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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ZBTB33_CHD2

Z-value: 4.62

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Transcription factors associated with ZBTB33_CHD2

Gene Symbol Gene ID Gene Info
ENSG00000177485.6 zinc finger and BTB domain containing 33
ENSG00000173575.14 chromodomain helicase DNA binding protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CHD2hg19_v2_chr15_+_93443419_93443580-0.821.4e-53Click!
ZBTB33hg19_v2_chrX_+_119384607_119384720-0.711.1e-34Click!

Activity profile of ZBTB33_CHD2 motif

Sorted Z-values of ZBTB33_CHD2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_111992064 217.28 ENST00000483994.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
chr4_-_103749179 184.22 ENST00000502690.1
ubiquitin-conjugating enzyme E2D 3
chr20_-_34330129 164.85 ENST00000397370.3
ENST00000528062.3
ENST00000407261.4
ENST00000374038.3
ENST00000361162.6
RNA binding motif protein 39
chr4_-_103749205 146.37 ENST00000508249.1
ubiquitin-conjugating enzyme E2D 3
chr12_+_123237321 129.21 ENST00000280557.6
ENST00000455982.2
density-regulated protein
chr1_+_111991474 120.90 ENST00000369722.3
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
chr12_-_27090896 116.15 ENST00000539625.1
ENST00000538727.1
asunder spermatogenesis regulator
chr12_-_29534074 115.73 ENST00000546839.1
ENST00000360150.4
ENST00000552155.1
ENST00000550353.1
ENST00000548441.1
ENST00000552132.1
ERGIC and golgi 2
chr12_-_27091183 113.59 ENST00000544548.1
ENST00000261191.7
ENST00000537336.1
asunder spermatogenesis regulator
chr1_-_78148324 110.80 ENST00000370801.3
ENST00000433749.1
zinc finger, ZZ-type containing 3
chr1_+_43824669 107.78 ENST00000372462.1
cell division cycle 20
chr17_-_4843206 107.62 ENST00000576951.1
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chr1_+_43824577 105.44 ENST00000310955.6
cell division cycle 20
chr7_-_2272566 100.40 ENST00000402746.1
ENST00000265854.7
ENST00000429779.1
ENST00000399654.2
MAD1 mitotic arrest deficient-like 1 (yeast)
chr4_-_103749313 90.21 ENST00000394803.5
ubiquitin-conjugating enzyme E2D 3
chr10_-_112064665 88.05 ENST00000369603.5
survival motor neuron domain containing 1
chr1_-_24306835 87.98 ENST00000484146.2
serine/arginine-rich splicing factor 10
chr6_+_47445467 87.44 ENST00000359314.5
CD2-associated protein
chr17_-_53046058 86.48 ENST00000571584.1
ENST00000299335.3
cytochrome c oxidase assembly homolog 11 (yeast)
chr21_-_30445886 85.93 ENST00000431234.1
ENST00000540844.1
ENST00000286788.4
chaperonin containing TCP1, subunit 8 (theta)
chr5_+_170814803 85.82 ENST00000521672.1
ENST00000351986.6
ENST00000393820.2
ENST00000523622.1
nucleophosmin (nucleolar phosphoprotein B23, numatrin)
chr9_-_123605177 83.22 ENST00000373904.5
ENST00000210313.3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
chr12_-_102513843 79.12 ENST00000551744.2
ENST00000552283.1
nucleoporin 37kDa
chrX_+_23685653 77.47 ENST00000379331.3
peroxiredoxin 4
chr4_-_103749105 76.78 ENST00000394801.4
ENST00000394804.2
ubiquitin-conjugating enzyme E2D 3
chr15_-_76603727 76.37 ENST00000560595.1
ENST00000433983.2
ENST00000559386.1
ENST00000559602.1
ENST00000560726.1
ENST00000557943.1
electron-transfer-flavoprotein, alpha polypeptide
chr17_+_34900737 74.54 ENST00000304718.4
ENST00000485685.2
gametogenetin binding protein 2
chr6_+_35995488 73.62 ENST00000229795.3
mitogen-activated protein kinase 14
chr4_-_103748880 73.36 ENST00000453744.2
ENST00000349311.8
ubiquitin-conjugating enzyme E2D 3
chr15_+_66797627 72.74 ENST00000565627.1
ENST00000564179.1
zwilch kinetochore protein
chr6_-_100016678 72.43 ENST00000523799.1
ENST00000520429.1
cyclin C
chr6_+_35995531 72.34 ENST00000229794.4
mitogen-activated protein kinase 14
chr5_+_169010638 71.62 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
spindle apparatus coiled-coil protein 1
chr6_+_35436167 70.92 ENST00000322203.6
ribosomal protein L10a
chr15_+_66797455 70.88 ENST00000446801.2
zwilch kinetochore protein
chr3_+_160117087 70.13 ENST00000357388.3
structural maintenance of chromosomes 4
chr2_+_3622893 69.74 ENST00000407445.3
ENST00000403564.1
ribosomal protein S7
chr10_+_51565108 69.50 ENST00000438493.1
ENST00000452682.1
nuclear receptor coactivator 4
chr10_+_51565188 68.69 ENST00000430396.2
ENST00000374087.4
ENST00000414907.2
nuclear receptor coactivator 4
chr1_-_165738072 68.02 ENST00000481278.1
transmembrane and coiled-coil domains 1
chr3_+_160117418 67.97 ENST00000465903.1
ENST00000485645.1
ENST00000360111.2
ENST00000472991.1
ENST00000467468.1
ENST00000469762.1
ENST00000489573.1
ENST00000462787.1
ENST00000490207.1
ENST00000485867.1
structural maintenance of chromosomes 4
chr4_-_103748696 67.52 ENST00000321805.7
ubiquitin-conjugating enzyme E2D 3
chr2_+_3622795 66.71 ENST00000304921.5
ribosomal protein S7
chr1_-_111991850 66.06 ENST00000411751.2
WD repeat domain 77
chr16_-_2014804 65.38 ENST00000526522.1
ENST00000527302.1
ENST00000529806.1
ENST00000563194.1
ENST00000343262.4
ribosomal protein S2
chr2_+_10262442 64.61 ENST00000360566.2
ribonucleotide reductase M2
chr9_-_125667494 64.57 ENST00000335387.5
ENST00000357244.2
ENST00000373665.2
ring finger and CCCH-type domains 2
chr5_+_138629337 64.55 ENST00000394805.3
ENST00000512876.1
ENST00000513678.1
matrin 3
chr12_+_118454500 64.06 ENST00000537315.1
ENST00000229043.3
ENST00000484086.2
ENST00000420967.1
ENST00000454402.2
ENST00000392542.2
ENST00000535092.1
replication factor C (activator 1) 5, 36.5kDa
chr4_+_17812525 64.06 ENST00000251496.2
non-SMC condensin I complex, subunit G
chr20_-_49547731 63.90 ENST00000396029.3
activity-dependent neuroprotector homeobox
chr6_-_100016492 63.55 ENST00000369217.4
ENST00000369220.4
ENST00000482541.2
cyclin C
chr7_-_158497431 63.30 ENST00000449727.2
ENST00000409339.3
ENST00000409423.1
ENST00000356309.3
non-SMC condensin II complex, subunit G2
chrX_-_118986911 63.07 ENST00000276201.2
ENST00000345865.2
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr5_+_138629389 62.92 ENST00000504045.1
ENST00000504311.1
ENST00000502499.1
matrin 3
chr17_+_73257945 62.53 ENST00000579002.1
mitochondrial ribosomal protein S7
chr1_-_45987526 62.29 ENST00000372079.1
ENST00000262746.1
ENST00000447184.1
ENST00000319248.8
peroxiredoxin 1
chr17_+_65713925 62.08 ENST00000253247.4
nucleolar protein 11
chr2_+_10262857 62.00 ENST00000304567.5
ribonucleotide reductase M2
chr5_+_138629417 61.76 ENST00000510056.1
ENST00000511249.1
ENST00000503811.1
ENST00000511378.1
matrin 3
chr17_+_73257742 59.94 ENST00000579761.1
ENST00000245539.6
mitochondrial ribosomal protein S7
chr2_+_201676256 59.82 ENST00000452206.1
ENST00000410110.2
ENST00000409600.1
basic leucine zipper and W2 domains 1
chr19_+_42364460 59.68 ENST00000593863.1
ribosomal protein S19
chr6_-_100016527 58.41 ENST00000523985.1
ENST00000518714.1
ENST00000520371.1
cyclin C
chr17_-_17184605 57.59 ENST00000268717.5
COP9 signalosome subunit 3
chrX_+_41192595 56.98 ENST00000399959.2
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr1_-_167906277 56.97 ENST00000271373.4
mitochondrial pyruvate carrier 2
chr2_-_70520832 56.89 ENST00000454893.1
ENST00000272348.2
small nuclear ribonucleoprotein polypeptide G
chr5_+_112196919 56.39 ENST00000505459.1
ENST00000282999.3
ENST00000515463.1
signal recognition particle 19kDa
chr7_+_141438393 56.38 ENST00000484178.1
ENST00000473783.1
ENST00000481508.1
single-stranded DNA binding protein 1, mitochondrial
chr2_-_70520539 56.14 ENST00000482975.2
ENST00000438261.1
small nuclear ribonucleoprotein polypeptide G
chr2_+_3622932 55.53 ENST00000406376.1
ribosomal protein S7
chr3_-_145878954 55.49 ENST00000282903.5
ENST00000360060.3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr8_+_42249346 54.84 ENST00000392935.3
ENST00000520115.1
ENST00000522069.1
ENST00000522572.1
voltage-dependent anion channel 3
chr8_+_42249418 54.33 ENST00000521158.1
ENST00000022615.4
voltage-dependent anion channel 3
chr2_+_201676908 53.96 ENST00000409226.1
ENST00000452790.2
basic leucine zipper and W2 domains 1
chr9_+_91926103 53.40 ENST00000314355.6
CDC28 protein kinase regulatory subunit 2
chrX_+_77154935 52.86 ENST00000481445.1
cytochrome c oxidase subunit VIIb
chr2_+_171785824 51.80 ENST00000452526.2
golgi reassembly stacking protein 2, 55kDa
chr3_+_14219858 51.76 ENST00000306024.3
LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr5_-_89705537 50.16 ENST00000522864.1
ENST00000522083.1
ENST00000522565.1
ENST00000522842.1
ENST00000283122.3
centrin, EF-hand protein, 3
chr20_-_49547910 49.73 ENST00000396032.3
activity-dependent neuroprotector homeobox
chr1_-_6295975 49.71 ENST00000343813.5
ENST00000362035.3
isoprenylcysteine carboxyl methyltransferase
chr2_+_201754050 49.64 ENST00000426253.1
