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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ZBTB14

Z-value: 2.08

Motif logo

Transcription factors associated with ZBTB14

Gene Symbol Gene ID Gene Info
ENSG00000198081.6 zinc finger and BTB domain containing 14

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB14hg19_v2_chr18_-_5296138_52961940.237.9e-04Click!

Activity profile of ZBTB14 motif

Sorted Z-values of ZBTB14 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_38420623 67.73 ENST00000378482.2
tetraspanin 7
chr16_+_56623433 52.82 ENST00000570176.1
metallothionein 3
chrX_+_38420783 50.50 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
tetraspanin 7
chr4_+_158141843 49.84 ENST00000509417.1
ENST00000296526.7
glutamate receptor, ionotropic, AMPA 2
chr3_-_133614597 49.15 ENST00000285208.4
ENST00000460865.3
RAB6B, member RAS oncogene family
chr1_+_204797749 48.78 ENST00000367172.4
ENST00000367171.4
ENST00000367170.4
ENST00000338515.6
ENST00000339876.6
ENST00000338586.6
ENST00000539706.1
ENST00000360049.4
ENST00000367169.4
ENST00000446412.1
ENST00000403080.1
neurofascin
chr4_+_158141899 48.77 ENST00000264426.9
ENST00000506284.1
glutamate receptor, ionotropic, AMPA 2
chr16_+_2039946 48.65 ENST00000248121.2
ENST00000568896.1
synaptogyrin 3
chr1_+_6845384 48.49 ENST00000303635.7
calmodulin binding transcription activator 1
chr15_+_91643442 47.10 ENST00000394232.1
synaptic vesicle glycoprotein 2B
chr3_-_133614421 45.59 ENST00000543906.1
RAB6B, member RAS oncogene family
chr13_-_36705425 45.34 ENST00000255448.4
ENST00000360631.3
ENST00000379892.4
doublecortin-like kinase 1
chr2_+_17935119 43.87 ENST00000317402.7
GEN1 Holliday junction 5' flap endonuclease
chr16_+_222846 42.33 ENST00000251595.6
ENST00000397806.1
hemoglobin, alpha 2
chr4_+_158141806 41.06 ENST00000393815.2
glutamate receptor, ionotropic, AMPA 2
chr11_-_6440283 37.63 ENST00000299402.6
ENST00000609360.1
ENST00000389906.2
ENST00000532020.2
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr8_+_24772455 35.81 ENST00000433454.2
neurofilament, medium polypeptide
chr1_-_9884011 33.31 ENST00000361311.4
calsyntenin 1
chr11_-_125366089 33.28 ENST00000366139.3
ENST00000278919.3
fasciculation and elongation protein zeta 1 (zygin I)
chr17_+_43971643 32.56 ENST00000344290.5
ENST00000262410.5
ENST00000351559.5
ENST00000340799.5
ENST00000535772.1
ENST00000347967.5
microtubule-associated protein tau
chr17_+_43972010 31.66 ENST00000334239.8
ENST00000446361.3
microtubule-associated protein tau
chr7_+_45613958 30.69 ENST00000297323.7
adenylate cyclase 1 (brain)
chr16_+_226658 29.85 ENST00000320868.5
ENST00000397797.1
hemoglobin, alpha 1
chr11_-_6440624 29.47 ENST00000311051.3
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr9_+_17579084 29.40 ENST00000380607.4
SH3-domain GRB2-like 2
chr17_-_42277203 28.77 ENST00000587097.1
ataxin 7-like 3
chr2_-_175869936 27.50 ENST00000409900.3
chimerin 1
chr12_+_121078355 27.39 ENST00000316803.3
calcium binding protein 1
chr17_+_44668035 26.64 ENST00000398238.4
ENST00000225282.8
N-ethylmaleimide-sensitive factor
chr12_-_124457257 24.95 ENST00000545891.1
coiled-coil domain containing 92
chrX_+_11776410 24.79 ENST00000361672.2
male-specific lethal 3 homolog (Drosophila)
chr16_+_6533380 24.22 ENST00000552089.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr10_+_105036909 24.00 ENST00000369849.4
internexin neuronal intermediate filament protein, alpha
chr22_-_20104700 23.91 ENST00000439169.2
ENST00000445045.1
ENST00000404751.3
ENST00000252136.7
ENST00000403707.3
tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr2_-_175870085 23.85 ENST00000409156.3
chimerin 1
chr16_+_30710462 23.66 ENST00000262518.4
ENST00000395059.2
ENST00000344771.4
Snf2-related CREBBP activator protein
chr12_-_124457371 22.83 ENST00000238156.3
ENST00000545037.1
coiled-coil domain containing 92
chr6_+_31865552 22.41 ENST00000469372.1
ENST00000497706.1
complement component 2
chr2_+_17935383 22.35 ENST00000524465.1
ENST00000381254.2
ENST00000532257.1
GEN1 Holliday junction 5' flap endonuclease
chr2_+_79740118 21.94 ENST00000496558.1
ENST00000451966.1
catenin (cadherin-associated protein), alpha 2
chr11_+_71791849 21.82 ENST00000423494.2
ENST00000539587.1
ENST00000538478.1
ENST00000324866.7
ENST00000439209.1
leucine rich transmembrane and O-methyltransferase domain containing
chr5_-_11904152 20.81 ENST00000304623.8
ENST00000458100.2
catenin (cadherin-associated protein), delta 2
chr5_-_11904100 20.65 ENST00000359640.2
catenin (cadherin-associated protein), delta 2
chr14_-_23770683 20.63 ENST00000561437.1
ENST00000559942.1
ENST00000560913.1
ENST00000559314.1
ENST00000558058.1
protein phosphatase 1, regulatory subunit 3E
chr19_+_18942761 20.28 ENST00000599848.1
UPF1 regulator of nonsense transcripts homolog (yeast)
chr1_+_1981890 20.27 ENST00000378567.3
ENST00000468310.1
protein kinase C, zeta
chr19_+_35634146 20.02 ENST00000586063.1
ENST00000270310.2
ENST00000588265.1
FXYD domain containing ion transport regulator 7
chr19_+_35521572 19.75 ENST00000262631.5
sodium channel, voltage-gated, type I, beta subunit
chr15_+_75287861 19.68 ENST00000425597.3
ENST00000562327.1
ENST00000568018.1
ENST00000562212.1
ENST00000567920.1
ENST00000566872.1
ENST00000361900.6
ENST00000545456.1
secretory carrier membrane protein 5
chr6_-_33285505 19.65 ENST00000431845.2
zinc finger and BTB domain containing 22
chr11_+_71791693 19.47 ENST00000289488.2
ENST00000447974.1
leucine rich transmembrane and O-methyltransferase domain containing
chr20_+_44657845 19.45 ENST00000243964.3
solute carrier family 12 (potassium/chloride transporter), member 5
chr19_-_19006890 19.26 ENST00000247005.6
growth differentiation factor 1
chr19_+_35521616 19.14 ENST00000595652.1
sodium channel, voltage-gated, type I, beta subunit
chr20_+_17207665 18.83 ENST00000536609.1
proprotein convertase subtilisin/kexin type 2
chr16_+_1662326 18.81 ENST00000397412.3
Crm, cramped-like (Drosophila)
chr17_-_79139817 18.60 ENST00000326724.4
apoptosis-associated tyrosine kinase
chr9_+_131314859 18.28 ENST00000358161.5
ENST00000372731.4
ENST00000372739.3
spectrin, alpha, non-erythrocytic 1
chr19_-_7939319 18.24 ENST00000539422.1
Protein FLJ22184
chr9_-_115095883 17.93 ENST00000450374.1
ENST00000374255.2
ENST00000334318.6
ENST00000374257.1
polypyrimidine tract binding protein 3
chr22_-_39239987 17.82 ENST00000333039.2
neuronal pentraxin receptor
chr19_-_46974741 17.78 ENST00000313683.10
ENST00000602246.1
paraneoplastic Ma antigen family-like 1
chr1_-_20812690 17.69 ENST00000375078.3
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr1_-_223537475 17.64 ENST00000344029.6
ENST00000494793.2
ENST00000366878.4
ENST00000366877.3
sushi domain containing 4
chr7_-_44365216 17.48 ENST00000358707.3
ENST00000457475.1
ENST00000440254.2
calcium/calmodulin-dependent protein kinase II beta
chr19_-_19006920 17.43 ENST00000429504.2
ENST00000427170.2
ceramide synthase 1
chr19_-_46974664 17.24 ENST00000438932.2
paraneoplastic Ma antigen family-like 1
chr8_+_142402089 17.13 ENST00000521578.1
ENST00000520105.1
ENST00000523147.1
protein tyrosine phosphatase type IVA, member 3
chr16_+_6533729 17.11 ENST00000551752.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr2_-_86564776 16.52 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
receptor accessory protein 1
chr9_+_6757634 16.46 ENST00000543771.1
ENST00000401787.3
ENST00000381306.3
ENST00000381309.3
lysine (K)-specific demethylase 4C
chr7_-_44365020 16.33 ENST00000395747.2
ENST00000347193.4
ENST00000346990.4
ENST00000258682.6
ENST00000353625.4
ENST00000421607.1
ENST00000424197.1
ENST00000502837.2
ENST00000350811.3
ENST00000395749.2
calcium/calmodulin-dependent protein kinase II beta
chr20_+_20348740 16.16 ENST00000310227.1
insulinoma-associated 1
chr7_+_65338230 16.16 ENST00000360768.3
vitamin K epoxide reductase complex, subunit 1-like 1
chr22_-_45559642 15.78 ENST00000426282.2
CTA-217C2.1
chr16_-_1661988 15.46 ENST00000426508.2
intraflagellar transport 140 homolog (Chlamydomonas)
chr11_-_64410787 15.30 ENST00000301894.2
neurexin 2
chr15_-_71146480 15.29 ENST00000299213.8
La ribonucleoprotein domain family, member 6
chr4_-_5894777 15.22 ENST00000324989.7
collapsin response mediator protein 1
chr19_+_48281803 15.18 ENST00000601048.1
selenoprotein W, 1
chr20_+_17207636 15.17 ENST00000262545.2
proprotein convertase subtilisin/kexin type 2
chr9_-_86571628 15.05 ENST00000376344.3
chromosome 9 open reading frame 64
chr20_-_35492048 15.01 ENST00000237536.4
suppressor of glucose, autophagy associated 1
chr4_+_41258786 14.83 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr1_+_84543734 14.82 ENST00000370689.2
protein kinase, cAMP-dependent, catalytic, beta
chr19_-_11591848 14.80 ENST00000359227.3
ELAV like neuron-specific RNA binding protein 3
chr22_+_39745930 14.79 ENST00000318801.4
ENST00000216155.7
ENST00000406293.3
ENST00000328933.5
synaptogyrin 1
chr14_-_104313824 14.78 ENST00000553739.1
ENST00000202556.9
protein phosphatase 1, regulatory subunit 13B
chr14_-_93651186 14.74 ENST00000556883.1
ENST00000298894.4
modulator of apoptosis 1
chr17_+_80416482 14.73 ENST00000309794.11
ENST00000345415.7
ENST00000457415.3
ENST00000584411.1
ENST00000412079.2
ENST00000577432.1
nuclear prelamin A recognition factor
chr17_+_53343577 14.71 ENST00000573945.1
hepatic leukemia factor
chr19_+_48281842 14.61 ENST00000509570.2
selenoprotein W, 1
chr12_-_54982300 14.59 ENST00000547431.1
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr17_-_78450398 14.53 ENST00000306773.4
neuronal pentraxin I
chr5_-_88179302 14.53 ENST00000504921.2
myocyte enhancer factor 2C
chr2_-_28113217 14.46 ENST00000444339.2
ribokinase
chr14_+_102027688 14.44 ENST00000510508.4
ENST00000359323.3
deiodinase, iodothyronine, type III
chr11_-_76155618 14.29 ENST00000530759.1
RP11-111M22.3
chr19_+_5904866 14.23 ENST00000339485.3
vimentin-type intermediate filament associated coiled-coil protein
chr3_+_147127142 14.20 ENST00000282928.4
Zic family member 1
chr17_+_40811283 14.16 ENST00000251412.7
tubulin, gamma 2
chr8_-_125740730 14.16 ENST00000354184.4
metastasis suppressor 1
chr11_-_76155700 14.15 ENST00000572035.1
RP11-111M22.3
chr16_+_56225248 14.12 ENST00000262493.6
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr7_+_98246588 14.10 ENST00000265634.3
neuronal pentraxin II
chr9_-_139922631 14.09 ENST00000341511.6
ATP-binding cassette, sub-family A (ABC1), member 2
chr8_-_144242020 14.03 ENST00000414417.2
lymphocyte antigen 6 complex, locus H
chr3_+_49591881 13.97 ENST00000296452.4
bassoon presynaptic cytomatrix protein
chr9_-_139922726 13.81 ENST00000265662.5
ENST00000371605.3
ATP-binding cassette, sub-family A (ABC1), member 2
chr8_+_85095769 13.68 ENST00000518566.1
RALY RNA binding protein-like
chr11_+_17741111 13.59 ENST00000250003.3
myogenic differentiation 1
chr22_+_41777927 13.56 ENST00000266304.4
thyrotrophic embryonic factor
chr6_-_143266297 13.36 ENST00000367603.2
human immunodeficiency virus type I enhancer binding protein 2
chr12_+_13197218 13.23 ENST00000197268.8
KIAA1467
chr17_-_27893990 13.14 ENST00000307201.4
abhydrolase domain containing 15
chr19_+_45596398 13.10 ENST00000544069.2
protein phosphatase 1, regulatory subunit 37
chr8_+_12809093 13.08 ENST00000528753.2
KIAA1456
chr7_+_121513143 12.99 ENST00000393386.2
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr3_+_142838091 12.88 ENST00000309575.3
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
chr22_-_31742218 12.85 ENST00000266269.5
ENST00000405309.3
ENST00000351933.4
POZ (BTB) and AT hook containing zinc finger 1
chr17_-_19771216 12.78 ENST00000395544.4
unc-51 like autophagy activating kinase 2
chr11_-_45687128 12.73 ENST00000308064.2
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr8_-_125740514 12.71 ENST00000325064.5
ENST00000518547.1
metastasis suppressor 1
chr12_+_123717458 12.60 ENST00000253233.1
chromosome 12 open reading frame 65
chr1_-_21948906 12.56 ENST00000374761.2
ENST00000599760.1
RAP1 GTPase activating protein
chr10_-_735553 12.49 ENST00000280886.6
ENST00000423550.1
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr9_+_71320596 12.45 ENST00000265382.3
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr7_-_139876812 12.44 ENST00000397560.2
lysine (K)-specific demethylase 7A
chr20_+_32077880 12.37 ENST00000342704.6
ENST00000375279.2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr12_-_125052010 12.32 ENST00000458234.1
nuclear receptor corepressor 2
chr11_-_134281812 12.28 ENST00000392580.1
ENST00000312527.4
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr3_+_14989186 12.28 ENST00000435454.1
ENST00000323373.6
nuclear receptor subfamily 2, group C, member 2
chr8_-_144241432 12.20 ENST00000430474.2
lymphocyte antigen 6 complex, locus H
chr15_-_58357866 12.15 ENST00000537372.1
aldehyde dehydrogenase 1 family, member A2
chr12_-_48551366 12.12 ENST00000535988.1
ENST00000536953.1
ENST00000535055.1
ENST00000317697.3
ENST00000536549.1
ankyrin repeat and SOCS box containing 8
chrX_-_137793826 12.11 ENST00000315930.6
fibroblast growth factor 13
chr19_+_18942720 12.10 ENST00000262803.5
UPF1 regulator of nonsense transcripts homolog (yeast)
chr18_-_51750948 12.03 ENST00000583046.1
ENST00000398398.2
methyl-CpG binding domain protein 2
chr8_+_85095497 12.00 ENST00000522455.1
ENST00000521695.1
RALY RNA binding protein-like
chr16_-_75498553 11.98 ENST00000569276.1
ENST00000357613.4
ENST00000561878.1
ENST00000566980.1
ENST00000567194.1
transmembrane protein 170A
Uncharacterized protein
chr1_-_223537401 11.97 ENST00000343846.3
ENST00000454695.2
ENST00000484758.2
sushi domain containing 4
chr17_+_12692774 11.86 ENST00000379672.5
ENST00000340825.3
Rho GTPase activating protein 44
chr17_+_73043301 11.81 ENST00000322444.6
potassium channel tetramerization domain containing 2
chr8_-_57359131 11.80 ENST00000518974.1
ENST00000523051.1
ENST00000518770.1
ENST00000451791.2
proenkephalin
chr1_+_228353495 11.79 ENST00000366711.3
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr11_+_46368956 11.71 ENST00000543978.1
diacylglycerol kinase, zeta
chr14_-_91526922 11.71 ENST00000418736.2
ENST00000261991.3
ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr3_-_196065248 11.67 ENST00000446879.1
ENST00000273695.3
transmembrane 4 L six family member 19
chr21_+_47878757 11.66 ENST00000400274.1
ENST00000427143.2
ENST00000318711.7
ENST00000457905.3
ENST00000466639.1
ENST00000435722.3
ENST00000417564.2
DIP2 disco-interacting protein 2 homolog A (Drosophila)
chr3_-_149688655 11.64 ENST00000461930.1
ENST00000423691.2
ENST00000490975.1
ENST00000461868.1
ENST00000452853.2
profilin 2
chr6_-_167040731 11.54 ENST00000265678.4
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr8_-_144241664 11.45 ENST00000342752.4
lymphocyte antigen 6 complex, locus H
chr19_+_42817527 11.43 ENST00000598766.1
transmembrane protein 145
chr10_-_48438974 11.41 ENST00000224605.2
growth differentiation factor 10
chr6_-_39082922 11.39 ENST00000229903.4
SAYSVFN motif domain containing 1
chr1_+_210502238 11.37 ENST00000545154.1
ENST00000537898.1
ENST00000391905.3
ENST00000545781.1
ENST00000261458.3
ENST00000308852.6
hedgehog acyltransferase
chr12_-_121734489 11.36 ENST00000412367.2
ENST00000402834.4
ENST00000404169.3
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr1_-_241520525 11.24 ENST00000366565.1
regulator of G-protein signaling 7
chr10_-_104179682 11.23 ENST00000406432.1
pleckstrin and Sec7 domain containing
chr11_+_113930291 11.22 ENST00000335953.4
zinc finger and BTB domain containing 16
chr7_-_150974494 11.21 ENST00000392811.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr11_+_108535849 11.20 ENST00000526794.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr5_-_146258291 11.14 ENST00000394411.4
ENST00000453001.1
protein phosphatase 2, regulatory subunit B, beta
chr6_-_13487784 11.13 ENST00000379287.3
glucose-fructose oxidoreductase domain containing 1
chr2_+_29338236 11.13 ENST00000320081.5
CAP-GLY domain containing linker protein family, member 4
chr12_+_53773944 11.08 ENST00000551969.1
ENST00000327443.4
Sp1 transcription factor
chr15_+_99645277 11.08 ENST00000336292.6
ENST00000328642.7
synemin, intermediate filament protein
chr19_+_48281928 10.98 ENST00000593892.1
selenoprotein W, 1
chr1_-_15911510 10.97 ENST00000375826.3
agmatine ureohydrolase (agmatinase)
chr2_-_28113965 10.93 ENST00000302188.3
ribokinase
chr15_-_77712477 10.91 ENST00000560626.2
pseudopodium-enriched atypical kinase 1
chrX_-_2418596 10.87 ENST00000381218.3
zinc finger, BED-type containing 1
chr2_+_113033164 10.87 ENST00000409871.1
ENST00000343936.4
zinc finger CCCH-type containing 6
chr11_-_66336060 10.86 ENST00000310325.5
cathepsin F
chr3_+_49449636 10.80 ENST00000273590.3
T-cell leukemia translocation altered
chr6_-_52860171 10.64 ENST00000370963.4
glutathione S-transferase alpha 4
chr8_-_134309335 10.64 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
N-myc downstream regulated 1
chr3_-_179169330 10.63 ENST00000232564.3
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr15_+_29131103 10.60 ENST00000558402.1
ENST00000558330.1
amyloid beta (A4) precursor protein-binding, family A, member 2
chr11_-_132813566 10.59 ENST00000331898.7
opioid binding protein/cell adhesion molecule-like
chr16_-_75498308 10.51 ENST00000569540.1
transmembrane protein 170A
chr7_-_158622210 10.47 ENST00000251527.5
extended synaptotagmin-like protein 2
chr16_+_66914264 10.47 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr8_+_85095553 10.44 ENST00000521268.1
RALY RNA binding protein-like
chr2_+_207308539 10.41 ENST00000374416.1
ENST00000374415.3
ADAM metallopeptidase domain 23
chr16_-_31085514 10.35 ENST00000300849.4
zinc finger protein 668
chr10_-_977564 10.29 ENST00000406525.2
La ribonucleoprotein domain family, member 4B
chr5_+_65892174 10.20 ENST00000404260.3
ENST00000403625.2
ENST00000406374.1
microtubule associated serine/threonine kinase family member 4
chr22_+_29999647 10.17 ENST00000334961.7
ENST00000353887.4
neurofibromin 2 (merlin)
chr19_+_48281946 10.16 ENST00000595615.1
selenoprotein W, 1
chr19_-_460996 10.10 ENST00000264554.6
SHC (Src homology 2 domain containing) transforming protein 2
chr9_-_115095851 10.09 ENST00000343327.2
polypyrimidine tract binding protein 3
chr7_-_108096765 10.00 ENST00000379024.4
ENST00000351718.4
neuronal cell adhesion molecule
chrX_-_153363125 10.00 ENST00000407218.1
ENST00000453960.2
methyl CpG binding protein 2 (Rett syndrome)
chr11_-_64512273 9.99 ENST00000377497.3
ENST00000377487.1
ENST00000430645.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr13_+_113622757 9.96 ENST00000375604.2
MCF.2 cell line derived transforming sequence-like
chr9_-_13279563 9.96 ENST00000541718.1
multiple PDZ domain protein
chr7_-_108096822 9.91 ENST00000379028.3
ENST00000413765.2
ENST00000379022.4
neuronal cell adhesion molecule
chr2_-_97304009 9.89 ENST00000431828.1
ENST00000435669.1
ENST00000440133.1
ENST00000448075.1
KAT8 regulatory NSL complex subunit 3
chr6_-_31864977 9.89 ENST00000395728.3
ENST00000375528.4
euchromatic histone-lysine N-methyltransferase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB14

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
22.4 67.1 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
22.1 66.2 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
17.6 52.8 GO:2000374 cadmium ion homeostasis(GO:0055073) negative regulation of hydrogen peroxide catabolic process(GO:2000296) regulation of oxygen metabolic process(GO:2000374)
13.6 40.9 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
12.8 64.2 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
11.9 35.8 GO:0033693 neurofilament bundle assembly(GO:0033693)
11.4 68.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
10.8 32.4 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
8.5 25.4 GO:0006014 D-ribose metabolic process(GO:0006014)
7.2 35.8 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
6.8 34.0 GO:0030070 insulin processing(GO:0030070)
6.6 26.6 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
6.5 26.0 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
6.2 18.5 GO:0032888 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
5.6 27.9 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
5.4 16.2 GO:0003358 noradrenergic neuron development(GO:0003358)
5.1 15.2 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
5.0 15.1 GO:0044805 late nucleophagy(GO:0044805)
4.9 14.8 GO:0007412 axon target recognition(GO:0007412)
4.9 19.4 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
4.5 13.6 GO:0007518 myoblast fate determination(GO:0007518)
4.4 22.2 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
4.4 17.4 GO:0071492 cellular response to UV-A(GO:0071492)
4.3 8.7 GO:0010165 response to X-ray(GO:0010165)
4.3 55.7 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
4.2 16.9 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
4.2 12.6 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
4.0 20.2 GO:0003219 cardiac right ventricle formation(GO:0003219)
4.0 55.7 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
4.0 11.9 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
3.8 26.9 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
3.8 7.5 GO:1902534 single-organism membrane invagination(GO:1902534)
3.6 14.5 GO:0060385 axonogenesis involved in innervation(GO:0060385)
3.4 10.3 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
3.4 24.0 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
3.4 20.3 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
3.3 9.9 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
3.2 12.9 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
3.2 9.5 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
3.1 145.4 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
3.0 14.8 GO:0097338 response to clozapine(GO:0097338)
2.9 11.8 GO:0051866 general adaptation syndrome(GO:0051866)
2.9 29.4 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
2.8 19.9 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
2.8 11.1 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
2.7 16.5 GO:0060613 fat pad development(GO:0060613)
2.7 11.0 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
2.7 13.6 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
2.7 16.0 GO:0075071 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
2.5 9.9 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
2.4 39.0 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
2.4 12.1 GO:1990834 response to odorant(GO:1990834)
2.4 29.0 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
2.4 18.9 GO:0070544 histone H3-K36 demethylation(GO:0070544)
2.3 7.0 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
2.3 9.2 GO:0060313 negative regulation of blood vessel remodeling(GO:0060313)
2.2 8.9 GO:0022027 interkinetic nuclear migration(GO:0022027)
2.2 15.5 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
2.1 10.7 GO:1990164 histone H2A phosphorylation(GO:1990164)
2.1 12.8 GO:0098535 de novo centriole assembly(GO:0098535)
2.1 8.4 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
2.1 6.2 GO:0051595 response to methylglyoxal(GO:0051595)
2.1 10.3 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
2.1 12.3 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
2.0 2.0 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
2.0 10.2 GO:0060024 rhythmic synaptic transmission(GO:0060024)
2.0 18.1 GO:0035799 ureter maturation(GO:0035799)
2.0 29.9 GO:0015671 oxygen transport(GO:0015671)
2.0 11.9 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
1.9 15.5 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
1.9 15.3 GO:0097106 postsynaptic density organization(GO:0097106) postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
1.9 1.9 GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844) regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
1.9 9.3 GO:0007042 lysosomal lumen acidification(GO:0007042)
1.9 5.6 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
1.8 43.8 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
1.8 59.5 GO:0008045 motor neuron axon guidance(GO:0008045)
1.8 3.6 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
1.8 19.6 GO:0043249 erythrocyte maturation(GO:0043249)
1.8 5.3 GO:0008300 isoprenoid catabolic process(GO:0008300)
1.8 12.3 GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter(GO:0072364)
1.7 22.4 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
1.7 5.1 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
1.7 51.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
1.7 11.9 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
1.7 22.0 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
1.7 11.8 GO:0070166 enamel mineralization(GO:0070166)
1.7 5.0 GO:0014807 regulation of somitogenesis(GO:0014807)
1.7 16.7 GO:0021819 layer formation in cerebral cortex(GO:0021819)
1.6 14.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.6 13.0 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
1.6 16.2 GO:0042373 vitamin K metabolic process(GO:0042373)
1.6 4.8 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
1.6 4.8 GO:1903028 positive regulation of opsonization(GO:1903028)
1.6 3.2 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
1.6 12.7 GO:0007258 JUN phosphorylation(GO:0007258)
1.6 4.7 GO:0003285 septum secundum development(GO:0003285)
1.6 6.2 GO:0045740 positive regulation of DNA replication(GO:0045740) positive regulation of telomerase activity(GO:0051973)
1.6 17.1 GO:0043117 positive regulation of vascular permeability(GO:0043117)
1.6 9.3 GO:0018095 protein polyglutamylation(GO:0018095)
1.5 7.7 GO:0050893 sensory processing(GO:0050893)
1.5 4.6 GO:0016574 histone ubiquitination(GO:0016574)
1.5 89.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
1.5 10.5 GO:0034770 regulation of histone H3-K36 methylation(GO:0000414) histone H4-K20 methylation(GO:0034770)
1.5 14.8 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
1.5 13.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)
1.4 4.3 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
1.4 4.2 GO:0015732 prostaglandin transport(GO:0015732)
1.4 7.0 GO:0008286 insulin receptor signaling pathway(GO:0008286)
1.4 4.2 GO:0006434 seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
1.4 4.2 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
1.4 5.6 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085) regulation of polynucleotide adenylyltransferase activity(GO:1904245)
1.4 4.2 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
1.4 18.0 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
1.4 8.3 GO:0032252 secretory granule localization(GO:0032252)
1.4 2.7 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
1.4 5.4 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
1.3 13.1 GO:0014010 Schwann cell proliferation(GO:0014010)
1.3 8.8 GO:0009597 detection of virus(GO:0009597)
1.2 6.1 GO:2000771 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
1.2 24.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
1.2 3.6 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
1.2 5.8 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
1.1 8.0 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
1.1 11.4 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
1.1 8.0 GO:1903146 regulation of mitophagy(GO:1903146)
1.1 9.1 GO:0030050 vesicle transport along actin filament(GO:0030050)
1.1 5.6 GO:1901909 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
1.1 9.9 GO:0048820 hair follicle maturation(GO:0048820)
1.1 3.3 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
1.1 1.1 GO:0007521 muscle cell fate determination(GO:0007521)
1.0 8.1 GO:0035865 cellular response to potassium ion(GO:0035865)
1.0 4.0 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
1.0 3.0 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
1.0 20.1 GO:0044030 regulation of DNA methylation(GO:0044030)
1.0 15.0 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
1.0 5.9 GO:1904417 regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
1.0 11.6 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
1.0 4.8 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
1.0 23.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
1.0 4.8 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
1.0 21.0 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.9 5.7 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.9 5.7 GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.9 4.7 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.9 2.8 GO:0070781 response to biotin(GO:0070781)
0.9 6.4 GO:0016051 carbohydrate biosynthetic process(GO:0016051)
0.9 26.6 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.9 17.3 GO:0006012 galactose metabolic process(GO:0006012)
0.9 8.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.9 6.3 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.9 3.6 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.9 15.3 GO:0048266 behavioral response to pain(GO:0048266)
0.9 4.4 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.9 5.3 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.9 4.4 GO:0042428 serotonin metabolic process(GO:0042428)
0.9 8.6 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.9 15.5 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.8 22.4 GO:0016578 histone deubiquitination(GO:0016578)
0.8 4.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.8 5.7 GO:0015824 proline transport(GO:0015824)
0.8 7.0 GO:0046929 negative regulation of neurotransmitter secretion(GO:0046929)
0.8 5.4 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.7 3.6 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.7 5.7 GO:0001675 acrosome assembly(GO:0001675)
0.7 11.4 GO:0018345 protein palmitoylation(GO:0018345)
0.7 2.8 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.7 10.3 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.7 5.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.7 0.7 GO:0090241 negative regulation of histone H4 acetylation(GO:0090241)
0.7 4.6 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.7 1.3 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.6 11.0 GO:0030308 negative regulation of cell growth(GO:0030308)
0.6 8.4 GO:0060074 synapse maturation(GO:0060074)
0.6 2.6 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.6 14.6 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.6 2.5 GO:0000103 sulfate assimilation(GO:0000103)
0.6 4.9 GO:0035897 proteolysis in other organism(GO:0035897)
0.6 3.7 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.6 3.0 GO:0086053 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.6 28.3 GO:0001510 RNA methylation(GO:0001510)
0.6 7.1 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.6 39.1 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.6 2.4 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.6 8.7 GO:0045475 locomotor rhythm(GO:0045475)
0.6 2.9 GO:1903059 regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061)
0.6 2.3 GO:0043615 astrocyte cell migration(GO:0043615)
0.6 4.0 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.6 10.8 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.6 13.6 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.6 4.5 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.5 0.5 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.5 9.3 GO:0035418 protein localization to synapse(GO:0035418)
0.5 10.4 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.5 2.7 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.5 4.3 GO:0009886 post-embryonic morphogenesis(GO:0009886)
0.5 11.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.5 6.9 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.5 6.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.5 3.1 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.5 1.5 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.5 3.6 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.5 2.1 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
0.5 4.5 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.5 3.0 GO:0072757 cellular response to camptothecin(GO:0072757) response to camptothecin(GO:1901563)
0.5 5.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.5 10.9 GO:0007628 adult walking behavior(GO:0007628)
0.5 13.8 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.5 4.4 GO:0048813 dendrite morphogenesis(GO:0048813)
0.5 1.9 GO:0019086 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
0.5 15.0 GO:0006400 tRNA modification(GO:0006400)
0.5 3.4 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.5 1.9 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.5 3.8 GO:1904754 positive regulation of vascular associated smooth muscle cell migration(GO:1904754)
0.5 4.3 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.5 6.1 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.5 1.4 GO:0090034 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.5 1.4 GO:0061386 closure of optic fissure(GO:0061386)
0.5 16.7 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.4 4.9 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.4 34.5 GO:0045786 negative regulation of cell cycle(GO:0045786)
0.4 3.1 GO:1990403 embryonic brain development(GO:1990403)
0.4 16.8 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.4 2.6 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.4 3.1 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.4 2.2 GO:0035633 maintenance of blood-brain barrier(GO:0035633) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.4 8.9 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.4 3.8 GO:0050713 positive regulation of MHC class I biosynthetic process(GO:0045345) negative regulation of interleukin-1 beta secretion(GO:0050713)
0.4 6.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.4 1.2 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.4 2.9 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.4 15.2 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.4 14.7 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.4 0.8 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.4 8.7 GO:0042417 dopamine metabolic process(GO:0042417)
0.4 3.5 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.4 14.1 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.4 9.8 GO:0097503 sialylation(GO:0097503)
0.4 1.9 GO:0060353 regulation of cell adhesion molecule production(GO:0060353) positive regulation of cell adhesion molecule production(GO:0060355)
0.4 11.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.4 1.9 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.4 18.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.4 3.4 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.4 11.3 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.4 27.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.4 9.3 GO:0009435 NAD biosynthetic process(GO:0009435)
0.4 7.7 GO:0030183 B cell differentiation(GO:0030183)
0.4 0.7 GO:0061010 common bile duct development(GO:0061009) gall bladder development(GO:0061010)
0.4 13.7 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.4 6.1 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.4 2.5 GO:0035624 receptor transactivation(GO:0035624)
0.3 4.2 GO:0060117 auditory receptor cell development(GO:0060117)
0.3 4.5 GO:0033127 regulation of histone phosphorylation(GO:0033127)
0.3 4.8 GO:0021987 cerebral cortex development(GO:0021987)
0.3 10.6 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.3 2.0 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.3 1.0 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.3 17.1 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.3 10.4 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.3 1.9 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.3 4.8 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.3 5.9 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.3 45.5 GO:0006836 neurotransmitter transport(GO:0006836)
0.3 1.5 GO:1901660 calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
0.3 10.2 GO:1901016 regulation of potassium ion transmembrane transporter activity(GO:1901016)
0.3 7.8 GO:0070207 protein homotrimerization(GO:0070207)
0.3 2.6 GO:0001955 blood vessel maturation(GO:0001955)
0.3 3.4 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.3 1.1 GO:2000398 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.3 1.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.3 1.7 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.3 9.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.3 1.6 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.3 5.9 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.3 9.8 GO:0006198 cAMP catabolic process(GO:0006198)
0.3 3.4 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.3 1.5 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.2 6.0 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.2 3.2 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.2 0.7 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.2 1.6 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.2 29.6 GO:0030449 regulation of complement activation(GO:0030449)
0.2 0.9 GO:0006538 glutamate catabolic process(GO:0006538)
0.2 1.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.2 6.4 GO:0021515 cell differentiation in spinal cord(GO:0021515)
0.2 0.7 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.2 2.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.2 2.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 3.6 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.2 1.4 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.2 0.8 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.2 8.5 GO:0021766 hippocampus development(GO:0021766)
0.2 4.0 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.2 8.0 GO:0033344 cholesterol efflux(GO:0033344)
0.2 13.0 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.2 3.7 GO:0032760 positive regulation of tumor necrosis factor production(GO:0032760)
0.2 1.9 GO:0006325 chromatin organization(GO:0006325)
0.2 4.6 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.2 5.1 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.2 3.0 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.2 3.0 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.2 3.7 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.2 23.6 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.2 2.4 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.2 0.9 GO:0015692 lead ion transport(GO:0015692)
0.2 4.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.2 5.0 GO:0050776 regulation of immune response(GO:0050776)
0.2 0.5 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.2 4.6 GO:0060976 coronary vasculature development(GO:0060976)
0.2 6.6 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.2 0.7 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.2 3.1 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.2 6.4 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.2 0.9 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 20.7 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.2 0.9 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.1 5.8 GO:0046326 positive regulation of glucose import(GO:0046326)
0.1 6.8 GO:0007417 central nervous system development(GO:0007417)
0.1 0.6 GO:0070092 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.1 1.9 GO:0000724 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.1 1.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 1.9 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.6 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 1.5 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.1 0.9 GO:0051961 negative regulation of nervous system development(GO:0051961)
0.1 1.3 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 0.8 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.1 0.6 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 3.0 GO:0015695 organic cation transport(GO:0015695)
0.1 5.9 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 0.7 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1 5.4 GO:0030593 neutrophil chemotaxis(GO:0030593)
0.1 5.3 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.1 2.5 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 3.2 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 0.5 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 8.2 GO:0061045 negative regulation of wound healing(GO:0061045)
0.1 0.3 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378) vitamin D3 metabolic process(GO:0070640)
0.1 10.5 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 5.9 GO:0030031 cell projection assembly(GO:0030031)
0.1 4.1 GO:0051291 protein heterooligomerization(GO:0051291)
0.1 1.5 GO:0015914 phospholipid transport(GO:0015914)
0.1 2.6 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 2.6 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 46.6 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.1 0.4 GO:0090625 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.3 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.1 3.8 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 1.0 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 6.9 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 1.5 GO:0042327 positive regulation of phosphorylation(GO:0042327)
0.1 2.8 GO:0006040 amino sugar metabolic process(GO:0006040)
0.1 0.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 6.2 GO:0042439 ethanolamine-containing compound metabolic process(GO:0042439)
0.1 2.3 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.1 5.0 GO:0007498 mesoderm development(GO:0007498)
0.1 1.6 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 1.0 GO:0051014 actin filament severing(GO:0051014)
0.1 1.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 1.6 GO:0007399 nervous system development(GO:0007399)
0.0 1.1 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 1.3 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 4.4 GO:0070268 cornification(GO:0070268)
0.0 1.4 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 2.3 GO:0001764 neuron migration(GO:0001764)
0.0 3.1 GO:0007286 spermatid development(GO:0007286)
0.0 0.6 GO:0009205 purine nucleoside triphosphate metabolic process(GO:0009144) purine ribonucleoside triphosphate metabolic process(GO:0009205) ATP metabolic process(GO:0046034)
0.0 1.2 GO:0006897 endocytosis(GO:0006897)
0.0 0.8 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.9 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 1.2 GO:0099536 synaptic signaling(GO:0099536)
0.0 0.6 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.2 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.0 0.6 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.8 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.4 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 1.2 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.1 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.2 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
27.9 139.7 GO:0098843 postsynaptic endocytic zone(GO:0098843)
13.2 52.8 GO:0097449 astrocyte projection(GO:0097449)
12.8 64.2 GO:0045298 tubulin complex(GO:0045298)
9.5 38.0 GO:0097454 Schwann cell microvillus(GO:0097454)
8.9 79.9 GO:1990761 growth cone lamellipodium(GO:1990761)
7.5 29.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
6.5 32.4 GO:0044530 supraspliceosomal complex(GO:0044530)
6.2 18.5 GO:0055028 cortical microtubule(GO:0055028) mitotic spindle astral microtubule(GO:0061673)
4.8 33.6 GO:0072487 MSL complex(GO:0072487)
4.3 13.0 GO:0072534 perineuronal net(GO:0072534)
4.0 59.8 GO:0005883 neurofilament(GO:0005883)
3.7 11.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
3.0 12.2 GO:0070695 FHF complex(GO:0070695)
2.6 15.5 GO:0030991 intraciliary transport particle A(GO:0030991)
2.5 20.3 GO:0045179 apical cortex(GO:0045179)
2.5 7.4 GO:0016938 kinesin I complex(GO:0016938)
2.4 7.1 GO:0043291 RAVE complex(GO:0043291)
2.3 27.9 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
2.3 16.2 GO:0070852 cell body fiber(GO:0070852)
2.3 38.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
1.9 28.9 GO:0000124 SAGA complex(GO:0000124)
1.8 5.5 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
1.8 10.9 GO:0002116 semaphorin receptor complex(GO:0002116)
1.7 8.6 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
1.6 146.5 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
1.6 14.2 GO:0005638 lamin filament(GO:0005638)
1.5 19.9 GO:0043194 axon initial segment(GO:0043194)
1.5 7.5 GO:0000125 PCAF complex(GO:0000125)
1.4 5.4 GO:0043293 apoptosome(GO:0043293)
1.3 2.7 GO:1990812 growth cone filopodium(GO:1990812)
1.3 4.0 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
1.3 32.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
1.3 18.3 GO:0008091 spectrin(GO:0008091)
1.3 5.0 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
1.2 8.3 GO:0097427 microtubule bundle(GO:0097427)
1.2 5.8 GO:0005899 insulin receptor complex(GO:0005899)
1.1 10.3 GO:0005955 calcineurin complex(GO:0005955)
1.1 10.3 GO:0072687 meiotic spindle(GO:0072687)
1.1 10.3 GO:0042788 polysomal ribosome(GO:0042788)
1.1 58.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
1.1 21.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
1.0 9.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
1.0 13.0 GO:0043083 synaptic cleft(GO:0043083)
1.0 5.0 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.0 6.9 GO:0000137 Golgi cis cisterna(GO:0000137)
1.0 52.0 GO:0043198 dendritic shaft(GO:0043198)
0.9 3.6 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.9 8.9 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.9 7.1 GO:0044294 dendritic growth cone(GO:0044294)
0.9 34.4 GO:0048786 presynaptic active zone(GO:0048786)
0.8 9.1 GO:0005614 interstitial matrix(GO:0005614)
0.8 9.1 GO:0031045 dense core granule(GO:0031045)
0.8 6.4 GO:0036157 outer dynein arm(GO:0036157)
0.7 28.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.7 8.7 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.7 3.6 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.7 4.3 GO:0035253 ciliary rootlet(GO:0035253)
0.7 14.0 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.7 4.2 GO:0042825 TAP complex(GO:0042825)
0.7 4.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.7 18.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.7 72.1 GO:0005814 centriole(GO:0005814)
0.6 9.6 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.6 3.8 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.6 5.8 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.6 10.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.6 27.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.6 5.0 GO:0005869 dynactin complex(GO:0005869)
0.5 9.8 GO:0071565 nBAF complex(GO:0071565)
0.5 140.3 GO:0060076 excitatory synapse(GO:0060076)
0.5 23.1 GO:0016235 aggresome(GO:0016235)
0.5 10.7 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.5 1.5 GO:0005652 nuclear lamina(GO:0005652)
0.5 22.1 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.5 33.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.5 1.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.5 57.3 GO:0043204 perikaryon(GO:0043204)
0.5 15.3 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.5 17.0 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.4 18.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.4 3.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.4 6.0 GO:0070578 RISC-loading complex(GO:0070578)
0.4 4.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.4 12.4 GO:0005921 gap junction(GO:0005921)
0.4 1.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.4 7.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.4 2.9 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.4 6.4 GO:0031527 filopodium membrane(GO:0031527)
0.3 4.9 GO:0035371 microtubule plus-end(GO:0035371)
0.3 13.1 GO:0042734 presynaptic membrane(GO:0042734)
0.3 47.7 GO:0031225 anchored component of membrane(GO:0031225)
0.3 8.3 GO:0042629 mast cell granule(GO:0042629)
0.3 28.4 GO:0098793 presynapse(GO:0098793)
0.3 16.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.3 2.2 GO:0043218 internode region of axon(GO:0033269) compact myelin(GO:0043218)
0.3 4.2 GO:0097440 apical dendrite(GO:0097440)
0.3 65.8 GO:0005802 trans-Golgi network(GO:0005802)
0.3 25.5 GO:0044306 neuron projection terminus(GO:0044306)
0.3 21.8 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.3 6.5 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.3 1.9 GO:0042555 MCM complex(GO:0042555)
0.3 10.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.3 19.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.3 3.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 12.9 GO:0044456 synapse part(GO:0044456)
0.2 4.2 GO:0000922 spindle pole(GO:0000922)
0.2 1.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.2 2.3 GO:0031143 pseudopodium(GO:0031143)
0.2 3.8 GO:0030133 transport vesicle(GO:0030133)
0.2 3.0 GO:0035102 PRC1 complex(GO:0035102)
0.2 2.3 GO:0000242 pericentriolar material(GO:0000242)
0.2 6.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 4.4 GO:0030057 desmosome(GO:0030057)
0.2 0.9 GO:0070826 paraferritin complex(GO:0070826)
0.2 7.8 GO:0055037 recycling endosome(GO:0055037)
0.2 1.6 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.2 88.0 GO:0000139 Golgi membrane(GO:0000139)
0.1 5.4 GO:0008305 integrin complex(GO:0008305)
0.1 10.9 GO:0043202 lysosomal lumen(GO:0043202)
0.1 6.3 GO:0005844 polysome(GO:0005844)
0.1 9.8 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 1.4 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.1 5.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 14.1 GO:0097060 synaptic membrane(GO:0097060)
0.1 6.8 GO:0030139 endocytic vesicle(GO:0030139)
0.1 5.1 GO:0005902 microvillus(GO:0005902)
0.1 0.6 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.8 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 3.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 6.4 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.1 6.2 GO:0005923 bicellular tight junction(GO:0005923)
0.1 2.7 GO:0032420 stereocilium(GO:0032420)
0.1 33.7 GO:0005813 centrosome(GO:0005813)
0.1 1.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 10.4 GO:0001726 ruffle(GO:0001726)
0.1 2.7 GO:0034707 chloride channel complex(GO:0034707)
0.1 5.7 GO:0016459 myosin complex(GO:0016459)
0.1 0.6 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 4.5 GO:0019898 extrinsic component of membrane(GO:0019898)
0.1 4.2 GO:0030027 lamellipodium(GO:0030027)
0.1 3.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 31.6 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 0.7 GO:0030673 axolemma(GO:0030673)
0.1 3.0 GO:0015030 Cajal body(GO:0015030)
0.0 2.9 GO:0043025 neuronal cell body(GO:0043025)
0.0 4.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.9 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 2.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0035869 ciliary transition zone(GO:0035869)
0.0 5.4 GO:0005929 cilium(GO:0005929)
0.0 2.2 GO:0005815 microtubule organizing center(GO:0005815)
0.0 0.7 GO:0030426 growth cone(GO:0030426)
0.0 0.3 GO:0008180 COP9 signalosome(GO:0008180)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
16.1 64.2 GO:0099609 microtubule lateral binding(GO:0099609)
13.0 38.9 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
11.6 139.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
8.3 66.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
5.9 41.3 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
5.1 15.2 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
4.6 59.8 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
4.3 17.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
4.2 12.6 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
4.1 53.7 GO:0046870 cadmium ion binding(GO:0046870)
4.1 12.3 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
4.0 16.2 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
3.7 14.8 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
3.7 25.6 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
3.6 10.7 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
3.5 10.5 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
3.3 85.1 GO:0031489 myosin V binding(GO:0031489)
3.2 9.7 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
3.1 58.3 GO:0048156 tau protein binding(GO:0048156)
2.7 10.9 GO:0004803 transposase activity(GO:0004803)
2.7 29.6 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
2.7 13.4 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
2.6 15.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
2.6 13.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
2.4 14.4 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
2.4 9.5 GO:0016972 flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
2.4 18.9 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
2.3 9.3 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
2.3 29.9 GO:0005344 oxygen transporter activity(GO:0005344)
2.1 25.2 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
2.1 8.4 GO:0035939 microsatellite binding(GO:0035939)
2.0 6.0 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
2.0 11.9 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
1.9 9.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
1.8 43.9 GO:0043015 gamma-tubulin binding(GO:0043015)
1.8 14.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
1.8 19.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
1.8 28.4 GO:0019992 diacylglycerol binding(GO:0019992)
1.7 7.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
1.7 10.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
1.7 11.8 GO:0001515 opioid peptide activity(GO:0001515)
1.7 6.7 GO:0016361 activin receptor activity, type I(GO:0016361)
1.7 28.3 GO:0003680 AT DNA binding(GO:0003680)
1.6 19.4 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
1.6 4.8 GO:0061663 NEDD8 ligase activity(GO:0061663)
1.6 9.5 GO:0039552 RIG-I binding(GO:0039552)
1.5 20.1 GO:0051011 microtubule minus-end binding(GO:0051011)
1.5 16.9 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
1.5 19.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
1.5 4.5 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
1.5 18.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
1.5 4.4 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
1.5 26.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
1.5 14.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
1.4 4.2 GO:0004828 serine-tRNA ligase activity(GO:0004828)
1.4 4.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
1.3 6.6 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
1.3 32.9 GO:0004383 guanylate cyclase activity(GO:0004383)
1.3 6.5 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
1.3 7.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
1.3 5.1 GO:0008940 nitrate reductase activity(GO:0008940)
1.3 5.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
1.2 9.5 GO:0035374 chondroitin sulfate binding(GO:0035374)
1.2 4.7 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
1.2 18.9 GO:0097109 neuroligin family protein binding(GO:0097109)
1.2 15.2 GO:0031005 filamin binding(GO:0031005)
1.1 6.9 GO:0003696 satellite DNA binding(GO:0003696)
1.1 44.1 GO:0046875 ephrin receptor binding(GO:0046875)
1.1 5.6 GO:0052845 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
1.1 8.5 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
1.0 4.2 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
1.0 45.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
1.0 26.6 GO:0017075 syntaxin-1 binding(GO:0017075)
1.0 3.1 GO:0000995 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) transcription factor activity, core RNA polymerase III binding(GO:0000995) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
1.0 3.0 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
1.0 20.9 GO:0043560 insulin receptor substrate binding(GO:0043560)
1.0 3.0 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.9 5.7 GO:0004882 androgen receptor activity(GO:0004882)
0.9 8.4 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.9 24.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.9 4.6 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.9 5.5 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.9 10.1 GO:0017091 AU-rich element binding(GO:0017091)
0.9 4.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.9 9.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.8 2.5 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.8 2.5 GO:0017002 activin-activated receptor activity(GO:0017002)
0.8 3.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.8 30.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.8 10.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.8 2.4 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.8 11.0 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.8 13.1 GO:0005112 Notch binding(GO:0005112)
0.8 1.5 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.8 4.6 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.8 13.0 GO:0070888 E-box binding(GO:0070888)
0.8 12.0 GO:0004707 MAP kinase activity(GO:0004707)
0.7 8.8 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.7 3.7 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.7 5.8 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.7 5.0 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.7 7.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.7 25.4 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.7 11.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.7 4.9 GO:0050682 AF-2 domain binding(GO:0050682)
0.7 25.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.7 1.3 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.7 2.7 GO:0034046 poly(G) binding(GO:0034046)
0.7 4.0 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.7 10.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.7 4.6 GO:0051525 NFAT protein binding(GO:0051525)
0.7 0.7 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.6 13.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.6 11.7 GO:0070411 I-SMAD binding(GO:0070411)
0.6 4.5 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.6 8.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.6 28.5 GO:0030332 cyclin binding(GO:0030332)
0.6 1.9 GO:0032093 SAM domain binding(GO:0032093)
0.6 34.0 GO:0042169 SH2 domain binding(GO:0042169)
0.6 11.8 GO:0097602 cullin family protein binding(GO:0097602)
0.6 19.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.6 3.0 GO:0086077 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.6 23.9 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.6 40.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.6 9.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.5 13.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.5 7.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.5 32.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.5 27.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.5 13.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.5 3.6 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.5 7.7 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.5 5.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.5 2.0 GO:0043237 laminin-1 binding(GO:0043237)
0.5 1.9 GO:0005534 galactose binding(GO:0005534)
0.5 6.6 GO:0050780 dopamine receptor binding(GO:0050780)
0.5 2.8 GO:0005499 vitamin D binding(GO:0005499)
0.5 1.4 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.5 2.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.5 22.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.5 3.6 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.5 1.4 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.5 6.8 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.4 7.1 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.4 8.7 GO:0045504 dynein heavy chain binding(GO:0045504)
0.4 4.3 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.4 5.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.4 11.4 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.4 8.4 GO:0071837 HMG box domain binding(GO:0071837)
0.4 5.4 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.4 2.9 GO:0043621 protein self-association(GO:0043621)
0.4 3.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.4 10.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.4 65.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.4 15.4 GO:0003785 actin monomer binding(GO:0003785)
0.4 5.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.4 4.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.4 20.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.4 3.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.4 1.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.4 8.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.4 8.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.4 5.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.3 2.8 GO:0008172 S-methyltransferase activity(GO:0008172)
0.3 5.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 3.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.3 9.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.3 31.9 GO:0008013 beta-catenin binding(GO:0008013)
0.3 4.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.3 2.5 GO:0019215 intermediate filament binding(GO:0019215)
0.3 0.9 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.3 11.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.3 9.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.3 1.5 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.3 2.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.3 15.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.3 12.5 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.3 5.4 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.3 2.8 GO:0009374 biotin binding(GO:0009374)
0.3 6.6 GO:0008198 ferrous iron binding(GO:0008198)
0.3 9.8 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.3 1.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.3 6.4 GO:0030507 spectrin binding(GO:0030507)
0.3 1.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 28.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 6.9 GO:0019894 kinesin binding(GO:0019894)
0.2 3.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.2 11.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.2 35.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.2 4.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 0.9 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.2 15.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 1.8 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.2 3.9 GO:0005522 profilin binding(GO:0005522)
0.2 2.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 0.6 GO:0070984 SET domain binding(GO:0070984)
0.2 5.6 GO:0001972 retinoic acid binding(GO:0001972)
0.2 2.0 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.2 10.8 GO:0035064 methylated histone binding(GO:0035064)
0.2 1.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 1.7 GO:0070412 R-SMAD binding(GO:0070412)
0.2 5.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 4.0 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.2 3.8 GO:0032183 SUMO binding(GO:0032183)
0.2 4.8 GO:0043236 laminin binding(GO:0043236)
0.2 5.6 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.2 40.2 GO:0008022 protein C-terminus binding(GO:0008022)
0.2 0.9 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 9.4 GO:0030276 clathrin binding(GO:0030276)
0.2 18.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 8.0 GO:0008009 chemokine activity(GO:0008009)
0.2 0.8 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.2 0.5 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.2 6.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 5.8 GO:0005158 insulin receptor binding(GO:0005158)
0.1 11.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 8.1 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 1.9 GO:0004697 protein kinase C activity(GO:0004697)
0.1 4.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 6.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 4.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 5.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.4 GO:0051787 misfolded protein binding(GO:0051787)
0.1 4.8 GO:0043531 ADP binding(GO:0043531)
0.1 2.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 2.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 7.8 GO:0044325 ion channel binding(GO:0044325)
0.1 7.2 GO:0016247 channel regulator activity(GO:0016247)
0.1 4.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.3 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 4.7 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 2.3 GO:0015929 hexosaminidase activity(GO:0015929)
0.1 0.4 GO:0035198 miRNA binding(GO:0035198)
0.1 5.8 GO:0005262 calcium channel activity(GO:0005262)
0.1 3.5 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.1 8.2 GO:0005057 receptor signaling protein activity(GO:0005057)
0.1 3.0 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 1.6 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.7 GO:0045499 ErbB-3 class receptor binding(GO:0043125) chemorepellent activity(GO:0045499)
0.1 0.5 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.5 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.1 4.7 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 13.9 GO:0005516 calmodulin binding(GO:0005516)
0.1 2.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 3.1 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 2.7 GO:0015485 cholesterol binding(GO:0015485)
0.1 1.9 GO:0043130 ubiquitin binding(GO:0043130)
0.1 10.6 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 2.0 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 3.5 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 0.6 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 1.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.5 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 13.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 14.0 GO:0008270 zinc ion binding(GO:0008270)
0.0 1.1 GO:0051287 NAD binding(GO:0051287)
0.0 1.9 GO:0005506 iron ion binding(GO:0005506)
0.0 0.6 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.4 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 49.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
1.8 101.4 PID NCADHERIN PATHWAY N-cadherin signaling events
1.7 41.9 PID LPA4 PATHWAY LPA4-mediated signaling events
1.7 85.5 PID RAS PATHWAY Regulation of Ras family activation
1.6 26.2 PID S1P S1P4 PATHWAY S1P4 pathway
1.6 4.8 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
1.4 5.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.9 56.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.8 39.8 PID RHOA PATHWAY RhoA signaling pathway
0.7 44.0 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.7 26.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.7 16.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.6 18.4 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.6 2.5 PID ALK1 PATHWAY ALK1 signaling events
0.6 34.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.6 57.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.5 11.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.5 16.5 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.5 24.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.5 14.9 PID IL3 PATHWAY IL3-mediated signaling events
0.4 11.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.4 19.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.4 11.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.4 5.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.4 11.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.4 2.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3 9.7 PID IL1 PATHWAY IL1-mediated signaling events
0.3 5.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.3 16.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.3 11.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 1.5 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2 5.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 58.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 8.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.2 9.2 PID LKB1 PATHWAY LKB1 signaling events
0.2 9.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.2 3.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.2 15.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.2 3.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.2 2.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.2 0.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 2.2 PID INSULIN PATHWAY Insulin Pathway
0.1 5.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 6.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 1.9 ST GA13 PATHWAY G alpha 13 Pathway
0.1 47.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 1.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 12.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 5.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 4.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 3.2 PID ATR PATHWAY ATR signaling pathway
0.1 2.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.0 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 3.0 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 1.7 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 1.7 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 5.3 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.1 1.5 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.8 PID SHP2 PATHWAY SHP2 signaling
0.0 1.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 2.0 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
7.5 180.0 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
2.7 32.9 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
2.3 77.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
2.3 29.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
1.9 29.7 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
1.8 3.6 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
1.7 10.3 REACTOME SIGNALING BY GPCR Genes involved in Signaling by GPCR
1.7 55.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.5 4.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
1.3 48.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
1.2 55.8 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
1.2 19.0 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
1.2 30.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
1.1 22.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
1.1 13.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
1.0 26.1 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.9 15.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.9 6.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.8 14.0 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.8 23.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.7 15.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.7 9.7 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.7 12.3 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.7 14.8 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.6 14.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.6 17.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.6 18.3 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.5 8.7 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.5 4.2 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.5 14.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.5 23.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.5 9.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.5 1.5 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.5 7.9 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.4 8.5 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.4 11.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.4 13.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.4 7.7 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.4 8.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.4 7.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.4 9.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.4 3.6 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.4 16.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.4 5.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.4 4.8 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.4 12.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.3 12.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.3 9.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.3 56.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.3 7.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.3 12.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.3 4.0 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.3 5.5 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.2 3.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 5.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 5.7 REACTOME KINESINS Genes involved in Kinesins
0.2 3.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 7.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 5.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 4.2 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.2 5.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 4.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 4.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.2 4.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.2 10.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 5.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 33.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.2 1.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.2 3.0 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 2.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 2.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 5.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 3.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 5.5 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 1.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 3.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 5.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 5.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.0 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 5.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.5 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.1 1.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 2.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 3.0 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 1.9 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.1 0.7 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 1.6 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 5.2 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 6.3 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.1 0.9 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 5.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 11.3 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.1 5.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 0.8 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.1 1.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.7 REACTOME PI3K EVENTS IN ERBB4 SIGNALING Genes involved in PI3K events in ERBB4 signaling
0.0 0.1 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 1.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.8 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation