Motif ID: AAUCUCA

Z-value: 0.238


Mature miRNA associated with seed AAUCUCA:

NamemiRBase Accession
hsa-miR-216a MIMAT0000273



Activity profile for motif AAUCUCA.

activity profile for motif AAUCUCA


Sorted Z-values histogram for motif AAUCUCA

Sorted Z-values for motif AAUCUCA



Network of associatons between targets according to the STRING database.



First level regulatory network of AAUCUCA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_170075449 0.137 NM_001145098
NM_005414
SKIL

SKI-like oncogene

chr12_-_95044205 0.091 NM_020698
TMCC3
transmembrane and coiled-coil domain family 3
chrX_-_20284708 0.091 NM_004586
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr4_+_89299874 0.090 NM_001165136
NM_017912
HERC6

hect domain and RLD 6

chr6_+_147829784 0.090 NM_001030060
SAMD5
sterile alpha motif domain containing 5
chr1_-_53793743 0.085 NM_001018054
NM_004631
NM_017522
NM_033300
LRP8



low density lipoprotein receptor-related protein 8, apolipoprotein e receptor



chr10_-_97321094 0.080 NM_015385
NM_024991
SORBS1

sorbin and SH3 domain containing 1

chr18_-_22932109 0.080 NM_015461
ZNF521
zinc finger protein 521
chr3_+_170077410 0.077 NM_001145097
NM_001248008
SKIL

SKI-like oncogene

chr1_-_151882360 0.076 NM_053055
THEM4
thioesterase superfamily member 4
chr6_+_110501591 0.075 NM_015891
CDC40
cell division cycle 40 homolog (S. cerevisiae)
chr2_-_151344145 0.074 NM_005168
RND3
Rho family GTPase 3
chr11_+_111848008 0.073 NM_033425
DIXDC1
DIX domain containing 1
chr12_-_50236868 0.070 NM_181708
BCDIN3D
BCDIN3 domain containing
chr4_+_175204827 0.070 NM_001040157
CEP44
centrosomal protein 44kDa
chr9_+_4662285 0.070 NM_203453
PPAPDC2
phosphatidic acid phosphatase type 2 domain containing 2
chr3_-_125094003 0.069 NM_021964
ZNF148
zinc finger protein 148
chr7_+_12250818 0.068 NM_001134232
NM_018374
TMEM106B

transmembrane protein 106B

chr5_+_149151502 0.066 NM_001172699
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr5_+_149109814 0.065 NM_001172698
NM_133263
PPARGC1B

peroxisome proliferator-activated receptor gamma, coactivator 1 beta

chr10_-_97200895 0.063 NM_001034954
NM_001034955
NM_001034956
NM_001034957
NM_006434
SORBS1




sorbin and SH3 domain containing 1




chr18_+_59854514 0.062 NM_020854
KIAA1468
KIAA1468
chr6_+_42788793 0.061 NM_015349
KIAA0240
KIAA0240
chr6_-_138428477 0.059 NM_022121
PERP
PERP, TP53 apoptosis effector
chr3_+_45927995 0.058 NM_006641
NM_031200
CCR9

chemokine (C-C motif) receptor 9

chr7_-_105319608 0.057 NM_138495
ATXN7L1
ataxin 7-like 1
chr1_-_220263150 0.057 NM_006085
BPNT1
3'(2'), 5'-bisphosphate nucleotidase 1
chr2_+_148778573 0.056 NM_018328
MBD5
methyl-CpG binding domain protein 5
chr7_-_91509979 0.056 NM_006980
MTERF
mitochondrial transcription termination factor
chr10_-_95462311 0.055 NM_145246
FRA10AC1
fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1
chr1_-_205782135 0.055 NM_173854
SLC41A1
solute carrier family 41, member 1
chr5_+_130506635 0.050 NM_181705
LYRM7
Lyrm7 homolog (mouse)
chr7_+_35840595 0.050 NM_001011553
NM_001242956
NM_001788
SEPT7


septin 7


chr13_-_21476895 0.049 NM_022459
XPO4
exportin 4
chr3_-_160117314 0.048 NM_001190241
NM_020800
IFT80

intraflagellar transport 80 homolog (Chlamydomonas)

chr4_+_99916787 0.047 NM_015143
METAP1
methionyl aminopeptidase 1
chr4_-_88141614 0.047 NM_020803
KLHL8
kelch-like 8 (Drosophila)
chr5_+_139493689 0.046 NM_005859
PURA
purine-rich element binding protein A
chr3_-_160101443 0.045 NM_001190242
IFT80
intraflagellar transport 80 homolog (Chlamydomonas)
chr2_+_109204745 0.044 NM_004987
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_+_109204904 0.044 NM_001193488
LIMS1
LIM and senescent cell antigen-like domains 1
chr15_+_91643429 0.044 NM_014848
SV2B
synaptic vesicle glycoprotein 2B
chr8_-_87520981 0.043 NM_016033
FAM82B
family with sequence similarity 82, member B
chr3_+_108308336 0.043 NM_014648
DZIP3
DAZ interacting protein 3, zinc finger
chr12_+_123237302 0.042 NM_003677
DENR
density-regulated protein
chrX_-_109683457 0.042 NM_001171689
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr6_+_7590405 0.042 NM_152551
SNRNP48
small nuclear ribonucleoprotein 48kDa (U11/U12)
chrX_-_109561314 0.042 NM_001025580
NM_015365
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr8_-_110342107 0.041 NM_001128211
NUDCD1
NudC domain containing 1
chr15_-_43662107 0.041 NM_152455
ZSCAN29
zinc finger and SCAN domain containing 29
chr3_+_39851028 0.041 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr11_+_74459900 0.041 NM_001098638
RNF169
ring finger protein 169
chr8_-_110346272 0.041 NM_032869
NUDCD1
NudC domain containing 1
chr6_-_82462374 0.040 NM_017633
FAM46A
family with sequence similarity 46, member A
chr2_+_109237679 0.040 NM_001193484
LIMS1
LIM and senescent cell antigen-like domains 1
chr12_-_31743822 0.039 NM_144973
DENND5B
DENN/MADD domain containing 5B
chr2_+_109150807 0.039 NM_001193483
LIMS1
LIM and senescent cell antigen-like domains 1
chr16_-_57520326 0.039 NM_018110
DOK4
docking protein 4
chr7_-_115670828 0.039 NM_001018058
NM_012252
TFEC

transcription factor EC

chr19_+_54024176 0.039 NM_018555
ZNF331
zinc finger protein 331
chr2_+_109271267 0.039 NM_001193485
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_+_178257371 0.039 NM_003659
AGPS
alkylglycerone phosphate synthase
chrX_+_119738542 0.038 NM_001137554
MCTS1
malignant T cell amplified sequence 1
chr1_+_236687026 0.037 NM_201544
LGALS8
lectin, galactoside-binding, soluble, 8
chr11_+_111807857 0.037 NM_001037954
DIXDC1
DIX domain containing 1
chr12_-_89919182 0.037 NM_001199777
POC1B
POC1 centriolar protein homolog B (Chlamydomonas)
chr13_-_31040035 0.036 NM_002128
HMGB1
high mobility group box 1
chr4_+_81952118 0.035 NM_001201
BMP3
bone morphogenetic protein 3
chr17_-_7382943 0.035 NM_001128833
ZBTB4
zinc finger and BTB domain containing 4
chr3_-_121553907 0.034 NM_001023570
NM_001023571
IQCB1

IQ motif containing B1

chr12_-_10022457 0.034 NM_005127
CLEC2B
C-type lectin domain family 2, member B
chr19_+_54041332 0.034 NM_001079906
NM_001253798
NM_001253799
ZNF331


zinc finger protein 331


chr8_+_1922030 0.034 NM_014867
KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr5_-_137549029 0.034 NM_004661
CDC23
cell division cycle 23 homolog (S. cerevisiae)
chrX_+_119737743 0.034 NM_014060
MCTS1
malignant T cell amplified sequence 1
chr2_+_109223600 0.033 NM_001193482
LIMS1
LIM and senescent cell antigen-like domains 1
chr10_+_11206928 0.033 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr1_+_236686738 0.032 NM_006499
NM_201543
LGALS8

lectin, galactoside-binding, soluble, 8

chr3_+_101498028 0.032 NM_145037
FAM55C
family with sequence similarity 55, member C
chr1_+_236681513 0.032 NM_201545
LGALS8
lectin, galactoside-binding, soluble, 8
chr20_+_54933982 0.032 NM_080821
FAM210B
family with sequence similarity 210, member B
chr17_+_64298844 0.031 NM_002737
PRKCA
protein kinase C, alpha
chr15_+_65914269 0.031 NM_004727
SLC24A1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr17_-_47755340 0.030 NM_001007226
NM_001007227
NM_001007228
NM_001007229
NM_001007230
NM_003563
SPOP





speckle-type POZ protein





chr17_+_59477169 0.030 NM_005994
TBX2
T-box 2
chr2_+_175260455 0.030 NM_001193528
NM_024583
SCRN3

secernin 3

chr1_+_24882565 0.029 NM_001010980
C1orf130
chromosome 1 open reading frame 130
chr9_-_14693459 0.029 NM_178566
ZDHHC21
zinc finger, DHHC-type containing 21
chr17_+_53342320 0.029 NM_002126
HLF
hepatic leukemia factor
chr4_-_121993568 0.029 NM_024574
NDNF
neuron-derived neurotrophic factor
chr6_-_134373618 0.029 NM_145176
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr3_+_142342265 0.029 NM_002670
PLS1
plastin 1
chr19_+_52901101 0.028 NM_032423
ZNF528
zinc finger protein 528
chr16_+_8768403 0.028 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr8_+_67341244 0.028 NM_015169
RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr1_-_67896098 0.027 NM_001018067
NM_001018068
NM_001018069
NM_015640
SERBP1



SERPINE1 mRNA binding protein 1



chr11_-_64764388 0.027 NM_138456
BATF2
basic leucine zipper transcription factor, ATF-like 2
chr5_+_68788387 0.027 NM_001205254
OCLN
occludin
chr20_+_18122867 0.027 NM_020536
CSRP2BP
CSRP2 binding protein
chr1_-_155532322 0.027 NM_018489
ASH1L
ash1 (absent, small, or homeotic)-like (Drosophila)
chr2_+_139259349 0.027 NM_001001664
SPOPL
speckle-type POZ protein-like
chr17_+_48046561 0.027 NM_138281
DLX4
distal-less homeobox 4
chr8_-_146126776 0.027 NM_001109689
NM_021061
ZNF250

zinc finger protein 250

chr2_+_85980600 0.027 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr20_+_43514340 0.026 NM_003404
NM_139323
YWHAB

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

chr18_-_61034350 0.026 NM_002035
KDSR
3-ketodihydrosphingosine reductase
chr3_+_142375738 0.026 NM_001172312
PLS1
plastin 1
chr1_-_52456292 0.026 NM_002867
RAB3B
RAB3B, member RAS oncogene family
chr5_-_58334936 0.026 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr16_+_8814567 0.026 NM_001127448
ABAT
4-aminobutyrate aminotransferase
chr4_-_85887543 0.026 NM_014991
WDFY3
WD repeat and FYVE domain containing 3
chr14_+_102228134 0.025 NM_001161725
NM_001161726
PPP2R5C

protein phosphatase 2, regulatory subunit B', gamma

chr10_+_11047253 0.025 NM_001025077
CELF2
CUGBP, Elav-like family member 2
chr6_-_80247103 0.025 NM_001122769
NM_181714
LCA5

Leber congenital amaurosis 5

chr10_+_46222647 0.025 NM_001169106
NM_001169107
NM_015262
FAM21C


family with sequence similarity 21, member C


chr10_+_11059854 0.025 NM_006561
CELF2
CUGBP, Elav-like family member 2
chr11_-_132812870 0.025 NM_002545
OPCML
opioid binding protein/cell adhesion molecule-like
chr5_-_59189620 0.024 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr19_+_54058493 0.024 NM_001079907
ZNF331
zinc finger protein 331
chr8_-_144923019 0.024 NM_178564
NRBP2
nuclear receptor binding protein 2
chr16_+_8806825 0.024 NM_000663
ABAT
4-aminobutyrate aminotransferase
chr2_+_95831176 0.024 NM_001017396
NM_021088
ZNF2

zinc finger protein 2

chr10_+_51827654 0.024 NM_001005751
FAM21C
FAM21A
family with sequence similarity 21, member C
family with sequence similarity 21, member A
chr3_+_142315205 0.024 NM_001145319
PLS1
plastin 1
chr10_-_104473957 0.024 NM_004311
ARL3
ADP-ribosylation factor-like 3
chr1_-_89738477 0.024 NM_001134486
NM_052942
GBP5

guanylate binding protein 5

chr5_-_59783885 0.024 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_58295758 0.023 NM_001197223
PDE4D
phosphodiesterase 4D, cAMP-specific
chr11_+_108093558 0.023 NM_000051
ATM
ataxia telangiectasia mutated
chr3_+_101498285 0.023 NM_001134456
FAM55C
family with sequence similarity 55, member C
chr22_+_21213248 0.023 NM_004782
SNAP29
synaptosomal-associated protein, 29kDa
chr9_-_15510209 0.023 NM_021144
PSIP1
PC4 and SFRS1 interacting protein 1
chr3_-_121264780 0.023 NM_199420
POLQ
polymerase (DNA directed), theta
chr5_-_58652671 0.023 NM_001197219
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_58571916 0.022 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr11_+_111944967 0.022 NM_001082969
NM_001082970
NM_018195
C11orf57


chromosome 11 open reading frame 57


chr2_-_203776948 0.022 NM_018256
WDR12
WD repeat domain 12
chr15_-_33360084 0.022 NM_001103184
FMN1
formin 1
chr6_+_30951484 0.021 NM_001010909
MUC21
mucin 21, cell surface associated
chr4_-_113437327 0.021 NM_024019
NEUROG2
neurogenin 2
chr16_-_19729417 0.021 NM_001012991
C16orf88
chromosome 16 open reading frame 88
chr11_+_96123120 0.021 NM_003772
JRKL
jerky homolog-like (mouse)
chr11_-_130184459 0.021 NM_014155
ZBTB44
zinc finger and BTB domain containing 44
chr5_+_122424840 0.021 NM_001136239
PRDM6
PR domain containing 6
chr5_+_68800003 0.021 NM_001205255
OCLN
occludin
chr1_-_109506016 0.021 NM_001048210
NM_015127
CLCC1

AKNAD1
chloride channel CLIC-like 1

AKNA domain containing 1
chr17_+_37793332 0.021 NM_001165937
NM_001165938
NM_006804
STARD3


StAR-related lipid transfer (START) domain containing 3


chr12_+_106994914 0.020 NM_001206691
RFX4
regulatory factor X, 4 (influences HLA class II expression)
chr17_-_7387513 0.020 NM_020899
ZBTB4
zinc finger and BTB domain containing 4
chr17_+_46018888 0.020 NM_018129
PNPO
pyridoxamine 5'-phosphate oxidase
chr1_-_236030219 0.019 NM_000081
LYST
lysosomal trafficking regulator
chr16_+_69599868 0.019 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr2_+_135676387 0.019 NM_001241
NM_058241
CCNT2

cyclin T2

chr3_+_196295708 0.019 NM_001105573
FBXO45
F-box protein 45
chr22_-_46933066 0.019 NM_014246
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr9_+_125133228 0.018 NM_000962
NM_080591
PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr17_-_26941178 0.018 NM_001174103
SGK494
uncharacterized serine/threonine-protein kinase SgK494
chr11_-_69490093 0.018 NM_153451
ORAOV1
oral cancer overexpressed 1
chrX_-_7895424 0.017 NM_004650
PNPLA4
patatin-like phospholipase domain containing 4
chr17_-_16118789 0.017 NM_006311
NCOR1
nuclear receptor corepressor 1
chr3_-_69129502 0.017 NM_003968
NM_198195
UBA3

ubiquitin-like modifier activating enzyme 3

chr5_-_10761344 0.016 NM_004394
DAP
death-associated protein
chr11_-_133402227 0.016 NM_001012393
OPCML
opioid binding protein/cell adhesion molecule-like
chr1_-_67520028 0.016 NM_015139
SLC35D1
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
chr1_-_144931967 0.016 NM_001002811
PDE4DIP
phosphodiesterase 4D interacting protein
chr2_+_26987122 0.016 NM_017877
CENPA
C2orf18
centromere protein A
chromosome 2 open reading frame 18
chr5_-_59064437 0.015 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr6_-_107780682 0.015 NM_020381
PDSS2
prenyl (decaprenyl) diphosphate synthase, subunit 2
chr10_+_112404104 0.015 NM_001134363
RBM20
RNA binding motif protein 20
chrX_-_7895764 0.015 NM_001142389
NM_001172672
PNPLA4

patatin-like phospholipase domain containing 4

chr15_-_83953465 0.015 NM_001717
BNC1
basonuclin 1
chr16_-_10276115 0.014 NM_001134407
GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr16_-_10276610 0.014 NM_000833
GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr15_+_91643181 0.014 NM_001167580
SV2B
synaptic vesicle glycoprotein 2B
chr8_-_57233240 0.014 NM_138969
SDR16C5
short chain dehydrogenase/reductase family 16C, member 5
chr9_+_115513050 0.014 NM_001012994
SNX30
sorting nexin family member 30
chr13_-_100624162 0.013 NM_033132
ZIC5
Zic family member 5
chr15_+_63481713 0.013 NM_016530
RAB8B
RAB8B, member RAS oncogene family
chr4_+_145567147 0.013 NM_022475
HHIP
hedgehog interacting protein
chr2_+_113885137 0.013 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr5_-_34043234 0.013 NM_030945
NM_181435
C1QTNF3

C1q and tumor necrosis factor related protein 3

chr5_-_58882274 0.013 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_+_40566341 0.013 NM_001098414
NM_198484
ZNF621

zinc finger protein 621

chr14_-_35183722 0.012 NM_001243645
NM_138638
CFL2

cofilin 2 (muscle)

chr15_-_42840992 0.012 NM_153260
LRRC57
leucine rich repeat containing 57
chr3_+_141043054 0.012 NM_001080412
ZBTB38
zinc finger and BTB domain containing 38
chr15_+_22833394 0.012 NM_001102610
NM_052903
TUBGCP5

tubulin, gamma complex associated protein 5

chr20_+_11898536 0.012 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr4_+_76649826 0.012 NM_003715
USO1
USO1 vesicle docking protein homolog (yeast)
chr12_+_27863705 0.012 NM_001190864
NM_021821
MRPS35

mitochondrial ribosomal protein S35

chr3_-_142166782 0.012 NM_001042604
NM_019001
XRN1

5'-3' exoribonuclease 1

chr3_+_42642105 0.012 NM_005385
NKTR
natural killer-tumor recognition sequence
chr16_-_4292052 0.011 NM_001098814
SRL
sarcalumenin
chr12_-_57030083 0.011 NM_013449
BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chr17_-_29641094 0.011 NM_006495
EVI2B
ecotropic viral integration site 2B
chr17_-_73975507 0.011 NM_001185039
NM_004035
NM_007292
ACOX1


acyl-CoA oxidase 1, palmitoyl


chr5_+_68788118 0.010 NM_002538
OCLN
occludin
chr6_-_24666818 0.010 NM_016614
TDP2
tyrosyl-DNA phosphodiesterase 2
chr1_-_68915631 0.010 NM_000329
RPE65
retinal pigment epithelium-specific protein 65kDa
chr1_+_78956727 0.010 NM_000959
NM_001039585
PTGFR

prostaglandin F receptor (FP)


Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.47 1.92e-03 GO:0005634 nucleus
1.20 1.30e-02 GO:0044424 intracellular part

Nothing significant found in function category.