Motif ID: AAUCUCU

Z-value: 0.399


Mature miRNA associated with seed AAUCUCU:

NamemiRBase Accession
hsa-miR-216b MIMAT0004959



Activity profile for motif AAUCUCU.

activity profile for motif AAUCUCU


Sorted Z-values histogram for motif AAUCUCU

Sorted Z-values for motif AAUCUCU



Network of associatons between targets according to the STRING database.



First level regulatory network of AAUCUCU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_95044205 0.441 NM_020698
TMCC3
transmembrane and coiled-coil domain family 3
chr18_-_22932109 0.395 NM_015461
ZNF521
zinc finger protein 521
chr8_-_22550708 0.357 NM_004430
EGR3
early growth response 3
chr8_-_22549901 0.353 NM_001199880
EGR3
early growth response 3
chr8_-_22550057 0.346 NM_001199881
EGR3
early growth response 3
chr5_+_68788387 0.292 NM_001205254
OCLN
occludin
chr7_+_89840999 0.288 NM_001244944
NM_001244945
NM_152999
NM_001040665
NM_001244946
STEAP2




STEAP family member 2, metalloreductase




chr9_-_84303595 0.273 NM_005077
TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr6_+_136172802 0.271 NM_018945
PDE7B
phosphodiesterase 7B
chr12_+_27397077 0.268 NM_015000
STK38L
serine/threonine kinase 38 like
chr5_+_68800003 0.249 NM_001205255
OCLN
occludin
chr5_+_68788118 0.248 NM_002538
OCLN
occludin
chr15_-_71055745 0.237 NM_018003
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr3_-_148804122 0.228 NM_003071
NM_139048
HLTF

helicase-like transcription factor

chr1_+_109102970 0.219 NM_001010883
FAM102B
family with sequence similarity 102, member B
chr7_+_12250818 0.204 NM_001134232
NM_018374
TMEM106B

transmembrane protein 106B

chr10_-_81205091 0.199 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr15_-_70994608 0.198 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr9_+_43684800 0.187 NM_001201380
CNTNAP3B
contactin associated protein-like 3B
chr4_-_88141614 0.186 NM_020803
KLHL8
kelch-like 8 (Drosophila)
chr6_+_11538486 0.172 NM_001100829
TMEM170B
transmembrane protein 170B
chr8_+_76452202 0.170 NM_004133
HNF4G
hepatocyte nuclear factor 4, gamma
chr9_-_125027080 0.168 NM_033117
RBM18
RNA binding motif protein 18
chr7_-_105319608 0.162 NM_138495
ATXN7L1
ataxin 7-like 1
chr12_-_10022457 0.162 NM_005127
CLEC2B
C-type lectin domain family 2, member B
chr12_-_50236868 0.161 NM_181708
BCDIN3D
BCDIN3 domain containing
chr2_-_151344145 0.161 NM_005168
RND3
Rho family GTPase 3
chr6_+_42788793 0.157 NM_015349
KIAA0240
KIAA0240
chr18_+_59854514 0.157 NM_020854
KIAA1468
KIAA1468
chr4_-_90758126 0.155 NM_001146054
NM_007308
NM_000345
SNCA


synuclein, alpha (non A4 component of amyloid precursor)


chr4_-_90759446 0.153 NM_001146055
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr12_-_56615484 0.152 NM_001242826
RNF41
ring finger protein 41
chr19_+_41869848 0.152 NM_001098825
TMEM91
transmembrane protein 91
chr12_-_56615679 0.150 NM_005785
NM_194358
NM_194359
RNF41


ring finger protein 41


chr1_-_151882360 0.144 NM_053055
THEM4
thioesterase superfamily member 4
chr6_+_110501591 0.143 NM_015891
CDC40
cell division cycle 40 homolog (S. cerevisiae)
chr13_-_33760215 0.143 NM_001243466
NM_178007
STARD13

StAR-related lipid transfer (START) domain containing 13

chr13_-_33780142 0.142 NM_001243474
NM_052851
STARD13

StAR-related lipid transfer (START) domain containing 13

chr1_-_100715388 0.142 NM_001918
DBT
dihydrolipoamide branched chain transacylase E2
chr1_+_61547625 0.138 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr17_-_71088832 0.137 NM_001159770
NM_139177
SLC39A11

solute carrier family 39 (metal ion transporter), member 11

chr9_-_14693459 0.136 NM_178566
ZDHHC21
zinc finger, DHHC-type containing 21
chr7_-_92157748 0.136 NM_000466
PEX1
peroxisomal biogenesis factor 1
chr17_-_47439326 0.135 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chr1_+_61542928 0.133 NM_001145511
NFIA
nuclear factor I/A
chr7_+_90338711 0.131 NM_012395
CDK14
cyclin-dependent kinase 14
chr5_+_79783799 0.131 NM_205548
FAM151B
family with sequence similarity 151, member B
chr17_-_47755340 0.130 NM_001007226
NM_001007227
NM_001007228
NM_001007229
NM_001007230
NM_003563
SPOP





speckle-type POZ protein





chr1_-_220263150 0.130 NM_006085
BPNT1
3'(2'), 5'-bisphosphate nucleotidase 1
chr13_-_33859835 0.130 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr12_+_72233486 0.127 NM_001146213
NM_001146214
NM_022771
TBC1D15


TBC1 domain family, member 15


chr1_+_61547388 0.124 NM_001145512
NFIA
nuclear factor I/A
chr14_+_102228134 0.123 NM_001161725
NM_001161726
PPP2R5C

protein phosphatase 2, regulatory subunit B', gamma

chr19_-_23941571 0.121 NM_138286
ZNF681
zinc finger protein 681
chr3_-_125094003 0.121 NM_021964
ZNF148
zinc finger protein 148
chr11_+_94822937 0.120 NM_015036
ENDOD1
endonuclease domain containing 1
chr15_+_42867708 0.119 NM_020759
STARD9
StAR-related lipid transfer (START) domain containing 9
chr7_-_129845216 0.119 NM_032842
TMEM209
transmembrane protein 209
chr11_+_92085261 0.118 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr19_+_41882437 0.118 NM_001098821
NM_001098822
NM_001098823
NM_001098824
TMEM91



transmembrane protein 91



chr5_+_130506635 0.118 NM_181705
LYRM7
Lyrm7 homolog (mouse)
chr11_-_130184459 0.116 NM_014155
ZBTB44
zinc finger and BTB domain containing 44
chr16_+_8768403 0.115 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr6_+_96025343 0.115 NM_024641
MANEA
mannosidase, endo-alpha
chr16_+_8814567 0.113 NM_001127448
ABAT
4-aminobutyrate aminotransferase
chr4_-_135122902 0.112 NM_001114734
PABPC4L
poly(A) binding protein, cytoplasmic 4-like
chr4_+_71768056 0.112 NM_001244766
NM_001244767
NM_173468
MOB1B


MOB kinase activator 1B


chr8_-_19540093 0.111 NM_018371
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr9_+_115513050 0.110 NM_001012994
SNX30
sorting nexin family member 30
chr10_-_97321094 0.110 NM_015385
NM_024991
SORBS1

sorbin and SH3 domain containing 1

chr16_-_57520326 0.109 NM_018110
DOK4
docking protein 4
chr11_+_108093558 0.108 NM_000051
ATM
ataxia telangiectasia mutated
chr7_+_116502529 0.107 NM_006136
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr17_-_73975507 0.105 NM_001185039
NM_004035
NM_007292
ACOX1


acyl-CoA oxidase 1, palmitoyl


chr17_-_42767016 0.102 NM_001099225
NM_144609
CCDC43

coiled-coil domain containing 43

chr19_+_54024176 0.102 NM_018555
ZNF331
zinc finger protein 331
chr19_+_52901101 0.102 NM_032423
ZNF528
zinc finger protein 528
chr1_+_198125890 0.101 NM_133494
NEK7
NIMA (never in mitosis gene a)-related kinase 7
chr14_+_24899139 0.101 NM_015299
KHNYN
KH and NYN domain containing
chr2_+_113403433 0.099 NM_005415
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr9_-_126030854 0.097 NM_001171137
STRBP
spermatid perinuclear RNA binding protein
chr18_+_51885170 0.096 NM_173529
C18orf54
chromosome 18 open reading frame 54
chr16_+_8806825 0.096 NM_000663
ABAT
4-aminobutyrate aminotransferase
chr3_-_52479042 0.096 NM_020163
SEMA3G
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chr2_-_61245363 0.096 NM_144709
PUS10
pseudouridylate synthase 10
chr16_-_30457197 0.095 NM_012248
SEPHS2
selenophosphate synthetase 2
chr9_-_126030792 0.095 NM_018387
STRBP
spermatid perinuclear RNA binding protein
chr6_-_151712644 0.095 NM_020861
ZBTB2
zinc finger and BTB domain containing 2
chr22_+_21213248 0.095 NM_004782
SNAP29
synaptosomal-associated protein, 29kDa
chr8_+_22457098 0.094 NM_001013842
NM_001198827
NM_173686
C8orf58


chromosome 8 open reading frame 58


chr9_-_5833072 0.094 NM_024896
ERMP1
endoplasmic reticulum metallopeptidase 1
chrX_-_20284708 0.092 NM_004586
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr4_-_110650965 0.091 NM_030821
PLA2G12A
phospholipase A2, group XIIA
chr5_+_149151502 0.090 NM_001172699
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr12_+_60083125 0.090 NM_004731
SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr4_+_99916787 0.087 NM_015143
METAP1
methionyl aminopeptidase 1
chr10_-_97200895 0.087 NM_001034954
NM_001034955
NM_001034956
NM_001034957
NM_006434
SORBS1




sorbin and SH3 domain containing 1




chr16_-_49860917 0.087 NM_015069
ZNF423
zinc finger protein 423
chr8_-_19460005 0.087 NM_001130518
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr4_+_44680408 0.086 NM_021927
GUF1
GUF1 GTPase homolog (S. cerevisiae)
chr6_+_158957467 0.084 NM_020823
TMEM181
transmembrane protein 181
chr8_-_144923019 0.084 NM_178564
NRBP2
nuclear receptor binding protein 2
chr2_+_178257371 0.084 NM_003659
AGPS
alkylglycerone phosphate synthase
chr17_-_7382943 0.083 NM_001128833
ZBTB4
zinc finger and BTB domain containing 4
chr4_+_84457390 0.083 NM_032717
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr7_+_2598611 0.083 NM_001100390
NM_152558
IQCE

IQ motif containing E

chr19_+_54041332 0.081 NM_001079906
NM_001253798
NM_001253799
ZNF331


zinc finger protein 331


chr22_+_40440664 0.080 NM_001024843
TNRC6B
trinucleotide repeat containing 6B
chr1_-_114354906 0.079 NM_018364
RSBN1
round spermatid basic protein 1
chr18_-_29264394 0.078 NM_004775
B4GALT6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr3_-_113233952 0.078 NM_144718
SPICE1
spindle and centriole associated protein 1
chr17_+_37793332 0.078 NM_001165937
NM_001165938
NM_006804
STARD3


StAR-related lipid transfer (START) domain containing 3


chr17_+_76000248 0.078 NM_001142640
NM_018996
TNRC6C

trinucleotide repeat containing 6C

chr7_-_143582363 0.077 NM_001206941
FAM115A
family with sequence similarity 115, member A
chr1_+_53192021 0.077 NM_024646
ZYG11B
zyg-11 homolog B (C. elegans)
chr7_+_21467572 0.075 NM_003112
SP4
Sp4 transcription factor
chr7_-_143599163 0.075 NM_014719
NM_001206938
FAM115A

family with sequence similarity 115, member A

chrX_+_84258831 0.074 NM_198450
APOOL
apolipoprotein O-like
chr6_-_134373618 0.074 NM_145176
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr20_+_18122867 0.074 NM_020536
CSRP2BP
CSRP2 binding protein
chr7_+_35840595 0.073 NM_001011553
NM_001242956
NM_001788
SEPT7


septin 7


chr1_-_236030219 0.072 NM_000081
LYST
lysosomal trafficking regulator
chr1_+_109289266 0.072 NM_007269
STXBP3
syntaxin binding protein 3
chr6_-_80247103 0.072 NM_001122769
NM_181714
LCA5

Leber congenital amaurosis 5

chr5_-_87564615 0.072 NM_153354
TMEM161B
transmembrane protein 161B
chr8_-_92053043 0.071 NM_018710
TMEM55A
transmembrane protein 55A
chr20_+_54933982 0.071 NM_080821
FAM210B
family with sequence similarity 210, member B
chr3_+_183415540 0.070 NM_018023
YEATS2
YEATS domain containing 2
chrX_-_128977291 0.070 NM_001008222
ZDHHC9
zinc finger, DHHC-type containing 9
chr20_+_11871364 0.070 NM_181443
BTBD3
BTB (POZ) domain containing 3
chrX_+_105066531 0.069 NM_198465
NRK
Nik related kinase
chr6_+_7590405 0.069 NM_152551
SNRNP48
small nuclear ribonucleoprotein 48kDa (U11/U12)
chr15_+_65914269 0.069 NM_004727
SLC24A1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr4_+_81952118 0.067 NM_001201
BMP3
bone morphogenetic protein 3
chr3_-_121553907 0.067 NM_001023570
NM_001023571
IQCB1

IQ motif containing B1

chr12_+_38710556 0.067 NM_001013620
ALG10B
asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog B (yeast)
chr13_-_21476895 0.067 NM_022459
XPO4
exportin 4
chr9_+_35161950 0.067 NM_006377
UNC13B
unc-13 homolog B (C. elegans)
chr19_-_36980336 0.067 NM_032838
NM_001145343
NM_001145344
NM_001145345
ZNF566



zinc finger protein 566



chr8_+_48920969 0.066 NM_003350
UBE2V2
ubiquitin-conjugating enzyme E2 variant 2
chr12_-_8088629 0.065 NM_006931
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr3_+_101498028 0.064 NM_145037
FAM55C
family with sequence similarity 55, member C
chr6_-_107780682 0.063 NM_020381
PDSS2
prenyl (decaprenyl) diphosphate synthase, subunit 2
chr6_+_147525493 0.063 NM_001127715
NM_139244
STXBP5

syntaxin binding protein 5 (tomosyn)

chr22_-_24303317 0.063 NM_000854
NM_001080843
GSTT2
GSTT2B
glutathione S-transferase theta 2
glutathione S-transferase theta 2B (gene/pseudogene)
chr5_+_149109814 0.063 NM_001172698
NM_133263
PPARGC1B

peroxisome proliferator-activated receptor gamma, coactivator 1 beta

chr1_-_6296034 0.063 NM_012405
ICMT
isoprenylcysteine carboxyl methyltransferase
chr7_-_91875296 0.062 NM_194455
NM_194456
KRIT1

KRIT1, ankyrin repeat containing

chr20_+_11898536 0.062 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr7_-_91509979 0.062 NM_006980
MTERF
mitochondrial transcription termination factor
chr19_+_54058493 0.062 NM_001079907
ZNF331
zinc finger protein 331
chr3_-_88108047 0.062 NM_001008390
NM_003663
CGGBP1

CGG triplet repeat binding protein 1

chr9_-_4152182 0.061 NM_152629
GLIS3
GLIS family zinc finger 3
chr15_+_65822738 0.061 NM_016395
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr2_+_175260455 0.061 NM_001193528
NM_024583
SCRN3

secernin 3

chr12_+_123237302 0.061 NM_003677
DENR
density-regulated protein
chr16_-_19729417 0.061 NM_001012991
C16orf88
chromosome 16 open reading frame 88
chr2_+_203241044 0.060 NM_001204
BMPR2
bone morphogenetic protein receptor, type II (serine/threonine kinase)
chr12_-_26985922 0.060 NM_002223
ITPR2
inositol 1,4,5-trisphosphate receptor, type 2
chr14_-_35183722 0.060 NM_001243645
NM_138638
CFL2

cofilin 2 (muscle)

chr4_-_13629270 0.060 NM_148894
BOD1L
biorientation of chromosomes in cell division 1-like
chr17_-_7387513 0.059 NM_020899
ZBTB4
zinc finger and BTB domain containing 4
chr12_+_133613877 0.059 NM_003428
NM_001127372
ZNF84

