Motif ID: AAAGUGC

Z-value: 1.699


Mature miRNA associated with seed AAAGUGC:

NamemiRBase Accession
hsa-miR-106a MIMAT0000103
hsa-miR-106b MIMAT0000680
hsa-miR-17 MIMAT0000070
hsa-miR-20a MIMAT0000075
hsa-miR-20b MIMAT0001413
hsa-miR-519d MIMAT0002853
hsa-miR-93 MIMAT0000093



Activity profile for motif AAAGUGC.

activity profile for motif AAAGUGC


Sorted Z-values histogram for motif AAAGUGC

Sorted Z-values for motif AAAGUGC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAAGUGC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_184943673 12.341 NM_052966
FAM129A
family with sequence similarity 129, member A
chr4_+_74606222 8.192 NM_000584
IL8
interleukin 8
chr16_+_57406398 6.618 NM_002996
CX3CL1
chemokine (C-X3-C motif) ligand 1
chr5_-_131826426 6.548 NM_002198
IRF1
interferon regulatory factor 1
chr2_+_150186498 6.509 NM_001195685
LYPD6
LY6/PLAUR domain containing 6
chr2_+_150187028 5.951 NM_194317
LYPD6
LY6/PLAUR domain containing 6
chr8_-_37756971 5.309 NM_001002814
NM_025151
RAB11FIP1

RAB11 family interacting protein 1 (class I)

chr1_-_95007139 5.285 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chr9_+_5510544 4.888 NM_025239
PDCD1LG2
programmed cell death 1 ligand 2
chr5_-_141704575 4.841 NM_001127496
NM_030964
SPRY4

sprouty homolog 4 (Drosophila)

chr22_+_41697452 4.830 NM_017590
ZC3H7B
zinc finger CCCH-type containing 7B
chr11_+_19372270 4.618 NM_001111018
NAV2
neuron navigator 2
chr11_+_19734821 4.579 NM_001244963
NM_145117
NM_182964
NAV2


neuron navigator 2


chr17_-_17399494 4.545 NM_001199989
NM_016084
RASD1

RAS, dexamethasone-induced 1

chr11_+_109964086 4.361 NM_033390
ZC3H12C
zinc finger CCCH-type containing 12C
chr10_-_105614952 4.275 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr16_+_86544104 4.118 NM_001451
FOXF1
forkhead box F1
chr12_+_64238511 3.912 NM_020762
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1
chr20_-_47894591 3.910 NM_021035
ZNFX1
zinc finger, NFX1-type containing 1
chr11_+_122526339 3.770 NM_032873
UBASH3B
ubiquitin associated and SH3 domain containing B
chr7_-_22396511 3.715 NM_012294
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr14_+_70078309 3.657 NM_014734
KIAA0247
KIAA0247
chr5_+_10564431 3.649 NM_001164440
ANKRD33B
ankyrin repeat domain 33B
chr17_+_26662547 3.621 NM_021137
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr1_-_205782135 3.579 NM_173854
SLC41A1
solute carrier family 41, member 1
chr5_+_179233351 3.576 NM_001142298
SQSTM1
sequestosome 1
chr10_+_6186758 3.561 NM_001145443
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chrX_+_9432980 3.504 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr5_+_179234002 3.450 NM_001142299
SQSTM1
sequestosome 1
chr12_-_50101192 3.378 NM_175736
NM_198900
FMNL3

formin-like 3

chr10_+_6244839 3.359 NM_004566
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr6_-_137113624 3.319 NM_005923
MAP3K5
mitogen-activated protein kinase kinase kinase 5
chr7_+_28452143 3.258 NM_182898
CREB5
cAMP responsive element binding protein 5
chr7_+_28725597 3.244 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr8_+_123793894 3.214 NM_014943
ZHX2
zinc fingers and homeoboxes 2
chr6_+_36644236 3.188 NM_001220777
NM_078467
CDKN1A

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

chr18_+_55862577 3.171 NM_001144970
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr11_+_69455837 3.142 NM_053056
CCND1
cyclin D1
chr8_+_106331146 3.126 NM_012082
ZFPM2
zinc finger protein, multitype 2
chr5_+_179247841 3.123 NM_003900
SQSTM1
sequestosome 1
chr12_+_121647659 3.122 NM_002560
P2RX4
purinergic receptor P2X, ligand-gated ion channel, 4
chr18_+_55714457 3.062 NM_001144964
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr16_-_11680756 3.011 NM_001136472
NM_001136473
LITAF

lipopolysaccharide-induced TNF factor

chrX_+_9431314 2.974 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr8_+_86089618 2.899 NM_001083588
NM_001951
E2F5

E2F transcription factor 5, p130-binding

chr8_+_86099909 2.890 NM_001083589
E2F5
E2F transcription factor 5, p130-binding
chr16_-_11680146 2.869 NM_004862
LITAF
lipopolysaccharide-induced TNF factor
chr18_+_55888750 2.857 NM_001144966
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr18_+_55711388 2.843 NM_001144967
NM_001243960
NM_015277
NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like


chr18_+_55816546 2.820 NM_001144965
NM_001144968
NM_001144969
NM_001144971
NEDD4L



neural precursor cell expressed, developmentally down-regulated 4-like



chr10_+_28966419 2.818 NM_012342
BAMBI
BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)
chr12_-_9913415 2.815 NM_001781
CD69
CD69 molecule
chr7_+_28338939 2.754 NM_182899
CREB5
cAMP responsive element binding protein 5
chr7_+_28475233 2.714 NM_004904
CREB5
cAMP responsive element binding protein 5
chr21_-_36421586 2.613 NM_001754
RUNX1
runt-related transcription factor 1
chr6_+_36646455 2.611 NM_000389
NM_001220778
CDKN1A

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

chr2_-_106810781 2.581 NM_025076
UXS1
UDP-glucuronate decarboxylase 1
chr2_+_111878450 2.457 NM_001204106
NM_001204107
NM_001204108
NM_001204109
NM_001204110
NM_001204111
NM_001204112
NM_001204113
NM_006538
NM_138621
NM_138622
NM_138623
NM_138624
NM_138625
NM_138626
NM_138627
NM_207002
NM_207003
BCL2L11

















BCL2-like 11 (apoptosis facilitator)

















chr12_-_89918531 2.366 NM_003774
GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chrX_+_68048792 2.351 NM_004429
EFNB1
ephrin-B1
chr7_+_108210188 2.351 NM_012328
DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr16_-_71748697 2.323 NM_015020
PHLPP2
PH domain and leucine rich repeat protein phosphatase 2
chr11_-_57092283 2.230 NM_033396
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr11_+_118307072 2.204 NM_001197104
NM_005933
MLL

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

chr14_+_24630421 2.146 NM_006084
IRF9
interferon regulatory factor 9
chr12_+_45686465 2.140 NM_001142678
ANO6
anoctamin 6
chr1_-_65431826 2.084 NM_002227
JAK1
Janus kinase 1
chr3_-_98620452 2.068 NM_080927
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr1_+_24069855 2.034 NM_003198
TCEB3
transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
chr1_+_101361589 2.032 NM_001144884
NM_133496
SLC30A7

solute carrier family 30 (zinc transporter), member 7

chr14_+_51955854 1.943 NM_001042481
FRMD6
FERM domain containing 6
chr9_-_134585107 1.935 NM_198679
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr17_-_32690180 1.928 NM_002981
CCL1
chemokine (C-C motif) ligand 1
chr6_-_90062610 1.927 NM_016021
UBE2J1
ubiquitin-conjugating enzyme E2, J1, U
chr1_-_55681024 1.911 NM_015306
USP24
ubiquitin specific peptidase 24
chr14_-_45431121 1.900 NM_017658
KLHL28
kelch-like 28 (Drosophila)
chr11_-_1593149 1.884 NM_004420
DUSP8
dual specificity phosphatase 8
chr17_-_28257017 1.876 NM_033389
SSH2
slingshot homolog 2 (Drosophila)
chr9_-_134612924 1.874 NM_005312
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr16_-_87417309 1.834 NM_024735
FBXO31
F-box protein 31
chr19_+_6739697 1.825 NM_004240
TRIP10
thyroid hormone receptor interactor 10
chr2_-_161350304 1.802 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr14_+_52118539 1.788 NM_152330
FRMD6
FERM domain containing 6
chr14_-_73360792 1.762 NM_012074
DPF3
D4, zinc and double PHD fingers, family 3
chr4_+_38665587 1.752 NM_016531
KLF3
Kruppel-like factor 3 (basic)
chr10_+_98592015 1.750 NM_001170765
NM_001170766
LCOR

ligand dependent nuclear receptor corepressor

chr1_-_154578775 1.744 NM_001193495
ADAR
adenosine deaminase, RNA-specific
chr16_+_19125243 1.744 NM_001034841
ITPRIPL2
inositol 1,4,5-trisphosphate receptor interacting protein-like 2
chr10_+_98592658 1.741 NM_032440
LCOR
ligand dependent nuclear receptor corepressor
chr16_+_50776012 1.734 NM_001042412
CYLD
cylindromatosis (turban tumor syndrome)
chr11_+_82612736 1.722 NM_145018
C11orf82
chromosome 11 open reading frame 82
chr7_-_98741681 1.715 NM_001199847
NM_020429
NM_181349
SMURF1


SMAD specific E3 ubiquitin protein ligase 1


chr3_-_15382874 1.714 NM_001018009
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr15_+_65134081 1.711 NM_001195059
NM_025201
PLEKHO2

pleckstrin homology domain containing, family O member 2

chr16_+_50775960 1.703 NM_001042355
NM_015247
CYLD

cylindromatosis (turban tumor syndrome)

chr1_-_204380903 1.696 NM_032833
PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr8_+_38585703 1.672 NM_001146216
TACC1
transforming, acidic coiled-coil containing protein 1
chr10_-_14372807 1.671 NM_018027
FRMD4A
FERM domain containing 4A
chr1_+_213123853 1.663 NM_001136474
NM_001136475
NM_024749
VASH2


vasohibin 2


chr21_-_43373938 1.657 NM_015500
C2CD2
C2 calcium-dependent domain containing 2
chr8_-_122653493 1.652 NM_005328
HAS2
hyaluronan synthase 2
chr16_-_23160509 1.641 NM_020718
USP31
ubiquitin specific peptidase 31
chr3_-_27498244 1.635 NM_003615
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr11_+_35965530 1.622 NM_174902
LDLRAD3
low density lipoprotein receptor class A domain containing 3
chr1_-_154600446 1.611 NM_001025107
ADAR
adenosine deaminase, RNA-specific
chr16_-_1429612 1.600 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr8_+_38644721 1.590 NM_001122824
NM_006283
TACC1

transforming, acidic coiled-coil containing protein 1

chr20_+_6748744 1.585 NM_001200
BMP2
bone morphogenetic protein 2
chr17_-_31203889 1.572 NM_015194
MYO1D
myosin ID
chr4_-_53522756 1.556 NM_001134223
USP46
ubiquitin specific peptidase 46
chr2_-_64881040 1.551 NM_014755
SERTAD2
SERTA domain containing 2
chr15_-_77712436 1.530 NM_024776
PEAK1
NKF3 kinase family member
chr3_-_15374082 1.530 NM_004844
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr11_-_123612324 1.520 NM_003455
ZNF202
zinc finger protein 202
chr8_+_8860313 1.497 NM_153332
ERI1
exoribonuclease 1
chr2_-_235405692 1.491 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr18_+_21572736 1.479 NM_153211
TTC39C
tetratricopeptide repeat domain 39C
chr3_-_66550844 1.467 NM_015541
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr10_-_60027630 1.461 NM_152230
IPMK
inositol polyphosphate multikinase
chr3_-_142166782 1.457 NM_001042604
NM_019001
XRN1

5'-3' exoribonuclease 1

chr9_-_136857285 1.455 NM_001134398
NM_003371
VAV2

vav 2 guanine nucleotide exchange factor

chr12_+_45609767 1.448 NM_001025356
NM_001142679
NM_001204803
ANO6


anoctamin 6


chr3_+_30647901 1.434 NM_001024847
NM_003242
TGFBR2

transforming growth factor, beta receptor II (70/80kDa)

chr22_+_46546498 1.411 NM_001001928
NM_005036
PPARA

peroxisome proliferator-activated receptor alpha

chr2_-_204399906 1.403 NM_203365
NM_213589
RAPH1

Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

chr14_-_89020888 1.401 NM_007039
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr12_-_109251333 1.388 NM_001161330
NM_018984
SSH1

slingshot homolog 1 (Drosophila)

chr4_-_170924911 1.386 NM_001009554
MFAP3L
microfibrillar-associated protein 3-like
chr10_-_120514669 1.384 NM_153810
C10orf46
chromosome 10 open reading frame 46
chr11_+_66886735 1.370 NM_012308
KDM2A
lysine (K)-specific demethylase 2A
chr6_-_167040700 1.368 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr10_+_86088156 1.359 NM_018999
FAM190B
family with sequence similarity 190, member B
chr8_+_17354562 1.351 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr4_-_41216455 1.343 NM_001166050
NM_004307
NM_173075
APBB2


amyloid beta (A4) precursor protein-binding, family B, member 2


chr20_-_4795768 1.339 NM_170774
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr8_+_17396285 1.336 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr7_-_2354050 1.316 NM_013321
SNX8
sorting nexin 8
chr4_+_55095263 1.315 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr9_+_74729510 1.313 NM_001242507
GDA
guanine deaminase
chr3_+_126707380 1.304 NM_032242
PLXNA1
plexin A1
chr12_-_89920038 1.300 NM_001199781
NM_001199782
NM_172240
POC1B-GALNT4

POC1B
POC1B-GALNT4 readthrough

POC1 centriolar protein homolog B (Chlamydomonas)
chr6_-_167275657 1.294 NM_001006932
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr1_+_183605207 1.293 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr14_+_74111577 1.286 NM_001201366
NM_031427
DNAL1

dynein, axonemal, light chain 1

chr5_+_98104998 1.267 NM_001012761
RGMB
RGM domain family, member B
chr8_+_38854431 1.256 NM_003816
ADAM9
ADAM metallopeptidase domain 9
chr3_-_10547267 1.255 NM_001001331
NM_001683
ATP2B2

ATPase, Ca++ transporting, plasma membrane 2

chr5_-_171433876 1.248 NM_012300
NM_033644
NM_033645
FBXW11


F-box and WD repeat domain containing 11


chr2_+_74273449 1.242 NM_144993
TET3
tet methylcytosine dioxygenase 3
chr4_-_15656974 1.238 NM_001193534
NM_001193535
NM_012161
FBXL5


F-box and leucine-rich repeat protein 5


chr2_+_192542860 1.212 NM_001031716
OBFC2A
oligonucleotide/oligosaccharide-binding fold containing 2A
chr18_+_21594349 1.204 NM_001135993
NM_001243425
TTC39C

tetratricopeptide repeat domain 39C

chr21_-_18985224 1.194 NM_001130914
NM_006806
BTG3

BTG family, member 3

chr19_-_344778 1.177 NM_017550
MIER2
mesoderm induction early response 1, family member 2
chr1_+_3614609 1.174 NM_001204192
TP73
tumor protein p73
chr1_-_161102457 1.172 NM_001039711
NM_032998
DEDD

death effector domain containing

chr1_-_161102210 1.162 NM_001039712
DEDD
death effector domain containing
chr2_+_85980600 1.154 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr12_-_26277807 1.154 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr6_-_114384008 1.151 NM_153612
HS3ST5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr1_-_38325224 1.150 NM_005955
MTF1
metal-regulatory transcription factor 1
chr7_+_134576150 1.147 NM_033139
NM_033140
CALD1

caldesmon 1

chr4_-_141677470 1.146 NM_015130
TBC1D9
TBC1 domain family, member 9 (with GRAM domain)
chr1_-_23857711 1.141 NM_004091
E2F2
E2F transcription factor 2
chr21_-_43346780 1.133 NM_199050
C2CD2
C2 calcium-dependent domain containing 2
chr8_-_134584012 1.130 NM_003033
NM_173344
ST3GAL1

ST3 beta-galactoside alpha-2,3-sialyltransferase 1

chr12_+_69864065 1.115 NM_001042555
NM_006654
FRS2

fibroblast growth factor receptor substrate 2

chr1_+_28585959 1.108 NM_031459
SESN2
sestrin 2
chr17_+_8339135 1.106 NM_001025579
NM_030808
NDEL1

nudE nuclear distribution gene E homolog (A. nidulans)-like 1

chr1_-_154580677 1.091 NM_001111
NM_015840
NM_015841
ADAR


adenosine deaminase, RNA-specific


chr6_-_47277646 1.084 NM_014452
TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr4_-_40859081 1.077 NM_001166051
NM_001166052
NM_001166053
NM_001166054
APBB2



amyloid beta (A4) precursor protein-binding, family B, member 2



chr2_-_128100673 1.065 NM_006609
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr2_+_70142152 1.063 NM_001202513
NM_001202514
NM_002357
MXD1


MAX dimerization protein 1


chr14_+_23842017 1.054 NM_172314
NM_022789
IL25

interleukin 25

chr5_-_114880536 1.050 NM_020177
FEM1C
fem-1 homolog c (C. elegans)
chr15_+_89164522 1.050 NM_022767
AEN
apoptosis enhancing nuclease
chr2_+_166428845 1.048 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr12_-_16759531 1.048 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr21_-_36260972 1.036 NM_001001890
NM_001122607
RUNX1

runt-related transcription factor 1

chr20_-_4804067 1.033 NM_014737
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr10_+_115438934 1.030 NM_033340
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr8_+_102504661 1.027 NM_024915
GRHL2
grainyhead-like 2 (Drosophila)
chr8_-_23712297 1.019 NM_003155
STC1
stanniocalcin 1
chr1_+_3569098 1.010 NM_001204184
NM_001204185
NM_001204186
NM_001204187
NM_001204188
NM_005427
TP73





tumor protein p73





chr2_+_29338207 1.008 NM_024692
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr4_-_13546037 1.003 NM_001189
NKX3-2
NK3 homeobox 2
chr12_-_16760935 1.003 NM_001001395
NM_001243609
LMO3

LIM domain only 3 (rhombotin-like 2)

chr15_+_44719578 1.002 NM_016396
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr20_+_46130600 0.996 NM_001174087
NM_001174088
NM_006534
NM_181659
NCOA3



nuclear receptor coactivator 3



chr17_-_5389480 0.995 NM_016041
DERL2
Der1-like domain family, member 2
chr17_-_77005822 0.995 NM_001159772
NM_001159773
NM_138793
CANT1


calcium activated nucleotidase 1


chr17_-_38083762 0.992 NM_139280
ORMDL3
ORM1-like 3 (S. cerevisiae)
chr7_-_92465929 0.991 NM_001145306
CDK6
cyclin-dependent kinase 6
chr4_-_114900802 0.976 NM_024590
ARSJ
arylsulfatase family, member J
chr17_-_4167028 0.976 NM_016376
NM_020740
ANKFY1

ankyrin repeat and FYVE domain containing 1

chr1_-_113250022 0.970 NM_001042678
NM_175744
RHOC

ras homolog gene family, member C

chr14_+_73603140 0.960 NM_000021
NM_007318
PSEN1

presenilin 1

chr15_-_41408329 0.948 NM_017553
INO80
INO80 homolog (S. cerevisiae)
chr5_-_9546157 0.946 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.38 1.93e-08 GO:0050794 regulation of cellular process
2.07 4.76e-08 GO:0007399 nervous system development
1.79 4.90e-08 GO:0048522 positive regulation of cellular process
2.01 5.69e-08 GO:0023051 regulation of signaling
2.07 1.67e-07 GO:0009966 regulation of signal transduction
1.34 1.94e-07 GO:0050789 regulation of biological process
2.54 2.88e-07 GO:0010557 positive regulation of macromolecule biosynthetic process
2.42 4.27e-07 GO:0031328 positive regulation of cellular biosynthetic process
1.31 6.75e-07 GO:0065007 biological regulation
1.68 7.85e-07 GO:0048518 positive regulation of biological process
2.38 8.33e-07 GO:0009891 positive regulation of biosynthetic process
2.66 9.46e-07 GO:0045893 positive regulation of transcription, DNA-dependent
1.65 1.37e-06 GO:0048731 system development
2.55 1.69e-06 GO:0010628 positive regulation of gene expression
2.53 3.47e-06 GO:0051254 positive regulation of RNA metabolic process
2.41 4.36e-06 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.38 4.70e-06 GO:0051173 positive regulation of nitrogen compound metabolic process
1.55 8.01e-06 GO:0007275 multicellular organismal development
2.05 1.52e-05 GO:0010604 positive regulation of macromolecule metabolic process
1.72 1.60e-05 GO:0048523 negative regulation of cellular process
1.99 1.94e-05 GO:0009893 positive regulation of metabolic process
2.02 2.11e-05 GO:0031325 positive regulation of cellular metabolic process
1.54 2.13e-05 GO:0060255 regulation of macromolecule metabolic process
2.44 3.25e-05 GO:0007167 enzyme linked receptor protein signaling pathway
1.49 3.83e-05 GO:0032502 developmental process
1.55 4.05e-05 GO:0048856 anatomical structure development
1.51 4.40e-05 GO:0080090 regulation of primary metabolic process
2.16 6.16e-05 GO:0022008 neurogenesis
1.50 6.46e-05 GO:0031323 regulation of cellular metabolic process
1.74 9.41e-05 GO:0048583 regulation of response to stimulus
2.16 9.63e-05 GO:0006351 transcription, DNA-dependent
1.45 1.41e-04 GO:0019222 regulation of metabolic process
1.63 1.71e-04 GO:0048519 negative regulation of biological process
1.68 2.07e-04 GO:0030154 cell differentiation
2.85 2.24e-04 GO:0051056 regulation of small GTPase mediated signal transduction
7.29 3.73e-04 GO:0000186 activation of MAPKK activity
1.57 6.18e-04 GO:0010468 regulation of gene expression
1.64 7.75e-04 GO:0048869 cellular developmental process
2.44 1.11e-03 GO:0043065 positive regulation of apoptosis
2.43 1.30e-03 GO:0043068 positive regulation of programmed cell death
2.05 1.54e-03 GO:0048699 generation of neurons
2.48 1.63e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.39 1.96e-03 GO:0010942 positive regulation of cell death
1.95 2.74e-03 GO:0032774 RNA biosynthetic process
1.42 2.88e-03 GO:0023052 signaling
1.78 3.07e-03 GO:0035556 intracellular signal transduction
2.35 3.85e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.37 3.99e-03 GO:0044260 cellular macromolecule metabolic process
1.43 5.15e-03 GO:0007165 signal transduction
2.56 5.23e-03 GO:0007264 small GTPase mediated signal transduction
1.53 5.93e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.63 6.09e-03 GO:0006464 protein modification process
1.55 7.92e-03 GO:0051252 regulation of RNA metabolic process
1.49 9.49e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.51 1.17e-02 GO:0010556 regulation of macromolecule biosynthetic process
3.04 1.21e-02 GO:0048011 nerve growth factor receptor signaling pathway
2.29 1.32e-02 GO:0000904 cell morphogenesis involved in differentiation
1.87 1.41e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.58 1.56e-02 GO:0043412 macromolecule modification
2.17 1.68e-02 GO:0048666 neuron development
1.84 1.79e-02 GO:0006793 phosphorus metabolic process
1.84 1.79e-02 GO:0006796 phosphate metabolic process
2.39 2.00e-02 GO:0007243 intracellular protein kinase cascade
2.39 2.00e-02 GO:0023014 signal transduction via phosphorylation event
2.04 2.02e-02 GO:0030182 neuron differentiation
3.75 2.05e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
3.72 2.27e-02 GO:0022604 regulation of cell morphogenesis
1.53 2.31e-02 GO:0006355 regulation of transcription, DNA-dependent
1.46 2.37e-02 GO:0051171 regulation of nitrogen compound metabolic process
2.04 2.57e-02 GO:0045595 regulation of cell differentiation
1.34 3.51e-02 GO:0051716 cellular response to stimulus
1.79 3.64e-02 GO:0010941 regulation of cell death
6.59 3.87e-02 GO:0051318 G1 phase
2.57 4.70e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.84 4.73e-02 GO:0048468 cell development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.33 6.50e-05 GO:0005634 nucleus
1.15 1.68e-04 GO:0005622 intracellular
1.14 1.38e-03 GO:0044424 intracellular part
3.12 5.65e-03 GO:0030424 axon
2.31 7.83e-03 GO:0043005 neuron projection
1.15 2.15e-02 GO:0043226 organelle
1.15 2.55e-02 GO:0043229 intracellular organelle
1.62 2.60e-02 GO:0005654 nucleoplasm

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.32 3.99e-07 GO:0005515 protein binding
2.10 6.13e-06 GO:0001071 nucleic acid binding transcription factor activity
2.10 6.13e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
2.24 2.00e-05 GO:0019899 enzyme binding
2.02 3.51e-05 GO:0030528 transcription regulator activity
2.89 3.34e-04 GO:0005083 small GTPase regulator activity
1.14 3.88e-04 GO:0005488 binding
2.27 3.14e-03 GO:0060589 nucleoside-triphosphatase regulator activity
2.27 4.55e-03 GO:0030695 GTPase regulator activity
9.63 8.59e-03 GO:0004709 MAP kinase kinase kinase activity
2.76 1.07e-02 GO:0019900 kinase binding
2.93 1.14e-02 GO:0019901 protein kinase binding
15.24 2.69e-02 GO:0030332 cyclin binding
2.45 2.90e-02 GO:0008134 transcription factor binding
2.38 3.35e-02 GO:0016563 transcription activator activity
13.55 4.71e-02 GO:0051019 mitogen-activated protein kinase binding