ENST00000416651.1
ENST00000454952.1
ENST00000409020.1
ENST00000359683.4
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr1_-_167906020 49.51 ENST00000458574.1
mitochondrial pyruvate carrier 2
chr9_-_130213652 48.71 ENST00000536368.1
ENST00000361436.5
ribosomal protein L12
chrX_-_16888448 48.40 ENST00000468092.1
ENST00000404022.1
ENST00000380087.2
retinoblastoma binding protein 7
chr1_+_110881945 48.06 ENST00000602849.1
ENST00000487146.2
RNA binding motif protein 15
chr13_-_22178284 47.98 ENST00000468222.2
ENST00000382374.4
mitochondrial calcium uptake 2
chr18_-_47018869 47.92 ENST00000583036.1
ENST00000580261.1
ribosomal protein L17
chr9_+_36572851 47.92 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
maternal embryonic leucine zipper kinase
chr16_-_18801582 47.41 ENST00000565420.1
ribosomal protein S15a
chrX_+_23685563 47.30 ENST00000379341.4
peroxiredoxin 4
chr1_-_78444776 47.12 ENST00000370767.1
ENST00000421641.1
far upstream element (FUSE) binding protein 1
chr7_+_117824210 46.79 ENST00000422760.1
ENST00000411938.1
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr5_-_137878887 46.78 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
eukaryotic translation termination factor 1
chr2_-_10587897 46.68 ENST00000405333.1
ENST00000443218.1
ornithine decarboxylase 1
chr6_-_7313381 46.62 ENST00000489567.1
ENST00000479365.1
ENST00000462112.1
ENST00000397511.2
ENST00000534851.1
ENST00000474597.1
ENST00000244763.4
signal sequence receptor, alpha
chr22_+_31795509 46.28 ENST00000331457.4
developmentally regulated GTP binding protein 1
chr2_+_201754135 46.22 ENST00000409357.1
ENST00000409129.2
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr18_-_47018897 45.92 ENST00000418495.1
ribosomal protein L17
chr9_+_136215087 45.58 ENST00000426651.1
ribosomal protein L7a
chr3_-_195270162 45.55 ENST00000438848.1
ENST00000328432.3
protein phosphatase 1, regulatory (inhibitor) subunit 2
chr16_-_18801643 45.10 ENST00000322989.4
ENST00000563390.1
ribosomal protein S15a
chrX_+_48380205 44.42 ENST00000446158.1
ENST00000414061.1
emopamil binding protein (sterol isomerase)
chr10_-_5855350 44.30 ENST00000456041.1
ENST00000380181.3
ENST00000418688.1
ENST00000380132.4
ENST00000609712.1
ENST00000380191.4
GDP dissociation inhibitor 2
chr1_-_6614565 44.28 ENST00000377705.5
nucleolar protein 9
chr15_-_66797172 43.46 ENST00000569438.1
ENST00000569696.1
ENST00000307961.6
ribosomal protein L4
chr8_+_104311059 43.36 ENST00000358755.4
ENST00000523739.1
ENST00000540287.1
frizzled family receptor 6
chr18_-_47018769 43.30 ENST00000583637.1
ENST00000578528.1
ENST00000578532.1
ENST00000580387.1
ENST00000579248.1
ENST00000581373.1
ribosomal protein L17
chr3_-_195808980 42.85 ENST00000360110.4
transferrin receptor
chr5_-_140700322 42.66 ENST00000313368.5
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
chr17_-_4843316 42.49 ENST00000544061.2
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chr7_+_100303676 42.28 ENST00000303151.4
processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
chr4_-_2965052 42.09 ENST00000398071.4
ENST00000502735.1
ENST00000314262.6
ENST00000416614.2
NOP14 nucleolar protein
chr15_-_66649010 41.95 ENST00000367709.4
ENST00000261881.4
TIMELESS interacting protein
chr5_+_10250328 41.92 ENST00000515390.1
chaperonin containing TCP1, subunit 5 (epsilon)
chr17_-_78120936 41.73 ENST00000576547.1
ENST00000269349.3
eukaryotic translation initiation factor 4A3
chr6_-_13814663 41.02 ENST00000359495.2
ENST00000379170.4
mitochondrial calcium uniporter regulator 1
chr17_-_61920280 40.85 ENST00000448276.2
ENST00000577990.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr1_-_11159887 40.39 ENST00000544779.1
ENST00000304457.7
ENST00000376936.4
exosome component 10
chr10_+_70091847 40.03 ENST00000441000.2
ENST00000354695.5
heterogeneous nuclear ribonucleoprotein H3 (2H9)
chr9_-_86595105 39.73 ENST00000457156.1
ENST00000360384.5
ENST00000376263.3
heterogeneous nuclear ribonucleoprotein K
chr14_-_69864993 39.58 ENST00000555373.1
enhancer of rudimentary homolog (Drosophila)
chr5_+_138940742 38.99 ENST00000398733.3
ENST00000253815.2
ENST00000505007.1
ubiquitin-conjugating enzyme E2D 2
chr14_+_20923350 38.44 ENST00000555414.1
ENST00000216714.3
ENST00000553681.1
ENST00000557344.1
ENST00000398030.4
ENST00000557181.1
ENST00000555839.1
ENST00000553368.1
ENST00000556054.1
ENST00000557054.1
ENST00000557592.1
ENST00000557150.1
APEX nuclease (multifunctional DNA repair enzyme) 1
chr5_+_132387633 38.42 ENST00000304858.2
heat shock 70kDa protein 4
chr2_+_207630081 38.17 ENST00000236980.6
ENST00000418289.1
ENST00000402774.3
ENST00000403094.3
FAST kinase domains 2
chr7_+_117824086 38.15 ENST00000249299.2
ENST00000424702.1
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr8_+_33342268 38.15 ENST00000360128.6
MAK16 homolog (S. cerevisiae)
chr14_+_100705322 37.64 ENST00000262238.4
YY1 transcription factor
chr6_+_35995552 37.62 ENST00000468133.1
mitogen-activated protein kinase 14
chr12_-_49351303 37.61 ENST00000256682.4
ADP-ribosylation factor 3
chr10_-_135187193 37.10 ENST00000368547.3
enoyl CoA hydratase, short chain, 1, mitochondrial
chrX_-_107334750 37.08 ENST00000340200.5
ENST00000372296.1
ENST00000372295.1
ENST00000361815.5
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr2_+_160568978 36.71 ENST00000409175.1
ENST00000539065.1
ENST00000259050.4
ENST00000421037.1
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
chr1_-_111991908 36.67 ENST00000235090.5
WD repeat domain 77
chr9_+_86595626 36.57 ENST00000445877.1
ENST00000325875.3
RecQ mediated genome instability 1
chr2_+_74154032 36.44 ENST00000356837.6
deoxyguanosine kinase
chr3_+_171758344 36.29 ENST00000336824.4
ENST00000423424.1
fibronectin type III domain containing 3B
chr2_+_74153953 36.20 ENST00000264093.4
ENST00000348222.1
deoxyguanosine kinase
chr1_+_174969262 36.09 ENST00000406752.1
ENST00000405362.1
calcyclin binding protein
chr3_+_169684553 35.85 ENST00000337002.4
ENST00000480708.1
SEC62 homolog (S. cerevisiae)
chr16_-_57481278 35.81 ENST00000567751.1
ENST00000568940.1
ENST00000563341.1
ENST00000565961.1
ENST00000569370.1
ENST00000567518.1
ENST00000565786.1
ENST00000394391.4
cytokine induced apoptosis inhibitor 1
chr2_-_136743169 35.67 ENST00000264161.4
aspartyl-tRNA synthetase
chr8_+_104310661 35.51 ENST00000522566.1
frizzled family receptor 6
chr20_+_61569463 35.40 ENST00000266069.3
GID complex subunit 8
chr15_+_59397275 34.91 ENST00000288207.2
cyclin B2
chrX_-_152989798 34.80 ENST00000441714.1
ENST00000442093.1
ENST00000429550.1
ENST00000345046.6
B-cell receptor-associated protein 31
chr13_+_21750780 34.62 ENST00000309594.4
mitochondrial ribosomal protein 63
chr19_+_42364313 34.59 ENST00000601492.1
ENST00000600467.1
ENST00000221975.2
ribosomal protein S19
chr17_+_65714018 34.55 ENST00000581106.1
ENST00000535137.1
nucleolar protein 11
chrX_-_107334790 34.38 ENST00000217958.3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr5_+_65440032 34.26 ENST00000334121.6
splicing regulatory glutamine/lysine-rich protein 1
chr1_-_24306768 34.14 ENST00000374453.3
ENST00000453840.3
serine/arginine-rich splicing factor 10
chrX_+_40944871 33.29 ENST00000378308.2
ENST00000324545.8
ubiquitin specific peptidase 9, X-linked
chr9_-_86595503 32.97 ENST00000376281.4
ENST00000376264.2
heterogeneous nuclear ribonucleoprotein K
chr1_-_36107445 32.97 ENST00000373237.3
proteasome (prosome, macropain) subunit, beta type, 2
chr11_-_46142948 32.81 ENST00000257821.4
PHD finger protein 21A
chr4_-_120988229 32.66 ENST00000296509.6
MAD2 mitotic arrest deficient-like 1 (yeast)
chr19_+_34663397 32.58 ENST00000540746.2
ENST00000544216.3
ENST00000433627.5
LSM14A, SCD6 homolog A (S. cerevisiae)
chr4_-_1713977 32.06 ENST00000318386.4
stem-loop binding protein
chr19_-_8386238 31.62 ENST00000301457.2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
chr8_-_80942061 31.44 ENST00000519386.1
mitochondrial ribosomal protein S28
chr2_+_120517174 31.04 ENST00000263708.2
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr8_+_145149930 30.72 ENST00000318911.4
cytochrome c-1
chr2_-_74405929 30.65 ENST00000396049.4
MOB kinase activator 1A
chr20_-_32891151 30.36 ENST00000217426.2
adenosylhomocysteinase
chr13_+_34392185 30.27 ENST00000380071.3
replication factor C (activator 1) 3, 38kDa
chr1_-_159894319 30.20 ENST00000320307.4
transgelin 2
chr3_+_23847432 29.72 ENST00000346855.3
ubiquitin-conjugating enzyme E2E 1
chr9_-_19380196 29.64 ENST00000315377.4
ENST00000380384.1
ENST00000380381.3
ENST00000380394.4
ribosomal protein S6
chr19_+_16187085 29.58 ENST00000300933.4
tropomyosin 4
chr15_+_59397298 29.45 ENST00000559622.1
cyclin B2
chr1_+_87170577 29.43 ENST00000482504.1
SH3-domain GRB2-like endophilin B1
chr2_+_39005336 29.43 ENST00000409566.1
gem (nuclear organelle) associated protein 6
chr11_+_64808675 29.32 ENST00000529996.1
SAC3 domain containing 1
chr10_-_126847276 29.09 ENST00000531469.1
C-terminal binding protein 2
chrX_-_152989531 29.08 ENST00000458587.2
ENST00000416815.1
B-cell receptor-associated protein 31
chr20_+_35202909 28.69 ENST00000558530.1
ENST00000558028.1
ENST00000560025.1
TGIF2-C20orf24 readthrough
TGFB-induced factor homeobox 2
chr2_+_39005325 28.69 ENST00000281950.3
gem (nuclear organelle) associated protein 6
chr1_+_167906056 28.67 ENST00000367840.3
DDB1 and CUL4 associated factor 6
chr9_+_136215044 28.66 ENST00000323345.6
ribosomal protein L7a
chr11_+_64808368 28.21 ENST00000531072.1
ENST00000398846.1
SAC3 domain containing 1
chr12_-_49351228 27.87 ENST00000541959.1
ENST00000447318.2
ADP-ribosylation factor 3
chrX_+_12809463 27.64 ENST00000380663.3
ENST00000380668.5
ENST00000398491.2
ENST00000489404.1
phosphoribosyl pyrophosphate synthetase 2
chr2_+_27851863 27.50 ENST00000264718.3
ENST00000610189.1
GPN-loop GTPase 1
chr3_+_23847394 27.48 ENST00000306627.3
ubiquitin-conjugating enzyme E2E 1
chr7_+_141438118 27.23 ENST00000265304.6
ENST00000498107.1
ENST00000467681.1
ENST00000465582.1
ENST00000463093.1
single-stranded DNA binding protein 1, mitochondrial
chr5_+_162864575 27.18 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
cyclin G1
chr5_+_70883117 26.83 ENST00000340941.6
methylcrotonoyl-CoA carboxylase 2 (beta)
chr4_+_26322185 26.78 ENST00000361572.6
recombination signal binding protein for immunoglobulin kappa J region
chr4_-_74124502 26.77 ENST00000358602.4
ENST00000330838.6
ENST00000561029.1
ankyrin repeat domain 17
chr8_+_37963311 26.59 ENST00000428278.2
ENST00000521652.1
ash2 (absent, small, or homeotic)-like (Drosophila)
chr1_+_100316041 26.54 ENST00000370165.3
ENST00000370163.3
ENST00000294724.4
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr19_-_14530143 26.41 ENST00000242776.4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr5_+_115177178 26.12 ENST00000316788.7
adaptor-related protein complex 3, sigma 1 subunit
chr2_+_170655789 26.07 ENST00000409333.1
Sjogren syndrome antigen B (autoantigen La)
chr8_-_80942139 25.96 ENST00000521434.1
ENST00000519120.1
ENST00000520946.1
mitochondrial ribosomal protein S28
chr17_-_37607497 25.71 ENST00000394287.3
ENST00000300651.6
mediator complex subunit 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB33_CHD2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
43.1 129.2 GO:0002188 translation reinitiation(GO:0002188)
36.7 183.6 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
30.9 154.7 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
29.1 87.4 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
28.7 86.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
28.0 112.1 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
26.6 106.5 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
26.3 78.9 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
25.0 150.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
25.0 124.8 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
24.8 74.5 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
24.2 72.6 GO:1901189 arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
23.9 191.3 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
21.6 86.5 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
19.4 58.3 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
18.9 94.3 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
18.8 56.4 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
18.5 55.5 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
18.2 72.7 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
18.2 72.6 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
17.3 138.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
17.1 102.7 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
16.9 169.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
16.2 113.6 GO:0033484 nitric oxide homeostasis(GO:0033484)
16.0 48.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
15.9 95.6 GO:0015853 adenine transport(GO:0015853)
15.9 47.6 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
15.8 63.3 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
15.0 75.0 GO:0042256 mature ribosome assembly(GO:0042256)
15.0 689.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
14.8 89.0 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
14.2 455.0 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
14.0 42.1 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
13.9 41.7 GO:0045900 negative regulation of translational elongation(GO:0045900)
13.7 68.7 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
13.5 40.4 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
13.3 213.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
13.0 13.0 GO:0061317 canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
12.8 38.4 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
12.8 63.9 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
12.1 48.4 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
11.7 46.7 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
11.6 11.6 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
11.3 33.9 GO:0032203 telomere formation via telomerase(GO:0032203)
10.7 85.8 GO:0060699 regulation of endoribonuclease activity(GO:0060699)
10.7 32.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
10.7 64.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
10.2 50.8 GO:0042780 tRNA 3'-end processing(GO:0042780)
9.8 127.9 GO:1990173 protein localization to nuclear body(GO:1903405) positive regulation of establishment of protein localization to telomere(GO:1904851) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
9.7 58.4 GO:0090235 regulation of metaphase plate congression(GO:0090235)
9.2 27.5 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
9.1 145.7 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
9.0 98.9 GO:0006983 ER overload response(GO:0006983)
8.9 44.4 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
8.8 237.4 GO:0000470 maturation of LSU-rRNA(GO:0000470)
8.6 25.7 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
8.5 110.6 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
8.4 83.6 GO:0051096 positive regulation of helicase activity(GO:0051096)
8.1 8.1 GO:0061738 late endosomal microautophagy(GO:0061738) negative regulation of exosomal secretion(GO:1903542)
8.0 23.9 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
7.9 23.8 GO:0014016 neuroblast differentiation(GO:0014016)
7.7 23.2 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
7.7 46.2 GO:1904044 response to aldosterone(GO:1904044)
7.6 38.2 GO:0061668 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
7.6 22.9 GO:1902568 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
7.6 30.4 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
7.1 57.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
7.1 7.1 GO:0070203 regulation of establishment of protein localization to telomere(GO:0070203)
7.0 63.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
6.8 20.4 GO:0002276 basophil activation involved in immune response(GO:0002276)
6.7 26.8 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
6.6 19.9 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
6.5 19.5 GO:0007113 endomitotic cell cycle(GO:0007113)
6.4 32.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
6.1 24.4 GO:0002572 pro-T cell differentiation(GO:0002572)
5.5 171.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
5.5 27.6 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
5.5 126.6 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
5.5 114.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
5.4 37.9 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
5.3 42.7 GO:0015846 polyamine transport(GO:0015846)
5.3 52.8 GO:0010265 SCF complex assembly(GO:0010265)
5.2 15.5 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
5.1 76.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
4.9 14.6 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
4.9 63.2 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
4.6 27.4 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
4.5 54.3 GO:0034501 protein localization to kinetochore(GO:0034501)
4.4 39.9 GO:0006552 leucine catabolic process(GO:0006552)
4.2 20.9 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
4.1 536.3 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
4.1 12.3 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
4.1 16.2 GO:0072423 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
4.0 12.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
4.0 12.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
3.9 23.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
3.8 138.2 GO:0006622 protein targeting to lysosome(GO:0006622)
3.8 26.6 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
3.8 11.4 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
3.6 18.1 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
3.6 57.6 GO:0000338 protein deneddylation(GO:0000338)
3.5 41.9 GO:0000076 DNA replication checkpoint(GO:0000076)
3.5 38.4 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
3.4 17.2 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
3.4 60.5 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
3.3 9.9 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
3.3 9.8 GO:0051684 maintenance of Golgi location(GO:0051684)
3.2 12.8 GO:0031291 Ran protein signal transduction(GO:0031291)
3.2 19.1 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
3.2 9.5 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
3.1 9.3 GO:0048250 mitochondrial iron ion transport(GO:0048250)
3.0 60.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
3.0 29.8 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
3.0 17.8 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
2.9 11.7 GO:0006382 adenosine to inosine editing(GO:0006382)
2.8 8.4 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
2.8 11.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
2.7 13.7 GO:0016476 regulation of embryonic cell shape(GO:0016476)
2.7 18.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
2.7 13.3 GO:0072642 interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
2.6 2.6 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
2.5 32.1 GO:0019388 galactose catabolic process(GO:0019388)
2.3 162.5 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
2.3 7.0 GO:0048382 mesendoderm development(GO:0048382)
2.3 25.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
2.3 13.8 GO:0006177 GMP biosynthetic process(GO:0006177)
2.3 18.2 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
2.3 9.1 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
2.2 15.7 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
2.2 37.6 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
2.2 28.7 GO:0038092 nodal signaling pathway(GO:0038092)
2.2 15.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
2.1 45.0 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
2.1 8.4 GO:0002326 B cell lineage commitment(GO:0002326)
2.1 12.4 GO:1901419 regulation of response to alcohol(GO:1901419)
2.1 45.5 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
2.1 18.5 GO:0071763 nuclear membrane organization(GO:0071763)
2.0 62.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
2.0 9.8 GO:0051182 coenzyme transport(GO:0051182)
2.0 5.9 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
1.9 29.2 GO:0006449 regulation of translational termination(GO:0006449)
1.9 40.9 GO:0006337 nucleosome disassembly(GO:0006337)
1.9 30.8 GO:0061684 chaperone-mediated autophagy(GO:0061684) regulation of chaperone-mediated autophagy(GO:1904714)
1.8 7.4 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
1.8 36.6 GO:0002021 response to dietary excess(GO:0002021)
1.8 27.3 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
1.8 12.6 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
1.8 42.9 GO:0097286 iron ion import(GO:0097286)
1.8 174.9 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
1.8 7.1 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
1.7 26.1 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
1.7 17.3 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
1.7 25.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
1.7 28.3 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
1.6 11.4 GO:0071896 protein localization to adherens junction(GO:0071896)
1.6 9.8 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
1.6 6.4 GO:1902410 mitotic cytokinetic process(GO:1902410)
1.6 6.4 GO:0019230 proprioception(GO:0019230)
1.6 18.7 GO:0006657 CDP-choline pathway(GO:0006657)
1.6 9.3 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
1.5 9.3 GO:0097167 circadian regulation of translation(GO:0097167)
1.5 29.1 GO:0050872 positive regulation of chromatin binding(GO:0035563) white fat cell differentiation(GO:0050872)
1.5 10.5 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
1.4 15.5 GO:2000210 positive regulation of anoikis(GO:2000210)
1.4 39.2 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
1.4 5.5 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
1.4 43.9 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
1.4 12.3 GO:0016584 nucleosome positioning(GO:0016584)
1.4 39.6 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
1.3 12.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
1.3 6.5 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
1.3 42.1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
1.3 35.6 GO:0032008 positive regulation of TOR signaling(GO:0032008)
1.3 12.6 GO:0001866 NK T cell proliferation(GO:0001866)
1.3 8.8 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
1.2 6.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
1.2 45.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
1.2 130.4 GO:0007062 sister chromatid cohesion(GO:0007062)
1.2 4.8 GO:0000103 sulfate assimilation(GO:0000103)
1.2 25.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
1.2 1.2 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
1.2 20.2 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
1.2 16.5 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
1.2 39.0 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
1.2 4.6 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
1.1 17.1 GO:0048853 forebrain morphogenesis(GO:0048853)
1.1 12.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
1.1 3.4 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
1.1 82.8 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
1.1 5.6 GO:2000035 positive regulation of somatic stem cell population maintenance(GO:1904674) regulation of stem cell division(GO:2000035)
1.1 45.6 GO:0051568 histone H3-K4 methylation(GO:0051568)
1.1 13.1 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
1.1 4.4 GO:0014038 regulation of Schwann cell differentiation(GO:0014038) positive regulation of Schwann cell differentiation(GO:0014040) response to cobalamin(GO:0033590)
1.1 6.5 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
1.1 10.9 GO:0016236 macroautophagy(GO:0016236)
1.1 72.6 GO:0070125 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
1.0 4.2 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
1.0 50.4 GO:0002181 cytoplasmic translation(GO:0002181)
1.0 29.7 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
1.0 32.6 GO:0006353 DNA-templated transcription, termination(GO:0006353)
1.0 8.9 GO:0006954 inflammatory response(GO:0006954)
1.0 3.8 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
1.0 4.8 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.9 47.9 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.9 11.6 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.9 4.4 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.9 3.4 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.8 3.4 GO:0015917 aminophospholipid transport(GO:0015917)
0.8 67.7 GO:0048208 vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.8 12.5 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.8 31.4 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.8 13.9 GO:0031935 regulation of chromatin silencing(GO:0031935)
0.8 17.6 GO:0032543 mitochondrial translation(GO:0032543)
0.8 7.9 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.8 10.8 GO:0048757 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.8 8.5 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.8 31.4 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.8 52.5 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439)
0.7 34.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.7 2.9 GO:1901805 glucosylceramide catabolic process(GO:0006680) beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.7 12.5 GO:0034453 microtubule anchoring(GO:0034453)
0.7 9.4 GO:0016180 snRNA processing(GO:0016180)
0.7 30.6 GO:0035329 hippo signaling(GO:0035329)
0.7 4.2 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.7 10.2 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.7 53.5 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.7 36.1 GO:0060416 response to growth hormone(GO:0060416)
0.7 7.8 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.6 1.9 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.6 12.6 GO:0002643 regulation of tolerance induction(GO:0002643)
0.6 27.0 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.6 1.2 GO:0007518 myoblast fate determination(GO:0007518)
0.6 20.8 GO:0005980 glycogen catabolic process(GO:0005980)
0.6 3.7 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.6 4.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.6 3.5 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.6 26.8 GO:0043171 peptide catabolic process(GO:0043171)
0.5 26.6 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.5 7.3 GO:0045815 positive regulation of gene expression, epigenetic(GO:0045815)
0.5 35.8 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.5 22.9 GO:0043277 apoptotic cell clearance(GO:0043277)
0.5 13.6 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.5 15.3 GO:0006517 protein deglycosylation(GO:0006517)
0.5 10.2 GO:0051290 protein heterotetramerization(GO:0051290)
0.5 33.6 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.5 145.3 GO:0008380 RNA splicing(GO:0008380)
0.5 20.3 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.5 6.8 GO:0097264 self proteolysis(GO:0097264)
0.5 11.3 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.4 9.8 GO:0007567 parturition(GO:0007567)
0.4 17.2 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.4 6.9 GO:0006071 glycerol metabolic process(GO:0006071)
0.4 36.2 GO:0045727 positive regulation of translation(GO:0045727)
0.4 29.6 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.3 14.2 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.3 6.7 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.3 28.1 GO:0007030 Golgi organization(GO:0007030)
0.3 1.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.3 8.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.3 14.8 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.3 0.8 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3 30.8 GO:0048675 axon extension(GO:0048675)
0.3 2.5 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.3 0.8 GO:0032912 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of transforming growth factor beta2 production(GO:0032912) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.2 2.2 GO:0015791 polyol transport(GO:0015791)
0.2 9.1 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.2 15.8 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.2 11.4 GO:0006397 mRNA processing(GO:0006397)
0.2 8.9 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.2 4.5 GO:0006446 regulation of translational initiation(GO:0006446)
0.2 11.9 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 3.8 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.1 2.8 GO:1901796 regulation of signal transduction by p53 class mediator(GO:1901796)
0.1 10.7 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1 0.4 GO:0021539 subthalamus development(GO:0021539)
0.1 9.0 GO:0070268 cornification(GO:0070268)
0.1 1.7 GO:0006937 regulation of muscle contraction(GO:0006937)
0.1 1.1 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.1 1.2 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 5.5 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 3.5 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.7 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0 0.2 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351) positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 1.0 GO:0016310 phosphorylation(GO:0016310)
0.0 2.1 GO:0017038 protein import(GO:0017038)
0.0 1.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 2.7 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.9 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 2.3 GO:0002576 platelet degranulation(GO:0002576)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
35.9 143.6 GO:1990423 RZZ complex(GO:1990423)
32.2 96.6 GO:0034455 t-UTP complex(GO:0034455)
31.7 126.6 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
26.5 265.5 GO:0000796 condensin complex(GO:0000796)
25.5 101.9 GO:0031417 NatC complex(GO:0031417)
21.2 381.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
15.7 94.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
14.5 72.6 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
14.2 255.3 GO:0034709 methylosome(GO:0034709)
14.0 42.1 GO:0030689 Noc complex(GO:0030689)
14.0 83.7 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
12.0 48.0 GO:1990246 uniplex complex(GO:1990246)
9.8 127.9 GO:0002199 zona pellucida receptor complex(GO:0002199)
8.6 128.6 GO:0044754 autolysosome(GO:0044754)
8.1 154.7 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
8.0 39.9 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
7.7 781.6 GO:0015935 small ribosomal subunit(GO:0015935)
7.4 51.8 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
7.3 58.1 GO:0034719 SMN-Sm protein complex(GO:0034719)
7.1 213.2 GO:0005680 anaphase-promoting complex(GO:0005680)
7.0 56.4 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
6.9 27.6 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
6.7 74.2 GO:0042788 polysomal ribosome(GO:0042788)
6.5 71.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
6.3 234.6 GO:0016592 mediator complex(GO:0016592)
6.3 31.4 GO:0032021 NELF complex(GO:0032021)
6.3 37.7 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
6.1 42.9 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
6.0 42.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
5.9 41.4 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
5.5 27.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
5.5 27.3 GO:0071986 Ragulator complex(GO:0071986)
5.4 37.9 GO:0000923 equatorial microtubule organizing center(GO:0000923)
5.4 59.4 GO:0044666 MLL3/4 complex(GO:0044666)
5.3 79.1 GO:0031080 nuclear pore outer ring(GO:0031080)
5.2 15.7 GO:0005826 actomyosin contractile ring(GO:0005826) GID complex(GO:0034657)
5.2 124.7 GO:0046930 pore complex(GO:0046930)
5.0 35.0 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
4.9 14.8 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
4.8 86.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
4.7 98.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
4.7 41.9 GO:0031298 replication fork protection complex(GO:0031298)
4.5 18.1 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
4.2 55.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
4.2 12.6 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
4.2 112.7 GO:0035145 exon-exon junction complex(GO:0035145)
4.1 37.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
4.1 12.3 GO:0031213 RSF complex(GO:0031213)
4.1 24.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
4.0 59.9 GO:0005641 nuclear envelope lumen(GO:0005641)
3.9 11.7 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
3.7 18.5 GO:0035061 interchromatin granule(GO:0035061)
3.7 14.8 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
3.5 60.0 GO:0045277 respiratory chain complex IV(GO:0045277)
3.5 379.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
3.5 35.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
3.5 31.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
3.4 85.1 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
3.3 26.7 GO:0000322 storage vacuole(GO:0000322)
3.3 45.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
3.3 19.5 GO:0008537 proteasome activator complex(GO:0008537)
3.1 24.5 GO:0042612 MHC class I protein complex(GO:0042612)
3.0 32.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
3.0 109.4 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
2.9 11.4 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
2.9 17.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
2.8 94.7 GO:0000421 autophagosome membrane(GO:0000421)
2.8 55.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
2.8 239.8 GO:0005840 ribosome(GO:0005840)
2.7 43.8 GO:0031616 spindle pole centrosome(GO:0031616)
2.7 134.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
2.6 186.9 GO:0005637 nuclear inner membrane(GO:0005637)
2.6 18.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
2.6 23.0 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
2.4 14.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
2.4 9.7 GO:0071817 MMXD complex(GO:0071817)
2.4 115.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
2.4 78.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
2.4 26.1 GO:0030123 AP-3 adaptor complex(GO:0030123)
2.4 42.7 GO:0033276 transcription factor TFTC complex(GO:0033276)
2.2 29.1 GO:0097470 ribbon synapse(GO:0097470)
2.2 204.5 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
2.2 37.6 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
2.2 4.4 GO:0071159 NF-kappaB complex(GO:0071159)
2.1 40.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
2.1 33.0 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
2.0 9.9 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
1.9 48.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
1.9 101.5 GO:0031941 filamentous actin(GO:0031941)
1.8 5.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
1.8 113.1 GO:0015030 Cajal body(GO:0015030)
1.8 5.3 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
1.7 10.4 GO:0005798 Golgi-associated vesicle(GO:0005798)
1.7 17.2 GO:0030126 COPI vesicle coat(GO:0030126)
1.7 20.6 GO:0030008 TRAPP complex(GO:0030008)
1.7 8.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
1.6 40.9 GO:0016514 SWI/SNF complex(GO:0016514)
1.6 48.0 GO:0030687 preribosome, large subunit precursor(GO:0030687)
1.6 4.7 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
1.5 72.7 GO:0002102 podosome(GO:0002102)
1.5 75.6 GO:0008180 COP9 signalosome(GO:0008180)
1.5 68.5 GO:0043034 costamere(GO:0043034)
1.5 24.4 GO:0030426 growth cone(GO:0030426)
1.5 12.1 GO:0000974 Prp19 complex(GO:0000974)
1.5 39.1 GO:0005844 polysome(GO:0005844)
1.5 7.5 GO:0042272 nuclear RNA export factor complex(GO:0042272)
1.5 28.3 GO:0036020 endolysosome membrane(GO:0036020)
1.5 5.9 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
1.4 11.2 GO:0005827 polar microtubule(GO:0005827)
1.4 109.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
1.4 235.8 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
1.4 13.9 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
1.4 8.3 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
1.4 12.4 GO:0072546 ER membrane protein complex(GO:0072546)
1.4 8.1 GO:0090543 Flemming body(GO:0090543)
1.3 31.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
1.2 3.7 GO:0005879 axonemal microtubule(GO:0005879)
1.2 13.3 GO:0008385 IkappaB kinase complex(GO:0008385)
1.1 15.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
1.1 2.2 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
1.1 43.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
1.1 11.6 GO:0005685 U1 snRNP(GO:0005685)
1.1 35.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
1.0 9.4 GO:0032039 integrator complex(GO:0032039)
1.0 106.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
1.0 24.4 GO:0034451 centriolar satellite(GO:0034451)
1.0 12.1 GO:0060077 inhibitory synapse(GO:0060077)
1.0 9.9 GO:0005869 dynactin complex(GO:0005869)
1.0 11.6 GO:0000815 ESCRT III complex(GO:0000815)
1.0 11.4 GO:0005916 fascia adherens(GO:0005916)
0.9 5.5 GO:0000124 SAGA complex(GO:0000124)
0.9 70.8 GO:0035578 azurophil granule lumen(GO:0035578)
0.8 10.8 GO:0031088 platelet dense granule membrane(GO:0031088)
0.8 78.8 GO:0005681 spliceosomal complex(GO:0005681)
0.8 7.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.8 104.3 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.8 311.0 GO:0016607 nuclear speck(GO:0016607)
0.8 61.7 GO:0031970 organelle envelope lumen(GO:0031970)
0.8 3.1 GO:0032044 DSIF complex(GO:0032044)
0.8 12.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.7 5.7 GO:0097443 sorting endosome(GO:0097443)
0.7 11.3 GO:0099738 cell cortex region(GO:0099738)
0.7 7.1 GO:0070187 telosome(GO:0070187)
0.7 266.9 GO:0010008 endosome membrane(GO:0010008)
0.6 53.6 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.6 3.4 GO:0016272 prefoldin complex(GO:0016272)
0.5 21.1 GO:0045178 basal part of cell(GO:0045178)
0.5 6.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.5 4.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.5 9.3 GO:0016363 nuclear matrix(GO:0016363)
0.5 133.8 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.4 4.4 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.4 6.9 GO:0000776 kinetochore(GO:0000776)
0.4 6.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.4 7.4 GO:0002080 acrosomal membrane(GO:0002080)
0.4 1.9 GO:0030897 HOPS complex(GO:0030897)
0.4 31.9 GO:0005814 centriole(GO:0005814)
0.4 6.1 GO:0097342 ripoptosome(GO:0097342)
0.4 18.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.3 3.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.3 7.5 GO:0045202 synapse(GO:0045202)
0.3 12.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.3 12.4 GO:0032155 cell division site(GO:0032153) cell division site part(GO:0032155)
0.3 93.9 GO:0005635 nuclear envelope(GO:0005635)
0.2 17.2 GO:0005874 microtubule(GO:0005874)
0.2 30.9 GO:0005938 cell cortex(GO:0005938)
0.2 138.2 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.2 16.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.2 12.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 6.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 36.1 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 5.4 GO:0031526 brush border membrane(GO:0031526)
0.1 4.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 23.8 GO:0005925 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.1 10.9 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 2.6 GO:0005811 lipid particle(GO:0005811)
0.1 1.1 GO:0098793 presynapse(GO:0098793)
0.1 30.9 GO:0030425 dendrite(GO:0030425)
0.1 9.5 GO:0098802 plasma membrane receptor complex(GO:0098802)
0.1 5.9 GO:0035579 specific granule membrane(GO:0035579)
0.1 1.4 GO:0031201 SNARE complex(GO:0031201)
0.1 1.7 GO:0005859 muscle myosin complex(GO:0005859)
0.0 21.5 GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network(GO:0042175)
0.0 28.4 GO:0005739 mitochondrion(GO:0005739)
0.0 0.8 GO:0005913 cell-cell adherens junction(GO:0005913)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
35.5 213.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
31.7 126.6 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
30.0 150.1 GO:0015140 malate transmembrane transporter activity(GO:0015140)
23.4 187.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
21.8 109.0 GO:0043023 ribosomal large subunit binding(GO:0043023)
21.3 42.7 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
20.6 144.4 GO:0050733 RS domain binding(GO:0050733)
19.6 195.6 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
18.5 55.5 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
17.9 71.6 GO:0043515 kinetochore binding(GO:0043515)
16.7 766.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
16.0 175.7 GO:0051525 NFAT protein binding(GO:0051525)
15.4 416.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
14.9 29.7 GO:0071987 WD40-repeat domain binding(GO:0071987)
14.8 44.4 GO:0004769 steroid delta-isomerase activity(GO:0004769)
14.3 42.9 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
13.5 94.3 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
13.3 106.5 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
12.8 38.4 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
12.1 109.2 GO:0015288 porin activity(GO:0015288)
12.1 72.6 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
10.7 32.1 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
10.5 41.9 GO:0036033 mediator complex binding(GO:0036033)
10.2 30.7 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
9.9 49.7 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
9.5 47.6 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
8.9 44.3 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
8.3 75.0 GO:0033592 RNA strand annealing activity(GO:0033592)
8.2 115.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
8.0 39.9 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
7.8 23.5 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
7.8 39.2 GO:0004906 interferon-gamma receptor activity(GO:0004906)
7.6 53.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
7.0 20.9 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
7.0 41.7 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
6.7 40.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
6.6 19.9 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
6.6 72.6 GO:0000150 recombinase activity(GO:0000150)
6.5 103.2 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
6.4 32.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
6.3 56.4 GO:0008312 7S RNA binding(GO:0008312)
6.2 37.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
6.1 84.9 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
6.0 23.8 GO:0003990 acetylcholinesterase activity(GO:0003990)
5.7 22.9 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
5.2 15.5 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
5.1 25.4 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
5.0 146.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
5.0 169.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
4.9 14.8 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
4.9 14.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
4.8 164.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
4.8 129.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
4.7 18.7 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
4.6 27.6 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
4.4 35.4 GO:0090599 alpha-glucosidase activity(GO:0090599)
4.2 12.6 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
4.2 29.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
4.1 37.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
4.1 24.5 GO:0046979 TAP2 binding(GO:0046979)
3.8 11.4 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
3.4 78.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
3.4 17.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
3.3 666.4 GO:0003735 structural constituent of ribosome(GO:0003735)
3.3 13.3 GO:0008384 IkappaB kinase activity(GO:0008384)
3.3 9.9 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
3.3 9.8 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
3.2 12.9 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
3.2 19.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
3.1 52.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
3.1 9.3 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
3.1 46.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
3.0 12.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
3.0 35.7 GO:0089720 caspase binding(GO:0089720)
2.9 111.9 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
2.8 138.9 GO:0043022 ribosome binding(GO:0043022)
2.8 11.2 GO:0031208 POZ domain binding(GO:0031208)
2.8 19.5 GO:0061133 endopeptidase activator activity(GO:0061133)
2.6 13.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
2.6 91.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
2.6 10.2 GO:0004074 biliverdin reductase activity(GO:0004074)
2.5 7.5 GO:0034046 poly(G) binding(GO:0034046)
2.5 62.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
2.5 17.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
2.4 61.4 GO:0042288 MHC class I protein binding(GO:0042288)
2.3 18.5 GO:0019237 centromeric DNA binding(GO:0019237)
2.2 31.0 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
2.2 39.6 GO:0008327 methyl-CpG binding(GO:0008327)
2.1 10.6 GO:0097322 7SK snRNA binding(GO:0097322)
2.0 37.6 GO:0000400 four-way junction DNA binding(GO:0000400)
2.0 81.2 GO:0004407 histone deacetylase activity(GO:0004407)
1.9 94.5 GO:0048487 beta-tubulin binding(GO:0048487)
1.9 122.3 GO:0050681 androgen receptor binding(GO:0050681)
1.9 49.0 GO:0043015 gamma-tubulin binding(GO:0043015)
1.8 31.3 GO:0001056 RNA polymerase III activity(GO:0001056)
1.8 7.3 GO:0004920 interleukin-10 receptor activity(GO:0004920)
1.8 9.0 GO:0048039 ubiquinone binding(GO:0048039)
1.8 197.1 GO:0003697 single-stranded DNA binding(GO:0003697)
1.8 116.2 GO:0031491 nucleosome binding(GO:0031491)
1.7 35.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
1.7 6.8 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
1.7 8.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
1.7 8.4 GO:0070644 vitamin D response element binding(GO:0070644)
1.7 6.7 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
1.6 9.9 GO:0019776 Atg8 ligase activity(GO:0019776)
1.6 4.8 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
1.6 12.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
1.6 12.4 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
1.5 4.6 GO:0035033 histone deacetylase regulator activity(GO:0035033)
1.5 22.9 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
1.5 19.5 GO:0008641 small protein activating enzyme activity(GO:0008641)
1.4 37.5 GO:0030515 snoRNA binding(GO:0030515)
1.4 4.2 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
1.4 21.1 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
1.4 13.9 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
1.4 4.2 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
1.4 12.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
1.4 64.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
1.3 95.2 GO:0009055 electron carrier activity(GO:0009055)
1.3 7.9 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
1.3 14.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
1.3 68.8 GO:0016831 carboxy-lyase activity(GO:0016831)
1.3 33.3 GO:0070410 co-SMAD binding(GO:0070410)
1.3 11.4 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
1.3 7.5 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
1.2 16.1 GO:0008494 translation activator activity(GO:0008494)
1.2 13.0 GO:0039706 co-receptor binding(GO:0039706)
1.2 25.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
1.2 26.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
1.1 13.6 GO:0031386 protein tag(GO:0031386)
1.1 4.4 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
1.1 33.0 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
1.1 17.1 GO:0070628 proteasome binding(GO:0070628)
1.0 53.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
1.0 14.0 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
1.0 113.7 GO:0008565 protein transporter activity(GO:0008565)
1.0 40.7 GO:0000049 tRNA binding(GO:0000049)
0.9 53.4 GO:0035064 methylated histone binding(GO:0035064)
0.9 23.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.9 5.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.8 15.5 GO:0051400 BH domain binding(GO:0051400)
0.8 6.4 GO:0016301 kinase activity(GO:0016301)
0.8 2.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.8 20.3 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.7 2.9 GO:0004348 glucosylceramidase activity(GO:0004348)
0.7 4.4 GO:0071532 ankyrin repeat binding(GO:0071532)
0.7 46.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.7 65.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.7 9.3 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.7 11.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.6 18.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.6 22.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.6 14.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.6 76.1 GO:0005262 calcium channel activity(GO:0005262)
0.6 13.5 GO:0005521 lamin binding(GO:0005521)
0.6 6.2 GO:0097016 L27 domain binding(GO:0097016)
0.5 44.2 GO:0032947 protein complex scaffold(GO:0032947)
0.5 45.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.5 15.4 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.5 14.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.5 12.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.5 9.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.5 37.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.5 72.5 GO:0017124 SH3 domain binding(GO:0017124)
0.5 3.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.5 5.3 GO:0019783 ubiquitin-like protein-specific protease activity(GO:0019783)
0.5 651.3 GO:0003723 RNA binding(GO:0003723)
0.4 115.4 GO:0045296 cadherin binding(GO:0045296)
0.4 1.3 GO:0031685 adenosine receptor binding(GO:0031685)
0.4 8.0 GO:0097602 cullin family protein binding(GO:0097602)
0.4 34.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.4 38.2 GO:0005525 GTP binding(GO:0005525)
0.4 2.2 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.3 8.7 GO:0030507 spectrin binding(GO:0030507)
0.3 2.0 GO:0016018 cyclosporin A binding(GO:0016018)
0.3 93.9 GO:0003924 GTPase activity(GO:0003924)
0.3 6.5 GO:0030331 estrogen receptor binding(GO:0030331)
0.3 13.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.3 1.1 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.2 4.2 GO:0097200 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.2 17.5 GO:0042393 histone binding(GO:0042393)
0.2 6.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 2.4 GO:0009881 photoreceptor activity(GO:0009881)
0.1 3.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 3.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 86.2 GO:0042803 protein homodimerization activity(GO:0042803)
0.1 10.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 1.8 GO:0019239 deaminase activity(GO:0019239)
0.1 0.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 3.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 3.5 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 0.6 GO:0043621 protein self-association(GO:0043621)
0.1 1.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 32.9 GO:0005509 calcium ion binding(GO:0005509)
0.1 6.0 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.8 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 2.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.2 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
16.0 671.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
5.1 167.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
4.9 317.3 PID AURORA B PATHWAY Aurora B signaling
4.5 18.1 PID BARD1 PATHWAY BARD1 signaling events
4.0 239.9 PID PLK1 PATHWAY PLK1 signaling events
3.1 91.9 PID WNT SIGNALING PATHWAY Wnt signaling network
2.9 145.5 PID ATR PATHWAY ATR signaling pathway
2.4 82.5 PID AVB3 OPN PATHWAY Osteopontin-mediated events
2.4 78.7 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
2.1 84.9 PID VEGFR1 PATHWAY VEGFR1 specific signals
2.1 220.2 PID AR PATHWAY Coregulation of Androgen receptor activity
2.0 108.1 PID HES HEY PATHWAY Notch-mediated HES/HEY network
1.9 95.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
1.5 35.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
1.3 53.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
1.2 81.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
1.1 89.0 PID E2F PATHWAY E2F transcription factor network
1.1 23.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
1.0 38.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
1.0 15.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
1.0 12.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.9 86.0 PID CMYB PATHWAY C-MYB transcription factor network
0.9 32.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.9 3.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.9 6.0 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.8 50.2 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.8 22.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.8 25.0 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.8 25.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.7 42.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.5 29.2 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.4 28.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.4 30.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.4 15.2 PID P53 REGULATION PATHWAY p53 pathway
0.3 17.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.3 11.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.2 10.8 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.2 14.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.2 2.6 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.2 8.1 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.2 7.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.2 44.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 2.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.2 9.3 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.2 6.7 PID BCR 5PATHWAY BCR signaling pathway
0.2 8.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.2 8.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 6.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 2.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 6.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 1.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
18.7 692.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
18.4 424.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
10.8 303.1 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
10.2 183.6 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
9.1 145.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
7.1 537.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
6.3 94.3 REACTOME POL SWITCHING Genes involved in Polymerase switching
6.0 72.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
4.8 126.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
4.6 480.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
4.5 245.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
4.4 35.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
4.3 12.9 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
4.1 86.9 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
4.1 127.9 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
4.1 190.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
4.0 145.1 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
3.8 37.9 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
3.6 32.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
3.5 51.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
3.4 64.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
3.3 274.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
3.3 253.9 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
3.2 44.8 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
3.2 12.8 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
3.0 108.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
3.0 29.8 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
2.9 72.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
2.8 5.5 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
2.8 146.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
2.6 82.1 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
2.4 23.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
2.2 60.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
2.2 17.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
2.1 59.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
2.1 38.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
1.9 23.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
1.9 123.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
1.9 161.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
1.9 44.9 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
1.8 56.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
1.7 69.9 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
1.6 9.8 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
1.5 38.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
1.5 27.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
1.3 42.9 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
1.2 28.2 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
1.1 11.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
1.1 13.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
1.1 74.5 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
1.0 28.3 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
1.0 9.1 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
1.0 18.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
1.0 23.4 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
1.0 14.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
1.0 18.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.9 15.0 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.9 23.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.9 99.8 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.8 13.8 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.7 26.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.7 20.8 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.7 22.9 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.7 86.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.7 40.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.6 7.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.6 15.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.6 15.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.5 14.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.5 34.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.4 29.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.4 8.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.4 20.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.4 10.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.4 3.4 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.4 7.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.4 9.9 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.3 6.9 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.3 58.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.3 11.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.3 40.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.3 2.7 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.3 4.4 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.3 5.9 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.3 5.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.3 4.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.3 5.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 4.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.2 4.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 6.8 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 8.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 2.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 3.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 4.9 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 2.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 5.4 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events