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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ZFX

Z-value: 2.45

Motif logo

Transcription factors associated with ZFX

Gene Symbol Gene ID Gene Info
ENSG00000005889.11 zinc finger protein X-linked

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZFXhg19_v2_chrX_+_24167828_24167907-0.714.0e-34Click!

Activity profile of ZFX motif

Sorted Z-values of ZFX motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_103748271 44.69 ENST00000343106.5
ubiquitin-conjugating enzyme E2D 3
chr20_+_47662805 44.32 ENST00000262982.2
ENST00000542325.1
CSE1 chromosome segregation 1-like (yeast)
chr16_+_67063036 43.68 ENST00000290858.6
ENST00000564034.1
core-binding factor, beta subunit
chr16_+_67063142 41.72 ENST00000412916.2
core-binding factor, beta subunit
chr4_-_103748696 39.26 ENST00000321805.7
ubiquitin-conjugating enzyme E2D 3
chr8_-_54935001 39.21 ENST00000396401.3
ENST00000521604.2
transcription elongation factor A (SII), 1
chr15_-_49447771 34.87 ENST00000558843.1
ENST00000542928.1
ENST00000561248.1
COP9 signalosome subunit 2
chr18_+_158513 33.73 ENST00000400266.3
ENST00000580410.1
ENST00000383589.2
ENST00000261601.7
ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
chr4_-_174255536 33.20 ENST00000446922.2
high mobility group box 2
chr11_-_73693875 32.98 ENST00000536983.1
uncoupling protein 2 (mitochondrial, proton carrier)
chr14_+_58711539 32.82 ENST00000216455.4
ENST00000412908.2
ENST00000557508.1
proteasome (prosome, macropain) subunit, alpha type, 3
chr11_-_64013288 32.73 ENST00000542235.1
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr11_-_46142948 32.66 ENST00000257821.4
PHD finger protein 21A
chr20_-_32891151 32.51 ENST00000217426.2
adenosylhomocysteinase
chr4_-_71705060 32.29 ENST00000514161.1
G-rich RNA sequence binding factor 1
chr14_-_69864993 31.42 ENST00000555373.1
enhancer of rudimentary homolog (Drosophila)
chr19_+_1065922 31.31 ENST00000539243.2
histocompatibility (minor) HA-1
chr14_+_56046990 31.15 ENST00000438792.2
ENST00000395314.3
ENST00000395308.1
kinectin 1 (kinesin receptor)
chr15_-_59225758 31.14 ENST00000558486.1
ENST00000560682.1
ENST00000249736.7
ENST00000559880.1
ENST00000536328.1
SAFB-like, transcription modulator
chr17_+_45608430 31.08 ENST00000322157.4
aminopeptidase puromycin sensitive
chr19_-_55919087 30.90 ENST00000587845.1
ENST00000589978.1
ENST00000264552.9
ubiquitin-conjugating enzyme E2S
chr5_+_177631523 29.91 ENST00000506339.1
ENST00000355836.5
ENST00000514633.1
ENST00000515193.1
ENST00000506259.1
ENST00000504898.1
heterogeneous nuclear ribonucleoprotein A/B
chr16_-_29466285 29.86 ENST00000330978.3
bolA family member 2
chr6_-_17706618 29.59 ENST00000262077.2
ENST00000537253.1
nucleoporin 153kDa
chr7_+_148395959 28.89 ENST00000325222.4
cullin 1
chr12_-_57081940 28.88 ENST00000436399.2
prostaglandin E synthase 3 (cytosolic)
chr19_+_54695098 28.88 ENST00000396388.2
TSEN34 tRNA splicing endonuclease subunit
chr5_+_72112470 28.54 ENST00000447967.2
ENST00000523768.1
transportin 1
chr16_-_50402836 28.05 ENST00000394688.3
bromodomain containing 7
chr2_-_64881018 27.30 ENST00000313349.3
SERTA domain containing 2
chr16_-_50402690 27.22 ENST00000394689.2
bromodomain containing 7
chr10_+_22610124 26.98 ENST00000376663.3
BMI1 polycomb ring finger oncogene
chr8_-_27695552 26.88 ENST00000522944.1
ENST00000301905.4
PDZ binding kinase
chr14_+_56046914 26.78 ENST00000413890.2
ENST00000395309.3
ENST00000554567.1
ENST00000555498.1
kinectin 1 (kinesin receptor)
chr19_+_8509842 26.69 ENST00000325495.4
ENST00000600092.1
ENST00000594907.1
ENST00000596984.1
ENST00000601645.1
heterogeneous nuclear ribonucleoprotein M
chr5_+_177631497 26.64 ENST00000358344.3
heterogeneous nuclear ribonucleoprotein A/B
chr7_+_98972345 26.49 ENST00000418347.2
ENST00000429246.1
ENST00000417330.1
ENST00000431816.1
ENST00000427217.1
ENST00000458033.1
ENST00000451682.1
actin related protein 2/3 complex, subunit 1B, 41kDa
chr7_+_5085452 26.39 ENST00000353796.3
ENST00000396912.1
ENST00000396904.2
RB-associated KRAB zinc finger
RBAK-RBAKDN readthrough
chr7_+_73588575 26.16 ENST00000265753.8
eukaryotic translation initiation factor 4H
chrX_+_131157322 25.67 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
Serine/threonine-protein kinase MST4
chr4_-_71705027 25.63 ENST00000545193.1
G-rich RNA sequence binding factor 1
chrX_+_131157290 25.51 ENST00000394334.2
Serine/threonine-protein kinase MST4
chr15_+_77224045 25.50 ENST00000320963.5
ENST00000394883.3
reticulocalbin 2, EF-hand calcium binding domain
chr16_+_29817841 25.28 ENST00000322945.6
ENST00000562337.1
ENST00000566906.2
ENST00000563402.1
ENST00000219782.6
MYC-associated zinc finger protein (purine-binding transcription factor)
chr3_-_69129501 25.22 ENST00000540295.1
ENST00000415609.2
ENST00000361055.4
ENST00000349511.4
ubiquitin-like modifier activating enzyme 3
chr9_+_131451480 25.19 ENST00000322030.8
SET nuclear oncogene
chr20_-_61847586 25.00 ENST00000370339.3
YTH domain family, member 1
chr8_+_98656336 24.96 ENST00000336273.3
metadherin
chr17_-_36413133 24.92 ENST00000523089.1
ENST00000312412.4
ENST00000520237.1
TBC1 domain family member 3
chr14_+_53173910 24.77 ENST00000606149.1
ENST00000555339.1
ENST00000556813.1
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr7_+_98972298 24.55 ENST00000252725.5
actin related protein 2/3 complex, subunit 1B, 41kDa
chr6_+_116892530 24.30 ENST00000466444.2
ENST00000368590.5
ENST00000392526.1
RWD domain containing 1
chr17_-_73150599 24.23 ENST00000392566.2
ENST00000581874.1
hematological and neurological expressed 1
chr2_+_48010312 24.16 ENST00000540021.1
mutS homolog 6
chr14_+_53173890 24.12 ENST00000445930.2
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr18_-_54305658 24.09 ENST00000586262.1
ENST00000217515.6
thioredoxin-like 1
chr2_+_48010221 23.80 ENST00000234420.5
mutS homolog 6
chr18_+_29672573 23.80 ENST00000578107.1
ENST00000257190.5
ENST00000580499.1
ring finger protein 138, E3 ubiquitin protein ligase
chr7_+_2394445 23.57 ENST00000360876.4
ENST00000413917.1
ENST00000397011.2
eukaryotic translation initiation factor 3, subunit B
chr19_+_33865218 23.48 ENST00000585933.2
CCAAT/enhancer binding protein (C/EBP), gamma
chr1_-_6453426 23.27 ENST00000545482.1
acyl-CoA thioesterase 7
chr17_+_1733276 23.13 ENST00000254719.5
replication protein A1, 70kDa
chr9_-_139760717 22.82 ENST00000371648.4
endothelial differentiation-related factor 1
chr1_+_112162381 22.82 ENST00000433097.1
ENST00000369709.3
ENST00000436150.2
RAP1A, member of RAS oncogene family
chr8_+_98656693 22.62 ENST00000519934.1
metadherin
chr2_+_85198216 22.36 ENST00000456682.1
ENST00000409785.4
potassium channel modulatory factor 1
chr6_+_116892641 22.26 ENST00000487832.2
ENST00000518117.1
RWD domain containing 1
chr16_-_85833109 22.22 ENST00000253457.3
ER membrane protein complex subunit 8
chrX_+_146993449 22.11 ENST00000218200.8
ENST00000370471.3
ENST00000370477.1
fragile X mental retardation 1
chr10_-_88281494 21.94 ENST00000298767.5
wings apart-like homolog (Drosophila)
chr12_-_120907374 21.91 ENST00000550458.1
serine/arginine-rich splicing factor 9
chr15_-_59225844 21.84 ENST00000380516.2
SAFB-like, transcription modulator
chr4_-_183838596 21.78 ENST00000508994.1
ENST00000512766.1
dCMP deaminase
chr16_-_85833160 21.73 ENST00000435200.2
ER membrane protein complex subunit 8
chr11_-_46142615 21.70 ENST00000529734.1
ENST00000323180.6
PHD finger protein 21A
chr11_-_67169253 21.60 ENST00000527663.1
ENST00000312989.7
protein phosphatase 1, catalytic subunit, alpha isozyme
chr2_+_114647504 21.57 ENST00000263238.2
ARP3 actin-related protein 3 homolog (yeast)
chr2_-_10588630 21.53 ENST00000234111.4
ornithine decarboxylase 1
chrX_-_16887963 21.39 ENST00000380084.4
retinoblastoma binding protein 7
chr1_-_53704157 21.35 ENST00000371466.4
ENST00000371470.3
mago-nashi homolog, proliferation-associated (Drosophila)
chr10_+_51565108 21.29 ENST00000438493.1
ENST00000452682.1
nuclear receptor coactivator 4
chr3_-_53290016 21.27 ENST00000423525.2
ENST00000423516.1
ENST00000296289.6
ENST00000462138.1
transketolase
chr2_-_175113088 21.20 ENST00000409546.1
ENST00000428402.2
Obg-like ATPase 1
chr11_+_1968508 20.95 ENST00000397298.3
ENST00000381519.1
ENST00000397297.3
ENST00000381514.3
ENST00000397294.3
mitochondrial ribosomal protein L23
chr7_+_98476095 20.89 ENST00000359863.4
ENST00000355540.3
transformation/transcription domain-associated protein
chr19_+_1067271 20.89 ENST00000536472.1
ENST00000590214.1
histocompatibility (minor) HA-1
chr3_+_23847432 20.88 ENST00000346855.3
ubiquitin-conjugating enzyme E2E 1
chr8_-_63951730 20.72 ENST00000260118.6
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
chr7_-_96339132 20.58 ENST00000413065.1
split hand/foot malformation (ectrodactyly) type 1
chr12_+_121837844 20.46 ENST00000361234.5
ring finger protein 34, E3 ubiquitin protein ligase
chr1_+_43148625 20.43 ENST00000436427.1
Y box binding protein 1
chr12_+_122241928 20.15 ENST00000604567.1
ENST00000542440.1
SET domain containing 1B
chr15_+_77223960 20.03 ENST00000394885.3
reticulocalbin 2, EF-hand calcium binding domain
chr17_-_73149921 19.92 ENST00000481647.1
ENST00000470924.1
hematological and neurological expressed 1
chr4_-_103748880 19.91 ENST00000453744.2
ENST00000349311.8
ubiquitin-conjugating enzyme E2D 3
chr10_+_88854926 19.65 ENST00000298784.1
ENST00000298786.4
family with sequence similarity 35, member A
chr10_-_120840309 19.63 ENST00000369144.3
eukaryotic translation initiation factor 3, subunit A
chr3_+_52740094 19.59 ENST00000602728.1
signal peptidase complex subunit 1 homolog (S. cerevisiae)
chr3_+_140660743 19.45 ENST00000453248.2
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36
chr10_+_51565188 19.40 ENST00000430396.2
ENST00000374087.4
ENST00000414907.2
nuclear receptor coactivator 4
chr19_+_36036477 19.32 ENST00000222284.5
ENST00000392204.2
transmembrane protein 147
chr15_-_49447835 19.27 ENST00000388901.5
ENST00000299259.6
COP9 signalosome subunit 2
chr19_-_8070474 19.13 ENST00000407627.2
ENST00000593807.1
ELAV like RNA binding protein 1
chr22_-_19165917 19.10 ENST00000451283.1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr17_-_73150629 19.09 ENST00000356033.4
ENST00000405458.3
ENST00000409753.3
hematological and neurological expressed 1
chr19_-_10464570 19.03 ENST00000529739.1
tyrosine kinase 2
chr1_-_19811132 19.00 ENST00000433834.1
capping protein (actin filament) muscle Z-line, beta
chr2_-_85645545 18.96 ENST00000409275.1
capping protein (actin filament), gelsolin-like
chr2_+_102314161 18.62 ENST00000425019.1
mitogen-activated protein kinase kinase kinase kinase 4
chr19_+_59055814 18.62 ENST00000594806.1
ENST00000253024.5
ENST00000341753.6
tripartite motif containing 28
chr2_-_74735707 18.45 ENST00000233630.6
polycomb group ring finger 1
chrX_+_150151752 18.31 ENST00000325307.7
high mobility group box 3
chr19_+_1067144 18.24 ENST00000313093.2
histocompatibility (minor) HA-1
chr19_-_48894104 18.18 ENST00000597017.1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr12_-_76478417 18.16 ENST00000552342.1
nucleosome assembly protein 1-like 1
chr2_-_175113301 18.12 ENST00000344357.5
ENST00000284719.3
Obg-like ATPase 1
chr15_+_78833071 18.03 ENST00000559365.1
proteasome (prosome, macropain) subunit, alpha type, 4
chr3_+_52719936 17.96 ENST00000418458.1
ENST00000394799.2
guanine nucleotide binding protein-like 3 (nucleolar)
chr16_-_58768177 17.88 ENST00000434819.2
ENST00000245206.5
glutamic-oxaloacetic transaminase 2, mitochondrial
chr2_-_61697862 17.84 ENST00000398571.2
ubiquitin specific peptidase 34
chr9_+_131452239 17.82 ENST00000372688.4
ENST00000372686.5
SET nuclear oncogene
chrX_+_154611749 17.78 ENST00000369505.3
coagulation factor VIII-associated 2
chr16_+_69345243 17.72 ENST00000254950.11
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr19_-_15443318 17.72 ENST00000360016.5
bromodomain containing 4
chr17_+_66509019 17.67 ENST00000585981.1
ENST00000589480.1
ENST00000585815.1
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr19_+_36036583 17.65 ENST00000392205.1
transmembrane protein 147
chr14_-_105262055 17.61 ENST00000349310.3
