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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ZBTB6

Z-value: 1.40

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Transcription factors associated with ZBTB6

Gene Symbol Gene ID Gene Info
ENSG00000186130.4 zinc finger and BTB domain containing 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB6hg19_v2_chr9_-_125675576_1256756120.212.2e-03Click!

Activity profile of ZBTB6 motif

Sorted Z-values of ZBTB6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_204380919 37.92 ENST00000367188.4
protein phosphatase 1, regulatory subunit 15B
chr8_+_104513086 21.31 ENST00000406091.3
regulating synaptic membrane exocytosis 2
chr3_-_133614421 21.06 ENST00000543906.1
RAB6B, member RAS oncogene family
chr17_+_26684604 20.97 ENST00000292114.3
ENST00000509083.1
transmembrane protein 199
chr9_+_137979506 20.88 ENST00000539529.1
ENST00000392991.4
ENST00000371793.3
olfactomedin 1
chr22_-_39239987 19.95 ENST00000333039.2
neuronal pentraxin receptor
chr11_-_12030905 19.44 ENST00000326932.4
dickkopf WNT signaling pathway inhibitor 3
chr14_-_81687197 18.20 ENST00000553612.1
general transcription factor IIA, 1, 19/37kDa
chr2_-_38604398 17.26 ENST00000443098.1
ENST00000449130.1
ENST00000378954.4
ENST00000539122.1
ENST00000419554.2
ENST00000451483.1
ENST00000406122.1
atlastin GTPase 2
chr1_+_11866270 16.59 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
chloride channel, voltage-sensitive 6
chr8_-_67341208 16.58 ENST00000499642.1
RP11-346I3.4
chr6_-_46459675 16.28 ENST00000306764.7
regulator of calcineurin 2
chr7_+_100136811 16.15 ENST00000300176.4
ENST00000262935.4
ArfGAP with FG repeats 2
chr16_+_2039946 16.12 ENST00000248121.2
ENST00000568896.1
synaptogyrin 3
chr12_-_111021110 15.73 ENST00000354300.3
PTC7 protein phosphatase homolog (S. cerevisiae)
chr16_+_28834531 15.67 ENST00000570200.1
ataxin 2-like
chr1_+_233086326 15.15 ENST00000366628.5
ENST00000366627.4
nucleoside-triphosphatase, cancer-related
chr17_-_1733114 14.96 ENST00000305513.7
SET and MYND domain containing 4
chr20_-_48532019 14.89 ENST00000289431.5
spermatogenesis associated 2
chr14_-_60337684 14.78 ENST00000267484.5
reticulon 1
chr14_-_81687575 14.71 ENST00000434192.2
general transcription factor IIA, 1, 19/37kDa
chr20_-_62129163 14.49 ENST00000298049.7
eukaryotic translation elongation factor 1 alpha 2
chr12_-_133707021 14.48 ENST00000537226.1
zinc finger protein 891
chr1_-_11865982 14.35 ENST00000418034.1
methylenetetrahydrofolate reductase (NAD(P)H)
chr11_-_12030629 14.35 ENST00000396505.2
dickkopf WNT signaling pathway inhibitor 3
chr2_+_111490161 13.73 ENST00000340561.4
acyl-CoA oxidase-like
chr16_+_22825475 13.57 ENST00000261374.3
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr2_+_220492373 13.29 ENST00000317151.3
solute carrier family 4 (anion exchanger), member 3
chr16_+_1756162 13.08 ENST00000250894.4
ENST00000356010.5
mitogen-activated protein kinase 8 interacting protein 3
chr22_-_38699003 12.92 ENST00000451964.1
casein kinase 1, epsilon
chr1_+_16062820 12.74 ENST00000294454.5
solute carrier family 25, member 34
chr6_+_71122974 12.59 ENST00000418814.2
family with sequence similarity 135, member A
chr19_+_54058073 12.54 ENST00000505949.1
ENST00000513265.1
zinc finger protein 331
chr9_+_87284622 12.51 ENST00000395882.1
neurotrophic tyrosine kinase, receptor, type 2
chr6_-_33168391 12.50 ENST00000374685.4
ENST00000413614.2
ENST00000374680.3
retinoid X receptor, beta
chr3_-_194991876 12.41 ENST00000310380.6
xyloside xylosyltransferase 1
chr14_-_50999190 12.30 ENST00000557390.1
mitogen-activated protein kinase kinase kinase kinase 5
chr6_+_71123107 12.25 ENST00000370479.3
ENST00000505769.1
ENST00000515323.1
ENST00000515280.1
ENST00000507085.1
ENST00000457062.2
ENST00000361499.3
family with sequence similarity 135, member A
chr6_+_41040678 12.16 ENST00000341376.6
ENST00000353205.5
nuclear transcription factor Y, alpha
chr15_+_64752927 12.05 ENST00000416172.1
zinc finger protein 609
chr9_+_137967366 11.95 ENST00000252854.4
olfactomedin 1
chr3_-_133614597 11.91 ENST00000285208.4
ENST00000460865.3
RAB6B, member RAS oncogene family
chr16_+_28834303 11.85 ENST00000340394.8
ENST00000325215.6
ENST00000395547.2
ENST00000336783.4
ENST00000382686.4
ENST00000564304.1
ataxin 2-like
chr17_-_42402138 11.74 ENST00000592857.1
ENST00000586016.1
ENST00000590194.1
ENST00000377095.5
ENST00000588049.1
ENST00000586633.1
ENST00000537904.2
ENST00000585636.1
ENST00000585523.1
ENST00000225308.8
solute carrier family 25, member 39
chr5_-_131892501 11.60 ENST00000450655.1
interleukin 5 (colony-stimulating factor, eosinophil)
chr19_-_49945617 11.51 ENST00000600601.1
ENST00000543531.1
solute carrier family 17 (vesicular glutamate transporter), member 7
chr17_+_80416482 11.45 ENST00000309794.11
ENST00000345415.7
ENST00000457415.3
ENST00000584411.1
ENST00000412079.2
ENST00000577432.1
nuclear prelamin A recognition factor
chr16_+_56225248 11.41 ENST00000262493.6
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chrX_+_44732757 11.36 ENST00000377967.4
ENST00000536777.1
ENST00000382899.4
ENST00000543216.1
lysine (K)-specific demethylase 6A
chr6_+_42847348 11.36 ENST00000493763.1
ENST00000304734.5
ribosomal protein L7-like 1
chr12_-_52887034 11.33 ENST00000330722.6
keratin 6A
chr19_+_42817527 11.28 ENST00000598766.1
transmembrane protein 145
chr8_-_145159083 11.28 ENST00000398712.2
SHANK-associated RH domain interactor
chr10_-_15413035 10.98 ENST00000378116.4
ENST00000455654.1
family with sequence similarity 171, member A1
chr17_+_40688190 10.89 ENST00000225927.2
N-acetylglucosaminidase, alpha
chr11_+_82868030 10.88 ENST00000298281.4
ENST00000530660.1
PCF11 cleavage and polyadenylation factor subunit
chr11_+_92085707 10.82 ENST00000525166.1
FAT atypical cadherin 3
chr9_+_34958254 10.81 ENST00000242315.3
KIAA1045
chr1_+_151043070 10.77 ENST00000368918.3
ENST00000368917.1
GA binding protein transcription factor, beta subunit 2
chr19_-_58326267 10.67 ENST00000391701.1
zinc finger protein 552
chr12_-_54982300 10.64 ENST00000547431.1
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr22_-_21213029 10.54 ENST00000572273.1
ENST00000255882.6
phosphatidylinositol 4-kinase, catalytic, alpha
chr15_-_83378638 10.46 ENST00000261722.3
adaptor-related protein complex 3, beta 2 subunit
chr5_+_178368186 10.26 ENST00000320129.3
ENST00000519564.1
zinc finger protein 454
chr5_-_140998481 10.23 ENST00000518047.1
diaphanous-related formin 1
chr2_+_220492287 10.18 ENST00000273063.6
ENST00000373762.3
solute carrier family 4 (anion exchanger), member 3
chr4_+_41258786 10.17 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr16_+_50775948 10.16 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
cylindromatosis (turban tumor syndrome)
chr17_+_48610074 10.10 ENST00000503690.1
ENST00000514874.1
ENST00000537145.1
ENST00000541226.1
epsin 3
chr7_-_100823496 10.08 ENST00000455377.1
ENST00000443096.1
ENST00000300303.2
N-acetyltransferase 16 (GCN5-related, putative)
chr17_+_7184986 10.07 ENST00000317370.8
ENST00000571308.1
solute carrier family 2 (facilitated glucose transporter), member 4
chr7_+_138916231 9.99 ENST00000473989.3
ENST00000288561.8
ubinuclein 2
chr8_-_21646311 9.98 ENST00000524240.1
ENST00000400782.4
GDNF family receptor alpha 2
chr17_+_4046462 9.96 ENST00000577075.2
ENST00000575251.1
ENST00000301391.3
cytochrome b5 domain containing 2
chrX_+_21857764 9.93 ENST00000365779.2
membrane-bound transcription factor peptidase, site 2
chrX_-_92928557 9.69 ENST00000373079.3
ENST00000475430.2
nucleosome assembly protein 1-like 3
chr2_+_220492116 9.58 ENST00000373760.2
solute carrier family 4 (anion exchanger), member 3
chr22_-_20104700 9.49 ENST00000439169.2
ENST00000445045.1
ENST00000404751.3
ENST00000252136.7
ENST00000403707.3
tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr6_+_149068464 9.16 ENST00000367463.4
uronyl-2-sulfotransferase
chr10_-_75571566 9.16 ENST00000299641.4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr9_+_126773880 9.07 ENST00000373615.4
LIM homeobox 2
chr17_-_27278304 9.03 ENST00000577226.1
PHD finger protein 12
chr3_+_128720424 8.92 ENST00000480450.1
ENST00000436022.2
EF-hand and coiled-coil domain containing 1
chrX_+_30671476 8.83 ENST00000378946.3
ENST00000378943.3
ENST00000378945.3
ENST00000427190.1
ENST00000378941.3
glycerol kinase
chr19_-_42746714 8.78 ENST00000222330.3
glycogen synthase kinase 3 alpha
chrY_-_15591485 8.71 ENST00000382896.4
ENST00000537580.1
ENST00000540140.1
ENST00000545955.1
ENST00000538878.1
ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
chr5_+_17217669 8.68 ENST00000322611.3
brain abundant, membrane attached signal protein 1
chr16_-_4897266 8.61 ENST00000591451.1
ENST00000436648.5
ENST00000381983.3
ENST00000588297.1
ENST00000321919.9
glyoxylate reductase 1 homolog (Arabidopsis)
chr12_+_130822417 8.55 ENST00000245255.3
piwi-like RNA-mediated gene silencing 1
chr5_+_140220769 8.46 ENST00000531613.1
ENST00000378123.3
protocadherin alpha 8
chr7_-_102158157 8.45 ENST00000541662.1
ENST00000306682.6
ENST00000465829.1
RAS p21 protein activator 4B
chr4_+_56814968 8.36 ENST00000422247.2
centrosomal protein 135kDa
chr17_-_7518145 8.33 ENST00000250113.7
ENST00000571597.1
fragile X mental retardation, autosomal homolog 2
chr1_-_115212640 8.32 ENST00000393274.1
DENN/MADD domain containing 2C
chr17_+_34958001 8.30 ENST00000250156.7
mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
chr12_+_56401268 8.27 ENST00000262032.5
IKAROS family zinc finger 4 (Eos)
chr6_-_6007200 8.26 ENST00000244766.2
neuritin 1
chr2_-_237076992 8.25 ENST00000306318.4
gastrulation brain homeobox 2
chr7_+_4721885 8.25 ENST00000328914.4
forkhead box K1
chr4_+_1795508 8.22 ENST00000260795.2
ENST00000352904.1
fibroblast growth factor receptor 3
chr22_+_20104947 8.19 ENST00000402752.1
RAN binding protein 1
chrY_+_6114264 8.13 ENST00000320701.4
ENST00000383042.1
testis specific protein, Y-linked 2
chr2_+_220491973 8.11 ENST00000358055.3
solute carrier family 4 (anion exchanger), member 3
chr11_-_65686496 8.07 ENST00000449692.3
chromosome 11 open reading frame 68
chr2_-_37193606 8.05 ENST00000379213.2
ENST00000263918.4
striatin, calmodulin binding protein
chr3_-_120068143 8.04 ENST00000295628.3
leucine rich repeat containing 58
chr15_+_85144217 8.01 ENST00000540936.1
ENST00000448803.2
ENST00000546275.1
ENST00000546148.1
ENST00000442073.3
ENST00000334141.3
ENST00000358472.3
ENST00000502939.2
ENST00000379358.3
ENST00000327179.6
zinc finger and SCAN domain containing 2
chr10_-_75571341 7.98 ENST00000309979.6
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr15_-_64126084 7.97 ENST00000560316.1
ENST00000443617.2
ENST00000560462.1
ENST00000558532.1
ENST00000561400.1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr5_-_141257954 7.94 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
protocadherin 1
chr5_+_149546334 7.92 ENST00000231656.8
caudal type homeobox 1
chr1_-_17445930 7.92 ENST00000375486.4
ENST00000375481.1
ENST00000444885.2
peptidyl arginine deiminase, type II
chr5_+_170288856 7.90 ENST00000523189.1
RAN binding protein 17
chr12_+_6930813 7.88 ENST00000428545.2
G protein-coupled receptor 162
chr22_+_38004832 7.86 ENST00000405147.3
ENST00000429218.1
ENST00000325180.8
ENST00000337437.4
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr19_-_19843900 7.81 ENST00000344099.3
zinc finger protein 14
chr13_-_50510434 7.81 ENST00000361840.3
SPRY domain containing 7
chr20_+_23016057 7.79 ENST00000255008.3
somatostatin receptor 4
chr3_+_14989186 7.78 ENST00000435454.1
ENST00000323373.6
nuclear receptor subfamily 2, group C, member 2
chr14_-_103987679 7.74 ENST00000553610.1
creatine kinase, brain
chr17_+_40118805 7.73 ENST00000591072.1
ENST00000587679.1
ENST00000393888.1
ENST00000441615.2
2',3'-cyclic nucleotide 3' phosphodiesterase
chr4_+_1795012 7.73 ENST00000481110.2
ENST00000340107.4
ENST00000440486.2
ENST00000412135.2
fibroblast growth factor receptor 3
chr19_-_49137790 7.66 ENST00000599385.1
D site of albumin promoter (albumin D-box) binding protein
chrX_-_106960285 7.64 ENST00000503515.1
ENST00000372397.2
TSC22 domain family, member 3
chr3_-_138725110 7.62 ENST00000383163.2
proline rich 23A
chr19_-_49576198 7.60 ENST00000221444.1
potassium voltage-gated channel, shaker-related subfamily, member 7
chr17_+_80416050 7.56 ENST00000579198.1
ENST00000390006.4
ENST00000580296.1
nuclear prelamin A recognition factor
chr19_-_49149553 7.55 ENST00000084798.4
carbonic anhydrase XI
chr17_+_47572647 7.42 ENST00000172229.3
nerve growth factor receptor
chr13_+_88324870 7.41 ENST00000325089.6
SLIT and NTRK-like family, member 5
chrY_+_9304564 7.41 ENST00000451548.1
testis specific protein, Y-linked 1
chr6_-_34113856 7.39 ENST00000538487.2
glutamate receptor, metabotropic 4
chr20_+_44509857 7.36 ENST00000372523.1
ENST00000372520.1
zinc finger, SWIM-type containing 1
chr19_+_48867652 7.36 ENST00000344846.2
synaptogyrin 4
chr3_+_10857885 7.35 ENST00000254488.2
ENST00000454147.1
solute carrier family 6 (neurotransmitter transporter), member 11
chr11_-_64410787 7.35 ENST00000301894.2
neurexin 2
chr6_-_119399895 7.31 ENST00000338891.7
family with sequence similarity 184, member A
chr5_+_177557997 7.29 ENST00000313386.4
ENST00000515098.1
ENST00000542098.1
ENST00000502814.1
ENST00000507457.1
ENST00000508647.1
required for meiotic nuclear division 5 homolog B (S. cerevisiae)
chr17_-_4890919 7.25 ENST00000572543.1
ENST00000381311.5
ENST00000348066.3
ENST00000358183.4
calmodulin binding transcription activator 2
chr11_-_62359027 7.21 ENST00000494385.1
ENST00000308436.7
terminal uridylyl transferase 1, U6 snRNA-specific
chr2_+_166095898 7.21 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
sodium channel, voltage-gated, type II, alpha subunit
chr4_+_159131346 7.17 ENST00000508243.1
ENST00000296529.6
transmembrane protein 144
chr10_+_47746929 7.15 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
annexin A8-like 2
Protein LOC100996760
chr9_+_841690 7.14 ENST00000382276.3
doublesex and mab-3 related transcription factor 1
chr12_+_6930703 7.14 ENST00000311268.3
G protein-coupled receptor 162
chr14_+_101302041 7.11 ENST00000522618.1
maternally expressed 3 (non-protein coding)
chr22_+_41865109 7.11 ENST00000216254.4
ENST00000396512.3
aconitase 2, mitochondrial
chr19_-_12444491 7.11 ENST00000293725.5
zinc finger protein 563
chr14_+_105781048 7.07 ENST00000458164.2
ENST00000447393.1
phosphofurin acidic cluster sorting protein 2
chr9_-_123691047 7.06 ENST00000373887.3
TNF receptor-associated factor 1
chr11_+_68228186 7.05 ENST00000393799.2
ENST00000393800.2
ENST00000528635.1
ENST00000533127.1
ENST00000529907.1
ENST00000529344.1
ENST00000534534.1
ENST00000524845.1
ENST00000265637.4
ENST00000524904.1
ENST00000393801.3
ENST00000265636.5
ENST00000529710.1
protein phosphatase 6, regulatory subunit 3
chr7_-_17980091 7.02 ENST00000409389.1
ENST00000409604.1
ENST00000428135.3
sorting nexin 13
chr16_+_50775971 7.01 ENST00000311559.9
ENST00000564326.1
ENST00000566206.1
cylindromatosis (turban tumor syndrome)
chr16_+_4897632 6.98 ENST00000262376.6
ubinuclein 1
chr1_-_223537401 6.93 ENST00000343846.3
ENST00000454695.2
ENST00000484758.2
sushi domain containing 4
chr15_+_71185148 6.93 ENST00000443425.2
ENST00000560755.1
leucine rich repeat containing 49
chrX_+_21857717 6.85 ENST00000379484.5
membrane-bound transcription factor peptidase, site 2
chr15_+_43809797 6.83 ENST00000399453.1
ENST00000300231.5
microtubule-associated protein 1A
chr1_+_46972668 6.82 ENST00000371956.4
ENST00000360032.3
diencephalon/mesencephalon homeobox 1
chr12_-_52845910 6.82 ENST00000252252.3
keratin 6B
chr1_+_184356188 6.81 ENST00000235307.6
chromosome 1 open reading frame 21
chr12_+_69864129 6.80 ENST00000547219.1
ENST00000299293.2
ENST00000549921.1
ENST00000550316.1
ENST00000548154.1
ENST00000547414.1
ENST00000550389.1
ENST00000550937.1
ENST00000549092.1
ENST00000550169.1
fibroblast growth factor receptor substrate 2
chrY_+_9175073 6.77 ENST00000426950.2
ENST00000383008.1
testis specific protein, Y-linked 4
chr19_-_45663408 6.74 ENST00000317951.4
NTPase, KAP family P-loop domain containing 1
chr2_+_148602058 6.71 ENST00000241416.7
ENST00000535787.1
ENST00000404590.1
activin A receptor, type IIA
chr2_-_25896380 6.67 ENST00000545439.1
ENST00000407186.1
ENST00000406818.3
ENST00000404103.3
ENST00000407661.3
ENST00000407038.3
ENST00000405222.1
ENST00000288642.8
dystrobrevin, beta
chr1_-_233431458 6.67 ENST00000258229.9
ENST00000430153.1
pecanex-like 2 (Drosophila)
chr1_+_151171012 6.66 ENST00000349792.5
ENST00000409426.1
ENST00000441902.2
ENST00000368890.4
ENST00000424999.1
ENST00000368888.4
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
chr1_-_236445251 6.64 ENST00000354619.5
ENST00000327333.8
ERO1-like beta (S. cerevisiae)
chr10_+_120789223 6.62 ENST00000425699.1
nanos homolog 1 (Drosophila)
chr19_-_3971050 6.62 ENST00000545797.2
ENST00000596311.1
death-associated protein kinase 3
chr19_+_57999079 6.61 ENST00000426954.2
ENST00000354197.4
ENST00000523882.1
ENST00000520540.1
ENST00000519310.1
ENST00000442920.2
ENST00000523312.1
ENST00000424930.2
zinc finger protein 419
chr12_+_6930964 6.60 ENST00000382315.3
G protein-coupled receptor 162
chr1_+_152957707 6.60 ENST00000368762.1
small proline-rich protein 1A
chr19_+_4304632 6.58 ENST00000597590.1
fibronectin type III and SPRY domain containing 1
chr8_+_38089198 6.56 ENST00000528358.1
ENST00000529642.1
ENST00000532222.1
ENST00000520272.2
DDHD domain containing 2
chr13_-_50510622 6.56 ENST00000378195.2
SPRY domain containing 7
chr15_+_43886057 6.52 ENST00000441322.1
ENST00000413657.2
ENST00000453733.1
creatine kinase, mitochondrial 1B
chr7_+_94537542 6.51 ENST00000433881.1
protein phosphatase 1, regulatory subunit 9A
chr19_+_57999101 6.51 ENST00000347466.6
ENST00000523138.1
ENST00000415379.2
ENST00000521754.1
ENST00000221735.7
ENST00000518999.1
ENST00000521137.1
zinc finger protein 419
chr1_+_15272271 6.50 ENST00000400797.3
kazrin, periplakin interacting protein
chr19_-_49137762 6.49 ENST00000593500.1
D site of albumin promoter (albumin D-box) binding protein
chr4_-_122791583 6.48 ENST00000506636.1
ENST00000264499.4
Bardet-Biedl syndrome 7
chr11_+_123396528 6.47 ENST00000322282.7
ENST00000529750.1
GRAM domain containing 1B
chr21_-_34100244 6.45 ENST00000382491.3
ENST00000357345.3
ENST00000429236.1
synaptojanin 1
chr21_+_47878757 6.43 ENST00000400274.1
ENST00000427143.2
ENST00000318711.7
ENST00000457905.3
ENST00000466639.1
ENST00000435722.3
ENST00000417564.2
DIP2 disco-interacting protein 2 homolog A (Drosophila)
chr6_-_34073743 6.43 ENST00000609222.1
glutamate receptor, metabotropic 4
chr16_+_28835437 6.43 ENST00000568266.1
ataxin 2-like
chr4_+_140374961 6.42 ENST00000305626.5
RAB33B, member RAS oncogene family
chr11_+_46299199 6.42 ENST00000529193.1
ENST00000288400.3
cAMP responsive element binding protein 3-like 1
chr13_+_28712614 6.40 ENST00000380958.3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr10_-_47173994 6.39 ENST00000414655.2
ENST00000545298.1
ENST00000359178.4
ENST00000358140.4
ENST00000503031.1
annexin A8-like 1
long intergenic non-protein coding RNA 842
chrY_-_24329095 6.32 ENST00000303766.7
ENST00000454978.2
RNA binding motif protein, Y-linked, family 1, member F
chr17_-_76836729 6.30 ENST00000587783.1
ENST00000542802.3
ENST00000586531.1
ENST00000589424.1
ENST00000590546.2
ubiquitin specific peptidase 36
chr7_+_44143925 6.26 ENST00000223357.3
AE binding protein 1
chr10_+_48255253 6.22 ENST00000357718.4
ENST00000344416.5
ENST00000456111.2
ENST00000374258.3
annexin A8
Protein LOC100996760
chr11_-_6677018 6.21 ENST00000299441.3
dachsous cadherin-related 1
chr19_-_51920952 6.21 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
sialic acid binding Ig-like lectin 10
chr11_+_118938485 6.13 ENST00000300793.6
vacuolar protein sorting 11 homolog (S. cerevisiae)
chr22_+_38004473 6.11 ENST00000414350.3
ENST00000343632.4
golgi-associated, gamma adaptin ear containing, ARF binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
8.4 33.8 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
6.7 20.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
6.6 19.8 GO:1990108 protein linear deubiquitination(GO:1990108)
4.7 37.8 GO:0007506 gonadal mesoderm development(GO:0007506)
4.4 4.4 GO:0032058 positive regulation of translation in response to stress(GO:0032056) positive regulation of translational initiation in response to stress(GO:0032058)
4.3 39.0 GO:0003190 atrioventricular valve formation(GO:0003190)
4.2 37.9 GO:1903912 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
3.9 11.6 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
3.8 11.5 GO:0042137 sequestering of neurotransmitter(GO:0042137)
3.8 19.1 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
3.8 11.3 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
3.5 10.5 GO:1902534 single-organism membrane invagination(GO:1902534)
3.5 10.4 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
3.4 10.2 GO:0007412 axon target recognition(GO:0007412)
3.1 12.6 GO:1904978 regulation of endosome organization(GO:1904978)
3.1 40.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
2.9 8.8 GO:0018282 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
2.9 2.9 GO:0051084 'de novo' posttranslational protein folding(GO:0051084) chaperone mediated protein folding requiring cofactor(GO:0051085)
2.8 14.0 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
2.8 8.3 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
2.6 7.9 GO:0014807 regulation of somitogenesis(GO:0014807)
2.6 7.9 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
2.6 23.5 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
2.4 12.0 GO:0044026 DNA hypermethylation(GO:0044026)
2.3 6.8 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
2.2 8.8 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
2.1 6.2 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
2.0 6.0 GO:1990502 dense core granule maturation(GO:1990502)
1.9 7.7 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
1.9 5.7 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
1.9 11.3 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
1.8 5.5 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
1.8 23.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
1.7 21.0 GO:1905146 lysosomal protein catabolic process(GO:1905146)
1.7 8.7 GO:2001074 regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
1.7 5.2 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
1.6 11.1 GO:1900107 regulation of nodal signaling pathway(GO:1900107)
1.6 7.8 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
1.5 3.0 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
1.5 4.5 GO:1903465 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
1.5 7.4 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
1.5 4.4 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
1.4 17.1 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
1.4 5.7 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
1.4 8.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
1.4 4.1 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
1.3 9.2 GO:0006477 protein sulfation(GO:0006477)
1.3 10.4 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
1.3 3.8 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
1.3 10.2 GO:0015693 magnesium ion transport(GO:0015693)
1.3 3.8 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
1.2 18.5 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
1.2 8.5 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
1.2 8.4 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
1.2 7.1 GO:0001714 endodermal cell fate specification(GO:0001714)
1.1 3.4 GO:0032286 central nervous system myelin maintenance(GO:0032286)
1.1 9.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
1.1 4.5 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
1.1 16.8 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
1.1 4.4 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
1.1 14.3 GO:0035372 protein localization to microtubule(GO:0035372)
1.1 5.3 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430) growth plate cartilage chondrocyte development(GO:0003431) Harderian gland development(GO:0070384)
1.0 4.2 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
1.0 4.2 GO:0019086 late viral transcription(GO:0019086)
1.0 6.2 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
1.0 7.1 GO:0006102 isocitrate metabolic process(GO:0006102)
1.0 3.9 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
1.0 2.0 GO:0070459 prolactin secretion(GO:0070459)
1.0 10.7 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
1.0 6.8 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
1.0 7.6 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.9 7.3 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.9 6.4 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
0.9 4.6 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.9 10.9 GO:0046548 retinal rod cell development(GO:0046548)
0.9 19.6 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.9 2.7 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.9 13.1 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.9 2.6 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.9 6.8 GO:0008343 adult feeding behavior(GO:0008343)
0.9 14.5 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.8 2.5 GO:1903348 cellular response to lead ion(GO:0071284) positive regulation of bicellular tight junction assembly(GO:1903348)
0.8 6.6 GO:0007288 sperm axoneme assembly(GO:0007288)
0.8 9.1 GO:0021978 telencephalon regionalization(GO:0021978)
0.8 4.9 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.8 3.2 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.8 45.2 GO:0015701 bicarbonate transport(GO:0015701)
0.8 3.9 GO:1900020 embryonic genitalia morphogenesis(GO:0030538) regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.8 2.3 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.8 6.2 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.8 16.0 GO:0070977 bone maturation(GO:0070977)
0.7 2.9 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.7 2.9 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.7 12.3 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.7 2.9 GO:0042335 cuticle development(GO:0042335)
