Motif ID: AAGUGCU

Z-value: 1.459


Mature miRNA associated with seed AAGUGCU:

NamemiRBase Accession
hsa-miR-302a MIMAT0000684
hsa-miR-302b MIMAT0000715
hsa-miR-302c MIMAT0000717
hsa-miR-302d MIMAT0000718
hsa-miR-302e MIMAT0005931
hsa-miR-372 MIMAT0000724
hsa-miR-373 MIMAT0000726
hsa-miR-520a-3p MIMAT0002834
hsa-miR-520b MIMAT0002843
hsa-miR-520c-3p MIMAT0002846
hsa-miR-520d-3p MIMAT0002856
hsa-miR-520e MIMAT0002825



Activity profile for motif AAGUGCU.

activity profile for motif AAGUGCU


Sorted Z-values histogram for motif AAGUGCU

Sorted Z-values for motif AAGUGCU



Network of associatons between targets according to the STRING database.



First level regulatory network of AAGUGCU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_126237566 8.397 NM_024582
FAT4
FAT tumor suppressor homolog 4 (Drosophila)
chr1_+_61542928 7.017 NM_001145511
NFIA
nuclear factor I/A
chr2_-_190445521 6.991 NM_014585
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr1_+_61547625 6.834 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr1_+_61547388 6.353 NM_001145512
NFIA
nuclear factor I/A
chr4_+_156588811 6.039 NM_001130684
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr12_+_27397077 5.688 NM_015000
STK38L
serine/threonine kinase 38 like
chr10_-_81205091 5.665 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr9_-_14398981 5.431 NM_001190738
NFIB
nuclear factor I/B
chr18_+_42260774 5.379 NM_015559
SETBP1
SET binding protein 1
chr9_-_14314036 4.972 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr9_-_134151905 4.751 NM_033387
FAM78A
family with sequence similarity 78, member A
chr3_+_43328001 4.625 NM_001100594
NM_017719
SNRK

SNF related kinase

chr7_+_1097140 4.574 NM_138445
GPR146
G protein-coupled receptor 146
chr3_+_20081523 4.401 NM_003884
KAT2B
K(lysine) acetyltransferase 2B
chr10_+_112631552 4.340 NM_001199492
NM_014456
NM_145341
PDCD4


programmed cell death 4 (neoplastic transformation inhibitor)


chr12_+_32654976 4.332 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr9_-_107690526 4.310 NM_005502
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr6_+_11538486 4.118 NM_001100829
TMEM170B
transmembrane protein 170B
chr4_+_6271558 3.966 NM_001145853
NM_006005
WFS1

Wolfram syndrome 1 (wolframin)


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 23 entries
enrichment   p-value GO term description
2.20 4.00e-03 GO:0006468 protein phosphorylation
2.16 4.59e-02 GO:0045893 positive regulation of transcription, DNA-dependent
2.11 4.14e-02 GO:0010628 positive regulation of gene expression
1.99 3.34e-02 GO:0016310 phosphorylation
1.96 1.24e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.95 4.22e-02 GO:0006351 transcription, DNA-dependent
1.72 2.91e-02 GO:0007399 nervous system development
1.63 3.23e-02 GO:0006464 protein modification process
1.62 6.82e-03 GO:0006355 regulation of transcription, DNA-dependent
1.61 2.30e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.61 5.23e-03 GO:0051252 regulation of RNA metabolic process
1.58 4.00e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.56 3.15e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.55 8.03e-03 GO:0010468 regulation of gene expression
1.53 6.90e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.52 1.57e-02 GO:0009889 regulation of biosynthetic process
1.52 1.68e-02 GO:0031326 regulation of cellular biosynthetic process
1.50 1.72e-03 GO:0060255 regulation of macromolecule metabolic process
1.46 3.91e-03 GO:0031323 regulation of cellular metabolic process
1.46 5.39e-03 GO:0080090 regulation of primary metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
4.04 4.76e-02 GO:0016585 chromatin remodeling complex
1.68 2.79e-02 GO:0005654 nucleoplasm
1.67 1.41e-03 GO:0031981 nuclear lumen
1.53 1.59e-02 GO:0044428 nuclear part
1.40 5.32e-06 GO:0005634 nucleus
1.19 2.05e-02 GO:0043231 intracellular membrane-bounded organelle
1.18 6.33e-03 GO:0043229 intracellular organelle
1.18 7.55e-03 GO:0043226 organelle
1.18 2.24e-02 GO:0043227 membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
6.80 5.13e-04 GO:0004879 ligand-dependent nuclear receptor activity
6.48 2.58e-03 GO:0003707 steroid hormone receptor activity
5.98 4.45e-02 GO:0042826 histone deacetylase binding
2.72 1.65e-04 GO:0004674 protein serine/threonine kinase activity
2.28 1.34e-03 GO:0004672 protein kinase activity
2.13 2.03e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
2.10 9.29e-05 GO:0001071 nucleic acid binding transcription factor activity
2.10 9.29e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
2.06 1.19e-02 GO:0043565 sequence-specific DNA binding
1.98 1.04e-02 GO:0016301 kinase activity
1.84 2.93e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.74 2.60e-05 GO:0008270 zinc ion binding
1.63 1.91e-04 GO:0046914 transition metal ion binding
1.59 4.53e-08 GO:0046872 metal ion binding
1.59 1.08e-03 GO:0003677 DNA binding
1.58 6.75e-08 GO:0043167 ion binding
1.57 1.08e-07 GO:0043169 cation binding
1.44 4.37e-03 GO:0003676 nucleic acid binding
1.14 1.92e-03 GO:0005488 binding