.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.3 9.6 GO:0006270 DNA replication initiation(GO:0006270)
0.3 5.4 GO:0033197 response to vitamin E(GO:0033197)
0.3 7.0 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.3 0.3 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.3 25.6 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436)
0.3 3.8 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.2 1.5 GO:0016584 nucleosome positioning(GO:0016584)
0.2 14.4 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.2 9.0 GO:0007340 acrosome reaction(GO:0007340)
0.2 9.2 GO:0050873 brown fat cell differentiation(GO:0050873)
0.2 2.3 GO:0009642 response to light intensity(GO:0009642)
0.2 16.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.2 6.2 GO:0034453 microtubule anchoring(GO:0034453)
0.2 0.6 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.2 13.9 GO:0032465 regulation of cytokinesis(GO:0032465)
0.2 0.7 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.2 27.1 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.2 7.1 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.2 6.1 GO:0000209 protein polyubiquitination(GO:0000209)
0.1 4.0 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 1.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 1.9 GO:0007097 nuclear migration(GO:0007097)
0.1 6.7 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 0.8 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 34.2 GO:0006364 rRNA processing(GO:0006364)
0.1 0.9 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.1 9.8 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.1 6.7 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.4 GO:0061743 motor learning(GO:0061743)
0.1 1.5 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 3.2 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 1.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 17.2 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.1 2.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 3.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 3.7 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.1 3.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 7.3 GO:0002062 chondrocyte differentiation(GO:0002062)
0.1 0.8 GO:0016180 snRNA processing(GO:0016180)
0.1 0.5 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.1 4.2 GO:0016445 somatic diversification of immunoglobulins(GO:0016445)
0.1 1.5 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 2.0 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 2.0 GO:0006397 mRNA processing(GO:0006397)
0.0 3.1 GO:0042246 tissue regeneration(GO:0042246)
0.0 6.3 GO:0019079 viral genome replication(GO:0019079)
0.0 0.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.5 GO:0006342 chromatin silencing(GO:0006342)
0.0 11.9 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 5.1 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.8 GO:0019228 neuronal action potential(GO:0019228)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
6.4 114.9 GO:0034709 methylosome(GO:0034709)
4.1 32.7 GO:0042382 paraspeckles(GO:0042382)
3.8 26.6 GO:0036449 microtubule minus-end(GO:0036449)
3.4 13.7 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
3.0 29.8 GO:0070938 contractile ring(GO:0070938)
2.5 14.7 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
2.4 7.2 GO:0033565 ESCRT-0 complex(GO:0033565)
2.2 10.9 GO:0032449 CBM complex(GO:0032449) lipopolysaccharide receptor complex(GO:0046696)
2.1 25.0 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
2.0 6.0 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
1.9 23.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
1.8 34.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
1.8 23.1 GO:0042555 MCM complex(GO:0042555)
1.8 24.6 GO:0005662 DNA replication factor A complex(GO:0005662)
1.7 8.4 GO:0034457 Mpp10 complex(GO:0034457)
1.6 10.9 GO:0005688 U6 snRNP(GO:0005688)
1.5 25.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
1.5 10.5 GO:0016272 prefoldin complex(GO:0016272)
1.5 14.6 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
1.4 42.6 GO:0005680 anaphase-promoting complex(GO:0005680)
1.4 5.4 GO:0035061 interchromatin granule(GO:0035061)
1.3 18.1 GO:0071004 U2-type prespliceosome(GO:0071004)
1.2 8.4 GO:0061617 MICOS complex(GO:0061617)
1.2 8.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
1.2 9.3 GO:0005687 U4 snRNP(GO:0005687)
1.1 5.7 GO:0005726 perichromatin fibrils(GO:0005726)
1.1 6.7 GO:0070435 Shc-EGFR complex(GO:0070435)
1.1 13.3 GO:0042405 nuclear inclusion body(GO:0042405)
1.1 10.8 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
1.1 17.2 GO:0000109 nucleotide-excision repair complex(GO:0000109)
1.0 8.3 GO:0042824 MHC class I peptide loading complex(GO:0042824)
1.0 38.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
1.0 55.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
1.0 38.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.9 12.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.9 13.5 GO:0030478 actin cap(GO:0030478)
0.9 6.3 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.8 2.5 GO:0035189 Rb-E2F complex(GO:0035189)
0.7 9.0 GO:0097524 sperm plasma membrane(GO:0097524)
0.7 4.0 GO:0070545 PeBoW complex(GO:0070545)
0.6 10.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.6 16.6 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.5 5.9 GO:0000974 Prp19 complex(GO:0000974)
0.5 49.0 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.5 52.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.5 10.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.5 10.3 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.5 4.9 GO:0090543 Flemming body(GO:0090543)
0.5 5.0 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.4 28.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.4 3.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.4 6.5 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.4 8.0 GO:0035861 site of double-strand break(GO:0035861)
0.4 4.4 GO:1990909 Wnt signalosome(GO:1990909)
0.4 3.7 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.4 1.4 GO:1990075 periciliary membrane compartment(GO:1990075)
0.4 2.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.3 6.1 GO:0097038 filopodium tip(GO:0032433) perinuclear endoplasmic reticulum(GO:0097038)
0.3 21.0 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.3 0.9 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.3 1.9 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.2 25.1 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.2 1.7 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.2 22.6 GO:0005783 endoplasmic reticulum(GO:0005783)
0.2 11.5 GO:0005802 trans-Golgi network(GO:0005802)
0.2 5.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2 8.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 0.8 GO:0070876 SOSS complex(GO:0070876)
0.2 3.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 3.7 GO:0001891 phagocytic cup(GO:0001891)
0.2 5.9 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.2 9.8 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 1.5 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 10.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 10.0 GO:0005811 lipid particle(GO:0005811)
0.1 4.2 GO:0005921 gap junction(GO:0005921)
0.1 16.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 1.4 GO:0042587 glycogen granule(GO:0042587)
0.1 28.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 2.5 GO:0030056 hemidesmosome(GO:0030056)
0.1 7.9 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 5.9 GO:0045171 intercellular bridge(GO:0045171)
0.1 12.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 16.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 7.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 0.9 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 27.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 1.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 5.2 GO:0043202 lysosomal lumen(GO:0043202)
0.1 1.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 7.3 GO:0005796 Golgi lumen(GO:0005796)
0.1 3.8 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 1.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 4.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 2.3 GO:0045095 keratin filament(GO:0045095)
0.1 6.9 GO:0030426 growth cone(GO:0030426)
0.0 26.5 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 4.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 4.3 GO:0005740 mitochondrial envelope(GO:0005740)
0.0 2.0 GO:0001772 immunological synapse(GO:0001772)
0.0 2.3 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 2.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
15.1 45.3 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
10.9 65.4 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
8.9 26.7 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
7.9 55.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
5.7 22.7 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
4.6 13.7 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
3.8 19.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
3.4 17.2 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
3.3 10.0 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
3.0 11.9 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
2.9 11.6 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
2.8 8.4 GO:0042134 rRNA primary transcript binding(GO:0042134)
2.3 23.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
2.3 27.1 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
2.3 11.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
2.2 24.6 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
2.1 43.9 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
2.0 38.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
1.8 7.3 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
1.7 5.2 GO:0030984 kininogen binding(GO:0030984)
1.6 12.6 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
1.3 8.0 GO:0061649 ubiquitinated histone binding(GO:0061649)
1.3 9.3 GO:0030621 U4 snRNA binding(GO:0030621)
1.3 5.3 GO:0003990 acetylcholinesterase activity(GO:0003990)
1.2 55.2 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
1.2 4.8 GO:0005412 glucose:sodium symporter activity(GO:0005412)
1.2 8.3 GO:0001849 complement component C1q binding(GO:0001849)
1.1 10.6 GO:0019784 NEDD8-specific protease activity(GO:0019784)
1.0 7.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
1.0 6.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
1.0 9.8 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
1.0 6.7 GO:0048408 epidermal growth factor binding(GO:0048408)
0.9 2.8 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.9 8.4 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.9 8.3 GO:0015288 porin activity(GO:0015288)
0.9 42.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.9 49.2 GO:0015485 cholesterol binding(GO:0015485)
0.9 34.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.9 4.3 GO:0070404 NADH binding(GO:0070404)
0.8 25.0 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.8 25.5 GO:0070064 proline-rich region binding(GO:0070064)
0.7 8.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.7 9.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.7 14.4 GO:0035497 cAMP response element binding(GO:0035497)
0.7 4.0 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.6 3.7 GO:0047115 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.6 4.3 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.6 8.5 GO:0008097 5S rRNA binding(GO:0008097)
0.6 9.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.6 27.0 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.5 10.8 GO:0034185 apolipoprotein binding(GO:0034185)
0.5 5.7 GO:0034056 estrogen response element binding(GO:0034056)
0.5 5.7 GO:0070569 uridylyltransferase activity(GO:0070569)
0.5 3.1 GO:0043532 angiostatin binding(GO:0043532)
0.5 5.9 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.4 9.4 GO:0043422 protein kinase B binding(GO:0043422)
0.4 10.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.4 3.8 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.4 22.9 GO:0019894 kinesin binding(GO:0019894)
0.4 41.2 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.4 11.4 GO:0042288 MHC class I protein binding(GO:0042288)
0.4 10.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3 14.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.3 5.8 GO:0008483 transaminase activity(GO:0008483)
0.2 3.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.2 6.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.2 0.7 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.2 3.9 GO:0005521 lamin binding(GO:0005521)
0.2 5.9 GO:0031489 myosin V binding(GO:0031489)