v-akt murine thymoma viral oncogene homolog 1
chr4_+_110354928 17.56 ENST00000504968.2
ENST00000399100.2
ENST00000265175.5
SEC24 family member B
chr18_+_9102592 17.51 ENST00000318388.6
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
chr20_+_32581452 17.50 ENST00000375114.3
ENST00000448364.1
RALY heterogeneous nuclear ribonucleoprotein
chr1_+_203830703 17.48 ENST00000414487.2
small nuclear ribonucleoprotein polypeptide E
chr4_+_140222609 17.44 ENST00000296543.5
ENST00000398947.1
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr15_+_40453204 17.34 ENST00000287598.6
ENST00000412359.3
BUB1 mitotic checkpoint serine/threonine kinase B
chr5_+_179125907 17.33 ENST00000247461.4
ENST00000452673.2
ENST00000502498.1
ENST00000507307.1
ENST00000513246.1
ENST00000502673.1
ENST00000506654.1
ENST00000512607.2
ENST00000510810.1
calnexin
chr17_+_45608614 17.23 ENST00000544660.1
aminopeptidase puromycin sensitive
chr10_-_126847276 17.18 ENST00000531469.1
C-terminal binding protein 2
chr1_-_6453399 17.14 ENST00000608083.1
acyl-CoA thioesterase 7
chr1_+_41445413 17.12 ENST00000541520.1
CTP synthase 1
chr7_-_32534850 17.11 ENST00000409952.3
ENST00000409909.3
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr12_+_121837905 17.06 ENST00000392465.3
ENST00000554606.1
ENST00000392464.2
ENST00000555076.1
ring finger protein 34, E3 ubiquitin protein ligase
chr5_+_162864575 17.02 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
cyclin G1
chr17_-_40075197 17.00 ENST00000590770.1
ENST00000590151.1
ATP citrate lyase
chr17_-_20946338 16.91 ENST00000261497.4
ubiquitin specific peptidase 22
chr9_-_74979420 16.89 ENST00000343431.2
ENST00000376956.3
zinc finger, AN1-type domain 5
chr19_+_572543 16.88 ENST00000333511.3
ENST00000573216.1
ENST00000353555.4
basigin (Ok blood group)
chr15_+_78833105 16.86 ENST00000558341.1
ENST00000559437.1
proteasome (prosome, macropain) subunit, alpha type, 4
chr14_-_105262016 16.63 ENST00000407796.2
v-akt murine thymoma viral oncogene homolog 1
chr17_+_40761660 16.62 ENST00000251413.3
ENST00000591509.1
tubulin, gamma 1
chr9_-_139760737 16.60 ENST00000371649.1
ENST00000224073.1
endothelial differentiation-related factor 1
chr5_-_77072145 16.51 ENST00000380377.4
tubulin folding cofactor A
chr15_+_41624892 16.47 ENST00000260359.6
ENST00000450318.1
ENST00000450592.2
ENST00000559596.1
ENST00000414849.2
ENST00000560747.1
ENST00000560177.1
nucleolar and spindle associated protein 1
chr3_+_183894566 16.47 ENST00000439647.1
adaptor-related protein complex 2, mu 1 subunit
chr11_-_3862206 16.45 ENST00000351018.4
ras homolog family member G
chr11_+_67374323 16.43 ENST00000322776.6
ENST00000532303.1
ENST00000532244.1
ENST00000528328.1
ENST00000529927.1
ENST00000532343.1
ENST00000415352.2
ENST00000533075.1
ENST00000529867.1
ENST00000530638.1
NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
chr1_-_11120057 16.43 ENST00000376957.2
spermidine synthase
chr5_+_139781393 16.43 ENST00000360839.2
ENST00000297183.6
ENST00000421134.1
ENST00000394723.3
ENST00000511151.1
ankyrin repeat and KH domain containing 1
chr4_-_140223670 16.42 ENST00000394228.1
ENST00000539387.1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr14_+_52456327 16.39 ENST00000556760.1
chromosome 14 open reading frame 166
chr5_+_134094461 16.36 ENST00000452510.2
ENST00000354283.4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
chr11_-_73687997 16.36 ENST00000545212.1
uncoupling protein 2 (mitochondrial, proton carrier)
chr12_+_104324112 16.35 ENST00000299767.5
heat shock protein 90kDa beta (Grp94), member 1
chr2_+_201676908 16.35 ENST00000409226.1
ENST00000452790.2
basic leucine zipper and W2 domains 1
chr7_+_73588665 16.35 ENST00000353999.6
eukaryotic translation initiation factor 4H
chr16_-_87903079 16.32 ENST00000261622.4
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chrX_+_40440146 16.30 ENST00000535539.1
ENST00000378438.4
ENST00000436783.1
ENST00000544975.1
ENST00000535777.1
ENST00000447485.1
ENST00000423649.1
ATPase, H+ transporting, lysosomal accessory protein 2
chr8_-_102216925 16.25 ENST00000517844.1
zinc finger protein 706
chr12_-_57082060 16.24 ENST00000448157.2
ENST00000414274.3
ENST00000262033.6
ENST00000456859.2
prostaglandin E synthase 3 (cytosolic)
chr1_+_100731749 16.14 ENST00000370128.4
ENST00000260563.4
RNA 3'-terminal phosphate cyclase
chr12_+_56110374 16.12 ENST00000549424.1
Uncharacterized protein
chr11_+_747329 16.03 ENST00000319006.3
ENST00000528097.1
transaldolase 1
chr20_+_56964253 16.00 ENST00000395802.3
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr1_-_153522562 15.97 ENST00000368714.1
S100 calcium binding protein A4
chr16_-_67694129 15.95 ENST00000602320.1
adrenocortical dysplasia homolog (mouse)
chr3_-_129035120 15.92 ENST00000333762.4
H1 histone family, member X
chr16_-_46723066 15.89 ENST00000299138.7
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr15_+_78832747 15.84 ENST00000560217.1
ENST00000044462.7
ENST00000559082.1
ENST00000559948.1
ENST00000413382.2
ENST00000559146.1
ENST00000558281.1
proteasome (prosome, macropain) subunit, alpha type, 4
chr1_-_94374946 15.83 ENST00000370238.3
glutamate-cysteine ligase, modifier subunit
chr16_-_11891048 15.82 ENST00000571198.1
ENST00000572781.1
ENST00000355758.4
zinc finger CCCH-type containing 7A
chr22_+_21921994 15.75 ENST00000545681.1
ubiquitin-conjugating enzyme E2L 3
chr9_+_140149625 15.73 ENST00000343053.4
negative elongation factor complex member B
chr3_+_49711391 15.73 ENST00000296456.5
ENST00000449966.1
acylaminoacyl-peptide hydrolase
chr12_+_53342625 15.68 ENST00000388837.2
ENST00000550600.1
ENST00000388835.3
keratin 18
chr3_-_63849571 15.64 ENST00000295899.5
THO complex 7 homolog (Drosophila)
chrX_+_12809463 15.60 ENST00000380663.3
ENST00000380668.5
ENST00000398491.2
ENST00000489404.1
phosphoribosyl pyrophosphate synthetase 2
chr1_+_151372010 15.59 ENST00000290541.6
proteasome (prosome, macropain) subunit, beta type, 4
chr5_-_77072085 15.57 ENST00000518338.2
ENST00000520039.1
ENST00000306388.6
ENST00000520361.1
tubulin folding cofactor A
chr20_-_1373682 15.53 ENST00000381724.3
FK506 binding protein 1A, 12kDa
chr1_+_42922173 15.52 ENST00000455780.1
ENST00000372560.3
ENST00000372561.3
ENST00000372556.3
phosphopantothenoylcysteine synthetase
chr9_-_113018746 15.51 ENST00000374515.5
thioredoxin
chr22_-_39096661 15.48 ENST00000216039.5
Josephin domain containing 1
chr20_+_57226841 15.43 ENST00000358029.4
ENST00000361830.3
syntaxin 16
chr1_-_67896095 15.42 ENST00000370994.4
SERPINE1 mRNA binding protein 1
chr8_+_145149930 15.40 ENST00000318911.4
cytochrome c-1
chr1_+_32479430 15.39 ENST00000327300.7
ENST00000492989.1
KH domain containing, RNA binding, signal transduction associated 1
chr3_+_180630444 15.34 ENST00000491062.1
ENST00000468861.1
ENST00000445140.2
ENST00000484958.1
fragile X mental retardation, autosomal homolog 1
chr13_+_115000384 15.32 ENST00000356221.3
ENST00000375310.1
cell division cycle 16
chr5_-_134734901 15.32 ENST00000312469.4
ENST00000423969.2
H2A histone family, member Y
chr20_+_39657454 15.27 ENST00000361337.2
topoisomerase (DNA) I
chr5_+_145826867 15.26 ENST00000296702.5
ENST00000394421.2
transcription elongation regulator 1
chr3_+_141457030 15.25 ENST00000273480.3
ring finger protein 7

Network of associatons between targets according to the STRING database.

First level regulatory network of ZFX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
13.0 52.0 GO:0019322 pentose biosynthetic process(GO:0019322)
12.5 37.5 GO:2000374 regulation of oxygen metabolic process(GO:2000374)
11.2 33.7 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
11.1 55.5 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
10.7 32.2 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) positive regulation of telomeric DNA binding(GO:1904744)
10.6 42.5 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
10.3 30.9 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
10.1 40.4 GO:0036114 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
9.6 28.9 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
9.6 28.8 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
8.6 34.2 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
8.4 25.2 GO:0007113 endomitotic cell cycle(GO:0007113)
8.1 32.5 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
8.1 32.5 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
7.9 23.8 GO:1904351 negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
7.8 54.8 GO:0000710 meiotic mismatch repair(GO:0000710)
7.5 29.9 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
7.4 22.3 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
7.2 21.6 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
7.1 21.4 GO:0006172 ADP biosynthetic process(GO:0006172)
7.1 21.3 GO:0007290 spermatid nucleus elongation(GO:0007290)
6.9 48.2 GO:0006226 dUMP biosynthetic process(GO:0006226)
6.8 13.5 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
6.7 20.0 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
6.6 33.0 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
6.6 46.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
6.5 19.6 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188)
6.4 64.0 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
6.3 37.7 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
6.2 18.6 GO:1901535 regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536) regulation of genetic imprinting(GO:2000653)
6.1 18.4 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
6.0 18.1 GO:0006404 RNA import into nucleus(GO:0006404)
6.0 18.0 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
5.9 17.7 GO:0090611 mitotic cytokinesis checkpoint(GO:0044878) ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
5.9 17.7 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
5.9 17.7 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
5.9 17.6 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
5.8 46.6 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
5.7 34.3 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
5.7 17.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
5.7 22.6 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
5.6 16.8 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
5.4 21.6 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
5.4 21.5 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
5.1 25.3 GO:0034971 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) histone H3-R17 methylation(GO:0034971)
5.1 20.2 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
5.0 19.9 GO:0043335 protein unfolding(GO:0043335)
4.9 14.8 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
4.9 24.4 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
4.7 42.7 GO:0030091 protein repair(GO:0030091)
4.7 23.6 GO:0075525 viral translational termination-reinitiation(GO:0075525)
4.5 13.4 GO:0015680 intracellular copper ion transport(GO:0015680)
4.4 13.3 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
4.4 192.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
4.4 43.7 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
4.4 65.4 GO:0045116 protein neddylation(GO:0045116)
4.3 12.9 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
4.3 12.9 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
4.3 63.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
4.2 21.2 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
4.2 20.9 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161) regulation of collagen catabolic process(GO:0010710)
4.1 37.2 GO:0010265 SCF complex assembly(GO:0010265)
4.0 32.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
4.0 15.8 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
3.9 54.0 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
3.7 11.2 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
3.7 55.6 GO:0032075 positive regulation of nuclease activity(GO:0032075)
3.7 51.3 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
3.6 14.5 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
3.6 14.4 GO:1903679 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
3.6 10.8 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
3.6 25.2 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
3.6 21.5 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
3.6 57.2 GO:0000338 protein deneddylation(GO:0000338)
3.5 10.6 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
3.5 24.7 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
3.5 10.5 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
3.5 31.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
3.4 13.6 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
3.4 23.8 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
3.4 13.6 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
3.4 6.7 GO:0000183 chromatin silencing at rDNA(GO:0000183)
3.4 13.5 GO:0071373 cellular response to cocaine(GO:0071314) cellular response to luteinizing hormone stimulus(GO:0071373)
3.3 19.9 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
3.3 3.3 GO:0009218 pyrimidine ribonucleotide metabolic process(GO:0009218)
3.3 13.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
3.3 117.1 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
3.2 9.6 GO:2000397 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
3.2 16.0 GO:0061668 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
3.2 9.5 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
3.1 15.6 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
3.1 9.3 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
3.1 21.7 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
3.1 9.2 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
3.0 12.0 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
3.0 36.0 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
3.0 11.9 GO:0015966 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
3.0 8.9 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
3.0 71.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
2.9 8.7 GO:0006014 D-ribose metabolic process(GO:0006014)
2.9 20.0 GO:2000630 positive regulation of miRNA metabolic process(GO:2000630)
2.8 8.5 GO:0061470 T follicular helper cell differentiation(GO:0061470)
2.8 14.1 GO:0009838 abscission(GO:0009838)
2.8 5.5 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
2.7 21.4 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
2.6 21.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
2.6 13.2 GO:0032790 ribosome disassembly(GO:0032790)
2.6 13.1 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
2.6 20.9 GO:0032020 ISG15-protein conjugation(GO:0032020)
2.6 36.4 GO:0006107 oxaloacetate metabolic process(GO:0006107)
2.6 28.6 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
2.6 5.2 GO:0003064 regulation of heart rate by hormone(GO:0003064)
2.6 12.9 GO:0052204 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
2.6 64.6 GO:0006337 nucleosome disassembly(GO:0006337)
2.5 17.8 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
2.5 12.7 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
2.5 10.1 GO:0043248 proteasome assembly(GO:0043248)
2.5 105.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
2.5 7.5 GO:0060920 atrioventricular node development(GO:0003162) cardiac pacemaker cell differentiation(GO:0060920) cardiac pacemaker cell development(GO:0060926)
2.5 10.0 GO:0030242 pexophagy(GO:0030242)
2.5 37.5 GO:0070987 error-free translesion synthesis(GO:0070987)
2.5 5.0 GO:0001923 B-1 B cell differentiation(GO:0001923)
2.5 35.0 GO:0033182 regulation of histone ubiquitination(GO:0033182)
2.5 7.4 GO:0090034 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
2.5 17.2 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
2.4 29.3 GO:0010998 regulation of translational initiation by eIF2 alpha phosphorylation(GO:0010998)
2.4 9.7 GO:0019046 release from viral latency(GO:0019046)
2.4 7.2 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
2.4 9.6 GO:0000103 sulfate assimilation(GO:0000103)
2.4 24.0 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
2.4 7.2 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
2.4 14.2 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
2.3 35.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
2.3 16.4 GO:0008295 spermidine biosynthetic process(GO:0008295)
2.3 4.7 GO:0014040 positive regulation of Schwann cell differentiation(GO:0014040)
2.3 14.0 GO:0046940 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856) nucleoside monophosphate phosphorylation(GO:0046940)
2.3 7.0 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
2.3 215.4 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
2.3 9.3 GO:0021896 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
2.3 4.6 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
2.3 18.3 GO:0007379 segment specification(GO:0007379)
2.3 22.7 GO:0030263 apoptotic chromosome condensation(GO:0030263)
2.3 11.4 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
2.3 18.2 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
2.3 18.1 GO:0060155 platelet dense granule organization(GO:0060155)
2.2 2.2 GO:0031291 Ran protein signal transduction(GO:0031291)
2.2 8.9 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
2.2 8.7 GO:0045218 zonula adherens maintenance(GO:0045218)
2.2 10.8 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
2.1 2.1 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
2.1 12.8 GO:0006741 NADP biosynthetic process(GO:0006741)
2.1 27.7 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
2.1 12.7 GO:0043366 beta selection(GO:0043366)
2.1 12.6 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
2.1 8.2 GO:1900223 positive regulation of beta-amyloid clearance(GO:1900223)
2.1 16.5 GO:0061085 regulation of histone H3-K27 methylation(GO:0061085)
2.0 16.3 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
2.0 6.1 GO:1902960 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
2.0 10.1 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
2.0 9.8 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
1.9 5.8 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
1.9 11.6 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
1.9 54.1 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
1.9 7.7 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
1.9 24.9 GO:0035518 histone H2A monoubiquitination(GO:0035518)
1.9 17.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
1.9 13.4 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
1.9 7.6 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
1.9 11.4 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
1.9 5.7 GO:0006624 vacuolar protein processing(GO:0006624)
1.9 5.6 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
1.9 15.0 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
1.9 5.6 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
1.8 11.1 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
1.8 12.9 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
1.8 3.7 GO:0014042 positive regulation of neuron maturation(GO:0014042)
1.8 7.2 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
1.8 10.7 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
1.8 3.5 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
1.8 38.9 GO:0045948 positive regulation of translational initiation(GO:0045948)
1.8 5.3 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
1.7 5.1 GO:0002906 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
1.7 6.8 GO:1900063 regulation of peroxisome organization(GO:1900063)
1.7 77.4 GO:0006378 mRNA polyadenylation(GO:0006378)
1.7 50.3 GO:0097421 liver regeneration(GO:0097421)
1.7 18.4 GO:0045176 apical protein localization(GO:0045176)
1.7 25.0 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
1.7 3.3 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
1.6 69.3 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
1.6 3.3 GO:0006788 heme oxidation(GO:0006788)
1.6 39.2 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
1.6 8.2 GO:0060356 leucine import(GO:0060356)
1.6 8.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
1.6 43.8 GO:0006622 protein targeting to lysosome(GO:0006622)
1.6 12.9 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
1.6 4.7 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
1.6 4.7 GO:0009080 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080)
1.6 15.6 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
1.6 7.8 GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585)
1.5 27.8 GO:0060148 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
1.5 7.7 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
1.5 10.7 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
1.5 15.3 GO:0006265 DNA topological change(GO:0006265)
1.5 34.9 GO:0016578 histone deubiquitination(GO:0016578)
1.5 15.1 GO:0015939 pantothenate metabolic process(GO:0015939)
1.5 46.8 GO:0035066 positive regulation of histone acetylation(GO:0035066)
1.5 13.5 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
1.5 8.9 GO:0002176 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
1.5 1.5 GO:0061010 gall bladder development(GO:0061010)
1.4 4.3 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
1.4 10.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
1.4 59.7 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
1.4 14.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
1.4 39.3 GO:0097284 hepatocyte apoptotic process(GO:0097284)
1.4 40.5 GO:0051016 barbed-end actin filament capping(GO:0051016)
1.4 14.0 GO:0071578 zinc II ion transmembrane import(GO:0071578)
1.4 15.3 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
1.4 6.9 GO:1902267 polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) negative regulation of polyamine transmembrane transport(GO:1902268)
1.3 4.0 GO:0046060 dATP metabolic process(GO:0046060) dATP catabolic process(GO:0046061)
1.3 20.0 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
1.3 14.7 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
1.3 8.0 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
1.3 69.4 GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
1.3 28.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
1.3 21.2 GO:0090161 Golgi ribbon formation(GO:0090161)
1.3 4.0 GO:0042351 GDP-L-fucose biosynthetic process(GO:0042350) 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
1.3 8.0 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
1.3 6.6 GO:1903525 regulation of membrane tubulation(GO:1903525)
1.3 5.2 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
1.3 13.1 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
1.3 27.4 GO:0006465 signal peptide processing(GO:0006465)
1.3 16.9 GO:0046689 response to mercury ion(GO:0046689)
1.3 5.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
1.3 2.6 GO:0002572 pro-T cell differentiation(GO:0002572)
1.3 66.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
1.2 8.7 GO:0002191 cap-dependent translational initiation(GO:0002191)
1.2 6.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
1.2 27.9 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
1.2 6.1 GO:0097338 response to clozapine(GO:0097338)
1.2 12.0 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
1.2 12.0 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
1.2 4.8 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
1.2 4.8 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
1.2 36.5 GO:0090383 phagosome acidification(GO:0090383)
1.2 2.3 GO:0033522 histone H2A ubiquitination(GO:0033522)
1.2 9.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
1.2 35.7 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
1.1 5.7 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
1.1 11.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
1.1 5.7 GO:0051661 maintenance of centrosome location(GO:0051661)
1.1 2.2 GO:0031125 rRNA 3'-end processing(GO:0031125)
1.1 2.2 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
1.1 5.5 GO:0098502 negative regulation of protein ADP-ribosylation(GO:0010836) DNA dephosphorylation(GO:0098502)
1.1 4.4 GO:0035879 plasma membrane lactate transport(GO:0035879)
1.1 34.0 GO:0016575 histone deacetylation(GO:0016575)
1.1 7.6 GO:0072718 response to cisplatin(GO:0072718)
1.1 4.3 GO:0008063 Toll signaling pathway(GO:0008063)
1.1 7.5 GO:0003415 chondrocyte hypertrophy(GO:0003415)
1.1 4.3 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
1.1 6.4 GO:0046600 negative regulation of centriole replication(GO:0046600)
1.1 4.2 GO:0008298 intracellular mRNA localization(GO:0008298)
1.1 1.1 GO:0048377 lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378) mesendoderm development(GO:0048382)
1.0 7.3 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
1.0 11.3 GO:0010815 bradykinin catabolic process(GO:0010815)
1.0 8.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
1.0 9.2 GO:0006105 succinate metabolic process(GO:0006105)
1.0 6.1 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
1.0 5.1 GO:0035617 stress granule disassembly(GO:0035617)
1.0 18.2 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
1.0 7.9 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
1.0 5.8 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
1.0 6.7 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.9 35.2 GO:0043171 peptide catabolic process(GO:0043171)
0.9 6.5 GO:0031017 exocrine pancreas development(GO:0031017)
0.9 2.8 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.9 8.2 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.9 3.6 GO:0016334 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.9 18.9 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.9 15.2 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.9 4.5 GO:0006538 glutamate catabolic process(GO:0006538)
0.9 6.2 GO:1904666 regulation of ubiquitin protein ligase activity(GO:1904666)
0.9 2.6 GO:0072708 response to sorbitol(GO:0072708)
0.9 10.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.9 5.3 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.9 3.5 GO:1903911 positive regulation of postsynaptic membrane organization(GO:1901628) positive regulation of receptor clustering(GO:1903911)
0.9 30.6 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.9 4.3 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.9 7.8 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.9 6.9 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.9 8.6 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.9 6.0 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.8 10.1 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.8 4.2 GO:0072553 terminal button organization(GO:0072553)
0.8 2.5 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.8 48.3 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.8 10.7 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.8 3.3 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.8 9.0 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.8 8.1 GO:0090344 negative regulation of cell aging(GO:0090344)
0.8 12.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.8 9.7 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.8 7.2 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.8 11.2 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.8 4.8 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.8 2.4 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.8 7.9 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.8 5.5 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.8 8.5 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.8 2.3 GO:1901985 positive regulation of protein acetylation(GO:1901985)
0.8 7.6 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.8 3.0 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.8 52.7 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.7 4.5 GO:0035709 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.7 5.2 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.7 3.7 GO:0090400 stress-induced premature senescence(GO:0090400)
0.7 25.1 GO:0031648 protein destabilization(GO:0031648)
0.7 5.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.7 3.6 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.7 29.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.7 14.5 GO:0032060 bleb assembly(GO:0032060)
0.7 3.6 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.7 1.4 GO:0002351 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.7 5.7 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.7 5.7 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.7 4.9 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.7 3.5 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.7 0.7 GO:0003274 endocardial cushion fusion(GO:0003274)
0.7 5.6 GO:0090382 phagosome maturation(GO:0090382)
0.7 8.3 GO:0070986 left/right axis specification(GO:0070986)
0.7 1.4 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.7 11.7 GO:2000188 regulation of cholesterol homeostasis(GO:2000188)
0.7 14.3 GO:0048745 smooth muscle tissue development(GO:0048745)
0.7 14.9 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.7 10.1 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.7 5.4 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.7 3.3 GO:0003149 membranous septum morphogenesis(GO:0003149)
0.7 18.6 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.7 5.9 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.7 7.8 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.6 31.8 GO:0006611 protein export from nucleus(GO:0006611)
0.6 1.9 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.6 12.0 GO:0050684 regulation of mRNA processing(GO:0050684)
0.6 6.9 GO:0098969 neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540)
0.6 1.9 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.6 15.5 GO:0030033 microvillus assembly(GO:0030033)
0.6 11.7 GO:0071800 podosome assembly(GO:0071800)
0.6 4.9 GO:0000212 meiotic spindle organization(GO:0000212)
0.6 4.9 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.6 2.4 GO:0061146 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.6 12.5 GO:0019372 lipoxygenase pathway(GO:0019372)
0.6 30.1 GO:0045454 cell redox homeostasis(GO:0045454)
0.6 12.9 GO:0051168 nuclear export(GO:0051168)
0.6 19.0 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.6 0.6 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.6 2.3 GO:0042631 cellular response to water deprivation(GO:0042631)
0.6 4.5 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.6 2.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.5 13.6 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.5 47.4 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.5 3.2 GO:0017004 cytochrome complex assembly(GO:0017004)
0.5 4.3 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.5 2.1 GO:0035973 aggrephagy(GO:0035973)
0.5 0.5 GO:0048636 positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863)
0.5 4.8 GO:0051028 mRNA transport(GO:0051028)
0.5 15.3 GO:0001881 receptor recycling(GO:0001881)
0.5 38.2 GO:0070125 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.5 25.9 GO:0032392 DNA geometric change(GO:0032392)
0.5 14.9 GO:2001222 regulation of neuron migration(GO:2001222)
0.5 23.0 GO:0008206 bile acid metabolic process(GO:0008206)
0.5 9.2 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.5 13.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.5 3.9 GO:0043584 nose development(GO:0043584)
0.5 3.9 GO:0009650 UV protection(GO:0009650)
0.5 3.4 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.5 3.9 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.5 9.8 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.5 31.9 GO:0043488 regulation of mRNA stability(GO:0043488)
0.5 5.0 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.4 7.6 GO:0016540 protein autoprocessing(GO:0016540)
0.4 34.9 GO:0006334 nucleosome assembly(GO:0006334)
0.4 14.7 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.4 2.2 GO:0021759 globus pallidus development(GO:0021759)
0.4 3.5 GO:0007032 endosome organization(GO:0007032)
0.4 5.6 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.4 19.9 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.4 12.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.4 0.9 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.4 0.8 GO:0034201 response to oleic acid(GO:0034201)
0.4 5.9 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.4 7.1 GO:0044804 nucleophagy(GO:0044804)
0.4 15.1 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.4 9.7 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.4 3.2 GO:0015816 glycine transport(GO:0015816)
0.4 4.3 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.4 1.5 GO:0038203 TORC2 signaling(GO:0038203)
0.4 1.1 GO:0035803 egg coat formation(GO:0035803)
0.4 6.5 GO:0035065 regulation of histone acetylation(GO:0035065)
0.4 2.3 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.4 10.3 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.4 0.7 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.4 1.4 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.4 3.2 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.3 2.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.3 0.7 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.3 4.0 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.3 1.3 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.3 70.2 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.3 1.0 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.3 3.6 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.3 42.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.3 7.6 GO:0051452 intracellular pH reduction(GO:0051452)
0.3 1.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.3 3.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.3 4.8 GO:0046039 GTP metabolic process(GO:0046039)
0.3 8.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.3 12.5 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.3 1.0 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.3 0.8 GO:0061760 antifungal innate immune response(GO:0061760)
0.3 0.8 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.3 1.0 GO:0002002 regulation of angiotensin levels in blood(GO:0002002) angiotensin maturation(GO:0002003) regulation of angiotensin metabolic process(GO:0060177)
0.3 0.8 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.3 3.3 GO:0002643 regulation of tolerance induction(GO:0002643)
0.2 2.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.2 1.4 GO:0030656 regulation of vitamin metabolic process(GO:0030656)
0.2 14.6 GO:0006968 cellular defense response(GO:0006968)
0.2 1.8 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.2 17.9 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.2 2.4 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.2 0.4 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.2 6.5 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.2 1.7 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.2 4.6 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.2 4.8 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.2 22.0 GO:0007051 spindle organization(GO:0007051)
0.2 5.1 GO:0009081 branched-chain amino acid metabolic process(GO:0009081)
0.2 0.7 GO:0019722 calcium-mediated signaling(GO:0019722)
0.2 0.2 GO:0009447 putrescine catabolic process(GO:0009447)
0.2 2.6 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.2 0.8 GO:0006013 mannose metabolic process(GO:0006013)
0.2 5.2 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.2 3.5 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.2 3.8 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.2 4.8 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.2 1.1 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 3.8 GO:0006270 DNA replication initiation(GO:0006270)
0.1 2.3 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.1 3.2 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.1 4.2 GO:0008213 protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.1 3.3 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 0.8 GO:0030421 defecation(GO:0030421)
0.1 2.2 GO:0046688 response to copper ion(GO:0046688)
0.1 1.8 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.1 6.4 GO:0003407 neural retina development(GO:0003407)
0.1 9.5 GO:0016925 protein sumoylation(GO:0016925)
0.1 57.0 GO:0043312 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.1 1.7 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.9 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 6.7 GO:0097202 activation of cysteine-type endopeptidase activity(GO:0097202)
0.1 0.4 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.1 0.7 GO:0016446 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 1.5 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.1 0.6 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.1 8.0 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.1 16.9 GO:0007018 microtubule-based movement(GO:0007018)
0.1 3.6 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.1 1.9 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.1 1.7 GO:0009251 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 3.9 GO:0006446 regulation of translational initiation(GO:0006446)
0.1 0.7 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 1.4 GO:0006298 mismatch repair(GO:0006298)
0.1 1.4 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.1 1.9 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 8.1 GO:0046034 ATP metabolic process(GO:0046034)
0.1 2.0 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.1 0.7 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1 0.4 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.1 0.1 GO:0009996 negative regulation of cell fate specification(GO:0009996) skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.1 1.2 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.8 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 1.3 GO:0042692 muscle cell differentiation(GO:0042692)
0.1 0.7 GO:0070875 positive regulation of glycogen biosynthetic process(GO:0045725) positive regulation of glycogen metabolic process(GO:0070875)
0.1 0.4 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 2.8 GO:0010634 positive regulation of epithelial cell migration(GO:0010634)
0.0 0.7 GO:0014823 response to activity(GO:0014823)
0.0 0.3 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.4 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.0 0.8 GO:0042572 retinol metabolic process(GO:0042572)
0.0 3.9 GO:0006457 protein folding(GO:0006457)
0.0 0.6 GO:0031958 corticosteroid receptor signaling pathway(GO:0031958) glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.6 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.4 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.5 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.0 0.5 GO:0030888 regulation of B cell proliferation(GO:0030888)
0.0 0.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.1 GO:2000811 negative regulation of anoikis(GO:2000811)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
12.0 48.0 GO:0032301 MutSalpha complex(GO:0032301)
9.9 119.0 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
9.9 29.7 GO:0019034 viral replication complex(GO:0019034)
9.6 28.8 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
8.0 40.2 GO:0035370 UBC13-UEV1A complex(GO:0035370)
7.2 28.9 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
7.0 20.9 GO:0034680 integrin alpha1-beta1 complex(GO:0034665) integrin alpha3-beta1 complex(GO:0034667) integrin alpha8-beta1 complex(GO:0034678) integrin alpha10-beta1 complex(GO:0034680)
6.9 82.9 GO:0031595 nuclear proteasome complex(GO:0031595)
6.9 20.6 GO:0034455 t-UTP complex(GO:0034455)
6.8 47.6 GO:0046581 intercellular canaliculus(GO:0046581)
6.3 25.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
6.2 112.3 GO:0034709 methylosome(GO:0034709)
6.0 30.2 GO:1990425 ryanodine receptor complex(GO:1990425)
5.9 17.8 GO:0005826 actomyosin contractile ring(GO:0005826)
5.2 15.6 GO:0030289 protein phosphatase 4 complex(GO:0030289)
5.2 5.2 GO:0044427 chromosomal part(GO:0044427)
5.2 98.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
5.1 15.3 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
5.1 35.5 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
4.9 44.0 GO:0072546 ER membrane protein complex(GO:0072546)
4.8 43.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
4.7 23.3 GO:0097422 tubular endosome(GO:0097422)
4.6 18.5 GO:1990730 VCP-NSFL1C complex(GO:1990730)
4.5 13.5 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
4.5 31.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
4.3 30.3 GO:0005787 signal peptidase complex(GO:0005787)
4.1 62.2 GO:0090543 Flemming body(GO:0090543)
4.1 40.6 GO:0008290 F-actin capping protein complex(GO:0008290)
3.9 15.6 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
3.9 11.7 GO:0002079 inner acrosomal membrane(GO:0002079)
3.7 111.1 GO:0005680 anaphase-promoting complex(GO:0005680)
3.6 14.4 GO:0031166 integral component of vacuolar membrane(GO:0031166)
3.5 17.5 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
3.5 45.5 GO:0044754 autolysosome(GO:0044754)
3.4 34.5 GO:0070187 telosome(GO:0070187)
3.4 10.3 GO:0031262 Ndc80 complex(GO:0031262)
3.4 34.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
3.4 10.1 GO:0000243 commitment complex(GO:0000243)
3.4 16.8 GO:0097149 centralspindlin complex(GO:0097149)
3.3 10.0 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
3.3 23.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
3.3 32.8 GO:0001739 sex chromatin(GO:0001739)
3.2 12.9 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
3.2 12.9 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
3.2 25.2 GO:0042382 paraspeckles(GO:0042382)
3.1 15.7 GO:0032021 NELF complex(GO:0032021)
3.1 9.3 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
3.0 8.9 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
2.7 59.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
2.7 5.4 GO:1903349 omegasome membrane(GO:1903349)
2.7 18.8 GO:0005956 protein kinase CK2 complex(GO:0005956)
2.6 34.0 GO:0048188 Set1C/COMPASS complex(GO:0048188)
2.5 24.8 GO:0042587 glycogen granule(GO:0042587)
2.4 17.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
2.4 31.5 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
2.3 28.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
2.3 16.3 GO:0016272 prefoldin complex(GO:0016272)
2.3 20.9 GO:0000125 PCAF complex(GO:0000125)
2.3 7.0 GO:0033276 transcription factor TFTC complex(GO:0033276)
2.3 32.3 GO:0044613 nuclear pore central transport channel(GO:0044613)
2.3 16.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
2.3 13.5 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
2.3 13.5 GO:0097208 alveolar lamellar body(GO:0097208)
2.2 15.6 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
2.2 19.9 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
2.2 78.1 GO:0090544 BAF-type complex(GO:0090544)
2.1 10.7 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
2.1 10.7 GO:0044308 axonal spine(GO:0044308)
2.1 10.6 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
2.1 23.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
2.1 48.3 GO:0030127 COPII vesicle coat(GO:0030127)
2.1 20.9 GO:0045180 basal cortex(GO:0045180)
2.1 8.4 GO:0071001 U4/U6 snRNP(GO:0071001)
2.1 22.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
2.1 10.3 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
2.1 12.4 GO:0000124 SAGA complex(GO:0000124)
2.1 8.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
2.0 8.2 GO:0009368 endopeptidase Clp complex(GO:0009368)
2.0 26.4 GO:0097470 ribbon synapse(GO:0097470)
1.9 11.6 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
1.9 13.5 GO:0031415 NatA complex(GO:0031415)
1.9 9.5 GO:0016589 NURF complex(GO:0016589)
1.8 16.5 GO:0035102 PRC1 complex(GO:0035102)
1.8 7.3 GO:0001405 presequence translocase-associated import motor(GO:0001405)
1.8 99.7 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
1.8 7.2 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
1.8 10.7 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
1.8 10.5 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
1.7 40.2 GO:0032156 septin cytoskeleton(GO:0032156)
1.7 21.9 GO:0002199 zona pellucida receptor complex(GO:0002199)
1.7 31.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
1.6 20.9 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
1.6 74.0 GO:0005669 transcription factor TFIID complex(GO:0005669)
1.6 9.6 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
1.6 28.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
1.6 9.4 GO:0032311 angiogenin-PRI complex(GO:0032311)
1.5 77.5 GO:0008180 COP9 signalosome(GO:0008180)
1.5 13.8 GO:0061574 ASAP complex(GO:0061574)
1.5 23.0 GO:0005662 DNA replication factor A complex(GO:0005662)
1.5 9.2 GO:0061700 GATOR2 complex(GO:0061700)
1.5 7.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
1.4 229.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
1.4 33.2 GO:0071010 prespliceosome(GO:0071010)
1.4 24.4 GO:0030014 CCR4-NOT complex(GO:0030014)
1.4 5.7 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
1.4 10.0 GO:0070852 cell body fiber(GO:0070852)
1.4 18.2 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
1.3 24.1 GO:0036020 endolysosome membrane(GO:0036020)
1.3 8.0 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
1.3 81.2 GO:0000502 proteasome complex(GO:0000502)
1.3 17.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
1.3 27.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
1.3 3.9 GO:0001740 Barr body(GO:0001740)
1.3 11.6 GO:0005827 polar microtubule(GO:0005827)
1.3 24.3 GO:0001891 phagocytic cup(GO:0001891)
1.3 25.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
1.3 15.3 GO:0097431 mitotic spindle pole(GO:0097431)
1.3 5.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.2 3.7 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
1.2 4.8 GO:0005846 nuclear cap binding complex(GO:0005846)
1.2 15.6 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
1.2 7.2 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
1.2 20.1 GO:0031616 spindle pole centrosome(GO:0031616)
1.1 10.3 GO:0070652 HAUS complex(GO:0070652)
1.1 3.4 GO:0031523 Myb complex(GO:0031523)
1.1 12.8 GO:0030008 TRAPP complex(GO:0030008)
1.1 1.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
1.0 4.2 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
1.0 5.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
1.0 5.0 GO:0032449 CBM complex(GO:0032449)
1.0 5.9 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
1.0 7.7 GO:0044294 dendritic growth cone(GO:0044294)
1.0 13.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.9 11.1 GO:0010369 chromocenter(GO:0010369)
0.9 6.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.9 8.8 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.9 13.2 GO:0022626 cytosolic ribosome(GO:0022626)
0.9 6.9 GO:0005610 laminin-5 complex(GO:0005610)
0.9 66.3 GO:0070469 respiratory chain(GO:0070469)
0.8 2.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.8 1.7 GO:0035189 Rb-E2F complex(GO:0035189)
0.8 33.2 GO:0005844 polysome(GO:0005844)
0.8 24.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.8 39.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.8 12.9 GO:0031519 PcG protein complex(GO:0031519)
0.8 9.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.8 88.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.8 4.8 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.8 8.8 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.8 22.9 GO:0030686 90S preribosome(GO:0030686)
0.8 5.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.8 17.1 GO:0035371 microtubule plus-end(GO:0035371)
0.8 8.5 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.8 69.0 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.8 3.8 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.8 6.1 GO:0005642 annulate lamellae(GO:0005642)
0.8 34.1 GO:0045095 keratin filament(GO:0045095)
0.7 2.2 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.7 6.7 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.7 8.7 GO:0005915 zonula adherens(GO:0005915)
0.7 14.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.7 3.6 GO:0042643 actomyosin, actin portion(GO:0042643)
0.7 2.9 GO:0033553 rDNA heterochromatin(GO:0033553)
0.7 5.0 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.7 5.7 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.7 9.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.7 8.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.7 79.9 GO:0016605 PML body(GO:0016605)
0.7 102.2 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.7 3.3 GO:0032009 early phagosome(GO:0032009)
0.6 9.1 GO:0042588 zymogen granule(GO:0042588)
0.6 20.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.6 8.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.6 13.0 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.6 11.1 GO:0031089 platelet dense granule lumen(GO:0031089)
0.6 6.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.6 15.0 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.6 9.3 GO:0035861 site of double-strand break(GO:0035861)
0.6 23.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.6 42.6 GO:0005811 lipid particle(GO:0005811)
0.6 5.7 GO:1990909 Wnt signalosome(GO:1990909)
0.6 5.1 GO:0035253 ciliary rootlet(GO:0035253)
0.5 22.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.5 2.1 GO:0032044 DSIF complex(GO:0032044)
0.5 15.8 GO:1904115 axon cytoplasm(GO:1904115)
0.5 2.5 GO:0030893 meiotic cohesin complex(GO:0030893)
0.5 3.5 GO:0042581 specific granule(GO:0042581)
0.5 9.0 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.5 35.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.5 10.1 GO:0032993 protein-DNA complex(GO:0032993)
0.5 6.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.5 18.2 GO:0031201 SNARE complex(GO:0031201)
0.5 17.2 GO:0002102 podosome(GO:0002102)
0.5 9.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.4 4.5 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.4 6.7 GO:0051233 spindle midzone(GO:0051233)
0.4 5.8 GO:0031932 TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.4 1.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.4 17.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.4 15.5 GO:0035577 azurophil granule membrane(GO:0035577)
0.4 1.3 GO:0001652 granular component(GO:0001652)
0.4 20.3 GO:0005801 cis-Golgi network(GO:0005801)
0.4 4.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.4 2.0 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.4 19.9 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.4 18.6 GO:0035579 specific granule membrane(GO:0035579)
0.4 7.2 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.4 4.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.4 8.8 GO:0097228 sperm principal piece(GO:0097228)
0.4 9.3 GO:0042101 T cell receptor complex(GO:0042101)
0.4 8.9 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.3 34.1 GO:0070821 tertiary granule membrane(GO:0070821)
0.3 96.4 GO:0019866 organelle inner membrane(GO:0019866)
0.3 26.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.3 15.5 GO:0045171 intercellular bridge(GO:0045171)
0.3 10.9 GO:0015030 Cajal body(GO:0015030)
0.3 0.6 GO:0034657 GID complex(GO:0034657)
0.3 14.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.3 4.9 GO:0030056 hemidesmosome(GO:0030056)
0.3 2.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.3 1.5 GO:0070826 paraferritin complex(GO:0070826)
0.3 1.4 GO:0030904 retromer complex(GO:0030904)
0.3 63.5 GO:0034774 secretory granule lumen(GO:0034774)
0.2 39.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.2 38.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.2 0.9 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 1.7 GO:0097539 ciliary transition fiber(GO:0097539)
0.2 9.6 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.2 0.4 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.2 5.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.2 4.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 0.7 GO:0030891 VCB complex(GO:0030891)
0.2 0.3 GO:1990075 periciliary membrane compartment(GO:1990075)
0.2 51.2 GO:0016607 nuclear speck(GO:0016607)
0.2 61.2 GO:0005635 nuclear envelope(GO:0005635)
0.2 22.4 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.2 3.5 GO:0005840 ribosome(GO:0005840)
0.2 3.3 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.2 15.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.2 0.3 GO:0033186 CAF-1 complex(GO:0033186)
0.1 6.4 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 2.2 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 11.4 GO:1902494 catalytic complex(GO:1902494)
0.1 5.0 GO:0016592 mediator complex(GO:0016592)
0.1 8.9 GO:0031902 late endosome membrane(GO:0031902)
0.1 7.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 1.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 3.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 0.6 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.1 2.0 GO:0000793 condensed chromosome(GO:0000793)
0.1 5.0 GO:0016363 nuclear matrix(GO:0016363)
0.1 4.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.8 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 1.7 GO:0030673 axolemma(GO:0030673)
0.1 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 9.9 GO:0005925 focal adhesion(GO:0005925)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 1.4 GO:0031970 organelle envelope lumen(GO:0031970)
0.0 2.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.8 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.2 GO:0072686 mitotic spindle(GO:0072686)
0.0 4.2 GO:0010008 endosome membrane(GO:0010008)
0.0 0.3 GO:0000786 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
12.0 48.2 GO:0004132 dCMP deaminase activity(GO:0004132)
12.0 48.0 GO:0032143 single thymine insertion binding(GO:0032143)
11.3 11.3 GO:0001222 transcription corepressor binding(GO:0001222)
11.3 45.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
11.2 33.7 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
10.6 42.5 GO:0034057 RNA strand-exchange activity(GO:0034057)
9.6 28.9 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
9.6 28.8 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
9.3 37.3 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
9.3 37.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
9.1 64.0 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
9.1 36.5 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
8.4 25.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
8.2 24.5 GO:0017130 poly(C) RNA binding(GO:0017130)
8.1 32.5 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
7.7 61.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
7.6 53.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
7.5 22.6 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
6.9 48.1 GO:0033592 RNA strand annealing activity(GO:0033592)
6.6 33.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
6.5 38.9 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
6.5 71.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
6.3 31.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
6.0 18.0 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
5.8 23.1 GO:0016531 copper chaperone activity(GO:0016531)
5.7 17.1 GO:0003883 CTP synthase activity(GO:0003883)
5.5 16.5 GO:0033149 FFAT motif binding(GO:0033149)
5.5 16.4 GO:0004766 spermidine synthase activity(GO:0004766)
5.1 15.4 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
5.0 14.9 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
4.9 14.7 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
4.9 14.7 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
4.5 18.2 GO:0005046 KDEL sequence binding(GO:0005046)
4.5 134.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
4.4 70.1 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
4.3 199.6 GO:0061650 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
4.3 12.9 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
4.2 55.0 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
4.2 25.2 GO:0044388 small protein activating enzyme binding(GO:0044388)
4.2 20.9 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
4.0 40.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
4.0 27.9 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
3.9 27.5 GO:0050733 RS domain binding(GO:0050733)
3.9 39.2 GO:1990446 U1 snRNP binding(GO:1990446)
3.8 15.3 GO:0071987 WD40-repeat domain binding(GO:0071987)
3.7 11.2 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
3.7 11.0 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
3.6 10.8 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
3.6 10.7 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
3.3 13.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
3.2 12.9 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
3.2 9.7 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
3.2 9.6 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
3.2 31.9 GO:0031386 protein tag(GO:0031386)
3.1 9.3 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
3.1 9.3 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
3.0 17.8 GO:0047685 amine sulfotransferase activity(GO:0047685)
3.0 8.9 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
3.0 59.3 GO:0043495 protein anchor(GO:0043495)
2.9 5.8 GO:0043398 HLH domain binding(GO:0043398)
2.9 8.7 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
2.9 23.0 GO:0043024 ribosomal small subunit binding(GO:0043024)
2.9 20.0 GO:0004849 uridine kinase activity(GO:0004849)
2.7 8.2 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
2.7 8.2 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
2.7 32.3 GO:0005131 growth hormone receptor binding(GO:0005131)
2.6 92.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
2.6 49.4 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
2.6 15.6 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
2.6 28.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
2.5 15.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
2.4 7.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
2.4 14.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
2.3 23.5 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
2.3 16.2 GO:0050815 phosphoserine binding(GO:0050815)
2.3 20.7 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
2.2 6.7 GO:0032184 SUMO polymer binding(GO:0032184)
2.2 48.4 GO:0008242 omega peptidase activity(GO:0008242)
2.2 17.4 GO:0070087 chromo shadow domain binding(GO:0070087)
2.1 6.4 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
2.1 61.9 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
2.1 48.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
2.1 4.1 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
2.0 8.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
2.0 14.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
2.0 59.6 GO:0008301 DNA binding, bending(GO:0008301)
2.0 7.9 GO:1903135 cupric ion binding(GO:1903135)
1.9 9.5 GO:0008420 CTD phosphatase activity(GO:0008420)
1.9 9.3 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
1.8 18.5 GO:0019784 NEDD8-specific protease activity(GO:0019784)
1.8 5.5 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
1.8 10.6 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
1.8 74.0 GO:0008536 Ran GTPase binding(GO:0008536)
1.8 38.7 GO:0000339 RNA cap binding(GO:0000339)
1.7 10.3 GO:0010997 anaphase-promoting complex binding(GO:0010997)
1.7 15.3 GO:0000182 rDNA binding(GO:0000182)
1.7 27.1 GO:0097602 cullin family protein binding(GO:0097602)
1.7 16.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
1.7 78.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
1.6 4.9 GO:0031859 platelet activating factor receptor binding(GO:0031859)
1.6 28.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
1.6 3.2 GO:0031177 phosphopantetheine binding(GO:0031177)
1.6 17.2 GO:0051434 BH3 domain binding(GO:0051434)
1.5 39.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
1.5 6.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
1.5 15.0 GO:0008641 small protein activating enzyme activity(GO:0008641)
1.5 12.0 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
1.5 41.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
1.5 6.0 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
1.5 17.8 GO:0004017 adenylate kinase activity(GO:0004017)
1.5 16.4 GO:0046790 virion binding(GO:0046790)
1.5 111.1 GO:0019003 GDP binding(GO:0019003)
1.5 7.4 GO:0030911 TPR domain binding(GO:0030911)
1.5 5.9 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
1.5 1.5 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
1.5 38.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
1.4 10.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
1.4 7.2 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
1.4 5.7 GO:0019237 centromeric DNA binding(GO:0019237)
1.4 11.4 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
1.4 7.0 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
1.4 4.2 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
1.4 5.5 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
1.4 6.9 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
1.4 47.9 GO:0051059 NF-kappaB binding(GO:0051059)
1.4 17.8 GO:0050786 RAGE receptor binding(GO:0050786)
1.4 6.8 GO:0070728 leucine binding(GO:0070728)
1.3 4.0 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
1.3 17.2 GO:0008266 poly(U) RNA binding(GO:0008266)
1.3 21.1 GO:0008494 translation activator activity(GO:0008494)
1.3 5.2 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
1.3 5.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
1.3 7.7 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
1.3 5.1 GO:0099609 microtubule lateral binding(GO:0099609)
1.3 37.9 GO:0070064 proline-rich region binding(GO:0070064)
1.3 66.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
1.2 4.9 GO:0032810 sterol response element binding(GO:0032810)
1.2 9.8 GO:1901611 phosphatidylglycerol binding(GO:1901611)
1.2 14.6 GO:0045295 gamma-catenin binding(GO:0045295)
1.2 8.4 GO:0030621 U4 snRNA binding(GO:0030621)
1.2 10.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
1.2 73.8 GO:0003727 single-stranded RNA binding(GO:0003727)
1.2 23.6 GO:0008603 cAMP-dependent protein kinase inhibitor activity(GO:0004862) cAMP-dependent protein kinase regulator activity(GO:0008603)
1.2 31.8 GO:0051010 microtubule plus-end binding(GO:0051010)
1.2 3.5 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
1.2 4.7 GO:0004530 deoxyribonuclease I activity(GO:0004530)
1.2 65.3 GO:0003743 translation initiation factor activity(GO:0003743)
1.1 11.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
1.1 7.8 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
1.1 13.4 GO:0001056 RNA polymerase III activity(GO:0001056)
1.1 8.9 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
1.1 8.8 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
1.1 3.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
1.1 28.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
1.1 5.4 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
1.1 4.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
1.1 21.3 GO:0016881 acid-amino acid ligase activity(GO:0016881)
1.1 21.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
1.0 4.2 GO:0052812 phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
1.0 13.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
1.0 16.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
1.0 9.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
1.0 22.0 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
1.0 28.0 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.0 16.9 GO:0005537 mannose binding(GO:0005537)
1.0 10.9 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
1.0 15.8 GO:0031996 thioesterase binding(GO:0031996)
1.0 6.9 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
1.0 9.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
1.0 5.8 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
1.0 4.8 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
1.0 2.9 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
1.0 7.6 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.9 7.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.9 9.4 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.9 3.8 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.9 15.9 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.9 3.7 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.9 6.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.9 18.6 GO:0001055 RNA polymerase II activity(GO:0001055)
0.9 4.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.9 49.8 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.9 5.2 GO:0004673 phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673)
0.9 5.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.9 16.2 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.8 2.5 GO:0036033 mediator complex binding(GO:0036033)
0.8 5.0 GO:0019776 Atg8 ligase activity(GO:0019776)
0.8 14.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.8 24.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.8 5.8 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.8 168.9 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.8 4.0 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.8 8.0 GO:0043274 phospholipase binding(GO:0043274)
0.8 24.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.8 2.3 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.8 24.2 GO:0002039 p53 binding(GO:0002039)
0.7 2.2 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.7 4.5 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.7 6.7 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.7 14.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.7 2.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.7 2.2 GO:0015288 porin activity(GO:0015288)
0.7 12.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.7 22.2 GO:0015248 sterol transporter activity(GO:0015248)
0.7 9.0 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.7 6.9 GO:0042731 PH domain binding(GO:0042731)
0.7 25.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.7 15.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.7 21.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.7 6.1 GO:0034452 dynactin binding(GO:0034452)
0.7 27.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.7 8.7 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.7 8.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.7 28.3 GO:0050699 WW domain binding(GO:0050699)
0.7 3.3 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.7 7.9 GO:0051787 misfolded protein binding(GO:0051787)
0.6 2.6 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.6 9.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.6 16.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.6 1.9 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.6 11.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.6 7.6 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.6 3.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.6 8.6 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.6 3.7 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.6 25.0 GO:0030544 Hsp70 protein binding(GO:0030544)
0.6 4.8 GO:0004111 creatine kinase activity(GO:0004111)
0.6 29.9 GO:0019894 kinesin binding(GO:0019894)
0.6 8.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.6 3.5 GO:0003680 AT DNA binding(GO:0003680)
0.6 5.1 GO:0044548 S100 protein binding(GO:0044548)
0.6 34.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.6 2.8 GO:0008097 5S rRNA binding(GO:0008097)
0.6 3.9 GO:0016301 kinase activity(GO:0016301)
0.5 2.2 GO:0004046 aminoacylase activity(GO:0004046)
0.5 3.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.5 10.6 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.5 4.8 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.5 28.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.5 96.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.5 6.3 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.5 5.2 GO:0004697 protein kinase C activity(GO:0004697)
0.5 9.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.5 175.1 GO:0045296 cadherin binding(GO:0045296)
0.5 169.1 GO:0003713 transcription coactivator activity(GO:0003713)
0.5 8.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.5 8.4 GO:0019843 rRNA binding(GO:0019843)
0.5 73.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.5 1.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.5 4.8 GO:0030274 LIM domain binding(GO:0030274)
0.5 3.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.5 1.4 GO:0015235 cobalamin transporter activity(GO:0015235)
0.5 4.5 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.5 9.9 GO:0004707 MAP kinase activity(GO:0004707)
0.4 4.5 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.4 472.6 GO:0003723 RNA binding(GO:0003723)
0.4 3.9 GO:0051400 BH domain binding(GO:0051400)
0.4 5.6 GO:0070410 co-SMAD binding(GO:0070410)
0.4 6.1 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.4 7.3 GO:0005523 tropomyosin binding(GO:0005523)
0.4 5.3 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.4 3.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.4 2.8 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.4 1.6 GO:0031685 adenosine receptor binding(GO:0031685)
0.4 3.4 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.4 1.5 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.4 3.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.4 1.4 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.4 3.2 GO:0032183 SUMO binding(GO:0032183)
0.4 5.0 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.3 11.2 GO:0008276 protein methyltransferase activity(GO:0008276)
0.3 4.7 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.3 4.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.3 2.3 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.3 3.7 GO:0042834 peptidoglycan binding(GO:0042834)
0.3 1.8 GO:0045569 TRAIL binding(GO:0045569)
0.3 11.5 GO:0003678 DNA helicase activity(GO:0003678)
0.3 2.4 GO:0043559 insulin binding(GO:0043559)
0.3 2.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.3 1.5 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.3 1.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.3 4.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.3 7.7 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.3 12.1 GO:0003777 microtubule motor activity(GO:0003777)
0.2 2.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.2 1.7 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.2 5.7 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 0.7 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 3.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.2 7.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.2 6.2 GO:0042605 peptide antigen binding(GO:0042605)
0.2 4.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 2.2 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.2 0.6 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.2 0.7 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 1.1 GO:0032190 acrosin binding(GO:0032190)
0.2 5.6 GO:0005109 frizzled binding(GO:0005109)
0.2 1.4 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 13.8 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.2 2.0 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 2.2 GO:0005123 death receptor binding(GO:0005123)
0.1 2.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 2.4 GO:0070063 RNA polymerase binding(GO:0070063)
0.1 0.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 4.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 2.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 5.0 GO:0051287 NAD binding(GO:0051287)
0.1 1.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 9.4 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 2.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 16.1 GO:0003823 antigen binding(GO:0003823)
0.1 0.9 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1 0.2 GO:0070405 ammonium ion binding(GO:0070405)
0.1 0.4 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 11.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 5.5 GO:0008565 protein transporter activity(GO:0008565)
0.1 4.6 GO:0051082 unfolded protein binding(GO:0051082)
0.1 4.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.7 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 0.8 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 1.2 GO:0070330 aromatase activity(GO:0070330)
0.1 0.3 GO:0050436 microfibril binding(GO:0050436)
0.1 1.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 2.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 1.0 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.0 0.1 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 31.9 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
3.0 156.7 PID BARD1 PATHWAY BARD1 signaling events
2.3 27.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
2.1 54.0 PID ARF 3PATHWAY Arf1 pathway
2.0 46.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
2.0 18.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
1.9 167.6 PID P53 REGULATION PATHWAY p53 pathway
1.8 30.2 PID ALK2 PATHWAY ALK2 signaling events
1.7 42.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
1.7 139.5 PID ATF2 PATHWAY ATF-2 transcription factor network
1.5 197.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
1.5 21.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
1.5 33.1 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
1.4 50.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
1.3 53.9 PID REELIN PATHWAY Reelin signaling pathway
1.3 32.8 PID ATM PATHWAY ATM pathway
1.2 118.7 PID AR PATHWAY Coregulation of Androgen receptor activity
1.1 83.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.9 55.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.9 64.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.9 9.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.8 37.0 PID AURORA B PATHWAY Aurora B signaling
0.8 14.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.8 23.5 PID ATR PATHWAY ATR signaling pathway
0.7 11.1 PID FOXO PATHWAY FoxO family signaling
0.7 35.2 PID PLK1 PATHWAY PLK1 signaling events
0.7 57.2 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.7 44.9 PID NOTCH PATHWAY Notch signaling pathway
0.6 5.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.6 34.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.6 20.8 PID EPHB FWD PATHWAY EPHB forward signaling
0.6 11.7 PID ALK1 PATHWAY ALK1 signaling events
0.6 23.9 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.6 16.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.6 28.3 PID LKB1 PATHWAY LKB1 signaling events
0.6 16.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.6 5.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.5 18.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.5 16.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.5 13.5 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.5 6.7 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.5 41.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.5 6.8 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.4 3.5 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.4 25.5 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.4 4.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.4 10.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.3 4.3 PID CD40 PATHWAY CD40/CD40L signaling
0.3 20.0 PID E2F PATHWAY E2F transcription factor network
0.3 9.9 PID CDC42 PATHWAY CDC42 signaling events
0.3 12.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.3 0.5 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.3 6.3 PID FAS PATHWAY FAS (CD95) signaling pathway
0.3 16.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.3 9.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.3 5.6 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.2 3.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 4.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 4.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.2 7.7 PID IL1 PATHWAY IL1-mediated signaling events
0.2 9.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 2.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.2 11.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 1.8 PID TRAIL PATHWAY TRAIL signaling pathway
0.2 6.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.2 8.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.2 9.4 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.2 3.9 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 1.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 3.2 PID ARF6 PATHWAY Arf6 signaling events
0.1 5.2 PID P73PATHWAY p73 transcription factor network
0.1 1.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 4.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 2.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 3.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 1.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.1 PID BMP PATHWAY BMP receptor signaling
0.0 0.9 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.1 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 45.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
3.5 41.8 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
3.5 271.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
3.3 86.3 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
3.1 116.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
3.1 34.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
2.8 96.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
2.8 52.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
2.6 36.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
2.6 69.3 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
2.5 39.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
2.4 7.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
2.2 60.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
2.1 37.0 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
2.0 36.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
2.0 24.0 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
2.0 25.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
2.0 41.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
1.9 38.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
1.9 18.8 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
1.8 21.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
1.8 96.4 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
1.7 38.1 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
1.7 10.3 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
1.7 22.2 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
1.7 133.1 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
1.7 58.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
1.7 191.3 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
1.6 27.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
1.5 183.8 REACTOME INFLUENZA LIFE CYCLE Genes involved in Influenza Life Cycle
1.5 7.7 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
1.5 67.1 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
1.5 16.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
1.5 7.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
1.4 1.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
1.4 17.1 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
1.4 19.7 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
1.4 57.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
1.4 30.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
1.4 27.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
1.3 57.7 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
1.3 194.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
1.3 7.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
1.2 24.5 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
1.1 12.6 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
1.1 13.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
1.1 38.8 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
1.1 26.3 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
1.1 5.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
1.1 91.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
1.0 30.2 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
1.0 27.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
1.0 22.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
1.0 27.9 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
1.0 23.8 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.9 58.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.9 19.8 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.9 34.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.9 13.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.9 14.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.9 17.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.8 5.0 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.8 21.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.7 14.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.7 17.0 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.7 10.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.7 5.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.6 57.3 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.6 19.1 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.6 14.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.6 15.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.6 13.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.6 15.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.6 11.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.5 10.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.5 7.1 REACTOME PROTEIN FOLDING Genes involved in Protein folding
0.5 7.5 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.5 7.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.5 7.5 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.5 14.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.4 5.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.4 8.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.4 10.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.4 6.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.4 5.7 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.4 7.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.4 2.1 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.4 11.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.4 10.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.4 9.2 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.4 7.1 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.4 67.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.4 5.0 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.4 14.7 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.4 6.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.4 8.7 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.3 15.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.3 10.7 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.3 30.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.3 7.8 REACTOME KINESINS Genes involved in Kinesins
0.3 6.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.3 9.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.3 5.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.3 4.8 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.2 21.3 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.2 16.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 10.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.2 2.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 2.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 2.2 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.2 6.7 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.2 6.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 5.0 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 12.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 2.0 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 1.9 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 1.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 3.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 2.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 1.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.9 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 3.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 1.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.7 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.6 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 2.7 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates