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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ZNF350

Z-value: 0.63

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Transcription factors associated with ZNF350

Gene Symbol Gene ID Gene Info
ZNF350
ENSG00000256683.2 zinc finger protein 350

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF350hg19_v2_chr19_-_52489923_524901130.426.9e-11Click!

Activity profile of ZNF350 motif

Sorted Z-values of ZNF350 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_120133661 14.76 ENST00000503243.1
ENST00000326780.3
RP11-455G16.1
Uncharacterized protein
chr3_-_155524049 13.30 ENST00000534941.1
ENST00000340171.2
C3orf33
chromosome 3 open reading frame 33
chr16_-_46865047 12.29 ENST00000394806.2
C16orf87
chromosome 16 open reading frame 87
chr17_-_18950310 8.95 ENST00000573099.1
GRAP
GRB2-related adaptor protein
chr2_+_233497931 8.40 ENST00000264059.3
EFHD1
EF-hand domain family, member D1
chr1_+_204797749 8.40 ENST00000367172.4
ENST00000367171.4
ENST00000367170.4
ENST00000338515.6
ENST00000339876.6
ENST00000338586.6
ENST00000539706.1
ENST00000360049.4
ENST00000367169.4
ENST00000446412.1
ENST00000403080.1
NFASC
neurofascin
chr12_+_113376249 7.35 ENST00000551007.1
ENST00000548514.1
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr19_+_2977444 7.19 ENST00000246112.4
ENST00000453329.1
ENST00000482627.1
ENST00000452088.1
TLE6
transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
chr11_-_63381925 5.48 ENST00000415826.1
PLA2G16
phospholipase A2, group XVI
chr14_+_76618242 5.31 ENST00000557542.1
ENST00000557263.1
ENST00000557207.1
ENST00000312858.5
ENST00000261530.7
GPATCH2L
G patch domain containing 2-like
chr19_-_4535233 5.14 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5
perilipin 5
chrX_+_56259316 5.05 ENST00000468660.1
KLF8
Kruppel-like factor 8
chr11_-_64511789 5.02 ENST00000419843.1
ENST00000394430.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr11_-_63381823 4.84 ENST00000323646.5
PLA2G16
phospholipase A2, group XVI
chrX_-_47479246 4.83 ENST00000295987.7
ENST00000340666.4
SYN1
synapsin I
chr19_+_5681011 4.73 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
HSD11B1L
hydroxysteroid (11-beta) dehydrogenase 1-like
chr19_+_49866851 4.71 ENST00000221498.2
ENST00000596402.1
DKKL1
dickkopf-like 1
chr19_+_49866331 4.67 ENST00000597873.1
DKKL1
dickkopf-like 1
chr11_-_327537 4.63 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr2_-_241759622 4.52 ENST00000320389.7
ENST00000498729.2
KIF1A
kinesin family member 1A
chr19_-_17488143 4.34 ENST00000599426.1
ENST00000252590.4
PLVAP
plasmalemma vesicle associated protein
chr15_-_43029252 4.30 ENST00000563260.1
ENST00000356231.3
CDAN1
codanin 1
chr11_-_7041466 4.08 ENST00000536068.1
ENST00000278314.4
ZNF214
zinc finger protein 214
chr17_-_74449252 3.95 ENST00000319380.7
UBE2O
ubiquitin-conjugating enzyme E2O
chr1_-_33647267 3.94 ENST00000291416.5
TRIM62
tripartite motif containing 62
chr11_-_45687128 3.90 ENST00000308064.2
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr12_-_93323013 3.84 ENST00000322349.8
EEA1
early endosome antigen 1
chr7_+_2559399 3.70 ENST00000222725.5
ENST00000359574.3
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr12_+_81471816 3.68 ENST00000261206.3
ACSS3
acyl-CoA synthetase short-chain family member 3
chr19_-_5680499 3.55 ENST00000587589.1
C19orf70
chromosome 19 open reading frame 70
chr20_+_4667094 3.54 ENST00000424424.1
ENST00000457586.1
PRNP
prion protein
chr20_+_44035200 3.48 ENST00000372717.1
ENST00000360981.4
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr2_-_9143786 3.41 ENST00000462696.1
ENST00000305997.3
MBOAT2
membrane bound O-acyltransferase domain containing 2
chr17_-_18950950 3.37 ENST00000284154.5
GRAP
GRB2-related adaptor protein
chr10_-_15762124 3.31 ENST00000378076.3
ITGA8
integrin, alpha 8
chr16_+_69600209 3.23 ENST00000566899.1
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr13_+_50202435 3.16 ENST00000282026.1
ARL11
ADP-ribosylation factor-like 11
chr4_+_75858290 3.12 ENST00000513238.1
PARM1
prostate androgen-regulated mucin-like protein 1
chr4_+_75858318 3.04 ENST00000307428.7
PARM1
prostate androgen-regulated mucin-like protein 1
chr17_-_62340581 3.02 ENST00000258991.3
ENST00000583738.1
ENST00000584379.1
TEX2
testis expressed 2
chr17_-_6554877 2.99 ENST00000225728.3
ENST00000575197.1
MED31
mediator complex subunit 31
chr2_-_157198860 2.98 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr1_+_156611704 2.97 ENST00000329117.5
BCAN
brevican
chr16_+_69600058 2.91 ENST00000393742.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr20_-_35374456 2.81 ENST00000373803.2
ENST00000359675.2
ENST00000540765.1
ENST00000349004.1
NDRG3
NDRG family member 3
chr20_+_44035847 2.80 ENST00000372712.2
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr1_+_29213678 2.76 ENST00000347529.3
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr19_+_1450112 2.71 ENST00000590469.1
ENST00000233607.2
ENST00000238483.4
ENST00000590877.1
APC2
adenomatosis polyposis coli 2
chr1_-_200379129 2.71 ENST00000367353.1
ZNF281
zinc finger protein 281
chr6_-_28303901 2.70 ENST00000439158.1
ENST00000446474.1
ENST00000414431.1
ENST00000344279.6
ENST00000453745.1
ZSCAN31
zinc finger and SCAN domain containing 31
chr6_-_56707943 2.67 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
DST
dystonin
chr11_+_64323428 2.66 ENST00000377581.3
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chrX_-_17878827 2.50 ENST00000360011.1
RAI2
retinoic acid induced 2
chr11_+_118826999 2.47 ENST00000264031.2
UPK2
uroplakin 2
chr16_+_2479390 2.45 ENST00000397066.4
CCNF
cyclin F
chr17_-_8093471 2.44 ENST00000389017.4
C17orf59
chromosome 17 open reading frame 59
chr22_+_22020273 2.41 ENST00000412327.1
ENST00000335025.8
ENST00000398831.3
ENST00000492445.2
ENST00000458567.1
ENST00000406385.1
PPIL2
peptidylprolyl isomerase (cyclophilin)-like 2
chr11_+_64323156 2.41 ENST00000377585.3
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr11_-_9113137 2.37 ENST00000520467.1
ENST00000309263.3
ENST00000457346.2
SCUBE2
signal peptide, CUB domain, EGF-like 2
chr1_+_156611960 2.35 ENST00000361588.5
BCAN
brevican
chr11_-_112034803 2.27 ENST00000528832.1
IL18
interleukin 18 (interferon-gamma-inducing factor)
chr1_-_200379104 2.24 ENST00000367352.3
ZNF281
zinc finger protein 281
chr11_-_112034780 2.22 ENST00000524595.1
IL18
interleukin 18 (interferon-gamma-inducing factor)
chr20_+_62367989 2.15 ENST00000309546.3
LIME1
Lck interacting transmembrane adaptor 1
chr11_-_8954491 2.09 ENST00000526227.1
ENST00000525780.1
ENST00000326053.5
C11orf16
chromosome 11 open reading frame 16
chr1_-_200379180 2.08 ENST00000294740.3
ZNF281
zinc finger protein 281
chr12_+_113376157 2.02 ENST00000228928.7
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr12_+_50451462 1.98 ENST00000447966.2
ASIC1
acid-sensing (proton-gated) ion channel 1
chr11_+_8932715 1.94 ENST00000529876.1
ENST00000525005.1
ENST00000524577.1
ENST00000534506.1
AKIP1
A kinase (PRKA) interacting protein 1
chr4_-_99578789 1.94 ENST00000511651.1
ENST00000505184.1
TSPAN5
tetraspanin 5
chr14_+_96671016 1.85 ENST00000542454.2
ENST00000554311.1
ENST00000306005.3
ENST00000539359.1
ENST00000553811.1
BDKRB2
RP11-404P21.8
bradykinin receptor B2
Uncharacterized protein
chr11_+_68671310 1.84 ENST00000255078.3
ENST00000539224.1
IGHMBP2
immunoglobulin mu binding protein 2
chr11_-_112034831 1.83 ENST00000280357.7
IL18
interleukin 18 (interferon-gamma-inducing factor)
chr1_-_204654481 1.80 ENST00000367176.3
LRRN2
leucine rich repeat neuronal 2
chr17_+_68071458 1.72 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr2_-_21266935 1.70 ENST00000233242.1
APOB
apolipoprotein B
chr15_+_42694573 1.68 ENST00000397200.4
ENST00000569827.1
CAPN3
calpain 3, (p94)
chr18_+_77155856 1.59 ENST00000253506.5
ENST00000591814.1
NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr2_-_70780770 1.58 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
TGFA
transforming growth factor, alpha
chr19_+_42829702 1.58 ENST00000334370.4
MEGF8
multiple EGF-like-domains 8
chr1_+_63788730 1.57 ENST00000371116.2
FOXD3
forkhead box D3
chr11_-_62473776 1.53 ENST00000278893.7
ENST00000407022.3
ENST00000421906.1
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr12_+_8185288 1.48 ENST00000162391.3
FOXJ2
forkhead box J2
chr22_+_26565440 1.45 ENST00000404234.3
ENST00000529632.2
ENST00000360929.3
ENST00000248933.6
ENST00000343706.4
SEZ6L
seizure related 6 homolog (mouse)-like
chr17_+_68165657 1.34 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chrX_+_120181457 1.12 ENST00000328078.1
GLUD2
glutamate dehydrogenase 2
chr1_+_156119798 1.03 ENST00000355014.2
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr17_+_68071389 1.03 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr11_-_62473706 0.97 ENST00000403550.1
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr2_-_219925189 0.96 ENST00000295731.6
IHH
indian hedgehog
chr11_-_9113093 0.95 ENST00000450649.2
SCUBE2
signal peptide, CUB domain, EGF-like 2
chr11_+_48002076 0.93 ENST00000418331.2
ENST00000440289.2
PTPRJ
protein tyrosine phosphatase, receptor type, J
chr13_+_96329381 0.90 ENST00000602402.1
ENST00000376795.6
DNAJC3
DnaJ (Hsp40) homolog, subfamily C, member 3
chr21_-_38639813 0.89 ENST00000309117.6
ENST00000398998.1
DSCR3
Down syndrome critical region gene 3
chr10_-_94003003 0.83 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr20_+_4666882 0.83 ENST00000379440.4
ENST00000430350.2
PRNP
prion protein
chr2_+_177025619 0.83 ENST00000410016.1
HOXD3
homeobox D3
chr11_+_65779283 0.80 ENST00000312134.2
CST6
cystatin E/M
chr4_-_99578776 0.76 ENST00000515287.1
TSPAN5
tetraspanin 5
chr4_+_6784401 0.74 ENST00000425103.1
ENST00000307659.5
KIAA0232
KIAA0232
chr16_+_31225337 0.67 ENST00000322122.3
TRIM72
tripartite motif containing 72
chr17_-_39597173 0.64 ENST00000246646.3
KRT38
keratin 38
chr16_+_67282853 0.60 ENST00000299798.11
SLC9A5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr16_+_14802801 0.43 ENST00000526520.1
ENST00000531598.2
NPIPA3
nuclear pore complex interacting protein family, member A3
chr3_+_50229037 0.33 ENST00000232461.3
ENST00000433068.1
GNAT1
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
chr19_-_49243845 0.31 ENST00000222145.4
RASIP1
Ras interacting protein 1
chr11_+_8932828 0.24 ENST00000530281.1
ENST00000396648.2
ENST00000534147.1
ENST00000529942.1
AKIP1
A kinase (PRKA) interacting protein 1
chr10_+_69644404 0.22 ENST00000212015.6
SIRT1
sirtuin 1
chr12_-_49351148 0.17 ENST00000398092.4
ENST00000539611.1
RP11-302B13.5
ARF3
ADP-ribosylation factor 3
ADP-ribosylation factor 3

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF350

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
1.6 6.3 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
1.5 10.3 GO:0046485 ether lipid metabolic process(GO:0046485)
1.5 4.4 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
1.4 8.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
1.2 7.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
1.0 3.0 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.9 9.4 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.9 3.7 GO:0014807 regulation of somitogenesis(GO:0014807)
0.6 5.1 GO:0015747 urate transport(GO:0015747)
0.5 4.8 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.4 1.6 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.4 1.9 GO:0006642 triglyceride mobilization(GO:0006642)
0.3 1.3 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.3 7.0 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.3 3.7 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.3 2.7 GO:0008090 retrograde axonal transport(GO:0008090)
0.3 1.7 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.3 0.8 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.3 8.6 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.2 2.7 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.2 1.0 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.2 1.6 GO:0050915 sensory perception of sour taste(GO:0050915)
0.2 1.9 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.2 0.9 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.2 4.3 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.2 5.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.2 2.8 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.2 3.9 GO:0006012 galactose metabolic process(GO:0006012)
0.2 0.8 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.2 2.4 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.2 1.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.1 6.1 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 9.4 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 2.1 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.1 13.3 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.1 4.5 GO:0008089 anterograde axonal transport(GO:0008089)
0.1 3.8 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1 3.4 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.1 6.2 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 1.3 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 12.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 3.3 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 0.3 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 2.5 GO:0034389 lipid particle organization(GO:0034389)
0.1 3.0 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.1 3.9 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.6 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.5 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.1 4.3 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 2.7 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 2.7 GO:0010107 potassium ion import(GO:0010107)
0.1 0.7 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.9 GO:0060242 contact inhibition(GO:0060242)
0.1 0.7 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 3.2 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 1.0 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 2.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 1.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.8 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 3.0 GO:0006665 sphingolipid metabolic process(GO:0006665)
0.0 4.5 GO:0006469 negative regulation of protein kinase activity(GO:0006469)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.4 GO:0097454 Schwann cell microvillus(GO:0097454)
1.1 3.3 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.8 3.8 GO:0044308 axonal spine(GO:0044308)
0.7 2.7 GO:0031673 H zone(GO:0031673)
0.6 3.0 GO:0070847 core mediator complex(GO:0070847)
0.4 2.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.3 4.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.2 2.7 GO:0016342 catenin complex(GO:0016342)
0.2 1.7 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 0.9 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.2 1.8 GO:0032797 SMN complex(GO:0032797)
0.1 4.8 GO:0000795 synaptonemal complex(GO:0000795)
0.1 2.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 10.3 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 4.5 GO:1904115 axon cytoplasm(GO:1904115)
0.1 3.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 4.1 GO:0016235 aggresome(GO:0016235)
0.1 6.3 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 7.7 GO:0005796 Golgi lumen(GO:0005796)
0.0 3.0 GO:0030315 T-tubule(GO:0030315)
0.0 0.8 GO:1990124 CCR4-NOT complex(GO:0030014) messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 2.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 10.8 GO:0005770 late endosome(GO:0005770)
0.0 4.3 GO:0005901 caveola(GO:0005901)
0.0 2.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 5.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 3.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.5 GO:0005811 lipid particle(GO:0005811)
0.0 6.8 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.7 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 16.8 GO:0005615 extracellular space(GO:0005615)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 10.3 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
1.7 6.8 GO:0035473 lipase binding(GO:0035473)
0.9 9.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.9 3.7 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.7 4.4 GO:1903135 cupric ion binding(GO:1903135)
0.6 8.4 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.6 1.9 GO:0004947 bradykinin receptor activity(GO:0004947)
0.6 3.9 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.5 5.1 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.4 3.4 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.3 1.6 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.3 1.8 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.3 6.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.3 1.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.2 3.7 GO:0016405 CoA-ligase activity(GO:0016405)
0.2 4.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 0.9 GO:0070097 delta-catenin binding(GO:0070097)
0.2 5.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 2.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.3 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.1 12.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 2.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.7 GO:0031432 titin binding(GO:0031432)
0.1 3.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.3 GO:0000035 acyl binding(GO:0000035)
0.1 2.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 3.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 1.0 GO:0005113 patched binding(GO:0005113)
0.1 1.0 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.6 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 4.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.2 GO:0043398 HLH domain binding(GO:0043398)
0.1 4.5 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.8 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.9 GO:0051787 misfolded protein binding(GO:0051787)
0.0 7.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 6.3 GO:0005125 cytokine activity(GO:0005125)
0.0 3.0 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 6.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 2.7 GO:0008017 microtubule binding(GO:0008017)
0.0 8.4 GO:0005509 calcium ion binding(GO:0005509)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 6.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 5.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 4.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 2.3 PID RAS PATHWAY Regulation of Ras family activation
0.1 2.8 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 5.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 7.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.9 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 10.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.4 3.4 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.3 4.8 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.2 5.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.2 5.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 3.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 14.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 3.9 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 12.3 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.1 1.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 4.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 6.3 REACTOME SIGNALING BY ILS Genes involved in Signaling by Interleukins
0.1 2.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 3.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 3.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 3.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 3.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 4.1 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.4 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 1.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)