zinc finger protein 84

chr9_+_33264876 0.059 NM_001195536
NM_016410
CHMP5

charged multivesicular body protein 5

chr1_+_15853348 0.059 NM_015291
DNAJC16
DnaJ (Hsp40) homolog, subfamily C, member 16
chr6_+_28317687 0.058 NM_001242894
NM_001242895
NM_024493
ZKSCAN3


zinc finger with KRAB and SCAN domains 3


chr7_-_99756275 0.058 NM_018275
C7orf43
chromosome 7 open reading frame 43
chr7_+_7222142 0.057 NM_020156
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr17_-_65241305 0.057 NM_014877
HELZ
helicase with zinc finger
chr12_+_111051831 0.056 NM_001082537
NM_001082538
NM_001173976
NM_024549
NM_001173975
TCTN1




tectonic family member 1




chr2_+_110371887 0.056 NM_023016
ANKRD57
ankyrin repeat domain 57
chr10_-_104473957 0.056 NM_004311
ARL3
ADP-ribosylation factor-like 3
chr22_+_40573879 0.056 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr9_-_124132503 0.055 NM_004099
NM_198194
STOM

stomatin

chrX_-_128977719 0.055 NM_016032
ZDHHC9
zinc finger, DHHC-type containing 9
chr4_+_78078332 0.054 NM_004354
CCNG2
cyclin G2
chr14_+_93673400 0.054 NM_175748
UBR7
ubiquitin protein ligase E3 component n-recognin 7 (putative)
chr22_-_19109912 0.054 NM_001173533
NM_001173534
NM_001184781
NM_005137
DGCR2



DiGeorge syndrome critical region gene 2



chr1_-_179112178 0.053 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr7_+_130794854 0.053 NM_001145354
MKLN1
muskelin 1, intracellular mediator containing kelch motifs
chr1_+_202509241 0.053 NM_001197131
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr12_+_27091304 0.052 NM_001171887
NM_001171888
NM_015633
FGFR1OP2


FGFR1 oncogene partner 2


chrX_+_117861523 0.052 NM_001560
IL13RA1
interleukin 13 receptor, alpha 1
chr5_-_93447237 0.052 NM_001163417
NM_001163418
NM_032042
FAM172A


family with sequence similarity 172, member A


chr14_+_102276125 0.052 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr8_-_133493003 0.051 NM_004519
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr3_-_112738514 0.051 NM_015412
C3orf17
chromosome 3 open reading frame 17
chr6_+_13574649 0.050 NM_001193267
NM_001242827
NM_031244
NM_012241
SIRT5



sirtuin 5



chr12_+_133757994 0.050 NM_001165883
NM_001165884
NM_001165885
NM_001165886
NM_001165887
NM_003415
NM_152943
NM_001165881
NM_001165882
ZNF268








zinc finger protein 268








chr12_+_56414688 0.049 NM_022465
IKZF4
IKAROS family zinc finger 4 (Eos)
chrX_+_74493893 0.049 NM_145052
UPRT
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr6_-_51952368 0.049 NM_138694
NM_170724
PKHD1

polycystic kidney and hepatic disease 1 (autosomal recessive)

chr11_+_86748870 0.048 NM_001168724
NM_022918
TMEM135

transmembrane protein 135

chr2_-_176866925 0.048 NM_030650
KIAA1715
KIAA1715
chr7_+_131012594 0.048 NM_013255
MKLN1
muskelin 1, intracellular mediator containing kelch motifs
chr13_-_100624162 0.047 NM_033132
ZIC5
Zic family member 5
chr7_+_154862545 0.047 NM_024012
HTR5A
5-hydroxytryptamine (serotonin) receptor 5A
chr9_-_88897372 0.046 NM_030940
ISCA1
iron-sulfur cluster assembly 1 homolog (S. cerevisiae)
chr4_+_1340957 0.046 NM_020894
KIAA1530
KIAA1530
chr9_-_19102898 0.045 NM_017645
HAUS6
HAUS augmin-like complex, subunit 6

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.20 4.25e-02 GO:0043231 intracellular membrane-bounded organelle
1.20 4.59e-02 GO:0043227 membrane-bounded organelle

Nothing significant found in function category.