0.2 3.7 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.2 6.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 6.3 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.2 38.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 4.4 GO:0050321 protein kinase A catalytic subunit binding(GO:0034236) tau-protein kinase activity(GO:0050321)
0.2 4.2 GO:0005112 Notch binding(GO:0005112)
0.2 8.6 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.2 50.8 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.2 11.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.2 2.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 3.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2 9.9 GO:0070063 RNA polymerase binding(GO:0070063)
0.2 5.3 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.2 10.6 GO:0005507 copper ion binding(GO:0005507)
0.1 1.5 GO:0015643 toxic substance binding(GO:0015643)
0.1 2.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.8 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 0.5 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 3.7 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 14.9 GO:0016829 lyase activity(GO:0016829)
0.1 4.9 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 2.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 13.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 3.5 GO:0001972 retinoic acid binding(GO:0001972)
0.1 4.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 1.5 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 2.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 8.1 GO:0008565 protein transporter activity(GO:0008565)
0.1 5.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.4 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 3.8 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 20.2 GO:0005525 GTP binding(GO:0005525)
0.0 2.1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 3.1 GO:0032947 protein complex scaffold(GO:0032947)
0.0 1.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.8 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 3.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.9 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 3.9 GO:0020037 heme binding(GO:0020037)
0.0 0.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 2.7 GO:0005516 calmodulin binding(GO:0005516)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 25.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.8 47.7 PID ATR PATHWAY ATR signaling pathway
0.6 45.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.5 10.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.4 22.9 PID PLK1 PATHWAY PLK1 signaling events
0.4 22.2 PID AURORA B PATHWAY Aurora B signaling
0.4 5.3 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.3 13.3 PID MYC PATHWAY C-MYC pathway
0.3 60.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.3 14.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.3 13.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 8.0 PID ATM PATHWAY ATM pathway
0.2 5.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.2 12.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.2 8.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.2 8.6 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 5.7 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 9.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 3.7 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 7.4 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 12.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 6.3 PID CMYB PATHWAY C-MYB transcription factor network
0.0 2.5 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.8 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.7 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 38.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
2.1 33.7 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
2.1 24.6 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
1.6 55.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
1.5 42.6 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
1.4 23.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
1.3 19.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
1.1 19.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
1.0 12.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
1.0 13.3 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.9 15.8 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.9 35.5 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.9 80.2 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.9 14.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.7 10.9 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.7 53.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.6 17.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.6 12.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.6 35.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.5 23.9 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.5 15.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.5 10.9 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.4 8.0 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.4 7.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.4 31.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.3 28.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.3 3.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.3 28.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.3 13.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.3 5.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.3 11.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.3 7.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 14.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2 8.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.2 11.1 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.2 5.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 13.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.7 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 4.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 3.5 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 4.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 2.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 11.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 2.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.2 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.7 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 2.6 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 3.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP