Motif ID: AAGGCAC

Z-value: 1.159


Mature miRNA associated with seed AAGGCAC:

NamemiRBase Accession
hsa-miR-124 MIMAT0000422
hsa-miR-506 MIMAT0002878



Activity profile for motif AAGGCAC.

activity profile for motif AAGGCAC


Sorted Z-values histogram for motif AAGGCAC

Sorted Z-values for motif AAGGCAC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAGGCAC

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_143266283 3.393 NM_006734
 HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr6_-_154831704 3.294 NM_173515
 CNKSR3
CNKSR family member 3
chr4_-_120549115 3.256 NM_033437
 PDE5A
phosphodiesterase 5A, cGMP-specific
chr5_-_131826426 2.564 NM_002198
 IRF1
interferon regulatory factor 1
chr11_-_72380107 2.412 NM_001146209
 PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr11_-_72353435 2.381 NM_001143839
NM_001243784
 PDE2A

phosphodiesterase 2A, cGMP-stimulated

chr9_+_115913227 2.305 NM_001860
 SLC31A2
solute carrier family 31 (copper transporters), member 2
chr4_-_120549827 2.289 NM_001083
 PDE5A
phosphodiesterase 5A, cGMP-specific
chr16_-_11680756 2.189 NM_001136472
NM_001136473
 LITAF

lipopolysaccharide-induced TNF factor

chr7_-_25019625 2.156 NM_015550
NM_145320
NM_145321
NM_145322
 OSBPL3



oxysterol binding protein-like 3



chr16_-_11680146 2.088 NM_004862
 LITAF
lipopolysaccharide-induced TNF factor
chr11_-_72385411 2.055 NM_002599
 PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr6_+_37137882 2.005 NM_001243186
NM_002648
 PIM1

pim-1 oncogene

chr11_-_128457452 1.998 NM_001143820
 ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr5_+_127419407 1.996 NM_001046
 SLC12A2
solute carrier family 12 (sodium/potassium/chloride transporters), member 2
chr11_-_128392061 1.861 NM_001162422
NM_005238
 ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chr6_+_126111782 1.850 NM_001122842
NM_001199621
NM_181782
 NCOA7


nuclear receptor coactivator 7


chr4_-_120548329 1.849 NM_033430
 PDE5A
phosphodiesterase 5A, cGMP-specific
chr5_-_179780314 1.843 NM_005110
 GFPT2
glutamine-fructose-6-phosphate transaminase 2
chr8_-_37756971 1.829 NM_001002814
NM_025151
 RAB11FIP1

RAB11 family interacting protein 1 (class I)


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 46 entries
enrichment   p-value GO term description
3.27 1.93e-02 GO:0031098 stress-activated protein kinase signaling cascade
2.95 9.17e-05 GO:0048011 nerve growth factor receptor signaling pathway
2.38 8.44e-05 GO:0007409 axonogenesis
2.30 1.64e-04 GO:0048812 neuron projection morphogenesis
2.29 2.51e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
2.28 8.47e-03 GO:0007411 axon guidance
2.18 3.80e-04 GO:0048858 cell projection morphogenesis
2.16 5.00e-04 GO:0032990 cell part morphogenesis
2.11 1.80e-03 GO:0000904 cell morphogenesis involved in differentiation
2.09 3.05e-03 GO:0031175 neuron projection development
2.08 9.13e-03 GO:0061024 membrane organization
2.07 4.69e-02 GO:0007264 small GTPase mediated signal transduction
2.04 1.85e-02 GO:0016044 cellular membrane organization
2.03 1.69e-03 GO:0048666 neuron development
2.03 4.19e-02 GO:0007243 intracellular protein kinase cascade
2.03 4.19e-02 GO:0023014 signal transduction via phosphorylation event
2.02 1.10e-03 GO:0000902 cell morphogenesis
1.99 8.74e-04 GO:0030030 cell projection organization
1.99 1.22e-03 GO:0032989 cellular component morphogenesis
1.96 2.14e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
2.38 3.55e-02 GO:0030425 dendrite
2.01 8.26e-03 GO:0045202 synapse
1.89 1.68e-03 GO:0030054 cell junction
1.51 6.59e-05 GO:0005829 cytosol
1.37 2.29e-02 GO:0044459 plasma membrane part
1.22 2.34e-03 GO:0044444 cytoplasmic part
1.17 4.75e-04 GO:0005737 cytoplasm
1.17 3.70e-03 GO:0016020 membrane
1.11 2.81e-03 GO:0005622 intracellular
1.11 4.55e-03 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
3.21 3.07e-02 GO:0005088 Ras guanyl-nucleotide exchange factor activity
2.11 1.90e-02 GO:0003779 actin binding
1.89 6.79e-03 GO:0008092 cytoskeletal protein binding
1.71 1.04e-02 GO:0016301 kinase activity
1.39 4.46e-02 GO:0032553 ribonucleotide binding
1.39 4.46e-02 GO:0032555 purine ribonucleotide binding
1.39 4.99e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.25 8.44e-07 GO:0005515 protein binding
1.10 1.06e-02 GO:0005488 binding