0.7 12.9 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.7 5.0 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.7 28.2 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.7 8.4 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.7 2.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.7 12.9 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.7 5.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.7 7.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.7 4.6 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.7 10.5 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.6 3.2 GO:0019323 pentose catabolic process(GO:0019323)
0.6 11.5 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.6 4.5 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.6 3.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.6 1.9 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.6 7.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.6 1.8 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.6 6.1 GO:0006600 creatine metabolic process(GO:0006600)
0.6 23.0 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.6 1.2 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.6 4.7 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.6 4.7 GO:0007000 nucleolus organization(GO:0007000)
0.6 6.4 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.6 2.9 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.6 7.2 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.5 3.8 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.5 1.1 GO:1904779 regulation of protein localization to centrosome(GO:1904779)
0.5 1.6 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.5 1.1 GO:0061526 acetylcholine secretion(GO:0061526)
0.5 1.6 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.5 5.8 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.5 1.0 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.5 6.1 GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.5 4.1 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.5 2.0 GO:0010587 miRNA catabolic process(GO:0010587)
0.5 0.5 GO:0030514 regulation of BMP signaling pathway(GO:0030510) negative regulation of BMP signaling pathway(GO:0030514)
0.5 2.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.5 2.5 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.5 6.0 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.5 3.5 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.5 10.9 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.5 2.0 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.5 4.9 GO:0016198 axon choice point recognition(GO:0016198)
0.5 1.4 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.5 2.4 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.5 7.1 GO:0021756 striatum development(GO:0021756)
0.5 3.2 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.5 1.8 GO:0033076 alkaloid catabolic process(GO:0009822) isoquinoline alkaloid metabolic process(GO:0033076) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.4 2.2 GO:0002218 activation of innate immune response(GO:0002218) innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223) innate immune response-activating signal transduction(GO:0002758)
0.4 8.3 GO:0031167 rRNA methylation(GO:0031167)
0.4 7.4 GO:0031033 myosin filament organization(GO:0031033)
0.4 3.9 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372) response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.4 6.4 GO:0010629 negative regulation of gene expression(GO:0010629)
0.4 2.5 GO:0016559 peroxisome fission(GO:0016559)
0.4 16.3 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.4 9.2 GO:0032402 melanosome transport(GO:0032402)
0.4 5.8 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.4 2.5 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.4 19.0 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.4 3.2 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.4 32.9 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.4 5.8 GO:0021681 cerebellar granular layer development(GO:0021681)
0.4 5.0 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.4 7.6 GO:0006853 carnitine shuttle(GO:0006853)
0.4 1.9 GO:0042631 cellular response to water deprivation(GO:0042631)
0.4 3.4 GO:0051005 plasma membrane to endosome transport(GO:0048227) negative regulation of lipoprotein lipase activity(GO:0051005)
0.4 23.9 GO:0021762 substantia nigra development(GO:0021762)
0.4 9.7 GO:0003299 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.4 3.9 GO:0008298 intracellular mRNA localization(GO:0008298)
0.4 3.9 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.4 6.4 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.3 2.4 GO:0050915 sensory perception of sour taste(GO:0050915)
0.3 6.8 GO:0032098 regulation of appetite(GO:0032098)
0.3 2.0 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.3 1.0 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.3 3.0 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.3 6.6 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.3 11.4 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.3 4.6 GO:0007409 axonogenesis(GO:0007409)
0.3 5.5 GO:0005513 detection of calcium ion(GO:0005513)
0.3 2.6 GO:0070995 NADPH oxidation(GO:0070995)
0.3 2.8 GO:0032226 positive regulation of synaptic transmission, dopaminergic(GO:0032226) positive regulation of cell adhesion molecule production(GO:0060355) positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.3 13.9 GO:1901998 toxin transport(GO:1901998)
0.3 0.9 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) positive regulation of vascular wound healing(GO:0035470) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.3 9.5 GO:0001510 RNA methylation(GO:0001510)
0.3 7.6 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.3 2.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.3 1.2 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.3 9.6 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.3 17.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.3 0.9 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.3 2.0 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.3 1.4 GO:0009957 epidermal cell fate specification(GO:0009957)
0.3 3.1 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.3 3.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.3 3.3 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.3 1.3 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.3 2.6 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.3 1.8 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 1.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.2 5.6 GO:0045109 intermediate filament organization(GO:0045109)
0.2 3.9 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.2 4.5 GO:0006379 mRNA cleavage(GO:0006379)
0.2 12.5 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.2 10.8 GO:0051646 mitochondrion localization(GO:0051646)
0.2 6.7 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.2 0.9 GO:0042428 serotonin metabolic process(GO:0042428)
0.2 2.3 GO:0000186 activation of MAPKK activity(GO:0000186)
0.2 0.7 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2 6.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.2 4.0 GO:0048535 lymph node development(GO:0048535)
0.2 5.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.2 3.0 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 1.3 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.2 5.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.2 1.7 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.2 4.7 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.2 1.9 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 2.1 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.2 3.5 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.2 5.4 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.2 0.4 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.2 0.4 GO:0042713 sperm ejaculation(GO:0042713)
0.2 3.8 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.2 2.4 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.2 6.3 GO:1903146 regulation of mitophagy(GO:1903146)
0.2 3.3 GO:0009452 7-methylguanosine mRNA capping(GO:0006370) 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.2 8.2 GO:0010107 potassium ion import(GO:0010107)
0.2 1.0 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.2 4.0 GO:0030199 collagen fibril organization(GO:0030199)
0.2 1.3 GO:0008585 female gonad development(GO:0008585)
0.2 2.1 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.2 3.2 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.2 1.3 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.2 7.9 GO:0018149 peptide cross-linking(GO:0018149)
0.2 5.3 GO:0009081 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.2 4.2 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.2 3.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.2 2.0 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.2 2.5 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.2 1.3 GO:1902744 negative regulation of lamellipodium assembly(GO:0010593) negative regulation of lamellipodium organization(GO:1902744)
0.2 1.0 GO:0006021 inositol biosynthetic process(GO:0006021)
0.2 10.9 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.2 1.3 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.2 0.6 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.2 5.0 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.2 4.5 GO:0043029 T cell homeostasis(GO:0043029)
0.1 0.6 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 10.0 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 5.1 GO:0060271 cilium morphogenesis(GO:0060271)
0.1 7.1 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.1 1.0 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 0.9 GO:1904646 positive regulation of superoxide anion generation(GO:0032930) cellular response to beta-amyloid(GO:1904646)
0.1 2.1 GO:0098856 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.1 4.1 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.1 1.1 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.1 2.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 3.4 GO:0032456 endocytic recycling(GO:0032456)
0.1 0.4 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.1 0.4 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 3.2 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 11.2 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.1 2.5 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 1.6 GO:0007625 grooming behavior(GO:0007625)
0.1 2.1 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 2.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 6.2 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.1 2.2 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 2.5 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 1.4 GO:0035810 positive regulation of urine volume(GO:0035810)
0.1 2.6 GO:0007398 ectoderm development(GO:0007398)
0.1 3.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 15.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 2.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 2.8 GO:0044803 multi-organism membrane organization(GO:0044803)
0.1 14.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.7 GO:0023014 signal transduction by protein phosphorylation(GO:0023014)
0.1 1.7 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.1 0.4 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 0.9 GO:0015074 DNA integration(GO:0015074)
0.1 0.7 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.7 GO:0050654 chondroitin sulfate metabolic process(GO:0030204) chondroitin sulfate catabolic process(GO:0030207) chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.1 5.5 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 1.7 GO:0070734 peptidyl-lysine dimethylation(GO:0018027) histone H3-K27 methylation(GO:0070734)
0.1 3.4 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.1 1.3 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.1 4.7 GO:0021954 central nervous system neuron development(GO:0021954)
0.1 3.7 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 3.9 GO:0010507 negative regulation of autophagy(GO:0010507)
0.1 0.3 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.1 1.0 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.1 1.8 GO:0007018 microtubule-based movement(GO:0007018)
0.1 1.3 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 3.4 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.1 2.5 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 1.0 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.1 3.1 GO:0030317 sperm motility(GO:0030317)
0.1 1.8 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.4 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 4.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 4.0 GO:0006611 protein export from nucleus(GO:0006611)
0.1 2.9 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.1 1.7 GO:0033344 cholesterol efflux(GO:0033344)
0.1 1.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 0.8 GO:0010761 fibroblast migration(GO:0010761)
0.1 5.6 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 0.3 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.1 1.7 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.1 5.2 GO:0006024 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.1 0.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.6 GO:0032364 oxygen homeostasis(GO:0032364)
0.1 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.8 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.1 0.9 GO:0030252 growth hormone secretion(GO:0030252)
0.1 7.5 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.1 3.5 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.4 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 4.0 GO:0003014 renal system process(GO:0003014)
0.0 0.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
0.0 1.8 GO:0016266 O-glycan processing(GO:0016266)
0.0 1.6 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 2.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 2.9 GO:0009306 protein secretion(GO:0009306)
0.0 0.9 GO:0001895 retina homeostasis(GO:0001895)
0.0 2.5 GO:1901184 regulation of ERBB signaling pathway(GO:1901184)
0.0 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.7 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.9 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 1.7 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.0 1.2 GO:0030279 negative regulation of ossification(GO:0030279)
0.0 1.2 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 2.1 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 1.7 GO:0030282 bone mineralization(GO:0030282)
0.0 1.2 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 0.5 GO:0031648 protein destabilization(GO:0031648)
0.0 1.2 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.5 GO:0030218 erythrocyte differentiation(GO:0030218)
0.0 5.1 GO:0016311 dephosphorylation(GO:0016311)
0.0 2.3 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.3 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.2 GO:0015884 folic acid transport(GO:0015884)
0.0 0.1 GO:0038089 positive regulation of cell migration by vascular endothelial growth factor signaling pathway(GO:0038089)
0.0 0.2 GO:0032418 lysosome localization(GO:0032418)
0.0 0.9 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 1.0 GO:0051291 protein heterooligomerization(GO:0051291)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 32.9 GO:0005672 transcription factor TFIIA complex(GO:0005672)
3.5 10.5 GO:0019034 viral replication complex(GO:0019034)
2.4 7.3 GO:0034657 GID complex(GO:0034657)
2.3 11.3 GO:0071797 LUBAC complex(GO:0071797)
2.1 6.4 GO:0031251 PAN complex(GO:0031251)
2.1 19.0 GO:0005638 lamin filament(GO:0005638)
2.1 35.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
1.7 6.7 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
1.6 4.7 GO:0060187 cell pole(GO:0060187)
1.4 14.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
1.4 11.5 GO:0060203 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
1.3 6.6 GO:0031501 mannosyltransferase complex(GO:0031501)
1.3 5.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
1.3 10.1 GO:0032593 insulin-responsive compartment(GO:0032593)
1.2 2.3 GO:0033648 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
1.2 13.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
1.1 12.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
1.1 9.9 GO:0030897 HOPS complex(GO:0030897)
1.1 5.5 GO:0005594 collagen type IX trimer(GO:0005594)
1.1 5.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.0 5.8 GO:1990769 proximal neuron projection(GO:1990769)
1.0 10.5 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.9 8.4 GO:0034464 BBSome(GO:0034464)
0.9 6.5 GO:0044326 dendritic spine neck(GO:0044326)
0.9 7.2 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.9 21.0 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.9 11.3 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.8 8.5 GO:0045180 basal cortex(GO:0045180)
0.8 3.3 GO:1990031 pinceau fiber(GO:1990031)
0.8 18.2 GO:0044295 axonal growth cone(GO:0044295)
0.8 8.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.7 9.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.7 4.1 GO:0002177 manchette(GO:0002177)
0.7 7.4 GO:0016600 flotillin complex(GO:0016600)
0.6 1.8 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.6 2.4 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.6 3.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.6 2.3 GO:0032279 asymmetric synapse(GO:0032279)
0.6 5.5 GO:0097427 microtubule bundle(GO:0097427)
0.5 11.8 GO:0016580 Sin3 complex(GO:0016580)
0.5 6.5 GO:0030057 desmosome(GO:0030057)
0.5 8.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.5 27.1 GO:0030118 clathrin coat(GO:0030118)
0.5 7.7 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.4 12.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.4 5.6 GO:0005916 fascia adherens(GO:0005916)
0.4 3.9 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.4 19.8 GO:0097542 ciliary tip(GO:0097542)
0.4 2.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.4 1.7 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.4 2.5 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.4 4.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.4 2.9 GO:0030870 Mre11 complex(GO:0030870)
0.4 6.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.4 34.2 GO:0042734 presynaptic membrane(GO:0042734)
0.4 30.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.4 3.2 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.4 8.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.4 4.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.4 4.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.3 1.7 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.3 19.3 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3 6.0 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.3 2.0 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.3 2.6 GO:0032009 early phagosome(GO:0032009)
0.3 4.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.3 2.7 GO:0070652 HAUS complex(GO:0070652)
0.3 14.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.3 3.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.3 10.2 GO:1904115 axon cytoplasm(GO:1904115)
0.3 5.0 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.3 9.0 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.2 7.0 GO:0001533 cornified envelope(GO:0001533)
0.2 3.9 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.2 16.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.2 3.1 GO:0000800 lateral element(GO:0000800)
0.2 4.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 3.2 GO:0001741 XY body(GO:0001741)
0.2 3.8 GO:0001891 phagocytic cup(GO:0001891)
0.2 12.8 GO:0005844 polysome(GO:0005844)
0.2 1.0 GO:0044308 axonal spine(GO:0044308)
0.2 0.8 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.2 20.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.2 24.2 GO:0001650 fibrillar center(GO:0001650)
0.2 2.1 GO:0031526 brush border membrane(GO:0031526)
0.2 2.7 GO:0036038 MKS complex(GO:0036038)
0.2 10.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 5.1 GO:0008021 synaptic vesicle(GO:0008021)
0.2 6.0 GO:0005859 muscle myosin complex(GO:0005859)
0.2 6.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2 25.2 GO:0031225 anchored component of membrane(GO:0031225)
0.2 5.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.2 3.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 4.2 GO:0002080 acrosomal membrane(GO:0002080)
0.2 1.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 0.6 GO:0032044 DSIF complex(GO:0032044)
0.1 4.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 2.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 13.0 GO:0005814 centriole(GO:0005814)
0.1 2.4 GO:0005922 connexon complex(GO:0005922)
0.1 6.0 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 7.6 GO:0009986 cell surface(GO:0009986)
0.1 4.1 GO:0032420 stereocilium(GO:0032420)
0.1 1.4 GO:0043194 axon initial segment(GO:0043194)
0.1 6.8 GO:0043195 terminal bouton(GO:0043195)
0.1 3.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 11.6 GO:0005796 Golgi lumen(GO:0005796)
0.1 5.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 8.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 12.1 GO:0032587 ruffle membrane(GO:0032587)
0.1 1.6 GO:0030914 STAGA complex(GO:0030914)
0.1 5.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 5.7 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 1.6 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 1.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 1.0 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 5.7 GO:0043235 receptor complex(GO:0043235)
0.1 25.1 GO:0043025 neuronal cell body(GO:0043025)
0.1 4.7 GO:0015030 Cajal body(GO:0015030)
0.1 2.2 GO:0032040 small-subunit processome(GO:0032040)
0.1 115.7 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 6.3 GO:0005875 microtubule associated complex(GO:0005875)
0.1 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.7 GO:0098793 presynapse(GO:0098793)
0.1 3.4 GO:0031901 early endosome membrane(GO:0031901)
0.0 2.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.4 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 2.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.3 GO:0035976 AP1 complex(GO:0035976)
0.0 3.3 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 2.5 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.3 GO:0031082 BLOC complex(GO:0031082)
0.0 3.7 GO:0072562 blood microparticle(GO:0072562)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 4.6 GO:0030016 myofibril(GO:0030016)
0.0 47.7 GO:0016021 integral component of membrane(GO:0016021)
0.0 1.0 GO:0000786 nucleosome(GO:0000786)
0.0 0.9 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.7 GO:1904724 tertiary granule lumen(GO:1904724)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
6.7 20.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
5.1 15.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
4.3 17.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
3.9 11.6 GO:0005137 interleukin-5 receptor binding(GO:0005137)
3.8 19.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
3.5 10.4 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
3.4 16.8 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
3.1 12.6 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
3.1 12.5 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
2.9 11.5 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
2.9 8.6 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
2.9 28.6 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
2.8 8.5 GO:0034584 piRNA binding(GO:0034584)
2.8 14.0 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
2.8 8.3 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
2.7 16.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
2.6 10.2 GO:0052812 phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
2.5 10.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
2.5 45.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
2.5 12.4 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
2.4 7.1 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
2.3 13.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
1.9 5.7 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
1.9 3.8 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
1.8 10.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
1.7 5.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
1.7 13.8 GO:0004111 creatine kinase activity(GO:0004111)
1.7 3.4 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
1.7 3.4 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
1.7 16.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
1.6 6.6 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
1.6 7.9 GO:0004668 protein-arginine deiminase activity(GO:0004668)
1.6 7.8 GO:0004994 somatostatin receptor activity(GO:0004994)
1.5 10.7 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
1.5 10.4 GO:0017002 activin-activated receptor activity(GO:0017002)
1.5 7.3 GO:0001594 trace-amine receptor activity(GO:0001594)
1.3 6.6 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
1.3 4.0 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
1.3 15.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
1.3 33.1 GO:0031489 myosin V binding(GO:0031489)
1.2 5.0 GO:0031685 adenosine receptor binding(GO:0031685)
1.2 7.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
1.2 6.0 GO:0070097 delta-catenin binding(GO:0070097)
1.2 5.9 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
1.1 4.6 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
1.1 3.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
1.1 6.4 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
1.1 3.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) steroid delta-isomerase activity(GO:0004769)
1.0 16.6 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
1.0 8.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
1.0 4.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
1.0 11.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.9 9.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.9 37.9 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.9 10.5 GO:0048185 activin binding(GO:0048185)
0.8 7.6 GO:0043426 MRF binding(GO:0043426)
0.8 4.9 GO:0034511 U3 snoRNA binding(GO:0034511)
0.8 4.0 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.8 5.5 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.8 4.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.8 16.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.7 10.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.7 4.4 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.7 10.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.7 10.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.7 7.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.7 2.9 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.7 4.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.7 2.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.7 4.7 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.6 14.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.6 3.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.6 2.3 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.6 10.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.6 1.7 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.6 3.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.6 8.8 GO:0016783 sulfurtransferase activity(GO:0016783)
0.5 2.7 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.5 14.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.5 3.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.5 3.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.5 4.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.5 10.9 GO:0015929 hexosaminidase activity(GO:0015929)
0.5 6.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.5 3.0 GO:0039552 RIG-I binding(GO:0039552)
0.5 12.0 GO:0002162 dystroglycan binding(GO:0002162)
0.5 2.4 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.5 13.3 GO:0005521 lamin binding(GO:0005521)
0.5 2.4 GO:0086077 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.5 7.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.5 2.3 GO:0070905 serine binding(GO:0070905)
0.5 6.0 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.5 7.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.5 4.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.4 7.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.4 6.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.4 2.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.4 4.7 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.4 3.4 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.4 10.9 GO:0004806 triglyceride lipase activity(GO:0004806)
0.4 8.4 GO:0034979 NAD-dependent protein deacetylase activity(GO:0034979)
0.4 2.5 GO:0017018 myosin phosphatase activity(GO:0017018)
0.4 13.8 GO:0008066 glutamate receptor activity(GO:0008066)
0.4 6.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.4 8.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.4 3.2 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.4 6.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.4 18.8 GO:0042169 SH2 domain binding(GO:0042169)
0.4 36.3 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.4 1.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.4 2.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.4 1.8 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.4 2.9 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.4 2.5 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.4 6.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.4 5.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.3 6.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.3 1.7 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.3 2.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.3 1.6 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.3 7.1 GO:0035198 miRNA binding(GO:0035198)
0.3 6.4 GO:0035497 cAMP response element binding(GO:0035497)
0.3 3.8 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.3 9.9 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.3 24.1 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.3 1.3 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.3 4.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.3 8.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.3 11.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.3 8.1 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.3 1.8 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.3 3.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.3 11.2 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.3 5.1 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.3 2.8 GO:0042608 T cell receptor binding(GO:0042608)
0.3 6.6 GO:0030371 translation repressor activity(GO:0030371)
0.3 0.3 GO:0034056 estrogen response element binding(GO:0034056)
0.3 1.9 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.3 4.1 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.3 3.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.3 6.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.3 3.7 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.3 1.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.3 4.4 GO:0043022 ribosome binding(GO:0043022)
0.3 2.6 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.3 5.1 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.2 3.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.2 1.0 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.2 9.5 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.2 0.9 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.2 0.9 GO:0005124 scavenger receptor binding(GO:0005124)
0.2 1.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 3.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 2.9 GO:0070700 BMP receptor binding(GO:0070700)
0.2 0.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.2 5.4 GO:0030506 ankyrin binding(GO:0030506)
0.2 4.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.2 10.9 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.2 5.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 10.0 GO:0030507 spectrin binding(GO:0030507)
0.2 9.2 GO:0008146 sulfotransferase activity(GO:0008146)
0.2 3.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.2 5.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.2 7.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 22.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 2.9 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.2 1.0 GO:0097016 L27 domain binding(GO:0097016)
0.2 3.9 GO:0031005 filamin binding(GO:0031005)
0.2 3.5 GO:0050780 dopamine receptor binding(GO:0050780)
0.2 2.6 GO:0035325 Toll-like receptor binding(GO:0035325)
0.2 7.7 GO:0030551 cyclic nucleotide binding(GO:0030551)
0.2 3.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 28.5 GO:0044325 ion channel binding(GO:0044325)
0.2 2.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.2 2.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 3.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 4.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 15.3 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.2 3.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.2 1.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 6.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 0.6 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.1 2.7 GO:0019894 kinesin binding(GO:0019894)
0.1 1.3 GO:0004969 histamine receptor activity(GO:0004969)
0.1 8.2 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 3.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.7 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.8 GO:0031432 titin binding(GO:0031432)
0.1 8.6 GO:0002039 p53 binding(GO:0002039)
0.1 2.5 GO:0005112 Notch binding(GO:0005112)
0.1 0.4 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 5.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 2.8 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 1.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 6.1 GO:0019903 protein phosphatase binding(GO:0019903)
0.1 1.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 21.9 GO:0001047 core promoter binding(GO:0001047)
0.1 0.9 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 1.9 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.1 2.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 5.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 5.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.1 GO:0031419 cobalamin binding(GO:0031419)
0.1 3.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 6.2 GO:0030276 clathrin binding(GO:0030276)
0.1 2.9 GO:0070412 R-SMAD binding(GO:0070412)
0.1 24.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 2.3 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 2.8 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 0.4 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 10.4 GO:0046906 heme binding(GO:0020037) tetrapyrrole binding(GO:0046906)
0.1 4.6 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.6 GO:0045545 syndecan binding(GO:0045545)
0.1 2.3 GO:0005158 insulin receptor binding(GO:0005158)
0.1 3.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.1 2.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 1.2 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.4 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 1.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 10.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 4.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 2.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.7 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.4 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 2.5 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 6.5 GO:0008017 microtubule binding(GO:0008017)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 1.3 GO:0004540 ribonuclease activity(GO:0004540)
0.0 1.1 GO:0005230 extracellular ligand-gated ion channel activity(GO:0005230)
0.0 7.1 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542)
0.0 0.8 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.1 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 42.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.9 15.8 PID S1P S1P4 PATHWAY S1P4 pathway
0.8 18.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.7 12.9 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.6 49.9 PID TNF PATHWAY TNF receptor signaling pathway
0.5 6.7 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.5 13.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.5 22.1 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.5 11.1 PID IL5 PATHWAY IL5-mediated signaling events
0.4 7.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.4 12.2 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.4 6.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.3 11.2 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.3 16.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.3 13.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.3 7.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.3 3.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.3 11.6 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.3 15.3 PID FGF PATHWAY FGF signaling pathway
0.3 5.8 PID NECTIN PATHWAY Nectin adhesion pathway
0.2 8.7 PID ALK1 PATHWAY ALK1 signaling events
0.2 5.8 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.2 10.2 PID EPHB FWD PATHWAY EPHB forward signaling
0.2 10.2 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.2 18.1 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.2 14.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.2 4.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.2 5.8 PID FAS PATHWAY FAS (CD95) signaling pathway
0.2 7.1 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.2 7.5 PID SHP2 PATHWAY SHP2 signaling
0.2 4.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 5.9 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 2.8 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 5.0 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 9.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 7.9 PID NOTCH PATHWAY Notch signaling pathway
0.1 3.8 PID RAS PATHWAY Regulation of Ras family activation
0.1 2.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 19.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 0.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 2.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 3.2 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 3.2 PID ENDOTHELIN PATHWAY Endothelins
0.1 8.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 3.4 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 2.1 PID RHOA PATHWAY RhoA signaling pathway
0.1 2.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.6 PID MYC PATHWAY C-MYC pathway
0.1 1.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 3.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 2.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 28.9 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
1.2 16.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
1.2 2.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
1.0 18.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.9 4.5 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.9 11.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.8 11.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.8 26.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.6 10.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.6 5.5 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.5 4.4 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.5 10.6 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.5 10.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.5 7.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.5 8.8 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.5 30.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.5 5.0 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.5 10.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.5 21.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.5 14.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.5 10.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.5 6.0 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.5 2.7 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.5 9.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.4 52.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.4 11.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.4 13.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.4 33.1 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.4 25.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.4 11.4 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.3 4.8 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.3 4.4 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.3 6.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.3 16.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.3 5.0 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.3 10.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.3 2.9 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.3 6.8 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.2 6.0 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 5.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 10.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.2 10.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.2 3.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.2 6.1 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.2 2.6 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.2 2.6 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.2 9.9 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.2 6.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 3.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 5.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 16.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 5.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.2 4.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 2.4 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.2 2.5 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 3.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 2.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 2.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 4.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 6.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.4 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 9.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 1.1 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 3.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 2.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 5.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 27.4 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.1 2.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.6 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 9.3 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.1 1.7 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 7.0 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 1.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 4.2 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.1 1.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 1.6 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 2.5 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.1 13.1 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 0.5 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 3.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.8 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 1.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.2 REACTOME BILE ACID AND BILE SALT METABOLISM Genes involved in Bile acid and bile salt metabolism
0.0 2.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors